630626:EBL RS07360
gene id: 630626:EBL_RS07360
uniprot id: I2B7X3
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

630626:EBL RS08755
gene id: 630626:EBL_RS08755
uniprot id: I2B8Q4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

630626:EBL RS03310
gene id: 630626:EBL_RS03310
uniprot id: I2B5L0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

630626:EBL RS15895
gene id: 630626:EBL_RS15895
uniprot id: I2BCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

630626:EBL RS04945
gene id: 630626:EBL_RS04945
uniprot id: I2B6J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

630626:EBL RS06175
gene id: 630626:EBL_RS06175
uniprot id: I2B786
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS06675
gene id: 630626:EBL_RS06675
uniprot id: I2B7I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Membrane

630626:EBL RS15315
gene id: 630626:EBL_RS15315
uniprot id: I2BCH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS07035
gene id: 630626:EBL_RS07035
uniprot id: I2B7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

630626:EBL RS11620
gene id: 630626:EBL_RS11620
uniprot id: I2BAE0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

630626:EBL RS07705
gene id: 630626:EBL_RS07705
uniprot id: I2B839
names: Similarity
messages: Belongs to the peptidase C40 family.

630626:EBL RS17320
gene id: 630626:EBL_RS17320
uniprot id: I2BDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

630626:EBL RS09665
gene id: 630626:EBL_RS09665
uniprot id: I2B987
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
messages: Interacts with MhpE.

630626:EBL RS06415
gene id: 630626:EBL_RS06415
uniprot id: I2B7D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS17335
gene id: 630626:EBL_RS17335
uniprot id: I2BDM8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

630626:EBL RS00895
gene id: 630626:EBL_RS00895
uniprot id: I2B467
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

630626:EBL RS15215
gene id: 630626:EBL_RS15215
uniprot id: I2BCG2
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

630626:EBL RS18650
gene id: 630626:EBL_RS18650
uniprot id: I2BEC5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS07645
gene id: 630626:EBL_RS07645
uniprot id: I2B827
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

630626:EBL RS04105
gene id: 630626:EBL_RS04105
uniprot id: I2B625
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

630626:EBL RS04080
gene id: 630626:EBL_RS04080
uniprot id: I2B620
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11525
gene id: 630626:EBL_RS11525
uniprot id: I2BAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

630626:EBL RS15825
gene id: 630626:EBL_RS15825
uniprot id: I2BCT0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS13050
gene id: 630626:EBL_RS13050
uniprot id: I2BB74
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

630626:EBL RS11705
gene id: 630626:EBL_RS11705
uniprot id: I2BAF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

630626:EBL RS19215
gene id: 630626:EBL_RS19215
uniprot id: I2BEN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS00270
gene id: 630626:EBL_RS00270
uniprot id: I2B3U2
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.
messages: Monomer.

630626:EBL RS03690
gene id: 630626:EBL_RS03690
uniprot id: I2B5U0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15110
gene id: 630626:EBL_RS15110
uniprot id: I2BCE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

630626:EBL RS04155
gene id: 630626:EBL_RS04155
uniprot id: I2B635
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

630626:EBL RS13700
gene id: 630626:EBL_RS13700
uniprot id: I2BBJ9
names: Similarity
messages: Belongs to the UPF0381 family.

630626:EBL RS11570
gene id: 630626:EBL_RS11570
uniprot id: I2BAD0
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

630626:EBL RS13495
gene id: 630626:EBL_RS13495
uniprot id: I2BBF8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS18205
gene id: 630626:EBL_RS18205
uniprot id: I2BE44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

630626:EBL RS09580
gene id: 630626:EBL_RS09580
uniprot id: I2B970
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

630626:EBL RS03255
gene id: 630626:EBL_RS03255
uniprot id: I2B5J9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08620
gene id: 630626:EBL_RS08620
uniprot id: I2B8M6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

630626:EBL RS16100
gene id: 630626:EBL_RS16100
uniprot id: I2BCY5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS03540
gene id: 630626:EBL_RS03540
uniprot id: I2B5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS13355
gene id: 630626:EBL_RS13355
uniprot id: I2BBD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS13790
gene id: 630626:EBL_RS13790
uniprot id: I2BBL6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

630626:EBL RS02670
gene id: 630626:EBL_RS02670
uniprot id: I2B578
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

630626:EBL RS00820
gene id: 630626:EBL_RS00820
uniprot id: I2B452
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

630626:EBL RS16010
gene id: 630626:EBL_RS16010
uniprot id: I2BCW7
names: Function
names: Similarity
messages: Belongs to the bacterial-type ferredoxin family. FixX subfamily.
messages: Could be a 3Fe-4S cluster-containing protein.

630626:EBL RS08615
gene id: 630626:EBL_RS08615
uniprot id: I2B8M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

630626:EBL RS07850
gene id: 630626:EBL_RS07850
uniprot id: I2B868
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

630626:EBL RS06070
gene id: 630626:EBL_RS06070
uniprot id: I2B765
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS05935
gene id: 630626:EBL_RS05935
uniprot id: I2B737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

630626:EBL RS00725
gene id: 630626:EBL_RS00725
uniprot id: I2B432
names: Function
messages: Required for maximal bacterial cellulose synthesis.

630626:EBL RS14070
gene id: 630626:EBL_RS14070
uniprot id: I2BBS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

630626:EBL RS00755
gene id: 630626:EBL_RS00755
uniprot id: I2B438
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS10340
gene id: 630626:EBL_RS10340
uniprot id: I2B9N2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

630626:EBL RS06925
gene id: 630626:EBL_RS06925
uniprot id: I2B7N8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

630626:EBL RS18930
gene id: 630626:EBL_RS18930
uniprot id: I2BEI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

630626:EBL RS12565
gene id: 630626:EBL_RS12565
uniprot id: I2BAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS02015
gene id: 630626:EBL_RS02015
uniprot id: I2B4T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

630626:EBL RS05810
gene id: 630626:EBL_RS05810
uniprot id: I2B712
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

630626:EBL RS07880
gene id: 630626:EBL_RS07880
uniprot id: I2B874
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

630626:EBL RS15830
gene id: 630626:EBL_RS15830
uniprot id: I2BCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

630626:EBL RS12830
gene id: 630626:EBL_RS12830
uniprot id: I2BB29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

630626:EBL RS15765
gene id: 630626:EBL_RS15765
uniprot id: I2BCR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

630626:EBL RS13875
gene id: 630626:EBL_RS13875
uniprot id: I2BBN5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

630626:EBL RS19375
gene id: 630626:EBL_RS19375
uniprot id: I2BES1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

630626:EBL RS02560
gene id: 630626:EBL_RS02560
uniprot id: I2B554
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

630626:EBL RS00220
gene id: 630626:EBL_RS00220
uniprot id: I2B3T0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

630626:EBL RS04390
gene id: 630626:EBL_RS04390
uniprot id: I2B679
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

630626:EBL RS00930
gene id: 630626:EBL_RS00930
uniprot id: I2B475
names: Similarity
messages: Belongs to the ABC transporter superfamily.

630626:EBL RS03735
gene id: 630626:EBL_RS03735
uniprot id: I2B5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS09155
gene id: 630626:EBL_RS09155
uniprot id: I2B8Y3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

630626:EBL RS09375
gene id: 630626:EBL_RS09375
uniprot id: I2B929
names: Similarity
messages: Belongs to the aspartokinase family.

630626:EBL RS07210
gene id: 630626:EBL_RS07210
uniprot id: I2B7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.
messages: Membrane

630626:EBL RS17170
gene id: 630626:EBL_RS17170
uniprot id: I2BDJ5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS05125
gene id: 630626:EBL_RS05125
uniprot id: I2B6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

630626:EBL RS01520
gene id: 630626:EBL_RS01520
uniprot id: I2B4J7
names: Similarity
messages: Belongs to the DprA/Smf family.

630626:EBL RS06495
gene id: 630626:EBL_RS06495
uniprot id: I2B7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

630626:EBL RS15910
gene id: 630626:EBL_RS15910
uniprot id: I2BCU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08840
gene id: 630626:EBL_RS08840
uniprot id: I2B8S1
names: Similarity
messages: Belongs to the peptidase A31 family.

630626:EBL RS18660
gene id: 630626:EBL_RS18660
uniprot id: I2BEC7
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

630626:EBL RS02875
gene id: 630626:EBL_RS02875
uniprot id: I2B5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS01125
gene id: 630626:EBL_RS01125
uniprot id: I2B4B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

630626:EBL RS05060
gene id: 630626:EBL_RS05060
uniprot id: I2B6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GppA/Ppx family.
messages: Cell membrane
messages: Membrane

630626:EBL RS16025
gene id: 630626:EBL_RS16025
uniprot id: I2BCX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of FixA and FixB.
messages: Required for anaerobic carnitine reduction. May bring reductant to CaiA.

630626:EBL RS05160
gene id: 630626:EBL_RS05160
uniprot id: I2B6N6
names: Similarity
messages: Belongs to the ArsC family.

630626:EBL RS15945
gene id: 630626:EBL_RS15945
uniprot id: I2BCV4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

630626:EBL RS10410
gene id: 630626:EBL_RS10410
uniprot id: I2B9P6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

630626:EBL RS01510
gene id: 630626:EBL_RS01510
uniprot id: I2B4J5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

630626:EBL RS16185
gene id: 630626:EBL_RS16185
uniprot id: I2BD02
names: Similarity
messages: Belongs to the UPF0246 family.

630626:EBL RS15375
gene id: 630626:EBL_RS15375
uniprot id: I2BCI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

630626:EBL RS14685
gene id: 630626:EBL_RS14685
uniprot id: I2BC52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS05065
gene id: 630626:EBL_RS05065
uniprot id: I2B6L5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

630626:EBL RS05865
gene id: 630626:EBL_RS05865
uniprot id: I2B723
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

630626:EBL RS13425
gene id: 630626:EBL_RS13425
uniprot id: I2BBE5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15255
gene id: 630626:EBL_RS15255
uniprot id: I2BCH0
names: Subunit
messages: Monomer.

630626:EBL RS17555
gene id: 630626:EBL_RS17555
uniprot id: I2BDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS06180
gene id: 630626:EBL_RS06180
uniprot id: I2B787
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

630626:EBL RS09170
gene id: 630626:EBL_RS09170
uniprot id: I2B8Y6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS14200
gene id: 630626:EBL_RS14200
uniprot id: I2BBV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS04670
gene id: 630626:EBL_RS04670
uniprot id: I2B6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS18925
gene id: 630626:EBL_RS18925
uniprot id: I2BEI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

630626:EBL RS02245
gene id: 630626:EBL_RS02245
uniprot id: I2B4Y5
names: Similarity
messages: Belongs to the UxaA family.

630626:EBL RS15790
gene id: 630626:EBL_RS15790
uniprot id: I2BCS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

630626:EBL RS08910
gene id: 630626:EBL_RS08910
uniprot id: I2B8T5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Homotetramer.
messages: Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.

630626:EBL RS09040
gene id: 630626:EBL_RS09040
uniprot id: I2B8W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

630626:EBL RS11610
gene id: 630626:EBL_RS11610
uniprot id: I2BAD8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

630626:EBL RS04920
gene id: 630626:EBL_RS04920
uniprot id: I2B6I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

630626:EBL RS11365
gene id: 630626:EBL_RS11365
uniprot id: I2BA88
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

630626:EBL RS12355
gene id: 630626:EBL_RS12355
uniprot id: I2BAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS12900
gene id: 630626:EBL_RS12900
uniprot id: I2BB44
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

630626:EBL RS00370
gene id: 630626:EBL_RS00370
uniprot id: I2B3W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS15695
gene id: 630626:EBL_RS15695
uniprot id: I2BCQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

630626:EBL RS16940
gene id: 630626:EBL_RS16940
uniprot id: I2BDE8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

630626:EBL RS18675
gene id: 630626:EBL_RS18675
uniprot id: I2BED1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

630626:EBL RS18475
gene id: 630626:EBL_RS18475
uniprot id: I2BE95
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

630626:EBL RS17410
gene id: 630626:EBL_RS17410
uniprot id: I2BDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell inner membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

630626:EBL RS14085
gene id: 630626:EBL_RS14085
uniprot id: I2BBS8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

630626:EBL RS06150
gene id: 630626:EBL_RS06150
uniprot id: I2B781
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family. RNase BN subfamily.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.

630626:EBL RS01840
gene id: 630626:EBL_RS01840
uniprot id: I2B4Q5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS09605
gene id: 630626:EBL_RS09605
uniprot id: I2B974
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

630626:EBL RS06380
gene id: 630626:EBL_RS06380
uniprot id: I2B7C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

630626:EBL RS07945
gene id: 630626:EBL_RS07945
uniprot id: I2B887
names: Similarity
messages: Belongs to the PspA/IM30 family.

630626:EBL RS12785
gene id: 630626:EBL_RS12785
uniprot id: I2BB27
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06215
gene id: 630626:EBL_RS06215
uniprot id: I2B795
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

630626:EBL RS10180
gene id: 630626:EBL_RS10180
uniprot id: I2B9K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

630626:EBL RS03870
gene id: 630626:EBL_RS03870
uniprot id: I2B5X8
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

630626:EBL RS12515
gene id: 630626:EBL_RS12515
uniprot id: I2BAW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

630626:EBL RS08610
gene id: 630626:EBL_RS08610
uniprot id: I2B8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

630626:EBL RS17630
gene id: 630626:EBL_RS17630
uniprot id: I2BDT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS19195
gene id: 630626:EBL_RS19195
uniprot id: I2BEN3
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

630626:EBL RS12340
gene id: 630626:EBL_RS12340
uniprot id: I2BAT3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

630626:EBL RS00070
gene id: 630626:EBL_RS00070
uniprot id: I2B3P7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11375
gene id: 630626:EBL_RS11375
uniprot id: I2BA90
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

630626:EBL RS19105
gene id: 630626:EBL_RS19105
uniprot id: I2BEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

630626:EBL RS17480
gene id: 630626:EBL_RS17480
uniprot id: I2BDQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

630626:EBL RS04345
gene id: 630626:EBL_RS04345
uniprot id: I2B669
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS14945
gene id: 630626:EBL_RS14945
uniprot id: I2BCA7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

630626:EBL RS08110
gene id: 630626:EBL_RS08110
uniprot id: I2B8C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

630626:EBL RS05030
gene id: 630626:EBL_RS05030
uniprot id: I2B6K8
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

630626:EBL RS04875
gene id: 630626:EBL_RS04875
uniprot id: I2B6H7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS12940
gene id: 630626:EBL_RS12940
uniprot id: I2BB52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.
messages: Toroid-shaped homohexamer. In the hexamer, 3 dimers assemble to form a ring-like structure surrounding a central hole.

630626:EBL RS11655
gene id: 630626:EBL_RS11655
uniprot id: I2BAE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

630626:EBL RS00875
gene id: 630626:EBL_RS00875
uniprot id: I2B463
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

630626:EBL RS02645
gene id: 630626:EBL_RS02645
uniprot id: I2B573
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

630626:EBL RS00490
gene id: 630626:EBL_RS00490
uniprot id: I2B3Y6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS05930
gene id: 630626:EBL_RS05930
uniprot id: I2B736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

630626:EBL RS01630
gene id: 630626:EBL_RS01630
uniprot id: I2B4L2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

630626:EBL RS06115
gene id: 630626:EBL_RS06115
uniprot id: I2B774
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS07700
gene id: 630626:EBL_RS07700
uniprot id: I2B838
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

630626:EBL RS10915
gene id: 630626:EBL_RS10915
uniprot id: I2B9Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

630626:EBL RS15480
gene id: 630626:EBL_RS15480
uniprot id: I2BCL0
names: Similarity
messages: Belongs to the CdaR family.

630626:EBL RS07830
gene id: 630626:EBL_RS07830
uniprot id: I2B864
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

630626:EBL RS01600
gene id: 630626:EBL_RS01600
uniprot id: I2B4K6
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

630626:EBL RS09700
gene id: 630626:EBL_RS09700
uniprot id: I2B994
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

630626:EBL RS06750
gene id: 630626:EBL_RS06750
uniprot id: I2B7K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

630626:EBL RS14140
gene id: 630626:EBL_RS14140
uniprot id: I2BBT9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS00775
gene id: 630626:EBL_RS00775
uniprot id: I2B442
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

630626:EBL RS02740
gene id: 630626:EBL_RS02740
uniprot id: I2B592
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

630626:EBL RS16665
gene id: 630626:EBL_RS16665
uniprot id: I2BD93
names: Subcellular Location Annotation
messages: Cell outer membrane

630626:EBL RS01380
gene id: 630626:EBL_RS01380
uniprot id: I2B4G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

630626:EBL RS06595
gene id: 630626:EBL_RS06595
uniprot id: I2B7H1
names: Similarity
messages: Belongs to the peptidase S11 family.

630626:EBL RS03585
gene id: 630626:EBL_RS03585
uniprot id: I2B5R9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

630626:EBL RS19170
gene id: 630626:EBL_RS19170
uniprot id: I2BEM8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS02870
gene id: 630626:EBL_RS02870
uniprot id: I2B5B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

630626:EBL RS01155
gene id: 630626:EBL_RS01155
uniprot id: I2B4C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS01150
gene id: 630626:EBL_RS01150
uniprot id: I2B4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS09760
gene id: 630626:EBL_RS09760
uniprot id: I2B9A7
names: Function
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA.

630626:EBL RS12560
gene id: 630626:EBL_RS12560
uniprot id: I2BAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

630626:EBL RS02345
gene id: 630626:EBL_RS02345
uniprot id: I2B509
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS15935
gene id: 630626:EBL_RS15935
uniprot id: I2BCV2
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

630626:EBL RS04130
gene id: 630626:EBL_RS04130
uniprot id: I2B630
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

630626:EBL RS14015
gene id: 630626:EBL_RS14015
uniprot id: I2BBR4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

630626:EBL RS02105
gene id: 630626:EBL_RS02105
uniprot id: I2B4V7
names: Similarity
messages: Belongs to the UPF0306 family.

630626:EBL RS15350
gene id: 630626:EBL_RS15350
uniprot id: I2BCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

630626:EBL RS19435
gene id: 630626:EBL_RS19435
uniprot id: I2BET3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

630626:EBL RS09080
gene id: 630626:EBL_RS09080
uniprot id: I2B8X0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

630626:EBL RS15880
gene id: 630626:EBL_RS15880
uniprot id: I2BCU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

630626:EBL RS11420
gene id: 630626:EBL_RS11420
uniprot id: I2BA99
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

630626:EBL RS06915
gene id: 630626:EBL_RS06915
uniprot id: I2B7N6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

630626:EBL RS05805
gene id: 630626:EBL_RS05805
uniprot id: I2B711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS07030
gene id: 630626:EBL_RS07030
uniprot id: I2B7Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

630626:EBL RS00980
gene id: 630626:EBL_RS00980
uniprot id: I2B485
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

630626:EBL RS18555
gene id: 630626:EBL_RS18555
uniprot id: I2BEA6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

630626:EBL RS13305
gene id: 630626:EBL_RS13305
uniprot id: I2BBB9
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Membrane
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

630626:EBL RS08495
gene id: 630626:EBL_RS08495
uniprot id: I2B8K1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

630626:EBL RS15470
gene id: 630626:EBL_RS15470
uniprot id: I2BCK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

630626:EBL RS13950
gene id: 630626:EBL_RS13950
uniprot id: I2BBQ0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

630626:EBL RS07180
gene id: 630626:EBL_RS07180
uniprot id: I2B7T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

630626:EBL RS01785
gene id: 630626:EBL_RS01785
uniprot id: K6UTC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

630626:EBL RS03260
gene id: 630626:EBL_RS03260
uniprot id: I2B5K0
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.
messages: Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

630626:EBL RS17625
gene id: 630626:EBL_RS17625
uniprot id: I2BDT5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS10955
gene id: 630626:EBL_RS10955
uniprot id: I2BA07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

630626:EBL RS02745
gene id: 630626:EBL_RS02745
uniprot id: I2B593
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

630626:EBL RS11675
gene id: 630626:EBL_RS11675
uniprot id: I2BAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS18620
gene id: 630626:EBL_RS18620
uniprot id: I2BEB9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS01185
gene id: 630626:EBL_RS01185
uniprot id: I2B4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS18680
gene id: 630626:EBL_RS18680
uniprot id: I2BED2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

630626:EBL RS00735
gene id: 630626:EBL_RS00735
uniprot id: I2B434
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

630626:EBL RS18365
gene id: 630626:EBL_RS18365
uniprot id: I2BE73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

630626:EBL RS02155
gene id: 630626:EBL_RS02155
uniprot id: I2B4W7
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

630626:EBL RS03560
gene id: 630626:EBL_RS03560
uniprot id: I2B5R4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

630626:EBL RS12955
gene id: 630626:EBL_RS12955
uniprot id: I2BB55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

630626:EBL RS15585
gene id: 630626:EBL_RS15585
uniprot id: I2BCN1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

630626:EBL RS03785
gene id: 630626:EBL_RS03785
uniprot id: I2B5V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

630626:EBL RS12640
gene id: 630626:EBL_RS12640
uniprot id: I2BAZ4
names: Similarity
messages: Belongs to the MoaD family.

630626:EBL RS02750
gene id: 630626:EBL_RS02750
uniprot id: I2B594
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

630626:EBL RS12375
gene id: 630626:EBL_RS12375
uniprot id: I2BAU0
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

630626:EBL RS12065
gene id: 630626:EBL_RS12065
uniprot id: I2BAM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

630626:EBL RS15495
gene id: 630626:EBL_RS15495
uniprot id: I2BCL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

630626:EBL RS11985
gene id: 630626:EBL_RS11985
uniprot id: I2BAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

630626:EBL RS13545
gene id: 630626:EBL_RS13545
uniprot id: I2BBG8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

630626:EBL RS00455
gene id: 630626:EBL_RS00455
uniprot id: I2B3X9
names: Similarity
messages: Belongs to the HypD family.

630626:EBL RS13605
gene id: 630626:EBL_RS13605
uniprot id: I2BBI0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

630626:EBL RS13345
gene id: 630626:EBL_RS13345
uniprot id: I2BBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS08530
gene id: 630626:EBL_RS08530
uniprot id: I2B8K8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

630626:EBL RS03830
gene id: 630626:EBL_RS03830
uniprot id: I2B5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

630626:EBL RS07165
gene id: 630626:EBL_RS07165
uniprot id: K6VTW1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

630626:EBL RS03665
gene id: 630626:EBL_RS03665
uniprot id: I2B5T5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS18165
gene id: 630626:EBL_RS18165
uniprot id: I2BE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS08895
gene id: 630626:EBL_RS08895
uniprot id: I2B8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS12685
gene id: 630626:EBL_RS12685
uniprot id: I2BB04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS00885
gene id: 630626:EBL_RS00885
uniprot id: I2B465
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

630626:EBL RS04640
gene id: 630626:EBL_RS04640
uniprot id: I2B6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

630626:EBL RS04720
gene id: 630626:EBL_RS04720
uniprot id: I2B6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

630626:EBL RS15555
gene id: 630626:EBL_RS15555
uniprot id: I2BCM5
names: Similarity
messages: Belongs to the SfsA family.

