632518:CALOW RS10085
gene id: 632518:CALOW_RS10085
uniprot id: E4Q5V9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS03750
gene id: 632518:CALOW_RS03750
uniprot id: E4Q5M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS05200
gene id: 632518:CALOW_RS05200
uniprot id: E4Q142
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

632518:CALOW RS07090
gene id: 632518:CALOW_RS07090
uniprot id: E4Q2U4
names: Similarity
messages: Belongs to the bacterial flagellin family.

632518:CALOW RS04405
gene id: 632518:CALOW_RS04405
uniprot id: E4Q6E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS05950
gene id: 632518:CALOW_RS05950
uniprot id: E4Q1L3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

632518:CALOW RS08835
gene id: 632518:CALOW_RS08835
uniprot id: E4Q4L0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

632518:CALOW RS08370
gene id: 632518:CALOW_RS08370
uniprot id: E4Q455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS00620
gene id: 632518:CALOW_RS00620
uniprot id: E4Q2A4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632518:CALOW RS04635
gene id: 632518:CALOW_RS04635
uniprot id: E4Q6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS03965
gene id: 632518:CALOW_RS03965
uniprot id: E4Q254
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS03110
gene id: 632518:CALOW_RS03110
uniprot id: E4Q528
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

632518:CALOW RS08195
gene id: 632518:CALOW_RS08195
uniprot id: E4Q421
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

632518:CALOW RS07380
gene id: 632518:CALOW_RS07380
uniprot id: E4Q2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

632518:CALOW RS08510
gene id: 632518:CALOW_RS08510
uniprot id: E4Q481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

632518:CALOW RS04755
gene id: 632518:CALOW_RS04755
uniprot id: E4Q6T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

632518:CALOW RS02705
gene id: 632518:CALOW_RS02705
uniprot id: E4Q4G3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

632518:CALOW RS05480
gene id: 632518:CALOW_RS05480
uniprot id: E4Q1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

632518:CALOW RS07315
gene id: 632518:CALOW_RS07315
uniprot id: E4Q2Y2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

632518:CALOW RS05635
gene id: 632518:CALOW_RS05635
uniprot id: E4Q1F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS09675
gene id: 632518:CALOW_RS09675
uniprot id: E4Q5G1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS00015
gene id: 632518:CALOW_RS00015
uniprot id: E4Q1S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

632518:CALOW RS06285
gene id: 632518:CALOW_RS06285
uniprot id: E4Q1Z6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

632518:CALOW RS06195
gene id: 632518:CALOW_RS06195
uniprot id: E4Q1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

632518:CALOW RS06170
gene id: 632518:CALOW_RS06170
uniprot id: E4Q1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

632518:CALOW RS06965
gene id: 632518:CALOW_RS06965
uniprot id: E4Q2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

632518:CALOW RS04970
gene id: 632518:CALOW_RS04970
uniprot id: E4Q6X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS05890
gene id: 632518:CALOW_RS05890
uniprot id: E4Q1K1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632518:CALOW RS06160
gene id: 632518:CALOW_RS06160
uniprot id: E4Q1Q5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

632518:CALOW RS06120
gene id: 632518:CALOW_RS06120
uniprot id: E4Q1P7
names: Similarity
messages: Belongs to the GARS family.

632518:CALOW RS05120
gene id: 632518:CALOW_RS05120
uniprot id: E4Q126
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

632518:CALOW RS06365
gene id: 632518:CALOW_RS06365
uniprot id: E4Q212
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

632518:CALOW RS05715
gene id: 632518:CALOW_RS05715
uniprot id: E4Q1G9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

632518:CALOW RS07700
gene id: 632518:CALOW_RS07700
uniprot id: E4Q3C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

632518:CALOW RS03290
gene id: 632518:CALOW_RS03290
uniprot id: E4Q564
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

632518:CALOW RS02945
gene id: 632518:CALOW_RS02945
uniprot id: E4Q4S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

632518:CALOW RS07245
gene id: 632518:CALOW_RS07245
uniprot id: E4Q2X3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

632518:CALOW RS10110
gene id: 632518:CALOW_RS10110
uniprot id: E4Q5W4
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632518:CALOW RS02600
gene id: 632518:CALOW_RS02600
uniprot id: E4Q4E2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

632518:CALOW RS04555
gene id: 632518:CALOW_RS04555
uniprot id: E4Q6H6
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

632518:CALOW RS07790
gene id: 632518:CALOW_RS07790
uniprot id: E4Q3E4
names: Similarity
messages: Belongs to the CdaR family.

632518:CALOW RS09335
gene id: 632518:CALOW_RS09335
uniprot id: E4Q523
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

632518:CALOW RS06685
gene id: 632518:CALOW_RS06685
uniprot id: E4Q2E4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

632518:CALOW RS07520
gene id: 632518:CALOW_RS07520
uniprot id: E4Q391
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS01680
gene id: 632518:CALOW_RS01680
uniprot id: E4Q3G6
names: Similarity
messages: Belongs to the glycosyl hydrolase.

632518:CALOW RS11810
gene id: 632518:CALOW_RS11810
uniprot id: E4Q1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

632518:CALOW RS03355
gene id: 632518:CALOW_RS03355
uniprot id: E4Q577
names: Similarity
messages: Belongs to the AOR/FOR family.

632518:CALOW RS10105
gene id: 632518:CALOW_RS10105
uniprot id: E4Q5W3
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS03175
gene id: 632518:CALOW_RS03175
uniprot id: E4Q541
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

632518:CALOW RS06430
gene id: 632518:CALOW_RS06430
uniprot id: E4Q225
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

632518:CALOW RS06570
gene id: 632518:CALOW_RS06570
uniprot id: E4Q248
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

632518:CALOW RS02540
gene id: 632518:CALOW_RS02540
uniprot id: E4Q4D0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

632518:CALOW RS07890
gene id: 632518:CALOW_RS07890
uniprot id: E4Q3N3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

632518:CALOW RS06360
gene id: 632518:CALOW_RS06360
uniprot id: E4Q211
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

632518:CALOW RS00125
gene id: 632518:CALOW_RS00125
uniprot id: E4Q1U4
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS06065
gene id: 632518:CALOW_RS06065
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS06090
gene id: 632518:CALOW_RS06090
uniprot id: E4Q1P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

632518:CALOW RS08890
gene id: 632518:CALOW_RS08890
uniprot id: E4Q4L9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

632518:CALOW RS05750
gene id: 632518:CALOW_RS05750
uniprot id: E4Q1H3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

632518:CALOW RS10420
gene id: 632518:CALOW_RS10420
uniprot id: E4Q694
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS05170
gene id: 632518:CALOW_RS05170
uniprot id: E4Q136
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS06310
gene id: 632518:CALOW_RS06310
uniprot id: E4Q201
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

632518:CALOW RS02065
gene id: 632518:CALOW_RS02065
uniprot id: E4Q3W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

632518:CALOW RS10775
gene id: 632518:CALOW_RS10775
uniprot id: E4Q6P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS04675
gene id: 632518:CALOW_RS04675
uniprot id: E4Q6J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

632518:CALOW RS01230
gene id: 632518:CALOW_RS01230
uniprot id: E4Q314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

632518:CALOW RS07810
gene id: 632518:CALOW_RS07810
uniprot id: E4Q3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

632518:CALOW RS11190
gene id: 632518:CALOW_RS11190
uniprot id: E4Q737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

632518:CALOW RS08225
gene id: 632518:CALOW_RS08225
uniprot id: E4Q427
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

632518:CALOW RS03040
gene id: 632518:CALOW_RS03040
uniprot id: E4Q4T9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

632518:CALOW RS06680
gene id: 632518:CALOW_RS06680
uniprot id: E4Q2E3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

632518:CALOW RS08805
gene id: 632518:CALOW_RS08805
uniprot id: E4Q4K3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

632518:CALOW RS02050
gene id: 632518:CALOW_RS02050
uniprot id: E4Q3W1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

632518:CALOW RS09460
gene id: 632518:CALOW_RS09460
uniprot id: E4Q5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS05285
gene id: 632518:CALOW_RS05285
uniprot id: E4Q158
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

632518:CALOW RS07130
gene id: 632518:CALOW_RS07130
uniprot id: E4Q2V2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

632518:CALOW RS10425
gene id: 632518:CALOW_RS10425
uniprot id: E4Q695
names: Similarity
messages: Belongs to the peptidase S41A family.

632518:CALOW RS07160
gene id: 632518:CALOW_RS07160
uniprot id: E4Q2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

632518:CALOW RS11430
gene id: 632518:CALOW_RS11430
uniprot id: E4Q1B5
names: Similarity
messages: Belongs to the GerABKA family.

632518:CALOW RS05670
gene id: 632518:CALOW_RS05670
uniprot id: E4Q1G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

632518:CALOW RS05965
gene id: 632518:CALOW_RS05965
uniprot id: E4Q1L6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632518:CALOW RS08525
gene id: 632518:CALOW_RS08525
uniprot id: E4Q484
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

632518:CALOW RS08470
gene id: 632518:CALOW_RS08470
uniprot id: E4Q475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

632518:CALOW RS05910
gene id: 632518:CALOW_RS05910
uniprot id: E4Q1K5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

632518:CALOW RS10780
gene id: 632518:CALOW_RS10780
uniprot id: E4Q6P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS04520
gene id: 632518:CALOW_RS04520
uniprot id: E4Q6G9
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS05345
gene id: 632518:CALOW_RS05345
uniprot id: E4Q170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

632518:CALOW RS06695
gene id: 632518:CALOW_RS06695
uniprot id: E4Q2E6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

632518:CALOW RS10865
gene id: 632518:CALOW_RS10865
uniprot id: E4Q6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS11105
gene id: 632518:CALOW_RS11105
uniprot id: E4Q721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS00550
gene id: 632518:CALOW_RS00550
uniprot id: E4Q290
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

632518:CALOW RS00540
gene id: 632518:CALOW_RS00540
uniprot id: E4Q288
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS04870
gene id: 632518:CALOW_RS04870
uniprot id: E4Q6V4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

632518:CALOW RS07370
gene id: 632518:CALOW_RS07370
uniprot id: E4Q2Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

632518:CALOW RS06165
gene id: 632518:CALOW_RS06165
uniprot id: E4Q1Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01065
gene id: 632518:CALOW_RS01065
uniprot id: E4Q2R5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

632518:CALOW RS06440
gene id: 632518:CALOW_RS06440
uniprot id: E4Q227
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

632518:CALOW RS02820
gene id: 632518:CALOW_RS02820
uniprot id: E4Q4Q4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS09940
gene id: 632518:CALOW_RS09940
uniprot id: E4Q5T4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

632518:CALOW RS04275
gene id: 632518:CALOW_RS04275
uniprot id: E4Q645
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

632518:CALOW RS00970
gene id: 632518:CALOW_RS00970
uniprot id: E4Q2P7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

632518:CALOW RS09750
gene id: 632518:CALOW_RS09750
uniprot id: E4Q5Q1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

632518:CALOW RS00425
gene id: 632518:CALOW_RS00425
uniprot id: E4Q267
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

632518:CALOW RS07010
gene id: 632518:CALOW_RS07010
uniprot id: E4Q2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

632518:CALOW RS09700
gene id: 632518:CALOW_RS09700
uniprot id: E4Q5G6
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS03505
gene id: 632518:CALOW_RS03505
uniprot id: E4Q5H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01470
gene id: 632518:CALOW_RS01470
uniprot id: E4Q355
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

632518:CALOW RS03480
gene id: 632518:CALOW_RS03480
uniprot id: E4Q5A2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

632518:CALOW RS07425
gene id: 632518:CALOW_RS07425
uniprot id: E4Q371
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

632518:CALOW RS08095
gene id: 632518:CALOW_RS08095
uniprot id: E4Q3S4
names: Similarity
messages: Belongs to the peptidase C40 family.

