639282:DEFDS RS05365
gene id: 639282:DEFDS_RS05365
uniprot id: D3PD65
names: Cofactor
messages: Binds 1 FAD per subunit.

639282:DEFDS RS03665
gene id: 639282:DEFDS_RS03665
uniprot id: D3PC84
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS00895
gene id: 639282:DEFDS_RS00895
uniprot id: D3PAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

639282:DEFDS RS01925
gene id: 639282:DEFDS_RS01925
uniprot id: D3PBA5
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS05160
gene id: 639282:DEFDS_RS05160
uniprot id: D3PD25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

639282:DEFDS RS10940
gene id: 639282:DEFDS_RS10940
uniprot id: D3PA69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS05925
gene id: 639282:DEFDS_RS05925
uniprot id: D3PDH5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

639282:DEFDS RS09120
gene id: 639282:DEFDS_RS09120
uniprot id: D3P974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

639282:DEFDS RS00485
gene id: 639282:DEFDS_RS00485
uniprot id: D3PAI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

639282:DEFDS RS06035
gene id: 639282:DEFDS_RS06035
uniprot id: D3PDJ3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

639282:DEFDS RS00460
gene id: 639282:DEFDS_RS00460
uniprot id: D3PAH9
names: Similarity
messages: Belongs to the threonine synthase family.

639282:DEFDS RS02440
gene id: 639282:DEFDS_RS02440
uniprot id: D3PBK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

639282:DEFDS RS10895
gene id: 639282:DEFDS_RS10895
uniprot id: D3PA60
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

639282:DEFDS RS00370
gene id: 639282:DEFDS_RS00370
uniprot id: D3PAG3
names: Similarity
messages: Belongs to the peptidase A31 family.

639282:DEFDS RS07520
gene id: 639282:DEFDS_RS07520
uniprot id: D3PED2
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS08400
gene id: 639282:DEFDS_RS08400
uniprot id: D3P8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS08900
gene id: 639282:DEFDS_RS08900
uniprot id: D3P935
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

639282:DEFDS RS09350
gene id: 639282:DEFDS_RS09350
uniprot id: D3P9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

639282:DEFDS RS05795
gene id: 639282:DEFDS_RS05795
uniprot id: D3PDE9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS07920
gene id: 639282:DEFDS_RS07920
uniprot id: D3P8J5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

639282:DEFDS RS01750
gene id: 639282:DEFDS_RS01750
uniprot id: D3PB75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

639282:DEFDS RS12500
gene id: 639282:DEFDS_RS12500
uniprot id: D3PAU3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

639282:DEFDS RS08590
gene id: 639282:DEFDS_RS08590
uniprot id: D3P8X5
names: Similarity
messages: Belongs to the MEMO1 family.

639282:DEFDS RS02965
gene id: 639282:DEFDS_RS02965
uniprot id: D3PBV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

639282:DEFDS RS09760
gene id: 639282:DEFDS_RS09760
uniprot id: D3P9J5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

639282:DEFDS RS07415
gene id: 639282:DEFDS_RS07415
uniprot id: D3PEB2
names: Similarity
messages: Belongs to the P(II) protein family.

639282:DEFDS RS04575
gene id: 639282:DEFDS_RS04575
uniprot id: D3PCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS10485
gene id: 639282:DEFDS_RS10485
uniprot id: D3P9Y8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

639282:DEFDS RS10035
gene id: 639282:DEFDS_RS10035
uniprot id: D3P9P9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

639282:DEFDS RS01330
gene id: 639282:DEFDS_RS01330
uniprot id: D3PAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

639282:DEFDS RS09515
gene id: 639282:DEFDS_RS09515
uniprot id: D3P9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

639282:DEFDS RS00655
gene id: 639282:DEFDS_RS00655
uniprot id: D3PAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

639282:DEFDS RS05000
gene id: 639282:DEFDS_RS05000
uniprot id: D3PCZ3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

639282:DEFDS RS08205
gene id: 639282:DEFDS_RS08205
uniprot id: D3P8Q1
names: Subcellular Location Annotation
messages: Cytoplasm

639282:DEFDS RS04745
gene id: 639282:DEFDS_RS04745
uniprot id: D3PCU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

639282:DEFDS RS10445
gene id: 639282:DEFDS_RS10445
uniprot id: D3P9Y0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS05865
gene id: 639282:DEFDS_RS05865
uniprot id: D3PDG3
names: Similarity
messages: Belongs to the thioredoxin family.

639282:DEFDS RS05995
gene id: 639282:DEFDS_RS05995
uniprot id: D3PDI7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

639282:DEFDS RS05020
gene id: 639282:DEFDS_RS05020
uniprot id: D3PCZ7
names: Similarity
messages: Belongs to the ycf81 family.

639282:DEFDS RS06800
gene id: 639282:DEFDS_RS06800
uniprot id: D3PDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS03265
gene id: 639282:DEFDS_RS03265
uniprot id: D3PC11
names: Similarity
messages: Belongs to the leucine-binding protein family.

639282:DEFDS RS01775
gene id: 639282:DEFDS_RS01775
uniprot id: D3PB80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

639282:DEFDS RS02200
gene id: 639282:DEFDS_RS02200
uniprot id: D3PBG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS07735
gene id: 639282:DEFDS_RS07735
uniprot id: D3PEH6
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

639282:DEFDS RS02785
gene id: 639282:DEFDS_RS02785
uniprot id: D3PBS1
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS03275
gene id: 639282:DEFDS_RS03275
uniprot id: D3PC13
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS07940
gene id: 639282:DEFDS_RS07940
uniprot id: D3P8J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

639282:DEFDS RS06785
gene id: 639282:DEFDS_RS06785
uniprot id: D3PDY8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

639282:DEFDS RS08635
gene id: 639282:DEFDS_RS08635
uniprot id: D3P8Y3
names: Similarity
messages: Belongs to the MotB family.

639282:DEFDS RS07965
gene id: 639282:DEFDS_RS07965
uniprot id: D3P8K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

639282:DEFDS RS03660
gene id: 639282:DEFDS_RS03660
uniprot id: D3PC83
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS08745
gene id: 639282:DEFDS_RS08745
uniprot id: D3P904
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS01355
gene id: 639282:DEFDS_RS01355
uniprot id: D3PB01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

639282:DEFDS RS03975
gene id: 639282:DEFDS_RS03975
uniprot id: D3PCE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

639282:DEFDS RS05640
gene id: 639282:DEFDS_RS05640
uniprot id: D3PDB9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

639282:DEFDS RS02485
gene id: 639282:DEFDS_RS02485
uniprot id: D3PBL7
names: Similarity
messages: Belongs to the peptidase M16 family.

639282:DEFDS RS00080
gene id: 639282:DEFDS_RS00080
uniprot id: D3PAA5
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS00025
gene id: 639282:DEFDS_RS00025
uniprot id: D3PA94
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS06135
gene id: 639282:DEFDS_RS06135
uniprot id: D3PDL3
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

639282:DEFDS RS02665
gene id: 639282:DEFDS_RS02665
uniprot id: D3PBQ1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

639282:DEFDS RS05345
gene id: 639282:DEFDS_RS05345
uniprot id: D3PD61
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS02280
gene id: 639282:DEFDS_RS02280
uniprot id: D3PBH7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

639282:DEFDS RS03365
gene id: 639282:DEFDS_RS03365
uniprot id: D3PC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

639282:DEFDS RS09865
gene id: 639282:DEFDS_RS09865
uniprot id: D3P9L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

639282:DEFDS RS08780
gene id: 639282:DEFDS_RS08780
uniprot id: D3P911
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

639282:DEFDS RS08815
gene id: 639282:DEFDS_RS08815
uniprot id: D3P918
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

639282:DEFDS RS09675
gene id: 639282:DEFDS_RS09675
uniprot id: D3P9H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

639282:DEFDS RS01220
gene id: 639282:DEFDS_RS01220
uniprot id: D3PAX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

639282:DEFDS RS08640
gene id: 639282:DEFDS_RS08640
uniprot id: D3P8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

639282:DEFDS RS01110
gene id: 639282:DEFDS_RS01110
uniprot id: D3PAV5
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS08430
gene id: 639282:DEFDS_RS08430
uniprot id: D3P8U4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

639282:DEFDS RS09455
gene id: 639282:DEFDS_RS09455
uniprot id: D3P9E0
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS08040
gene id: 639282:DEFDS_RS08040
uniprot id: D3P8L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS05240
gene id: 639282:DEFDS_RS05240
uniprot id: D3PD41
names: Similarity
messages: Belongs to the sigma-54 factor family.

639282:DEFDS RS04655
gene id: 639282:DEFDS_RS04655
uniprot id: D3PCS5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

639282:DEFDS RS02630
gene id: 639282:DEFDS_RS02630
uniprot id: D3PBP4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

639282:DEFDS RS08770
gene id: 639282:DEFDS_RS08770
uniprot id: D3P909
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

639282:DEFDS RS00385
gene id: 639282:DEFDS_RS00385
uniprot id: D3PAG6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

639282:DEFDS RS02835
gene id: 639282:DEFDS_RS02835
uniprot id: D3PBT1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

639282:DEFDS RS08340
gene id: 639282:DEFDS_RS08340
uniprot id: D3P8S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

639282:DEFDS RS00645
gene id: 639282:DEFDS_RS00645
uniprot id: D3PAL6
names: Similarity
messages: Belongs to the ParB family.

639282:DEFDS RS00700
gene id: 639282:DEFDS_RS00700
uniprot id: D3PAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

639282:DEFDS RS09180
gene id: 639282:DEFDS_RS09180
uniprot id: D3P986
names: Subcellular Location Annotation
messages: Cytoplasm

639282:DEFDS RS05575
gene id: 639282:DEFDS_RS05575
uniprot id: D3PDA6
names: Similarity
messages: Belongs to the GSP E family.

639282:DEFDS RS03925
gene id: 639282:DEFDS_RS03925
uniprot id: D3PCD6
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

639282:DEFDS RS10930
gene id: 639282:DEFDS_RS10930
uniprot id: D3PA67
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

639282:DEFDS RS02345
gene id: 639282:DEFDS_RS02345
uniprot id: D3PBJ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

639282:DEFDS RS05380
gene id: 639282:DEFDS_RS05380
uniprot id: D3PD67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

639282:DEFDS RS00520
gene id: 639282:DEFDS_RS00520
uniprot id: D3PAJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS09275
gene id: 639282:DEFDS_RS09275
uniprot id: D3P9A5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

639282:DEFDS RS06905
gene id: 639282:DEFDS_RS06905
uniprot id: D3PE11
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

639282:DEFDS RS02960
gene id: 639282:DEFDS_RS02960
uniprot id: D3PBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

639282:DEFDS RS08380
gene id: 639282:DEFDS_RS08380
uniprot id: D3P8T4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS04150
gene id: 639282:DEFDS_RS04150
uniprot id: D3PCH8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

639282:DEFDS RS00525
gene id: 639282:DEFDS_RS00525
uniprot id: D3PAJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

639282:DEFDS RS08785
gene id: 639282:DEFDS_RS08785
uniprot id: D3P912
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

639282:DEFDS RS01690
gene id: 639282:DEFDS_RS01690
uniprot id: D3PB63
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS08945
gene id: 639282:DEFDS_RS08945
uniprot id: D3P944
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

639282:DEFDS RS01135
gene id: 639282:DEFDS_RS01135
uniprot id: D3PAW0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

639282:DEFDS RS08070
gene id: 639282:DEFDS_RS08070
uniprot id: D3P8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

639282:DEFDS RS05085
gene id: 639282:DEFDS_RS05085
uniprot id: D3PD10
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

639282:DEFDS RS01270
gene id: 639282:DEFDS_RS01270
uniprot id: D3PAY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

639282:DEFDS RS00130
gene id: 639282:DEFDS_RS00130
uniprot id: D3PAB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

639282:DEFDS RS10845
gene id: 639282:DEFDS_RS10845
uniprot id: D3PA50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

639282:DEFDS RS07320
gene id: 639282:DEFDS_RS07320
uniprot id: D3PE93
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

639282:DEFDS RS02230
gene id: 639282:DEFDS_RS02230
uniprot id: D3PBG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

639282:DEFDS RS08540
gene id: 639282:DEFDS_RS08540
uniprot id: D3P8W6
names: Similarity
messages: Belongs to the UPF0251 family.

639282:DEFDS RS11705
gene id: 639282:DEFDS_RS11705
uniprot id: D3PAY0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

639282:DEFDS RS00200
gene id: 639282:DEFDS_RS00200
uniprot id: D3PAC9
names: Similarity
messages: Belongs to the CinA family.