630626:EBL RS02195
gene id: 630626:EBL_RS02195
uniprot id: I2B4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

630626:EBL RS17180
gene id: 630626:EBL_RS17180
uniprot id: I2BDJ7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

630626:EBL RS17295
gene id: 630626:EBL_RS17295
uniprot id: I2BDM0
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

630626:EBL RS17960
gene id: 630626:EBL_RS17960
uniprot id: I2BE02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

630626:EBL RS12535
gene id: 630626:EBL_RS12535
uniprot id: I2BAX2
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS12170
gene id: 630626:EBL_RS12170
uniprot id: I2BAP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS09365
gene id: 630626:EBL_RS09365
uniprot id: I2B927
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS17400
gene id: 630626:EBL_RS17400
uniprot id: I2BDN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

630626:EBL RS08410
gene id: 630626:EBL_RS08410
uniprot id: I2B8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

630626:EBL RS18305
gene id: 630626:EBL_RS18305
uniprot id: I2BE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

630626:EBL RS00300
gene id: 630626:EBL_RS00300
uniprot id: I2B3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

630626:EBL RS15140
gene id: 630626:EBL_RS15140
uniprot id: I2BCE7
names: Similarity
messages: Belongs to the YkuD family.

630626:EBL RS17965
gene id: 630626:EBL_RS17965
uniprot id: I2BE03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS06080
gene id: 630626:EBL_RS06080
uniprot id: I2B767
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS04400
gene id: 630626:EBL_RS04400
uniprot id: I2B683
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS09785
gene id: 630626:EBL_RS09785
uniprot id: I2B9B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

630626:EBL RS12210
gene id: 630626:EBL_RS12210
uniprot id: I2BAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

630626:EBL RS01895
gene id: 630626:EBL_RS01895
uniprot id: I2B4R6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

630626:EBL RS12555
gene id: 630626:EBL_RS12555
uniprot id: I2BAX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

630626:EBL RS06905
gene id: 630626:EBL_RS06905
uniprot id: I2B7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS09805
gene id: 630626:EBL_RS09805
uniprot id: I2B9B6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

630626:EBL RS02025
gene id: 630626:EBL_RS02025
uniprot id: I2B4U1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

630626:EBL RS04530
gene id: 630626:EBL_RS04530
uniprot id: I2B6A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS16485
gene id: 630626:EBL_RS16485
uniprot id: I2BD61
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
messages: Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion.

630626:EBL RS00015
gene id: 630626:EBL_RS00015
uniprot id: I2B3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

630626:EBL RS12780
gene id: 630626:EBL_RS12780
uniprot id: I2BB26
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

630626:EBL RS17535
gene id: 630626:EBL_RS17535
uniprot id: I2BDR6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15150
gene id: 630626:EBL_RS15150
uniprot id: I2BCE9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

630626:EBL RS04625
gene id: 630626:EBL_RS04625
uniprot id: I2B6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

630626:EBL RS01745
gene id: 630626:EBL_RS01745
uniprot id: I2B4N5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

630626:EBL RS12760
gene id: 630626:EBL_RS12760
uniprot id: I2BB22
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

630626:EBL RS10290
gene id: 630626:EBL_RS10290
uniprot id: I2B9M2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS19540
gene id: 630626:EBL_RS19540
uniprot id: I2B4I3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

630626:EBL RS18665
gene id: 630626:EBL_RS18665
uniprot id: I2BEC8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

630626:EBL RS00785
gene id: 630626:EBL_RS00785
uniprot id: I2B444
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS14780
gene id: 630626:EBL_RS14780
uniprot id: I2BC71
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS01515
gene id: 630626:EBL_RS01515
uniprot id: I2B4J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

630626:EBL RS01300
gene id: 630626:EBL_RS01300
uniprot id: I2B4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

630626:EBL RS09275
gene id: 630626:EBL_RS09275
uniprot id: I2B908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS02055
gene id: 630626:EBL_RS02055
uniprot id: I2B4U7
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

630626:EBL RS18025
gene id: 630626:EBL_RS18025
uniprot id: I2BE15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

630626:EBL RS07310
gene id: 630626:EBL_RS07310
uniprot id: I2B7W4
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS04785
gene id: 630626:EBL_RS04785
uniprot id: I2B6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

630626:EBL RS13755
gene id: 630626:EBL_RS13755
uniprot id: I2BBK9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

630626:EBL RS11400
gene id: 630626:EBL_RS11400
uniprot id: I2BA95
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS14795
gene id: 630626:EBL_RS14795
uniprot id: I2BC74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Belongs to the glutarate hydroxylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Homotetramer.

630626:EBL RS06790
gene id: 630626:EBL_RS06790
uniprot id: I2B7L0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

630626:EBL RS05255
gene id: 630626:EBL_RS05255
uniprot id: I2B6Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

630626:EBL RS18425
gene id: 630626:EBL_RS18425
uniprot id: I2BE85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

630626:EBL RS07575
gene id: 630626:EBL_RS07575
uniprot id: I2B813
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

630626:EBL RS13960
gene id: 630626:EBL_RS13960
uniprot id: I2BBQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

630626:EBL RS17380
gene id: 630626:EBL_RS17380
uniprot id: I2BDN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

630626:EBL RS16135
gene id: 630626:EBL_RS16135
uniprot id: I2BCZ2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

630626:EBL RS15805
gene id: 630626:EBL_RS15805
uniprot id: I2BCS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

630626:EBL RS12135
gene id: 630626:EBL_RS12135
uniprot id: I2BAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS04325
gene id: 630626:EBL_RS04325
uniprot id: I2B665
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

630626:EBL RS15785
gene id: 630626:EBL_RS15785
uniprot id: I2BCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

630626:EBL RS04775
gene id: 630626:EBL_RS04775
uniprot id: I2B6F4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

630626:EBL RS06130
gene id: 630626:EBL_RS06130
uniprot id: I2B777
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

630626:EBL RS01525
gene id: 630626:EBL_RS01525
uniprot id: I2B4J8
names: Similarity
messages: Belongs to the Smg family.

630626:EBL RS03935
gene id: 630626:EBL_RS03935
uniprot id: I2B5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

630626:EBL RS05230
gene id: 630626:EBL_RS05230
uniprot id: I2B6Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

630626:EBL RS19015
gene id: 630626:EBL_RS19015
uniprot id: I2BEK0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS18125
gene id: 630626:EBL_RS18125
uniprot id: I2BE28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

630626:EBL RS19160
gene id: 630626:EBL_RS19160
uniprot id: I2BEM6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

630626:EBL RS19240
gene id: 630626:EBL_RS19240
uniprot id: I2BEP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

630626:EBL RS00470
gene id: 630626:EBL_RS00470
uniprot id: I2B3Y2
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

630626:EBL RS04275
gene id: 630626:EBL_RS04275
uniprot id: I2B660
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS01605
gene id: 630626:EBL_RS01605
uniprot id: I2B4K7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

630626:EBL RS18020
gene id: 630626:EBL_RS18020
uniprot id: I2BE14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

630626:EBL RS01030
gene id: 630626:EBL_RS01030
uniprot id: I2B495
names: Similarity
messages: Belongs to the disproportionating enzyme family.

630626:EBL RS11940
gene id: 630626:EBL_RS11940
uniprot id: I2BAK2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

630626:EBL RS12655
gene id: 630626:EBL_RS12655
uniprot id: I2BAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

630626:EBL RS01740
gene id: 630626:EBL_RS01740
uniprot id: I2B4N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

630626:EBL RS07930
gene id: 630626:EBL_RS07930
uniprot id: I2B884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS02700
gene id: 630626:EBL_RS02700
uniprot id: I2B584
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

630626:EBL RS18725
gene id: 630626:EBL_RS18725
uniprot id: I2BEE1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

630626:EBL RS11260
gene id: 630626:EBL_RS11260
uniprot id: I2BA66
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

630626:EBL RS12925
gene id: 630626:EBL_RS12925
uniprot id: I2BB49
names: Similarity
messages: Belongs to the FPG family.

630626:EBL RS17135
gene id: 630626:EBL_RS17135
uniprot id: I2BDI8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS00805
gene id: 630626:EBL_RS00805
uniprot id: I2B449
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

630626:EBL RS15250
gene id: 630626:EBL_RS15250
uniprot id: I2BCG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS07680
gene id: 630626:EBL_RS07680
uniprot id: I2B834
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS17820
gene id: 630626:EBL_RS17820
uniprot id: I2BDX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS16120
gene id: 630626:EBL_RS16120
uniprot id: I2BCY9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

630626:EBL RS16525
gene id: 630626:EBL_RS16525
uniprot id: I2BD69
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS18820
gene id: 630626:EBL_RS18820
uniprot id: I2BEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

630626:EBL RS02035
gene id: 630626:EBL_RS02035
uniprot id: I2B4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

630626:EBL RS11345
gene id: 630626:EBL_RS11345
uniprot id: I2BA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

630626:EBL RS02715
gene id: 630626:EBL_RS02715
uniprot id: I2B587
names: Similarity
messages: Belongs to the UPF0235 family.

630626:EBL RS00010
gene id: 630626:EBL_RS00010
uniprot id: I2B3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

630626:EBL RS14845
gene id: 630626:EBL_RS14845
uniprot id: I2BC87
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

630626:EBL RS05135
gene id: 630626:EBL_RS05135
uniprot id: I2B6N1
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS10405
gene id: 630626:EBL_RS10405
uniprot id: I2B9P5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

630626:EBL RS05950
gene id: 630626:EBL_RS05950
uniprot id: I2B740
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

630626:EBL RS16275
gene id: 630626:EBL_RS16275
uniprot id: I2BD20
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

630626:EBL RS13225
gene id: 630626:EBL_RS13225
uniprot id: I2BBA1
names: Similarity
messages: Belongs to the UPF0250 family.

630626:EBL RS05305
gene id: 630626:EBL_RS05305
uniprot id: I2B6R6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS13400
gene id: 630626:EBL_RS13400
uniprot id: I2BBE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

630626:EBL RS05910
gene id: 630626:EBL_RS05910
uniprot id: I2B732
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

630626:EBL RS15735
gene id: 630626:EBL_RS15735
uniprot id: I2BCR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

630626:EBL RS02985
gene id: 630626:EBL_RS02985
uniprot id: I2B5E2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

630626:EBL RS03950
gene id: 630626:EBL_RS03950
uniprot id: I2B5Z2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

630626:EBL RS07925
gene id: 630626:EBL_RS07925
uniprot id: I2B883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

630626:EBL RS13125
gene id: 630626:EBL_RS13125
uniprot id: I2BB81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

630626:EBL RS18855
gene id: 630626:EBL_RS18855
uniprot id: I2BEG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

630626:EBL RS14985
gene id: 630626:EBL_RS14985
uniprot id: I2BCB5
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

630626:EBL RS03105
gene id: 630626:EBL_RS03105
uniprot id: I2B5G7
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS12985
gene id: 630626:EBL_RS12985
uniprot id: I2BB61
names: Similarity
messages: Belongs to the phosphohexose mutase family.

630626:EBL RS08535
gene id: 630626:EBL_RS08535
uniprot id: I2B8K9
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

630626:EBL RS09830
gene id: 630626:EBL_RS09830
uniprot id: I2B9C2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

630626:EBL RS12755
gene id: 630626:EBL_RS12755
uniprot id: I2BB21
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

630626:EBL RS17565
gene id: 630626:EBL_RS17565
uniprot id: I2BDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

630626:EBL RS06550
gene id: 630626:EBL_RS06550
uniprot id: I2B7G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS01950
gene id: 630626:EBL_RS01950
uniprot id: I2B4S7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

630626:EBL RS14995
gene id: 630626:EBL_RS14995
uniprot id: I2BCB7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

630626:EBL RS18935
gene id: 630626:EBL_RS18935
uniprot id: I2BEI3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

630626:EBL RS01710
gene id: 630626:EBL_RS01710
uniprot id: I2B4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

630626:EBL RS04140
gene id: 630626:EBL_RS04140
uniprot id: I2B632
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

630626:EBL RS15550
gene id: 630626:EBL_RS15550
uniprot id: I2BCM4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

630626:EBL RS17420
gene id: 630626:EBL_RS17420
uniprot id: I2BDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS15940
gene id: 630626:EBL_RS15940
uniprot id: I2BCV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

630626:EBL RS19440
gene id: 630626:EBL_RS19440
uniprot id: I2BET4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

630626:EBL RS10380
gene id: 630626:EBL_RS10380
uniprot id: I2B9P0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

630626:EBL RS10850
gene id: 630626:EBL_RS10850
uniprot id: I2B9Y4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

630626:EBL RS11895
gene id: 630626:EBL_RS11895
uniprot id: I2BAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

630626:EBL RS17385
gene id: 630626:EBL_RS17385
uniprot id: I2BDN5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

630626:EBL RS19120
gene id: 630626:EBL_RS19120
uniprot id: I2BEM1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

630626:EBL RS08095
gene id: 630626:EBL_RS08095
uniprot id: I2B8B8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

630626:EBL RS18385
gene id: 630626:EBL_RS18385
uniprot id: I2BE77
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

630626:EBL RS16110
gene id: 630626:EBL_RS16110
uniprot id: I2BCY7
names: Similarity
messages: Belongs to the DapA family.

630626:EBL RS12305
gene id: 630626:EBL_RS12305
uniprot id: I2BAS6
names: Similarity
messages: Belongs to the UPF0145 family.

630626:EBL RS12245
gene id: 630626:EBL_RS12245
uniprot id: I2BAR4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

630626:EBL RS05800
gene id: 630626:EBL_RS05800
uniprot id: I2B710
names: Similarity
messages: Belongs to the MlaA family.

630626:EBL RS12045
gene id: 630626:EBL_RS12045
uniprot id: I2BAM4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

630626:EBL RS04360
gene id: 630626:EBL_RS04360
uniprot id: I2B672
names: Similarity
messages: Belongs to the ABC transporter superfamily.

630626:EBL RS08040
gene id: 630626:EBL_RS08040
uniprot id: I2B8A6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

630626:EBL RS18700
gene id: 630626:EBL_RS18700
uniprot id: I2BED6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

630626:EBL RS02720
gene id: 630626:EBL_RS02720
uniprot id: I2B588
names: Similarity
messages: Belongs to the YggT family.

630626:EBL RS09140
gene id: 630626:EBL_RS09140
uniprot id: I2B8Y0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

630626:EBL RS01905
gene id: 630626:EBL_RS01905
uniprot id: I2B4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS18250
gene id: 630626:EBL_RS18250
uniprot id: I2BE53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

630626:EBL RS02955
gene id: 630626:EBL_RS02955
uniprot id: I2B5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

630626:EBL RS16995
gene id: 630626:EBL_RS16995
uniprot id: I2BDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

630626:EBL RS10740
gene id: 630626:EBL_RS10740
uniprot id: I2B9W2
names: Similarity
messages: Belongs to the peptidase S1B family.

630626:EBL RS07430
gene id: 630626:EBL_RS07430
uniprot id: I2B7Y6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

630626:EBL RS01095
gene id: 630626:EBL_RS01095
uniprot id: I2B4A9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

630626:EBL RS15245
gene id: 630626:EBL_RS15245
uniprot id: I2BCG8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS12730
gene id: 630626:EBL_RS12730
uniprot id: I2BB16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

630626:EBL RS16915
gene id: 630626:EBL_RS16915
uniprot id: I2BDE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

630626:EBL RS17255
gene id: 630626:EBL_RS17255
uniprot id: I2BDL2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

630626:EBL RS01695
gene id: 630626:EBL_RS01695
uniprot id: I2B4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

630626:EBL RS15925
gene id: 630626:EBL_RS15925
uniprot id: I2BCV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

630626:EBL RS06670
gene id: 630626:EBL_RS06670
uniprot id: I2B7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS02695
gene id: 630626:EBL_RS02695
uniprot id: I2B583
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

630626:EBL RS10845
gene id: 630626:EBL_RS10845
uniprot id: I2B9Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

630626:EBL RS01110
gene id: 630626:EBL_RS01110
uniprot id: I2B4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS16255
gene id: 630626:EBL_RS16255
uniprot id: I2BD16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS05225
gene id: 630626:EBL_RS05225
uniprot id: I2B6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

630626:EBL RS12100
gene id: 630626:EBL_RS12100
uniprot id: I2BAN5
names: Similarity
messages: Belongs to the UPF0434 family.

630626:EBL RS17850
gene id: 630626:EBL_RS17850
uniprot id: I2BDY4
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine synthase RsuA family.
messages: Monomer.

630626:EBL RS16180
gene id: 630626:EBL_RS16180
uniprot id: I2BD01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS03465
gene id: 630626:EBL_RS03465
uniprot id: I2B5P4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

630626:EBL RS03930
gene id: 630626:EBL_RS03930
uniprot id: I2B5Y8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS08850
gene id: 630626:EBL_RS08850
uniprot id: I2B8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

630626:EBL RS00790
gene id: 630626:EBL_RS00790
uniprot id: I2B446
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

630626:EBL RS11455
gene id: 630626:EBL_RS11455
uniprot id: I2BAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

630626:EBL RS06030
gene id: 630626:EBL_RS06030
uniprot id: I2B756
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

630626:EBL RS09160
gene id: 630626:EBL_RS09160
uniprot id: I2B8Y4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

630626:EBL RS04695
gene id: 630626:EBL_RS04695
uniprot id: I2B6D7
names: Similarity
messages: Belongs to the thioredoxin family.

630626:EBL RS04730
gene id: 630626:EBL_RS04730
uniprot id: I2B6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

630626:EBL RS04855
gene id: 630626:EBL_RS04855
uniprot id: I2B6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS16270
gene id: 630626:EBL_RS16270
uniprot id: I2BD19
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

630626:EBL RS14090
gene id: 630626:EBL_RS14090
uniprot id: I2BBS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

630626:EBL RS11380
gene id: 630626:EBL_RS11380
uniprot id: I2BA91
names: Similarity
messages: Belongs to the MipA/OmpV family.

630626:EBL RS05420
gene id: 630626:EBL_RS05420
uniprot id: I2B6T3
names: Similarity
messages: To H.influenzae HI_0842.

630626:EBL RS17290
gene id: 630626:EBL_RS17290
uniprot id: I2BDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS01750
gene id: 630626:EBL_RS01750
uniprot id: I2B4N6
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

630626:EBL RS11075
gene id: 630626:EBL_RS11075
uniprot id: I2BA31
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS16990
gene id: 630626:EBL_RS16990
uniprot id: I2BDF8
names: Similarity
names: Subunit
messages: Belongs to the RutC family.
messages: Homotrimer.

630626:EBL RS08735
gene id: 630626:EBL_RS08735
uniprot id: I2B8Q0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

630626:EBL RS03485
gene id: 630626:EBL_RS03485
uniprot id: I2B5P9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS07305
gene id: 630626:EBL_RS07305
uniprot id: I2B7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS13985
gene id: 630626:EBL_RS13985
uniprot id: I2BBQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

630626:EBL RS04895
gene id: 630626:EBL_RS04895
uniprot id: I2B6I1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

630626:EBL RS14030
gene id: 630626:EBL_RS14030
uniprot id: I2BBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

630626:EBL RS06505
gene id: 630626:EBL_RS06505
uniprot id: I2B7F3
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS05035
gene id: 630626:EBL_RS05035
uniprot id: I2B6K9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

630626:EBL RS15845
gene id: 630626:EBL_RS15845
uniprot id: I2BCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

630626:EBL RS01065
gene id: 630626:EBL_RS01065
uniprot id: I2B4A2
names: Similarity
messages: Belongs to the FeoA family.

630626:EBL RS11275
gene id: 630626:EBL_RS11275
uniprot id: I2BA69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS11480
gene id: 630626:EBL_RS11480
uniprot id: I2BAB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

630626:EBL RS01400
gene id: 630626:EBL_RS01400
uniprot id: I2B4H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

630626:EBL RS01405
gene id: 630626:EBL_RS01405
uniprot id: I2B4H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

630626:EBL RS18270
gene id: 630626:EBL_RS18270
uniprot id: I2BE57
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

630626:EBL RS16300
gene id: 630626:EBL_RS16300
uniprot id: I2BD25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

630626:EBL RS15835
gene id: 630626:EBL_RS15835
uniprot id: I2BCT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

630626:EBL RS12790
gene id: 630626:EBL_RS12790
uniprot id: I2BB28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

630626:EBL RS14195
gene id: 630626:EBL_RS14195
uniprot id: I2BBU9
names: Similarity
messages: Belongs to the pirin family.

630626:EBL RS08470
gene id: 630626:EBL_RS08470
uniprot id: I2B8J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS10315
gene id: 630626:EBL_RS10315
uniprot id: I2B9M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

630626:EBL RS12010
gene id: 630626:EBL_RS12010
uniprot id: I2BAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

630626:EBL RS13415
gene id: 630626:EBL_RS13415
uniprot id: I2BBE3
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

630626:EBL RS13810
gene id: 630626:EBL_RS13810
uniprot id: I2BBM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

630626:EBL RS05880
gene id: 630626:EBL_RS05880
uniprot id: I2B726
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS12250
gene id: 630626:EBL_RS12250
uniprot id: I2BAR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

630626:EBL RS12570
gene id: 630626:EBL_RS12570
uniprot id: I2BAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

630626:EBL RS13065
gene id: 630626:EBL_RS13065
uniprot id: I2BB77
names: Similarity
messages: Belongs to the asparagine synthetase family.

630626:EBL RS04240
gene id: 630626:EBL_RS04240
uniprot id: I2B653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS15875
gene id: 630626:EBL_RS15875
uniprot id: I2BCU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

630626:EBL RS19255
gene id: 630626:EBL_RS19255
uniprot id: I2BEP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

630626:EBL RS01795
gene id: 630626:EBL_RS01795
uniprot id: I2B4P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

630626:EBL RS02620
gene id: 630626:EBL_RS02620
uniprot id: I2B568
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

630626:EBL RS13310
gene id: 630626:EBL_RS13310
uniprot id: I2BBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

630626:EBL RS00020
gene id: 630626:EBL_RS00020
uniprot id: I2B3N7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

630626:EBL RS08210
gene id: 630626:EBL_RS08210
uniprot id: I2B8E2
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

630626:EBL RS02865
gene id: 630626:EBL_RS02865
uniprot id: I2B5B8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

630626:EBL RS05235
gene id: 630626:EBL_RS05235
uniprot id: I2B6Q2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

630626:EBL RS09235
gene id: 630626:EBL_RS09235
uniprot id: I2B900
names: Function
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA.