632518:CALOW RS07390
gene id: 632518:CALOW_RS07390
uniprot id: E4Q2Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

632518:CALOW RS07780
gene id: 632518:CALOW_RS07780
uniprot id: E4Q3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

632518:CALOW RS05960
gene id: 632518:CALOW_RS05960
uniprot id: E4Q1L5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

632518:CALOW RS10340
gene id: 632518:CALOW_RS10340
uniprot id: E4Q678
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS04560
gene id: 632518:CALOW_RS04560
uniprot id: E4Q6H7
names: Similarity
messages: Belongs to the HupF/HypC family.

632518:CALOW RS02125
gene id: 632518:CALOW_RS02125
uniprot id: E4Q3X4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

632518:CALOW RS07235
gene id: 632518:CALOW_RS07235
uniprot id: E4Q254
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS06295
gene id: 632518:CALOW_RS06295
uniprot id: E4Q1Z8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

632518:CALOW RS01830
gene id: 632518:CALOW_RS01830
uniprot id: E4Q3J4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

632518:CALOW RS03440
gene id: 632518:CALOW_RS03440
uniprot id: E4Q594
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

632518:CALOW RS09400
gene id: 632518:CALOW_RS09400
uniprot id: E4Q5B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

632518:CALOW RS01520
gene id: 632518:CALOW_RS01520
uniprot id: E4Q365
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

632518:CALOW RS02305
gene id: 632518:CALOW_RS02305
uniprot id: E4Q409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS09375
gene id: 632518:CALOW_RS09375
uniprot id: E4Q5A7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

632518:CALOW RS10985
gene id: 632518:CALOW_RS10985
uniprot id: E4Q700
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

632518:CALOW RS01975
gene id: 632518:CALOW_RS01975
uniprot id: E4Q3U6
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS03195
gene id: 632518:CALOW_RS03195
uniprot id: E4Q545
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

632518:CALOW RS06115
gene id: 632518:CALOW_RS06115
uniprot id: E4Q1P6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

632518:CALOW RS00650
gene id: 632518:CALOW_RS00650
uniprot id: E4Q2B0
names: Similarity
messages: Belongs to the RutC family.

632518:CALOW RS06180
gene id: 632518:CALOW_RS06180
uniprot id: E4Q1Q9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS06845
gene id: 632518:CALOW_RS06845
uniprot id: E4Q2H2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

632518:CALOW RS03925
gene id: 632518:CALOW_RS03925
uniprot id: E4Q5X8
names: Similarity
messages: Belongs to the asp23 family.

632518:CALOW RS04490
gene id: 632518:CALOW_RS04490
uniprot id: E4Q6G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

632518:CALOW RS09315
gene id: 632518:CALOW_RS09315
uniprot id: E4Q519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

632518:CALOW RS03855
gene id: 632518:CALOW_RS03855
uniprot id: E4Q5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

632518:CALOW RS03645
gene id: 632518:CALOW_RS03645
uniprot id: E4Q5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

632518:CALOW RS07610
gene id: 632518:CALOW_RS07610
uniprot id: E4Q3A8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632518:CALOW RS11435
gene id: 632518:CALOW_RS11435
uniprot id: E4Q1B6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

632518:CALOW RS10015
gene id: 632518:CALOW_RS10015
uniprot id: E4Q5U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

632518:CALOW RS09585
gene id: 632518:CALOW_RS09585
uniprot id: E4Q5E3
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS06920
gene id: 632518:CALOW_RS06920
uniprot id: E4Q2I9
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

632518:CALOW RS07460
gene id: 632518:CALOW_RS07460
uniprot id: E4Q378
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

632518:CALOW RS03310
gene id: 632518:CALOW_RS03310
uniprot id: E4Q568
names: Similarity
messages: Belongs to the IMPACT family.

632518:CALOW RS02380
gene id: 632518:CALOW_RS02380
uniprot id: E4Q497
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01235
gene id: 632518:CALOW_RS01235
uniprot id: E4Q315
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

632518:CALOW RS05255
gene id: 632518:CALOW_RS05255
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS02805
gene id: 632518:CALOW_RS02805
uniprot id: E4Q4Q1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

632518:CALOW RS07855
gene id: 632518:CALOW_RS07855
uniprot id: E4Q3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

632518:CALOW RS05700
gene id: 632518:CALOW_RS05700
uniprot id: E4Q1G6
names: Similarity
messages: Belongs to the YggT family.

632518:CALOW RS03405
gene id: 632518:CALOW_RS03405
uniprot id: E4Q587
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

632518:CALOW RS04720
gene id: 632518:CALOW_RS04720
uniprot id: E4Q6S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

632518:CALOW RS06625
gene id: 632518:CALOW_RS06625
uniprot id: E4Q256
names: Similarity
messages: Belongs to the asparagine synthetase family.

632518:CALOW RS00260
gene id: 632518:CALOW_RS00260
uniprot id: E4Q1W9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS04400
gene id: 632518:CALOW_RS04400
uniprot id: E4Q6E5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

632518:CALOW RS02330
gene id: 632518:CALOW_RS02330
uniprot id: E4Q414
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS07785
gene id: 632518:CALOW_RS07785
uniprot id: E4Q3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

632518:CALOW RS01885
gene id: 632518:CALOW_RS01885
uniprot id: E4Q3K4
names: Similarity
messages: Belongs to the leucine-binding protein family.

632518:CALOW RS02490
gene id: 632518:CALOW_RS02490
uniprot id: E4Q4C0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

632518:CALOW RS06015
gene id: 632518:CALOW_RS06015
uniprot id: E4Q1M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

632518:CALOW RS05235
gene id: 632518:CALOW_RS05235
uniprot id: E4Q148
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

632518:CALOW RS01460
gene id: 632518:CALOW_RS01460
uniprot id: E4Q353
names: Similarity
messages: Belongs to the hemerythrin family.

632518:CALOW RS04940
gene id: 632518:CALOW_RS04940
uniprot id: E4Q6W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

632518:CALOW RS09270
gene id: 632518:CALOW_RS09270
uniprot id: E4Q510
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

632518:CALOW RS11185
gene id: 632518:CALOW_RS11185
uniprot id: E4Q736
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

632518:CALOW RS08360
gene id: 632518:CALOW_RS08360
uniprot id: E4Q453
names: Similarity
messages: Belongs to the EamA transporter family.

632518:CALOW RS03145
gene id: 632518:CALOW_RS03145
uniprot id: E4Q535
names: Similarity
messages: Belongs to the UPF0749 family.

632518:CALOW RS10995
gene id: 632518:CALOW_RS10995
uniprot id: E4Q702
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS05550
gene id: 632518:CALOW_RS05550
uniprot id: E4Q1D5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

632518:CALOW RS10195
gene id: 632518:CALOW_RS10195
uniprot id: E4Q649
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

632518:CALOW RS03120
gene id: 632518:CALOW_RS03120
uniprot id: E4Q530
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

632518:CALOW RS08990
gene id: 632518:CALOW_RS08990
uniprot id: E4Q4V6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

632518:CALOW RS03160
gene id: 632518:CALOW_RS03160
uniprot id: E4Q538
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632518:CALOW RS07740
gene id: 632518:CALOW_RS07740
uniprot id: E4Q3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

632518:CALOW RS09950
gene id: 632518:CALOW_RS09950
uniprot id: E4Q5T6
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS10860
gene id: 632518:CALOW_RS10860
uniprot id: E4Q6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS09610
gene id: 632518:CALOW_RS09610
uniprot id: E4Q5E8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

632518:CALOW RS07395
gene id: 632518:CALOW_RS07395
uniprot id: E4Q2Z6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

632518:CALOW RS06075
gene id: 632518:CALOW_RS06075
uniprot id: E4Q1N8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

632518:CALOW RS00225
gene id: 632518:CALOW_RS00225
uniprot id: E4Q1W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

632518:CALOW RS01790
gene id: 632518:CALOW_RS01790
uniprot id: E4Q3I6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS04550
gene id: 632518:CALOW_RS04550
uniprot id: E4Q6H5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

632518:CALOW RS07360
gene id: 632518:CALOW_RS07360
uniprot id: E4Q2Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

632518:CALOW RS05985
gene id: 632518:CALOW_RS05985
uniprot id: E4Q1M0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

632518:CALOW RS01785
gene id: 632518:CALOW_RS01785
uniprot id: E4Q3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

632518:CALOW RS00885
gene id: 632518:CALOW_RS00885
uniprot id: E4Q2N0
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS08690
gene id: 632518:CALOW_RS08690
uniprot id: E4Q4I0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

632518:CALOW RS04295
gene id: 632518:CALOW_RS04295
uniprot id: E4Q6C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

632518:CALOW RS05845
gene id: 632518:CALOW_RS05845
uniprot id: E4Q1J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

632518:CALOW RS04745
gene id: 632518:CALOW_RS04745
uniprot id: E4Q6S8
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

632518:CALOW RS00075
gene id: 632518:CALOW_RS00075
uniprot id: E4Q1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

632518:CALOW RS07905
gene id: 632518:CALOW_RS07905
uniprot id: E4Q3N6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS02225
gene id: 632518:CALOW_RS02225
uniprot id: E4Q3Z4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS06450
gene id: 632518:CALOW_RS06450
uniprot id: E4Q229
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

632518:CALOW RS10305
gene id: 632518:CALOW_RS10305
uniprot id: E4Q672
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

632518:CALOW RS11345
gene id: 632518:CALOW_RS11345
uniprot id: E4Q198
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS09465
gene id: 632518:CALOW_RS09465
uniprot id: E4Q5C5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

632518:CALOW RS01435
gene id: 632518:CALOW_RS01435
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS02415
gene id: 632518:CALOW_RS02415
uniprot id: E4Q4A4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

632518:CALOW RS06185
gene id: 632518:CALOW_RS06185
uniprot id: E4Q1R0
names: Similarity
messages: Belongs to the HypE family.

632518:CALOW RS05155
gene id: 632518:CALOW_RS05155
uniprot id: E4Q133
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

632518:CALOW RS09155
gene id: 632518:CALOW_RS09155
uniprot id: E4Q4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

632518:CALOW RS03325
gene id: 632518:CALOW_RS03325
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS05070
gene id: 632518:CALOW_RS05070
uniprot id: E4Q116
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

632518:CALOW RS07830
gene id: 632518:CALOW_RS07830
uniprot id: E4Q3M1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS08710
gene id: 632518:CALOW_RS08710
uniprot id: E4Q4I4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632518:CALOW RS08700
gene id: 632518:CALOW_RS08700
uniprot id: E4Q4I2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

632518:CALOW RS02760
gene id: 632518:CALOW_RS02760
uniprot id: E4Q4P2
names: Similarity
messages: Belongs to the UPF0342 family.

632518:CALOW RS03625
gene id: 632518:CALOW_RS03625
uniprot id: E4Q5J8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

632518:CALOW RS09125
gene id: 632518:CALOW_RS09125
uniprot id: E4Q4Y1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

632518:CALOW RS02710
gene id: 632518:CALOW_RS02710
uniprot id: E4Q4N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632518:CALOW RS07125
gene id: 632518:CALOW_RS07125
uniprot id: E4Q2V1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

632518:CALOW RS00985
gene id: 632518:CALOW_RS00985
uniprot id: E4Q2Q0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

632518:CALOW RS02080
gene id: 632518:CALOW_RS02080
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS03000
gene id: 632518:CALOW_RS03000
uniprot id: E4Q4T6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

632518:CALOW RS04905
gene id: 632518:CALOW_RS04905
uniprot id: E4Q6W1
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS02130
gene id: 632518:CALOW_RS02130
uniprot id: E4Q3X5
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

632518:CALOW RS02550
gene id: 632518:CALOW_RS02550
uniprot id: E4Q4D2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS00795
gene id: 632518:CALOW_RS00795
uniprot id: E4Q2L3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS06010
gene id: 632518:CALOW_RS06010
uniprot id: E4Q1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

632518:CALOW RS08210
gene id: 632518:CALOW_RS08210
uniprot id: E4Q424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS04335
gene id: 632518:CALOW_RS04335
uniprot id: E4Q6D2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

632518:CALOW RS07485
gene id: 632518:CALOW_RS07485
uniprot id: E4Q383
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

632518:CALOW RS08415
gene id: 632518:CALOW_RS08415
uniprot id: E4Q464
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS08460
gene id: 632518:CALOW_RS08460
uniprot id: E4Q473
names: Similarity
messages: Belongs to the UPF0735 family.

