632335:CALKR RS02395
gene id: 632335:CALKR_RS02395
uniprot id: E4S9H7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS13060
gene id: 632335:CALKR_RS13060
uniprot id: E4S941
names: Similarity
messages: Belongs to the ParB family.

632335:CALKR RS07325
gene id: 632335:CALKR_RS07325
uniprot id: E4S9A6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

632335:CALKR RS08055
gene id: 632335:CALKR_RS08055
uniprot id: E4SA21
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

632335:CALKR RS06575
gene id: 632335:CALKR_RS06575
uniprot id: E4S7T8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

632335:CALKR RS12375
gene id: 632335:CALKR_RS12375
uniprot id: E4S8D7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS01170
gene id: 632335:CALKR_RS01170
uniprot id: E4S7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

632335:CALKR RS08955
gene id: 632335:CALKR_RS08955
uniprot id: E4SAV3
names: Similarity
messages: Belongs to the leucine-binding protein family.

632335:CALKR RS10440
gene id: 632335:CALKR_RS10440
uniprot id: E4S5B8
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

632335:CALKR RS04560
gene id: 632335:CALKR_RS04560
uniprot id: E4S4R6
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS12200
gene id: 632335:CALKR_RS12200
uniprot id: E4S7Y6
names: Similarity
messages: Belongs to the CpsD/CapB family.

632335:CALKR RS00735
gene id: 632335:CALKR_RS00735
uniprot id: E4S6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

632335:CALKR RS02935
gene id: 632335:CALKR_RS02935
uniprot id: E4S9Z4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

632335:CALKR RS10955
gene id: 632335:CALKR_RS10955
uniprot id: E4S692
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS02255
gene id: 632335:CALKR_RS02255
uniprot id: E4S980
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

632335:CALKR RS08130
gene id: 632335:CALKR_RS08130
uniprot id: E4SA35
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

632335:CALKR RS07065
gene id: 632335:CALKR_RS07065
uniprot id: E4S8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

632335:CALKR RS05605
gene id: 632335:CALKR_RS05605
uniprot id: E4S6M0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

632335:CALKR RS04705
gene id: 632335:CALKR_RS04705
uniprot id: E4S506
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632335:CALKR RS06120
gene id: 632335:CALKR_RS06120
uniprot id: E4S775
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS00030
gene id: 632335:CALKR_RS00030
uniprot id: E4S5D9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

632335:CALKR RS09625
gene id: 632335:CALKR_RS09625
uniprot id: E4S4J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

632335:CALKR RS07455
gene id: 632335:CALKR_RS07455
uniprot id: E4S9D0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

632335:CALKR RS05285
gene id: 632335:CALKR_RS05285
uniprot id: E4S5P6
names: Similarity
messages: Belongs to the MotB family.

632335:CALKR RS07055
gene id: 632335:CALKR_RS07055
uniprot id: E4S8S5
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

632335:CALKR RS00825
gene id: 632335:CALKR_RS00825
uniprot id: E4S6H6
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

632335:CALKR RS05275
gene id: 632335:CALKR_RS05275
uniprot id: E4S5P4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

632335:CALKR RS10980
gene id: 632335:CALKR_RS10980
uniprot id: E4S697
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632335:CALKR RS02950
gene id: 632335:CALKR_RS02950
uniprot id: E4S9Z7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS07950
gene id: 632335:CALKR_RS07950
uniprot id: E4S9U2
names: Similarity
messages: Belongs to the Fur family.

632335:CALKR RS08765
gene id: 632335:CALKR_RS08765
uniprot id: E4SAR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

632335:CALKR RS02900
gene id: 632335:CALKR_RS02900
uniprot id: E4S9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

632335:CALKR RS01600
gene id: 632335:CALKR_RS01600
uniprot id: E4S839
names: Similarity
messages: Belongs to the ThiD family.

632335:CALKR RS11990
gene id: 632335:CALKR_RS11990
uniprot id: E4S7U5
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS02365
gene id: 632335:CALKR_RS02365
uniprot id: E4S9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

632335:CALKR RS07235
gene id: 632335:CALKR_RS07235
uniprot id: E4S8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

632335:CALKR RS02325
gene id: 632335:CALKR_RS02325
uniprot id: E4S994
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

632335:CALKR RS03270
gene id: 632335:CALKR_RS03270
uniprot id: E4SAB8
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS04315
gene id: 632335:CALKR_RS04315
uniprot id: E4S4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

632335:CALKR RS03265
gene id: 632335:CALKR_RS03265
uniprot id: E4SAB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS06150
gene id: 632335:CALKR_RS06150
uniprot id: E4S781
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

632335:CALKR RS02555
gene id: 632335:CALKR_RS02555
uniprot id: E4S9K9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

632335:CALKR RS08295
gene id: 632335:CALKR_RS08295
uniprot id: E4SA67
names: Subcellular Location Annotation
messages: Cell membrane

632335:CALKR RS10965
gene id: 632335:CALKR_RS10965
uniprot id: E4S694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS09955
gene id: 632335:CALKR_RS09955
uniprot id: E4S4V6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

632335:CALKR RS06005
gene id: 632335:CALKR_RS06005
uniprot id: E4S752
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

632335:CALKR RS11805
gene id: 632335:CALKR_RS11805
uniprot id: E4S7C6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

632335:CALKR RS03625
gene id: 632335:CALKR_RS03625
uniprot id: E4SAP4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

632335:CALKR RS07555
gene id: 632335:CALKR_RS07555
uniprot id: E4S9E8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS02965
gene id: 632335:CALKR_RS02965
uniprot id: E4SA00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

632335:CALKR RS11050
gene id: 632335:CALKR_RS11050
uniprot id: E4S6B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

632335:CALKR RS04410
gene id: 632335:CALKR_RS04410
uniprot id: E4S4N6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

632335:CALKR RS02755
gene id: 632335:CALKR_RS02755
uniprot id: E4S9W0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS08810
gene id: 632335:CALKR_RS08810
uniprot id: E4SAS4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

632335:CALKR RS07150
gene id: 632335:CALKR_RS07150
uniprot id: E4S8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

632335:CALKR RS07830
gene id: 632335:CALKR_RS07830
uniprot id: E4S9R9
names: Similarity
messages: Belongs to the asparagine synthetase family.

632335:CALKR RS07910
gene id: 632335:CALKR_RS07910
uniprot id: E4S9T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

632335:CALKR RS07095
gene id: 632335:CALKR_RS07095
uniprot id: E4S8T3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

632335:CALKR RS07110
gene id: 632335:CALKR_RS07110
uniprot id: E4S8T6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS06075
gene id: 632335:CALKR_RS06075
uniprot id: E4S766
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS02585
gene id: 632335:CALKR_RS02585
uniprot id: E4S9L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

632335:CALKR RS05685
gene id: 632335:CALKR_RS05685
uniprot id: E4S6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

632335:CALKR RS09495
gene id: 632335:CALKR_RS09495
uniprot id: E4S4H2
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS12600
gene id: 632335:CALKR_RS12600
uniprot id: E4S8I0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

632335:CALKR RS01325
gene id: 632335:CALKR_RS01325
uniprot id: E4S7I7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS12510
gene id: 632335:CALKR_RS12510
uniprot id: E4S8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

632335:CALKR RS00945
gene id: 632335:CALKR_RS00945
uniprot id: E4S6K1
names: Similarity
messages: Belongs to the DHPS family.

632335:CALKR RS09865
gene id: 632335:CALKR_RS09865
uniprot id: E4S4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

632335:CALKR RS11120
gene id: 632335:CALKR_RS11120
uniprot id: E4S6C4
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

632335:CALKR RS05875
gene id: 632335:CALKR_RS05875
uniprot id: E4S6S5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

632335:CALKR RS09490
gene id: 632335:CALKR_RS09490
uniprot id: E4S4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

632335:CALKR RS08410
gene id: 632335:CALKR_RS08410
uniprot id: E4SAF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

632335:CALKR RS04370
gene id: 632335:CALKR_RS04370
uniprot id: E4S4M8
names: Similarity
messages: Belongs to the peptidase S41A family.

632335:CALKR RS02540
gene id: 632335:CALKR_RS02540
uniprot id: E4S9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS07550
gene id: 632335:CALKR_RS07550
uniprot id: E4S9E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS00590
gene id: 632335:CALKR_RS00590
uniprot id: E4S622
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

632335:CALKR RS00810
gene id: 632335:CALKR_RS00810
uniprot id: E4S6H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS06950
gene id: 632335:CALKR_RS06950
uniprot id: E4S8C8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS02470
gene id: 632335:CALKR_RS02470
uniprot id: E4S9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS10675
gene id: 632335:CALKR_RS10675
uniprot id: E4S5T6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

632335:CALKR RS00005
gene id: 632335:CALKR_RS00005
uniprot id: E4S5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

632335:CALKR RS07320
gene id: 632335:CALKR_RS07320
uniprot id: E4S9A5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS06895
gene id: 632335:CALKR_RS06895
uniprot id: E4S8B7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

632335:CALKR RS12960
gene id: 632335:CALKR_RS12960
uniprot id: E4S921
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632335:CALKR RS05775
gene id: 632335:CALKR_RS05775
uniprot id: E4S6Q5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS01990
gene id: 632335:CALKR_RS01990
uniprot id: E4S8P2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

632335:CALKR RS00355
gene id: 632335:CALKR_RS00355
uniprot id: E4S5J0
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

632335:CALKR RS05375
gene id: 632335:CALKR_RS05375
uniprot id: E4S645
names: Similarity
messages: Belongs to the HupF/HypC family.

632335:CALKR RS06855
gene id: 632335:CALKR_RS06855
uniprot id: E4S8A9
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS05110
gene id: 632335:CALKR_RS05110
uniprot id: E4S5L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

632335:CALKR RS00795
gene id: 632335:CALKR_RS00795
uniprot id: E4S6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS07385
gene id: 632335:CALKR_RS07385
uniprot id: E4S9B8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

632335:CALKR RS07310
gene id: 632335:CALKR_RS07310
uniprot id: E4S9A3
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS08265
gene id: 632335:CALKR_RS08265
uniprot id: E4SA61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

632335:CALKR RS01935
gene id: 632335:CALKR_RS01935
uniprot id: E4S8N1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

632335:CALKR RS01365
gene id: 632335:CALKR_RS01365
uniprot id: E4S7J6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

632335:CALKR RS09690
gene id: 632335:CALKR_RS09690
uniprot id: E4S4L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS13055
gene id: 632335:CALKR_RS13055
uniprot id: E4S940
names: Similarity
messages: Belongs to the alkaline phosphatase family.

632335:CALKR RS02610
gene id: 632335:CALKR_RS02610
uniprot id: E4S9M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

632335:CALKR RS08650
gene id: 632335:CALKR_RS08650
uniprot id: E4SAJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS07890
gene id: 632335:CALKR_RS07890
uniprot id: E4S9T1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

632335:CALKR RS11285
gene id: 632335:CALKR_RS11285
uniprot id: E4S6T1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

632335:CALKR RS09025
gene id: 632335:CALKR_RS09025
uniprot id: E4SAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS09530
gene id: 632335:CALKR_RS09530
uniprot id: E4S4H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

632335:CALKR RS02020
gene id: 632335:CALKR_RS02020
uniprot id: E4S8P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

632335:CALKR RS08435
gene id: 632335:CALKR_RS08435
uniprot id: E4SAF5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

632335:CALKR RS04090
gene id: 632335:CALKR_RS04090
uniprot id: E4S4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

632335:CALKR RS13165
gene id: 632335:CALKR_RS13165
uniprot id: E4SAY6
names: Similarity
messages: Belongs to the Nth/MutY family.

632335:CALKR RS11105
gene id: 632335:CALKR_RS11105
uniprot id: E4S6C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

632335:CALKR RS03090
gene id: 632335:CALKR_RS03090
uniprot id: E4SA88
names: Similarity
messages: Belongs to the NadC/ModD family.

632335:CALKR RS02570
gene id: 632335:CALKR_RS02570
uniprot id: E4S9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

632335:CALKR RS07080
gene id: 632335:CALKR_RS07080
uniprot id: E4S8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

632335:CALKR RS03845
gene id: 632335:CALKR_RS03845
uniprot id: E4S3Z4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

632335:CALKR RS06105
gene id: 632335:CALKR_RS06105
uniprot id: E4S772
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

632335:CALKR RS05570
gene id: 632335:CALKR_RS05570
uniprot id: E4S6L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS06435
gene id: 632335:CALKR_RS06435
uniprot id: E4S7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

632335:CALKR RS11440
gene id: 632335:CALKR_RS11440
uniprot id: E4S6V9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

632335:CALKR RS00315
gene id: 632335:CALKR_RS00315
uniprot id: E4S5I2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

632335:CALKR RS04275
gene id: 632335:CALKR_RS04275
uniprot id: E4S4E1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

632335:CALKR RS08340
gene id: 632335:CALKR_RS08340
uniprot id: E4SAD6
names: Similarity
messages: Belongs to the SecB family.