639282:DEFDS RS08005
gene id: 639282:DEFDS_RS08005
uniprot id: D3P8L2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

639282:DEFDS RS03960
gene id: 639282:DEFDS_RS03960
uniprot id: D3PCE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

639282:DEFDS RS07645
gene id: 639282:DEFDS_RS07645
uniprot id: D3PEF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

639282:DEFDS RS01125
gene id: 639282:DEFDS_RS01125
uniprot id: D3PAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

639282:DEFDS RS09845
gene id: 639282:DEFDS_RS09845
uniprot id: D3P9L1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

639282:DEFDS RS10950
gene id: 639282:DEFDS_RS10950
uniprot id: D3PA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS00765
gene id: 639282:DEFDS_RS00765
uniprot id: D3PAP0
names: Similarity
messages: Belongs to the fabD family.

639282:DEFDS RS03000
gene id: 639282:DEFDS_RS03000
uniprot id: D3PBW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

639282:DEFDS RS05005
gene id: 639282:DEFDS_RS05005
uniprot id: D3PCZ4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

639282:DEFDS RS07615
gene id: 639282:DEFDS_RS07615
uniprot id: D3PEF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS10975
gene id: 639282:DEFDS_RS10975
uniprot id: D3PA75
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

639282:DEFDS RS02560
gene id: 639282:DEFDS_RS02560
uniprot id: D3PBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

639282:DEFDS RS00595
gene id: 639282:DEFDS_RS00595
uniprot id: D3PAK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

639282:DEFDS RS00570
gene id: 639282:DEFDS_RS00570
uniprot id: D3PAK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

639282:DEFDS RS08880
gene id: 639282:DEFDS_RS08880
uniprot id: D3P931
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

639282:DEFDS RS00590
gene id: 639282:DEFDS_RS00590
uniprot id: D3PAK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

639282:DEFDS RS08490
gene id: 639282:DEFDS_RS08490
uniprot id: D3P8V6
names: Similarity
messages: Belongs to the UPF0251 family.

639282:DEFDS RS09985
gene id: 639282:DEFDS_RS09985
uniprot id: D3P9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

639282:DEFDS RS03075
gene id: 639282:DEFDS_RS03075
uniprot id: D3PBX4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

639282:DEFDS RS11625
gene id: 639282:DEFDS_RS11625
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS02515
gene id: 639282:DEFDS_RS02515
uniprot id: D3PBM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

639282:DEFDS RS01230
gene id: 639282:DEFDS_RS01230
uniprot id: D3PAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

639282:DEFDS RS05385
gene id: 639282:DEFDS_RS05385
uniprot id: D3PD68
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

639282:DEFDS RS02285
gene id: 639282:DEFDS_RS02285
uniprot id: D3PBH8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

639282:DEFDS RS03435
gene id: 639282:DEFDS_RS03435
uniprot id: D3PC42
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

639282:DEFDS RS01990
gene id: 639282:DEFDS_RS01990
uniprot id: D3PBB9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS00850
gene id: 639282:DEFDS_RS00850
uniprot id: D3PAQ7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

639282:DEFDS RS08875
gene id: 639282:DEFDS_RS08875
uniprot id: D3P930
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

639282:DEFDS RS09935
gene id: 639282:DEFDS_RS09935
uniprot id: D3P9M9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

639282:DEFDS RS02235
gene id: 639282:DEFDS_RS02235
uniprot id: D3PBG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

639282:DEFDS RS06440
gene id: 639282:DEFDS_RS06440
uniprot id: D3PDS5
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

639282:DEFDS RS03890
gene id: 639282:DEFDS_RS03890
uniprot id: D3PCC9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

639282:DEFDS RS04300
gene id: 639282:DEFDS_RS04300
uniprot id: D3PCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

639282:DEFDS RS03025
gene id: 639282:DEFDS_RS03025
uniprot id: D3PBW9
names: Similarity
messages: Belongs to the UPF0166 family.

639282:DEFDS RS08840
gene id: 639282:DEFDS_RS08840
uniprot id: D3P923
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

639282:DEFDS RS05505
gene id: 639282:DEFDS_RS05505
uniprot id: D3PD92
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

639282:DEFDS RS07400
gene id: 639282:DEFDS_RS07400
uniprot id: D3PEA9
names: Similarity
messages: Belongs to the CFA/CMAS family.

639282:DEFDS RS07795
gene id: 639282:DEFDS_RS07795
uniprot id: D3P8H1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS08645
gene id: 639282:DEFDS_RS08645
uniprot id: D3P8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

639282:DEFDS RS10225
gene id: 639282:DEFDS_RS10225
uniprot id: D3P9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS02955
gene id: 639282:DEFDS_RS02955
uniprot id: D3PBV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS10890
gene id: 639282:DEFDS_RS10890
uniprot id: D3PA59
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

639282:DEFDS RS07555
gene id: 639282:DEFDS_RS07555
uniprot id: D3PED9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

639282:DEFDS RS02690
gene id: 639282:DEFDS_RS02690
uniprot id: D3PBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

639282:DEFDS RS02980
gene id: 639282:DEFDS_RS02980
uniprot id: D3PBW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

639282:DEFDS RS09130
gene id: 639282:DEFDS_RS09130
uniprot id: D3P976
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

639282:DEFDS RS04070
gene id: 639282:DEFDS_RS04070
uniprot id: D3PCG4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

639282:DEFDS RS00495
gene id: 639282:DEFDS_RS00495
uniprot id: D3PAI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

639282:DEFDS RS08125
gene id: 639282:DEFDS_RS08125
uniprot id: D3P8N5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

639282:DEFDS RS08955
gene id: 639282:DEFDS_RS08955
uniprot id: D3P946
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

639282:DEFDS RS04740
gene id: 639282:DEFDS_RS04740
uniprot id: D3PCU2
names: Similarity
messages: Belongs to the TlyA family.

639282:DEFDS RS12620
gene id: 639282:DEFDS_RS12620
uniprot id: D3PD96
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

639282:DEFDS RS06130
gene id: 639282:DEFDS_RS06130
uniprot id: D3PDL2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS04030
gene id: 639282:DEFDS_RS04030
uniprot id: D3PCF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS09680
gene id: 639282:DEFDS_RS09680
uniprot id: D3P9H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

639282:DEFDS RS01590
gene id: 639282:DEFDS_RS01590
uniprot id: D3PB44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

639282:DEFDS RS06565
gene id: 639282:DEFDS_RS06565
uniprot id: D3PDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS08920
gene id: 639282:DEFDS_RS08920
uniprot id: D3P939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

639282:DEFDS RS05770
gene id: 639282:DEFDS_RS05770
uniprot id: D3PDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

639282:DEFDS RS01455
gene id: 639282:DEFDS_RS01455
uniprot id: D3PB19
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

639282:DEFDS RS00535
gene id: 639282:DEFDS_RS00535
uniprot id: D3PAJ4
names: Similarity
messages: Belongs to the Skp family.

639282:DEFDS RS08455
gene id: 639282:DEFDS_RS08455
uniprot id: D3P8U9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

639282:DEFDS RS08495
gene id: 639282:DEFDS_RS08495
uniprot id: D3P8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

639282:DEFDS RS12575
gene id: 639282:DEFDS_RS12575
uniprot id: D3PCL9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS12700
gene id: 639282:DEFDS_RS12700
uniprot id: D3PEI2
names: Similarity
messages: Belongs to the hemerythrin family.

639282:DEFDS RS00715
gene id: 639282:DEFDS_RS00715
uniprot id: D3PAN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

639282:DEFDS RS09360
gene id: 639282:DEFDS_RS09360
uniprot id: D3P9C2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

639282:DEFDS RS10020
gene id: 639282:DEFDS_RS10020
uniprot id: D3P9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

639282:DEFDS RS11880
gene id: 639282:DEFDS_RS11880
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS02105
gene id: 639282:DEFDS_RS02105
uniprot id: D3PBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

639282:DEFDS RS02270
gene id: 639282:DEFDS_RS02270
uniprot id: D3PBH5
names: Similarity
messages: Belongs to the peptidase M24B family.

639282:DEFDS RS10305
gene id: 639282:DEFDS_RS10305
uniprot id: D3P9V3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

639282:DEFDS RS07985
gene id: 639282:DEFDS_RS07985
uniprot id: D3P8K8
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS10655
gene id: 639282:DEFDS_RS10655
uniprot id: D3PA21
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

639282:DEFDS RS02780
gene id: 639282:DEFDS_RS02780
uniprot id: D3PBS0
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS09650
gene id: 639282:DEFDS_RS09650
uniprot id: D3P9H3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

639282:DEFDS RS09065
gene id: 639282:DEFDS_RS09065
uniprot id: D3P963
names: Similarity
messages: Belongs to the DEAD box helicase family.

639282:DEFDS RS09920
gene id: 639282:DEFDS_RS09920
uniprot id: D3P9M6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

639282:DEFDS RS10555
gene id: 639282:DEFDS_RS10555
uniprot id: D3PA01
names: Similarity
messages: Belongs to the peptidase S49 family.

639282:DEFDS RS08660
gene id: 639282:DEFDS_RS08660
uniprot id: D3P8Y8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

639282:DEFDS RS06540
gene id: 639282:DEFDS_RS06540
uniprot id: D3PDU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

639282:DEFDS RS07550
gene id: 639282:DEFDS_RS07550
uniprot id: D3PED8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

639282:DEFDS RS10580
gene id: 639282:DEFDS_RS10580
uniprot id: D3PA06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

639282:DEFDS RS03155
gene id: 639282:DEFDS_RS03155
uniprot id: D3PBZ0
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS05215
gene id: 639282:DEFDS_RS05215
uniprot id: D3PD36
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

639282:DEFDS RS08985
gene id: 639282:DEFDS_RS08985
uniprot id: D3P951
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

639282:DEFDS RS00285
gene id: 639282:DEFDS_RS00285
uniprot id: D3PAE6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

639282:DEFDS RS06370
gene id: 639282:DEFDS_RS06370
uniprot id: D3PDR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

639282:DEFDS RS02525
gene id: 639282:DEFDS_RS02525
uniprot id: D3PBM4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

639282:DEFDS RS02330
gene id: 639282:DEFDS_RS02330
uniprot id: D3PBI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

639282:DEFDS RS00195
gene id: 639282:DEFDS_RS00195
uniprot id: D3PAC8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

639282:DEFDS RS12220
gene id: 639282:DEFDS_RS12220
uniprot id: D3PF42
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

639282:DEFDS RS08700
gene id: 639282:DEFDS_RS08700
uniprot id: D3P8Z5
names: Similarity
messages: Belongs to the HypE family.

639282:DEFDS RS00270
gene id: 639282:DEFDS_RS00270
uniprot id: D3PAE3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

639282:DEFDS RS05055
gene id: 639282:DEFDS_RS05055
uniprot id: D3PD04
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

639282:DEFDS RS05615
gene id: 639282:DEFDS_RS05615
uniprot id: D3PDB4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

639282:DEFDS RS04625
gene id: 639282:DEFDS_RS04625
uniprot id: D3PCR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

639282:DEFDS RS00050
gene id: 639282:DEFDS_RS00050
uniprot id: D3PA99
names: Similarity
messages: Belongs to the UPF0173 family.

639282:DEFDS RS00620
gene id: 639282:DEFDS_RS00620
uniprot id: D3PAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

639282:DEFDS RS01585
gene id: 639282:DEFDS_RS01585
uniprot id: D3PB43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

639282:DEFDS RS02340
gene id: 639282:DEFDS_RS02340
uniprot id: D3PBI9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS00925
gene id: 639282:DEFDS_RS00925
uniprot id: D3PAR8
names: Similarity
messages: Belongs to the UPF0102 family.

639282:DEFDS RS07205
gene id: 639282:DEFDS_RS07205
uniprot id: D3PE70
names: Subcellular Location Annotation
messages: Cytoplasm

639282:DEFDS RS02470
gene id: 639282:DEFDS_RS02470
uniprot id: D3PBL4
names: Similarity
messages: Belongs to the histone deacetylase family.