632518:CALOW RS02300
gene id: 632518:CALOW_RS02300
uniprot id: E4Q408
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

632518:CALOW RS08845
gene id: 632518:CALOW_RS08845
uniprot id: E4Q4L2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

632518:CALOW RS02395
gene id: 632518:CALOW_RS02395
uniprot id: E4Q254
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS04835
gene id: 632518:CALOW_RS04835
uniprot id: E4Q6U7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

632518:CALOW RS07575
gene id: 632518:CALOW_RS07575
uniprot id: E4Q3A1
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS05930
gene id: 632518:CALOW_RS05930
uniprot id: E4Q1K9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

632518:CALOW RS07475
gene id: 632518:CALOW_RS07475
uniprot id: E4Q381
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

632518:CALOW RS06280
gene id: 632518:CALOW_RS06280
uniprot id: E4Q1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

632518:CALOW RS06100
gene id: 632518:CALOW_RS06100
uniprot id: E4Q1P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

632518:CALOW RS02180
gene id: 632518:CALOW_RS02180
uniprot id: E4Q3Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS05880
gene id: 632518:CALOW_RS05880
uniprot id: E4Q1J9
names: Similarity
messages: Belongs to the leucine-binding protein family.

632518:CALOW RS07405
gene id: 632518:CALOW_RS07405
uniprot id: E4Q2Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

632518:CALOW RS03205
gene id: 632518:CALOW_RS03205
uniprot id: E4Q547
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS02890
gene id: 632518:CALOW_RS02890
uniprot id: E4Q4R6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

632518:CALOW RS06150
gene id: 632518:CALOW_RS06150
uniprot id: E4Q1Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

632518:CALOW RS07445
gene id: 632518:CALOW_RS07445
uniprot id: E4Q375
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

632518:CALOW RS07630
gene id: 632518:CALOW_RS07630
uniprot id: E4Q3B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

632518:CALOW RS06375
gene id: 632518:CALOW_RS06375
uniprot id: E4Q214
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

632518:CALOW RS04645
gene id: 632518:CALOW_RS04645
uniprot id: E4Q6J2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

632518:CALOW RS03180
gene id: 632518:CALOW_RS03180
uniprot id: E4Q542
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

632518:CALOW RS08110
gene id: 632518:CALOW_RS08110
uniprot id: E4Q3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

632518:CALOW RS08065
gene id: 632518:CALOW_RS08065
uniprot id: E4Q3R8
names: Similarity
messages: Belongs to the GSP E family.

632518:CALOW RS02240
gene id: 632518:CALOW_RS02240
uniprot id: E4Q3Z7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS02000
gene id: 632518:CALOW_RS02000
uniprot id: E4Q3V1
names: Similarity
messages: Belongs to the UPF0145 family.

632518:CALOW RS04380
gene id: 632518:CALOW_RS04380
uniprot id: E4Q6E1
names: Similarity
messages: Belongs to the ribF family.

632518:CALOW RS06435
gene id: 632518:CALOW_RS06435
uniprot id: E4Q226
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632518:CALOW RS02005
gene id: 632518:CALOW_RS02005
uniprot id: E4Q3V2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632518:CALOW RS07850
gene id: 632518:CALOW_RS07850
uniprot id: E4Q3M5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS03785
gene id: 632518:CALOW_RS03785
uniprot id: E4Q5M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

632518:CALOW RS06940
gene id: 632518:CALOW_RS06940
uniprot id: E4Q2J3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

632518:CALOW RS07180
gene id: 632518:CALOW_RS07180
uniprot id: E4Q2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

632518:CALOW RS01100
gene id: 632518:CALOW_RS01100
uniprot id: E4Q2S2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS04715
gene id: 632518:CALOW_RS04715
uniprot id: E4Q6S2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

632518:CALOW RS01490
gene id: 632518:CALOW_RS01490
uniprot id: E4Q359
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

632518:CALOW RS01380
gene id: 632518:CALOW_RS01380
uniprot id: E4Q338
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

632518:CALOW RS07560
gene id: 632518:CALOW_RS07560
uniprot id: E4Q398
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

632518:CALOW RS03840
gene id: 632518:CALOW_RS03840
uniprot id: E4Q5P0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632518:CALOW RS07165
gene id: 632518:CALOW_RS07165
uniprot id: E4Q2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01180
gene id: 632518:CALOW_RS01180
uniprot id: E4Q304
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632518:CALOW RS11005
gene id: 632518:CALOW_RS11005
uniprot id: E4Q704
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS04735
gene id: 632518:CALOW_RS04735
uniprot id: E4Q6S6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632518:CALOW RS04800
gene id: 632518:CALOW_RS04800
uniprot id: E4Q6T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

632518:CALOW RS00520
gene id: 632518:CALOW_RS00520
uniprot id: E4Q254
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS06390
gene id: 632518:CALOW_RS06390
uniprot id: E4Q217
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632518:CALOW RS07625
gene id: 632518:CALOW_RS07625
uniprot id: E4Q3B1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS04895
gene id: 632518:CALOW_RS04895
uniprot id: E4Q6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

632518:CALOW RS07720
gene id: 632518:CALOW_RS07720
uniprot id: E4Q3D0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

632518:CALOW RS08850
gene id: 632518:CALOW_RS08850
uniprot id: E4Q4L3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

632518:CALOW RS07685
gene id: 632518:CALOW_RS07685
uniprot id: E4Q3C3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

632518:CALOW RS09105
gene id: 632518:CALOW_RS09105
uniprot id: E4Q4X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS01775
gene id: 632518:CALOW_RS01775
uniprot id: E4Q3I3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

632518:CALOW RS08530
gene id: 632518:CALOW_RS08530
uniprot id: E4Q485
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

632518:CALOW RS10670
gene id: 632518:CALOW_RS10670
uniprot id: E4Q6M2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

632518:CALOW RS01350
gene id: 632518:CALOW_RS01350
uniprot id: E4Q332
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

632518:CALOW RS09395
gene id: 632518:CALOW_RS09395
uniprot id: E4Q5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

632518:CALOW RS11375
gene id: 632518:CALOW_RS11375
uniprot id: E4Q1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

632518:CALOW RS04920
gene id: 632518:CALOW_RS04920
uniprot id: E4Q6W2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

632518:CALOW RS08535
gene id: 632518:CALOW_RS08535
uniprot id: E4Q486
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

632518:CALOW RS00005
gene id: 632518:CALOW_RS00005
uniprot id: E4Q1S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

632518:CALOW RS06420
gene id: 632518:CALOW_RS06420
uniprot id: E4Q223
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632518:CALOW RS01995
gene id: 632518:CALOW_RS01995
uniprot id: E4Q3V0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS06640
gene id: 632518:CALOW_RS06640
uniprot id: E4Q2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

632518:CALOW RS09525
gene id: 632518:CALOW_RS09525
uniprot id: E4Q5D3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

632518:CALOW RS02205
gene id: 632518:CALOW_RS02205
uniprot id: E4Q3Z0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

632518:CALOW RS08895
gene id: 632518:CALOW_RS08895
uniprot id: E4Q4M0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632518:CALOW RS03545
gene id: 632518:CALOW_RS03545
uniprot id: E4Q5I4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632518:CALOW RS06690
gene id: 632518:CALOW_RS06690
uniprot id: E4Q2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

632518:CALOW RS06020
gene id: 632518:CALOW_RS06020
uniprot id: E4Q1M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

632518:CALOW RS09990
gene id: 632518:CALOW_RS09990
uniprot id: E4Q5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

632518:CALOW RS08045
gene id: 632518:CALOW_RS08045
uniprot id: E4Q3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

632518:CALOW RS07930
gene id: 632518:CALOW_RS07930
uniprot id: E4Q3P1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

632518:CALOW RS09755
gene id: 632518:CALOW_RS09755
uniprot id: E4Q5Q2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

632518:CALOW RS05420
gene id: 632518:CALOW_RS05420
uniprot id: E4Q184
names: Similarity
messages: Belongs to the TlyA family.

632518:CALOW RS05495
gene id: 632518:CALOW_RS05495
uniprot id: E4Q1C4
names: Similarity
messages: Belongs to the class-D beta-lactamase family.
messages: Belongs to the transpeptidase family.

632518:CALOW RS10695
gene id: 632518:CALOW_RS10695
uniprot id: E4Q6M7
names: Similarity
messages: Belongs to the FGGY kinase family.

632518:CALOW RS05465
gene id: 632518:CALOW_RS05465
uniprot id: E4Q193
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

632518:CALOW RS06340
gene id: 632518:CALOW_RS06340
uniprot id: E4Q207
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

632518:CALOW RS04740
gene id: 632518:CALOW_RS04740
uniprot id: E4Q6S7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

632518:CALOW RS07355
gene id: 632518:CALOW_RS07355
uniprot id: E4Q2Y8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

632518:CALOW RS02070
gene id: 632518:CALOW_RS02070
uniprot id: E4Q3W5
names: Similarity
messages: Belongs to the UPF0758 family.

632518:CALOW RS02290
gene id: 632518:CALOW_RS02290
uniprot id: E4Q406
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS06130
gene id: 632518:CALOW_RS06130
uniprot id: E4Q1P9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS06260
gene id: 632518:CALOW_RS06260
uniprot id: E4Q1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

632518:CALOW RS06265
gene id: 632518:CALOW_RS06265
uniprot id: E4Q1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

632518:CALOW RS03330
gene id: 632518:CALOW_RS03330
uniprot id: E4Q572
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

632518:CALOW RS07820
gene id: 632518:CALOW_RS07820
uniprot id: E4Q3L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

632518:CALOW RS07455
gene id: 632518:CALOW_RS07455
uniprot id: E4Q377
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

632518:CALOW RS00345
gene id: 632518:CALOW_RS00345
uniprot id: E4Q1Y1
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

632518:CALOW RS04125
gene id: 632518:CALOW_RS04125
uniprot id: E4Q616
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

632518:CALOW RS11095
gene id: 632518:CALOW_RS11095
uniprot id: E4Q719
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS06980
gene id: 632518:CALOW_RS06980
uniprot id: E4Q2K1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

632518:CALOW RS01575
gene id: 632518:CALOW_RS01575
uniprot id: E4Q3F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

632518:CALOW RS01820
gene id: 632518:CALOW_RS01820
uniprot id: E4Q3J2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

632518:CALOW RS07430
gene id: 632518:CALOW_RS07430
uniprot id: E4Q372
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

632518:CALOW RS06890
gene id: 632518:CALOW_RS06890
uniprot id: E4Q2I2
names: Similarity
messages: Belongs to the EamA transporter family.

632518:CALOW RS10565
gene id: 632518:CALOW_RS10565
uniprot id: E4Q6K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632518:CALOW RS10250
gene id: 632518:CALOW_RS10250
uniprot id: E4Q660
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632518:CALOW RS04235
gene id: 632518:CALOW_RS04235
uniprot id: E4Q638
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

632518:CALOW RS02155
gene id: 632518:CALOW_RS02155
uniprot id: E4Q3Y0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

632518:CALOW RS08445
gene id: 632518:CALOW_RS08445
uniprot id: E4Q470
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

632518:CALOW RS06300
gene id: 632518:CALOW_RS06300
uniprot id: E4Q1Z9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

632518:CALOW RS02850
gene id: 632518:CALOW_RS02850
uniprot id: E4Q4Q8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632518:CALOW RS09110
gene id: 632518:CALOW_RS09110
uniprot id: E4Q4X8
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

632518:CALOW RS08545
gene id: 632518:CALOW_RS08545
uniprot id: E4Q488
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

632518:CALOW RS02870
gene id: 632518:CALOW_RS02870
uniprot id: E4Q4R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

632518:CALOW RS02980
gene id: 632518:CALOW_RS02980
uniprot id: E4Q4T2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

632518:CALOW RS08150
gene id: 632518:CALOW_RS08150
uniprot id: E4Q3T5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

632518:CALOW RS06400
gene id: 632518:CALOW_RS06400
uniprot id: E4Q219
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

632518:CALOW RS02715
gene id: 632518:CALOW_RS02715
uniprot id: E4Q4N5
names: Similarity
messages: Belongs to the UPF0047 family.