632335:CALKR RS04775
gene id: 632335:CALKR_RS04775
uniprot id: E4S520
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

632335:CALKR RS02390
gene id: 632335:CALKR_RS02390
uniprot id: E4S9H6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS06395
gene id: 632335:CALKR_RS06395
uniprot id: E4S7Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

632335:CALKR RS05370
gene id: 632335:CALKR_RS05370
uniprot id: E4S644
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

632335:CALKR RS10520
gene id: 632335:CALKR_RS10520
uniprot id: E4S5Q7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS02385
gene id: 632335:CALKR_RS02385
uniprot id: E4S9H5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS03620
gene id: 632335:CALKR_RS03620
uniprot id: E4SAP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

632335:CALKR RS01695
gene id: 632335:CALKR_RS01695
uniprot id: E4S853
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

632335:CALKR RS09070
gene id: 632335:CALKR_RS09070
uniprot id: E4SAX5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

632335:CALKR RS09735
gene id: 632335:CALKR_RS09735
uniprot id: E4S4L9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

632335:CALKR RS08740
gene id: 632335:CALKR_RS08740
uniprot id: E4SAR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

632335:CALKR RS09650
gene id: 632335:CALKR_RS09650
uniprot id: E4S4K2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632335:CALKR RS09290
gene id: 632335:CALKR_RS09290
uniprot id: E4S467
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632335:CALKR RS04465
gene id: 632335:CALKR_RS04465
uniprot id: E4S4P7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS05090
gene id: 632335:CALKR_RS05090
uniprot id: E4S5K7
names: Similarity
messages: Belongs to the RemA family.

632335:CALKR RS01615
gene id: 632335:CALKR_RS01615
uniprot id: E4S842
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

632335:CALKR RS09125
gene id: 632335:CALKR_RS09125
uniprot id: E4S440
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

632335:CALKR RS07785
gene id: 632335:CALKR_RS07785
uniprot id: E4S9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

632335:CALKR RS00015
gene id: 632335:CALKR_RS00015
uniprot id: E4S5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

632335:CALKR RS08695
gene id: 632335:CALKR_RS08695
uniprot id: E4SAJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

632335:CALKR RS08515
gene id: 632335:CALKR_RS08515
uniprot id: E4SAG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

632335:CALKR RS02370
gene id: 632335:CALKR_RS02370
uniprot id: E4S9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

632335:CALKR RS08155
gene id: 632335:CALKR_RS08155
uniprot id: E4SA40
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

632335:CALKR RS07715
gene id: 632335:CALKR_RS07715
uniprot id: E4S9P9
names: Similarity
messages: Belongs to the peptidase S16 family.

632335:CALKR RS08690
gene id: 632335:CALKR_RS08690
uniprot id: E4SAJ6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

632335:CALKR RS02125
gene id: 632335:CALKR_RS02125
uniprot id: E4S955
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

632335:CALKR RS04915
gene id: 632335:CALKR_RS04915
uniprot id: E4S548
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

632335:CALKR RS05365
gene id: 632335:CALKR_RS05365
uniprot id: E4S643
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

632335:CALKR RS11060
gene id: 632335:CALKR_RS11060
uniprot id: E4S6B3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

632335:CALKR RS00930
gene id: 632335:CALKR_RS00930
uniprot id: E4S6J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS12445
gene id: 632335:CALKR_RS12445
uniprot id: E4S8F2
names: Similarity
messages: Belongs to the peptidase S24 family.

632335:CALKR RS03045
gene id: 632335:CALKR_RS03045
uniprot id: E4SA80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

632335:CALKR RS05655
gene id: 632335:CALKR_RS05655
uniprot id: E4S6N1
names: Similarity
messages: Belongs to the fabD family.

632335:CALKR RS04320
gene id: 632335:CALKR_RS04320
uniprot id: E4S4F0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

632335:CALKR RS00865
gene id: 632335:CALKR_RS00865
uniprot id: E4S6I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS08490
gene id: 632335:CALKR_RS08490
uniprot id: E4SAG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS07855
gene id: 632335:CALKR_RS07855
uniprot id: E4S9S4
names: Similarity
messages: Belongs to the peptidase M29 family.

632335:CALKR RS08505
gene id: 632335:CALKR_RS08505
uniprot id: E4SAG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632335:CALKR RS12520
gene id: 632335:CALKR_RS12520
uniprot id: E4S8G5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS06910
gene id: 632335:CALKR_RS06910
uniprot id: E4S8C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Monomer.

632335:CALKR RS05330
gene id: 632335:CALKR_RS05330
uniprot id: E4S5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

632335:CALKR RS09610
gene id: 632335:CALKR_RS09610
uniprot id: E4S4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

632335:CALKR RS05940
gene id: 632335:CALKR_RS05940
uniprot id: E4S739
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

632335:CALKR RS02850
gene id: 632335:CALKR_RS02850
uniprot id: E4S9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS09465
gene id: 632335:CALKR_RS09465
uniprot id: E4S4G6
names: Similarity
messages: Belongs to the AOR/FOR family.

632335:CALKR RS09305
gene id: 632335:CALKR_RS09305
uniprot id: E4S470
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

632335:CALKR RS06180
gene id: 632335:CALKR_RS06180
uniprot id: E4S787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

632335:CALKR RS05600
gene id: 632335:CALKR_RS05600
uniprot id: E4S6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

632335:CALKR RS09850
gene id: 632335:CALKR_RS09850
uniprot id: E4S4T8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

632335:CALKR RS07020
gene id: 632335:CALKR_RS07020
uniprot id: E4S8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

632335:CALKR RS02040
gene id: 632335:CALKR_RS02040
uniprot id: E4S8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS03800
gene id: 632335:CALKR_RS03800
uniprot id: E4S3Y5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

632335:CALKR RS07875
gene id: 632335:CALKR_RS07875
uniprot id: E4S9S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

632335:CALKR RS09110
gene id: 632335:CALKR_RS09110
uniprot id: E4S437
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

632335:CALKR RS01605
gene id: 632335:CALKR_RS01605
uniprot id: E4S840
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

632335:CALKR RS12590
gene id: 632335:CALKR_RS12590
uniprot id: E4S8H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

632335:CALKR RS02425
gene id: 632335:CALKR_RS02425
uniprot id: E4S9I3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

632335:CALKR RS03730
gene id: 632335:CALKR_RS03730
uniprot id: E4S3X1
names: Similarity
messages: Belongs to the UPF0735 family.

632335:CALKR RS01955
gene id: 632335:CALKR_RS01955
uniprot id: E4S8N5
names: Similarity
messages: Belongs to the Fur family.

632335:CALKR RS04485
gene id: 632335:CALKR_RS04485
uniprot id: E4S4Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

632335:CALKR RS01280
gene id: 632335:CALKR_RS01280
uniprot id: E4S7H9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632335:CALKR RS01205
gene id: 632335:CALKR_RS01205
uniprot id: E4S7G6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS09120
gene id: 632335:CALKR_RS09120
uniprot id: E4S439
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

632335:CALKR RS03870
gene id: 632335:CALKR_RS03870
uniprot id: E4S3Z7
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

632335:CALKR RS03830
gene id: 632335:CALKR_RS03830
uniprot id: E4S3Z1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

632335:CALKR RS03760
gene id: 632335:CALKR_RS03760
uniprot id: E4S3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS11010
gene id: 632335:CALKR_RS11010
uniprot id: E4S6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

632335:CALKR RS07870
gene id: 632335:CALKR_RS07870
uniprot id: E4S9S7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS06020
gene id: 632335:CALKR_RS06020
uniprot id: E4S755
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS01925
gene id: 632335:CALKR_RS01925
uniprot id: E4S8N0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632335:CALKR RS02635
gene id: 632335:CALKR_RS02635
uniprot id: E4S9M5
names: Similarity
messages: Belongs to the glutamate synthase family.

632335:CALKR RS10015
gene id: 632335:CALKR_RS10015
uniprot id: E4S4W9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

632335:CALKR RS04175
gene id: 632335:CALKR_RS04175
uniprot id: E4S4C1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

632335:CALKR RS10525
gene id: 632335:CALKR_RS10525
uniprot id: E4S5Q8
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS07045
gene id: 632335:CALKR_RS07045
uniprot id: E4S8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS12630
gene id: 632335:CALKR_RS12630
uniprot id: E4S8I4
names: Similarity
messages: Belongs to the UPF0175 family.

632335:CALKR RS05705
gene id: 632335:CALKR_RS05705
uniprot id: E4S6P1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

632335:CALKR RS06670
gene id: 632335:CALKR_RS06670
uniprot id: E4S875
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

632335:CALKR RS11755
gene id: 632335:CALKR_RS11755
uniprot id: E4S7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS05235
gene id: 632335:CALKR_RS05235
uniprot id: E4S5N6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS12050
gene id: 632335:CALKR_RS12050
uniprot id: E4S7V7
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

632335:CALKR RS11835
gene id: 632335:CALKR_RS11835
uniprot id: E4S7D2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

632335:CALKR RS08220
gene id: 632335:CALKR_RS08220
uniprot id: E4SA54
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

632335:CALKR RS04810
gene id: 632335:CALKR_RS04810
uniprot id: E4S527
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632335:CALKR RS11820
gene id: 632335:CALKR_RS11820
uniprot id: E4S7C9
names: Similarity
messages: Belongs to the peptidase S41A family.

632335:CALKR RS07760
gene id: 632335:CALKR_RS07760
uniprot id: E4S9Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

632335:CALKR RS05465
gene id: 632335:CALKR_RS05465
uniprot id: E4S663
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

632335:CALKR RS06315
gene id: 632335:CALKR_RS06315
uniprot id: E4S7N7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

632335:CALKR RS09105
gene id: 632335:CALKR_RS09105
uniprot id: E4S436
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

632335:CALKR RS07305
gene id: 632335:CALKR_RS07305
uniprot id: E4S8X4
names: Similarity
messages: Belongs to the UPF0111 family.

632335:CALKR RS07370
gene id: 632335:CALKR_RS07370
uniprot id: E4S9B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

632335:CALKR RS08980
gene id: 632335:CALKR_RS08980
uniprot id: E4SAV8
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

632335:CALKR RS06185
gene id: 632335:CALKR_RS06185
uniprot id: E4S788
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

632335:CALKR RS05205
gene id: 632335:CALKR_RS05205
uniprot id: E4S5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

632335:CALKR RS06140
gene id: 632335:CALKR_RS06140
uniprot id: E4S779
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

632335:CALKR RS05175
gene id: 632335:CALKR_RS05175
uniprot id: E4S5M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

632335:CALKR RS00675
gene id: 632335:CALKR_RS00675
uniprot id: E4S632
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

632335:CALKR RS10100
gene id: 632335:CALKR_RS10100
uniprot id: E4S4Y7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS00240
gene id: 632335:CALKR_RS00240
uniprot id: E4S5G8
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS05525
gene id: 632335:CALKR_RS05525
uniprot id: E4S675
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

632335:CALKR RS08180
gene id: 632335:CALKR_RS08180
uniprot id: E4SA45
names: Similarity
messages: Belongs to the thioredoxin family.

632335:CALKR RS08870
gene id: 632335:CALKR_RS08870
uniprot id: E4SAT7
names: Subcellular Location Annotation
messages: Cell membrane

632335:CALKR RS02845
gene id: 632335:CALKR_RS02845
uniprot id: E4S9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS05665
gene id: 632335:CALKR_RS05665
uniprot id: E4S6N3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

632335:CALKR RS01080
gene id: 632335:CALKR_RS01080
uniprot id: E4S708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS00845
gene id: 632335:CALKR_RS00845
uniprot id: E4S6I0
names: Similarity
messages: Belongs to the RutC family.