639282:DEFDS RS05105
gene id: 639282:DEFDS_RS05105
uniprot id: D3PD14
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

639282:DEFDS RS05165
gene id: 639282:DEFDS_RS05165
uniprot id: D3PD26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

639282:DEFDS RS02545
gene id: 639282:DEFDS_RS02545
uniprot id: D3PBM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

639282:DEFDS RS06450
gene id: 639282:DEFDS_RS06450
uniprot id: D3PDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

639282:DEFDS RS08950
gene id: 639282:DEFDS_RS08950
uniprot id: D3P945
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

639282:DEFDS RS10800
gene id: 639282:DEFDS_RS10800
uniprot id: D3PA48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

639282:DEFDS RS09075
gene id: 639282:DEFDS_RS09075
uniprot id: D3P965
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

639282:DEFDS RS10295
gene id: 639282:DEFDS_RS10295
uniprot id: D3P9V1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

639282:DEFDS RS06245
gene id: 639282:DEFDS_RS06245
uniprot id: D3PDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

639282:DEFDS RS01755
gene id: 639282:DEFDS_RS01755
uniprot id: D3PB76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

639282:DEFDS RS11410
gene id: 639282:DEFDS_RS11410
uniprot id: D3PEQ0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

639282:DEFDS RS10610
gene id: 639282:DEFDS_RS10610
uniprot id: D3PA12
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

639282:DEFDS RS10705
gene id: 639282:DEFDS_RS10705
uniprot id: D3PA29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

639282:DEFDS RS02885
gene id: 639282:DEFDS_RS02885
uniprot id: D3PBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

639282:DEFDS RS08245
gene id: 639282:DEFDS_RS08245
uniprot id: D3P8Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

639282:DEFDS RS05520
gene id: 639282:DEFDS_RS05520
uniprot id: D3PD95
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

639282:DEFDS RS06890
gene id: 639282:DEFDS_RS06890
uniprot id: D3PE08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

639282:DEFDS RS09550
gene id: 639282:DEFDS_RS09550
uniprot id: D3P9F4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

639282:DEFDS RS07655
gene id: 639282:DEFDS_RS07655
uniprot id: D3PEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

639282:DEFDS RS08820
gene id: 639282:DEFDS_RS08820
uniprot id: D3P919
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

639282:DEFDS RS05125
gene id: 639282:DEFDS_RS05125
uniprot id: D3PD18
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

639282:DEFDS RS12145
gene id: 639282:DEFDS_RS12145
uniprot id: D3PF27
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

639282:DEFDS RS09880
gene id: 639282:DEFDS_RS09880
uniprot id: D3P9L8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS04780
gene id: 639282:DEFDS_RS04780
uniprot id: D3PCV0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

639282:DEFDS RS05150
gene id: 639282:DEFDS_RS05150
uniprot id: D3PD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

639282:DEFDS RS04245
gene id: 639282:DEFDS_RS04245
uniprot id: D3PCJ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

639282:DEFDS RS05910
gene id: 639282:DEFDS_RS05910
uniprot id: D3PDH2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

639282:DEFDS RS02510
gene id: 639282:DEFDS_RS02510
uniprot id: D3PBM1
names: Similarity
messages: Belongs to the IMPACT family.

639282:DEFDS RS04395
gene id: 639282:DEFDS_RS04395
uniprot id: D3PAY0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

639282:DEFDS RS11020
gene id: 639282:DEFDS_RS11020
uniprot id: D3PA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

639282:DEFDS RS04085
gene id: 639282:DEFDS_RS04085
uniprot id: D3PCG7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

639282:DEFDS RS03180
gene id: 639282:DEFDS_RS03180
uniprot id: D3PBZ5
names: Similarity
messages: Belongs to the acylphosphatase family.

639282:DEFDS RS06950
gene id: 639282:DEFDS_RS06950
uniprot id: D3PE19
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

639282:DEFDS RS12015
gene id: 639282:DEFDS_RS12015
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS05550
gene id: 639282:DEFDS_RS05550
uniprot id: D3PDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

639282:DEFDS RS06360
gene id: 639282:DEFDS_RS06360
uniprot id: D3PDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

639282:DEFDS RS07675
gene id: 639282:DEFDS_RS07675
uniprot id: D3PEG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

639282:DEFDS RS11505
gene id: 639282:DEFDS_RS11505
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS04865
gene id: 639282:DEFDS_RS04865
uniprot id: D3PCW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS02410
gene id: 639282:DEFDS_RS02410
uniprot id: D3PBK2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

639282:DEFDS RS05820
gene id: 639282:DEFDS_RS05820
uniprot id: D3PDF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

639282:DEFDS RS06335
gene id: 639282:DEFDS_RS06335
uniprot id: D3PDQ4
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

639282:DEFDS RS03675
gene id: 639282:DEFDS_RS03675
uniprot id: D3PC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

639282:DEFDS RS10325
gene id: 639282:DEFDS_RS10325
uniprot id: D3P9V7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

639282:DEFDS RS03715
gene id: 639282:DEFDS_RS03715
uniprot id: D3PC94
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

639282:DEFDS RS02455
gene id: 639282:DEFDS_RS02455
uniprot id: D3PBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

639282:DEFDS RS10270
gene id: 639282:DEFDS_RS10270
uniprot id: D3P9U7
names: Similarity
messages: Belongs to the peptidase C56 family.

639282:DEFDS RS00545
gene id: 639282:DEFDS_RS00545
uniprot id: D3PAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

639282:DEFDS RS11745
gene id: 639282:DEFDS_RS11745
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS08790
gene id: 639282:DEFDS_RS08790
uniprot id: D3P913
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

639282:DEFDS RS10660
gene id: 639282:DEFDS_RS10660
uniprot id: D3PA22
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

639282:DEFDS RS00690
gene id: 639282:DEFDS_RS00690
uniprot id: D3PAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

639282:DEFDS RS00190
gene id: 639282:DEFDS_RS00190
uniprot id: D3PAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

639282:DEFDS RS10245
gene id: 639282:DEFDS_RS10245
uniprot id: D3P9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

639282:DEFDS RS04260
gene id: 639282:DEFDS_RS04260
uniprot id: D3PCK0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

639282:DEFDS RS03150
gene id: 639282:DEFDS_RS03150
uniprot id: D3PBY9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS02075
gene id: 639282:DEFDS_RS02075
uniprot id: D3PBD6
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

639282:DEFDS RS08710
gene id: 639282:DEFDS_RS08710
uniprot id: D3P8Z7
names: Similarity
messages: Belongs to the HupF/HypC family.

639282:DEFDS RS02935
gene id: 639282:DEFDS_RS02935
uniprot id: D3PBV1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

639282:DEFDS RS04230
gene id: 639282:DEFDS_RS04230
uniprot id: D3PCJ4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

639282:DEFDS RS07805
gene id: 639282:DEFDS_RS07805
uniprot id: D3P8H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS05335
gene id: 639282:DEFDS_RS05335
uniprot id: D3PD59
names: Similarity
messages: Belongs to the leucine-binding protein family.

639282:DEFDS RS06610
gene id: 639282:DEFDS_RS06610
uniprot id: D3PDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS02950
gene id: 639282:DEFDS_RS02950
uniprot id: D3PBV4
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS02430
gene id: 639282:DEFDS_RS02430
uniprot id: D3PBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS00720
gene id: 639282:DEFDS_RS00720
uniprot id: D3PAN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

639282:DEFDS RS00250
gene id: 639282:DEFDS_RS00250
uniprot id: D3PAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

639282:DEFDS RS00240
gene id: 639282:DEFDS_RS00240
uniprot id: D3PAD7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

639282:DEFDS RS00110
gene id: 639282:DEFDS_RS00110
uniprot id: D3PAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

639282:DEFDS RS09085
gene id: 639282:DEFDS_RS09085
uniprot id: D3P967
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

639282:DEFDS RS00675
gene id: 639282:DEFDS_RS00675
uniprot id: D3PAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS08775
gene id: 639282:DEFDS_RS08775
uniprot id: D3P910
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

639282:DEFDS RS08870
gene id: 639282:DEFDS_RS08870
uniprot id: D3P929
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

639282:DEFDS RS09995
gene id: 639282:DEFDS_RS09995
uniprot id: D3P9P1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

639282:DEFDS RS11260
gene id: 639282:DEFDS_RS11260
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS05975
gene id: 639282:DEFDS_RS05975
uniprot id: D3PDI3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

639282:DEFDS RS11030
gene id: 639282:DEFDS_RS11030
uniprot id: D3PA86
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

639282:DEFDS RS07195
gene id: 639282:DEFDS_RS07195
uniprot id: D3PE68
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

639282:DEFDS RS10965
gene id: 639282:DEFDS_RS10965
uniprot id: D3PA73
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

639282:DEFDS RS08690
gene id: 639282:DEFDS_RS08690
uniprot id: D3P8Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS05435
gene id: 639282:DEFDS_RS05435
uniprot id: D3PD78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

639282:DEFDS RS03205
gene id: 639282:DEFDS_RS03205
uniprot id: D3PC00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

639282:DEFDS RS02005
gene id: 639282:DEFDS_RS02005
uniprot id: D3PBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS01350
gene id: 639282:DEFDS_RS01350
uniprot id: D3PB00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

639282:DEFDS RS00475
gene id: 639282:DEFDS_RS00475
uniprot id: D3PAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

639282:DEFDS RS03540
gene id: 639282:DEFDS_RS03540
uniprot id: D3PC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

639282:DEFDS RS10425
gene id: 639282:DEFDS_RS10425
uniprot id: D3P9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS09080
gene id: 639282:DEFDS_RS09080
uniprot id: D3P966
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

639282:DEFDS RS06895
gene id: 639282:DEFDS_RS06895
uniprot id: D3PE09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

639282:DEFDS RS10545
gene id: 639282:DEFDS_RS10545
uniprot id: D3P9Z9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS00215
gene id: 639282:DEFDS_RS00215
uniprot id: D3PAD2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

639282:DEFDS RS00750
gene id: 639282:DEFDS_RS00750
uniprot id: D3PAN7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

639282:DEFDS RS08970
gene id: 639282:DEFDS_RS08970
uniprot id: D3P949
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

639282:DEFDS RS02445
gene id: 639282:DEFDS_RS02445
uniprot id: D3PBK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

639282:DEFDS RS05260
gene id: 639282:DEFDS_RS05260
uniprot id: D3PD45
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

639282:DEFDS RS04155
gene id: 639282:DEFDS_RS04155
uniprot id: D3PCH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

639282:DEFDS RS07160
gene id: 639282:DEFDS_RS07160
uniprot id: D3PE61
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

639282:DEFDS RS04755
gene id: 639282:DEFDS_RS04755
uniprot id: D3PCU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

639282:DEFDS RS04630
gene id: 639282:DEFDS_RS04630
uniprot id: D3PCS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

639282:DEFDS RS05940
gene id: 639282:DEFDS_RS05940
uniprot id: D3PDH8
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS06190
gene id: 639282:DEFDS_RS06190
uniprot id: D3PDM5
names: Similarity
messages: Belongs to the FGGY kinase family.

639282:DEFDS RS12785
gene id: 639282:DEFDS_RS12785
uniprot id: D3PEV9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

639282:DEFDS RS06850
gene id: 639282:DEFDS_RS06850
uniprot id: D3PE00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

639282:DEFDS RS08910
gene id: 639282:DEFDS_RS08910
uniprot id: D3P937
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

639282:DEFDS RS00375
gene id: 639282:DEFDS_RS00375
uniprot id: D3PAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

639282:DEFDS RS07370
gene id: 639282:DEFDS_RS07370
uniprot id: D3PEA3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

639282:DEFDS RS04010
gene id: 639282:DEFDS_RS04010
uniprot id: D3PCF2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

639282:DEFDS RS07410
gene id: 639282:DEFDS_RS07410
uniprot id: D3PEB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

639282:DEFDS RS05195
gene id: 639282:DEFDS_RS05195
uniprot id: D3PD32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

639282:DEFDS RS04975
gene id: 639282:DEFDS_RS04975
uniprot id: D3PCY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS04845
gene id: 639282:DEFDS_RS04845
uniprot id: D3PCW3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

639282:DEFDS RS10600
gene id: 639282:DEFDS_RS10600
uniprot id: D3PA10
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

639282:DEFDS RS08375
gene id: 639282:DEFDS_RS08375
uniprot id: D3P8T3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

639282:DEFDS RS06415
gene id: 639282:DEFDS_RS06415
uniprot id: D3PDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

639282:DEFDS RS07515
gene id: 639282:DEFDS_RS07515
uniprot id: D3PED1
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS00985
gene id: 639282:DEFDS_RS00985
uniprot id: D3PAT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

639282:DEFDS RS03320
gene id: 639282:DEFDS_RS03320
uniprot id: D3PC20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

639282:DEFDS RS07170
gene id: 639282:DEFDS_RS07170
uniprot id: D3PE63
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS12995
gene id: 639282:DEFDS_RS12995
uniprot id: D3P8X3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

639282:DEFDS RS09815
gene id: 639282:DEFDS_RS09815
uniprot id: D3P9K5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

639282:DEFDS RS03080
gene id: 639282:DEFDS_RS03080
uniprot id: D3PBX5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

639282:DEFDS RS02975
gene id: 639282:DEFDS_RS02975
uniprot id: D3PBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

639282:DEFDS RS10360
gene id: 639282:DEFDS_RS10360
uniprot id: D3P9W4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

639282:DEFDS RS11035
gene id: 639282:DEFDS_RS11035
uniprot id: D3PA87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

639282:DEFDS RS12290
gene id: 639282:DEFDS_RS12290
uniprot id: D3PF56
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

639282:DEFDS RS08170
gene id: 639282:DEFDS_RS08170
uniprot id: D3P8P4
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS08885
gene id: 639282:DEFDS_RS08885
uniprot id: D3P932
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

639282:DEFDS RS00680
gene id: 639282:DEFDS_RS00680
uniprot id: D3PAM3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

639282:DEFDS RS07790
gene id: 639282:DEFDS_RS07790
uniprot id: D3PEI7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

639282:DEFDS RS08810
gene id: 639282:DEFDS_RS08810
uniprot id: D3P917
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

639282:DEFDS RS08665
gene id: 639282:DEFDS_RS08665
uniprot id: D3P8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

639282:DEFDS RS00330
gene id: 639282:DEFDS_RS00330
uniprot id: D3PAF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS09665
gene id: 639282:DEFDS_RS09665
uniprot id: D3P9H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

639282:DEFDS RS05450
gene id: 639282:DEFDS_RS05450
uniprot id: D3PD81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

639282:DEFDS RS03270
gene id: 639282:DEFDS_RS03270
uniprot id: D3PC12
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS02100
gene id: 639282:DEFDS_RS02100
uniprot id: D3PBE1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

639282:DEFDS RS10315
gene id: 639282:DEFDS_RS10315
uniprot id: D3P9V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

639282:DEFDS RS02045
gene id: 639282:DEFDS_RS02045
uniprot id: D3PBD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS05190
gene id: 639282:DEFDS_RS05190
uniprot id: D3PD31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

639282:DEFDS RS12265
gene id: 639282:DEFDS_RS12265
uniprot id: D3PF51
names: Similarity
messages: Belongs to the RecJ family.