632518:CALOW RS04865
gene id: 632518:CALOW_RS04865
uniprot id: E4Q6V3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

632518:CALOW RS00035
gene id: 632518:CALOW_RS00035
uniprot id: E4Q1S8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

632518:CALOW RS05805
gene id: 632518:CALOW_RS05805
uniprot id: E4Q1I4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

632518:CALOW RS07915
gene id: 632518:CALOW_RS07915
uniprot id: E4Q3N8
names: Similarity
messages: Belongs to the CtsR family.

632518:CALOW RS07225
gene id: 632518:CALOW_RS07225
uniprot id: E4Q2W9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632518:CALOW RS05475
gene id: 632518:CALOW_RS05475
uniprot id: E4Q1C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

632518:CALOW RS03115
gene id: 632518:CALOW_RS03115
uniprot id: E4Q529
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01825
gene id: 632518:CALOW_RS01825
uniprot id: E4Q3J3
names: Similarity
messages: Belongs to the class-I fumarase family.

632518:CALOW RS02390
gene id: 632518:CALOW_RS02390
uniprot id: E4Q499
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

632518:CALOW RS10660
gene id: 632518:CALOW_RS10660
uniprot id: E4Q6M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

632518:CALOW RS11130
gene id: 632518:CALOW_RS11130
uniprot id: E4Q726
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS00615
gene id: 632518:CALOW_RS00615
uniprot id: E4Q2A3
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

632518:CALOW RS08425
gene id: 632518:CALOW_RS08425
uniprot id: E4Q466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS01410
gene id: 632518:CALOW_RS01410
uniprot id: E4Q344
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

632518:CALOW RS05310
gene id: 632518:CALOW_RS05310
uniprot id: E4Q163
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

632518:CALOW RS09385
gene id: 632518:CALOW_RS09385
uniprot id: E4Q5A9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

632518:CALOW RS04255
gene id: 632518:CALOW_RS04255
uniprot id: E4Q641
names: Similarity
messages: Belongs to the histone deacetylase family.

632518:CALOW RS02590
gene id: 632518:CALOW_RS02590
uniprot id: E4Q4E0
names: Similarity
messages: Belongs to the glutamine synthetase family.

632518:CALOW RS05085
gene id: 632518:CALOW_RS05085
uniprot id: E4Q119
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

632518:CALOW RS02475
gene id: 632518:CALOW_RS02475
uniprot id: E4Q4B6
names: Similarity
messages: Belongs to the PGI/PMI family.

632518:CALOW RS03425
gene id: 632518:CALOW_RS03425
uniprot id: E4Q591
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS03320
gene id: 632518:CALOW_RS03320
uniprot id: E4Q570
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS08170
gene id: 632518:CALOW_RS08170
uniprot id: E4Q416
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

632518:CALOW RS09555
gene id: 632518:CALOW_RS09555
uniprot id: E4Q5D8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

632518:CALOW RS05060
gene id: 632518:CALOW_RS05060
uniprot id: E4Q6Z0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS09290
gene id: 632518:CALOW_RS09290
uniprot id: E4Q514
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

632518:CALOW RS06270
gene id: 632518:CALOW_RS06270
uniprot id: E4Q1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

632518:CALOW RS07175
gene id: 632518:CALOW_RS07175
uniprot id: E4Q2V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

632518:CALOW RS03820
gene id: 632518:CALOW_RS03820
uniprot id: E4Q5N6
names: Similarity
messages: Belongs to the UPF0102 family.

632518:CALOW RS03525
gene id: 632518:CALOW_RS03525
uniprot id: E4Q5I0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS05815
gene id: 632518:CALOW_RS05815
uniprot id: E4Q1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

632518:CALOW RS08440
gene id: 632518:CALOW_RS08440
uniprot id: E4Q469
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

632518:CALOW RS10735
gene id: 632518:CALOW_RS10735
uniprot id: E4Q6N5
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

632518:CALOW RS03135
gene id: 632518:CALOW_RS03135
uniprot id: E4Q533
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS07665
gene id: 632518:CALOW_RS07665
uniprot id: E4Q3B9
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS06105
gene id: 632518:CALOW_RS06105
uniprot id: E4Q1P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

632518:CALOW RS01595
gene id: 632518:CALOW_RS01595
uniprot id: E4Q3F4
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS03800
gene id: 632518:CALOW_RS03800
uniprot id: E4Q5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

632518:CALOW RS03250
gene id: 632518:CALOW_RS03250
uniprot id: E4Q556
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS08070
gene id: 632518:CALOW_RS08070
uniprot id: E4Q3R9
names: Similarity
messages: Belongs to the GSP E family.

632518:CALOW RS10855
gene id: 632518:CALOW_RS10855
uniprot id: E4Q6Q3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

632518:CALOW RS05415
gene id: 632518:CALOW_RS05415
uniprot id: E4Q183
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

632518:CALOW RS08800
gene id: 632518:CALOW_RS08800
uniprot id: E4Q4K2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS02695
gene id: 632518:CALOW_RS02695
uniprot id: E4Q4G1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

632518:CALOW RS00945
gene id: 632518:CALOW_RS00945
uniprot id: E4Q2P2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS04855
gene id: 632518:CALOW_RS04855
uniprot id: E4Q6V1
names: Similarity
messages: Belongs to the fabD family.

632518:CALOW RS11400
gene id: 632518:CALOW_RS11400
uniprot id: E4Q1A9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS02335
gene id: 632518:CALOW_RS02335
uniprot id: E4Q415
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS07680
gene id: 632518:CALOW_RS07680
uniprot id: E4Q3C2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

632518:CALOW RS07825
gene id: 632518:CALOW_RS07825
uniprot id: E4Q3M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

632518:CALOW RS04465
gene id: 632518:CALOW_RS04465
uniprot id: E4Q6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

632518:CALOW RS05595
gene id: 632518:CALOW_RS05595
uniprot id: E4Q1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

632518:CALOW RS03390
gene id: 632518:CALOW_RS03390
uniprot id: E4Q584
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

632518:CALOW RS05485
gene id: 632518:CALOW_RS05485
uniprot id: E4Q1C2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

632518:CALOW RS08220
gene id: 632518:CALOW_RS08220
uniprot id: E4Q426
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

632518:CALOW RS08970
gene id: 632518:CALOW_RS08970
uniprot id: E4Q4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS07800
gene id: 632518:CALOW_RS07800
uniprot id: E4Q3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

632518:CALOW RS07535
gene id: 632518:CALOW_RS07535
uniprot id: E4Q393
names: Similarity
messages: Belongs to the peptidase M18 family.

632518:CALOW RS09145
gene id: 632518:CALOW_RS09145
uniprot id: E4Q4Y5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

632518:CALOW RS11120
gene id: 632518:CALOW_RS11120
uniprot id: E4Q724
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

632518:CALOW RS09295
gene id: 632518:CALOW_RS09295
uniprot id: E4Q515
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

632518:CALOW RS01425
gene id: 632518:CALOW_RS01425
uniprot id: E4Q347
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

632518:CALOW RS07655
gene id: 632518:CALOW_RS07655
uniprot id: E4Q3B7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

632518:CALOW RS01800
gene id: 632518:CALOW_RS01800
uniprot id: E4Q3I9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

632518:CALOW RS07105
gene id: 632518:CALOW_RS07105
uniprot id: E4Q2U7
names: Similarity
messages: Belongs to the FlgM family.

632518:CALOW RS05005
gene id: 632518:CALOW_RS05005
uniprot id: E4Q6X9
names: Similarity
messages: Belongs to the UPF0297 family.

632518:CALOW RS02995
gene id: 632518:CALOW_RS02995
uniprot id: E4Q4T5
names: Subcellular Location Annotation
messages: Cytoplasm

632518:CALOW RS08080
gene id: 632518:CALOW_RS08080
uniprot id: E4Q3S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

632518:CALOW RS06955
gene id: 632518:CALOW_RS06955
uniprot id: E4Q2J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

632518:CALOW RS09970
gene id: 632518:CALOW_RS09970
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS10300
gene id: 632518:CALOW_RS10300
uniprot id: E4Q671
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

632518:CALOW RS07725
gene id: 632518:CALOW_RS07725
uniprot id: E4Q3D1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

632518:CALOW RS07960
gene id: 632518:CALOW_RS07960
uniprot id: E4Q3P7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

632518:CALOW RS05645
gene id: 632518:CALOW_RS05645
uniprot id: E4Q1F5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

632518:CALOW RS05150
gene id: 632518:CALOW_RS05150
uniprot id: E4Q132
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

632518:CALOW RS03385
gene id: 632518:CALOW_RS03385
uniprot id: E4Q583
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

632518:CALOW RS07835
gene id: 632518:CALOW_RS07835
uniprot id: E4Q3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

632518:CALOW RS01130
gene id: 632518:CALOW_RS01130
uniprot id: E4Q2S8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632518:CALOW RS04830
gene id: 632518:CALOW_RS04830
uniprot id: E4Q6U6
names: Similarity
messages: Belongs to the UPF0473 family.

632518:CALOW RS02935
gene id: 632518:CALOW_RS02935
uniprot id: E4Q4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

632518:CALOW RS06140
gene id: 632518:CALOW_RS06140
uniprot id: E4Q1Q1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

632518:CALOW RS08060
gene id: 632518:CALOW_RS08060
uniprot id: E4Q3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS04640
gene id: 632518:CALOW_RS04640
uniprot id: E4Q6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS06810
gene id: 632518:CALOW_RS06810
uniprot id: E4Q2G6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

632518:CALOW RS08715
gene id: 632518:CALOW_RS08715
uniprot id: E4Q4I5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

632518:CALOW RS09770
gene id: 632518:CALOW_RS09770
uniprot id: E4Q5Q5
names: Similarity
messages: Belongs to the universal stress protein A family.

632518:CALOW RS10345
gene id: 632518:CALOW_RS10345
uniprot id: E4Q679
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

632518:CALOW RS07400
gene id: 632518:CALOW_RS07400
uniprot id: E4Q2Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

632518:CALOW RS01135
gene id: 632518:CALOW_RS01135
uniprot id: E4Q2S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Cell membrane
messages: Probably a homodimer.

632518:CALOW RS03050
gene id: 632518:CALOW_RS03050
uniprot id: E4Q4U1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

632518:CALOW RS09005
gene id: 632518:CALOW_RS09005
uniprot id: E4Q4V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS04695
gene id: 632518:CALOW_RS04695
uniprot id: E4Q6R8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

632518:CALOW RS11395
gene id: 632518:CALOW_RS11395
uniprot id: E4Q1A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

632518:CALOW RS07500
gene id: 632518:CALOW_RS07500
uniprot id: E4Q386
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

632518:CALOW RS10055
gene id: 632518:CALOW_RS10055
uniprot id: E4Q5V4
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS04495
gene id: 632518:CALOW_RS04495
uniprot id: E4Q6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

632518:CALOW RS09035
gene id: 632518:CALOW_RS09035
uniprot id: E4Q4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

632518:CALOW RS02525
gene id: 632518:CALOW_RS02525
uniprot id: E4Q4C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS11440
gene id: 632518:CALOW_RS11440
uniprot id: E4Q1B7
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

632518:CALOW RS00365
gene id: 632518:CALOW_RS00365
uniprot id: E4Q1Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

632518:CALOW RS07465
gene id: 632518:CALOW_RS07465
uniprot id: E4Q379
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

632518:CALOW RS10080
gene id: 632518:CALOW_RS10080
uniprot id: E4Q5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

632518:CALOW RS04035
gene id: 632518:CALOW_RS04035
uniprot id: E4Q5Z8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632518:CALOW RS00360
gene id: 632518:CALOW_RS00360
uniprot id: E4Q1Y4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

632518:CALOW RS05775
gene id: 632518:CALOW_RS05775
uniprot id: E4Q1H8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

632518:CALOW RS04525
gene id: 632518:CALOW_RS04525
uniprot id: E4Q6H0
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

632518:CALOW RS07640
gene id: 632518:CALOW_RS07640
uniprot id: E4Q3B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

632518:CALOW RS05340
gene id: 632518:CALOW_RS05340
uniprot id: E4Q169
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

632518:CALOW RS09345
gene id: 632518:CALOW_RS09345
uniprot id: E4Q525
names: Similarity
messages: Belongs to the FlgD family.