630626:EBL RS03875
gene id: 630626:EBL_RS03875
uniprot id: I2B5X9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

630626:EBL RS12880
gene id: 630626:EBL_RS12880
uniprot id: I2BB40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

630626:EBL RS06210
gene id: 630626:EBL_RS06210
uniprot id: I2B794
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

630626:EBL RS15010
gene id: 630626:EBL_RS15010
uniprot id: I2BCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

630626:EBL RS11210
gene id: 630626:EBL_RS11210
uniprot id: I2BA56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

630626:EBL RS16690
gene id: 630626:EBL_RS16690
uniprot id: I2BD99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

630626:EBL RS15075
gene id: 630626:EBL_RS15075
uniprot id: I2BCD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

630626:EBL RS17765
gene id: 630626:EBL_RS17765
uniprot id: I2BDW6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS03995
gene id: 630626:EBL_RS03995
uniprot id: I2B602
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

630626:EBL RS03320
gene id: 630626:EBL_RS03320
uniprot id: I2B5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

630626:EBL RS03100
gene id: 630626:EBL_RS03100
uniprot id: I2B5G6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

630626:EBL RS00815
gene id: 630626:EBL_RS00815
uniprot id: I2B451
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

630626:EBL RS02660
gene id: 630626:EBL_RS02660
uniprot id: I2B576
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

630626:EBL RS11155
gene id: 630626:EBL_RS11155
uniprot id: I2BA45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

630626:EBL RS05830
gene id: 630626:EBL_RS05830
uniprot id: I2B716
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

630626:EBL RS17465
gene id: 630626:EBL_RS17465
uniprot id: I2BDQ1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

630626:EBL RS02940
gene id: 630626:EBL_RS02940
uniprot id: I2B5D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS00335
gene id: 630626:EBL_RS00335
uniprot id: I2B3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

630626:EBL RS08685
gene id: 630626:EBL_RS08685
uniprot id: I2B8P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Monomer.
messages: Periplasm
messages: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.

630626:EBL RS11875
gene id: 630626:EBL_RS11875
uniprot id: I2BAJ0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06580
gene id: 630626:EBL_RS06580
uniprot id: I2B7G8
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

630626:EBL RS12645
gene id: 630626:EBL_RS12645
uniprot id: I2BAZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

630626:EBL RS12105
gene id: 630626:EBL_RS12105
uniprot id: I2BAN6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

630626:EBL RS19295
gene id: 630626:EBL_RS19295
uniprot id: I2BEQ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS07910
gene id: 630626:EBL_RS07910
uniprot id: I2B880
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

630626:EBL RS05365
gene id: 630626:EBL_RS05365
uniprot id: I2B6S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

630626:EBL RS12700
gene id: 630626:EBL_RS12700
uniprot id: I2BB07
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

630626:EBL RS18720
gene id: 630626:EBL_RS18720
uniprot id: I2BEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

630626:EBL RS15720
gene id: 630626:EBL_RS15720
uniprot id: I2BCQ9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15930
gene id: 630626:EBL_RS15930
uniprot id: I2BCV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).

630626:EBL RS16125
gene id: 630626:EBL_RS16125
uniprot id: I2BCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

630626:EBL RS16295
gene id: 630626:EBL_RS16295
uniprot id: I2BD24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

630626:EBL RS12285
gene id: 630626:EBL_RS12285
uniprot id: I2BAS2
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

630626:EBL RS19380
gene id: 630626:EBL_RS19380
uniprot id: I2BES2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

630626:EBL RS00560
gene id: 630626:EBL_RS00560
uniprot id: I2B400
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

630626:EBL RS13260
gene id: 630626:EBL_RS13260
uniprot id: I2BBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

630626:EBL RS14750
gene id: 630626:EBL_RS14750
uniprot id: I2BC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS18325
gene id: 630626:EBL_RS18325
uniprot id: I2BE68
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

630626:EBL RS19060
gene id: 630626:EBL_RS19060
uniprot id: I2BEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS07570
gene id: 630626:EBL_RS07570
uniprot id: I2B812
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

630626:EBL RS09075
gene id: 630626:EBL_RS09075
uniprot id: I2B8W9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11325
gene id: 630626:EBL_RS11325
uniprot id: I2BA80
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

630626:EBL RS04520
gene id: 630626:EBL_RS04520
uniprot id: I2B6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

630626:EBL RS07175
gene id: 630626:EBL_RS07175
uniprot id: I2B7T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

630626:EBL RS19095
gene id: 630626:EBL_RS19095
uniprot id: I2BEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

630626:EBL RS16550
gene id: 630626:EBL_RS16550
uniprot id: I2BD74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

630626:EBL RS14010
gene id: 630626:EBL_RS14010
uniprot id: I2BBR3
names: Similarity
messages: Belongs to the UPF0234 family.

630626:EBL RS02090
gene id: 630626:EBL_RS02090
uniprot id: I2B4V4
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

630626:EBL RS12600
gene id: 630626:EBL_RS12600
uniprot id: I2BAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

630626:EBL RS15285
gene id: 630626:EBL_RS15285
uniprot id: I2BCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

630626:EBL RS14300
gene id: 630626:EBL_RS14300
uniprot id: I2BBX1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

630626:EBL RS13925
gene id: 630626:EBL_RS13925
uniprot id: I2BBP5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

630626:EBL RS13890
gene id: 630626:EBL_RS13890
uniprot id: I2BBN8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS16410
gene id: 630626:EBL_RS16410
uniprot id: I2BD46
names: Function
names: Similarity
messages: Belongs to the DnaT family.
messages: This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.

630626:EBL RS02255
gene id: 630626:EBL_RS02255
uniprot id: I2B4Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS00485
gene id: 630626:EBL_RS00485
uniprot id: I2B3Y5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11595
gene id: 630626:EBL_RS11595
uniprot id: I2BAD5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

630626:EBL RS12075
gene id: 630626:EBL_RS12075
uniprot id: I2BAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

630626:EBL RS17575
gene id: 630626:EBL_RS17575
uniprot id: I2BDS5
names: Similarity
messages: Belongs to the YjdM family.

630626:EBL RS06740
gene id: 630626:EBL_RS06740
uniprot id: I2B7K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

630626:EBL RS02625
gene id: 630626:EBL_RS02625
uniprot id: I2B569
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS17355
gene id: 630626:EBL_RS17355
uniprot id: I2BDN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

630626:EBL RS15455
gene id: 630626:EBL_RS15455
uniprot id: I2BCK5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

630626:EBL RS04805
gene id: 630626:EBL_RS04805
uniprot id: I2B6G0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS08425
gene id: 630626:EBL_RS08425
uniprot id: I2B8I7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS09680
gene id: 630626:EBL_RS09680
uniprot id: I2B990
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LigB/MhpB extradiol dioxygenase family.
messages: Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
messages: Homotetramer.

630626:EBL RS07710
gene id: 630626:EBL_RS07710
uniprot id: I2B840
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

630626:EBL RS16175
gene id: 630626:EBL_RS16175
uniprot id: I2BD00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

630626:EBL RS11960
gene id: 630626:EBL_RS11960
uniprot id: I2BAK6
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

630626:EBL RS04615
gene id: 630626:EBL_RS04615
uniprot id: I2B6C6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

630626:EBL RS14775
gene id: 630626:EBL_RS14775
uniprot id: I2BC70
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS18625
gene id: 630626:EBL_RS18625
uniprot id: I2BEC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

630626:EBL RS06885
gene id: 630626:EBL_RS06885
uniprot id: I2B7N0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

630626:EBL RS01875
gene id: 630626:EBL_RS01875
uniprot id: I2B4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

630626:EBL RS07715
gene id: 630626:EBL_RS07715
uniprot id: I2B841
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

630626:EBL RS16155
gene id: 630626:EBL_RS16155
uniprot id: I2BCZ6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

630626:EBL RS17065
gene id: 630626:EBL_RS17065
uniprot id: I2BDH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS14870
gene id: 630626:EBL_RS14870
uniprot id: I2BC92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS01665
gene id: 630626:EBL_RS01665
uniprot id: I2B4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

630626:EBL RS08445
gene id: 630626:EBL_RS08445
uniprot id: I2B8J0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

630626:EBL RS00435
gene id: 630626:EBL_RS00435
uniprot id: I2B3X5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

630626:EBL RS10950
gene id: 630626:EBL_RS10950
uniprot id: I2BA06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

630626:EBL RS00395
gene id: 630626:EBL_RS00395
uniprot id: I2B3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
messages: Cell inner membrane
messages: Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).

630626:EBL RS06600
gene id: 630626:EBL_RS06600
uniprot id: I2B7H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

630626:EBL RS15125
gene id: 630626:EBL_RS15125
uniprot id: I2BCE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

630626:EBL RS18490
gene id: 630626:EBL_RS18490
uniprot id: I2BE99
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

630626:EBL RS11285
gene id: 630626:EBL_RS11285
uniprot id: I2BA71
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

630626:EBL RS07660
gene id: 630626:EBL_RS07660
uniprot id: I2B830
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

630626:EBL RS18155
gene id: 630626:EBL_RS18155
uniprot id: I2BE34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

630626:EBL RS17825
gene id: 630626:EBL_RS17825
uniprot id: I2BDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS05100
gene id: 630626:EBL_RS05100
uniprot id: I2B6M3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

630626:EBL RS17720
gene id: 630626:EBL_RS17720
uniprot id: I2BDV7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homotetramer.
messages: Periplasm

630626:EBL RS04540
gene id: 630626:EBL_RS04540
uniprot id: I2B6B1
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS17250
gene id: 630626:EBL_RS17250
uniprot id: I2BDL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

630626:EBL RS17450
gene id: 630626:EBL_RS17450
uniprot id: I2BDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

630626:EBL RS02040
gene id: 630626:EBL_RS02040
uniprot id: I2B4U4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

630626:EBL RS15795
gene id: 630626:EBL_RS15795
uniprot id: I2BCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

630626:EBL RS15840
gene id: 630626:EBL_RS15840
uniprot id: I2BCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

630626:EBL RS14205
gene id: 630626:EBL_RS14205
uniprot id: I2BBV1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

630626:EBL RS05480
gene id: 630626:EBL_RS05480
uniprot id: I2B6U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

630626:EBL RS10305
gene id: 630626:EBL_RS10305
uniprot id: I2B9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

630626:EBL RS06765
gene id: 630626:EBL_RS06765
uniprot id: I2B7K5
names: Similarity
messages: Belongs to the peptidase A24 family.

630626:EBL RS13845
gene id: 630626:EBL_RS13845
uniprot id: I2BBM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS20110
gene id: 630626:EBL_RS20110
uniprot id: I2BC31
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

630626:EBL RS13910
gene id: 630626:EBL_RS13910
uniprot id: I2BBP2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

630626:EBL RS18850
gene id: 630626:EBL_RS18850
uniprot id: I2BEG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS08635
gene id: 630626:EBL_RS08635
uniprot id: I2B8M9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

630626:EBL RS09880
gene id: 630626:EBL_RS09880
uniprot id: I2B9D3
names: Similarity
messages: Belongs to the peptidase C40 family.

630626:EBL RS03235
gene id: 630626:EBL_RS03235
uniprot id: I2B5J5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

630626:EBL RS13895
gene id: 630626:EBL_RS13895
uniprot id: I2BBN9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS07275
gene id: 630626:EBL_RS07275
uniprot id: I2B7V7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS01815
gene id: 630626:EBL_RS01815
uniprot id: I2B4Q0
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

630626:EBL RS09625
gene id: 630626:EBL_RS09625
uniprot id: I2B979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS17280
gene id: 630626:EBL_RS17280
uniprot id: I2BDL7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

630626:EBL RS06245
gene id: 630626:EBL_RS06245
uniprot id: I2B7A2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

630626:EBL RS18780
gene id: 630626:EBL_RS18780
uniprot id: I2BEF2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS08230
gene id: 630626:EBL_RS08230
uniprot id: I2B8E7
names: Subcellular Location Annotation
messages: target cell cytoplasm

630626:EBL RS02555
gene id: 630626:EBL_RS02555
uniprot id: I2B553
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

630626:EBL RS09245
gene id: 630626:EBL_RS09245
uniprot id: I2B902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS00890
gene id: 630626:EBL_RS00890
uniprot id: I2B466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

630626:EBL RS13760
gene id: 630626:EBL_RS13760
uniprot id: I2BBL0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

630626:EBL RS09215
gene id: 630626:EBL_RS09215
uniprot id: I2B8Z5
names: Similarity
messages: Belongs to the UPF0263 family.

630626:EBL RS06250
gene id: 630626:EBL_RS06250
uniprot id: I2B7A3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

630626:EBL RS16770
gene id: 630626:EBL_RS16770
uniprot id: I2BDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

630626:EBL RS03300
gene id: 630626:EBL_RS03300
uniprot id: I2B5K8
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

630626:EBL RS01345
gene id: 630626:EBL_RS01345
uniprot id: I2B4G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

630626:EBL RS15575
gene id: 630626:EBL_RS15575
uniprot id: I2BCM9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

630626:EBL RS16195
gene id: 630626:EBL_RS16195
uniprot id: I2BD04
names: Similarity
messages: Belongs to the threonine synthase family.

630626:EBL RS02675
gene id: 630626:EBL_RS02675
uniprot id: I2B579
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

630626:EBL RS10320
gene id: 630626:EBL_RS10320
uniprot id: I2B9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

630626:EBL RS00900
gene id: 630626:EBL_RS00900
uniprot id: I2B468
names: Similarity
messages: Belongs to the leucine-binding protein family.

630626:EBL RS00750
gene id: 630626:EBL_RS00750
uniprot id: I2B437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Membrane

630626:EBL RS08355
gene id: 630626:EBL_RS08355
uniprot id: I2B8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS13025
gene id: 630626:EBL_RS13025
uniprot id: I2BB69
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

630626:EBL RS01685
gene id: 630626:EBL_RS01685
uniprot id: I2B4M3
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).

630626:EBL RS09150
gene id: 630626:EBL_RS09150
uniprot id: I2B8Y2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

630626:EBL RS12095
gene id: 630626:EBL_RS12095
uniprot id: I2BAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

630626:EBL RS01010
gene id: 630626:EBL_RS01010
uniprot id: I2B491
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

630626:EBL RS14270
gene id: 630626:EBL_RS14270
uniprot id: I2BBW5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

630626:EBL RS00990
gene id: 630626:EBL_RS00990
uniprot id: I2B487
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

630626:EBL RS18545
gene id: 630626:EBL_RS18545
uniprot id: I2BEA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS00250
gene id: 630626:EBL_RS00250
uniprot id: I2B3T8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

630626:EBL RS04990
gene id: 630626:EBL_RS04990
uniprot id: I2B6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

630626:EBL RS09180
gene id: 630626:EBL_RS09180
uniprot id: I2B8Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS05440
gene id: 630626:EBL_RS05440
uniprot id: I2B6T8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

630626:EBL RS03630
gene id: 630626:EBL_RS03630
uniprot id: I2B5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS01970
gene id: 630626:EBL_RS01970
uniprot id: I2B4T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS08845
gene id: 630626:EBL_RS08845
uniprot id: I2B8S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

630626:EBL RS15235
gene id: 630626:EBL_RS15235
uniprot id: I2BCG6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

630626:EBL RS04740
gene id: 630626:EBL_RS04740
uniprot id: I2B6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

630626:EBL RS09675
gene id: 630626:EBL_RS09675
uniprot id: I2B989
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MhpC family.
messages: Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.
messages: Homodimer.

630626:EBL RS17905
gene id: 630626:EBL_RS17905
uniprot id: I2BDZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

630626:EBL RS08025
gene id: 630626:EBL_RS08025
uniprot id: I2B8A3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

630626:EBL RS17980
gene id: 630626:EBL_RS17980
uniprot id: I2BE06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

630626:EBL RS12735
gene id: 630626:EBL_RS12735
uniprot id: I2BB17
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

630626:EBL RS01715
gene id: 630626:EBL_RS01715
uniprot id: I2B4M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

630626:EBL RS13540
gene id: 630626:EBL_RS13540
uniprot id: I2BBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

630626:EBL RS06865
gene id: 630626:EBL_RS06865
uniprot id: I2B7M6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

630626:EBL RS06125
gene id: 630626:EBL_RS06125
uniprot id: I2B776
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS12885
gene id: 630626:EBL_RS12885
uniprot id: I2BB41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

630626:EBL RS11840
gene id: 630626:EBL_RS11840
uniprot id: I2BAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

630626:EBL RS16075
gene id: 630626:EBL_RS16075
uniprot id: I2BCY0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

630626:EBL RS07820
gene id: 630626:EBL_RS07820
uniprot id: I2B862
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

630626:EBL RS09750
gene id: 630626:EBL_RS09750
uniprot id: I2B9A5
names: Similarity
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.

630626:EBL RS10330
gene id: 630626:EBL_RS10330
uniprot id: I2B9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

630626:EBL RS02735
gene id: 630626:EBL_RS02735
uniprot id: I2B591
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

630626:EBL RS08655
gene id: 630626:EBL_RS08655
uniprot id: I2B8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

630626:EBL RS09610
gene id: 630626:EBL_RS09610
uniprot id: I2B975
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

630626:EBL RS09660
gene id: 630626:EBL_RS09660
uniprot id: I2B986
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
messages: Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
messages: Interacts with MhpF.

630626:EBL RS08630
gene id: 630626:EBL_RS08630
uniprot id: I2B8M8
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

630626:EBL RS09195
gene id: 630626:EBL_RS09195
uniprot id: I2B8Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

630626:EBL RS01945
gene id: 630626:EBL_RS01945
uniprot id: I2B4S6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

630626:EBL RS03725
gene id: 630626:EBL_RS03725
uniprot id: I2B5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

630626:EBL RS18375
gene id: 630626:EBL_RS18375
uniprot id: I2BE75
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

630626:EBL RS04930
gene id: 630626:EBL_RS04930
uniprot id: I2B6I8
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

630626:EBL RS10390
gene id: 630626:EBL_RS10390
uniprot id: I2B9P2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS10935
gene id: 630626:EBL_RS10935
uniprot id: I2BA03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

630626:EBL RS04005
gene id: 630626:EBL_RS04005
uniprot id: I2B604
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

630626:EBL RS06665
gene id: 630626:EBL_RS06665
uniprot id: I2B7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS10725
gene id: 630626:EBL_RS10725
uniprot id: I2B9V9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS11340
gene id: 630626:EBL_RS11340
uniprot id: I2BA83
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

630626:EBL RS11090
gene id: 630626:EBL_RS11090
uniprot id: I2BA34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS18485
gene id: 630626:EBL_RS18485
uniprot id: I2BE98
names: Similarity
messages: Belongs to the UPF0438 family.

630626:EBL RS13250
gene id: 630626:EBL_RS13250
uniprot id: I2BBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

630626:EBL RS05185
gene id: 630626:EBL_RS05185
uniprot id: I2B6P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

630626:EBL RS02880
gene id: 630626:EBL_RS02880
uniprot id: I2B5C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

630626:EBL RS03520
gene id: 630626:EBL_RS03520
uniprot id: I2B5Q6
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

630626:EBL RS05815
gene id: 630626:EBL_RS05815
uniprot id: I2B713
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

630626:EBL RS06200
gene id: 630626:EBL_RS06200
uniprot id: I2B792
names: Similarity
messages: Belongs to the CinA family.

630626:EBL RS12910
gene id: 630626:EBL_RS12910
uniprot id: I2BB46
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

630626:EBL RS20130
gene id: 630626:EBL_RS20130
uniprot id: I2BCF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

630626:EBL RS14050
gene id: 630626:EBL_RS14050
uniprot id: I2BBS1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

630626:EBL RS09385
gene id: 630626:EBL_RS09385
uniprot id: I2B931
names: Similarity
messages: Belongs to the group II decarboxylase family.

630626:EBL RS15750
gene id: 630626:EBL_RS15750
uniprot id: I2BCR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

630626:EBL RS12435
gene id: 630626:EBL_RS12435
uniprot id: I2BAV3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

630626:EBL RS02270
gene id: 630626:EBL_RS02270
uniprot id: I2B4Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

630626:EBL RS06470
gene id: 630626:EBL_RS06470
uniprot id: I2B7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

630626:EBL RS11640
gene id: 630626:EBL_RS11640
uniprot id: I2BAE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

630626:EBL RS11965
gene id: 630626:EBL_RS11965
uniprot id: I2BAK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

630626:EBL RS00800
gene id: 630626:EBL_RS00800
uniprot id: I2B448
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

630626:EBL RS02960
gene id: 630626:EBL_RS02960
uniprot id: I2B5D7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

630626:EBL RS11560
gene id: 630626:EBL_RS11560
uniprot id: I2BAC8
names: Similarity
messages: Belongs to the UPF0227 family.

630626:EBL RS16250
gene id: 630626:EBL_RS16250
uniprot id: I2BD15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

630626:EBL RS18550
gene id: 630626:EBL_RS18550
uniprot id: I2BEA5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

630626:EBL RS02615
gene id: 630626:EBL_RS02615
uniprot id: I2B567
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

630626:EBL RS15425
gene id: 630626:EBL_RS15425
uniprot id: I2BCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

630626:EBL RS13280
gene id: 630626:EBL_RS13280
uniprot id: I2BBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell inner membrane

630626:EBL RS18090
gene id: 630626:EBL_RS18090
uniprot id: I2BE25
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

630626:EBL RS07655
gene id: 630626:EBL_RS07655
uniprot id: I2B829
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

630626:EBL RS02755
gene id: 630626:EBL_RS02755
uniprot id: I2B595
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

630626:EBL RS17240
gene id: 630626:EBL_RS17240
uniprot id: I2BDK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

630626:EBL RS18810
gene id: 630626:EBL_RS18810
uniprot id: I2BEF8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

630626:EBL RS09835
gene id: 630626:EBL_RS09835
uniprot id: I2B9C3
names: Similarity
messages: Belongs to the FrmR/RcnR family.

630626:EBL RS02360
gene id: 630626:EBL_RS02360
uniprot id: I2B515
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

630626:EBL RS20015
gene id: 630626:EBL_RS20015
uniprot id: I2BAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

630626:EBL RS07335
gene id: 630626:EBL_RS07335
uniprot id: I2B7W9
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

630626:EBL RS18445
gene id: 630626:EBL_RS18445
uniprot id: I2BE89
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS05380
gene id: 630626:EBL_RS05380
uniprot id: I2B6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

630626:EBL RS09670
gene id: 630626:EBL_RS09670
uniprot id: I2B988
names: Function
names: Similarity
messages: Belongs to the hydratase/decarboxylase family. MhpD subfamily.
messages: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.