639282:DEFDS RS02760
gene id: 639282:DEFDS_RS02760
uniprot id: D3PBR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

639282:DEFDS RS10570
gene id: 639282:DEFDS_RS10570
uniprot id: D3PA04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

639282:DEFDS RS00010
gene id: 639282:DEFDS_RS00010
uniprot id: D3PA91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

639282:DEFDS RS07925
gene id: 639282:DEFDS_RS07925
uniprot id: D3P8J6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

639282:DEFDS RS05805
gene id: 639282:DEFDS_RS05805
uniprot id: D3PDF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS09300
gene id: 639282:DEFDS_RS09300
uniprot id: D3P9B0
names: Similarity
messages: Belongs to the UPF0047 family.

639282:DEFDS RS00725
gene id: 639282:DEFDS_RS00725
uniprot id: D3PAN2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

639282:DEFDS RS00610
gene id: 639282:DEFDS_RS00610
uniprot id: D3PAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

639282:DEFDS RS07700
gene id: 639282:DEFDS_RS07700
uniprot id: D3PEG9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

639282:DEFDS RS10550
gene id: 639282:DEFDS_RS10550
uniprot id: D3PA00
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

639282:DEFDS RS05035
gene id: 639282:DEFDS_RS05035
uniprot id: D3PD00
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

639282:DEFDS RS02405
gene id: 639282:DEFDS_RS02405
uniprot id: D3PBK1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

639282:DEFDS RS09380
gene id: 639282:DEFDS_RS09380
uniprot id: D3P9C5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

639282:DEFDS RS09240
gene id: 639282:DEFDS_RS09240
uniprot id: D3P998
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS10040
gene id: 639282:DEFDS_RS10040
uniprot id: D3P9Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

639282:DEFDS RS02465
gene id: 639282:DEFDS_RS02465
uniprot id: D3PBL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

639282:DEFDS RS07830
gene id: 639282:DEFDS_RS07830
uniprot id: D3P8H7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

639282:DEFDS RS07025
gene id: 639282:DEFDS_RS07025
uniprot id: D3PE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS04825
gene id: 639282:DEFDS_RS04825
uniprot id: D3PCV9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS12205
gene id: 639282:DEFDS_RS12205
uniprot id: D3PF39
names: Function
names: Similarity
messages: Belongs to the DnaA family.
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

639282:DEFDS RS05220
gene id: 639282:DEFDS_RS05220
uniprot id: D3PD37
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

639282:DEFDS RS04255
gene id: 639282:DEFDS_RS04255
uniprot id: D3PCJ9
names: Similarity
messages: Belongs to the hemerythrin family.

639282:DEFDS RS02615
gene id: 639282:DEFDS_RS02615
uniprot id: D3PBP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

639282:DEFDS RS07875
gene id: 639282:DEFDS_RS07875
uniprot id: D3P8I6
names: Similarity
messages: Belongs to the Fur family.

639282:DEFDS RS04140
gene id: 639282:DEFDS_RS04140
uniprot id: D3PCH6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

639282:DEFDS RS07150
gene id: 639282:DEFDS_RS07150
uniprot id: D3PE59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS09150
gene id: 639282:DEFDS_RS09150
uniprot id: D3P980
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

639282:DEFDS RS06535
gene id: 639282:DEFDS_RS06535
uniprot id: D3PDU4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS06960
gene id: 639282:DEFDS_RS06960
uniprot id: D3PE21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

639282:DEFDS RS00845
gene id: 639282:DEFDS_RS00845
uniprot id: D3PAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

639282:DEFDS RS00225
gene id: 639282:DEFDS_RS00225
uniprot id: D3PAD4
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS01290
gene id: 639282:DEFDS_RS01290
uniprot id: D3PAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

639282:DEFDS RS02460
gene id: 639282:DEFDS_RS02460
uniprot id: D3PBL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

639282:DEFDS RS06140
gene id: 639282:DEFDS_RS06140
uniprot id: D3PDL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

639282:DEFDS RS13095
gene id: 639282:DEFDS_RS13095
uniprot id: D3PCR4
names: Similarity
messages: Belongs to the class-I fumarase family.

639282:DEFDS RS05490
gene id: 639282:DEFDS_RS05490
uniprot id: D3PD89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

639282:DEFDS RS07305
gene id: 639282:DEFDS_RS07305
uniprot id: D3PE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS02275
gene id: 639282:DEFDS_RS02275
uniprot id: D3PBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

639282:DEFDS RS10850
gene id: 639282:DEFDS_RS10850
uniprot id: D3PA51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

639282:DEFDS RS04750
gene id: 639282:DEFDS_RS04750
uniprot id: D3PCU4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

639282:DEFDS RS09155
gene id: 639282:DEFDS_RS09155
uniprot id: D3P981
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

639282:DEFDS RS01100
gene id: 639282:DEFDS_RS01100
uniprot id: D3PAV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

639282:DEFDS RS09110
gene id: 639282:DEFDS_RS09110
uniprot id: D3P972
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

639282:DEFDS RS07600
gene id: 639282:DEFDS_RS07600
uniprot id: D3PEE9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

639282:DEFDS RS09670
gene id: 639282:DEFDS_RS09670
uniprot id: D3P9H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
messages: The residue potentially involved in the covalent binding of FMN is a Ser instead of a Thr.

639282:DEFDS RS08705
gene id: 639282:DEFDS_RS08705
uniprot id: D3P8Z6
names: Similarity
messages: Belongs to the HypD family.

639282:DEFDS RS00995
gene id: 639282:DEFDS_RS00995
uniprot id: D3PAT2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

639282:DEFDS RS13140
gene id: 639282:DEFDS_RS13140
uniprot id: D3PED0
names: Similarity
messages: Belongs to the leucine-binding protein family.

639282:DEFDS RS06430
gene id: 639282:DEFDS_RS06430
uniprot id: D3PDS3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

639282:DEFDS RS01300
gene id: 639282:DEFDS_RS01300
uniprot id: D3PAZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

639282:DEFDS RS10195
gene id: 639282:DEFDS_RS10195
uniprot id: D3P9T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

639282:DEFDS RS08030
gene id: 639282:DEFDS_RS08030
uniprot id: D3P8L7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

639282:DEFDS RS04075
gene id: 639282:DEFDS_RS04075
uniprot id: D3PCG5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

639282:DEFDS RS04620
gene id: 639282:DEFDS_RS04620
uniprot id: D3PCR8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

639282:DEFDS RS03225
gene id: 639282:DEFDS_RS03225
uniprot id: D3PC04
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

639282:DEFDS RS02625
gene id: 639282:DEFDS_RS02625
uniprot id: D3PBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

639282:DEFDS RS06155
gene id: 639282:DEFDS_RS06155
uniprot id: D3PDL8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS09525
gene id: 639282:DEFDS_RS09525
uniprot id: D3P9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

639282:DEFDS RS05970
gene id: 639282:DEFDS_RS05970
uniprot id: D3PDI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

639282:DEFDS RS02355
gene id: 639282:DEFDS_RS02355
uniprot id: D3PBJ2
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS05895
gene id: 639282:DEFDS_RS05895
uniprot id: D3PDG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

639282:DEFDS RS00155
gene id: 639282:DEFDS_RS00155
uniprot id: D3PAC0
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS12395
gene id: 639282:DEFDS_RS12395
uniprot id: D3PF77
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

639282:DEFDS RS05100
gene id: 639282:DEFDS_RS05100
uniprot id: D3PD13
names: Similarity
messages: Belongs to the glutamate synthase family.

639282:DEFDS RS08185
gene id: 639282:DEFDS_RS08185
uniprot id: D3P8P7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

639282:DEFDS RS02000
gene id: 639282:DEFDS_RS02000
uniprot id: D3PBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

639282:DEFDS RS06175
gene id: 639282:DEFDS_RS06175
uniprot id: D3PDM2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

639282:DEFDS RS03120
gene id: 639282:DEFDS_RS03120
uniprot id: D3PBY3
names: Similarity
messages: Belongs to the GSP E family.

639282:DEFDS RS00660
gene id: 639282:DEFDS_RS00660
uniprot id: D3PAL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

639282:DEFDS RS06645
gene id: 639282:DEFDS_RS06645
uniprot id: D3PDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

639282:DEFDS RS09400
gene id: 639282:DEFDS_RS09400
uniprot id: D3P9C9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

639282:DEFDS RS10055
gene id: 639282:DEFDS_RS10055
uniprot id: D3P9Q3
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS02565
gene id: 639282:DEFDS_RS02565
uniprot id: D3PBN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS03035
gene id: 639282:DEFDS_RS03035
uniprot id: D3PBX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

639282:DEFDS RS05135
gene id: 639282:DEFDS_RS05135
uniprot id: D3PD20
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

639282:DEFDS RS00020
gene id: 639282:DEFDS_RS00020
uniprot id: D3PA93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

639282:DEFDS RS00630
gene id: 639282:DEFDS_RS00630
uniprot id: D3PAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

639282:DEFDS RS10430
gene id: 639282:DEFDS_RS10430
uniprot id: D3P9X7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

639282:DEFDS RS06570
gene id: 639282:DEFDS_RS06570
uniprot id: D3PDV1
names: Similarity
messages: Belongs to the GSP E family.

639282:DEFDS RS06765
gene id: 639282:DEFDS_RS06765
uniprot id: D3PDY4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

639282:DEFDS RS08510
gene id: 639282:DEFDS_RS08510
uniprot id: D3P8W0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

639282:DEFDS RS11590
gene id: 639282:DEFDS_RS11590
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS02945
gene id: 639282:DEFDS_RS02945
uniprot id: D3PBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

639282:DEFDS RS10060
gene id: 639282:DEFDS_RS10060
uniprot id: D3P9Q4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

639282:DEFDS RS10000
gene id: 639282:DEFDS_RS10000
uniprot id: D3P9P2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

639282:DEFDS RS06465
gene id: 639282:DEFDS_RS06465
uniprot id: D3PDT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS01200
gene id: 639282:DEFDS_RS01200
uniprot id: D3PAX2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

639282:DEFDS RS08650
gene id: 639282:DEFDS_RS08650
uniprot id: D3P8Y6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

639282:DEFDS RS08175
gene id: 639282:DEFDS_RS08175
uniprot id: D3P8P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

639282:DEFDS RS11490
gene id: 639282:DEFDS_RS11490
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS00785
gene id: 639282:DEFDS_RS00785
uniprot id: D3PAP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

639282:DEFDS RS01295
gene id: 639282:DEFDS_RS01295
uniprot id: D3PAY9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

639282:DEFDS RS10520
gene id: 639282:DEFDS_RS10520
uniprot id: D3P9Z4
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS06855
gene id: 639282:DEFDS_RS06855
uniprot id: D3PE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

639282:DEFDS RS00035
gene id: 639282:DEFDS_RS00035
uniprot id: D3PA96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

639282:DEFDS RS05185
gene id: 639282:DEFDS_RS05185
uniprot id: D3PD30
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

639282:DEFDS RS07165
gene id: 639282:DEFDS_RS07165
uniprot id: D3PE62
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

639282:DEFDS RS05810
gene id: 639282:DEFDS_RS05810
uniprot id: D3PDF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS04570
gene id: 639282:DEFDS_RS04570
uniprot id: D3PCQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

639282:DEFDS RS06460
gene id: 639282:DEFDS_RS06460
uniprot id: D3PDS9
names: Similarity
messages: Belongs to the DtxR/MntR family.