632518:CALOW RS02500
gene id: 632518:CALOW_RS02500
uniprot id: E4Q4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

632518:CALOW RS03565
gene id: 632518:CALOW_RS03565
uniprot id: E4Q5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632518:CALOW RS08235
gene id: 632518:CALOW_RS08235
uniprot id: E4Q429
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS05135
gene id: 632518:CALOW_RS05135
uniprot id: E4Q129
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

632518:CALOW RS05810
gene id: 632518:CALOW_RS05810
uniprot id: E4Q1I5
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

632518:CALOW RS03155
gene id: 632518:CALOW_RS03155
uniprot id: E4Q537
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

632518:CALOW RS03760
gene id: 632518:CALOW_RS03760
uniprot id: E4Q5M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632518:CALOW RS02460
gene id: 632518:CALOW_RS02460
uniprot id: E4Q4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS02505
gene id: 632518:CALOW_RS02505
uniprot id: E4Q4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

632518:CALOW RS03045
gene id: 632518:CALOW_RS03045
uniprot id: E4Q4U0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

632518:CALOW RS06025
gene id: 632518:CALOW_RS06025
uniprot id: E4Q1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

632518:CALOW RS03640
gene id: 632518:CALOW_RS03640
uniprot id: E4Q5K1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS07330
gene id: 632518:CALOW_RS07330
uniprot id: E4Q2Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

632518:CALOW RS07080
gene id: 632518:CALOW_RS07080
uniprot id: E4Q2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

632518:CALOW RS04285
gene id: 632518:CALOW_RS04285
uniprot id: E4Q6C2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS09410
gene id: 632518:CALOW_RS09410
uniprot id: E4Q5B4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

632518:CALOW RS00730
gene id: 632518:CALOW_RS00730
uniprot id: E4Q2C6
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

632518:CALOW RS03580
gene id: 632518:CALOW_RS03580
uniprot id: E4Q5I9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS08395
gene id: 632518:CALOW_RS08395
uniprot id: E4Q460
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

632518:CALOW RS02055
gene id: 632518:CALOW_RS02055
uniprot id: E4Q3W2
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

632518:CALOW RS07190
gene id: 632518:CALOW_RS07190
uniprot id: E4Q2W2
names: Similarity
messages: Belongs to the TrpC family.

632518:CALOW RS04470
gene id: 632518:CALOW_RS04470
uniprot id: E4Q6F9
names: Similarity
messages: Belongs to the MotB family.

632518:CALOW RS04460
gene id: 632518:CALOW_RS04460
uniprot id: E4Q6F7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

632518:CALOW RS10520
gene id: 632518:CALOW_RS10520
uniprot id: E4Q6B4
names: Similarity
messages: Belongs to the glutamate synthase family.

632518:CALOW RS04570
gene id: 632518:CALOW_RS04570
uniprot id: E4Q6H9
names: Similarity
messages: Belongs to the HypE family.

632518:CALOW RS05265
gene id: 632518:CALOW_RS05265
uniprot id: E4Q154
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

632518:CALOW RS00285
gene id: 632518:CALOW_RS00285
uniprot id: E4Q1X3
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS09050
gene id: 632518:CALOW_RS09050
uniprot id: E4Q4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

632518:CALOW RS04990
gene id: 632518:CALOW_RS04990
uniprot id: E4Q6X6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

632518:CALOW RS01385
gene id: 632518:CALOW_RS01385
uniprot id: E4Q339
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

632518:CALOW RS03285
gene id: 632518:CALOW_RS03285
uniprot id: E4Q563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

632518:CALOW RS02800
gene id: 632518:CALOW_RS02800
uniprot id: E4Q4Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

632518:CALOW RS08875
gene id: 632518:CALOW_RS08875
uniprot id: E4Q4L6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

632518:CALOW RS07215
gene id: 632518:CALOW_RS07215
uniprot id: E4Q2W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

632518:CALOW RS06055
gene id: 632518:CALOW_RS06055
uniprot id: E4Q1N4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

632518:CALOW RS08350
gene id: 632518:CALOW_RS08350
uniprot id: E4Q451
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01950
gene id: 632518:CALOW_RS01950
uniprot id: E4Q3U2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632518:CALOW RS06290
gene id: 632518:CALOW_RS06290
uniprot id: E4Q1Z7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

632518:CALOW RS03790
gene id: 632518:CALOW_RS03790
uniprot id: E4Q5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

632518:CALOW RS02140
gene id: 632518:CALOW_RS02140
uniprot id: E4Q3X7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

632518:CALOW RS08865
gene id: 632518:CALOW_RS08865
uniprot id: E4Q4L4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

632518:CALOW RS09475
gene id: 632518:CALOW_RS09475
uniprot id: E4Q5C6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632518:CALOW RS10740
gene id: 632518:CALOW_RS10740
uniprot id: E4Q6N6
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

632518:CALOW RS05835
gene id: 632518:CALOW_RS05835
uniprot id: E4Q1J0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS05065
gene id: 632518:CALOW_RS05065
uniprot id: E4Q6Z1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

632518:CALOW RS07410
gene id: 632518:CALOW_RS07410
uniprot id: E4Q2Z9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

632518:CALOW RS01480
gene id: 632518:CALOW_RS01480
uniprot id: E4Q357
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

632518:CALOW RS07845
gene id: 632518:CALOW_RS07845
uniprot id: E4Q3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

632518:CALOW RS02045
gene id: 632518:CALOW_RS02045
uniprot id: E4Q3W0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

632518:CALOW RS03805
gene id: 632518:CALOW_RS03805
uniprot id: E4Q5N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

632518:CALOW RS04390
gene id: 632518:CALOW_RS04390
uniprot id: E4Q6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

632518:CALOW RS07440
gene id: 632518:CALOW_RS07440
uniprot id: E4Q374
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

632518:CALOW RS08770
gene id: 632518:CALOW_RS08770
uniprot id: E4Q4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

632518:CALOW RS02555
gene id: 632518:CALOW_RS02555
uniprot id: E4Q4D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

632518:CALOW RS05215
gene id: 632518:CALOW_RS05215
uniprot id: E4Q144
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS02880
gene id: 632518:CALOW_RS02880
uniprot id: E4Q4R4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

632518:CALOW RS02765
gene id: 632518:CALOW_RS02765
uniprot id: E4Q4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

632518:CALOW RS04300
gene id: 632518:CALOW_RS04300
uniprot id: E4Q6C5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

632518:CALOW RS06500
gene id: 632518:CALOW_RS06500
uniprot id: E4Q234
names: Similarity
messages: Belongs to the peptidase S16 family.

632518:CALOW RS04480
gene id: 632518:CALOW_RS04480
uniprot id: E4Q6G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

632518:CALOW RS09805
gene id: 632518:CALOW_RS09805
uniprot id: E4Q5R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS05840
gene id: 632518:CALOW_RS05840
uniprot id: E4Q1J1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

632518:CALOW RS03030
gene id: 632518:CALOW_RS03030
uniprot id: E4Q4T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

632518:CALOW RS06670
gene id: 632518:CALOW_RS06670
uniprot id: E4Q2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

632518:CALOW RS09180
gene id: 632518:CALOW_RS09180
uniprot id: E4Q4Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS06735
gene id: 632518:CALOW_RS06735
uniprot id: E4Q2F3
names: Similarity
messages: Belongs to the SleB family.

632518:CALOW RS04985
gene id: 632518:CALOW_RS04985
uniprot id: E4Q6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

632518:CALOW RS00690
gene id: 632518:CALOW_RS00690
uniprot id: E4Q2B8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632518:CALOW RS09045
gene id: 632518:CALOW_RS09045
uniprot id: E4Q4W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

632518:CALOW RS10580
gene id: 632518:CALOW_RS10580
uniprot id: E4Q6K4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS08975
gene id: 632518:CALOW_RS08975
uniprot id: E4Q4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS10640
gene id: 632518:CALOW_RS10640
uniprot id: E4Q6L6
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

632518:CALOW RS00905
gene id: 632518:CALOW_RS00905
uniprot id: E4Q2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

632518:CALOW RS10415
gene id: 632518:CALOW_RS10415
uniprot id: E4Q693
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

632518:CALOW RS00010
gene id: 632518:CALOW_RS00010
uniprot id: E4Q1S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

632518:CALOW RS05115
gene id: 632518:CALOW_RS05115
uniprot id: E4Q125
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS02035
gene id: 632518:CALOW_RS02035
uniprot id: E4Q3V8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

632518:CALOW RS07840
gene id: 632518:CALOW_RS07840
uniprot id: E4Q3M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

632518:CALOW RS07865
gene id: 632518:CALOW_RS07865
uniprot id: E4Q3M8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

632518:CALOW RS00315
gene id: 632518:CALOW_RS00315
uniprot id: E4Q1X5
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS07055
gene id: 632518:CALOW_RS07055
uniprot id: E4Q2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

632518:CALOW RS08655
gene id: 632518:CALOW_RS08655
uniprot id: E4Q4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS00810
gene id: 632518:CALOW_RS00810
uniprot id: E4Q2L5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632518:CALOW RS10960
gene id: 632518:CALOW_RS10960
uniprot id: E4Q6Z5
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

632518:CALOW RS06335
gene id: 632518:CALOW_RS06335
uniprot id: E4Q206
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS04925
gene id: 632518:CALOW_RS04925
uniprot id: E4Q6W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

632518:CALOW RS02470
gene id: 632518:CALOW_RS02470
uniprot id: E4Q4B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632518:CALOW RS04385
gene id: 632518:CALOW_RS04385
uniprot id: E4Q6E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

632518:CALOW RS06560
gene id: 632518:CALOW_RS06560
uniprot id: E4Q246
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

632518:CALOW RS05390
gene id: 632518:CALOW_RS05390
uniprot id: E4Q179
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

632518:CALOW RS08160
gene id: 632518:CALOW_RS08160
uniprot id: E4Q3T7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

632518:CALOW RS00565
gene id: 632518:CALOW_RS00565
uniprot id: E4Q293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS04315
gene id: 632518:CALOW_RS04315
uniprot id: E4Q6C8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

632518:CALOW RS09030
gene id: 632518:CALOW_RS09030
uniprot id: E4Q4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

632518:CALOW RS09285
gene id: 632518:CALOW_RS09285
uniprot id: E4Q513
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

632518:CALOW RS03955
gene id: 632518:CALOW_RS03955
uniprot id: E4Q5Y4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

632518:CALOW RS01145
gene id: 632518:CALOW_RS01145
uniprot id: E4Q2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

632518:CALOW RS04685
gene id: 632518:CALOW_RS04685
uniprot id: E4Q6R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

632518:CALOW RS07670
gene id: 632518:CALOW_RS07670
uniprot id: E4Q3C0
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS08995
gene id: 632518:CALOW_RS08995
uniprot id: E4Q4V7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

632518:CALOW RS11055
gene id: 632518:CALOW_RS11055
uniprot id: E4Q713
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS10025
gene id: 632518:CALOW_RS10025
uniprot id: E4Q5U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

632518:CALOW RS03280
gene id: 632518:CALOW_RS03280
uniprot id: E4Q562
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

632518:CALOW RS08650
gene id: 632518:CALOW_RS08650
uniprot id: E4Q4H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01220
gene id: 632518:CALOW_RS01220
uniprot id: E4Q312
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

632518:CALOW RS10460
gene id: 632518:CALOW_RS10460
uniprot id: E4Q6A2
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS07320
gene id: 632518:CALOW_RS07320
uniprot id: E4Q2Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS00430
gene id: 632518:CALOW_RS00430
uniprot id: E4Q268
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

632518:CALOW RS05605
gene id: 632518:CALOW_RS05605
uniprot id: E4Q1E7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

632518:CALOW RS09205
gene id: 632518:CALOW_RS09205
uniprot id: E4Q4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

632518:CALOW RS10605
gene id: 632518:CALOW_RS10605
uniprot id: E4Q6K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

632518:CALOW RS05870
gene id: 632518:CALOW_RS05870
uniprot id: E4Q1J7
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS07435
gene id: 632518:CALOW_RS07435
uniprot id: E4Q373
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

632518:CALOW RS06345
gene id: 632518:CALOW_RS06345
uniprot id: E4Q208
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

632518:CALOW RS03375
gene id: 632518:CALOW_RS03375
uniprot id: E4Q581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS08475
gene id: 632518:CALOW_RS08475
uniprot id: E4Q476
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

632518:CALOW RS02875
gene id: 632518:CALOW_RS02875
uniprot id: E4Q4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

632518:CALOW RS09415
gene id: 632518:CALOW_RS09415
uniprot id: E4Q5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

632518:CALOW RS03635
gene id: 632518:CALOW_RS03635
uniprot id: E4Q5K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

632518:CALOW RS03540
gene id: 632518:CALOW_RS03540
uniprot id: E4Q5I3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

632518:CALOW RS04455
gene id: 632518:CALOW_RS04455
uniprot id: E4Q6F6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

632518:CALOW RS07645
gene id: 632518:CALOW_RS07645
uniprot id: E4Q3B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

632518:CALOW RS05820
gene id: 632518:CALOW_RS05820
uniprot id: E4Q1I7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

632518:CALOW RS02575
gene id: 632518:CALOW_RS02575
uniprot id: E4Q4D7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

632518:CALOW RS05825
gene id: 632518:CALOW_RS05825
uniprot id: E4Q1I8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS11365
gene id: 632518:CALOW_RS11365
uniprot id: E4Q1A2
names: Similarity
messages: Belongs to the ParB family.