632335:CALKR RS10290
gene id: 632335:CALKR_RS10290
uniprot id: E4S590
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

632335:CALKR RS04955
gene id: 632335:CALKR_RS04955
uniprot id: E4S556
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632335:CALKR RS04925
gene id: 632335:CALKR_RS04925
uniprot id: E4S550
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

632335:CALKR RS05210
gene id: 632335:CALKR_RS05210
uniprot id: E4S5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

632335:CALKR RS06025
gene id: 632335:CALKR_RS06025
uniprot id: E4S756
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

632335:CALKR RS07835
gene id: 632335:CALKR_RS07835
uniprot id: E4S9S0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

632335:CALKR RS08565
gene id: 632335:CALKR_RS08565
uniprot id: E4SAH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632335:CALKR RS09670
gene id: 632335:CALKR_RS09670
uniprot id: E4S4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

632335:CALKR RS07905
gene id: 632335:CALKR_RS07905
uniprot id: E4S9T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632335:CALKR RS11195
gene id: 632335:CALKR_RS11195
uniprot id: E4S6D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

632335:CALKR RS03970
gene id: 632335:CALKR_RS03970
uniprot id: E4S418
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

632335:CALKR RS04840
gene id: 632335:CALKR_RS04840
uniprot id: E4S533
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

632335:CALKR RS12685
gene id: 632335:CALKR_RS12685
uniprot id: E4S8J2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

632335:CALKR RS11155
gene id: 632335:CALKR_RS11155
uniprot id: E4S6D1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

632335:CALKR RS09445
gene id: 632335:CALKR_RS09445
uniprot id: E4S4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS03965
gene id: 632335:CALKR_RS03965
uniprot id: E4S416
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

632335:CALKR RS07120
gene id: 632335:CALKR_RS07120
uniprot id: E4S8T8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

632335:CALKR RS06820
gene id: 632335:CALKR_RS06820
uniprot id: E4S8A2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

632335:CALKR RS08555
gene id: 632335:CALKR_RS08555
uniprot id: E4SAH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

632335:CALKR RS04690
gene id: 632335:CALKR_RS04690
uniprot id: E4S503
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

632335:CALKR RS07375
gene id: 632335:CALKR_RS07375
uniprot id: E4S9B6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632335:CALKR RS09895
gene id: 632335:CALKR_RS09895
uniprot id: E4S4U6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

632335:CALKR RS07880
gene id: 632335:CALKR_RS07880
uniprot id: E4S9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

632335:CALKR RS12585
gene id: 632335:CALKR_RS12585
uniprot id: E4S8H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

632335:CALKR RS06920
gene id: 632335:CALKR_RS06920
uniprot id: E4S8C2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

632335:CALKR RS09855
gene id: 632335:CALKR_RS09855
uniprot id: E4S4T9
names: Subcellular Location Annotation
messages: Cytoplasm

632335:CALKR RS07845
gene id: 632335:CALKR_RS07845
uniprot id: E4S9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

632335:CALKR RS10030
gene id: 632335:CALKR_RS10030
uniprot id: E4S4X2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS04695
gene id: 632335:CALKR_RS04695
uniprot id: E4S504
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS10090
gene id: 632335:CALKR_RS10090
uniprot id: E4S4Y5
names: Similarity
messages: Belongs to the UPF0175 family.

632335:CALKR RS04305
gene id: 632335:CALKR_RS04305
uniprot id: E4S4E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

632335:CALKR RS02960
gene id: 632335:CALKR_RS02960
uniprot id: E4S9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

632335:CALKR RS03085
gene id: 632335:CALKR_RS03085
uniprot id: E4SA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632335:CALKR RS09770
gene id: 632335:CALKR_RS09770
uniprot id: E4S4M6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

632335:CALKR RS08835
gene id: 632335:CALKR_RS08835
uniprot id: E4SAS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

632335:CALKR RS11185
gene id: 632335:CALKR_RS11185
uniprot id: E4S6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS12855
gene id: 632335:CALKR_RS12855
uniprot id: E4S902
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

632335:CALKR RS00230
gene id: 632335:CALKR_RS00230
uniprot id: E4S5G6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS07730
gene id: 632335:CALKR_RS07730
uniprot id: E4S9Q2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

632335:CALKR RS01575
gene id: 632335:CALKR_RS01575
uniprot id: E4S834
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

632335:CALKR RS06835
gene id: 632335:CALKR_RS06835
uniprot id: E4S8A5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS04060
gene id: 632335:CALKR_RS04060
uniprot id: E4S498
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS07425
gene id: 632335:CALKR_RS07425
uniprot id: E4S9C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

632335:CALKR RS05980
gene id: 632335:CALKR_RS05980
uniprot id: E4S747
names: Similarity
messages: Belongs to the asp23 family.

632335:CALKR RS06165
gene id: 632335:CALKR_RS06165
uniprot id: E4S784
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

632335:CALKR RS09520
gene id: 632335:CALKR_RS09520
uniprot id: E4S4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

632335:CALKR RS01150
gene id: 632335:CALKR_RS01150
uniprot id: E4S724
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS11415
gene id: 632335:CALKR_RS11415
uniprot id: E4S6V4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

632335:CALKR RS10145
gene id: 632335:CALKR_RS10145
uniprot id: E4S562
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS02925
gene id: 632335:CALKR_RS02925
uniprot id: E4S9Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS05135
gene id: 632335:CALKR_RS05135
uniprot id: E4S5L6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

632335:CALKR RS07330
gene id: 632335:CALKR_RS07330
uniprot id: E4S9A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

632335:CALKR RS05925
gene id: 632335:CALKR_RS05925
uniprot id: E4S736
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

632335:CALKR RS11605
gene id: 632335:CALKR_RS11605
uniprot id: E4S6Z1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS04390
gene id: 632335:CALKR_RS04390
uniprot id: E4S4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

632335:CALKR RS09775
gene id: 632335:CALKR_RS09775
uniprot id: E4S4M7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

632335:CALKR RS12770
gene id: 632335:CALKR_RS12770
uniprot id: E4S8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

632335:CALKR RS09780
gene id: 632335:CALKR_RS09780
uniprot id: E4S4T1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

632335:CALKR RS11525
gene id: 632335:CALKR_RS11525
uniprot id: E4S6X5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

632335:CALKR RS11515
gene id: 632335:CALKR_RS11515
uniprot id: E4S6X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

632335:CALKR RS08535
gene id: 632335:CALKR_RS08535
uniprot id: E4SAH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS01055
gene id: 632335:CALKR_RS01055
uniprot id: E4S703
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

632335:CALKR RS06470
gene id: 632335:CALKR_RS06470
uniprot id: E4S7R7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

632335:CALKR RS09045
gene id: 632335:CALKR_RS09045
uniprot id: E4SAX0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

632335:CALKR RS10000
gene id: 632335:CALKR_RS10000
uniprot id: E4S4W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

632335:CALKR RS04285
gene id: 632335:CALKR_RS04285
uniprot id: E4S4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

632335:CALKR RS11300
gene id: 632335:CALKR_RS11300
uniprot id: E4S6T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632335:CALKR RS09645
gene id: 632335:CALKR_RS09645
uniprot id: E4S4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

632335:CALKR RS04075
gene id: 632335:CALKR_RS04075
uniprot id: E4S4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS05350
gene id: 632335:CALKR_RS05350
uniprot id: E4S640
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

632335:CALKR RS10210
gene id: 632335:CALKR_RS10210
uniprot id: E4S575
names: Similarity
messages: Belongs to the UPF0758 family.

632335:CALKR RS06060
gene id: 632335:CALKR_RS06060
uniprot id: E4S763
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

632335:CALKR RS02065
gene id: 632335:CALKR_RS02065
uniprot id: E4S8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

632335:CALKR RS05485
gene id: 632335:CALKR_RS05485
uniprot id: E4S667
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

632335:CALKR RS05690
gene id: 632335:CALKR_RS05690
uniprot id: E4S6N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

632335:CALKR RS03450
gene id: 632335:CALKR_RS03450
uniprot id: E4S600
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

632335:CALKR RS12835
gene id: 632335:CALKR_RS12835
uniprot id: E4S8Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

632335:CALKR RS06625
gene id: 632335:CALKR_RS06625
uniprot id: E4S865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

632335:CALKR RS11165
gene id: 632335:CALKR_RS11165
uniprot id: E4S6D3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

632335:CALKR RS10180
gene id: 632335:CALKR_RS10180
uniprot id: E4S569
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

632335:CALKR RS07390
gene id: 632335:CALKR_RS07390
uniprot id: E4S9B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

632335:CALKR RS08500
gene id: 632335:CALKR_RS08500
uniprot id: E4SAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

632335:CALKR RS08725
gene id: 632335:CALKR_RS08725
uniprot id: E4SAQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

632335:CALKR RS02940
gene id: 632335:CALKR_RS02940
uniprot id: E4S9Z5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

632335:CALKR RS01065
gene id: 632335:CALKR_RS01065
uniprot id: E4S705
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS02895
gene id: 632335:CALKR_RS02895
uniprot id: E4S9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

632335:CALKR RS02055
gene id: 632335:CALKR_RS02055
uniprot id: E4S8Q5
names: Similarity
messages: Belongs to the FlgD family.

632335:CALKR RS09250
gene id: 632335:CALKR_RS09250
uniprot id: E4S463
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

632335:CALKR RS07105
gene id: 632335:CALKR_RS07105
uniprot id: E4S8T5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

632335:CALKR RS07255
gene id: 632335:CALKR_RS07255
uniprot id: E4S8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

632335:CALKR RS11535
gene id: 632335:CALKR_RS11535
uniprot id: E4S6X6
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS05645
gene id: 632335:CALKR_RS05645
uniprot id: E4S6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

632335:CALKR RS05855
gene id: 632335:CALKR_RS05855
uniprot id: E4S6S1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

632335:CALKR RS06785
gene id: 632335:CALKR_RS06785
uniprot id: E4S895
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

632335:CALKR RS04750
gene id: 632335:CALKR_RS04750
uniprot id: E4S515
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

632335:CALKR RS03920
gene id: 632335:CALKR_RS03920
uniprot id: E4S407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS04830
gene id: 632335:CALKR_RS04830
uniprot id: E4S531
names: Similarity
messages: Belongs to the CinA family.

632335:CALKR RS04900
gene id: 632335:CALKR_RS04900
uniprot id: E4S545
names: Similarity
messages: Belongs to the asp23 family.

632335:CALKR RS08470
gene id: 632335:CALKR_RS08470
uniprot id: E4SAG2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

632335:CALKR RS11845
gene id: 632335:CALKR_RS11845
uniprot id: E4S7D4
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS07705
gene id: 632335:CALKR_RS07705
uniprot id: E4S9P7
names: Similarity
messages: Belongs to the UPF0047 family.

632335:CALKR RS04055
gene id: 632335:CALKR_RS04055
uniprot id: E4S497
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

632335:CALKR RS10230
gene id: 632335:CALKR_RS10230
uniprot id: E4S579
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

632335:CALKR RS09975
gene id: 632335:CALKR_RS09975
uniprot id: E4S4W0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

632335:CALKR RS03160
gene id: 632335:CALKR_RS03160
uniprot id: E4SA99
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632335:CALKR RS00485
gene id: 632335:CALKR_RS00485
uniprot id: E4S600
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

632335:CALKR RS01370
gene id: 632335:CALKR_RS01370
uniprot id: E4S7J7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

632335:CALKR RS08795
gene id: 632335:CALKR_RS08795
uniprot id: E4SAS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

632335:CALKR RS10300
gene id: 632335:CALKR_RS10300
uniprot id: E4S591
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

632335:CALKR RS10990
gene id: 632335:CALKR_RS10990
uniprot id: E4S699
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

632335:CALKR RS05545
gene id: 632335:CALKR_RS05545
uniprot id: E4S680
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

632335:CALKR RS03750
gene id: 632335:CALKR_RS03750
uniprot id: E4S3X5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

632335:CALKR RS09505
gene id: 632335:CALKR_RS09505
uniprot id: E4S4H4
names: Similarity
messages: Belongs to the IMPACT family.

632335:CALKR RS08250
gene id: 632335:CALKR_RS08250
uniprot id: E4SA58
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

632335:CALKR RS08875
gene id: 632335:CALKR_RS08875
uniprot id: E4SAT8
names: Similarity
messages: Belongs to the peptidase M18 family.

632335:CALKR RS03630
gene id: 632335:CALKR_RS03630
uniprot id: E4SAP5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

632335:CALKR RS04835
gene id: 632335:CALKR_RS04835
uniprot id: E4S532
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

632335:CALKR RS02035
gene id: 632335:CALKR_RS02035
uniprot id: E4S8Q1
names: Subcellular Location Annotation
messages: Cytoplasm

632335:CALKR RS07280
gene id: 632335:CALKR_RS07280
uniprot id: E4S8W9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

632335:CALKR RS07430
gene id: 632335:CALKR_RS07430
uniprot id: E4S9C7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

632335:CALKR RS01435
gene id: 632335:CALKR_RS01435
uniprot id: E4S7L0
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS12545
gene id: 632335:CALKR_RS12545
uniprot id: E4S8H0
names: Subcellular Location Annotation
messages: Nucleus

632335:CALKR RS11290
gene id: 632335:CALKR_RS11290
uniprot id: E4S6T2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

632335:CALKR RS04520
gene id: 632335:CALKR_RS04520
uniprot id: E4S4Q8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632335:CALKR RS01870
gene id: 632335:CALKR_RS01870
uniprot id: E4S8M2
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

632335:CALKR RS06255
gene id: 632335:CALKR_RS06255
uniprot id: E4S7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

632335:CALKR RS05910
gene id: 632335:CALKR_RS05910
uniprot id: E4S733
names: Similarity
messages: Belongs to the UPF0297 family.

632335:CALKR RS07165
gene id: 632335:CALKR_RS07165
uniprot id: E4S8U7
names: Similarity
messages: Belongs to the HypE family.