639282:DEFDS RS00780
gene id: 639282:DEFDS_RS00780
uniprot id: D3PAP3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

639282:DEFDS RS09175
gene id: 639282:DEFDS_RS09175
uniprot id: D3P985
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

639282:DEFDS RS07465
gene id: 639282:DEFDS_RS07465
uniprot id: D3PEC2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

639282:DEFDS RS04055
gene id: 639282:DEFDS_RS04055
uniprot id: D3PCG1
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS11955
gene id: 639282:DEFDS_RS11955
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS08145
gene id: 639282:DEFDS_RS08145
uniprot id: D3P8N9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

639282:DEFDS RS00575
gene id: 639282:DEFDS_RS00575
uniprot id: D3PAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS05030
gene id: 639282:DEFDS_RS05030
uniprot id: D3PCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS02145
gene id: 639282:DEFDS_RS02145
uniprot id: D3PBF0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

639282:DEFDS RS07340
gene id: 639282:DEFDS_RS07340
uniprot id: D3PE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

639282:DEFDS RS08240
gene id: 639282:DEFDS_RS08240
uniprot id: D3P8Q6
names: Similarity
messages: Belongs to the LarC family.

639282:DEFDS RS09545
gene id: 639282:DEFDS_RS09545
uniprot id: D3P9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

639282:DEFDS RS13100
gene id: 639282:DEFDS_RS13100
uniprot id: D3PCR5
names: Similarity
messages: Belongs to the class-I fumarase family.

639282:DEFDS RS00210
gene id: 639282:DEFDS_RS00210
uniprot id: D3PAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

639282:DEFDS RS04920
gene id: 639282:DEFDS_RS04920
uniprot id: D3PCX8
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS03875
gene id: 639282:DEFDS_RS03875
uniprot id: D3PCC6
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS07180
gene id: 639282:DEFDS_RS07180
uniprot id: D3PE65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

639282:DEFDS RS08935
gene id: 639282:DEFDS_RS08935
uniprot id: D3P942
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

639282:DEFDS RS09820
gene id: 639282:DEFDS_RS09820
uniprot id: D3P9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

639282:DEFDS RS02600
gene id: 639282:DEFDS_RS02600
uniprot id: D3PBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

639282:DEFDS RS03190
gene id: 639282:DEFDS_RS03190
uniprot id: D3PBZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

639282:DEFDS RS07635
gene id: 639282:DEFDS_RS07635
uniprot id: D3PEF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

639282:DEFDS RS06375
gene id: 639282:DEFDS_RS06375
uniprot id: D3PDR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

639282:DEFDS RS06865
gene id: 639282:DEFDS_RS06865
uniprot id: D3PE03
names: Similarity
messages: Belongs to the peptidase S41A family.

639282:DEFDS RS05120
gene id: 639282:DEFDS_RS05120
uniprot id: D3PD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

639282:DEFDS RS01030
gene id: 639282:DEFDS_RS01030
uniprot id: D3PAT9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

639282:DEFDS RS00040
gene id: 639282:DEFDS_RS00040
uniprot id: D3PA97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

639282:DEFDS RS00380
gene id: 639282:DEFDS_RS00380
uniprot id: D3PAG5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

639282:DEFDS RS09520
gene id: 639282:DEFDS_RS09520
uniprot id: D3P9E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

639282:DEFDS RS07745
gene id: 639282:DEFDS_RS07745
uniprot id: D3PEH8
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS03430
gene id: 639282:DEFDS_RS03430
uniprot id: D3PC41
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS01215
gene id: 639282:DEFDS_RS01215
uniprot id: D3PAX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

639282:DEFDS RS09475
gene id: 639282:DEFDS_RS09475
uniprot id: D3P9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

639282:DEFDS RS01105
gene id: 639282:DEFDS_RS01105
uniprot id: D3PAV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

639282:DEFDS RS08965
gene id: 639282:DEFDS_RS08965
uniprot id: D3P948
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

639282:DEFDS RS02670
gene id: 639282:DEFDS_RS02670
uniprot id: D3PBQ2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

639282:DEFDS RS06225
gene id: 639282:DEFDS_RS06225
uniprot id: D3PDN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS04955
gene id: 639282:DEFDS_RS04955
uniprot id: D3PCY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS06590
gene id: 639282:DEFDS_RS06590
uniprot id: D3PDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS05580
gene id: 639282:DEFDS_RS05580
uniprot id: D3PDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS04810
gene id: 639282:DEFDS_RS04810
uniprot id: D3PCV6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

639282:DEFDS RS06020
gene id: 639282:DEFDS_RS06020
uniprot id: D3PDJ0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

639282:DEFDS RS00500
gene id: 639282:DEFDS_RS00500
uniprot id: D3PAI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

639282:DEFDS RS00945
gene id: 639282:DEFDS_RS00945
uniprot id: D3PAS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS08600
gene id: 639282:DEFDS_RS08600
uniprot id: D3P8X7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

639282:DEFDS RS00930
gene id: 639282:DEFDS_RS00930
uniprot id: D3PAR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

639282:DEFDS RS10715
gene id: 639282:DEFDS_RS10715
uniprot id: D3PA31
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

639282:DEFDS RS00165
gene id: 639282:DEFDS_RS00165
uniprot id: D3PAC2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

639282:DEFDS RS09900
gene id: 639282:DEFDS_RS09900
uniprot id: D3P9M2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

639282:DEFDS RS10355
gene id: 639282:DEFDS_RS10355
uniprot id: D3P9W3
names: Similarity
messages: Belongs to the CobH/CbiC family.

639282:DEFDS RS00355
gene id: 639282:DEFDS_RS00355
uniprot id: D3PAG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS09835
gene id: 639282:DEFDS_RS09835
uniprot id: D3P9K9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS04095
gene id: 639282:DEFDS_RS04095
uniprot id: D3PCG9
names: Similarity
messages: Belongs to the citrate synthase family.

639282:DEFDS RS09735
gene id: 639282:DEFDS_RS09735
uniprot id: D3P9J0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

639282:DEFDS RS09535
gene id: 639282:DEFDS_RS09535
uniprot id: D3P9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

639282:DEFDS RS11340
gene id: 639282:DEFDS_RS11340
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS10070
gene id: 639282:DEFDS_RS10070
uniprot id: D3P9Q6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS02805
gene id: 639282:DEFDS_RS02805
uniprot id: D3PBS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS05815
gene id: 639282:DEFDS_RS05815
uniprot id: D3PDF3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

639282:DEFDS RS00220
gene id: 639282:DEFDS_RS00220
uniprot id: D3PAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

639282:DEFDS RS08925
gene id: 639282:DEFDS_RS08925
uniprot id: D3P940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

639282:DEFDS RS06675
gene id: 639282:DEFDS_RS06675
uniprot id: D3PDW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

639282:DEFDS RS04310
gene id: 639282:DEFDS_RS04310
uniprot id: D3PCL0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

639282:DEFDS RS02620
gene id: 639282:DEFDS_RS02620
uniprot id: D3PBP2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

639282:DEFDS RS08015
gene id: 639282:DEFDS_RS08015
uniprot id: D3P8L4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

639282:DEFDS RS00455
gene id: 639282:DEFDS_RS00455
uniprot id: D3PAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

639282:DEFDS RS09780
gene id: 639282:DEFDS_RS09780
uniprot id: D3P9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS05200
gene id: 639282:DEFDS_RS05200
uniprot id: D3PD33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

639282:DEFDS RS01090
gene id: 639282:DEFDS_RS01090
uniprot id: D3PAV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

639282:DEFDS RS04670
gene id: 639282:DEFDS_RS04670
uniprot id: D3PCS8
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS04705
gene id: 639282:DEFDS_RS04705
uniprot id: D3PCT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

639282:DEFDS RS09505
gene id: 639282:DEFDS_RS09505
uniprot id: D3P9E5
names: Similarity
messages: Belongs to the UPF0045 family.

639282:DEFDS RS05680
gene id: 639282:DEFDS_RS05680
uniprot id: D3PDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

639282:DEFDS RS11565
gene id: 639282:DEFDS_RS11565
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS09730
gene id: 639282:DEFDS_RS09730
uniprot id: D3P9I9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

639282:DEFDS RS04665
gene id: 639282:DEFDS_RS04665
uniprot id: D3PCS7
names: Similarity
messages: Belongs to the leucine-binding protein family.

639282:DEFDS RS03440
gene id: 639282:DEFDS_RS03440
uniprot id: D3PC43
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

639282:DEFDS RS03880
gene id: 639282:DEFDS_RS03880
uniprot id: D3PCC7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS02185
gene id: 639282:DEFDS_RS02185
uniprot id: D3PBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

639282:DEFDS RS11135
gene id: 639282:DEFDS_RS11135
uniprot id: D3PEK3
names: Similarity
messages: Belongs to the bacterial secretin family.

639282:DEFDS RS04240
gene id: 639282:DEFDS_RS04240
uniprot id: D3PCJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

639282:DEFDS RS08805
gene id: 639282:DEFDS_RS08805
uniprot id: D3P916
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

639282:DEFDS RS09425
gene id: 639282:DEFDS_RS09425
uniprot id: D3P9D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

639282:DEFDS RS01360
gene id: 639282:DEFDS_RS01360
uniprot id: D3PB02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

639282:DEFDS RS10105
gene id: 639282:DEFDS_RS10105
uniprot id: D3P9R3
names: Subcellular Location Annotation
messages: Cytoplasm

639282:DEFDS RS00180
gene id: 639282:DEFDS_RS00180
uniprot id: D3PAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

639282:DEFDS RS09970
gene id: 639282:DEFDS_RS09970
uniprot id: D3P9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

639282:DEFDS RS03840
gene id: 639282:DEFDS_RS03840
uniprot id: D3PCB9
names: Similarity
messages: Belongs to the AOR/FOR family.

639282:DEFDS RS01605
gene id: 639282:DEFDS_RS01605
uniprot id: D3PB46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS10960
gene id: 639282:DEFDS_RS10960
uniprot id: D3PA72
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

639282:DEFDS RS10905
gene id: 639282:DEFDS_RS10905
uniprot id: D3PA62
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

639282:DEFDS RS05475
gene id: 639282:DEFDS_RS05475
uniprot id: D3PD86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

639282:DEFDS RS00395
gene id: 639282:DEFDS_RS00395
uniprot id: D3PAG8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

639282:DEFDS RS04960
gene id: 639282:DEFDS_RS04960
uniprot id: D3PCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

639282:DEFDS RS04720
gene id: 639282:DEFDS_RS04720
uniprot id: D3PCT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

639282:DEFDS RS06875
gene id: 639282:DEFDS_RS06875
uniprot id: D3PE05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

639282:DEFDS RS05410
gene id: 639282:DEFDS_RS05410
uniprot id: D3PD73
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

639282:DEFDS RS00090
gene id: 639282:DEFDS_RS00090
uniprot id: D3PAA7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

639282:DEFDS RS08150
gene id: 639282:DEFDS_RS08150
uniprot id: D3P8P0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

639282:DEFDS RS10670
gene id: 639282:DEFDS_RS10670
uniprot id: D3PA24
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

639282:DEFDS RS03425
gene id: 639282:DEFDS_RS03425
uniprot id: D3PC40
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS05620
gene id: 639282:DEFDS_RS05620
uniprot id: D3PDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

639282:DEFDS RS01840
gene id: 639282:DEFDS_RS01840
uniprot id: D3PB88
names: Similarity
messages: Belongs to the polysaccharide synthase family.

639282:DEFDS RS00880
gene id: 639282:DEFDS_RS00880
uniprot id: D3PAR3
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

639282:DEFDS RS07480
gene id: 639282:DEFDS_RS07480
uniprot id: D3PEC4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

639282:DEFDS RS05480
gene id: 639282:DEFDS_RS05480
uniprot id: D3PD87
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

639282:DEFDS RS07210
gene id: 639282:DEFDS_RS07210
uniprot id: D3PE71
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

639282:DEFDS RS10400
gene id: 639282:DEFDS_RS10400
uniprot id: D3P9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS08140
gene id: 639282:DEFDS_RS08140
uniprot id: D3P8N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

639282:DEFDS RS06740
gene id: 639282:DEFDS_RS06740
uniprot id: D3PDY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

639282:DEFDS RS07625
gene id: 639282:DEFDS_RS07625
uniprot id: D3PEF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

639282:DEFDS RS07175
gene id: 639282:DEFDS_RS07175
uniprot id: D3PE64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

639282:DEFDS RS09555
gene id: 639282:DEFDS_RS09555
uniprot id: D3P9F5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

639282:DEFDS RS06500
gene id: 639282:DEFDS_RS06500
uniprot id: D3PDT7
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

639282:DEFDS RS00665
gene id: 639282:DEFDS_RS00665
uniprot id: D3PAM0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

639282:DEFDS RS07720
gene id: 639282:DEFDS_RS07720
uniprot id: D3PEH3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

639282:DEFDS RS02815
gene id: 639282:DEFDS_RS02815
uniprot id: D3PBS7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

639282:DEFDS RS11360
gene id: 639282:DEFDS_RS11360
uniprot id: D3PEP0
names: Similarity
messages: Belongs to the GSP E family.