632518:CALOW RS06030
gene id: 632518:CALOW_RS06030
uniprot id: E4Q1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

632518:CALOW RS11235
gene id: 632518:CALOW_RS11235
uniprot id: E4Q745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

632518:CALOW RS07350
gene id: 632518:CALOW_RS07350
uniprot id: E4Q2Y7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

632518:CALOW RS03650
gene id: 632518:CALOW_RS03650
uniprot id: E4Q5K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS06325
gene id: 632518:CALOW_RS06325
uniprot id: E4Q204
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS05615
gene id: 632518:CALOW_RS05615
uniprot id: E4Q1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

632518:CALOW RS01400
gene id: 632518:CALOW_RS01400
uniprot id: E4Q342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

632518:CALOW RS02745
gene id: 632518:CALOW_RS02745
uniprot id: E4Q4N9
names: Similarity
messages: Belongs to the RecJ family.

632518:CALOW RS09140
gene id: 632518:CALOW_RS09140
uniprot id: E4Q4Y4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

632518:CALOW RS02810
gene id: 632518:CALOW_RS02810
uniprot id: E4Q4Q2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

632518:CALOW RS01150
gene id: 632518:CALOW_RS01150
uniprot id: E4Q2T2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

632518:CALOW RS04670
gene id: 632518:CALOW_RS04670
uniprot id: E4Q6J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

632518:CALOW RS07695
gene id: 632518:CALOW_RS07695
uniprot id: E4Q3C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

632518:CALOW RS06755
gene id: 632518:CALOW_RS06755
uniprot id: E4Q2F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

632518:CALOW RS00720
gene id: 632518:CALOW_RS00720
uniprot id: E4Q2C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS06915
gene id: 632518:CALOW_RS06915
uniprot id: E4Q2I8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

632518:CALOW RS00355
gene id: 632518:CALOW_RS00355
uniprot id: E4Q1Y3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

632518:CALOW RS06155
gene id: 632518:CALOW_RS06155
uniprot id: E4Q1Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

632518:CALOW RS09575
gene id: 632518:CALOW_RS09575
uniprot id: E4Q5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS02615
gene id: 632518:CALOW_RS02615
uniprot id: E4Q4E5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

632518:CALOW RS03620
gene id: 632518:CALOW_RS03620
uniprot id: E4Q5J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

632518:CALOW RS03260
gene id: 632518:CALOW_RS03260
uniprot id: E4Q558
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

632518:CALOW RS07530
gene id: 632518:CALOW_RS07530
uniprot id: E4Q392
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632518:CALOW RS05830
gene id: 632518:CALOW_RS05830
uniprot id: E4Q1I9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

632518:CALOW RS06850
gene id: 632518:CALOW_RS06850
uniprot id: E4Q2H3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

632518:CALOW RS07945
gene id: 632518:CALOW_RS07945
uniprot id: E4Q3P4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

632518:CALOW RS04655
gene id: 632518:CALOW_RS04655
uniprot id: E4Q6J4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632518:CALOW RS06275
gene id: 632518:CALOW_RS06275
uniprot id: E4Q1Z4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

632518:CALOW RS03875
gene id: 632518:CALOW_RS03875
uniprot id: E4Q5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

632518:CALOW RS09380
gene id: 632518:CALOW_RS09380
uniprot id: E4Q5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

632518:CALOW RS05855
gene id: 632518:CALOW_RS05855
uniprot id: E4Q1J4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS01040
gene id: 632518:CALOW_RS01040
uniprot id: E4Q2R1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

632518:CALOW RS07885
gene id: 632518:CALOW_RS07885
uniprot id: E4Q3N2
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS01620
gene id: 632518:CALOW_RS01620
uniprot id: E4Q3F9
names: Similarity
messages: Belongs to the FGGY kinase family.

632518:CALOW RS09430
gene id: 632518:CALOW_RS09430
uniprot id: E4Q5B8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

632518:CALOW RS08750
gene id: 632518:CALOW_RS08750
uniprot id: E4Q4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

632518:CALOW RS00960
gene id: 632518:CALOW_RS00960
uniprot id: E4Q2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

632518:CALOW RS08720
gene id: 632518:CALOW_RS08720
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS05075
gene id: 632518:CALOW_RS05075
uniprot id: E4Q117
names: Similarity
messages: Belongs to the asp23 family.

632518:CALOW RS07940
gene id: 632518:CALOW_RS07940
uniprot id: E4Q3P3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

632518:CALOW RS05660
gene id: 632518:CALOW_RS05660
uniprot id: E4Q1F8
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS06370
gene id: 632518:CALOW_RS06370
uniprot id: E4Q213
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

632518:CALOW RS10355
gene id: 632518:CALOW_RS10355
uniprot id: E4Q681
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS03755
gene id: 632518:CALOW_RS03755
uniprot id: E4Q5M3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

632518:CALOW RS07075
gene id: 632518:CALOW_RS07075
uniprot id: E4Q2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

632518:CALOW RS09325
gene id: 632518:CALOW_RS09325
uniprot id: E4Q521
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

632518:CALOW RS03865
gene id: 632518:CALOW_RS03865
uniprot id: E4Q5P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

632518:CALOW RS00500
gene id: 632518:CALOW_RS00500
uniprot id: E4Q280
names: Similarity
messages: Belongs to the Fur family.

632518:CALOW RS04995
gene id: 632518:CALOW_RS04995
uniprot id: E4Q6X7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

632518:CALOW RS01310
gene id: 632518:CALOW_RS01310
uniprot id: E4Q324
names: Similarity
messages: Belongs to the phosphopentomutase family.

632518:CALOW RS03295
gene id: 632518:CALOW_RS03295
uniprot id: E4Q565
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

632518:CALOW RS08430
gene id: 632518:CALOW_RS08430
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS10745
gene id: 632518:CALOW_RS10745
uniprot id: E4Q6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

632518:CALOW RS11160
gene id: 632518:CALOW_RS11160
uniprot id: E4Q731
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

632518:CALOW RS07965
gene id: 632518:CALOW_RS07965
uniprot id: E4Q3P8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

632518:CALOW RS02060
gene id: 632518:CALOW_RS02060
uniprot id: E4Q3W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

632518:CALOW RS04375
gene id: 632518:CALOW_RS04375
uniprot id: E4Q6E0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

632518:CALOW RS10380
gene id: 632518:CALOW_RS10380
uniprot id: E4Q686
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS08900
gene id: 632518:CALOW_RS08900
uniprot id: E4Q4M1
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

632518:CALOW RS04850
gene id: 632518:CALOW_RS04850
uniprot id: E4Q6V0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

632518:CALOW RS09200
gene id: 632518:CALOW_RS09200
uniprot id: E4Q4Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

632518:CALOW RS08825
gene id: 632518:CALOW_RS08825
uniprot id: E4Q4K8
names: Similarity
messages: Belongs to the P(II) protein family.

632518:CALOW RS10135
gene id: 632518:CALOW_RS10135
uniprot id: E4Q5W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01500
gene id: 632518:CALOW_RS01500
uniprot id: E4Q361
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

632518:CALOW RS04700
gene id: 632518:CALOW_RS04700
uniprot id: E4Q6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

632518:CALOW RS10385
gene id: 632518:CALOW_RS10385
uniprot id: E4Q687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS02565
gene id: 632518:CALOW_RS02565
uniprot id: E4Q4D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

632518:CALOW RS03150
gene id: 632518:CALOW_RS03150
uniprot id: E4Q536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

632518:CALOW RS05915
gene id: 632518:CALOW_RS05915
uniprot id: E4Q1K6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

632518:CALOW RS08840
gene id: 632518:CALOW_RS08840
uniprot id: E4Q4L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

632518:CALOW RS06575
gene id: 632518:CALOW_RS06575
uniprot id: E4Q249
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

632518:CALOW RS06145
gene id: 632518:CALOW_RS06145
uniprot id: E4Q1Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

632518:CALOW RS07005
gene id: 632518:CALOW_RS07005
uniprot id: E4Q2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

632518:CALOW RS07770
gene id: 632518:CALOW_RS07770
uniprot id: E4Q3E0
names: Similarity
messages: Belongs to the peptidase S41A family.

632518:CALOW RS06545
gene id: 632518:CALOW_RS06545
uniprot id: E4Q243
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

632518:CALOW RS05305
gene id: 632518:CALOW_RS05305
uniprot id: E4Q162
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

632518:CALOW RS02405
gene id: 632518:CALOW_RS02405
uniprot id: E4Q4A2
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

632518:CALOW RS01445
gene id: 632518:CALOW_RS01445
uniprot id: E4Q350
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS03675
gene id: 632518:CALOW_RS03675
uniprot id: E4Q5K8
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS09650
gene id: 632518:CALOW_RS09650
uniprot id: E4Q5F6
names: Similarity
messages: Belongs to the ribulokinase family.

632518:CALOW RS02545
gene id: 632518:CALOW_RS02545
uniprot id: E4Q4D1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

632518:CALOW RS06405
gene id: 632518:CALOW_RS06405
uniprot id: E4Q220
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

632518:CALOW RS03630
gene id: 632518:CALOW_RS03630
uniprot id: E4Q5J9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

632518:CALOW RS02310
gene id: 632518:CALOW_RS02310
uniprot id: E4Q410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS03795
gene id: 632518:CALOW_RS03795
uniprot id: E4Q5N1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

632518:CALOW RS03780
gene id: 632518:CALOW_RS03780
uniprot id: E4Q5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

632518:CALOW RS10130
gene id: 632518:CALOW_RS10130
uniprot id: E4Q5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01360
gene id: 632518:CALOW_RS01360
uniprot id: E4Q334
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

632518:CALOW RS05020
gene id: 632518:CALOW_RS05020
uniprot id: E4Q6Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

632518:CALOW RS02750
gene id: 632518:CALOW_RS02750
uniprot id: E4Q4P0
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS02510
gene id: 632518:CALOW_RS02510
uniprot id: E4Q4C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

632518:CALOW RS04330
gene id: 632518:CALOW_RS04330
uniprot id: E4Q6D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

632518:CALOW RS01215
gene id: 632518:CALOW_RS01215
uniprot id: E4Q311
names: Similarity
messages: Belongs to the ThiD family.

632518:CALOW RS00990
gene id: 632518:CALOW_RS00990
uniprot id: E4Q2Q1
names: Similarity
messages: Belongs to the ComB family.