630626:EBL RS11700
gene id: 630626:EBL_RS11700
uniprot id: I2BAF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Belongs to the RNase E/G family. RNase G subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

630626:EBL RS14805
gene id: 630626:EBL_RS14805
uniprot id: I2BC79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

630626:EBL RS07085
gene id: 630626:EBL_RS07085
uniprot id: I2B7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

630626:EBL RS18170
gene id: 630626:EBL_RS18170
uniprot id: I2BE37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

630626:EBL RS06375
gene id: 630626:EBL_RS06375
uniprot id: I2B7C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

630626:EBL RS06310
gene id: 630626:EBL_RS06310
uniprot id: I2B7B5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

630626:EBL RS12235
gene id: 630626:EBL_RS12235
uniprot id: I2BAR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

630626:EBL RS19020
gene id: 630626:EBL_RS19020
uniprot id: I2BEK1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

630626:EBL RS18000
gene id: 630626:EBL_RS18000
uniprot id: I2BE10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

630626:EBL RS01305
gene id: 630626:EBL_RS01305
uniprot id: I2B4F4
names: Similarity
messages: Belongs to the DsrF/TusC family.

630626:EBL RS16140
gene id: 630626:EBL_RS16140
uniprot id: I2BCZ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

630626:EBL RS13975
gene id: 630626:EBL_RS13975
uniprot id: I2BBQ6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15400
gene id: 630626:EBL_RS15400
uniprot id: I2BCJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

630626:EBL RS06235
gene id: 630626:EBL_RS06235
uniprot id: I2B7A0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS06555
gene id: 630626:EBL_RS06555
uniprot id: I2B7G3
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15180
gene id: 630626:EBL_RS15180
uniprot id: I2BCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgC/AgfC family.
messages: Periplasm

630626:EBL RS15505
gene id: 630626:EBL_RS15505
uniprot id: I2BCL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

630626:EBL RS11750
gene id: 630626:EBL_RS11750
uniprot id: I2BAG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

630626:EBL RS02920
gene id: 630626:EBL_RS02920
uniprot id: I2B5C9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

630626:EBL RS07760
gene id: 630626:EBL_RS07760
uniprot id: I2B850
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS02780
gene id: 630626:EBL_RS02780
uniprot id: I2B5A1
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

630626:EBL RS07350
gene id: 630626:EBL_RS07350
uniprot id: I2B7X1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS09225
gene id: 630626:EBL_RS09225
uniprot id: I2B8Z8
names: Similarity
messages: Belongs to the YciI family.

630626:EBL RS07955
gene id: 630626:EBL_RS07955
uniprot id: I2B889
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS19235
gene id: 630626:EBL_RS19235
uniprot id: I2BEP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

630626:EBL RS13010
gene id: 630626:EBL_RS13010
uniprot id: I2BB66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS17435
gene id: 630626:EBL_RS17435
uniprot id: I2BDP5
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

630626:EBL RS12450
gene id: 630626:EBL_RS12450
uniprot id: I2BAV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

630626:EBL RS00125
gene id: 630626:EBL_RS00125
uniprot id: I2B3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

630626:EBL RS10980
gene id: 630626:EBL_RS10980
uniprot id: I2BA12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

630626:EBL RS03565
gene id: 630626:EBL_RS03565
uniprot id: I2B5R5
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-1104 that is involved in catalysis.

630626:EBL RS01435
gene id: 630626:EBL_RS01435
uniprot id: I2B4H9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

630626:EBL RS18800
gene id: 630626:EBL_RS18800
uniprot id: I2BEF6
names: Subcellular Location Annotation
messages: Cell inner membrane

630626:EBL RS05780
gene id: 630626:EBL_RS05780
uniprot id: I2B707
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

630626:EBL RS03750
gene id: 630626:EBL_RS03750
uniprot id: I2B5V2
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15645
gene id: 630626:EBL_RS15645
uniprot id: I2BCP3
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

630626:EBL RS15390
gene id: 630626:EBL_RS15390
uniprot id: I2BCJ2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

630626:EBL RS11495
gene id: 630626:EBL_RS11495
uniprot id: I2BAB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS17395
gene id: 630626:EBL_RS17395
uniprot id: I2BDN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

630626:EBL RS07585
gene id: 630626:EBL_RS07585
uniprot id: I2B815
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

630626:EBL RS13200
gene id: 630626:EBL_RS13200
uniprot id: I2BB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

630626:EBL RS15160
gene id: 630626:EBL_RS15160
uniprot id: I2BCF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

630626:EBL RS04125
gene id: 630626:EBL_RS04125
uniprot id: I2B629
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

630626:EBL RS03835
gene id: 630626:EBL_RS03835
uniprot id: I2B5X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

630626:EBL RS02845
gene id: 630626:EBL_RS02845
uniprot id: I2B5B4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

630626:EBL RS16245
gene id: 630626:EBL_RS16245
uniprot id: I2BD14
names: Similarity
messages: Belongs to the transglycosylase Slt family.

630626:EBL RS16105
gene id: 630626:EBL_RS16105
uniprot id: I2BCY6
names: Similarity
messages: Belongs to the IlvD/Edd family.

630626:EBL RS06160
gene id: 630626:EBL_RS06160
uniprot id: I2B783
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

630626:EBL RS17775
gene id: 630626:EBL_RS17775
uniprot id: I2BDW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS01370
gene id: 630626:EBL_RS01370
uniprot id: I2B4G6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

630626:EBL RS19185
gene id: 630626:EBL_RS19185
uniprot id: I2BEN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

630626:EBL RS00465
gene id: 630626:EBL_RS00465
uniprot id: I2B3Y1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

630626:EBL RS12745
gene id: 630626:EBL_RS12745
uniprot id: I2BB19
names: Similarity
messages: Belongs to the ModE family.

630626:EBL RS12205
gene id: 630626:EBL_RS12205
uniprot id: I2BAQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

630626:EBL RS10770
gene id: 630626:EBL_RS10770
uniprot id: I2B9W8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

630626:EBL RS17220
gene id: 630626:EBL_RS17220
uniprot id: I2BDK5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS08105
gene id: 630626:EBL_RS08105
uniprot id: I2B8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

630626:EBL RS01810
gene id: 630626:EBL_RS01810
uniprot id: I2B4P9
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

630626:EBL RS01675
gene id: 630626:EBL_RS01675
uniprot id: I2B4M1
names: Similarity
messages: Belongs to the RNase E/G family. RNase G subfamily.

630626:EBL RS16035
gene id: 630626:EBL_RS16035
uniprot id: I2BCX2
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11865
gene id: 630626:EBL_RS11865
uniprot id: I2BAI8
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

630626:EBL RS08175
gene id: 630626:EBL_RS08175
uniprot id: I2B8D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell inner membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS19220
gene id: 630626:EBL_RS19220
uniprot id: I2BEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

630626:EBL RS07435
gene id: 630626:EBL_RS07435
uniprot id: I2B7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

630626:EBL RS02945
gene id: 630626:EBL_RS02945
uniprot id: I2B5D4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

630626:EBL RS18050
gene id: 630626:EBL_RS18050
uniprot id: I2BE20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

630626:EBL RS07665
gene id: 630626:EBL_RS07665
uniprot id: I2B831
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

630626:EBL RS17640
gene id: 630626:EBL_RS17640
uniprot id: I2BDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

630626:EBL RS06805
gene id: 630626:EBL_RS06805
uniprot id: I2B7L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane

630626:EBL RS13815
gene id: 630626:EBL_RS13815
uniprot id: I2BBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS00960
gene id: 630626:EBL_RS00960
uniprot id: I2B481
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

630626:EBL RS08485
gene id: 630626:EBL_RS08485
uniprot id: I2B8J8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

630626:EBL RS06485
gene id: 630626:EBL_RS06485
uniprot id: I2B7E9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS00230
gene id: 630626:EBL_RS00230
uniprot id: I2B3T3
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS12005
gene id: 630626:EBL_RS12005
uniprot id: I2BAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

630626:EBL RS10945
gene id: 630626:EBL_RS10945
uniprot id: I2BA05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

630626:EBL RS04970
gene id: 630626:EBL_RS04970
uniprot id: I2B6J6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RodZ family.
messages: Cell inner membrane
messages: Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
messages: The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.

630626:EBL RS02575
gene id: 630626:EBL_RS02575
uniprot id: I2B558
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

630626:EBL RS01210
gene id: 630626:EBL_RS01210
uniprot id: I2B4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS05915
gene id: 630626:EBL_RS05915
uniprot id: I2B733
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS02995
gene id: 630626:EBL_RS02995
uniprot id: I2B5E4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

630626:EBL RS12495
gene id: 630626:EBL_RS12495
uniprot id: I2BAW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

630626:EBL RS11735
gene id: 630626:EBL_RS11735
uniprot id: I2BAG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

630626:EBL RS05955
gene id: 630626:EBL_RS05955
uniprot id: I2B741
names: Subunit
messages: Homooctamer.

630626:EBL RS05965
gene id: 630626:EBL_RS05965
uniprot id: I2B743
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

630626:EBL RS09125
gene id: 630626:EBL_RS09125
uniprot id: I2B8X9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS04605
gene id: 630626:EBL_RS04605
uniprot id: I2B6C4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

630626:EBL RS10745
gene id: 630626:EBL_RS10745
uniprot id: I2B9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Forms a complex with MdtJ.
messages: Membrane

630626:EBL RS11945
gene id: 630626:EBL_RS11945
uniprot id: I2BAK3
names: Subcellular Location Annotation
messages: Cell inner membrane

630626:EBL RS14745
gene id: 630626:EBL_RS14745
uniprot id: I2BC64
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS18760
gene id: 630626:EBL_RS18760
uniprot id: I2BEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS01935
gene id: 630626:EBL_RS01935
uniprot id: I2B4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

630626:EBL RS15360
gene id: 630626:EBL_RS15360
uniprot id: I2BCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

630626:EBL RS17620
gene id: 630626:EBL_RS17620
uniprot id: I2BDT4
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11635
gene id: 630626:EBL_RS11635
uniprot id: I2BAE3
names: Similarity
messages: Belongs to the fabD family.

630626:EBL RS04580
gene id: 630626:EBL_RS04580
uniprot id: I2B6B9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the N-terminal section; belongs to the CdiA toxin family.
messages: target cell cytoplasm

630626:EBL RS13155
gene id: 630626:EBL_RS13155
uniprot id: I2BB87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS05925
gene id: 630626:EBL_RS05925
uniprot id: I2B735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

630626:EBL RS18015
gene id: 630626:EBL_RS18015
uniprot id: I2BE13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

630626:EBL RS11825
gene id: 630626:EBL_RS11825
uniprot id: I2BAI0
names: Similarity
messages: Belongs to the PhoH family.

630626:EBL RS02280
gene id: 630626:EBL_RS02280
uniprot id: I2B4Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
messages: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal. Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homodimer.

630626:EBL RS01475
gene id: 630626:EBL_RS01475
uniprot id: I2B4I8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

630626:EBL RS01495
gene id: 630626:EBL_RS01495
uniprot id: I2B4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

630626:EBL RS09410
gene id: 630626:EBL_RS09410
uniprot id: I2B937
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

630626:EBL RS16090
gene id: 630626:EBL_RS16090
uniprot id: I2BCY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

630626:EBL RS12890
gene id: 630626:EBL_RS12890
uniprot id: I2BB42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

630626:EBL RS06640
gene id: 630626:EBL_RS06640
uniprot id: I2B7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

630626:EBL RS04165
gene id: 630626:EBL_RS04165
uniprot id: I2B637
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

630626:EBL RS08115
gene id: 630626:EBL_RS08115
uniprot id: I2B8C2
names: Similarity
messages: Belongs to the pyruvate kinase family.

630626:EBL RS01955
gene id: 630626:EBL_RS01955
uniprot id: I2B4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

630626:EBL RS16160
gene id: 630626:EBL_RS16160
uniprot id: I2BCZ7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

630626:EBL RS04025
gene id: 630626:EBL_RS04025
uniprot id: I2B608
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

630626:EBL RS18990
gene id: 630626:EBL_RS18990
uniprot id: I2BEJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

630626:EBL RS00650
gene id: 630626:EBL_RS00650
uniprot id: I2B418
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS00910
gene id: 630626:EBL_RS00910
uniprot id: I2B471
names: Similarity
messages: Belongs to the leucine-binding protein family.

630626:EBL RS19325
gene id: 630626:EBL_RS19325
uniprot id: I2BER0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

630626:EBL RS12380
gene id: 630626:EBL_RS12380
uniprot id: I2BAU1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

630626:EBL RS18995
gene id: 630626:EBL_RS18995
uniprot id: I2BEJ6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

630626:EBL RS18300
gene id: 630626:EBL_RS18300
uniprot id: I2BE63
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

630626:EBL RS14330
gene id: 630626:EBL_RS14330
uniprot id: I2BBX8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

630626:EBL RS12110
gene id: 630626:EBL_RS12110
uniprot id: I2BAN7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS05415
gene id: 630626:EBL_RS05415
uniprot id: I2B6T2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

630626:EBL RS10395
gene id: 630626:EBL_RS10395
uniprot id: I2B9P3
names: Similarity
messages: Belongs to the pirin family.

630626:EBL RS00720
gene id: 630626:EBL_RS00720
uniprot id: I2B431
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

630626:EBL RS06625
gene id: 630626:EBL_RS06625
uniprot id: I2B7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS09740
gene id: 630626:EBL_RS09740
uniprot id: I2B9A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS11205
gene id: 630626:EBL_RS11205
uniprot id: I2BA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

630626:EBL RS01995
gene id: 630626:EBL_RS01995
uniprot id: I2B4T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS15300
gene id: 630626:EBL_RS15300
uniprot id: I2BCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

630626:EBL RS18175
gene id: 630626:EBL_RS18175
uniprot id: I2BE38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

630626:EBL RS13330
gene id: 630626:EBL_RS13330
uniprot id: I2BBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS06755
gene id: 630626:EBL_RS06755
uniprot id: I2B7K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

630626:EBL RS17785
gene id: 630626:EBL_RS17785
uniprot id: I2BDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

630626:EBL RS01820
gene id: 630626:EBL_RS01820
uniprot id: I2B4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

630626:EBL RS01625
gene id: 630626:EBL_RS01625
uniprot id: I2B4L1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

630626:EBL RS00255
gene id: 630626:EBL_RS00255
uniprot id: I2B3T9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

630626:EBL RS05895
gene id: 630626:EBL_RS05895
uniprot id: I2B729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS20155
gene id: 630626:EBL_RS20155
uniprot id: I2BD33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

630626:EBL RS11505
gene id: 630626:EBL_RS11505
uniprot id: I2BAB7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-92 and Arg-95) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

630626:EBL RS15955
gene id: 630626:EBL_RS15955
uniprot id: I2BCV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

630626:EBL RS16210
gene id: 630626:EBL_RS16210
uniprot id: I2BD07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS17245
gene id: 630626:EBL_RS17245
uniprot id: I2BDL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

630626:EBL RS10820
gene id: 630626:EBL_RS10820
uniprot id: I2B9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tus family.
messages: Cytoplasm
messages: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

630626:EBL RS11900
gene id: 630626:EBL_RS11900
uniprot id: I2BAJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

630626:EBL RS01325
gene id: 630626:EBL_RS01325
uniprot id: I2B4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

630626:EBL RS16130
gene id: 630626:EBL_RS16130
uniprot id: I2BCZ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

630626:EBL RS16980
gene id: 630626:EBL_RS16980
uniprot id: I2BDF6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

630626:EBL RS14165
gene id: 630626:EBL_RS14165
uniprot id: I2BBU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

630626:EBL RS01735
gene id: 630626:EBL_RS01735
uniprot id: I2B4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

630626:EBL RS01355
gene id: 630626:EBL_RS01355
uniprot id: I2B4G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

630626:EBL RS05165
gene id: 630626:EBL_RS05165
uniprot id: I2B6N7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS00105
gene id: 630626:EBL_RS00105
uniprot id: I2B3Q4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS06040
gene id: 630626:EBL_RS06040
uniprot id: I2B758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS14155
gene id: 630626:EBL_RS14155
uniprot id: I2BBU2
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

630626:EBL RS14925
gene id: 630626:EBL_RS14925
uniprot id: I2BCA3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS18180
gene id: 630626:EBL_RS18180
uniprot id: I2BE39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

630626:EBL RS18730
gene id: 630626:EBL_RS18730
uniprot id: I2BEE2
names: Similarity
messages: Belongs to the FBPase class 2 family.

630626:EBL RS04630
gene id: 630626:EBL_RS04630
uniprot id: I2B6C9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

630626:EBL RS12185
gene id: 630626:EBL_RS12185
uniprot id: I2BAQ2
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

630626:EBL RS19030
gene id: 630626:EBL_RS19030
uniprot id: I2BEK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

630626:EBL RS09060
gene id: 630626:EBL_RS09060
uniprot id: I2B8W6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

630626:EBL RS07885
gene id: 630626:EBL_RS07885
uniprot id: I2B875
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS17600
gene id: 630626:EBL_RS17600
uniprot id: I2BDT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS11630
gene id: 630626:EBL_RS11630
uniprot id: I2BAE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

630626:EBL RS13150
gene id: 630626:EBL_RS13150
uniprot id: I2BB86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

630626:EBL RS08740
gene id: 630626:EBL_RS08740
uniprot id: I2B8Q1
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

630626:EBL RS14060
gene id: 630626:EBL_RS14060
uniprot id: I2BBS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

630626:EBL RS08515
gene id: 630626:EBL_RS08515
uniprot id: I2B8K5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS01655
gene id: 630626:EBL_RS01655
uniprot id: I2B4L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

630626:EBL RS13395
gene id: 630626:EBL_RS13395
uniprot id: I2BBD9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

630626:EBL RS18775
gene id: 630626:EBL_RS18775
uniprot id: I2BEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

630626:EBL RS18380
gene id: 630626:EBL_RS18380
uniprot id: I2BE76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.

630626:EBL RS06045
gene id: 630626:EBL_RS06045
uniprot id: I2B759
names: Similarity
messages: Belongs to the UPF0304 family.

630626:EBL RS02045
gene id: 630626:EBL_RS02045
uniprot id: I2B4U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

630626:EBL RS04845
gene id: 630626:EBL_RS04845
uniprot id: I2B6H0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS04270
gene id: 630626:EBL_RS04270
uniprot id: I2B659
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

630626:EBL RS02085
gene id: 630626:EBL_RS02085
uniprot id: I2B4V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

630626:EBL RS03150
gene id: 630626:EBL_RS03150
uniprot id: I2B5H6
names: Similarity
messages: Belongs to the CitG/MdcB family.

630626:EBL RS18415
gene id: 630626:EBL_RS18415
uniprot id: I2BE83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

630626:EBL RS08865
gene id: 630626:EBL_RS08865
uniprot id: I2B8S6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

630626:EBL RS19065
gene id: 630626:EBL_RS19065
uniprot id: I2BEL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

630626:EBL RS10815
gene id: 630626:EBL_RS10815
uniprot id: I2B9X8
names: Subcellular Location Annotation
messages: Cell inner membrane

630626:EBL RS17780
gene id: 630626:EBL_RS17780
uniprot id: I2BDW9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

630626:EBL RS16205
gene id: 630626:EBL_RS16205
uniprot id: I2BD06
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

630626:EBL RS04375
gene id: 630626:EBL_RS04375
uniprot id: I2B676
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

630626:EBL RS07545
gene id: 630626:EBL_RS07545
uniprot id: I2B806
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

630626:EBL RS14035
gene id: 630626:EBL_RS14035
uniprot id: I2BBR8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

630626:EBL RS06120
gene id: 630626:EBL_RS06120
uniprot id: I2B775
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS12190
gene id: 630626:EBL_RS12190
uniprot id: I2BAQ3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

630626:EBL RS16685
gene id: 630626:EBL_RS16685
uniprot id: I2BD98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

630626:EBL RS14240
gene id: 630626:EBL_RS14240
uniprot id: I2BBV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

630626:EBL RS12325
gene id: 630626:EBL_RS12325
uniprot id: I2BAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS18655
gene id: 630626:EBL_RS18655
uniprot id: I2BEC6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

630626:EBL RS00950
gene id: 630626:EBL_RS00950
uniprot id: I2B479
names: Similarity
messages: Belongs to the pirin family.

630626:EBL RS00055
gene id: 630626:EBL_RS00055
uniprot id: I2B3P4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

630626:EBL RS13600
gene id: 630626:EBL_RS13600
uniprot id: I2BBH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

630626:EBL RS10365
gene id: 630626:EBL_RS10365
uniprot id: I2B9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

630626:EBL RS15155
gene id: 630626:EBL_RS15155
uniprot id: I2BCF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

630626:EBL RS17330
gene id: 630626:EBL_RS17330
uniprot id: I2BDM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

630626:EBL RS04395
gene id: 630626:EBL_RS04395
uniprot id: I2B682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

630626:EBL RS17345
gene id: 630626:EBL_RS17345
uniprot id: I2BDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

630626:EBL RS01290
gene id: 630626:EBL_RS01290
uniprot id: I2B4F1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

630626:EBL RS12060
gene id: 630626:EBL_RS12060
uniprot id: I2BAM7
names: Similarity
messages: Belongs to the YkuD family.

630626:EBL RS04910
gene id: 630626:EBL_RS04910
uniprot id: I2B6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

630626:EBL RS11605
gene id: 630626:EBL_RS11605
uniprot id: I2BAD7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

630626:EBL RS01470
gene id: 630626:EBL_RS01470
uniprot id: I2B4I7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

630626:EBL RS07565
gene id: 630626:EBL_RS07565
uniprot id: I2B811
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

630626:EBL RS16495
gene id: 630626:EBL_RS16495
uniprot id: I2BD63
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS00565
gene id: 630626:EBL_RS00565
uniprot id: I2B401
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

630626:EBL RS16555
gene id: 630626:EBL_RS16555
uniprot id: I2BD75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

630626:EBL RS11335
gene id: 630626:EBL_RS11335
uniprot id: I2BA82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

630626:EBL RS01890
gene id: 630626:EBL_RS01890
uniprot id: I2B4R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

630626:EBL RS00670
gene id: 630626:EBL_RS00670
uniprot id: I2B422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

630626:EBL RS01440
gene id: 630626:EBL_RS01440
uniprot id: I2B4I0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

630626:EBL RS18135
gene id: 630626:EBL_RS18135
uniprot id: I2BE30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

630626:EBL RS14955
gene id: 630626:EBL_RS14955
uniprot id: I2BCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell inner membrane

630626:EBL RS18825
gene id: 630626:EBL_RS18825
uniprot id: I2BEG1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

630626:EBL RS05835
gene id: 630626:EBL_RS05835
uniprot id: I2B717
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

630626:EBL RS18130
gene id: 630626:EBL_RS18130
uniprot id: I2BE29
names: Similarity
messages: Belongs to the IMPACT family.