632335:CALKR RS07770
gene id: 632335:CALKR_RS07770
uniprot id: E4S9R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

632335:CALKR RS04405
gene id: 632335:CALKR_RS04405
uniprot id: E4S4N5
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

632335:CALKR RS11095
gene id: 632335:CALKR_RS11095
uniprot id: E4S6B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

632335:CALKR RS07395
gene id: 632335:CALKR_RS07395
uniprot id: E4S9C0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

632335:CALKR RS11670
gene id: 632335:CALKR_RS11670
uniprot id: E4S7A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

632335:CALKR RS11145
gene id: 632335:CALKR_RS11145
uniprot id: E4S6C9
names: Similarity
messages: Belongs to the sigma-70 factor family.

632335:CALKR RS04770
gene id: 632335:CALKR_RS04770
uniprot id: E4S519
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

632335:CALKR RS07270
gene id: 632335:CALKR_RS07270
uniprot id: E4S8W7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

632335:CALKR RS00580
gene id: 632335:CALKR_RS00580
uniprot id: E4S620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS08770
gene id: 632335:CALKR_RS08770
uniprot id: E4SAR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

632335:CALKR RS00175
gene id: 632335:CALKR_RS00175
uniprot id: E4S5F9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

632335:CALKR RS07405
gene id: 632335:CALKR_RS07405
uniprot id: E4S9C2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632335:CALKR RS12345
gene id: 632335:CALKR_RS12345
uniprot id: E4S813
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

632335:CALKR RS00535
gene id: 632335:CALKR_RS00535
uniprot id: E4S611
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS06930
gene id: 632335:CALKR_RS06930
uniprot id: E4S8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS06125
gene id: 632335:CALKR_RS06125
uniprot id: E4S776
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

632335:CALKR RS05880
gene id: 632335:CALKR_RS05880
uniprot id: E4S6S6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS05340
gene id: 632335:CALKR_RS05340
uniprot id: E4S638
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

632335:CALKR RS00350
gene id: 632335:CALKR_RS00350
uniprot id: E4S5I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

632335:CALKR RS06405
gene id: 632335:CALKR_RS06405
uniprot id: E4S7Q4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

632335:CALKR RS07345
gene id: 632335:CALKR_RS07345
uniprot id: E4S9B0
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

632335:CALKR RS11750
gene id: 632335:CALKR_RS11750
uniprot id: E4S7B5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS04360
gene id: 632335:CALKR_RS04360
uniprot id: E4S4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

632335:CALKR RS08745
gene id: 632335:CALKR_RS08745
uniprot id: E4SAR1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

632335:CALKR RS01375
gene id: 632335:CALKR_RS01375
uniprot id: E4S7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

632335:CALKR RS09710
gene id: 632335:CALKR_RS09710
uniprot id: E4S4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

632335:CALKR RS05730
gene id: 632335:CALKR_RS05730
uniprot id: E4S6P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

632335:CALKR RS09430
gene id: 632335:CALKR_RS09430
uniprot id: E4S495
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

632335:CALKR RS08780
gene id: 632335:CALKR_RS08780
uniprot id: E4SAR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

632335:CALKR RS05455
gene id: 632335:CALKR_RS05455
uniprot id: E4S661
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

632335:CALKR RS01765
gene id: 632335:CALKR_RS01765
uniprot id: E4S8K5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

632335:CALKR RS05500
gene id: 632335:CALKR_RS05500
uniprot id: E4S670
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

632335:CALKR RS06790
gene id: 632335:CALKR_RS06790
uniprot id: E4S896
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

632335:CALKR RS12675
gene id: 632335:CALKR_RS12675
uniprot id: E4S8J0
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

632335:CALKR RS05865
gene id: 632335:CALKR_RS05865
uniprot id: E4S6S3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

632335:CALKR RS00725
gene id: 632335:CALKR_RS00725
uniprot id: E4S6F6
names: Similarity
messages: Belongs to the Fur family.

632335:CALKR RS06865
gene id: 632335:CALKR_RS06865
uniprot id: E4S8B1
names: Similarity
messages: Belongs to the leucine-binding protein family.

632335:CALKR RS12420
gene id: 632335:CALKR_RS12420
uniprot id: E4S8E7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632335:CALKR RS08370
gene id: 632335:CALKR_RS08370
uniprot id: E4SAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

632335:CALKR RS00975
gene id: 632335:CALKR_RS00975
uniprot id: E4S6K7
names: Similarity
messages: Belongs to the PspA/IM30 family.

632335:CALKR RS10225
gene id: 632335:CALKR_RS10225
uniprot id: E4S578
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

632335:CALKR RS02500
gene id: 632335:CALKR_RS02500
uniprot id: E4S9J7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS08820
gene id: 632335:CALKR_RS08820
uniprot id: E4SAS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

632335:CALKR RS12170
gene id: 632335:CALKR_RS12170
uniprot id: E4S7Y0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

632335:CALKR RS09345
gene id: 632335:CALKR_RS09345
uniprot id: E4S478
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

632335:CALKR RS12830
gene id: 632335:CALKR_RS12830
uniprot id: E4S8Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

632335:CALKR RS13240
gene id: 632335:CALKR_RS13240
uniprot id: E4S712
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

632335:CALKR RS07360
gene id: 632335:CALKR_RS07360
uniprot id: E4S9B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

632335:CALKR RS06080
gene id: 632335:CALKR_RS06080
uniprot id: E4S767
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS02955
gene id: 632335:CALKR_RS02955
uniprot id: E4S9Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

632335:CALKR RS02205
gene id: 632335:CALKR_RS02205
uniprot id: E4S970
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

632335:CALKR RS09000
gene id: 632335:CALKR_RS09000
uniprot id: E4SAW2
names: Similarity
messages: Belongs to the P(II) protein family.

632335:CALKR RS12185
gene id: 632335:CALKR_RS12185
uniprot id: E4S7Y3
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

632335:CALKR RS06720
gene id: 632335:CALKR_RS06720
uniprot id: E4S883
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

632335:CALKR RS01240
gene id: 632335:CALKR_RS01240
uniprot id: E4S7H3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS04450
gene id: 632335:CALKR_RS04450
uniprot id: E4S4P4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

632335:CALKR RS03975
gene id: 632335:CALKR_RS03975
uniprot id: E4S419
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

632335:CALKR RS10190
gene id: 632335:CALKR_RS10190
uniprot id: E4S571
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

632335:CALKR RS00790
gene id: 632335:CALKR_RS00790
uniprot id: E4S6G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS05830
gene id: 632335:CALKR_RS05830
uniprot id: E4S6R6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

632335:CALKR RS08645
gene id: 632335:CALKR_RS08645
uniprot id: E4SAI9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

632335:CALKR RS00295
gene id: 632335:CALKR_RS00295
uniprot id: E4S5H8
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS09020
gene id: 632335:CALKR_RS09020
uniprot id: E4SAW5
names: Similarity
messages: Belongs to the P(II) protein family.

632335:CALKR RS08865
gene id: 632335:CALKR_RS08865
uniprot id: E4SAT6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632335:CALKR RS07160
gene id: 632335:CALKR_RS07160
uniprot id: E4S8U6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS01630
gene id: 632335:CALKR_RS01630
uniprot id: E4S845
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS08900
gene id: 632335:CALKR_RS08900
uniprot id: E4SAU3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

632335:CALKR RS08640
gene id: 632335:CALKR_RS08640
uniprot id: E4SAI8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

632335:CALKR RS01715
gene id: 632335:CALKR_RS01715
uniprot id: E4S857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS06935
gene id: 632335:CALKR_RS06935
uniprot id: E4S8C5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

632335:CALKR RS03610
gene id: 632335:CALKR_RS03610
uniprot id: E4SAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

632335:CALKR RS05965
gene id: 632335:CALKR_RS05965
uniprot id: E4S744
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS07140
gene id: 632335:CALKR_RS07140
uniprot id: E4S8U2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

632335:CALKR RS05550
gene id: 632335:CALKR_RS05550
uniprot id: E4S681
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

632335:CALKR RS04235
gene id: 632335:CALKR_RS04235
uniprot id: E4S4D3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS05115
gene id: 632335:CALKR_RS05115
uniprot id: E4S5L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

632335:CALKR RS11055
gene id: 632335:CALKR_RS11055
uniprot id: E4S6B2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

632335:CALKR RS07470
gene id: 632335:CALKR_RS07470
uniprot id: E4S9D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

632335:CALKR RS05155
gene id: 632335:CALKR_RS05155
uniprot id: E4S5M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

632335:CALKR RS08420
gene id: 632335:CALKR_RS08420
uniprot id: E4SAF2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632335:CALKR RS07100
gene id: 632335:CALKR_RS07100
uniprot id: E4S8T4
names: Similarity
messages: Belongs to the GARS family.

632335:CALKR RS07000
gene id: 632335:CALKR_RS07000
uniprot id: E4S8R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

632335:CALKR RS09385
gene id: 632335:CALKR_RS09385
uniprot id: E4S486
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

632335:CALKR RS00245
gene id: 632335:CALKR_RS00245
uniprot id: E4S5G9
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS12110
gene id: 632335:CALKR_RS12110
uniprot id: E4S7W8
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS09745
gene id: 632335:CALKR_RS09745
uniprot id: E4S4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

632335:CALKR RS02310
gene id: 632335:CALKR_RS02310
uniprot id: E4S991
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS04965
gene id: 632335:CALKR_RS04965
uniprot id: E4S558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS09730
gene id: 632335:CALKR_RS09730
uniprot id: E4S4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

632335:CALKR RS05095
gene id: 632335:CALKR_RS05095
uniprot id: E4S5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

632335:CALKR RS09360
gene id: 632335:CALKR_RS09360
uniprot id: E4S481
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632335:CALKR RS04920
gene id: 632335:CALKR_RS04920
uniprot id: E4S549
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

632335:CALKR RS02645
gene id: 632335:CALKR_RS02645
uniprot id: E4S9M6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632335:CALKR RS09420
gene id: 632335:CALKR_RS09420
uniprot id: E4S493
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

632335:CALKR RS06055
gene id: 632335:CALKR_RS06055
uniprot id: E4S762
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

632335:CALKR RS07225
gene id: 632335:CALKR_RS07225
uniprot id: E4S8V8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

632335:CALKR RS06530
gene id: 632335:CALKR_RS06530
uniprot id: E4S7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

632335:CALKR RS09870
gene id: 632335:CALKR_RS09870
uniprot id: E4S4U2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

632335:CALKR RS01405
gene id: 632335:CALKR_RS01405
uniprot id: E4S7K4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS07245
gene id: 632335:CALKR_RS07245
uniprot id: E4S8W2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

632335:CALKR RS09235
gene id: 632335:CALKR_RS09235
uniprot id: E4S461
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

632335:CALKR RS00835
gene id: 632335:CALKR_RS00835
uniprot id: E4S6H8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632335:CALKR RS06805
gene id: 632335:CALKR_RS06805
uniprot id: E4S899
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS08855
gene id: 632335:CALKR_RS08855
uniprot id: E4SAT4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS01610
gene id: 632335:CALKR_RS01610
uniprot id: E4S841
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS09905
gene id: 632335:CALKR_RS09905
uniprot id: E4S4U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

632335:CALKR RS03715
gene id: 632335:CALKR_RS03715
uniprot id: E4S3W8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

632335:CALKR RS11350
gene id: 632335:CALKR_RS11350
uniprot id: E4S6U4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

632335:CALKR RS08705
gene id: 632335:CALKR_RS08705
uniprot id: E4SAJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

632335:CALKR RS11485
gene id: 632335:CALKR_RS11485
uniprot id: E4S6W8
names: Similarity
messages: Belongs to the UPF0251 family.

632335:CALKR RS03170
gene id: 632335:CALKR_RS03170
uniprot id: E4S600
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

632335:CALKR RS08465
gene id: 632335:CALKR_RS08465
uniprot id: E4SAG1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

632335:CALKR RS07820
gene id: 632335:CALKR_RS07820
uniprot id: E4S9R8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

632335:CALKR RS10550
gene id: 632335:CALKR_RS10550
uniprot id: E4S5R3
names: Similarity
messages: Belongs to the peptidase A24 family.

632335:CALKR RS03195
gene id: 632335:CALKR_RS03195
uniprot id: E4SAA3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS09375
gene id: 632335:CALKR_RS09375
uniprot id: E4S484
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

632335:CALKR RS01130
gene id: 632335:CALKR_RS01130
uniprot id: E4S720
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632335:CALKR RS09615
gene id: 632335:CALKR_RS09615
uniprot id: E4S4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS09660
gene id: 632335:CALKR_RS09660
uniprot id: E4S4K4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632335:CALKR RS06600
gene id: 632335:CALKR_RS06600
uniprot id: E4S860
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

632335:CALKR RS01550
gene id: 632335:CALKR_RS01550
uniprot id: E4S829
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

632335:CALKR RS07895
gene id: 632335:CALKR_RS07895
uniprot id: E4S9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

632335:CALKR RS08290
gene id: 632335:CALKR_RS08290
uniprot id: E4SA66
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

632335:CALKR RS12535
gene id: 632335:CALKR_RS12535
uniprot id: E4S8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

632335:CALKR RS09075
gene id: 632335:CALKR_RS09075
uniprot id: E4SAX6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

632335:CALKR RS08575
gene id: 632335:CALKR_RS08575
uniprot id: E4SAI1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

632335:CALKR RS07605
gene id: 632335:CALKR_RS07605
uniprot id: E4S9F6
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS00320
gene id: 632335:CALKR_RS00320
uniprot id: E4S5I3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

632335:CALKR RS07940
gene id: 632335:CALKR_RS07940
uniprot id: E4S9U0
names: Similarity
messages: Belongs to the SleB family.