639282:DEFDS RS07650
gene id: 639282:DEFDS_RS07650
uniprot id: D3PEF9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

639282:DEFDS RS01845
gene id: 639282:DEFDS_RS01845
uniprot id: D3PB89
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

639282:DEFDS RS08020
gene id: 639282:DEFDS_RS08020
uniprot id: D3P8L5
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS04225
gene id: 639282:DEFDS_RS04225
uniprot id: D3PCJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

639282:DEFDS RS04695
gene id: 639282:DEFDS_RS04695
uniprot id: D3PCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

639282:DEFDS RS06810
gene id: 639282:DEFDS_RS06810
uniprot id: D3PDZ3
names: Similarity
messages: Belongs to the pyruvate kinase family.

639282:DEFDS RS09430
gene id: 639282:DEFDS_RS09430
uniprot id: D3P9D5
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS09850
gene id: 639282:DEFDS_RS09850
uniprot id: D3P9L2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

639282:DEFDS RS08335
gene id: 639282:DEFDS_RS08335
uniprot id: D3P8S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

639282:DEFDS RS00775
gene id: 639282:DEFDS_RS00775
uniprot id: D3PAP2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

639282:DEFDS RS08860
gene id: 639282:DEFDS_RS08860
uniprot id: D3P927
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

639282:DEFDS RS01370
gene id: 639282:DEFDS_RS01370
uniprot id: D3PB04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

639282:DEFDS RS06435
gene id: 639282:DEFDS_RS06435
uniprot id: D3PDS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

639282:DEFDS RS06340
gene id: 639282:DEFDS_RS06340
uniprot id: D3PDQ5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

639282:DEFDS RS05210
gene id: 639282:DEFDS_RS05210
uniprot id: D3PD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

639282:DEFDS RS04915
gene id: 639282:DEFDS_RS04915
uniprot id: D3PCX7
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS01760
gene id: 639282:DEFDS_RS01760
uniprot id: D3PB77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

639282:DEFDS RS10515
gene id: 639282:DEFDS_RS10515
uniprot id: D3P9Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

639282:DEFDS RS01435
gene id: 639282:DEFDS_RS01435
uniprot id: D3PB15
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

639282:DEFDS RS09410
gene id: 639282:DEFDS_RS09410
uniprot id: D3P9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

639282:DEFDS RS00490
gene id: 639282:DEFDS_RS00490
uniprot id: D3PAI5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS07715
gene id: 639282:DEFDS_RS07715
uniprot id: D3PEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

639282:DEFDS RS01015
gene id: 639282:DEFDS_RS01015
uniprot id: D3PAT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

639282:DEFDS RS10450
gene id: 639282:DEFDS_RS10450
uniprot id: D3P9Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

639282:DEFDS RS02675
gene id: 639282:DEFDS_RS02675
uniprot id: D3PBQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

639282:DEFDS RS05440
gene id: 639282:DEFDS_RS05440
uniprot id: D3PD79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

639282:DEFDS RS05310
gene id: 639282:DEFDS_RS05310
uniprot id: D3PD54
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

639282:DEFDS RS06575
gene id: 639282:DEFDS_RS06575
uniprot id: D3PDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

639282:DEFDS RS02215
gene id: 639282:DEFDS_RS02215
uniprot id: D3PBG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

639282:DEFDS RS08930
gene id: 639282:DEFDS_RS08930
uniprot id: D3P941
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

639282:DEFDS RS08630
gene id: 639282:DEFDS_RS08630
uniprot id: D3P8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

639282:DEFDS RS07800
gene id: 639282:DEFDS_RS07800
uniprot id: D3P8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS02645
gene id: 639282:DEFDS_RS02645
uniprot id: D3PBP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS00670
gene id: 639282:DEFDS_RS00670
uniprot id: D3PAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS05390
gene id: 639282:DEFDS_RS05390
uniprot id: D3PD69
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

639282:DEFDS RS05965
gene id: 639282:DEFDS_RS05965
uniprot id: D3PDI1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

639282:DEFDS RS05885
gene id: 639282:DEFDS_RS05885
uniprot id: D3PDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

639282:DEFDS RS09570
gene id: 639282:DEFDS_RS09570
uniprot id: D3P9F8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

639282:DEFDS RS01225
gene id: 639282:DEFDS_RS01225
uniprot id: D3PAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

639282:DEFDS RS00005
gene id: 639282:DEFDS_RS00005
uniprot id: D3PA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

639282:DEFDS RS04875
gene id: 639282:DEFDS_RS04875
uniprot id: D3PCW9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS00890
gene id: 639282:DEFDS_RS00890
uniprot id: D3PAR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

639282:DEFDS RS10795
gene id: 639282:DEFDS_RS10795
uniprot id: D3PA47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

639282:DEFDS RS02380
gene id: 639282:DEFDS_RS02380
uniprot id: D3PBJ7
names: Similarity
messages: Belongs to the peptidase S24 family.

639282:DEFDS RS07640
gene id: 639282:DEFDS_RS07640
uniprot id: D3PEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

639282:DEFDS RS10065
gene id: 639282:DEFDS_RS10065
uniprot id: D3P9Q5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

639282:DEFDS RS08385
gene id: 639282:DEFDS_RS08385
uniprot id: D3P8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

639282:DEFDS RS09830
gene id: 639282:DEFDS_RS09830
uniprot id: D3P9K8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS10980
gene id: 639282:DEFDS_RS10980
uniprot id: D3PA76
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

639282:DEFDS RS08905
gene id: 639282:DEFDS_RS08905
uniprot id: D3P936
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

639282:DEFDS RS03710
gene id: 639282:DEFDS_RS03710
uniprot id: D3PC93
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

639282:DEFDS RS06945
gene id: 639282:DEFDS_RS06945
uniprot id: D3PE18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

639282:DEFDS RS06220
gene id: 639282:DEFDS_RS06220
uniprot id: D3PDN1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

639282:DEFDS RS02870
gene id: 639282:DEFDS_RS02870
uniprot id: D3PBT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

639282:DEFDS RS08350
gene id: 639282:DEFDS_RS08350
uniprot id: D3P8S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

639282:DEFDS RS04830
gene id: 639282:DEFDS_RS04830
uniprot id: D3PCW0
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS05570
gene id: 639282:DEFDS_RS05570
uniprot id: D3PDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

639282:DEFDS RS05025
gene id: 639282:DEFDS_RS05025
uniprot id: D3PCZ8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

639282:DEFDS RS08795
gene id: 639282:DEFDS_RS08795
uniprot id: D3P914
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

639282:DEFDS RS05670
gene id: 639282:DEFDS_RS05670
uniprot id: D3PDC5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

639282:DEFDS RS08345
gene id: 639282:DEFDS_RS08345
uniprot id: D3P8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

639282:DEFDS RS03650
gene id: 639282:DEFDS_RS03650
uniprot id: D3PC81
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

639282:DEFDS RS03705
gene id: 639282:DEFDS_RS03705
uniprot id: D3PC92
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

639282:DEFDS RS03310
gene id: 639282:DEFDS_RS03310
uniprot id: D3PC19
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS01210
gene id: 639282:DEFDS_RS01210
uniprot id: D3PAX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

639282:DEFDS RS09960
gene id: 639282:DEFDS_RS09960
uniprot id: D3P9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

639282:DEFDS RS09615
gene id: 639282:DEFDS_RS09615
uniprot id: D3P9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

639282:DEFDS RS07090
gene id: 639282:DEFDS_RS07090
uniprot id: D3PE46
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS08845
gene id: 639282:DEFDS_RS08845
uniprot id: D3P924
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

639282:DEFDS RS00305
gene id: 639282:DEFDS_RS00305
uniprot id: D3PAF0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

639282:DEFDS RS07850
gene id: 639282:DEFDS_RS07850
uniprot id: D3P8I1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS06260
gene id: 639282:DEFDS_RS06260
uniprot id: D3PDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

639282:DEFDS RS06210
gene id: 639282:DEFDS_RS06210
uniprot id: D3PDM9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

639282:DEFDS RS08850
gene id: 639282:DEFDS_RS08850
uniprot id: D3P925
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

639282:DEFDS RS00170
gene id: 639282:DEFDS_RS00170
uniprot id: D3PAC3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

639282:DEFDS RS01735
gene id: 639282:DEFDS_RS01735
uniprot id: D3PB72
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

639282:DEFDS RS07190
gene id: 639282:DEFDS_RS07190
uniprot id: D3PE67
names: Similarity
messages: Belongs to the band 7/mec-2 family.

639282:DEFDS RS05695
gene id: 639282:DEFDS_RS05695
uniprot id: D3PDD0
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS02730
gene id: 639282:DEFDS_RS02730
uniprot id: D3PBR0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

639282:DEFDS RS11855
gene id: 639282:DEFDS_RS11855
uniprot id: D3PEX5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

639282:DEFDS RS06410
gene id: 639282:DEFDS_RS06410
uniprot id: D3PDR9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

639282:DEFDS RS03655
gene id: 639282:DEFDS_RS03655
uniprot id: D3PC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS02375
gene id: 639282:DEFDS_RS02375
uniprot id: D3PBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

639282:DEFDS RS08195
gene id: 639282:DEFDS_RS08195
uniprot id: D3P8P9
names: Similarity
messages: Belongs to the proline racemase family.

639282:DEFDS RS09940
gene id: 639282:DEFDS_RS09940
uniprot id: D3P9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

639282:DEFDS RS07245
gene id: 639282:DEFDS_RS07245
uniprot id: D3PE78
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS08250
gene id: 639282:DEFDS_RS08250
uniprot id: D3P8Q8
names: Similarity
messages: Belongs to the UbiD family.

639282:DEFDS RS02590
gene id: 639282:DEFDS_RS02590
uniprot id: D3PBN6
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS07540
gene id: 639282:DEFDS_RS07540
uniprot id: D3PED6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

639282:DEFDS RS08120
gene id: 639282:DEFDS_RS08120
uniprot id: D3P8N4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS05720
gene id: 639282:DEFDS_RS05720
uniprot id: D3PDD5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

639282:DEFDS RS04950
gene id: 639282:DEFDS_RS04950
uniprot id: D3PCY4
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS06955
gene id: 639282:DEFDS_RS06955
uniprot id: D3PE20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

639282:DEFDS RS00755
gene id: 639282:DEFDS_RS00755
uniprot id: D3PAN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

639282:DEFDS RS06665
gene id: 639282:DEFDS_RS06665
uniprot id: D3PAY0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

639282:DEFDS RS08060
gene id: 639282:DEFDS_RS08060
uniprot id: D3P8M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

639282:DEFDS RS04700
gene id: 639282:DEFDS_RS04700
uniprot id: D3PCT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

639282:DEFDS RS08365
gene id: 639282:DEFDS_RS08365
uniprot id: D3P8T1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS01480
gene id: 639282:DEFDS_RS01480
uniprot id: D3PB23
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

639282:DEFDS RS08800
gene id: 639282:DEFDS_RS08800
uniprot id: D3P915
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

639282:DEFDS RS00480
gene id: 639282:DEFDS_RS00480
uniprot id: D3PAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

639282:DEFDS RS02020
gene id: 639282:DEFDS_RS02020
uniprot id: D3PBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

639282:DEFDS RS01040
gene id: 639282:DEFDS_RS01040
uniprot id: D3PAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

639282:DEFDS RS01900
gene id: 639282:DEFDS_RS01900
uniprot id: D3PBA0
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS06230
gene id: 639282:DEFDS_RS06230
uniprot id: D3PDN3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

639282:DEFDS RS02765
gene id: 639282:DEFDS_RS02765
uniprot id: D3PBR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

639282:DEFDS RS05915
gene id: 639282:DEFDS_RS05915
uniprot id: D3PDH3
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

639282:DEFDS RS04855
gene id: 639282:DEFDS_RS04855
uniprot id: D3PCW5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

639282:DEFDS RS10745
gene id: 639282:DEFDS_RS10745
uniprot id: D3PA37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

639282:DEFDS RS01325
gene id: 639282:DEFDS_RS01325
uniprot id: D3PAZ5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

639282:DEFDS RS05740
gene id: 639282:DEFDS_RS05740
uniprot id: D3PDD9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

639282:DEFDS RS07580
gene id: 639282:DEFDS_RS07580
uniprot id: D3PEE4
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS06425
gene id: 639282:DEFDS_RS06425
uniprot id: D3PDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

639282:DEFDS RS10120
gene id: 639282:DEFDS_RS10120
uniprot id: D3P9R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

639282:DEFDS RS12105
gene id: 639282:DEFDS_RS12105
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS02095
gene id: 639282:DEFDS_RS02095
uniprot id: D3PBE0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

639282:DEFDS RS04170
gene id: 639282:DEFDS_RS04170
uniprot id: D3PCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

639282:DEFDS RS07335
gene id: 639282:DEFDS_RS07335
uniprot id: D3PE96
names: Similarity
messages: Belongs to the archease family.