632518:CALOW RS01605
gene id: 632518:CALOW_RS01605
uniprot id: E4Q3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

632518:CALOW RS11000
gene id: 632518:CALOW_RS11000
uniprot id: E4Q703
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

632518:CALOW RS09010
gene id: 632518:CALOW_RS09010
uniprot id: E4Q4W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

632518:CALOW RS03445
gene id: 632518:CALOW_RS03445
uniprot id: E4Q595
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

632518:CALOW RS06445
gene id: 632518:CALOW_RS06445
uniprot id: E4Q228
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

632518:CALOW RS03765
gene id: 632518:CALOW_RS03765
uniprot id: E4Q5M5
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

632518:CALOW RS06875
gene id: 632518:CALOW_RS06875
uniprot id: E4Q2H9
names: Similarity
messages: Belongs to the thioredoxin family.

632518:CALOW RS02485
gene id: 632518:CALOW_RS02485
uniprot id: E4Q4B8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

632518:CALOW RS03870
gene id: 632518:CALOW_RS03870
uniprot id: E4Q5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

632518:CALOW RS03465
gene id: 632518:CALOW_RS03465
uniprot id: E4Q599
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632518:CALOW RS02275
gene id: 632518:CALOW_RS02275
uniprot id: E4Q403
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS00250
gene id: 632518:CALOW_RS00250
uniprot id: E4Q1W7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

632518:CALOW RS01045
gene id: 632518:CALOW_RS01045
uniprot id: E4Q2R2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

632518:CALOW RS06125
gene id: 632518:CALOW_RS06125
uniprot id: E4Q1P8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

632518:CALOW RS11240
gene id: 632518:CALOW_RS11240
uniprot id: E4Q746
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

632518:CALOW RS04360
gene id: 632518:CALOW_RS04360
uniprot id: E4Q6D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

632518:CALOW RS05640
gene id: 632518:CALOW_RS05640
uniprot id: E4Q1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

632518:CALOW RS05175
gene id: 632518:CALOW_RS05175
uniprot id: E4Q137
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS02365
gene id: 632518:CALOW_RS02365
uniprot id: E4Q494
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS04420
gene id: 632518:CALOW_RS04420
uniprot id: E4Q6E9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS06395
gene id: 632518:CALOW_RS06395
uniprot id: E4Q218
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

632518:CALOW RS10990
gene id: 632518:CALOW_RS10990
uniprot id: E4Q701
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

632518:CALOW RS09275
gene id: 632518:CALOW_RS09275
uniprot id: E4Q511
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

632518:CALOW RS09945
gene id: 632518:CALOW_RS09945
uniprot id: E4Q5T5
names: Similarity
messages: Belongs to the CpsD/CapB family.

632518:CALOW RS08400
gene id: 632518:CALOW_RS08400
uniprot id: E4Q461
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632518:CALOW RS09680
gene id: 632518:CALOW_RS09680
uniprot id: E4Q5G2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

632518:CALOW RS06730
gene id: 632518:CALOW_RS06730
uniprot id: E4Q2F2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

632518:CALOW RS09515
gene id: 632518:CALOW_RS09515
uniprot id: E4Q5D1
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

632518:CALOW RS11425
gene id: 632518:CALOW_RS11425
uniprot id: E4Q1B4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

632518:CALOW RS02560
gene id: 632518:CALOW_RS02560
uniprot id: E4Q4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

632518:CALOW RS06035
gene id: 632518:CALOW_RS06035
uniprot id: E4Q1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

632518:CALOW RS04535
gene id: 632518:CALOW_RS04535
uniprot id: E4Q6H2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

632518:CALOW RS09320
gene id: 632518:CALOW_RS09320
uniprot id: E4Q520
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

632518:CALOW RS05695
gene id: 632518:CALOW_RS05695
uniprot id: E4Q1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

632518:CALOW RS10690
gene id: 632518:CALOW_RS10690
uniprot id: E4Q6M6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

632518:CALOW RS05515
gene id: 632518:CALOW_RS05515
uniprot id: E4Q1C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

632518:CALOW RS07495
gene id: 632518:CALOW_RS07495
uniprot id: E4Q385
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

632518:CALOW RS06665
gene id: 632518:CALOW_RS06665
uniprot id: E4Q2E0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

632518:CALOW RS01835
gene id: 632518:CALOW_RS01835
uniprot id: E4Q3J5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

632518:CALOW RS05100
gene id: 632518:CALOW_RS05100
uniprot id: E4Q122
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

632518:CALOW RS06745
gene id: 632518:CALOW_RS06745
uniprot id: E4Q2F5
names: Similarity
messages: Belongs to the Fur family.

632518:CALOW RS08830
gene id: 632518:CALOW_RS08830
uniprot id: E4Q4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS08705
gene id: 632518:CALOW_RS08705
uniprot id: E4Q4I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

632518:CALOW RS05945
gene id: 632518:CALOW_RS05945
uniprot id: E4Q1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS11340
gene id: 632518:CALOW_RS11340
uniprot id: E4Q197
names: Similarity
messages: Belongs to the class-I fumarase family.

632518:CALOW RS10585
gene id: 632518:CALOW_RS10585
uniprot id: E4Q6K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS00570
gene id: 632518:CALOW_RS00570
uniprot id: E4Q294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS05125
gene id: 632518:CALOW_RS05125
uniprot id: E4Q127
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

632518:CALOW RS00050
gene id: 632518:CALOW_RS00050
uniprot id: E4Q1T1
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS08815
gene id: 632518:CALOW_RS08815
uniprot id: E4Q4K6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

632518:CALOW RS06950
gene id: 632518:CALOW_RS06950
uniprot id: E4Q2J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS04500
gene id: 632518:CALOW_RS04500
uniprot id: E4Q6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

632518:CALOW RS10410
gene id: 632518:CALOW_RS10410
uniprot id: E4Q692
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

632518:CALOW RS08265
gene id: 632518:CALOW_RS08265
uniprot id: E4Q435
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

632518:CALOW RS04565
gene id: 632518:CALOW_RS04565
uniprot id: E4Q6H8
names: Similarity
messages: Belongs to the HypD family.

632518:CALOW RS03775
gene id: 632518:CALOW_RS03775
uniprot id: E4Q5M7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

632518:CALOW RS10500
gene id: 632518:CALOW_RS10500
uniprot id: E4Q6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

632518:CALOW RS10845
gene id: 632518:CALOW_RS10845
uniprot id: E4Q6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

632518:CALOW RS07095
gene id: 632518:CALOW_RS07095
uniprot id: E4Q2U5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

632518:CALOW RS06490
gene id: 632518:CALOW_RS06490
uniprot id: E4Q232
names: Similarity
messages: Belongs to the UPF0047 family.

632518:CALOW RS08780
gene id: 632518:CALOW_RS08780
uniprot id: E4Q4J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

632518:CALOW RS10785
gene id: 632518:CALOW_RS10785
uniprot id: E4Q6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

632518:CALOW RS09520
gene id: 632518:CALOW_RS09520
uniprot id: E4Q5D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

632518:CALOW RS08450
gene id: 632518:CALOW_RS08450
uniprot id: E4Q471
names: Similarity
messages: Belongs to the GerABKA family.

632518:CALOW RS00415
gene id: 632518:CALOW_RS00415
uniprot id: E4Q265
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

632518:CALOW RS04650
gene id: 632518:CALOW_RS04650
uniprot id: E4Q4M1
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

632518:CALOW RS07860
gene id: 632518:CALOW_RS07860
uniprot id: E4Q3M7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

632518:CALOW RS01060
gene id: 632518:CALOW_RS01060
uniprot id: E4Q2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

632518:CALOW RS02670
gene id: 632518:CALOW_RS02670
uniprot id: E4Q4F6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

632518:CALOW RS06705
gene id: 632518:CALOW_RS06705
uniprot id: E4Q2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

632518:CALOW RS09835
gene id: 632518:CALOW_RS09835
uniprot id: E4Q5R6
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS04760
gene id: 632518:CALOW_RS04760
uniprot id: E4Q6T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

632518:CALOW RS05780
gene id: 632518:CALOW_RS05780
uniprot id: E4Q1H9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

632518:CALOW RS03210
gene id: 632518:CALOW_RS03210
uniprot id: E4Q548
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

632518:CALOW RS04545
gene id: 632518:CALOW_RS04545
uniprot id: E4Q6H4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

632518:CALOW RS03550
gene id: 632518:CALOW_RS03550
uniprot id: E4Q5I5
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS04845
gene id: 632518:CALOW_RS04845
uniprot id: E4Q6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

632518:CALOW RS06830
gene id: 632518:CALOW_RS06830
uniprot id: E4Q2G9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

632518:CALOW RS06040
gene id: 632518:CALOW_RS06040
uniprot id: E4Q1N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632518:CALOW RS04345
gene id: 632518:CALOW_RS04345
uniprot id: E4Q6D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

632518:CALOW RS04395
gene id: 632518:CALOW_RS04395
uniprot id: E4Q6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

632518:CALOW RS02175
gene id: 632518:CALOW_RS02175
uniprot id: E4Q3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

632518:CALOW RS07185
gene id: 632518:CALOW_RS07185
uniprot id: E4Q2W1
names: Similarity
messages: Belongs to the TrpF family.

632518:CALOW RS11410
gene id: 632518:CALOW_RS11410
uniprot id: E4Q1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

632518:CALOW RS05510
gene id: 632518:CALOW_RS05510
uniprot id: E4Q1C7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

632518:CALOW RS06555
gene id: 632518:CALOW_RS06555
uniprot id: E4Q245
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

632518:CALOW RS05505
gene id: 632518:CALOW_RS05505
uniprot id: E4Q1C6
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

632518:CALOW RS03960
gene id: 632518:CALOW_RS03960
uniprot id: E4Q5Y5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS08735
gene id: 632518:CALOW_RS08735
uniprot id: E4Q4I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

632518:CALOW RS08175
gene id: 632518:CALOW_RS08175
uniprot id: E4Q417
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

632518:CALOW RS09600
gene id: 632518:CALOW_RS09600
uniprot id: E4Q5E6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

632518:CALOW RS09560
gene id: 632518:CALOW_RS09560
uniprot id: E4Q5D9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

632518:CALOW RS04270
gene id: 632518:CALOW_RS04270
uniprot id: E4Q644
names: Similarity
messages: Belongs to the RemA family.

632518:CALOW RS11380
gene id: 632518:CALOW_RS11380
uniprot id: E4Q1A5
names: Similarity
messages: Belongs to the alkaline phosphatase family.

632518:CALOW RS10125
gene id: 632518:CALOW_RS10125
uniprot id: E4Q5W6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632518:CALOW RS07375
gene id: 632518:CALOW_RS07375
uniprot id: E4Q2Z2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

632518:CALOW RS03170
gene id: 632518:CALOW_RS03170
uniprot id: E4Q540
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632518:CALOW RS01025
gene id: 632518:CALOW_RS01025
uniprot id: E4Q2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

632518:CALOW RS03435
gene id: 632518:CALOW_RS03435
uniprot id: E4Q593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

632518:CALOW RS03860
gene id: 632518:CALOW_RS03860
uniprot id: E4Q5P4
names: Similarity
messages: Belongs to the CinA family.

632518:CALOW RS00185
gene id: 632518:CALOW_RS00185
uniprot id: E4Q1V6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS10590
gene id: 632518:CALOW_RS10590
uniprot id: E4Q6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS09235
gene id: 632518:CALOW_RS09235
uniprot id: E4Q503
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

632518:CALOW RS04805
gene id: 632518:CALOW_RS04805
uniprot id: E4Q6U0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

632518:CALOW RS05655
gene id: 632518:CALOW_RS05655
uniprot id: E4Q1F7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS02985
gene id: 632518:CALOW_RS02985
uniprot id: E4Q4T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

632518:CALOW RS10535
gene id: 632518:CALOW_RS10535
uniprot id: E4Q6B7
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS05035
gene id: 632518:CALOW_RS05035
uniprot id: E4Q6Y5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

632518:CALOW RS09060
gene id: 632518:CALOW_RS09060
uniprot id: E4Q4X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632518:CALOW RS06970
gene id: 632518:CALOW_RS06970
uniprot id: E4Q2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

632518:CALOW RS03130
gene id: 632518:CALOW_RS03130
uniprot id: E4Q532
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS00290
gene id: 632518:CALOW_RS00290
uniprot id: E4Q1X4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632518:CALOW RS07420
gene id: 632518:CALOW_RS07420
uniprot id: E4Q370
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

632518:CALOW RS11385
gene id: 632518:CALOW_RS11385
uniprot id: E4Q1A6
names: Similarity
messages: Belongs to the ParB family.