632335:CALKR RS04340
gene id: 632335:CALKR_RS04340
uniprot id: E4S4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

632335:CALKR RS03405
gene id: 632335:CALKR_RS03405
uniprot id: E4SAK9
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

632335:CALKR RS09380
gene id: 632335:CALKR_RS09380
uniprot id: E4S485
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

632335:CALKR RS10135
gene id: 632335:CALKR_RS10135
uniprot id: E4S4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

632335:CALKR RS08445
gene id: 632335:CALKR_RS08445
uniprot id: E4SAF7
names: Similarity
messages: Belongs to the FlgM family.

632335:CALKR RS11520
gene id: 632335:CALKR_RS11520
uniprot id: E4S6X4
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632335:CALKR RS09085
gene id: 632335:CALKR_RS09085
uniprot id: E4SAX8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

632335:CALKR RS04295
gene id: 632335:CALKR_RS04295
uniprot id: E4S4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

632335:CALKR RS08760
gene id: 632335:CALKR_RS08760
uniprot id: E4SAR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

632335:CALKR RS09945
gene id: 632335:CALKR_RS09945
uniprot id: E4S4V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

632335:CALKR RS02855
gene id: 632335:CALKR_RS02855
uniprot id: E4S9X5
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

632335:CALKR RS00615
gene id: 632335:CALKR_RS00615
uniprot id: E4S600
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

632335:CALKR RS06275
gene id: 632335:CALKR_RS06275
uniprot id: E4S7N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

632335:CALKR RS08275
gene id: 632335:CALKR_RS08275
uniprot id: E4SA63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

632335:CALKR RS08800
gene id: 632335:CALKR_RS08800
uniprot id: E4SAS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

632335:CALKR RS01535
gene id: 632335:CALKR_RS01535
uniprot id: E4S826
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632335:CALKR RS02605
gene id: 632335:CALKR_RS02605
uniprot id: E4S9L9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632335:CALKR RS02445
gene id: 632335:CALKR_RS02445
uniprot id: E4S9I6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

632335:CALKR RS03925
gene id: 632335:CALKR_RS03925
uniprot id: E4S408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS05190
gene id: 632335:CALKR_RS05190
uniprot id: E4S5M7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

632335:CALKR RS06875
gene id: 632335:CALKR_RS06875
uniprot id: E4S8B3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632335:CALKR RS02865
gene id: 632335:CALKR_RS02865
uniprot id: E4S9X7
names: Similarity
messages: Belongs to the PGI/PMI family.

632335:CALKR RS09515
gene id: 632335:CALKR_RS09515
uniprot id: E4S4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

632335:CALKR RS08590
gene id: 632335:CALKR_RS08590
uniprot id: E4SAI4
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS06565
gene id: 632335:CALKR_RS06565
uniprot id: E4S7T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS11430
gene id: 632335:CALKR_RS11430
uniprot id: E4S6V7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

632335:CALKR RS08815
gene id: 632335:CALKR_RS08815
uniprot id: E4SAS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

632335:CALKR RS02985
gene id: 632335:CALKR_RS02985
uniprot id: E4SA04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

632335:CALKR RS10220
gene id: 632335:CALKR_RS10220
uniprot id: E4S577
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

632335:CALKR RS04330
gene id: 632335:CALKR_RS04330
uniprot id: E4S4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

632335:CALKR RS06425
gene id: 632335:CALKR_RS06425
uniprot id: E4S7Q8
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

632335:CALKR RS13850
gene id: 632335:CALKR_RS13850
uniprot id: E4S9G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

632335:CALKR RS04040
gene id: 632335:CALKR_RS04040
uniprot id: E4S432
names: Similarity
messages: Belongs to the peptidase C40 family.

632335:CALKR RS01785
gene id: 632335:CALKR_RS01785
uniprot id: E4S8K8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS06205
gene id: 632335:CALKR_RS06205
uniprot id: E4S792
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

632335:CALKR RS10930
gene id: 632335:CALKR_RS10930
uniprot id: E4S687
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632335:CALKR RS12670
gene id: 632335:CALKR_RS12670
uniprot id: E4S8I9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

632335:CALKR RS04210
gene id: 632335:CALKR_RS04210
uniprot id: E4S4C8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

632335:CALKR RS10070
gene id: 632335:CALKR_RS10070
uniprot id: E4S4Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS10195
gene id: 632335:CALKR_RS10195
uniprot id: E4S572
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

632335:CALKR RS03840
gene id: 632335:CALKR_RS03840
uniprot id: E4S3Z3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

632335:CALKR RS07545
gene id: 632335:CALKR_RS07545
uniprot id: E4S9E6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

632335:CALKR RS07525
gene id: 632335:CALKR_RS07525
uniprot id: E4S9E2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632335:CALKR RS05440
gene id: 632335:CALKR_RS05440
uniprot id: E4S658
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632335:CALKR RS05630
gene id: 632335:CALKR_RS05630
uniprot id: E4S6M6
names: Similarity
messages: Belongs to the UPF0473 family.

632335:CALKR RS04675
gene id: 632335:CALKR_RS04675
uniprot id: E4S500
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

632335:CALKR RS03070
gene id: 632335:CALKR_RS03070
uniprot id: E4SA84
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS02980
gene id: 632335:CALKR_RS02980
uniprot id: E4SA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

632335:CALKR RS04200
gene id: 632335:CALKR_RS04200
uniprot id: E4S4C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

632335:CALKR RS05105
gene id: 632335:CALKR_RS05105
uniprot id: E4S5L0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS05505
gene id: 632335:CALKR_RS05505
uniprot id: E4S671
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

632335:CALKR RS08710
gene id: 632335:CALKR_RS08710
uniprot id: E4SAK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

632335:CALKR RS02860
gene id: 632335:CALKR_RS02860
uniprot id: E4S9X6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632335:CALKR RS03050
gene id: 632335:CALKR_RS03050
uniprot id: E4SA81
names: Similarity
messages: Belongs to the threonine synthase family.

632335:CALKR RS06030
gene id: 632335:CALKR_RS06030
uniprot id: E4S757
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

632335:CALKR RS01510
gene id: 632335:CALKR_RS01510
uniprot id: E4S821
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS02300
gene id: 632335:CALKR_RS02300
uniprot id: E4S989
names: Similarity
messages: Belongs to the UPF0237 family.

632335:CALKR RS05480
gene id: 632335:CALKR_RS05480
uniprot id: E4S666
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

632335:CALKR RS03835
gene id: 632335:CALKR_RS03835
uniprot id: E4S3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

632335:CALKR RS02495
gene id: 632335:CALKR_RS02495
uniprot id: E4S9J6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

632335:CALKR RS07350
gene id: 632335:CALKR_RS07350
uniprot id: E4S9B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

632335:CALKR RS07435
gene id: 632335:CALKR_RS07435
uniprot id: E4S9C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

632335:CALKR RS05165
gene id: 632335:CALKR_RS05165
uniprot id: E4S5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

632335:CALKR RS04195
gene id: 632335:CALKR_RS04195
uniprot id: E4S4C5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

632335:CALKR RS07115
gene id: 632335:CALKR_RS07115
uniprot id: E4S8T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

632335:CALKR RS05845
gene id: 632335:CALKR_RS05845
uniprot id: E4S6R9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

632335:CALKR RS11640
gene id: 632335:CALKR_RS11640
uniprot id: E4S798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS00875
gene id: 632335:CALKR_RS00875
uniprot id: E4S6I7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

632335:CALKR RS12410
gene id: 632335:CALKR_RS12410
uniprot id: E4S8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

632335:CALKR RS05695
gene id: 632335:CALKR_RS05695
uniprot id: E4S6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

632335:CALKR RS09535
gene id: 632335:CALKR_RS09535
uniprot id: E4S4I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

632335:CALKR RS05720
gene id: 632335:CALKR_RS05720
uniprot id: E4S6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

632335:CALKR RS04505
gene id: 632335:CALKR_RS04505
uniprot id: E4S4Q5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS02115
gene id: 632335:CALKR_RS02115
uniprot id: E4S953
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

632335:CALKR RS04445
gene id: 632335:CALKR_RS04445
uniprot id: E4S4P3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

632335:CALKR RS11815
gene id: 632335:CALKR_RS11815
uniprot id: E4S7C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS06400
gene id: 632335:CALKR_RS06400
uniprot id: E4S7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

632335:CALKR RS05895
gene id: 632335:CALKR_RS05895
uniprot id: E4S730
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

632335:CALKR RS04350
gene id: 632335:CALKR_RS04350
uniprot id: E4S4F6
names: Similarity
messages: Belongs to the CdaR family.

632335:CALKR RS05975
gene id: 632335:CALKR_RS05975
uniprot id: E4S746
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

632335:CALKR RS07935
gene id: 632335:CALKR_RS07935
uniprot id: E4S9T9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

632335:CALKR RS07775
gene id: 632335:CALKR_RS07775
uniprot id: E4S9R1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

632335:CALKR RS09820
gene id: 632335:CALKR_RS09820
uniprot id: E4S4T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

632335:CALKR RS06900
gene id: 632335:CALKR_RS06900
uniprot id: E4S8B8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

632335:CALKR RS04825
gene id: 632335:CALKR_RS04825
uniprot id: E4S530
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

632335:CALKR RS07420
gene id: 632335:CALKR_RS07420
uniprot id: E4S9C5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632335:CALKR RS05160
gene id: 632335:CALKR_RS05160
uniprot id: E4S5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

632335:CALKR RS05900
gene id: 632335:CALKR_RS05900
uniprot id: E4S731
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

632335:CALKR RS11250
gene id: 632335:CALKR_RS11250
uniprot id: E4S6F0
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS09415
gene id: 632335:CALKR_RS09415
uniprot id: E4S492
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

632335:CALKR RS04070
gene id: 632335:CALKR_RS04070
uniprot id: E4S4A0
names: Similarity
messages: Belongs to the GSP E family.

632335:CALKR RS03720
gene id: 632335:CALKR_RS03720
uniprot id: E4S3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

632335:CALKR RS08150
gene id: 632335:CALKR_RS08150
uniprot id: E4SA39
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

632335:CALKR RS12190
gene id: 632335:CALKR_RS12190
uniprot id: E4S7Y4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS05535
gene id: 632335:CALKR_RS05535
uniprot id: E4S677
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

632335:CALKR RS12035
gene id: 632335:CALKR_RS12035
uniprot id: E4S7V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

632335:CALKR RS12275
gene id: 632335:CALKR_RS12275
uniprot id: E4S801
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

632335:CALKR RS04760
gene id: 632335:CALKR_RS04760
uniprot id: E4S517
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

632335:CALKR RS12555
gene id: 632335:CALKR_RS12555
uniprot id: E4S8H2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

632335:CALKR RS09930
gene id: 632335:CALKR_RS09930
uniprot id: E4S4V1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

632335:CALKR RS06135
gene id: 632335:CALKR_RS06135
uniprot id: E4S778
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

632335:CALKR RS01940
gene id: 632335:CALKR_RS01940
uniprot id: E4S8N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS05295
gene id: 632335:CALKR_RS05295
uniprot id: E4S5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

632335:CALKR RS02090
gene id: 632335:CALKR_RS02090
uniprot id: E4S948
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS11085
gene id: 632335:CALKR_RS11085
uniprot id: E4S6B7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

632335:CALKR RS13100
gene id: 632335:CALKR_RS13100
uniprot id: E4S9G7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

632335:CALKR RS09010
gene id: 632335:CALKR_RS09010
uniprot id: E4SAW4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-98 inactivates the nitrogenase reductase and regulates nitrogenase activity.

632335:CALKR RS12680
gene id: 632335:CALKR_RS12680
uniprot id: E4S8J1
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

632335:CALKR RS02165
gene id: 632335:CALKR_RS02165
uniprot id: E4S963
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

632335:CALKR RS13085
gene id: 632335:CALKR_RS13085
uniprot id: E4S9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

632335:CALKR RS12735
gene id: 632335:CALKR_RS12735
uniprot id: E4S8X7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS11480
gene id: 632335:CALKR_RS11480
uniprot id: E4S6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

632335:CALKR RS09640
gene id: 632335:CALKR_RS09640
uniprot id: E4S4K0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

632335:CALKR RS06550
gene id: 632335:CALKR_RS06550
uniprot id: E4S7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

632335:CALKR RS07530
gene id: 632335:CALKR_RS07530
uniprot id: E4S9E3
names: Similarity
messages: Belongs to the UPF0047 family.