639282:DEFDS RS09540
gene id: 639282:DEFDS_RS09540
uniprot id: D3P9F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

639282:DEFDS RS06730
gene id: 639282:DEFDS_RS06730
uniprot id: D3PDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

639282:DEFDS RS05905
gene id: 639282:DEFDS_RS05905
uniprot id: D3PDH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

639282:DEFDS RS05605
gene id: 639282:DEFDS_RS05605
uniprot id: D3PDB2
names: Similarity
messages: Belongs to the peptidase U62 family.

639282:DEFDS RS10560
gene id: 639282:DEFDS_RS10560
uniprot id: D3PA02
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS09115
gene id: 639282:DEFDS_RS09115
uniprot id: D3P973
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

639282:DEFDS RS11090
gene id: 639282:DEFDS_RS11090
uniprot id: D3PEJ4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

639282:DEFDS RS02825
gene id: 639282:DEFDS_RS02825
uniprot id: D3PBS9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS02910
gene id: 639282:DEFDS_RS02910
uniprot id: D3PBU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

639282:DEFDS RS04735
gene id: 639282:DEFDS_RS04735
uniprot id: D3PCU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS09930
gene id: 639282:DEFDS_RS09930
uniprot id: D3P9M8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

639282:DEFDS RS02575
gene id: 639282:DEFDS_RS02575
uniprot id: D3PBN3
names: Similarity
messages: Belongs to the UPF0434 family.

639282:DEFDS RS11160
gene id: 639282:DEFDS_RS11160
uniprot id: D3PEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

639282:DEFDS RS10340
gene id: 639282:DEFDS_RS10340
uniprot id: D3P9W0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

639282:DEFDS RS00255
gene id: 639282:DEFDS_RS00255
uniprot id: D3PAE0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

639282:DEFDS RS09795
gene id: 639282:DEFDS_RS09795
uniprot id: D3P9K2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

639282:DEFDS RS06815
gene id: 639282:DEFDS_RS06815
uniprot id: D3PDZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

639282:DEFDS RS09245
gene id: 639282:DEFDS_RS09245
uniprot id: D3P999
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

639282:DEFDS RS01620
gene id: 639282:DEFDS_RS01620
uniprot id: D3PB49
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS00265
gene id: 639282:DEFDS_RS00265
uniprot id: D3PAE2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

639282:DEFDS RS07605
gene id: 639282:DEFDS_RS07605
uniprot id: D3PEF0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

639282:DEFDS RS01160
gene id: 639282:DEFDS_RS01160
uniprot id: D3PAW5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

639282:DEFDS RS05840
gene id: 639282:DEFDS_RS05840
uniprot id: D3PDF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

639282:DEFDS RS07610
gene id: 639282:DEFDS_RS07610
uniprot id: D3PEF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

639282:DEFDS RS07365
gene id: 639282:DEFDS_RS07365
uniprot id: D3PEA2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

639282:DEFDS RS10625
gene id: 639282:DEFDS_RS10625
uniprot id: D3PA15
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

639282:DEFDS RS12400
gene id: 639282:DEFDS_RS12400
uniprot id: D3PF78
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

639282:DEFDS RS07960
gene id: 639282:DEFDS_RS07960
uniprot id: D3P8K3
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS01085
gene id: 639282:DEFDS_RS01085
uniprot id: D3PAV0
names: Similarity
messages: Belongs to the UPF0235 family.

639282:DEFDS RS01390
gene id: 639282:DEFDS_RS01390
uniprot id: D3PB08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

639282:DEFDS RS04235
gene id: 639282:DEFDS_RS04235
uniprot id: D3PCJ5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

639282:DEFDS RS04065
gene id: 639282:DEFDS_RS04065
uniprot id: D3PCG3
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS10015
gene id: 639282:DEFDS_RS10015
uniprot id: D3P9P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

639282:DEFDS RS00405
gene id: 639282:DEFDS_RS00405
uniprot id: D3PAH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

639282:DEFDS RS07030
gene id: 639282:DEFDS_RS07030
uniprot id: D3PE34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

639282:DEFDS RS11285
gene id: 639282:DEFDS_RS11285
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS00760
gene id: 639282:DEFDS_RS00760
uniprot id: D3PAN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

639282:DEFDS RS02315
gene id: 639282:DEFDS_RS02315
uniprot id: D3PBI4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

639282:DEFDS RS04725
gene id: 639282:DEFDS_RS04725
uniprot id: D3PCT9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS08830
gene id: 639282:DEFDS_RS08830
uniprot id: D3P921
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

639282:DEFDS RS10640
gene id: 639282:DEFDS_RS10640
uniprot id: D3PA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

639282:DEFDS RS07775
gene id: 639282:DEFDS_RS07775
uniprot id: D3PEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

639282:DEFDS RS09635
gene id: 639282:DEFDS_RS09635
uniprot id: D3P9H1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

639282:DEFDS RS00030
gene id: 639282:DEFDS_RS00030
uniprot id: D3PA95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS03240
gene id: 639282:DEFDS_RS03240
uniprot id: D3PC07
names: Similarity
messages: Belongs to the RutC family.

639282:DEFDS RS10710
gene id: 639282:DEFDS_RS10710
uniprot id: D3PA30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

639282:DEFDS RS09840
gene id: 639282:DEFDS_RS09840
uniprot id: D3P9L0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

639282:DEFDS RS03480
gene id: 639282:DEFDS_RS03480
uniprot id: D3PC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS10335
gene id: 639282:DEFDS_RS10335
uniprot id: D3P9V9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

639282:DEFDS RS00345
gene id: 639282:DEFDS_RS00345
uniprot id: D3PAF8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

639282:DEFDS RS11845
gene id: 639282:DEFDS_RS11845
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS00540
gene id: 639282:DEFDS_RS00540
uniprot id: D3PAJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

639282:DEFDS RS09910
gene id: 639282:DEFDS_RS09910
uniprot id: D3P9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

639282:DEFDS RS07005
gene id: 639282:DEFDS_RS07005
uniprot id: D3PE29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

639282:DEFDS RS06345
gene id: 639282:DEFDS_RS06345
uniprot id: D3PDQ6
names: Subcellular Location Annotation
messages: Mitochondrion

639282:DEFDS RS09445
gene id: 639282:DEFDS_RS09445
uniprot id: D3P9D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

639282:DEFDS RS01075
gene id: 639282:DEFDS_RS01075
uniprot id: D3PAU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

639282:DEFDS RS10230
gene id: 639282:DEFDS_RS10230
uniprot id: D3P9T8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

639282:DEFDS RS09585
gene id: 639282:DEFDS_RS09585
uniprot id: D3P9G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

639282:DEFDS RS02210
gene id: 639282:DEFDS_RS02210
uniprot id: D3PBG3
names: Similarity
messages: Belongs to the TrpF family.

639282:DEFDS RS04880
gene id: 639282:DEFDS_RS04880
uniprot id: D3PCX0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

639282:DEFDS RS02880
gene id: 639282:DEFDS_RS02880
uniprot id: D3PBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

639282:DEFDS RS10095
gene id: 639282:DEFDS_RS10095
uniprot id: D3P9R1
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS05425
gene id: 639282:DEFDS_RS05425
uniprot id: D3PD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

639282:DEFDS RS10465
gene id: 639282:DEFDS_RS10465
uniprot id: D3P9Y4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

639282:DEFDS RS05175
gene id: 639282:DEFDS_RS05175
uniprot id: D3PD28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

639282:DEFDS RS00825
gene id: 639282:DEFDS_RS00825
uniprot id: D3PAQ2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

639282:DEFDS RS11040
gene id: 639282:DEFDS_RS11040
uniprot id: D3PA88
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

639282:DEFDS RS08210
gene id: 639282:DEFDS_RS08210
uniprot id: D3P8Q2
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

639282:DEFDS RS02840
gene id: 639282:DEFDS_RS02840
uniprot id: D3PBT2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

639282:DEFDS RS12815
gene id: 639282:DEFDS_RS12815
uniprot id: D3PF41
names: Similarity
messages: Belongs to the ParB family.

639282:DEFDS RS08725
gene id: 639282:DEFDS_RS08725
uniprot id: D3P900
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

639282:DEFDS RS02720
gene id: 639282:DEFDS_RS02720
uniprot id: D3PBQ8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

639282:DEFDS RS10115
gene id: 639282:DEFDS_RS10115
uniprot id: D3P9R5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

639282:DEFDS RS01265
gene id: 639282:DEFDS_RS01265
uniprot id: D3PAY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

639282:DEFDS RS00940
gene id: 639282:DEFDS_RS00940
uniprot id: D3PAS1
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

639282:DEFDS RS01710
gene id: 639282:DEFDS_RS01710
uniprot id: D3PB67
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

639282:DEFDS RS10750
gene id: 639282:DEFDS_RS10750
uniprot id: D3PA38
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

639282:DEFDS RS05245
gene id: 639282:DEFDS_RS05245
uniprot id: D3PD42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

639282:DEFDS RS12080
gene id: 639282:DEFDS_RS12080
uniprot id: D3PF15
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS04860
gene id: 639282:DEFDS_RS04860
uniprot id: D3PCW6
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

639282:DEFDS RS08115
gene id: 639282:DEFDS_RS08115
uniprot id: D3P8N3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

639282:DEFDS RS02060
gene id: 639282:DEFDS_RS02060
uniprot id: D3PBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

639282:DEFDS RS07355
gene id: 639282:DEFDS_RS07355
uniprot id: D3PEA0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

639282:DEFDS RS10420
gene id: 639282:DEFDS_RS10420
uniprot id: D3P9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

639282:DEFDS RS10855
gene id: 639282:DEFDS_RS10855
uniprot id: D3PA52
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

639282:DEFDS RS00235
gene id: 639282:DEFDS_RS00235
uniprot id: D3PAD6
names: Similarity
messages: Belongs to the RecJ family.

639282:DEFDS RS10575
gene id: 639282:DEFDS_RS10575
uniprot id: D3PA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

639282:DEFDS RS11155
gene id: 639282:DEFDS_RS11155
uniprot id: D3PEK7
names: Similarity
messages: Belongs to the GSP E family.

639282:DEFDS RS09230
gene id: 639282:DEFDS_RS09230
uniprot id: D3P996
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

639282:DEFDS RS04610
gene id: 639282:DEFDS_RS04610
uniprot id: D3PCR6
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

639282:DEFDS RS10030
gene id: 639282:DEFDS_RS10030
uniprot id: D3P9P8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

639282:DEFDS RS09955
gene id: 639282:DEFDS_RS09955
uniprot id: D3P9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

639282:DEFDS RS05430
gene id: 639282:DEFDS_RS05430
uniprot id: D3PD77
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS09290
gene id: 639282:DEFDS_RS09290
uniprot id: D3P9A8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

639282:DEFDS RS12040
gene id: 639282:DEFDS_RS12040
uniprot id: D3PF08
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

639282:DEFDS RS08610
gene id: 639282:DEFDS_RS08610
uniprot id: D3P8X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

639282:DEFDS RS01205
gene id: 639282:DEFDS_RS01205
uniprot id: D3PAX3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

639282:DEFDS RS07345
gene id: 639282:DEFDS_RS07345
uniprot id: D3PE98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS10875
gene id: 639282:DEFDS_RS10875
uniprot id: D3PA56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

639282:DEFDS RS10365
gene id: 639282:DEFDS_RS10365
uniprot id: D3P9W5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

639282:DEFDS RS11060
gene id: 639282:DEFDS_RS11060
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS02365
gene id: 639282:DEFDS_RS02365
uniprot id: D3PBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

639282:DEFDS RS02400
gene id: 639282:DEFDS_RS02400
uniprot id: D3PBK0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

639282:DEFDS RS00290
gene id: 639282:DEFDS_RS00290
uniprot id: D3PAE7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

639282:DEFDS RS09530
gene id: 639282:DEFDS_RS09530
uniprot id: D3P9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

639282:DEFDS RS08895
gene id: 639282:DEFDS_RS08895
uniprot id: D3P934
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

639282:DEFDS RS07475
gene id: 639282:DEFDS_RS07475
uniprot id: D3PEC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

639282:DEFDS RS12725
gene id: 639282:DEFDS_RS12725
uniprot id: D3P9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

639282:DEFDS RS04215
gene id: 639282:DEFDS_RS04215
uniprot id: D3PCJ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

639282:DEFDS RS02320
gene id: 639282:DEFDS_RS02320
uniprot id: D3PBI5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

639282:DEFDS RS07215
gene id: 639282:DEFDS_RS07215
uniprot id: D3PE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

639282:DEFDS RS05920
gene id: 639282:DEFDS_RS05920
uniprot id: D3PDH4
names: Similarity
messages: Belongs to the aspartokinase family.