632518:CALOW RS02285
gene id: 632518:CALOW_RS02285
uniprot id: E4Q405
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

632518:CALOW RS01190
gene id: 632518:CALOW_RS01190
uniprot id: E4Q306
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

632518:CALOW RS02585
gene id: 632518:CALOW_RS02585
uniprot id: E4Q4D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

632518:CALOW RS04340
gene id: 632518:CALOW_RS04340
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS09310
gene id: 632518:CALOW_RS09310
uniprot id: E4Q518
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS05665
gene id: 632518:CALOW_RS05665
uniprot id: E4Q1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

632518:CALOW RS04885
gene id: 632518:CALOW_RS04885
uniprot id: E4Q6V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

632518:CALOW RS05955
gene id: 632518:CALOW_RS05955
uniprot id: E4Q1L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

632518:CALOW RS00630
gene id: 632518:CALOW_RS00630
uniprot id: E4Q2A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

632518:CALOW RS01795
gene id: 632518:CALOW_RS01795
uniprot id: E4Q3I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

632518:CALOW RS06630
gene id: 632518:CALOW_RS06630
uniprot id: E4Q257
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

632518:CALOW RS05300
gene id: 632518:CALOW_RS05300
uniprot id: E4Q161
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

632518:CALOW RS04860
gene id: 632518:CALOW_RS04860
uniprot id: E4Q6V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

632518:CALOW RS03950
gene id: 632518:CALOW_RS03950
uniprot id: E4Q5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

632518:CALOW RS08165
gene id: 632518:CALOW_RS08165
uniprot id: E4Q3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

632518:CALOW RS09245
gene id: 632518:CALOW_RS09245
uniprot id: E4Q505
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

632518:CALOW RS06675
gene id: 632518:CALOW_RS06675
uniprot id: E4Q2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

632518:CALOW RS06565
gene id: 632518:CALOW_RS06565
uniprot id: E4Q247
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

632518:CALOW RS05710
gene id: 632518:CALOW_RS05710
uniprot id: E4Q1G8
names: Subcellular Location Annotation
messages: Cytoplasm

632518:CALOW RS02370
gene id: 632518:CALOW_RS02370
uniprot id: E4Q495
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS05500
gene id: 632518:CALOW_RS05500
uniprot id: E4Q1C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

632518:CALOW RS10770
gene id: 632518:CALOW_RS10770
uniprot id: E4Q6P0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS03530
gene id: 632518:CALOW_RS03530
uniprot id: E4Q5I1
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

632518:CALOW RS05365
gene id: 632518:CALOW_RS05365
uniprot id: E4Q174
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

632518:CALOW RS05875
gene id: 632518:CALOW_RS05875
uniprot id: E4Q1J8
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS00245
gene id: 632518:CALOW_RS00245
uniprot id: E4Q1W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

632518:CALOW RS02345
gene id: 632518:CALOW_RS02345
uniprot id: E4Q490
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

632518:CALOW RS02730
gene id: 632518:CALOW_RS02730
uniprot id: E4Q4N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

632518:CALOW RS09760
gene id: 632518:CALOW_RS09760
uniprot id: E4Q5Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632518:CALOW RS06410
gene id: 632518:CALOW_RS06410
uniprot id: E4Q221
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

632518:CALOW RS05240
gene id: 632518:CALOW_RS05240
uniprot id: E4Q149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

632518:CALOW RS03745
gene id: 632518:CALOW_RS03745
uniprot id: E4Q5M1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

632518:CALOW RS01370
gene id: 632518:CALOW_RS01370
uniprot id: E4Q336
names: Similarity
messages: Belongs to the sigma-70 factor family.

632518:CALOW RS05520
gene id: 632518:CALOW_RS05520
uniprot id: E4Q1C9
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS04790
gene id: 632518:CALOW_RS04790
uniprot id: E4Q6T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

632518:CALOW RS04290
gene id: 632518:CALOW_RS04290
uniprot id: E4Q6C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

632518:CALOW RS00845
gene id: 632518:CALOW_RS00845
uniprot id: E4Q2M2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632518:CALOW RS11525
gene id: 632518:CALOW_RS11525
uniprot id: E4Q5G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632518:CALOW RS06780
gene id: 632518:CALOW_RS06780
uniprot id: E4Q2G0
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS08375
gene id: 632518:CALOW_RS08375
uniprot id: E4Q456
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

632518:CALOW RS03770
gene id: 632518:CALOW_RS03770
uniprot id: E4Q5M6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

632518:CALOW RS05230
gene id: 632518:CALOW_RS05230
uniprot id: E4Q147
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

632518:CALOW RS06615
gene id: 632518:CALOW_RS06615
uniprot id: E4Q254
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS05385
gene id: 632518:CALOW_RS05385
uniprot id: E4Q178
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

632518:CALOW RS03730
gene id: 632518:CALOW_RS03730
uniprot id: E4Q5L8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

632518:CALOW RS08215
gene id: 632518:CALOW_RS08215
uniprot id: E4Q425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS00195
gene id: 632518:CALOW_RS00195
uniprot id: E4Q1V8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632518:CALOW RS10795
gene id: 632518:CALOW_RS10795
uniprot id: E4Q6P4
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

632518:CALOW RS03585
gene id: 632518:CALOW_RS03585
uniprot id: E4Q5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS03270
gene id: 632518:CALOW_RS03270
uniprot id: E4Q560
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

632518:CALOW RS10360
gene id: 632518:CALOW_RS10360
uniprot id: E4Q682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01000
gene id: 632518:CALOW_RS01000
uniprot id: E4Q2Q3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS08570
gene id: 632518:CALOW_RS08570
uniprot id: E4Q4G6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632518:CALOW RS00735
gene id: 632518:CALOW_RS00735
uniprot id: E4Q2C7
names: Similarity
messages: Belongs to the DHPS family.

632518:CALOW RS05450
gene id: 632518:CALOW_RS05450
uniprot id: E4Q190
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

632518:CALOW RS04965
gene id: 632518:CALOW_RS04965
uniprot id: E4Q6X1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

632518:CALOW RS06385
gene id: 632518:CALOW_RS06385
uniprot id: E4Q216
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

632518:CALOW RS06135
gene id: 632518:CALOW_RS06135
uniprot id: E4Q1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

632518:CALOW RS03845
gene id: 632518:CALOW_RS03845
uniprot id: E4Q5P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

632518:CALOW RS04890
gene id: 632518:CALOW_RS04890
uniprot id: E4Q6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

632518:CALOW RS00585
gene id: 632518:CALOW_RS00585
uniprot id: E4Q297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS03725
gene id: 632518:CALOW_RS03725
uniprot id: E4Q5L7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

632518:CALOW RS10445
gene id: 632518:CALOW_RS10445
uniprot id: E4Q699
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632518:CALOW RS09425
gene id: 632518:CALOW_RS09425
uniprot id: E4Q5B7
names: Similarity
messages: Belongs to the DprA/Smf family.

632518:CALOW RS05395
gene id: 632518:CALOW_RS05395
uniprot id: E4Q180
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

632518:CALOW RS11230
gene id: 632518:CALOW_RS11230
uniprot id: E4Q744
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS06605
gene id: 632518:CALOW_RS06605
uniprot id: E4Q253
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

632518:CALOW RS03095
gene id: 632518:CALOW_RS03095
uniprot id: E4Q4V0
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS02825
gene id: 632518:CALOW_RS02825
uniprot id: E4Q4Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

632518:CALOW RS11815
gene id: 632518:CALOW_RS11815
uniprot id: E4Q1B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

632518:CALOW RS05185
gene id: 632518:CALOW_RS05185
uniprot id: E4Q139
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

632518:CALOW RS04770
gene id: 632518:CALOW_RS04770
uniprot id: E4Q6T3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS07260
gene id: 632518:CALOW_RS07260
uniprot id: E4Q2X6
names: Subcellular Location Annotation
messages: Membrane

632518:CALOW RS00090
gene id: 632518:CALOW_RS00090
uniprot id: E4Q1T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

632518:CALOW RS03085
gene id: 632518:CALOW_RS03085
uniprot id: E4Q4U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

632518:CALOW RS04440
gene id: 632518:CALOW_RS04440
uniprot id: E4Q6F3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632518:CALOW RS07490
gene id: 632518:CALOW_RS07490
uniprot id: E4Q384
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

632518:CALOW RS09800
gene id: 632518:CALOW_RS09800
uniprot id: E4Q5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS07365
gene id: 632518:CALOW_RS07365
uniprot id: E4Q2Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

632518:CALOW RS10680
gene id: 632518:CALOW_RS10680
uniprot id: E4Q6M4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

632518:CALOW RS03850
gene id: 632518:CALOW_RS03850
uniprot id: E4Q5P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

632518:CALOW RS05220
gene id: 632518:CALOW_RS05220
uniprot id: E4Q145
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

632518:CALOW RS10570
gene id: 632518:CALOW_RS10570
uniprot id: E4Q6K2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

632518:CALOW RS00765
gene id: 632518:CALOW_RS00765
uniprot id: E4Q2D3
names: Similarity
messages: Belongs to the PspA/IM30 family.

632518:CALOW RS02700
gene id: 632518:CALOW_RS02700
uniprot id: E4Q4G2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS10440
gene id: 632518:CALOW_RS10440
uniprot id: E4Q698
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

632518:CALOW RS06250
gene id: 632518:CALOW_RS06250
uniprot id: E4Q1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

632518:CALOW RS09360
gene id: 632518:CALOW_RS09360
uniprot id: E4Q5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS01815
gene id: 632518:CALOW_RS01815
uniprot id: E4Q3J1
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS03520
gene id: 632518:CALOW_RS03520
uniprot id: E4Q152
names: Similarity
messages: Belongs to the UPF0236 family.

632518:CALOW RS09445
gene id: 632518:CALOW_RS09445
uniprot id: E4Q5C1
names: Similarity
messages: Belongs to the Fur family.

632518:CALOW RS07480
gene id: 632518:CALOW_RS07480
uniprot id: E4Q382
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

632518:CALOW RS09115
gene id: 632518:CALOW_RS09115
uniprot id: E4Q4X9
names: Similarity
messages: Belongs to the UPF0237 family.

632518:CALOW RS09015
gene id: 632518:CALOW_RS09015
uniprot id: E4Q4W1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

632518:CALOW RS06320
gene id: 632518:CALOW_RS06320
uniprot id: E4Q203
names: Similarity
messages: Belongs to the UPF0111 family.

632518:CALOW RS03510
gene id: 632518:CALOW_RS03510
uniprot id: E4Q5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS07150
gene id: 632518:CALOW_RS07150
uniprot id: E4Q2V4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS04435
gene id: 632518:CALOW_RS04435
uniprot id: E4Q6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

632518:CALOW RS06710
gene id: 632518:CALOW_RS06710
uniprot id: E4Q2E9
names: Similarity
messages: Belongs to the CapA family.

632518:CALOW RS06700
gene id: 632518:CALOW_RS06700
uniprot id: E4Q2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632518:CALOW RS00610
gene id: 632518:CALOW_RS00610
uniprot id: E4Q2A2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632518:CALOW RS07895
gene id: 632518:CALOW_RS07895
uniprot id: E4Q3N4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

632518:CALOW RS06635
gene id: 632518:CALOW_RS06635
uniprot id: E4Q258
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632518:CALOW RS09280
gene id: 632518:CALOW_RS09280
uniprot id: E4Q512
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

632518:CALOW RS01120
gene id: 632518:CALOW_RS01120
uniprot id: E4Q2S6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

632518:CALOW RS07310
gene id: 632518:CALOW_RS07310
uniprot id: E4Q2Y1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.