632335:CALKR RS02615
gene id: 632335:CALKR_RS02615
uniprot id: E4S9M1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

632335:CALKR RS07475
gene id: 632335:CALKR_RS07475
uniprot id: E4S9D2
names: Similarity
messages: Belongs to the UPF0342 family.

632335:CALKR RS11405
gene id: 632335:CALKR_RS11405
uniprot id: E4S6V2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

632335:CALKR RS03900
gene id: 632335:CALKR_RS03900
uniprot id: E4S403
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS09700
gene id: 632335:CALKR_RS09700
uniprot id: E4S4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

632335:CALKR RS00765
gene id: 632335:CALKR_RS00765
uniprot id: E4S6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

632335:CALKR RS11205
gene id: 632335:CALKR_RS11205
uniprot id: E4S6E1
names: Similarity
messages: Belongs to the phosphopentomutase family.

632335:CALKR RS08825
gene id: 632335:CALKR_RS08825
uniprot id: E4SAS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

632335:CALKR RS07975
gene id: 632335:CALKR_RS07975
uniprot id: E4S9U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

632335:CALKR RS10130
gene id: 632335:CALKR_RS10130
uniprot id: E4S4Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS04845
gene id: 632335:CALKR_RS04845
uniprot id: E4S534
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

632335:CALKR RS11425
gene id: 632335:CALKR_RS11425
uniprot id: E4S6V6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

632335:CALKR RS09705
gene id: 632335:CALKR_RS09705
uniprot id: E4S4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

632335:CALKR RS07900
gene id: 632335:CALKR_RS07900
uniprot id: E4S9T3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

632335:CALKR RS03260
gene id: 632335:CALKR_RS03260
uniprot id: E4SAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

632335:CALKR RS08415
gene id: 632335:CALKR_RS08415
uniprot id: E4SAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

632335:CALKR RS11465
gene id: 632335:CALKR_RS11465
uniprot id: E4S6W4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632335:CALKR RS06430
gene id: 632335:CALKR_RS06430
uniprot id: E4S7Q9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

632335:CALKR RS12175
gene id: 632335:CALKR_RS12175
uniprot id: E4S7Y1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

632335:CALKR RS01230
gene id: 632335:CALKR_RS01230
uniprot id: E4S7H1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

632335:CALKR RS00815
gene id: 632335:CALKR_RS00815
uniprot id: E4S6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS10460
gene id: 632335:CALKR_RS10460
uniprot id: E4S5C2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

632335:CALKR RS05250
gene id: 632335:CALKR_RS05250
uniprot id: E4S5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS04670
gene id: 632335:CALKR_RS04670
uniprot id: E4S4Z9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

632335:CALKR RS13105
gene id: 632335:CALKR_RS13105
uniprot id: E4S9G8
names: Similarity
messages: Belongs to the GerABKA family.

632335:CALKR RS04930
gene id: 632335:CALKR_RS04930
uniprot id: E4S551
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS02230
gene id: 632335:CALKR_RS02230
uniprot id: E4S975
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS02110
gene id: 632335:CALKR_RS02110
uniprot id: E4S952
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

632335:CALKR RS08520
gene id: 632335:CALKR_RS08520
uniprot id: E4SAH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

632335:CALKR RS09295
gene id: 632335:CALKR_RS09295
uniprot id: E4S468
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

632335:CALKR RS05670
gene id: 632335:CALKR_RS05670
uniprot id: E4S6N4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

632335:CALKR RS12040
gene id: 632335:CALKR_RS12040
uniprot id: E4S7V5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

632335:CALKR RS02340
gene id: 632335:CALKR_RS02340
uniprot id: E4S997
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632335:CALKR RS04745
gene id: 632335:CALKR_RS04745
uniprot id: E4S514
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

632335:CALKR RS02625
gene id: 632335:CALKR_RS02625
uniprot id: E4S9M3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

632335:CALKR RS01540
gene id: 632335:CALKR_RS01540
uniprot id: E4S827
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

632335:CALKR RS06780
gene id: 632335:CALKR_RS06780
uniprot id: E4S894
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

632335:CALKR RS06630
gene id: 632335:CALKR_RS06630
uniprot id: E4S866
names: Similarity
messages: Belongs to the YggT family.

632335:CALKR RS11970
gene id: 632335:CALKR_RS11970
uniprot id: E4S7U2
names: Similarity
messages: Belongs to the glutamate synthase family.

632335:CALKR RS03910
gene id: 632335:CALKR_RS03910
uniprot id: E4S405
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

632335:CALKR RS02520
gene id: 632335:CALKR_RS02520
uniprot id: E4S9K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

632335:CALKR RS12245
gene id: 632335:CALKR_RS12245
uniprot id: E4S7Z5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS09965
gene id: 632335:CALKR_RS09965
uniprot id: E4S4V8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

632335:CALKR RS00445
gene id: 632335:CALKR_RS00445
uniprot id: E4S5Z2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

632335:CALKR RS03745
gene id: 632335:CALKR_RS03745
uniprot id: E4S3X4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

632335:CALKR RS12540
gene id: 632335:CALKR_RS12540
uniprot id: E4S8G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

632335:CALKR RS02745
gene id: 632335:CALKR_RS02745
uniprot id: E4S9V8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS00060
gene id: 632335:CALKR_RS00060
uniprot id: E4S5E2
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS05635
gene id: 632335:CALKR_RS05635
uniprot id: E4S6M7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

632335:CALKR RS07130
gene id: 632335:CALKR_RS07130
uniprot id: E4S8U0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

632335:CALKR RS05270
gene id: 632335:CALKR_RS05270
uniprot id: E4S5P3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

632335:CALKR RS07380
gene id: 632335:CALKR_RS07380
uniprot id: E4S9B7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

632335:CALKR RS11070
gene id: 632335:CALKR_RS11070
uniprot id: E4S6B5
names: Similarity
messages: Belongs to the hemerythrin family.

632335:CALKR RS08995
gene id: 632335:CALKR_RS08995
uniprot id: E4SAW1
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

632335:CALKR RS05260
gene id: 632335:CALKR_RS05260
uniprot id: E4S5P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

632335:CALKR RS02285
gene id: 632335:CALKR_RS02285
uniprot id: E4S986
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

632335:CALKR RS06725
gene id: 632335:CALKR_RS06725
uniprot id: E4S884
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

632335:CALKR RS03770
gene id: 632335:CALKR_RS03770
uniprot id: E4S3X9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS06440
gene id: 632335:CALKR_RS06440
uniprot id: E4S7R1
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS13855
gene id: 632335:CALKR_RS13855
uniprot id: E4S9G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

632335:CALKR RS01060
gene id: 632335:CALKR_RS01060
uniprot id: E4S704
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS01745
gene id: 632335:CALKR_RS01745
uniprot id: E4S8K1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632335:CALKR RS05055
gene id: 632335:CALKR_RS05055
uniprot id: E4S5K1
names: Similarity
messages: Belongs to the peptidase S8 family.

632335:CALKR RS07175
gene id: 632335:CALKR_RS07175
uniprot id: E4S8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

632335:CALKR RS05215
gene id: 632335:CALKR_RS05215
uniprot id: E4S5N2
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

632335:CALKR RS07840
gene id: 632335:CALKR_RS07840
uniprot id: E4S9S1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS12825
gene id: 632335:CALKR_RS12825
uniprot id: E4S8Z6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

632335:CALKR RS09150
gene id: 632335:CALKR_RS09150
uniprot id: E4S444
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS11735
gene id: 632335:CALKR_RS11735
uniprot id: E4S7B2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

632335:CALKR RS09620
gene id: 632335:CALKR_RS09620
uniprot id: E4S4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS07085
gene id: 632335:CALKR_RS07085
uniprot id: E4S8T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

632335:CALKR RS00010
gene id: 632335:CALKR_RS00010
uniprot id: E4S5D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

632335:CALKR RS07040
gene id: 632335:CALKR_RS07040
uniprot id: E4S8S2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

632335:CALKR RS10055
gene id: 632335:CALKR_RS10055
uniprot id: E4S4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS03785
gene id: 632335:CALKR_RS03785
uniprot id: E4S3Y2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

632335:CALKR RS08730
gene id: 632335:CALKR_RS08730
uniprot id: E4SAQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

632335:CALKR RS01865
gene id: 632335:CALKR_RS01865
uniprot id: E4S8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

632335:CALKR RS00195
gene id: 632335:CALKR_RS00195
uniprot id: E4S5G2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

632335:CALKR RS05380
gene id: 632335:CALKR_RS05380
uniprot id: E4S646
names: Similarity
messages: Belongs to the HypD family.

632335:CALKR RS04475
gene id: 632335:CALKR_RS04475
uniprot id: E4S4P9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

632335:CALKR RS05335
gene id: 632335:CALKR_RS05335
uniprot id: E4S5Q6
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS08260
gene id: 632335:CALKR_RS08260
uniprot id: E4SA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS09130
gene id: 632335:CALKR_RS09130
uniprot id: E4S441
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

632335:CALKR RS06995
gene id: 632335:CALKR_RS06995
uniprot id: E4S8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

632335:CALKR RS06385
gene id: 632335:CALKR_RS06385
uniprot id: E4S7Q0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

632335:CALKR RS07415
gene id: 632335:CALKR_RS07415
uniprot id: E4S9C4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

632335:CALKR RS05990
gene id: 632335:CALKR_RS05990
uniprot id: E4S749
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

632335:CALKR RS12690
gene id: 632335:CALKR_RS12690
uniprot id: E4S8J3
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

632335:CALKR RS02455
gene id: 632335:CALKR_RS02455
uniprot id: E4S9I8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

632335:CALKR RS06335
gene id: 632335:CALKR_RS06335
uniprot id: E4S7P0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

632335:CALKR RS11400
gene id: 632335:CALKR_RS11400
uniprot id: E4S6V1
names: Similarity
messages: Belongs to the archaeal-type GPI family.

632335:CALKR RS11950
gene id: 632335:CALKR_RS11950
uniprot id: E4S7F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

632335:CALKR RS05435
gene id: 632335:CALKR_RS05435
uniprot id: E4S657
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

632335:CALKR RS08755
gene id: 632335:CALKR_RS08755
uniprot id: E4SAR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

632335:CALKR RS11635
gene id: 632335:CALKR_RS11635
uniprot id: E4S797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS13170
gene id: 632335:CALKR_RS13170
uniprot id: E4SAY7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

632335:CALKR RS01625
gene id: 632335:CALKR_RS01625
uniprot id: E4S844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

632335:CALKR RS02000
gene id: 632335:CALKR_RS02000
uniprot id: E4S8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

632335:CALKR RS06915
gene id: 632335:CALKR_RS06915
uniprot id: E4S8C1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

632335:CALKR RS09005
gene id: 632335:CALKR_RS09005
uniprot id: E4SAW3
names: Similarity
messages: Belongs to the P(II) protein family.

632335:CALKR RS11395
gene id: 632335:CALKR_RS11395
uniprot id: E4S6V0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

632335:CALKR RS02990
gene id: 632335:CALKR_RS02990
uniprot id: E4SA05
names: Similarity
messages: Belongs to the glutamine synthetase family.

632335:CALKR RS01075
gene id: 632335:CALKR_RS01075
uniprot id: E4S707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS04755
gene id: 632335:CALKR_RS04755
uniprot id: E4S516
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

632335:CALKR RS02875
gene id: 632335:CALKR_RS02875
uniprot id: E4S9X9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

632335:CALKR RS03645
gene id: 632335:CALKR_RS03645
uniprot id: E4SAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

632335:CALKR RS10215
gene id: 632335:CALKR_RS10215
uniprot id: E4S576
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

632335:CALKR RS01350
gene id: 632335:CALKR_RS01350
uniprot id: E4S7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

632335:CALKR RS12255
gene id: 632335:CALKR_RS12255
uniprot id: E4S7Z7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS12290
gene id: 632335:CALKR_RS12290
uniprot id: E4S804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

632335:CALKR RS08530
gene id: 632335:CALKR_RS08530
uniprot id: E4SAH2
names: Similarity
messages: Belongs to the TrpC family.

632335:CALKR RS10080
gene id: 632335:CALKR_RS10080
uniprot id: E4S4Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

632335:CALKR RS04310
gene id: 632335:CALKR_RS04310
uniprot id: E4S4E8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS01830
gene id: 632335:CALKR_RS01830
uniprot id: E4S8L5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

632335:CALKR RS07505
gene id: 632335:CALKR_RS07505
uniprot id: E4S9D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

632335:CALKR RS11885
gene id: 632335:CALKR_RS11885
uniprot id: E4S7E1
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS05715
gene id: 632335:CALKR_RS05715
uniprot id: E4S6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS03255
gene id: 632335:CALKR_RS03255
uniprot id: E4SAB5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS02890
gene id: 632335:CALKR_RS02890
uniprot id: E4S9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

632335:CALKR RS11610
gene id: 632335:CALKR_RS11610
uniprot id: E4S6Z2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS12595
gene id: 632335:CALKR_RS12595
uniprot id: E4S8H9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

632335:CALKR RS00585
gene id: 632335:CALKR_RS00585
uniprot id: E4S621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS06590
gene id: 632335:CALKR_RS06590
uniprot id: E4S7U1
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS06800
gene id: 632335:CALKR_RS06800
uniprot id: E4S898
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

632335:CALKR RS09675
gene id: 632335:CALKR_RS09675
uniprot id: E4S4K7
names: Similarity
messages: Belongs to the UPF0749 family.