630626:EBL RS02300
gene id: 630626:EBL_RS02300
uniprot id: I2B4Z7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS06450
gene id: 630626:EBL_RS06450
uniprot id: I2B7E2
names: Similarity
messages: Belongs to the elongation factor P family.

630626:EBL RS14790
gene id: 630626:EBL_RS14790
uniprot id: I2BC73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L2HGDH family.
messages: Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Cell inner membrane

630626:EBL RS08785
gene id: 630626:EBL_RS08785
uniprot id: I2B8R0
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

630626:EBL RS15445
gene id: 630626:EBL_RS15445
uniprot id: I2BCK3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS05990
gene id: 630626:EBL_RS05990
uniprot id: I2B748
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS17880
gene id: 630626:EBL_RS17880
uniprot id: I2BDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

630626:EBL RS01660
gene id: 630626:EBL_RS01660
uniprot id: I2B4L8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

630626:EBL RS15540
gene id: 630626:EBL_RS15540
uniprot id: I2BCM2
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

630626:EBL RS02535
gene id: 630626:EBL_RS02535
uniprot id: I2B550
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

630626:EBL RS13135
gene id: 630626:EBL_RS13135
uniprot id: I2BB83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS05940
gene id: 630626:EBL_RS05940
uniprot id: I2B738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

630626:EBL RS14675
gene id: 630626:EBL_RS14675
uniprot id: I2BC50
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

630626:EBL RS06935
gene id: 630626:EBL_RS06935
uniprot id: I2B7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

630626:EBL RS09165
gene id: 630626:EBL_RS09165
uniprot id: I2B8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

630626:EBL RS13770
gene id: 630626:EBL_RS13770
uniprot id: I2BBL2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

630626:EBL RS09440
gene id: 630626:EBL_RS09440
uniprot id: I2B943
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
messages: Catalyzes the proton-dependent transport of sialic acid.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08825
gene id: 630626:EBL_RS08825
uniprot id: I2B8R8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS11000
gene id: 630626:EBL_RS11000
uniprot id: I2BA16
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

630626:EBL RS17895
gene id: 630626:EBL_RS17895
uniprot id: I2BDZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS02515
gene id: 630626:EBL_RS02515
uniprot id: I2B546
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS02210
gene id: 630626:EBL_RS02210
uniprot id: I2B4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08545
gene id: 630626:EBL_RS08545
uniprot id: I2B8L1
names: Similarity
messages: Belongs to the UPF0181 family.

630626:EBL RS00665
gene id: 630626:EBL_RS00665
uniprot id: I2B421
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

630626:EBL RS01725
gene id: 630626:EBL_RS01725
uniprot id: I2B4N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

630626:EBL RS04755
gene id: 630626:EBL_RS04755
uniprot id: I2B6F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

630626:EBL RS13460
gene id: 630626:EBL_RS13460
uniprot id: I2BBF1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

630626:EBL RS17100
gene id: 630626:EBL_RS17100
uniprot id: I2BDI1
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

630626:EBL RS18315
gene id: 630626:EBL_RS18315
uniprot id: I2BE66
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

630626:EBL RS04510
gene id: 630626:EBL_RS04510
uniprot id: I2B6A5
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

630626:EBL RS03820
gene id: 630626:EBL_RS03820
uniprot id: I2B5W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

630626:EBL RS07780
gene id: 630626:EBL_RS07780
uniprot id: I2B854
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

630626:EBL RS17470
gene id: 630626:EBL_RS17470
uniprot id: I2BDQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

630626:EBL RS03680
gene id: 630626:EBL_RS03680
uniprot id: I2B5T8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

630626:EBL RS10970
gene id: 630626:EBL_RS10970
uniprot id: I2BA10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

630626:EBL RS18785
gene id: 630626:EBL_RS18785
uniprot id: I2BEF3
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS16585
gene id: 630626:EBL_RS16585
uniprot id: I2BD81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS08475
gene id: 630626:EBL_RS08475
uniprot id: I2B8J6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06960
gene id: 630626:EBL_RS06960
uniprot id: I2B7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS05920
gene id: 630626:EBL_RS05920
uniprot id: I2B734
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS10895
gene id: 630626:EBL_RS10895
uniprot id: I2B9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

630626:EBL RS05115
gene id: 630626:EBL_RS05115
uniprot id: I2B6M7
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS00430
gene id: 630626:EBL_RS00430
uniprot id: I2B3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

630626:EBL RS10755
gene id: 630626:EBL_RS10755
uniprot id: I2B9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

630626:EBL RS00175
gene id: 630626:EBL_RS00175
uniprot id: I2B3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

630626:EBL RS07395
gene id: 630626:EBL_RS07395
uniprot id: I2B7X8
names: Similarity
messages: Belongs to the Vsr family.

630626:EBL RS11500
gene id: 630626:EBL_RS11500
uniprot id: I2BAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

630626:EBL RS04030
gene id: 630626:EBL_RS04030
uniprot id: I2B609
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

630626:EBL RS16355
gene id: 630626:EBL_RS16355
uniprot id: I2BD37
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

630626:EBL RS15080
gene id: 630626:EBL_RS15080
uniprot id: I2BCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

630626:EBL RS10595
gene id: 630626:EBL_RS10595
uniprot id: I2B9T5
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

630626:EBL RS06975
gene id: 630626:EBL_RS06975
uniprot id: I2B7P8
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

630626:EBL RS17225
gene id: 630626:EBL_RS17225
uniprot id: I2BDK6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

630626:EBL RS04175
gene id: 630626:EBL_RS04175
uniprot id: I2B639
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

630626:EBL RS12525
gene id: 630626:EBL_RS12525
uniprot id: I2BAX1
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

630626:EBL RS07115
gene id: 630626:EBL_RS07115
uniprot id: I2B7S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS17130
gene id: 630626:EBL_RS17130
uniprot id: I2BDI7
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

630626:EBL RS01445
gene id: 630626:EBL_RS01445
uniprot id: I2B4I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

630626:EBL RS06605
gene id: 630626:EBL_RS06605
uniprot id: I2B7H3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

630626:EBL RS02610
gene id: 630626:EBL_RS02610
uniprot id: I2B566
names: Function
names: Similarity
messages: Belongs to the GlgS family.
messages: Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.

630626:EBL RS17350
gene id: 630626:EBL_RS17350
uniprot id: I2BDN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS14680
gene id: 630626:EBL_RS14680
uniprot id: I2BC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

630626:EBL RS18450
gene id: 630626:EBL_RS18450
uniprot id: I2BE90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS17770
gene id: 630626:EBL_RS17770
uniprot id: I2BDW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

630626:EBL RS02240
gene id: 630626:EBL_RS02240
uniprot id: I2B4Y4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

630626:EBL RS18350
gene id: 630626:EBL_RS18350
uniprot id: I2BE70
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS16675
gene id: 630626:EBL_RS16675
uniprot id: I2BD96
names: Similarity
messages: Belongs to the peptidase C69 family.

630626:EBL RS10905
gene id: 630626:EBL_RS10905
uniprot id: I2B9Z7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS05095
gene id: 630626:EBL_RS05095
uniprot id: I2B6M2
names: Similarity
messages: Belongs to the ArsC family.

630626:EBL RS00765
gene id: 630626:EBL_RS00765
uniprot id: I2B440
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS12120
gene id: 630626:EBL_RS12120
uniprot id: I2BAN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

630626:EBL RS14695
gene id: 630626:EBL_RS14695
uniprot id: I2BC54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

630626:EBL RS04160
gene id: 630626:EBL_RS04160
uniprot id: I2B636
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

630626:EBL RS01425
gene id: 630626:EBL_RS01425
uniprot id: I2B4H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

630626:EBL RS08560
gene id: 630626:EBL_RS08560
uniprot id: I2B8L4
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

630626:EBL RS03795
gene id: 630626:EBL_RS03795
uniprot id: I2B5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

630626:EBL RS12540
gene id: 630626:EBL_RS12540
uniprot id: I2BAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.
messages: Cell outer membrane

630626:EBL RS05120
gene id: 630626:EBL_RS05120
uniprot id: I2B6M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

630626:EBL RS15325
gene id: 630626:EBL_RS15325
uniprot id: I2BCH9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

630626:EBL RS02640
gene id: 630626:EBL_RS02640
uniprot id: I2B572
names: Similarity
messages: Belongs to the UPF0441 family.

630626:EBL RS04450
gene id: 630626:EBL_RS04450
uniprot id: I2B692
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06345
gene id: 630626:EBL_RS06345
uniprot id: I2B7C2
names: Function
names: Similarity
messages: Belongs to the class-C beta-lactamase family.
messages: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

630626:EBL RS13180
gene id: 630626:EBL_RS13180
uniprot id: I2BB92
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

630626:EBL RS13205
gene id: 630626:EBL_RS13205
uniprot id: I2BB97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

630626:EBL RS02930
gene id: 630626:EBL_RS02930
uniprot id: I2B5D1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

630626:EBL RS04975
gene id: 630626:EBL_RS04975
uniprot id: I2B6J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

630626:EBL RS01885
gene id: 630626:EBL_RS01885
uniprot id: I2B4R4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

630626:EBL RS07860
gene id: 630626:EBL_RS07860
uniprot id: I2B870
names: Similarity
messages: Belongs to the SUI1 family.

630626:EBL RS19260
gene id: 630626:EBL_RS19260
uniprot id: I2BEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

630626:EBL RS00005
gene id: 630626:EBL_RS00005
uniprot id: I2B3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

630626:EBL RS18240
gene id: 630626:EBL_RS18240
uniprot id: I2BE51
names: Similarity
messages: Belongs to the Rht family.

630626:EBL RS09685
gene id: 630626:EBL_RS09685
uniprot id: I2B991
names: Function
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.
messages: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).

630626:EBL RS07255
gene id: 630626:EBL_RS07255
uniprot id: I2B7V3
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

630626:EBL RS17310
gene id: 630626:EBL_RS17310
uniprot id: I2BDM3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

630626:EBL RS16985
gene id: 630626:EBL_RS16985
uniprot id: I2BDF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Heterododecamer (2C3:3R2) of six catalytic PyrB chains organized as two trimers (C3), and six regulatory PyrI chains organized as three dimers (R2).
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

630626:EBL RS04760
gene id: 630626:EBL_RS04760
uniprot id: I2B6F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

630626:EBL RS01465
gene id: 630626:EBL_RS01465
uniprot id: I2B4I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

630626:EBL RS16230
gene id: 630626:EBL_RS16230
uniprot id: I2BD11
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.

630626:EBL RS04940
gene id: 630626:EBL_RS04940
uniprot id: I2B6J0
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

630626:EBL RS12875
gene id: 630626:EBL_RS12875
uniprot id: I2BB39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS03220
gene id: 630626:EBL_RS03220
uniprot id: I2B5J2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

630626:EBL RS01320
gene id: 630626:EBL_RS01320
uniprot id: I2B4F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

630626:EBL RS02690
gene id: 630626:EBL_RS02690
uniprot id: I2B582
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

630626:EBL RS03880
gene id: 630626:EBL_RS03880
uniprot id: I2B5Y0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

630626:EBL RS04710
gene id: 630626:EBL_RS04710
uniprot id: I2B6E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

630626:EBL RS16530
gene id: 630626:EBL_RS16530
uniprot id: I2BD70
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS15725
gene id: 630626:EBL_RS15725
uniprot id: I2BCR0
names: Similarity
messages: Belongs to the GSP E family.

630626:EBL RS16165
gene id: 630626:EBL_RS16165
uniprot id: I2BCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

630626:EBL RS02260
gene id: 630626:EBL_RS02260
uniprot id: I2B4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Has been proposed to be a redox modulator.
messages: Membrane

630626:EBL RS11830
gene id: 630626:EBL_RS11830
uniprot id: I2BAI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

630626:EBL RS03990
gene id: 630626:EBL_RS03990
uniprot id: I2B601
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS13145
gene id: 630626:EBL_RS13145
uniprot id: I2BB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

630626:EBL RS02855
gene id: 630626:EBL_RS02855
uniprot id: I2B5B6
names: Similarity
messages: Belongs to the TPP enzyme family.

630626:EBL RS03140
gene id: 630626:EBL_RS03140
uniprot id: I2B5H4
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS07140
gene id: 630626:EBL_RS07140
uniprot id: I2B7T0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

630626:EBL RS12140
gene id: 630626:EBL_RS12140
uniprot id: I2BAP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS01000
gene id: 630626:EBL_RS01000
uniprot id: I2B489
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

630626:EBL RS00145
gene id: 630626:EBL_RS00145
uniprot id: I2B3R3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

630626:EBL RS05075
gene id: 630626:EBL_RS05075
uniprot id: I2B6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

630626:EBL RS12870
gene id: 630626:EBL_RS12870
uniprot id: I2BB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

630626:EBL RS11555
gene id: 630626:EBL_RS11555
uniprot id: I2BAC7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

630626:EBL RS01100
gene id: 630626:EBL_RS01100
uniprot id: I2B4B0
names: Similarity
messages: Belongs to the HSP15 family.

630626:EBL RS08420
gene id: 630626:EBL_RS08420
uniprot id: I2B8I6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS11235
gene id: 630626:EBL_RS11235
uniprot id: I2BA61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS12680
gene id: 630626:EBL_RS12680
uniprot id: I2BB03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

630626:EBL RS02465
gene id: 630626:EBL_RS02465
uniprot id: I2B535
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

630626:EBL RS01500
gene id: 630626:EBL_RS01500
uniprot id: I2B4J3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS06930
gene id: 630626:EBL_RS06930
uniprot id: I2B7N9
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

630626:EBL RS06955
gene id: 630626:EBL_RS06955
uniprot id: I2B7P4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

630626:EBL RS11050
gene id: 630626:EBL_RS11050
uniprot id: I2BA26
names: Similarity
messages: Belongs to the glyoxalase I family.

630626:EBL RS07855
gene id: 630626:EBL_RS07855
uniprot id: I2B869
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

630626:EBL RS12970
gene id: 630626:EBL_RS12970
uniprot id: I2BB58
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS09240
gene id: 630626:EBL_RS09240
uniprot id: I2B901
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

630626:EBL RS09045
gene id: 630626:EBL_RS09045
uniprot id: I2B8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

630626:EBL RS11165
gene id: 630626:EBL_RS11165
uniprot id: I2BA47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

630626:EBL RS07835
gene id: 630626:EBL_RS07835
uniprot id: I2B865
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

630626:EBL RS07745
gene id: 630626:EBL_RS07745
uniprot id: I2B847
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

630626:EBL RS03780
gene id: 630626:EBL_RS03780
uniprot id: I2B5V8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS01175
gene id: 630626:EBL_RS01175
uniprot id: I2B4C5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

630626:EBL RS14850
gene id: 630626:EBL_RS14850
uniprot id: I2BC88
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

630626:EBL RS16285
gene id: 630626:EBL_RS16285
uniprot id: I2BD22
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

630626:EBL RS03115
gene id: 630626:EBL_RS03115
uniprot id: I2B5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane
messages: Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system).

630626:EBL RS08490
gene id: 630626:EBL_RS08490
uniprot id: I2B8K0
names: Similarity
messages: Belongs to the UPF0053 family.

630626:EBL RS13210
gene id: 630626:EBL_RS13210
uniprot id: I2BB98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

630626:EBL RS17695
gene id: 630626:EBL_RS17695
uniprot id: I2BDV0
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

630626:EBL RS04040
gene id: 630626:EBL_RS04040
uniprot id: I2B611
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS15965
gene id: 630626:EBL_RS15965
uniprot id: I2BCV8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

630626:EBL RS16020
gene id: 630626:EBL_RS16020
uniprot id: I2BCW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of FixA and FixB.
messages: Required for anaerobic carnitine reduction. May bring reductant to CaiA.

630626:EBL RS10360
gene id: 630626:EBL_RS10360
uniprot id: I2B9N6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

630626:EBL RS00905
gene id: 630626:EBL_RS00905
uniprot id: I2B469
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

630626:EBL RS07050
gene id: 630626:EBL_RS07050
uniprot id: I2B7R2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

630626:EBL RS11535
gene id: 630626:EBL_RS11535
uniprot id: I2BAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

630626:EBL RS18540
gene id: 630626:EBL_RS18540
uniprot id: I2BEA2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

630626:EBL RS18630
gene id: 630626:EBL_RS18630
uniprot id: I2BEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS04365
gene id: 630626:EBL_RS04365
uniprot id: I2B674
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

630626:EBL RS02010
gene id: 630626:EBL_RS02010
uniprot id: I2B4T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

630626:EBL RS09035
gene id: 630626:EBL_RS09035
uniprot id: I2B8W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

630626:EBL RS03525
gene id: 630626:EBL_RS03525
uniprot id: I2B5Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS15165
gene id: 630626:EBL_RS15165
uniprot id: I2BCF2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

630626:EBL RS01830
gene id: 630626:EBL_RS01830
uniprot id: I2B4Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

630626:EBL RS16280
gene id: 630626:EBL_RS16280
uniprot id: I2BD21
names: Similarity
messages: Belongs to the Smp family.

630626:EBL RS17200
gene id: 630626:EBL_RS17200
uniprot id: I2BDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

630626:EBL RS06275
gene id: 630626:EBL_RS06275
uniprot id: I2B7A8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated by RcsC.

630626:EBL RS18710
gene id: 630626:EBL_RS18710
uniprot id: I2BED8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

630626:EBL RS13215
gene id: 630626:EBL_RS13215
uniprot id: I2BB99
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

630626:EBL RS01180
gene id: 630626:EBL_RS01180
uniprot id: I2B4C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

630626:EBL RS11485
gene id: 630626:EBL_RS11485
uniprot id: I2BAB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

630626:EBL RS06545
gene id: 630626:EBL_RS06545
uniprot id: I2B7G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS02225
gene id: 630626:EBL_RS02225
uniprot id: I2B4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08605
gene id: 630626:EBL_RS08605
uniprot id: I2B8M3
names: Similarity
messages: Belongs to the UPF0260 family.

630626:EBL RS15435
gene id: 630626:EBL_RS15435
uniprot id: I2BCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

630626:EBL RS18430
gene id: 630626:EBL_RS18430
uniprot id: I2BE86
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

630626:EBL RS00150
gene id: 630626:EBL_RS00150
uniprot id: I2B3R4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

630626:EBL RS14290
gene id: 630626:EBL_RS14290
uniprot id: I2BBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS03160
gene id: 630626:EBL_RS03160
uniprot id: I2B5I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

630626:EBL RS06340
gene id: 630626:EBL_RS06340
uniprot id: I2B7C1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

630626:EBL RS15430
gene id: 630626:EBL_RS15430
uniprot id: I2BCK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

630626:EBL RS16400
gene id: 630626:EBL_RS16400
uniprot id: I2BD44
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

630626:EBL RS15740
gene id: 630626:EBL_RS15740
uniprot id: I2BCR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

630626:EBL RS04905
gene id: 630626:EBL_RS04905
uniprot id: I2B6I3
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

630626:EBL RS12195
gene id: 630626:EBL_RS12195
uniprot id: I2BAQ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS12675
gene id: 630626:EBL_RS12675
uniprot id: I2BB02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

630626:EBL RS06335
gene id: 630626:EBL_RS06335
uniprot id: I2B7C0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

630626:EBL RS17430
gene id: 630626:EBL_RS17430
uniprot id: I2BDP4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

630626:EBL RS01060
gene id: 630626:EBL_RS01060
uniprot id: I2B4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

630626:EBL RS15230
gene id: 630626:EBL_RS15230
uniprot id: I2BCG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

630626:EBL RS05525
gene id: 630626:EBL_RS05525
uniprot id: I2B6V4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

630626:EBL RS09540
gene id: 630626:EBL_RS09540
uniprot id: I2B963
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

630626:EBL RS18920
gene id: 630626:EBL_RS18920
uniprot id: I2BEI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

630626:EBL RS11250
gene id: 630626:EBL_RS11250
uniprot id: I2BA64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

630626:EBL RS07045
gene id: 630626:EBL_RS07045
uniprot id: I2B7R1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

630626:EBL RS06395
gene id: 630626:EBL_RS06395
uniprot id: I2B7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS04610
gene id: 630626:EBL_RS04610
uniprot id: I2B6C5
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS10255
gene id: 630626:EBL_RS10255
uniprot id: I2B9L5
names: Similarity
messages: Belongs to the citrate synthase family.

630626:EBL RS12965
gene id: 630626:EBL_RS12965
uniprot id: I2BB57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

630626:EBL RS01255
gene id: 630626:EBL_RS01255
uniprot id: I2B4E4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

630626:EBL RS00065
gene id: 630626:EBL_RS00065
uniprot id: I2B3P6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS01330
gene id: 630626:EBL_RS01330
uniprot id: I2BE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

630626:EBL RS02585
gene id: 630626:EBL_RS02585
uniprot id: I2B560
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

630626:EBL RS02235
gene id: 630626:EBL_RS02235
uniprot id: I2B4Y3
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS17935
gene id: 630626:EBL_RS17935
uniprot id: I2BDZ7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

630626:EBL RS01850
gene id: 630626:EBL_RS01850
uniprot id: I2B4Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

630626:EBL RS18695
gene id: 630626:EBL_RS18695
uniprot id: I2BED5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

630626:EBL RS18815
gene id: 630626:EBL_RS18815
uniprot id: I2BEF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

630626:EBL RS01415
gene id: 630626:EBL_RS01415
uniprot id: I2B4H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

630626:EBL RS05275
gene id: 630626:EBL_RS05275
uniprot id: I2B6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

630626:EBL RS07785
gene id: 630626:EBL_RS07785
uniprot id: I2B855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

630626:EBL RS16395
gene id: 630626:EBL_RS16395
uniprot id: I2BD42
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS17095
gene id: 630626:EBL_RS17095
uniprot id: I2BDI0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

630626:EBL RS06590
gene id: 630626:EBL_RS06590
uniprot id: I2B7H0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS01670
gene id: 630626:EBL_RS01670
uniprot id: I2B4M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

630626:EBL RS12475
gene id: 630626:EBL_RS12475
uniprot id: I2BAW1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

630626:EBL RS12350
gene id: 630626:EBL_RS12350
uniprot id: I2BAT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS12040
gene id: 630626:EBL_RS12040
uniprot id: I2BAM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS16115
gene id: 630626:EBL_RS16115
uniprot id: I2BCY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

630626:EBL RS18040
gene id: 630626:EBL_RS18040
uniprot id: I2BE18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

630626:EBL RS01280
gene id: 630626:EBL_RS01280
uniprot id: I2B4E9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

630626:EBL RS17405
gene id: 630626:EBL_RS17405
uniprot id: I2BDN9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

630626:EBL RS17475
gene id: 630626:EBL_RS17475
uniprot id: I2BDQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

630626:EBL RS00555
gene id: 630626:EBL_RS00555
uniprot id: I2B3Z9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS03265
gene id: 630626:EBL_RS03265
uniprot id: I2B5K1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Catalyzes the phosphorylation of D-allose to D-allose 6-phosphate.