639282:DEFDS RS12570
gene id: 639282:DEFDS_RS12570
uniprot id: D3PCF1
names: Similarity
messages: Belongs to the peptidase S8 family.

639282:DEFDS RS08890
gene id: 639282:DEFDS_RS08890
uniprot id: D3P933
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

639282:DEFDS RS11800
gene id: 639282:DEFDS_RS11800
uniprot id: D3PEW6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

639282:DEFDS RS06935
gene id: 639282:DEFDS_RS06935
uniprot id: D3PE16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

639282:DEFDS RS03020
gene id: 639282:DEFDS_RS03020
uniprot id: D3PBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

639282:DEFDS RS06355
gene id: 639282:DEFDS_RS06355
uniprot id: D3PDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

639282:DEFDS RS06065
gene id: 639282:DEFDS_RS06065
uniprot id: D3PDJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS00175
gene id: 639282:DEFDS_RS00175
uniprot id: D3PAC4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

639282:DEFDS RS09260
gene id: 639282:DEFDS_RS09260
uniprot id: D3P9A2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

639282:DEFDS RS05500
gene id: 639282:DEFDS_RS05500
uniprot id: D3PD91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

639282:DEFDS RS02220
gene id: 639282:DEFDS_RS02220
uniprot id: D3PBG5
names: Similarity
messages: Belongs to the TrpA family.

639282:DEFDS RS10995
gene id: 639282:DEFDS_RS10995
uniprot id: D3PA79
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

639282:DEFDS RS05900
gene id: 639282:DEFDS_RS05900
uniprot id: D3PDH0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

639282:DEFDS RS02115
gene id: 639282:DEFDS_RS02115
uniprot id: D3PBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

639282:DEFDS RS07385
gene id: 639282:DEFDS_RS07385
uniprot id: D3PEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

639282:DEFDS RS12175
gene id: 639282:DEFDS_RS12175
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS07935
gene id: 639282:DEFDS_RS07935
uniprot id: D3P8J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

639282:DEFDS RS04675
gene id: 639282:DEFDS_RS04675
uniprot id: D3PCS9
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS05060
gene id: 639282:DEFDS_RS05060
uniprot id: D3PD05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS02245
gene id: 639282:DEFDS_RS02245
uniprot id: D3PBH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

639282:DEFDS RS09090
gene id: 639282:DEFDS_RS09090
uniprot id: D3P968
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

639282:DEFDS RS02640
gene id: 639282:DEFDS_RS02640
uniprot id: D3PBP6
names: Subcellular Location Annotation
messages: Cytoplasm

639282:DEFDS RS08575
gene id: 639282:DEFDS_RS08575
uniprot id: D3P8X2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

639282:DEFDS RS08960
gene id: 639282:DEFDS_RS08960
uniprot id: D3P947
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

639282:DEFDS RS12005
gene id: 639282:DEFDS_RS12005
uniprot id: D3PF01
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

639282:DEFDS RS02370
gene id: 639282:DEFDS_RS02370
uniprot id: D3PBJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.

639282:DEFDS RS01610
gene id: 639282:DEFDS_RS01610
uniprot id: D3PB47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

639282:DEFDS RS08990
gene id: 639282:DEFDS_RS08990
uniprot id: D3P939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

639282:DEFDS RS10780
gene id: 639282:DEFDS_RS10780
uniprot id: D3PA44
names: Similarity
messages: Belongs to the glutamate synthase family.

639282:DEFDS RS10380
gene id: 639282:DEFDS_RS10380
uniprot id: D3P9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

639282:DEFDS RS08525
gene id: 639282:DEFDS_RS08525
uniprot id: D3P8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

639282:DEFDS RS03900
gene id: 639282:DEFDS_RS03900
uniprot id: D3PCD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

639282:DEFDS RS05115
gene id: 639282:DEFDS_RS05115
uniprot id: D3PD16
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

639282:DEFDS RS00450
gene id: 639282:DEFDS_RS00450
uniprot id: D3PAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

639282:DEFDS RS10535
gene id: 639282:DEFDS_RS10535
uniprot id: D3P9Z7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

639282:DEFDS RS08825
gene id: 639282:DEFDS_RS08825
uniprot id: D3P920
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

639282:DEFDS RS00625
gene id: 639282:DEFDS_RS00625
uniprot id: D3PAL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS05850
gene id: 639282:DEFDS_RS05850
uniprot id: D3PDG0
names: Similarity
messages: Belongs to the Fur family.

639282:DEFDS RS02050
gene id: 639282:DEFDS_RS02050
uniprot id: D3PBD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

639282:DEFDS RS05980
gene id: 639282:DEFDS_RS05980
uniprot id: D3PDI4
names: Similarity
messages: Belongs to the GARS family.

639282:DEFDS RS05890
gene id: 639282:DEFDS_RS05890
uniprot id: D3PDG8
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

639282:DEFDS RS03630
gene id: 639282:DEFDS_RS03630
uniprot id: D3PC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

639282:DEFDS RS05540
gene id: 639282:DEFDS_RS05540
uniprot id: D3PD99
names: Similarity
messages: Belongs to the peptidase U62 family.

639282:DEFDS RS05875
gene id: 639282:DEFDS_RS05875
uniprot id: D3PDG5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

639282:DEFDS RS02605
gene id: 639282:DEFDS_RS02605
uniprot id: D3PBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

639282:DEFDS RS07710
gene id: 639282:DEFDS_RS07710
uniprot id: D3PEH1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

639282:DEFDS RS08135
gene id: 639282:DEFDS_RS08135
uniprot id: D3P8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

639282:DEFDS RS02065
gene id: 639282:DEFDS_RS02065
uniprot id: D3PBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

639282:DEFDS RS02770
gene id: 639282:DEFDS_RS02770
uniprot id: D3PBR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

639282:DEFDS RS03415
gene id: 639282:DEFDS_RS03415
uniprot id: D3PC38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS09965
gene id: 639282:DEFDS_RS09965
uniprot id: D3P9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

639282:DEFDS RS02420
gene id: 639282:DEFDS_RS02420
uniprot id: D3PBK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

639282:DEFDS RS09610
gene id: 639282:DEFDS_RS09610
uniprot id: D3P9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

639282:DEFDS RS10595
gene id: 639282:DEFDS_RS10595
uniprot id: D3PA09
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

639282:DEFDS RS00965
gene id: 639282:DEFDS_RS00965
uniprot id: D3PAS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

639282:DEFDS RS03295
gene id: 639282:DEFDS_RS03295
uniprot id: D3PC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

639282:DEFDS RS01000
gene id: 639282:DEFDS_RS01000
uniprot id: D3PAT3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

639282:DEFDS RS05255
gene id: 639282:DEFDS_RS05255
uniprot id: D3PD44
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

639282:DEFDS RS04765
gene id: 639282:DEFDS_RS04765
uniprot id: D3PCU7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

639282:DEFDS RS04615
gene id: 639282:DEFDS_RS04615
uniprot id: D3PCR7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

639282:DEFDS RS06330
gene id: 639282:DEFDS_RS06330
uniprot id: D3PDQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS07140
gene id: 639282:DEFDS_RS07140
uniprot id: D3PE56
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS10865
gene id: 639282:DEFDS_RS10865
uniprot id: D3PA54
names: Similarity
messages: Belongs to the FlgM family.

639282:DEFDS RS00465
gene id: 639282:DEFDS_RS00465
uniprot id: D3PAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

639282:DEFDS RS09765
gene id: 639282:DEFDS_RS09765
uniprot id: D3P9J6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

639282:DEFDS RS10435
gene id: 639282:DEFDS_RS10435
uniprot id: D3P9X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

639282:DEFDS RS11240
gene id: 639282:DEFDS_RS11240
uniprot id: D3PEI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

639282:DEFDS RS00510
gene id: 639282:DEFDS_RS00510
uniprot id: D3PAI9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

639282:DEFDS RS11430
gene id: 639282:DEFDS_RS11430
uniprot id: D3PEQ4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

639282:DEFDS RS02915
gene id: 639282:DEFDS_RS02915
uniprot id: D3PBU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

639282:DEFDS RS12825
gene id: 639282:DEFDS_RS12825
uniprot id: D3PAY0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

639282:DEFDS RS08855
gene id: 639282:DEFDS_RS08855
uniprot id: D3P926
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

639282:DEFDS RS08035
gene id: 639282:DEFDS_RS08035
uniprot id: D3P8L8
names: Similarity
messages: Belongs to the SfsA family.

639282:DEFDS RS09860
gene id: 639282:DEFDS_RS09860
uniprot id: D3P9L4
names: Similarity
messages: Belongs to the ribF family.

639282:DEFDS RS04080
gene id: 639282:DEFDS_RS04080
uniprot id: D3PCG6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

639282:DEFDS RS09825
gene id: 639282:DEFDS_RS09825
uniprot id: D3P9K7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS01065
gene id: 639282:DEFDS_RS01065
uniprot id: D3PAU6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

639282:DEFDS RS10720
gene id: 639282:DEFDS_RS10720
uniprot id: D3PA32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

639282:DEFDS RS02425
gene id: 639282:DEFDS_RS02425
uniprot id: D3PBK5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

639282:DEFDS RS05270
gene id: 639282:DEFDS_RS05270
uniprot id: D3PD47
names: Subcellular Location Annotation
messages: Cytoplasm

639282:DEFDS RS06320
gene id: 639282:DEFDS_RS06320
uniprot id: D3PDQ1
names: Similarity
messages: Belongs to the GSP E family.

639282:DEFDS RS02435
gene id: 639282:DEFDS_RS02435
uniprot id: D3PBK7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

639282:DEFDS RS03945
gene id: 639282:DEFDS_RS03945
uniprot id: D3PCE0
names: Similarity
messages: Belongs to the UPF0597 family.

639282:DEFDS RS09600
gene id: 639282:DEFDS_RS09600
uniprot id: D3P9G4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

639282:DEFDS RS04305
gene id: 639282:DEFDS_RS04305
uniprot id: D3PCK9
names: Similarity
messages: Belongs to the UPF0047 family.

639282:DEFDS RS12795
gene id: 639282:DEFDS_RS12795
uniprot id: D3PEZ4
names: Similarity
messages: Belongs to the peptidase S8 family.

639282:DEFDS RS06315
gene id: 639282:DEFDS_RS06315
uniprot id: D3PDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

639282:DEFDS RS02300
gene id: 639282:DEFDS_RS02300
uniprot id: D3PBI1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

639282:DEFDS RS09975
gene id: 639282:DEFDS_RS09975
uniprot id: D3P9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

639282:DEFDS RS06160
gene id: 639282:DEFDS_RS06160
uniprot id: D3PDL9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

639282:DEFDS RS04870
gene id: 639282:DEFDS_RS04870
uniprot id: D3PCW8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

639282:DEFDS RS10665
gene id: 639282:DEFDS_RS10665
uniprot id: D3PA23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

639282:DEFDS RS05010
gene id: 639282:DEFDS_RS05010
uniprot id: D3PCZ5
names: Similarity
messages: Belongs to the YggT family.

639282:DEFDS RS02580
gene id: 639282:DEFDS_RS02580
uniprot id: D3PBN4
names: Subcellular Location Annotation
messages: Membrane

639282:DEFDS RS10910
gene id: 639282:DEFDS_RS10910
uniprot id: D3PA63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

639282:DEFDS RS09715
gene id: 639282:DEFDS_RS09715
uniprot id: D3P9I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

639282:DEFDS RS02930
gene id: 639282:DEFDS_RS02930
uniprot id: D3PBV0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

639282:DEFDS RS09015
gene id: 639282:DEFDS_RS09015
uniprot id: D3P953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

639282:DEFDS RS09040
gene id: 639282:DEFDS_RS09040
uniprot id: D3P958
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

639282:DEFDS RS08915
gene id: 639282:DEFDS_RS08915
uniprot id: D3P938
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

639282:DEFDS RS02610
gene id: 639282:DEFDS_RS02610
uniprot id: D3PBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

639282:DEFDS RS08835
gene id: 639282:DEFDS_RS08835
uniprot id: D3P922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

639282:DEFDS RS08865
gene id: 639282:DEFDS_RS08865
uniprot id: D3P928
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.