632335:CALKR RS01985
gene id: 632335:CALKR_RS01985
uniprot id: E4S8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

632335:CALKR RS06340
gene id: 632335:CALKR_RS06340
uniprot id: E4S7P1
names: Similarity
messages: Belongs to the TlyA family.

632335:CALKR RS11725
gene id: 632335:CALKR_RS11725
uniprot id: E4S7B1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

632335:CALKR RS03235
gene id: 632335:CALKR_RS03235
uniprot id: E4SAB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

632335:CALKR RS03955
gene id: 632335:CALKR_RS03955
uniprot id: E4S414
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS05745
gene id: 632335:CALKR_RS05745
uniprot id: E4S6P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

632335:CALKR RS13010
gene id: 632335:CALKR_RS13010
uniprot id: E4S931
names: Similarity
messages: Belongs to the class-I fumarase family.

632335:CALKR RS06945
gene id: 632335:CALKR_RS06945
uniprot id: E4S8C7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

632335:CALKR RS06370
gene id: 632335:CALKR_RS06370
uniprot id: E4S7P7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

632335:CALKR RS02355
gene id: 632335:CALKR_RS02355
uniprot id: E4S9A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

632335:CALKR RS05460
gene id: 632335:CALKR_RS05460
uniprot id: E4S662
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

632335:CALKR RS01135
gene id: 632335:CALKR_RS01135
uniprot id: E4S721
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

632335:CALKR RS02725
gene id: 632335:CALKR_RS02725
uniprot id: E4S9V4
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS06420
gene id: 632335:CALKR_RS06420
uniprot id: E4S7Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

632335:CALKR RS13110
gene id: 632335:CALKR_RS13110
uniprot id: E4S9G9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

632335:CALKR RS04300
gene id: 632335:CALKR_RS04300
uniprot id: E4S4E6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

632335:CALKR RS06825
gene id: 632335:CALKR_RS06825
uniprot id: E4S8A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

632335:CALKR RS06200
gene id: 632335:CALKR_RS06200
uniprot id: E4S791
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

632335:CALKR RS06555
gene id: 632335:CALKR_RS06555
uniprot id: E4S7T4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

632335:CALKR RS08830
gene id: 632335:CALKR_RS08830
uniprot id: E4SAS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

632335:CALKR RS03200
gene id: 632335:CALKR_RS03200
uniprot id: E4SAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS07265
gene id: 632335:CALKR_RS07265
uniprot id: E4S8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

632335:CALKR RS12775
gene id: 632335:CALKR_RS12775
uniprot id: E4S8Y5
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

632335:CALKR RS01300
gene id: 632335:CALKR_RS01300
uniprot id: E4S7I2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

632335:CALKR RS01700
gene id: 632335:CALKR_RS01700
uniprot id: E4S854
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

632335:CALKR RS03240
gene id: 632335:CALKR_RS03240
uniprot id: E4SAB2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

632335:CALKR RS02485
gene id: 632335:CALKR_RS02485
uniprot id: E4S9J3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

632335:CALKR RS05180
gene id: 632335:CALKR_RS05180
uniprot id: E4S5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

632335:CALKR RS09115
gene id: 632335:CALKR_RS09115
uniprot id: E4S438
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS02120
gene id: 632335:CALKR_RS02120
uniprot id: E4S954
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

632335:CALKR RS07915
gene id: 632335:CALKR_RS07915
uniprot id: E4S9T6
names: Similarity
messages: Belongs to the CapA family.

632335:CALKR RS01390
gene id: 632335:CALKR_RS01390
uniprot id: E4S7K1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

632335:CALKR RS06815
gene id: 632335:CALKR_RS06815
uniprot id: E4S8A1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS05360
gene id: 632335:CALKR_RS05360
uniprot id: E4S642
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

632335:CALKR RS02350
gene id: 632335:CALKR_RS02350
uniprot id: E4S999
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

632335:CALKR RS06905
gene id: 632335:CALKR_RS06905
uniprot id: E4S8B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

632335:CALKR RS07295
gene id: 632335:CALKR_RS07295
uniprot id: E4S8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

632335:CALKR RS01825
gene id: 632335:CALKR_RS01825
uniprot id: E4S8L4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

632335:CALKR RS00305
gene id: 632335:CALKR_RS00305
uniprot id: E4S5I0
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS04255
gene id: 632335:CALKR_RS04255
uniprot id: E4S4D7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS08025
gene id: 632335:CALKR_RS08025
uniprot id: E4SA15
names: Similarity
messages: Belongs to the AAA ATPase family.

632335:CALKR RS09435
gene id: 632335:CALKR_RS09435
uniprot id: E4S4G0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

632335:CALKR RS13075
gene id: 632335:CALKR_RS13075
uniprot id: E4S9G2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS04180
gene id: 632335:CALKR_RS04180
uniprot id: E4S4C2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

632335:CALKR RS06810
gene id: 632335:CALKR_RS06810
uniprot id: E4S8A0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

632335:CALKR RS02305
gene id: 632335:CALKR_RS02305
uniprot id: E4S990
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

632335:CALKR RS07285
gene id: 632335:CALKR_RS07285
uniprot id: E4S8X0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

632335:CALKR RS07250
gene id: 632335:CALKR_RS07250
uniprot id: E4S8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

632335:CALKR RS05870
gene id: 632335:CALKR_RS05870
uniprot id: E4S6S4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

632335:CALKR RS04765
gene id: 632335:CALKR_RS04765
uniprot id: E4S518
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

632335:CALKR RS10970
gene id: 632335:CALKR_RS10970
uniprot id: E4S695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS09915
gene id: 632335:CALKR_RS09915
uniprot id: E4S4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

632335:CALKR RS00870
gene id: 632335:CALKR_RS00870
uniprot id: E4S6I6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

632335:CALKR RS02105
gene id: 632335:CALKR_RS02105
uniprot id: E4S951
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

632335:CALKR RS02005
gene id: 632335:CALKR_RS02005
uniprot id: E4S8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

632335:CALKR RS04815
gene id: 632335:CALKR_RS04815
uniprot id: E4S528
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

632335:CALKR RS02420
gene id: 632335:CALKR_RS02420
uniprot id: E4S9I2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

632335:CALKR RS11125
gene id: 632335:CALKR_RS11125
uniprot id: E4S6C5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

632335:CALKR RS03815
gene id: 632335:CALKR_RS03815
uniprot id: E4S3Y8
names: Similarity
messages: Belongs to the EamA transporter family.

632335:CALKR RS05650
gene id: 632335:CALKR_RS05650
uniprot id: E4S6N0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

632335:CALKR RS13050
gene id: 632335:CALKR_RS13050
uniprot id: E4S939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

632335:CALKR RS06585
gene id: 632335:CALKR_RS06585
uniprot id: E4S7U0
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS05230
gene id: 632335:CALKR_RS05230
uniprot id: E4S5N5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

632335:CALKR RS09665
gene id: 632335:CALKR_RS09665
uniprot id: E4S4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

632335:CALKR RS03805
gene id: 632335:CALKR_RS03805
uniprot id: E4S3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS07780
gene id: 632335:CALKR_RS07780
uniprot id: E4S9R2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

632335:CALKR RS09545
gene id: 632335:CALKR_RS09545
uniprot id: E4S4I2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

632335:CALKR RS13035
gene id: 632335:CALKR_RS13035
uniprot id: E4S936
names: Similarity
messages: Belongs to the ParB family.

632335:CALKR RS07790
gene id: 632335:CALKR_RS07790
uniprot id: E4S9R4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

632335:CALKR RS09720
gene id: 632335:CALKR_RS09720
uniprot id: E4S4L6
names: Similarity
messages: Belongs to the transpeptidase family.

632335:CALKR RS04945
gene id: 632335:CALKR_RS04945
uniprot id: E4S554
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

632335:CALKR RS09080
gene id: 632335:CALKR_RS09080
uniprot id: E4SAX7
names: Similarity
messages: Belongs to the class-I fumarase family.

632335:CALKR RS02410
gene id: 632335:CALKR_RS02410
uniprot id: E4S9I0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS05075
gene id: 632335:CALKR_RS05075
uniprot id: E4S5K4
names: Similarity
messages: Belongs to the histone deacetylase family.

632335:CALKR RS05305
gene id: 632335:CALKR_RS05305
uniprot id: E4S5Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

632335:CALKR RS02560
gene id: 632335:CALKR_RS02560
uniprot id: E4S9L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

632335:CALKR RS07030
gene id: 632335:CALKR_RS07030
uniprot id: E4S8S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

632335:CALKR RS05315
gene id: 632335:CALKR_RS05315
uniprot id: E4S5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

632335:CALKR RS02880
gene id: 632335:CALKR_RS02880
uniprot id: E4S9Y2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

632335:CALKR RS01640
gene id: 632335:CALKR_RS01640
uniprot id: E4S847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

632335:CALKR RS07535
gene id: 632335:CALKR_RS07535
uniprot id: E4S9E4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632335:CALKR RS03000
gene id: 632335:CALKR_RS03000
uniprot id: E4SA07
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

632335:CALKR RS02750
gene id: 632335:CALKR_RS02750
uniprot id: E4S9V9
names: Similarity
messages: Belongs to the UPF0145 family.

632335:CALKR RS08195
gene id: 632335:CALKR_RS08195
uniprot id: E4SA48
names: Similarity
messages: Belongs to the EamA transporter family.

632335:CALKR RS02085
gene id: 632335:CALKR_RS02085
uniprot id: E4S947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

632335:CALKR RS07490
gene id: 632335:CALKR_RS07490
uniprot id: E4S9D5
names: Similarity
messages: Belongs to the RecJ family.

632335:CALKR RS04430
gene id: 632335:CALKR_RS04430
uniprot id: E4S4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

632335:CALKR RS03150
gene id: 632335:CALKR_RS03150
uniprot id: E4SA97
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

632335:CALKR RS03985
gene id: 632335:CALKR_RS03985
uniprot id: E4S421
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

632335:CALKR RS02025
gene id: 632335:CALKR_RS02025
uniprot id: E4S8P9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

632335:CALKR RS04820
gene id: 632335:CALKR_RS04820
uniprot id: E4S529
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

632335:CALKR RS00395
gene id: 632335:CALKR_RS00395
uniprot id: E4S5Y1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632335:CALKR RS03740
gene id: 632335:CALKR_RS03740
uniprot id: E4S3X3
names: Similarity
messages: Belongs to the GerABKA family.

632335:CALKR RS08320
gene id: 632335:CALKR_RS08320
uniprot id: E4SA72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

632335:CALKR RS05800
gene id: 632335:CALKR_RS05800
uniprot id: E4S6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS13115
gene id: 632335:CALKR_RS13115
uniprot id: E4S9H0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

632335:CALKR RS02400
gene id: 632335:CALKR_RS02400
uniprot id: E4S9H8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

632335:CALKR RS06570
gene id: 632335:CALKR_RS06570
uniprot id: E4S7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

632335:CALKR RS07145
gene id: 632335:CALKR_RS07145
uniprot id: E4S8U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

632335:CALKR RS10155
gene id: 632335:CALKR_RS10155
uniprot id: E4S564
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

632335:CALKR RS08280
gene id: 632335:CALKR_RS08280
uniprot id: E4SA64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

632335:CALKR RS02550
gene id: 632335:CALKR_RS02550
uniprot id: E4S9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

632335:CALKR RS05220
gene id: 632335:CALKR_RS05220
uniprot id: E4S5N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS02700
gene id: 632335:CALKR_RS02700
uniprot id: E4S9N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632335:CALKR RS04250
gene id: 632335:CALKR_RS04250
uniprot id: E4S4D6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

632335:CALKR RS07025
gene id: 632335:CALKR_RS07025
uniprot id: E4S8R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632335:CALKR RS05890
gene id: 632335:CALKR_RS05890
uniprot id: E4S729
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

632335:CALKR RS02975
gene id: 632335:CALKR_RS02975
uniprot id: E4SA02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

632335:CALKR RS04225
gene id: 632335:CALKR_RS04225
uniprot id: E4S4D1
names: Similarity
messages: Belongs to the CtsR family.