630626:EBL RS05375
gene id: 630626:EBL_RS05375
uniprot id: I2B6S5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

630626:EBL RS06735
gene id: 630626:EBL_RS06735
uniprot id: I2B7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

630626:EBL RS00985
gene id: 630626:EBL_RS00985
uniprot id: I2B486
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by fructose-1,6-bisphosphate (F16BP) and inhibited by AMP.
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS15240
gene id: 630626:EBL_RS15240
uniprot id: I2BCG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0294 family.
messages: Cytoplasm

630626:EBL RS00290
gene id: 630626:EBL_RS00290
uniprot id: I2B3U6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

630626:EBL RS19200
gene id: 630626:EBL_RS19200
uniprot id: I2BEN4
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS00515
gene id: 630626:EBL_RS00515
uniprot id: I2B3Z1
names: Similarity
messages: Belongs to the peptidase A31 family.

630626:EBL RS07810
gene id: 630626:EBL_RS07810
uniprot id: I2B860
names: Similarity
messages: Belongs to the peptidase S49 family.

630626:EBL RS18195
gene id: 630626:EBL_RS18195
uniprot id: I2BE42
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

630626:EBL RS06190
gene id: 630626:EBL_RS06190
uniprot id: I2B789
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

630626:EBL RS03490
gene id: 630626:EBL_RS03490
uniprot id: I2B5Q0
names: Similarity
messages: Belongs to the UPF0303 family.

630626:EBL RS01430
gene id: 630626:EBL_RS01430
uniprot id: I2B4H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

630626:EBL RS18245
gene id: 630626:EBL_RS18245
uniprot id: I2BE52
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

630626:EBL RS10750
gene id: 630626:EBL_RS10750
uniprot id: I2B9W4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

630626:EBL RS16150
gene id: 630626:EBL_RS16150
uniprot id: I2BCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

630626:EBL RS14740
gene id: 630626:EBL_RS14740
uniprot id: I2BC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS02730
gene id: 630626:EBL_RS02730
uniprot id: I2B590
names: Similarity
messages: Belongs to the GSP E family.

630626:EBL RS03555
gene id: 630626:EBL_RS03555
uniprot id: I2B5R3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

630626:EBL RS15800
gene id: 630626:EBL_RS15800
uniprot id: I2BCS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

630626:EBL RS01230
gene id: 630626:EBL_RS01230
uniprot id: I2B4D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

630626:EBL RS05025
gene id: 630626:EBL_RS05025
uniprot id: I2B6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

630626:EBL RS01880
gene id: 630626:EBL_RS01880
uniprot id: I2B4R3
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

630626:EBL RS06785
gene id: 630626:EBL_RS06785
uniprot id: I2B7K9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS03970
gene id: 630626:EBL_RS03970
uniprot id: I2B5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

630626:EBL RS16360
gene id: 630626:EBL_RS16360
uniprot id: I2BD38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

630626:EBL RS19585
gene id: 630626:EBL_RS19585
uniprot id: I2B555
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

630626:EBL RS12155
gene id: 630626:EBL_RS12155
uniprot id: I2BAP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS06035
gene id: 630626:EBL_RS06035
uniprot id: I2B757
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

630626:EBL RS07190
gene id: 630626:EBL_RS07190
uniprot id: I2B7U0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

630626:EBL RS14110
gene id: 630626:EBL_RS14110
uniprot id: I2BBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

630626:EBL RS05330
gene id: 630626:EBL_RS05330
uniprot id: I2B6R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

630626:EBL RS04145
gene id: 630626:EBL_RS04145
uniprot id: I2B633
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

630626:EBL RS15485
gene id: 630626:EBL_RS15485
uniprot id: I2BCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

630626:EBL RS15490
gene id: 630626:EBL_RS15490
uniprot id: I2BCL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

630626:EBL RS15520
gene id: 630626:EBL_RS15520
uniprot id: I2BCL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS07485
gene id: 630626:EBL_RS07485
uniprot id: I2B7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

630626:EBL RS03825
gene id: 630626:EBL_RS03825
uniprot id: I2B5W9
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

630626:EBL RS07695
gene id: 630626:EBL_RS07695
uniprot id: I2B837
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

630626:EBL RS18860
gene id: 630626:EBL_RS18860
uniprot id: I2BEG8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

630626:EBL RS04045
gene id: 630626:EBL_RS04045
uniprot id: I2B612
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

630626:EBL RS06710
gene id: 630626:EBL_RS06710
uniprot id: I2B7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

630626:EBL RS08340
gene id: 630626:EBL_RS08340
uniprot id: I2B8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS11795
gene id: 630626:EBL_RS11795
uniprot id: I2BAH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YmdB family.
messages: Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
messages: Homodimer. Interacts with RNase III.

630626:EBL RS00160
gene id: 630626:EBL_RS00160
uniprot id: I2B3R6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

630626:EBL RS06365
gene id: 630626:EBL_RS06365
uniprot id: I2B7C5
names: Similarity
messages: To H.influenzae HI_0842.

630626:EBL RS18035
gene id: 630626:EBL_RS18035
uniprot id: I2BE17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.
messages: Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA.

630626:EBL RS16970
gene id: 630626:EBL_RS16970
uniprot id: I2BDF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS04965
gene id: 630626:EBL_RS04965
uniprot id: I2B6J5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

630626:EBL RS03135
gene id: 630626:EBL_RS03135
uniprot id: I2B5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

630626:EBL RS00450
gene id: 630626:EBL_RS00450
uniprot id: I2B3X8
names: Similarity
messages: Belongs to the HypE family.

630626:EBL RS08580
gene id: 630626:EBL_RS08580
uniprot id: I2B8L8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

630626:EBL RS11460
gene id: 630626:EBL_RS11460
uniprot id: I2BAA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

630626:EBL RS12020
gene id: 630626:EBL_RS12020
uniprot id: I2BAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

630626:EBL RS18755
gene id: 630626:EBL_RS18755
uniprot id: I2BEE7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS12420
gene id: 630626:EBL_RS12420
uniprot id: I2BAV0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS06090
gene id: 630626:EBL_RS06090
uniprot id: I2B769
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

630626:EBL RS13740
gene id: 630626:EBL_RS13740
uniprot id: I2BBK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

630626:EBL RS03275
gene id: 630626:EBL_RS03275
uniprot id: I2B5K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

630626:EBL RS16340
gene id: 630626:EBL_RS16340
uniprot id: I2BD34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

630626:EBL RS12635
gene id: 630626:EBL_RS12635
uniprot id: I2BAZ3
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

630626:EBL RS03910
gene id: 630626:EBL_RS03910
uniprot id: I2B5Y3
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

630626:EBL RS00860
gene id: 630626:EBL_RS00860
uniprot id: I2B460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

630626:EBL RS17940
gene id: 630626:EBL_RS17940
uniprot id: I2BDZ8
names: Similarity
messages: Belongs to the GARS family.

630626:EBL RS01455
gene id: 630626:EBL_RS01455
uniprot id: I2B4I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

630626:EBL RS04020
gene id: 630626:EBL_RS04020
uniprot id: I2B607
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS01640
gene id: 630626:EBL_RS01640
uniprot id: I2B4L4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

630626:EBL RS05005
gene id: 630626:EBL_RS05005
uniprot id: I2B6K3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

630626:EBL RS03005
gene id: 630626:EBL_RS03005
uniprot id: I2B5E6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

630626:EBL RS02650
gene id: 630626:EBL_RS02650
uniprot id: I2B574
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

630626:EBL RS17645
gene id: 630626:EBL_RS17645
uniprot id: I2BDT9
names: Similarity
messages: Belongs to the GST superfamily.

630626:EBL RS18670
gene id: 630626:EBL_RS18670
uniprot id: I2BED0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

630626:EBL RS08035
gene id: 630626:EBL_RS08035
uniprot id: I2B8A5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

630626:EBL RS07410
gene id: 630626:EBL_RS07410
uniprot id: I2B7Y2
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.

630626:EBL RS02470
gene id: 630626:EBL_RS02470
uniprot id: I2B536
names: Function
messages: Required for maximal bacterial cellulose synthesis.

630626:EBL RS17140
gene id: 630626:EBL_RS17140
uniprot id: I2BDI9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS00265
gene id: 630626:EBL_RS00265
uniprot id: I2B3U1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

630626:EBL RS05445
gene id: 630626:EBL_RS05445
uniprot id: I2B6T9
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

630626:EBL RS16860
gene id: 630626:EBL_RS16860
uniprot id: I2BDD2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

630626:EBL RS18280
gene id: 630626:EBL_RS18280
uniprot id: I2BE59
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

630626:EBL RS01020
gene id: 630626:EBL_RS01020
uniprot id: I2B493
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

630626:EBL RS02365
gene id: 630626:EBL_RS02365
uniprot id: I2B516
names: Similarity
messages: Belongs to the phosphohexose mutase family.

630626:EBL RS19275
gene id: 630626:EBL_RS19275
uniprot id: I2BEP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

630626:EBL RS04535
gene id: 630626:EBL_RS04535
uniprot id: I2B6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

630626:EBL RS01035
gene id: 630626:EBL_RS01035
uniprot id: I2B496
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

630626:EBL RS14715
gene id: 630626:EBL_RS14715
uniprot id: I2BC58
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

630626:EBL RS16290
gene id: 630626:EBL_RS16290
uniprot id: I2BD23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

630626:EBL RS04935
gene id: 630626:EBL_RS04935
uniprot id: I2B6I9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

630626:EBL RS14440
gene id: 630626:EBL_RS14440
uniprot id: I2BC01
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

630626:EBL RS12000
gene id: 630626:EBL_RS12000
uniprot id: I2BAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

630626:EBL RS01385
gene id: 630626:EBL_RS01385
uniprot id: I2B4G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

630626:EBL RS08955
gene id: 630626:EBL_RS08955
uniprot id: I2B8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

630626:EBL RS04265
gene id: 630626:EBL_RS04265
uniprot id: I2B658
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

630626:EBL RS10975
gene id: 630626:EBL_RS10975
uniprot id: I2BA11
names: Similarity
messages: Belongs to the GST superfamily.

630626:EBL RS02765
gene id: 630626:EBL_RS02765
uniprot id: I2B598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS04525
gene id: 630626:EBL_RS04525
uniprot id: I2B6A8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

630626:EBL RS06510
gene id: 630626:EBL_RS06510
uniprot id: I2B7F4
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

630626:EBL RS13565
gene id: 630626:EBL_RS13565
uniprot id: I2BBH2
names: Similarity
messages: To H.influenzae HI_0842.

630626:EBL RS00795
gene id: 630626:EBL_RS00795
uniprot id: I2B447
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

630626:EBL RS09495
gene id: 630626:EBL_RS09495
uniprot id: I2B954
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

630626:EBL RS01075
gene id: 630626:EBL_RS01075
uniprot id: I2B4A5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

630626:EBL RS00920
gene id: 630626:EBL_RS00920
uniprot id: I2B473
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS09535
gene id: 630626:EBL_RS09535
uniprot id: I2B962
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

630626:EBL RS18085
gene id: 630626:EBL_RS18085
uniprot id: I2BE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

630626:EBL RS05300
gene id: 630626:EBL_RS05300
uniprot id: I2B6R5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS02175
gene id: 630626:EBL_RS02175
uniprot id: I2B4X1
names: Similarity
messages: Belongs to the pirin family.

630626:EBL RS11565
gene id: 630626:EBL_RS11565
uniprot id: I2BAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

630626:EBL RS07790
gene id: 630626:EBL_RS07790
uniprot id: I2B856
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

630626:EBL RS09055
gene id: 630626:EBL_RS09055
uniprot id: I2B8W5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

630626:EBL RS01765
gene id: 630626:EBL_RS01765
uniprot id: I2B4N9
names: Similarity
messages: Belongs to the glutamate synthase family.

630626:EBL RS10220
gene id: 630626:EBL_RS10220
uniprot id: I2B9K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

630626:EBL RS06820
gene id: 630626:EBL_RS06820
uniprot id: I2B7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS10875
gene id: 630626:EBL_RS10875
uniprot id: I2B9Z0
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS06725
gene id: 630626:EBL_RS06725
uniprot id: I2B7J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS18360
gene id: 630626:EBL_RS18360
uniprot id: I2BE72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

630626:EBL RS09340
gene id: 630626:EBL_RS09340
uniprot id: I2B922
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

630626:EBL RS20235
gene id: 630626:EBL_RS20235
uniprot id: I2BET7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

630626:EBL RS08745
gene id: 630626:EBL_RS08745
uniprot id: I2B8Q2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

630626:EBL RS10285
gene id: 630626:EBL_RS10285
uniprot id: I2B9M1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

630626:EBL RS08325
gene id: 630626:EBL_RS08325
uniprot id: I2B8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

630626:EBL RS01045
gene id: 630626:EBL_RS01045
uniprot id: I2B498
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

630626:EBL RS01705
gene id: 630626:EBL_RS01705
uniprot id: I2B4M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell inner membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS14095
gene id: 630626:EBL_RS14095
uniprot id: I2BBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

630626:EBL RS19050
gene id: 630626:EBL_RS19050
uniprot id: I2BEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08415
gene id: 630626:EBL_RS08415
uniprot id: I2B8I5
names: Similarity
messages: Belongs to the peptidase S41A family.

630626:EBL RS16200
gene id: 630626:EBL_RS16200
uniprot id: I2BD05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

630626:EBL RS13410
gene id: 630626:EBL_RS13410
uniprot id: I2BBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GppA/Ppx family.
messages: Cell membrane
messages: Membrane

630626:EBL RS05175
gene id: 630626:EBL_RS05175
uniprot id: I2B6P0
names: Subunit
messages: Homodimer.

630626:EBL RS16735
gene id: 630626:EBL_RS16735
uniprot id: I2BDA8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15920
gene id: 630626:EBL_RS15920
uniprot id: I2BCU9
names: Similarity
messages: Belongs to the ribulokinase family.

630626:EBL RS01460
gene id: 630626:EBL_RS01460
uniprot id: I2B4I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

630626:EBL RS09100
gene id: 630626:EBL_RS09100
uniprot id: I2B8X4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS11780
gene id: 630626:EBL_RS11780
uniprot id: I2BAH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

630626:EBL RS19280
gene id: 630626:EBL_RS19280
uniprot id: I2BEQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

630626:EBL RS18405
gene id: 630626:EBL_RS18405
uniprot id: I2BE81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

630626:EBL RS00880
gene id: 630626:EBL_RS00880
uniprot id: I2B464
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

630626:EBL RS16895
gene id: 630626:EBL_RS16895
uniprot id: I2BDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

630626:EBL RS12240
gene id: 630626:EBL_RS12240
uniprot id: I2BAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

630626:EBL RS07825
gene id: 630626:EBL_RS07825
uniprot id: I2B863
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS08510
gene id: 630626:EBL_RS08510
uniprot id: I2B8K4
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

630626:EBL RS04735
gene id: 630626:EBL_RS04735
uniprot id: I2B6E6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

630626:EBL RS01645
gene id: 630626:EBL_RS01645
uniprot id: I2B4L5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

630626:EBL RS00715
gene id: 630626:EBL_RS00715
uniprot id: I2B430
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

630626:EBL RS19005
gene id: 630626:EBL_RS19005
uniprot id: I2BEJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

630626:EBL RS12220
gene id: 630626:EBL_RS12220
uniprot id: I2BAQ9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

630626:EBL RS02915
gene id: 630626:EBL_RS02915
uniprot id: I2B5C8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

630626:EBL RS18480
gene id: 630626:EBL_RS18480
uniprot id: I2BE97
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

630626:EBL RS01960
gene id: 630626:EBL_RS01960
uniprot id: I2B4S9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

630626:EBL RS07170
gene id: 630626:EBL_RS07170
uniprot id: I2B7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

630626:EBL RS16235
gene id: 630626:EBL_RS16235
uniprot id: I2BD12
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

630626:EBL RS07765
gene id: 630626:EBL_RS07765
uniprot id: I2B851
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

630626:EBL RS08020
gene id: 630626:EBL_RS08020
uniprot id: I2B8A2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

630626:EBL RS02770
gene id: 630626:EBL_RS02770
uniprot id: I2B599
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

630626:EBL RS08550
gene id: 630626:EBL_RS08550
uniprot id: I2B8L2
names: Similarity
messages: Belongs to the RutC family.

630626:EBL RS02490
gene id: 630626:EBL_RS02490
uniprot id: I2B540
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

630626:EBL RS08660
gene id: 630626:EBL_RS08660
uniprot id: I2B8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

630626:EBL RS03760
gene id: 630626:EBL_RS03760
uniprot id: I2B5V4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

630626:EBL RS16040
gene id: 630626:EBL_RS16040
uniprot id: I2BCX3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

630626:EBL RS15590
gene id: 630626:EBL_RS15590
uniprot id: I2BCN2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

630626:EBL RS13885
gene id: 630626:EBL_RS13885
uniprot id: I2BBN7
names: Similarity
messages: Belongs to the P(II) protein family.

630626:EBL RS02710
gene id: 630626:EBL_RS02710
uniprot id: I2B586
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

630626:EBL RS14645
gene id: 630626:EBL_RS14645
uniprot id: I2BC44
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

630626:EBL RS15610
gene id: 630626:EBL_RS15610
uniprot id: I2BCN6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

630626:EBL RS16015
gene id: 630626:EBL_RS16015
uniprot id: I2BCW8
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

630626:EBL RS07530
gene id: 630626:EBL_RS07530
uniprot id: I2B803
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS03385
gene id: 630626:EBL_RS03385
uniprot id: I2B5M7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS08715
gene id: 630626:EBL_RS08715
uniprot id: I2B8P6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

630626:EBL RS15620
gene id: 630626:EBL_RS15620
uniprot id: I2BCN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS07445
gene id: 630626:EBL_RS07445
uniprot id: I2B7Y9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

630626:EBL RS11055
gene id: 630626:EBL_RS11055
uniprot id: I2BA27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

630626:EBL RS00660
gene id: 630626:EBL_RS00660
uniprot id: I2B420
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

630626:EBL RS08590
gene id: 630626:EBL_RS08590
uniprot id: I2B8M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

630626:EBL RS17415
gene id: 630626:EBL_RS17415
uniprot id: I2BDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell inner membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

630626:EBL RS00080
gene id: 630626:EBL_RS00080
uniprot id: I2B3P9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS13655
gene id: 630626:EBL_RS13655
uniprot id: I2BBJ0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11190
gene id: 630626:EBL_RS11190
uniprot id: I2BA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

630626:EBL RS07420
gene id: 630626:EBL_RS07420
uniprot id: I2B7Y4
names: Similarity
messages: Belongs to the DsrB family.

630626:EBL RS15115
gene id: 630626:EBL_RS15115
uniprot id: I2BCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

630626:EBL RS12765
gene id: 630626:EBL_RS12765
uniprot id: I2BB23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS13030
gene id: 630626:EBL_RS13030
uniprot id: I2BB70
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

630626:EBL RS11185
gene id: 630626:EBL_RS11185
uniprot id: I2BA51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

630626:EBL RS01395
gene id: 630626:EBL_RS01395
uniprot id: I2B4H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

630626:EBL RS04435
gene id: 630626:EBL_RS04435
uniprot id: I2B689
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

630626:EBL RS06775
gene id: 630626:EBL_RS06775
uniprot id: I2B7K7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

630626:EBL RS08100
gene id: 630626:EBL_RS08100
uniprot id: I2B8B9
names: Similarity
messages: Belongs to the SufE family.

630626:EBL RS16260
gene id: 630626:EBL_RS16260
uniprot id: I2BD17
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

630626:EBL RS14135
gene id: 630626:EBL_RS14135
uniprot id: I2BBT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS18220
gene id: 630626:EBL_RS18220
uniprot id: I2BE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

630626:EBL RS15295
gene id: 630626:EBL_RS15295
uniprot id: I2BCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS09730
gene id: 630626:EBL_RS09730
uniprot id: I2B9A1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.
messages: Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
messages: Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homotetramer.

630626:EBL RS17730
gene id: 630626:EBL_RS17730
uniprot id: I2BDV9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

630626:EBL RS07185
gene id: 630626:EBL_RS07185
uniprot id: I2B7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

630626:EBL RS18060
gene id: 630626:EBL_RS18060
uniprot id: I2BE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

630626:EBL RS15700
gene id: 630626:EBL_RS15700
uniprot id: I2BCQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

630626:EBL RS15005
gene id: 630626:EBL_RS15005
uniprot id: I2BCB9
names: Similarity
messages: Belongs to the CdaR family.

630626:EBL RS12835
gene id: 630626:EBL_RS12835
uniprot id: I2BB30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

630626:EBL RS03575
gene id: 630626:EBL_RS03575
uniprot id: I2B5R7
names: Similarity
messages: Belongs to the CcmL/EutN family.

630626:EBL RS06165
gene id: 630626:EBL_RS06165
uniprot id: I2B784
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

630626:EBL RS16580
gene id: 630626:EBL_RS16580
uniprot id: I2BD80
names: Similarity
messages: Belongs to the asparaginase 1 family.

630626:EBL RS04335
gene id: 630626:EBL_RS04335
uniprot id: I2B667
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

630626:EBL RS16145
gene id: 630626:EBL_RS16145
uniprot id: I2BCZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS09435
gene id: 630626:EBL_RS09435
uniprot id: I2B942
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

630626:EBL RS13035
gene id: 630626:EBL_RS13035
uniprot id: I2BB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class A bacterial acid phosphatase family.
messages: Periplasm

630626:EBL RS17185
gene id: 630626:EBL_RS17185
uniprot id: I2BDJ8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS04000
gene id: 630626:EBL_RS04000
uniprot id: I2B603
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

630626:EBL RS07635
gene id: 630626:EBL_RS07635
uniprot id: I2B825
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS06490
gene id: 630626:EBL_RS06490
uniprot id: I2B7F0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

630626:EBL RS04430
gene id: 630626:EBL_RS04430
uniprot id: I2B688
names: Similarity
messages: Belongs to the carbamate kinase family.

630626:EBL RS02020
gene id: 630626:EBL_RS02020
uniprot id: I2B4U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

630626:EBL RS19080
gene id: 630626:EBL_RS19080
uniprot id: I2BEL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS16540
gene id: 630626:EBL_RS16540
uniprot id: I2BD72
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

630626:EBL RS05670
gene id: 630626:EBL_RS05670
uniprot id: I2B6Y5
names: Similarity
messages: Belongs to the VgrG protein family.

630626:EBL RS03325
gene id: 630626:EBL_RS03325
uniprot id: I2B5L3
names: Similarity
messages: Belongs to the RecJ family.

630626:EBL RS16835
gene id: 630626:EBL_RS16835
uniprot id: I2BDC7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

630626:EBL RS03440
gene id: 630626:EBL_RS03440
uniprot id: I2B5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

630626:EBL RS11790
gene id: 630626:EBL_RS11790
uniprot id: I2BAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

630626:EBL RS12770
gene id: 630626:EBL_RS12770
uniprot id: I2BB24
names: Similarity
messages: Belongs to the aldose epimerase family.

630626:EBL RS20025
gene id: 630626:EBL_RS20025
uniprot id: I2BAR6
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS11905
gene id: 630626:EBL_RS11905
uniprot id: I2BAJ5
names: Similarity
messages: Belongs to the acylphosphatase family.

630626:EBL RS08310
gene id: 630626:EBL_RS08310
uniprot id: I2B8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Periplasm

630626:EBL RS07055
gene id: 630626:EBL_RS07055
uniprot id: I2B7R3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

630626:EBL RS03210
gene id: 630626:EBL_RS03210
uniprot id: I2B5J0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

630626:EBL RS12030
gene id: 630626:EBL_RS12030
uniprot id: I2BAM1
names: Similarity
messages: Belongs to the peptidase M1 family.

630626:EBL RS18950
gene id: 630626:EBL_RS18950
uniprot id: I2BEI6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

630626:EBL RS19415
gene id: 630626:EBL_RS19415
uniprot id: I2BES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

630626:EBL RS09145
gene id: 630626:EBL_RS09145
uniprot id: I2B8Y1
names: Similarity
messages: Belongs to the UPF0225 family.

630626:EBL RS00625
gene id: 630626:EBL_RS00625
uniprot id: I2B413
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

630626:EBL RS09800
gene id: 630626:EBL_RS09800
uniprot id: I2B9B5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

630626:EBL RS11390
gene id: 630626:EBL_RS11390
uniprot id: I2BA93
names: Similarity
messages: Belongs to the UPF0229 family.

630626:EBL RS07845
gene id: 630626:EBL_RS07845
uniprot id: I2B867
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS10370
gene id: 630626:EBL_RS10370
uniprot id: I2B9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

630626:EBL RS15780
gene id: 630626:EBL_RS15780
uniprot id: I2BCS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

630626:EBL RS02905
gene id: 630626:EBL_RS02905
uniprot id: I2B5C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

630626:EBL RS06100
gene id: 630626:EBL_RS06100
uniprot id: I2B771
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS12915
gene id: 630626:EBL_RS12915
uniprot id: I2BB47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

630626:EBL RS15500
gene id: 630626:EBL_RS15500
uniprot id: I2BCL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

630626:EBL RS13785
gene id: 630626:EBL_RS13785
uniprot id: I2BBL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

630626:EBL RS03765
gene id: 630626:EBL_RS03765
uniprot id: I2B5V5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

630626:EBL RS18290
gene id: 630626:EBL_RS18290
uniprot id: I2BE61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS17115
gene id: 630626:EBL_RS17115
uniprot id: I2BDI4
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).

630626:EBL RS15980
gene id: 630626:EBL_RS15980
uniprot id: I2BCW1
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

630626:EBL RS02965
gene id: 630626:EBL_RS02965
uniprot id: I2B5D8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

630626:EBL RS11350
gene id: 630626:EBL_RS11350
uniprot id: I2BA85
names: Similarity
messages: Belongs to the asparaginase 1 family.

630626:EBL RS17015
gene id: 630626:EBL_RS17015
uniprot id: I2BDG4
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

630626:EBL RS06455
gene id: 630626:EBL_RS06455
uniprot id: I2B7E3
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS19110
gene id: 630626:EBL_RS19110
uniprot id: I2BEL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS17605
gene id: 630626:EBL_RS17605
uniprot id: I2BDT1
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

630626:EBL RS02775
gene id: 630626:EBL_RS02775
uniprot id: K6WK78
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

630626:EBL RS15680
gene id: 630626:EBL_RS15680
uniprot id: I2BCQ0
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

630626:EBL RS06265
gene id: 630626:EBL_RS06265
uniprot id: I2B7A6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS06815
gene id: 630626:EBL_RS06815
uniprot id: I2B7L5
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

630626:EBL RS09190
gene id: 630626:EBL_RS09190
uniprot id: I2B8Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

630626:EBL RS04320
gene id: 630626:EBL_RS04320
uniprot id: I2B664
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

630626:EBL RS18460
gene id: 630626:EBL_RS18460
uniprot id: I2BE92
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS12365
gene id: 630626:EBL_RS12365
uniprot id: I2BAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

630626:EBL RS01775
gene id: 630626:EBL_RS01775
uniprot id: I2B4P2
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS15900
gene id: 630626:EBL_RS15900
uniprot id: I2BCU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

630626:EBL RS00440
gene id: 630626:EBL_RS00440
uniprot id: I2B3X6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

630626:EBL RS12670
gene id: 630626:EBL_RS12670
uniprot id: I2BB01
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

630626:EBL RS11725
gene id: 630626:EBL_RS11725
uniprot id: I2BAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS13980
gene id: 630626:EBL_RS13980
uniprot id: I2BBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

630626:EBL RS18805
gene id: 630626:EBL_RS18805
uniprot id: I2BEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

630626:EBL RS06900
gene id: 630626:EBL_RS06900
uniprot id: I2B7N3
names: Subcellular Location Annotation
messages: Cell inner membrane

630626:EBL RS08080
gene id: 630626:EBL_RS08080
uniprot id: I2B8B5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

630626:EBL RS19085
gene id: 630626:EBL_RS19085
uniprot id: I2BEL4
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

630626:EBL RS19270
gene id: 630626:EBL_RS19270
uniprot id: I2BEP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

630626:EBL RS01610
gene id: 630626:EBL_RS01610
uniprot id: I2B4K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

630626:EBL RS13855
gene id: 630626:EBL_RS13855
uniprot id: I2BBN0
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

630626:EBL RS15460
gene id: 630626:EBL_RS15460
uniprot id: I2BCK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

630626:EBL RS16930
gene id: 630626:EBL_RS16930
uniprot id: I2BDE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

630626:EBL RS06075
gene id: 630626:EBL_RS06075
uniprot id: I2B766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS03010
gene id: 630626:EBL_RS03010
uniprot id: I2B5E7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS08860
gene id: 630626:EBL_RS08860
uniprot id: I2B8S5
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

630626:EBL RS11520
gene id: 630626:EBL_RS11520
uniprot id: I2BAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

630626:EBL RS15865
gene id: 630626:EBL_RS15865
uniprot id: I2BCT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

630626:EBL RS00850
gene id: 630626:EBL_RS00850
uniprot id: I2B458
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

630626:EBL RS10300
gene id: 630626:EBL_RS10300
uniprot id: I2B9M4
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

630626:EBL RS07755
gene id: 630626:EBL_RS07755
uniprot id: I2B849
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

630626:EBL RS16490
gene id: 630626:EBL_RS16490
uniprot id: I2BD62
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08725
gene id: 630626:EBL_RS08725
uniprot id: I2B8P8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

630626:EBL RS18030
gene id: 630626:EBL_RS18030
uniprot id: I2BE16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

630626:EBL RS18055
gene id: 630626:EBL_RS18055
uniprot id: I2BE21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS09020
gene id: 630626:EBL_RS09020
uniprot id: I2B8V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

630626:EBL RS11315
gene id: 630626:EBL_RS11315
uniprot id: I2BA78
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

630626:EBL RS10555
gene id: 630626:EBL_RS10555
uniprot id: I2B9S7
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

630626:EBL RS08305
gene id: 630626:EBL_RS08305
uniprot id: I2B8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

630626:EBL RS07675
gene id: 630626:EBL_RS07675
uniprot id: I2B833
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

630626:EBL RS07345
gene id: 630626:EBL_RS07345
uniprot id: I2B7X0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS17800
gene id: 630626:EBL_RS17800
uniprot id: I2BDX3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.
messages: Membrane

630626:EBL RS12275
gene id: 630626:EBL_RS12275
uniprot id: I2BAS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

630626:EBL RS09015
gene id: 630626:EBL_RS09015
uniprot id: I2B8V6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

630626:EBL RS10715
gene id: 630626:EBL_RS10715
uniprot id: I2B9V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS12960
gene id: 630626:EBL_RS12960
uniprot id: I2BB56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

630626:EBL RS15995
gene id: 630626:EBL_RS15995
uniprot id: I2BCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with the regulatory subunit KefF.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

630626:EBL RS07060
gene id: 630626:EBL_RS07060
uniprot id: I2B7R4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

630626:EBL RS17835
gene id: 630626:EBL_RS17835
uniprot id: I2BDY1
names: Similarity
messages: Belongs to the aspartokinase family.

630626:EBL RS13625
gene id: 630626:EBL_RS13625
uniprot id: I2BBI4
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS02890
gene id: 630626:EBL_RS02890
uniprot id: I2B5C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

630626:EBL RS01025
gene id: 630626:EBL_RS01025
uniprot id: I2B494
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

630626:EBL RS07160
gene id: 630626:EBL_RS07160
uniprot id: I2B7T4
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

630626:EBL RS16005
gene id: 630626:EBL_RS16005
uniprot id: I2BCW6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15345
gene id: 630626:EBL_RS15345
uniprot id: I2BCI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

630626:EBL RS05870
gene id: 630626:EBL_RS05870
uniprot id: I2B724
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YfcJ family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS02725
gene id: 630626:EBL_RS02725
uniprot id: I2B589
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

630626:EBL RS06800
gene id: 630626:EBL_RS06800
uniprot id: I2B7L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

630626:EBL RS01340
gene id: 630626:EBL_RS01340
uniprot id: I2B4G0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

630626:EBL RS17390
gene id: 630626:EBL_RS17390
uniprot id: I2BDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

630626:EBL RS12315
gene id: 630626:EBL_RS12315
uniprot id: I2BAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS04570
gene id: 630626:EBL_RS04570
uniprot id: I2B6B7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

630626:EBL RS12080
gene id: 630626:EBL_RS12080
uniprot id: I2BAN1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

630626:EBL RS02850
gene id: 630626:EBL_RS02850
uniprot id: I2B5B5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

630626:EBL RS08585
gene id: 630626:EBL_RS08585
uniprot id: I2B8L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

630626:EBL RS03335
gene id: 630626:EBL_RS03335
uniprot id: I2B5L5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS18420
gene id: 630626:EBL_RS18420
uniprot id: I2BE84
names: Similarity
messages: Belongs to the thioredoxin family.

630626:EBL RS09105
gene id: 630626:EBL_RS09105
uniprot id: I2B8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS13840
gene id: 630626:EBL_RS13840
uniprot id: I2BBM7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

630626:EBL RS06950
gene id: 630626:EBL_RS06950
uniprot id: I2B7P3
names: Similarity
messages: Belongs to the UPF0053 family.

630626:EBL RS13965
gene id: 630626:EBL_RS13965
uniprot id: I2BBQ4
names: Similarity
messages: Belongs to the BolA/IbaG family.

630626:EBL RS07650
gene id: 630626:EBL_RS07650
uniprot id: I2B828
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

630626:EBL RS14785
gene id: 630626:EBL_RS14785
uniprot id: I2BC72
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

630626:EBL RS13350
gene id: 630626:EBL_RS13350
uniprot id: I2BBD0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS02310
gene id: 630626:EBL_RS02310
uniprot id: I2B4Z9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS00215
gene id: 630626:EBL_RS00215
uniprot id: I2B3S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS15970
gene id: 630626:EBL_RS15970
uniprot id: I2BCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

630626:EBL RS01535
gene id: 630626:EBL_RS01535
uniprot id: I2B4K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

630626:EBL RS18395
gene id: 630626:EBL_RS18395
uniprot id: I2BE79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

630626:EBL RS08835
gene id: 630626:EBL_RS08835
uniprot id: I2B8S0
names: Similarity
messages: Belongs to the HupJ family.

630626:EBL RS01965
gene id: 630626:EBL_RS01965
uniprot id: I2B4T0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS07600
gene id: 630626:EBL_RS07600
uniprot id: I2B818
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS05295
gene id: 630626:EBL_RS05295
uniprot id: I2B6R4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

630626:EBL RS06410
gene id: 630626:EBL_RS06410
uniprot id: I2B7D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

630626:EBL RS13195
gene id: 630626:EBL_RS13195
uniprot id: I2BB95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

630626:EBL RS09370
gene id: 630626:EBL_RS09370
uniprot id: I2B928
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

630626:EBL RS19365
gene id: 630626:EBL_RS19365
uniprot id: I2BER9
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS07725
gene id: 630626:EBL_RS07725
uniprot id: I2B843
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

630626:EBL RS04745
gene id: 630626:EBL_RS04745
uniprot id: I2B6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

630626:EBL RS09175
gene id: 630626:EBL_RS09175
uniprot id: I2B8Y7
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

630626:EBL RS10965
gene id: 630626:EBL_RS10965
uniprot id: I2BA09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

630626:EBL RS01245
gene id: 630626:EBL_RS01245
uniprot id: I2B4E2
names: Similarity
messages: Belongs to the phosphoribulokinase family.

630626:EBL RS13715
gene id: 630626:EBL_RS13715
uniprot id: I2BBK2
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

630626:EBL RS17000
gene id: 630626:EBL_RS17000
uniprot id: I2BDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

630626:EBL RS12660
gene id: 630626:EBL_RS12660
uniprot id: I2BAZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

630626:EBL RS17635
gene id: 630626:EBL_RS17635
uniprot id: I2BDT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

630626:EBL RS18140
gene id: 630626:EBL_RS18140
uniprot id: I2BE31
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

630626:EBL RS11110
gene id: 630626:EBL_RS11110
uniprot id: I2BA38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

630626:EBL RS05190
gene id: 630626:EBL_RS05190
uniprot id: I2B6P3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

630626:EBL RS05195
gene id: 630626:EBL_RS05195
uniprot id: I2B6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

630626:EBL RS19320
gene id: 630626:EBL_RS19320
uniprot id: I2BEQ9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS16905
gene id: 630626:EBL_RS16905
uniprot id: I2BDE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

630626:EBL RS10785
gene id: 630626:EBL_RS10785
uniprot id: I2B9X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

630626:EBL RS13955
gene id: 630626:EBL_RS13955
uniprot id: I2BBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

630626:EBL RS04800
gene id: 630626:EBL_RS04800
uniprot id: I2B6F9
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

630626:EBL RS09395
gene id: 630626:EBL_RS09395
uniprot id: I2B934
names: Similarity
messages: Belongs to the YjiK family.

630626:EBL RS05360
gene id: 630626:EBL_RS05360
uniprot id: I2B6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

630626:EBL RS15475
gene id: 630626:EBL_RS15475
uniprot id: I2BCK9
names: Similarity
messages: Belongs to the UPF0325 family.

630626:EBL RS00710
gene id: 630626:EBL_RS00710
uniprot id: I2B429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS02480
gene id: 630626:EBL_RS02480
uniprot id: I2B538
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

630626:EBL RS15650
gene id: 630626:EBL_RS15650
uniprot id: I2BCP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS00060
gene id: 630626:EBL_RS00060
uniprot id: I2B3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane

630626:EBL RS08190
gene id: 630626:EBL_RS08190
uniprot id: I2B8D8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

630626:EBL RS05265
gene id: 630626:EBL_RS05265
uniprot id: I2B6Q8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

630626:EBL RS06105
gene id: 630626:EBL_RS06105
uniprot id: I2B772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

630626:EBL RS03955
gene id: 630626:EBL_RS03955
uniprot id: I2B5Z3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS16925
gene id: 630626:EBL_RS16925
uniprot id: I2BDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

630626:EBL RS18095
gene id: 630626:EBL_RS18095
uniprot id: I2BE26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

630626:EBL RS08950
gene id: 630626:EBL_RS08950
uniprot id: I2B8U3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

630626:EBL RS15855
gene id: 630626:EBL_RS15855
uniprot id: I2BCT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

630626:EBL RS02605
gene id: 630626:EBL_RS02605
uniprot id: I2B565
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

630626:EBL RS01090
gene id: 630626:EBL_RS01090
uniprot id: I2B4A8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

630626:EBL RS06570
gene id: 630626:EBL_RS06570
uniprot id: I2B7G6
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

630626:EBL RS14145
gene id: 630626:EBL_RS14145
uniprot id: I2BBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

630626:EBL RS11220
gene id: 630626:EBL_RS11220
uniprot id: I2BA58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

630626:EBL RS09110
gene id: 630626:EBL_RS09110
uniprot id: I2B8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

630626:EBL RS00460
gene id: 630626:EBL_RS00460
uniprot id: I2B3Y0
names: Similarity
messages: Belongs to the HupF/HypC family.

630626:EBL RS07070
gene id: 630626:EBL_RS07070
uniprot id: I2B7R6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06825
gene id: 630626:EBL_RS06825
uniprot id: I2B7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

630626:EBL RS05150
gene id: 630626:EBL_RS05150
uniprot id: I2B6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

630626:EBL RS07095
gene id: 630626:EBL_RS07095
uniprot id: I2B7S1
names: Similarity
messages: Belongs to the UPF0265 family.

630626:EBL RS12920
gene id: 630626:EBL_RS12920
uniprot id: I2BB48
names: Similarity
messages: Belongs to the citrate synthase family.

630626:EBL RS14690
gene id: 630626:EBL_RS14690
uniprot id: I2BC53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

630626:EBL RS16720
gene id: 630626:EBL_RS16720
uniprot id: I2BDA5
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11530
gene id: 630626:EBL_RS11530
uniprot id: I2BAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

630626:EBL RS09070
gene id: 630626:EBL_RS09070
uniprot id: I2B8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

630626:EBL RS00050
gene id: 630626:EBL_RS00050
uniprot id: I2B3P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

630626:EBL RS14000
gene id: 630626:EBL_RS14000
uniprot id: I2BBR1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

630626:EBL RS03840
gene id: 630626:EBL_RS03840
uniprot id: I2B5X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS01920
gene id: 630626:EBL_RS01920
uniprot id: I2B4S1
names: Similarity
messages: Belongs to the peptidase S13 family.

630626:EBL RS05280
gene id: 630626:EBL_RS05280
uniprot id: I2B6R1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS14885
gene id: 630626:EBL_RS14885
uniprot id: I2BC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

630626:EBL RS08015
gene id: 630626:EBL_RS08015
uniprot id: I2B8A1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

630626:EBL RS01165
gene id: 630626:EBL_RS01165
uniprot id: I2B4C3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

630626:EBL RS17890
gene id: 630626:EBL_RS17890
uniprot id: I2BDZ2
names: Similarity
messages: Belongs to the malate synthase family.

630626:EBL RS06480
gene id: 630626:EBL_RS06480
uniprot id: I2B7E8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

630626:EBL RS14705
gene id: 630626:EBL_RS14705
uniprot id: I2BC56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

630626:EBL RS13265
gene id: 630626:EBL_RS13265
uniprot id: I2BBB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

630626:EBL RS02350
gene id: 630626:EBL_RS02350
uniprot id: I2B510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

630626:EBL RS11650
gene id: 630626:EBL_RS11650
uniprot id: I2BAE7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

630626:EBL RS15405
gene id: 630626:EBL_RS15405
uniprot id: I2BCJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

630626:EBL RS00180
gene id: 630626:EBL_RS00180
uniprot id: I2B3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS12625
gene id: 630626:EBL_RS12625
uniprot id: I2BAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS01780
gene id: 630626:EBL_RS01780
uniprot id: I2B4P3
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

630626:EBL RS09815
gene id: 630626:EBL_RS09815
uniprot id: I2B9B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS00915
gene id: 630626:EBL_RS00915
uniprot id: I2B472
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS04995
gene id: 630626:EBL_RS04995
uniprot id: I2B6K1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

630626:EBL RS00760
gene id: 630626:EBL_RS00760
uniprot id: I2B439
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Cytoplasm
messages: Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
messages: Monomer.

630626:EBL RS13240
gene id: 630626:EBL_RS13240
uniprot id: I2BBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

630626:EBL RS03925
gene id: 630626:EBL_RS03925
uniprot id: I2B5Y6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

630626:EBL RS11020
gene id: 630626:EBL_RS11020
uniprot id: I2BA20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

630626:EBL RS14950
gene id: 630626:EBL_RS14950
uniprot id: I2BCA8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS01215
gene id: 630626:EBL_RS01215
uniprot id: I2B4D5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

630626:EBL RS01315
gene id: 630626:EBL_RS01315
uniprot id: I2B4F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

630626:EBL RS05825
gene id: 630626:EBL_RS05825
uniprot id: I2B715
names: Similarity
messages: Belongs to the UPF0115 family.

630626:EBL RS13690
gene id: 630626:EBL_RS13690
uniprot id: I2BBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

630626:EBL RS09720
gene id: 630626:EBL_RS09720
uniprot id: I2B998
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

630626:EBL RS02460
gene id: 630626:EBL_RS02460
uniprot id: I2B534
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS14055
gene id: 630626:EBL_RS14055
uniprot id: I2BBS2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

630626:EBL RS03770
gene id: 630626:EBL_RS03770
uniprot id: I2B5V6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

630626:EBL RS13290
gene id: 630626:EBL_RS13290
uniprot id: I2BBB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

630626:EBL RS00285
gene id: 630626:EBL_RS00285
uniprot id: I2B3U5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

630626:EBL RS02130
gene id: 630626:EBL_RS02130
uniprot id: I2B4W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

630626:EBL RS16955
gene id: 630626:EBL_RS16955
uniprot id: I2BDF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

630626:EBL RS15420
gene id: 630626:EBL_RS15420
uniprot id: I2BCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

630626:EBL RS04680
gene id: 630626:EBL_RS04680
uniprot id: I2B6D4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

630626:EBL RS11590
gene id: 630626:EBL_RS11590
uniprot id: I2BAD4
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06695
gene id: 630626:EBL_RS06695
uniprot id: I2B7J1
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

630626:EBL RS04565
gene id: 630626:EBL_RS04565
uniprot id: I2B6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

630626:EBL RS20055
gene id: 630626:EBL_RS20055
uniprot id: I2BB18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell inner membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

630626:EBL RS15090
gene id: 630626:EBL_RS15090
uniprot id: I2BCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

630626:EBL RS18045
gene id: 630626:EBL_RS18045
uniprot id: I2BE19
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

630626:EBL RS03700
gene id: 630626:EBL_RS03700
uniprot id: I2B5U2
names: Similarity
messages: Belongs to the creatininase superfamily.