632335:CALKR RS06540
gene id: 632335:CALKR_RS06540
uniprot id: E4S7T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

632335:CALKR RS05725
gene id: 632335:CALKR_RS05725
uniprot id: E4S6P5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

632335:CALKR RS04245
gene id: 632335:CALKR_RS04245
uniprot id: E4S4D5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

632335:CALKR RS09525
gene id: 632335:CALKR_RS09525
uniprot id: E4S4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

632335:CALKR RS02535
gene id: 632335:CALKR_RS02535
uniprot id: E4S9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS04490
gene id: 632335:CALKR_RS04490
uniprot id: E4S4Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

632335:CALKR RS01725
gene id: 632335:CALKR_RS01725
uniprot id: E4S8J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

632335:CALKR RS04700
gene id: 632335:CALKR_RS04700
uniprot id: E4S505
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

632335:CALKR RS04500
gene id: 632335:CALKR_RS04500
uniprot id: E4S4Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

632335:CALKR RS06795
gene id: 632335:CALKR_RS06795
uniprot id: E4S897
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

632335:CALKR RS09230
gene id: 632335:CALKR_RS09230
uniprot id: E4S460
names: Similarity
messages: Belongs to the glycosyl hydrolase.

632335:CALKR RS04290
gene id: 632335:CALKR_RS04290
uniprot id: E4S4E4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS10265
gene id: 632335:CALKR_RS10265
uniprot id: E4S585
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

632335:CALKR RS09725
gene id: 632335:CALKR_RS09725
uniprot id: E4S4L7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS08965
gene id: 632335:CALKR_RS08965
uniprot id: E4SAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS02405
gene id: 632335:CALKR_RS02405
uniprot id: E4S9H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

632335:CALKR RS08700
gene id: 632335:CALKR_RS08700
uniprot id: E4SAJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

632335:CALKR RS05825
gene id: 632335:CALKR_RS05825
uniprot id: E4S6R5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

632335:CALKR RS07335
gene id: 632335:CALKR_RS07335
uniprot id: E4S9A8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

632335:CALKR RS04280
gene id: 632335:CALKR_RS04280
uniprot id: E4S4E2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

632335:CALKR RS05150
gene id: 632335:CALKR_RS05150
uniprot id: E4S5L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

632335:CALKR RS11780
gene id: 632335:CALKR_RS11780
uniprot id: E4S7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS06210
gene id: 632335:CALKR_RS06210
uniprot id: E4S7L7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

632335:CALKR RS11030
gene id: 632335:CALKR_RS11030
uniprot id: E4S6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

632335:CALKR RS00940
gene id: 632335:CALKR_RS00940
uniprot id: E4S6K0
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

632335:CALKR RS06145
gene id: 632335:CALKR_RS06145
uniprot id: E4S780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

632335:CALKR RS06250
gene id: 632335:CALKR_RS06250
uniprot id: E4S7M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

632335:CALKR RS01970
gene id: 632335:CALKR_RS01970
uniprot id: E4S8N8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

632335:CALKR RS10025
gene id: 632335:CALKR_RS10025
uniprot id: E4S4X1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS09910
gene id: 632335:CALKR_RS09910
uniprot id: E4S4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

632335:CALKR RS06710
gene id: 632335:CALKR_RS06710
uniprot id: E4S881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632335:CALKR RS12205
gene id: 632335:CALKR_RS12205
uniprot id: E4S7Y7
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS08775
gene id: 632335:CALKR_RS08775
uniprot id: E4SAR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

632335:CALKR RS05280
gene id: 632335:CALKR_RS05280
uniprot id: E4S5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

632335:CALKR RS04735
gene id: 632335:CALKR_RS04735
uniprot id: E4S512
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

632335:CALKR RS09570
gene id: 632335:CALKR_RS09570
uniprot id: E4S4I6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS05930
gene id: 632335:CALKR_RS05930
uniprot id: E4S737
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

632335:CALKR RS05200
gene id: 632335:CALKR_RS05200
uniprot id: E4S5M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

632335:CALKR RS03015
gene id: 632335:CALKR_RS03015
uniprot id: E4SA74
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

632335:CALKR RS01995
gene id: 632335:CALKR_RS01995
uniprot id: E4S8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

632335:CALKR RS04355
gene id: 632335:CALKR_RS04355
uniprot id: E4S4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

632335:CALKR RS05590
gene id: 632335:CALKR_RS05590
uniprot id: E4S6L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

632335:CALKR RS03960
gene id: 632335:CALKR_RS03960
uniprot id: E4S415
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

632335:CALKR RS09325
gene id: 632335:CALKR_RS09325
uniprot id: E4S474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS10235
gene id: 632335:CALKR_RS10235
uniprot id: E4S580
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

632335:CALKR RS02015
gene id: 632335:CALKR_RS02015
uniprot id: E4S8P7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

632335:CALKR RS12135
gene id: 632335:CALKR_RS12135
uniprot id: E4S7X3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS06040
gene id: 632335:CALKR_RS06040
uniprot id: E4S759
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

632335:CALKR RS05660
gene id: 632335:CALKR_RS05660
uniprot id: E4S6N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

632335:CALKR RS05530
gene id: 632335:CALKR_RS05530
uniprot id: E4S676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

632335:CALKR RS00115
gene id: 632335:CALKR_RS00115
uniprot id: E4S5F0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

632335:CALKR RS08790
gene id: 632335:CALKR_RS08790
uniprot id: E4SAS0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

632335:CALKR RS02010
gene id: 632335:CALKR_RS02010
uniprot id: E4S8P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

632335:CALKR RS03245
gene id: 632335:CALKR_RS03245
uniprot id: E4SAB3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

632335:CALKR RS00755
gene id: 632335:CALKR_RS00755
uniprot id: E4S6G2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS08735
gene id: 632335:CALKR_RS08735
uniprot id: E4SAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

632335:CALKR RS07015
gene id: 632335:CALKR_RS07015
uniprot id: E4S8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

632335:CALKR RS04895
gene id: 632335:CALKR_RS04895
uniprot id: E4S544
names: Similarity
messages: Belongs to the asp23 family.

632335:CALKR RS07355
gene id: 632335:CALKR_RS07355
uniprot id: E4S9B2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

632335:CALKR RS01860
gene id: 632335:CALKR_RS01860
uniprot id: E4S8M0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

632335:CALKR RS08970
gene id: 632335:CALKR_RS08970
uniprot id: E4SAV6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

632335:CALKR RS11630
gene id: 632335:CALKR_RS11630
uniprot id: E4S796
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS06090
gene id: 632335:CALKR_RS06090
uniprot id: E4S769
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

632335:CALKR RS06415
gene id: 632335:CALKR_RS06415
uniprot id: E4S7Q6
names: Similarity
messages: Belongs to the class-D beta-lactamase family.
messages: Belongs to the transpeptidase family.

632335:CALKR RS06860
gene id: 632335:CALKR_RS06860
uniprot id: E4S8B0
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS05310
gene id: 632335:CALKR_RS05310
uniprot id: E4S5Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

632335:CALKR RS03915
gene id: 632335:CALKR_RS03915
uniprot id: E4S406
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

632335:CALKR RS01975
gene id: 632335:CALKR_RS01975
uniprot id: E4S8N9
names: Similarity
messages: Belongs to the DprA/Smf family.

632335:CALKR RS08685
gene id: 632335:CALKR_RS08685
uniprot id: E4SAJ5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

632335:CALKR RS11810
gene id: 632335:CALKR_RS11810
uniprot id: E4S7C7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

632335:CALKR RS02450
gene id: 632335:CALKR_RS02450
uniprot id: E4S9I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

632335:CALKR RS02200
gene id: 632335:CALKR_RS02200
uniprot id: E4S969
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

632335:CALKR RS09310
gene id: 632335:CALKR_RS09310
uniprot id: E4S471
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS01020
gene id: 632335:CALKR_RS01020
uniprot id: E4S6Z8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632335:CALKR RS12030
gene id: 632335:CALKR_RS12030
uniprot id: E4S7V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

632335:CALKR RS10085
gene id: 632335:CALKR_RS10085
uniprot id: E4S4Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

632335:CALKR RS04740
gene id: 632335:CALKR_RS04740
uniprot id: E4S513
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

632335:CALKR RS12950
gene id: 632335:CALKR_RS12950
uniprot id: E4S919
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

632335:CALKR RS02530
gene id: 632335:CALKR_RS02530
uniprot id: E4S9K3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632335:CALKR RS00800
gene id: 632335:CALKR_RS00800
uniprot id: E4S6H1
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS11775
gene id: 632335:CALKR_RS11775
uniprot id: E4S7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS05100
gene id: 632335:CALKR_RS05100
uniprot id: E4S5K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

632335:CALKR RS07005
gene id: 632335:CALKR_RS07005
uniprot id: E4S8R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

632335:CALKR RS08715
gene id: 632335:CALKR_RS08715
uniprot id: E4SAQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

632335:CALKR RS01645
gene id: 632335:CALKR_RS01645
uniprot id: E4S848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

632335:CALKR RS07955
gene id: 632335:CALKR_RS07955
uniprot id: E4S9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

632335:CALKR RS06595
gene id: 632335:CALKR_RS06595
uniprot id: E4S859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

632335:CALKR RS02155
gene id: 632335:CALKR_RS02155
uniprot id: E4S961
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

632335:CALKR RS02475
gene id: 632335:CALKR_RS02475
uniprot id: E4S9J1
names: Similarity
messages: Belongs to the P(II) protein family.

632335:CALKR RS10620
gene id: 632335:CALKR_RS10620
uniprot id: E4S5S6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

632335:CALKR RS06940
gene id: 632335:CALKR_RS06940
uniprot id: E4S8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

632335:CALKR RS03105
gene id: 632335:CALKR_RS03105
uniprot id: E4SA91
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

632335:CALKR RS09395
gene id: 632335:CALKR_RS09395
uniprot id: E4S488
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS08525
gene id: 632335:CALKR_RS08525
uniprot id: E4SAH1
names: Similarity
messages: Belongs to the TrpF family.

632335:CALKR RS07070
gene id: 632335:CALKR_RS07070
uniprot id: E4S8S8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

632335:CALKR RS06650
gene id: 632335:CALKR_RS06650
uniprot id: E4S870
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

632335:CALKR RS11295
gene id: 632335:CALKR_RS11295
uniprot id: E4S6T3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

632335:CALKR RS00600
gene id: 632335:CALKR_RS00600
uniprot id: E4S624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

632335:CALKR RS02075
gene id: 632335:CALKR_RS02075
uniprot id: E4S945
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

632335:CALKR RS10950
gene id: 632335:CALKR_RS10950
uniprot id: E4S691
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

632335:CALKR RS11255
gene id: 632335:CALKR_RS11255
uniprot id: E4S6F1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632335:CALKR RS08660
gene id: 632335:CALKR_RS08660
uniprot id: E4SAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

632335:CALKR RS12440
gene id: 632335:CALKR_RS12440
uniprot id: E4S8F1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

632335:CALKR RS06620
gene id: 632335:CALKR_RS06620
uniprot id: E4S864
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

632335:CALKR RS02270
gene id: 632335:CALKR_RS02270
uniprot id: E4S983
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

632335:CALKR RS05195
gene id: 632335:CALKR_RS05195
uniprot id: E4S5M8
names: Similarity
messages: Belongs to the ribF family.

632335:CALKR RS02265
gene id: 632335:CALKR_RS02265
uniprot id: E4S982
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS05770
gene id: 632335:CALKR_RS05770
uniprot id: E4S6Q4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

632335:CALKR RS04065
gene id: 632335:CALKR_RS04065
uniprot id: E4S499
names: Similarity
messages: Belongs to the GSP E family.

632335:CALKR RS07885
gene id: 632335:CALKR_RS07885
uniprot id: E4S9T0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

632335:CALKR RS05520
gene id: 632335:CALKR_RS05520
uniprot id: E4S674
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632335:CALKR RS11020
gene id: 632335:CALKR_RS11020
uniprot id: E4S6A5
names: Similarity
messages: Belongs to the PemK/MazF family.

632335:CALKR RS06310
gene id: 632335:CALKR_RS06310
uniprot id: E4S7N6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

632335:CALKR RS01710
gene id: 632335:CALKR_RS01710
uniprot id: E4S856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632335:CALKR RS08430
gene id: 632335:CALKR_RS08430
uniprot id: E4SAF4
names: Similarity
messages: Belongs to the bacterial flagellin family.

632335:CALKR RS01315
gene id: 632335:CALKR_RS01315
uniprot id: E4S7I5
names: Similarity
messages: Belongs to the ComB family.

632335:CALKR RS02080
gene id: 632335:CALKR_RS02080
uniprot id: E4S946
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

632335:CALKR RS07010
gene id: 632335:CALKR_RS07010
uniprot id: E4S8R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

632335:CALKR RS04435
gene id: 632335:CALKR_RS04435
uniprot id: E4S4P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

632335:CALKR RS12150
gene id: 632335:CALKR_RS12150
uniprot id: E4S7X6
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS12315
gene id: 632335:CALKR_RS12315
uniprot id: E4S809
names: Subcellular Location Annotation
messages: Membrane

632335:CALKR RS04790
gene id: 632335:CALKR_RS04790
uniprot id: E4S523
names: Similarity
messages: Belongs to the UPF0102 family.

632335:CALKR RS02945
gene id: 632335:CALKR_RS02945
uniprot id: E4S9Z6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

632335:CALKR RS06970
gene id: 632335:CALKR_RS06970
uniprot id: E4S8Q8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.