630626:EBL RS00845
gene id: 630626:EBL_RS00845
uniprot id: I2B457
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

630626:EBL RS16960
gene id: 630626:EBL_RS16960
uniprot id: I2BDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

630626:EBL RS07560
gene id: 630626:EBL_RS07560
uniprot id: I2B810
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS09615
gene id: 630626:EBL_RS09615
uniprot id: I2B976
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

630626:EBL RS00600
gene id: 630626:EBL_RS00600
uniprot id: I2B408
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS18185
gene id: 630626:EBL_RS18185
uniprot id: I2BE40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS15070
gene id: 630626:EBL_RS15070
uniprot id: I2BCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

630626:EBL RS15305
gene id: 630626:EBL_RS15305
uniprot id: I2BCH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

630626:EBL RS18535
gene id: 630626:EBL_RS18535
uniprot id: I2BEA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS09090
gene id: 630626:EBL_RS09090
uniprot id: I2B8X2
names: Similarity
messages: Belongs to the intimin/invasin family.

630626:EBL RS17870
gene id: 630626:EBL_RS17870
uniprot id: I2BDY8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

630626:EBL RS11835
gene id: 630626:EBL_RS11835
uniprot id: I2BAI2
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

630626:EBL RS01055
gene id: 630626:EBL_RS01055
uniprot id: I2B4A0
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

630626:EBL RS16900
gene id: 630626:EBL_RS16900
uniprot id: I2BDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

630626:EBL RS02705
gene id: 630626:EBL_RS02705
uniprot id: I2B585
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

630626:EBL RS06280
gene id: 630626:EBL_RS06280
uniprot id: I2B7A9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

630626:EBL RS17760
gene id: 630626:EBL_RS17760
uniprot id: I2BDW5
names: Similarity
messages: Belongs to the Fur family.

630626:EBL RS15355
gene id: 630626:EBL_RS15355
uniprot id: I2BCI5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

630626:EBL RS17975
gene id: 630626:EBL_RS17975
uniprot id: I2BE05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

630626:EBL RS16240
gene id: 630626:EBL_RS16240
uniprot id: I2BD13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

630626:EBL RS10385
gene id: 630626:EBL_RS10385
uniprot id: I2B9P1
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

630626:EBL RS11810
gene id: 630626:EBL_RS11810
uniprot id: I2BAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

630626:EBL RS16975
gene id: 630626:EBL_RS16975
uniprot id: I2BDF5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

630626:EBL RS15085
gene id: 630626:EBL_RS15085
uniprot id: I2BCD6
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

630626:EBL RS17110
gene id: 630626:EBL_RS17110
uniprot id: I2BDI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

630626:EBL RS10990
gene id: 630626:EBL_RS10990
uniprot id: I2BA14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

630626:EBL RS06990
gene id: 630626:EBL_RS06990
uniprot id: I2B7Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

630626:EBL RS04915
gene id: 630626:EBL_RS04915
uniprot id: I2B6I5
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

630626:EBL RS04715
gene id: 630626:EBL_RS04715
uniprot id: I2B6E2
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

630626:EBL RS04765
gene id: 630626:EBL_RS04765
uniprot id: I2B6F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

630626:EBL RS12320
gene id: 630626:EBL_RS12320
uniprot id: I2BAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

630626:EBL RS03550
gene id: 630626:EBL_RS03550
uniprot id: I2B5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

630626:EBL RS07120
gene id: 630626:EBL_RS07120
uniprot id: I2B7S6
names: Similarity
messages: Belongs to the CobH/CbiC family.

630626:EBL RS08905
gene id: 630626:EBL_RS08905
uniprot id: I2B8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA).

630626:EBL RS15450
gene id: 630626:EBL_RS15450
uniprot id: I2BCK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

630626:EBL RS07025
gene id: 630626:EBL_RS07025
uniprot id: I2B7Q7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

630626:EBL RS04635
gene id: 630626:EBL_RS04635
uniprot id: I2B6D0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

630626:EBL RS11980
gene id: 630626:EBL_RS11980
uniprot id: I2BAL0
names: Similarity
messages: Belongs to the peptidase S16 family.

630626:EBL RS09630
gene id: 630626:EBL_RS09630
uniprot id: I2B980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

630626:EBL RS19265
gene id: 630626:EBL_RS19265
uniprot id: I2BEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

630626:EBL RS03620
gene id: 630626:EBL_RS03620
uniprot id: I2B5S6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

630626:EBL RS06370
gene id: 630626:EBL_RS06370
uniprot id: I2B7C6
names: Similarity
messages: Belongs to the UPF0352 family.

630626:EBL RS07510
gene id: 630626:EBL_RS07510
uniprot id: I2B7Z9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS02885
gene id: 630626:EBL_RS02885
uniprot id: I2B5C2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

630626:EBL RS11715
gene id: 630626:EBL_RS11715
uniprot id: I2BAG0
names: Similarity
messages: Belongs to the UPF0502 family.

630626:EBL RS09065
gene id: 630626:EBL_RS09065
uniprot id: I2B8W7
names: Similarity
messages: Belongs to the UPF0162 family.

630626:EBL RS18905
gene id: 630626:EBL_RS18905
uniprot id: I2BEH7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

630626:EBL RS17735
gene id: 630626:EBL_RS17735
uniprot id: I2BDW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. DnaB subfamily.
messages: Homohexamer.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

630626:EBL RS01940
gene id: 630626:EBL_RS01940
uniprot id: I2B4S5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS03170
gene id: 630626:EBL_RS03170
uniprot id: I2B5I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

630626:EBL RS08180
gene id: 630626:EBL_RS08180
uniprot id: I2B8D6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS11575
gene id: 630626:EBL_RS11575
uniprot id: I2BAD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoB family.
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

630626:EBL RS01450
gene id: 630626:EBL_RS01450
uniprot id: I2B4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

630626:EBL RS13390
gene id: 630626:EBL_RS13390
uniprot id: I2BBD8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15815
gene id: 630626:EBL_RS15815
uniprot id: I2BCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS18355
gene id: 630626:EBL_RS18355
uniprot id: I2BE71
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

630626:EBL RS11095
gene id: 630626:EBL_RS11095
uniprot id: I2BA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS09520
gene id: 630626:EBL_RS09520
uniprot id: I2B959
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

630626:EBL RS12265
gene id: 630626:EBL_RS12265
uniprot id: I2BAR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS02580
gene id: 630626:EBL_RS02580
uniprot id: I2B559
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS02630
gene id: 630626:EBL_RS02630
uniprot id: I2B570
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

630626:EBL RS14105
gene id: 630626:EBL_RS14105
uniprot id: I2BBT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

630626:EBL RS14700
gene id: 630626:EBL_RS14700
uniprot id: I2BC55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

630626:EBL RS03190
gene id: 630626:EBL_RS03190
uniprot id: I2B5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

630626:EBL RS06260
gene id: 630626:EBL_RS06260
uniprot id: I2B7A5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

630626:EBL RS12775
gene id: 630626:EBL_RS12775
uniprot id: I2BB25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

630626:EBL RS10825
gene id: 630626:EBL_RS10825
uniprot id: I2B9Y0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

630626:EBL RS12595
gene id: 630626:EBL_RS12595
uniprot id: I2BAY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

630626:EBL RS17375
gene id: 630626:EBL_RS17375
uniprot id: I2BDN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

630626:EBL RS00140
gene id: 630626:EBL_RS00140
uniprot id: I2B3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

630626:EBL RS14600
gene id: 630626:EBL_RS14600
uniprot id: I2BC34
names: Similarity
messages: Belongs to the diol/glycerol dehydratase large subunit family.

630626:EBL RS19405
gene id: 630626:EBL_RS19405
uniprot id: I2BES7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

630626:EBL RS07690
gene id: 630626:EBL_RS07690
uniprot id: I2B836
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS13615
gene id: 630626:EBL_RS13615
uniprot id: I2BBI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

630626:EBL RS00840
gene id: 630626:EBL_RS00840
uniprot id: I2B456
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

630626:EBL RS12225
gene id: 630626:EBL_RS12225
uniprot id: I2BAR0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06135
gene id: 630626:EBL_RS06135
uniprot id: I2B778
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS15670
gene id: 630626:EBL_RS15670
uniprot id: I2BCP8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

630626:EBL RS12650
gene id: 630626:EBL_RS12650
uniprot id: I2BAZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

630626:EBL RS07110
gene id: 630626:EBL_RS07110
uniprot id: I2B7S4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

630626:EBL RS14975
gene id: 630626:EBL_RS14975
uniprot id: I2BCB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

630626:EBL RS15170
gene id: 630626:EBL_RS15170
uniprot id: I2BCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS13775
gene id: 630626:EBL_RS13775
uniprot id: I2BBL3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

630626:EBL RS01350
gene id: 630626:EBL_RS01350
uniprot id: I2B4G2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

630626:EBL RS12990
gene id: 630626:EBL_RS12990
uniprot id: I2BB62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

630626:EBL RS06220
gene id: 630626:EBL_RS06220
uniprot id: I2B797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

630626:EBL RS02120
gene id: 630626:EBL_RS02120
uniprot id: I2B4W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

630626:EBL RS16515
gene id: 630626:EBL_RS16515
uniprot id: I2BD67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

630626:EBL RS10940
gene id: 630626:EBL_RS10940
uniprot id: I2BA04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

630626:EBL RS04090
gene id: 630626:EBL_RS04090
uniprot id: I2B622
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS15000
gene id: 630626:EBL_RS15000
uniprot id: I2BCB8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS10790
gene id: 630626:EBL_RS10790
uniprot id: I2B9X2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

630626:EBL RS06055
gene id: 630626:EBL_RS06055
uniprot id: I2B761
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS14210
gene id: 630626:EBL_RS14210
uniprot id: I2BBV2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

630626:EBL RS09050
gene id: 630626:EBL_RS09050
uniprot id: I2B8W4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

630626:EBL RS02925
gene id: 630626:EBL_RS02925
uniprot id: I2B5D0
names: Subunit
messages: Monomer.

630626:EBL RS11100
gene id: 630626:EBL_RS11100
uniprot id: I2BA36
names: Similarity
messages: Belongs to the CFA/CMAS family.

630626:EBL RS11490
gene id: 630626:EBL_RS11490
uniprot id: I2BAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS17215
gene id: 630626:EBL_RS17215
uniprot id: I2BDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RIC family. YtfE subfamily.
messages: Cytoplasm
messages: Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
messages: Homodimer.

630626:EBL RS13430
gene id: 630626:EBL_RS13430
uniprot id: I2BBE6
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06110
gene id: 630626:EBL_RS06110
uniprot id: I2B773
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS15380
gene id: 630626:EBL_RS15380
uniprot id: I2BCJ0
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS01690
gene id: 630626:EBL_RS01690
uniprot id: I2B4M4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS11805
gene id: 630626:EBL_RS11805
uniprot id: I2BAH8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

630626:EBL RS00305
gene id: 630626:EBL_RS00305
uniprot id: I2B3U9
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Membrane
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

630626:EBL RS10960
gene id: 630626:EBL_RS10960
uniprot id: I2BA08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

630626:EBL RS19180
gene id: 630626:EBL_RS19180
uniprot id: I2BEN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

630626:EBL RS04815
gene id: 630626:EBL_RS04815
uniprot id: I2B6G3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

630626:EBL RS02050
gene id: 630626:EBL_RS02050
uniprot id: I2B4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

630626:EBL RS13185
gene id: 630626:EBL_RS13185
uniprot id: I2BB93
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

630626:EBL RS14150
gene id: 630626:EBL_RS14150
uniprot id: I2BBU1
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

630626:EBL RS19395
gene id: 630626:EBL_RS19395
uniprot id: I2BES5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

630626:EBL RS10720
gene id: 630626:EBL_RS10720
uniprot id: I2B9V8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

630626:EBL RS07730
gene id: 630626:EBL_RS07730
uniprot id: I2B844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

630626:EBL RS01375
gene id: 630626:EBL_RS01375
uniprot id: I2B4G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

630626:EBL RS14040
gene id: 630626:EBL_RS14040
uniprot id: I2BBR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

630626:EBL RS11915
gene id: 630626:EBL_RS11915
uniprot id: I2BAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

630626:EBL RS15525
gene id: 630626:EBL_RS15525
uniprot id: I2BCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS01285
gene id: 630626:EBL_RS01285
uniprot id: I2B4F0
names: Similarity
messages: Belongs to the SlyX family.

630626:EBL RS13720
gene id: 630626:EBL_RS13720
uniprot id: I2BBK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

630626:EBL RS13040
gene id: 630626:EBL_RS13040
uniprot id: I2BB72
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS04355
gene id: 630626:EBL_RS04355
uniprot id: I2B671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS08480
gene id: 630626:EBL_RS08480
uniprot id: I2B8J7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS04555
gene id: 630626:EBL_RS04555
uniprot id: I2B6B4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

630626:EBL RS17970
gene id: 630626:EBL_RS17970
uniprot id: I2BE04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

630626:EBL RS06060
gene id: 630626:EBL_RS06060
uniprot id: I2B762
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS05845
gene id: 630626:EBL_RS05845
uniprot id: I2B719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS19580
gene id: 630626:EBL_RS19580
uniprot id: I2B514
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS10655
gene id: 630626:EBL_RS10655
uniprot id: I2B9U6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

630626:EBL RS13580
gene id: 630626:EBL_RS13580
uniprot id: I2BBH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS01360
gene id: 630626:EBL_RS01360
uniprot id: I2B4G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

630626:EBL RS03920
gene id: 630626:EBL_RS03920
uniprot id: I2B5Y5
names: Similarity
messages: Belongs to the SufE family.

630626:EBL RS01170
gene id: 630626:EBL_RS01170
uniprot id: I2B4C4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

630626:EBL RS18940
gene id: 630626:EBL_RS18940
uniprot id: I2BEI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

630626:EBL RS05840
gene id: 630626:EBL_RS05840
uniprot id: I2B718
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M74 family.
messages: Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.
messages: Dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
messages: Periplasm

630626:EBL RS10375
gene id: 630626:EBL_RS10375
uniprot id: I2B9N9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS13940
gene id: 630626:EBL_RS13940
uniprot id: I2BBP8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

630626:EBL RS09570
gene id: 630626:EBL_RS09570
uniprot id: I2B968
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

630626:EBL RS18190
gene id: 630626:EBL_RS18190
uniprot id: I2BE41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

630626:EBL RS00580
gene id: 630626:EBL_RS00580
uniprot id: I2B404
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

630626:EBL RS02340
gene id: 630626:EBL_RS02340
uniprot id: I2B507
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS10280
gene id: 630626:EBL_RS10280
uniprot id: I2B9M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

630626:EBL RS18310
gene id: 630626:EBL_RS18310
uniprot id: I2BE65
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

630626:EBL RS04235
gene id: 630626:EBL_RS04235
uniprot id: I2B652
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS03125
gene id: 630626:EBL_RS03125
uniprot id: I2B5H1
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

630626:EBL RS12035
gene id: 630626:EBL_RS12035
uniprot id: I2BAM2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

630626:EBL RS12115
gene id: 630626:EBL_RS12115
uniprot id: I2BAN8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS01420
gene id: 630626:EBL_RS01420
uniprot id: I2B4H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

630626:EBL RS18945
gene id: 630626:EBL_RS18945
uniprot id: I2BEI5
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

630626:EBL RS11370
gene id: 630626:EBL_RS11370
uniprot id: I2BA89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS19285
gene id: 630626:EBL_RS19285
uniprot id: I2BEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

630626:EBL RS19075
gene id: 630626:EBL_RS19075
uniprot id: I2BEL2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

630626:EBL RS08925
gene id: 630626:EBL_RS08925
uniprot id: I2B8T8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08720
gene id: 630626:EBL_RS08720
uniprot id: I2B8P7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

630626:EBL RS06920
gene id: 630626:EBL_RS06920
uniprot id: I2B7N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

630626:EBL RS19245
gene id: 630626:EBL_RS19245
uniprot id: I2BEP3
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS13920
gene id: 630626:EBL_RS13920
uniprot id: I2BBP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

630626:EBL RS13990
gene id: 630626:EBL_RS13990
uniprot id: I2BBQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

630626:EBL RS15195
gene id: 630626:EBL_RS15195
uniprot id: I2BCF9
names: Function
messages: May be involved in the biogenesis of curli organelles.

630626:EBL RS12550
gene id: 630626:EBL_RS12550
uniprot id: I2BAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

630626:EBL RS11755
gene id: 630626:EBL_RS11755
uniprot id: I2BAG8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

630626:EBL RS14630
gene id: 630626:EBL_RS14630
uniprot id: I2BC40
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

630626:EBL RS02295
gene id: 630626:EBL_RS02295
uniprot id: I2B4Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS06965
gene id: 630626:EBL_RS06965
uniprot id: I2B7P6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

630626:EBL RS03720
gene id: 630626:EBL_RS03720
uniprot id: I2B5U6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

630626:EBL RS13800
gene id: 630626:EBL_RS13800
uniprot id: I2BBL8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

630626:EBL RS15730
gene id: 630626:EBL_RS15730
uniprot id: I2BCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS18215
gene id: 630626:EBL_RS18215
uniprot id: I2BE46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

630626:EBL RS10195
gene id: 630626:EBL_RS10195
uniprot id: I2B9K3
names: Similarity
messages: Belongs to the CcdB toxin family.

630626:EBL RS04840
gene id: 630626:EBL_RS04840
uniprot id: I2B6G9
names: Similarity
messages: Belongs to the P(II) protein family.

630626:EBL RS04560
gene id: 630626:EBL_RS04560
uniprot id: I2B6B5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

630626:EBL RS01270
gene id: 630626:EBL_RS01270
uniprot id: I2B4E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

630626:EBL RS12440
gene id: 630626:EBL_RS12440
uniprot id: I2BAV4
names: Similarity
messages: Belongs to the GST superfamily.

630626:EBL RS01505
gene id: 630626:EBL_RS01505
uniprot id: I2B4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

630626:EBL RS06795
gene id: 630626:EBL_RS06795
uniprot id: I2B7L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PDR/VanB family. CntB subfamily.
messages: Binds 1 2Fe-2S cluster.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

630626:EBL RS11215
gene id: 630626:EBL_RS11215
uniprot id: I2BA57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

630626:EBL RS13165
gene id: 630626:EBL_RS13165
uniprot id: I2BB89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

630626:EBL RS07685
gene id: 630626:EBL_RS07685
uniprot id: I2B835
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

630626:EBL RS02590
gene id: 630626:EBL_RS02590
uniprot id: I2B561
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15310
gene id: 630626:EBL_RS15310
uniprot id: I2BCH6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

630626:EBL RS17120
gene id: 630626:EBL_RS17120
uniprot id: I2BDI5
names: Similarity
messages: Belongs to the UPF0307 family.

630626:EBL RS06285
gene id: 630626:EBL_RS06285
uniprot id: I2B7B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

630626:EBL RS05530
gene id: 630626:EBL_RS05530
uniprot id: I2B6V5
names: Similarity
messages: Belongs to the VgrG protein family.

630626:EBL RS11065
gene id: 630626:EBL_RS11065
uniprot id: I2BA29
names: Similarity
messages: Belongs to the peptidase C40 family.

630626:EBL RS01085
gene id: 630626:EBL_RS01085
uniprot id: I2B4A7
names: Subcellular Location Annotation
messages: Cell inner membrane

630626:EBL RS00365
gene id: 630626:EBL_RS00365
uniprot id: I2B3W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm
messages: Homotetramer.

630626:EBL RS01190
gene id: 630626:EBL_RS01190
uniprot id: I2B4C8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

630626:EBL RS17815
gene id: 630626:EBL_RS17815
uniprot id: I2BDX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

630626:EBL RS13795
gene id: 630626:EBL_RS13795
uniprot id: I2BBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

630626:EBL RS18835
gene id: 630626:EBL_RS18835
uniprot id: I2BEG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

630626:EBL RS12490
gene id: 630626:EBL_RS12490
uniprot id: I2BAW4
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS19650
gene id: 630626:EBL_RS19650
uniprot id: I2B615
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

630626:EBL RS08075
gene id: 630626:EBL_RS08075
uniprot id: I2B8B4
names: Similarity
messages: Belongs to the HesB/IscA family.

630626:EBL RS17545
gene id: 630626:EBL_RS17545
uniprot id: I2BDR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS18970
gene id: 630626:EBL_RS18970
uniprot id: I2BEJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

630626:EBL RS18735
gene id: 630626:EBL_RS18735
uniprot id: I2BEE3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

630626:EBL RS17160
gene id: 630626:EBL_RS17160
uniprot id: I2BDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

630626:EBL RS12025
gene id: 630626:EBL_RS12025
uniprot id: I2BAM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

630626:EBL RS19290
gene id: 630626:EBL_RS19290
uniprot id: I2BEQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

630626:EBL RS11845
gene id: 630626:EBL_RS11845
uniprot id: I2BAI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS08940
gene id: 630626:EBL_RS08940
uniprot id: I2B8U1
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS11935
gene id: 630626:EBL_RS11935
uniprot id: I2BAK1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

630626:EBL RS06635
gene id: 630626:EBL_RS06635
uniprot id: I2B7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

630626:EBL RS15745
gene id: 630626:EBL_RS15745
uniprot id: I2BCR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

630626:EBL RS20100
gene id: 630626:EBL_RS20100
uniprot id: I2BBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS11170
gene id: 630626:EBL_RS11170
uniprot id: I2BA48
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS16845
gene id: 630626:EBL_RS16845
uniprot id: I2BDC9
names: Similarity
messages: Belongs to the HsdR family.

630626:EBL RS02565
gene id: 630626:EBL_RS02565
uniprot id: I2B556
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

630626:EBL RS04980
gene id: 630626:EBL_RS04980
uniprot id: I2B6J8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS15820
gene id: 630626:EBL_RS15820
uniprot id: I2BCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

630626:EBL RS19250
gene id: 630626:EBL_RS19250
uniprot id: I2BEP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

630626:EBL RS04120
gene id: 630626:EBL_RS04120
uniprot id: I2B628
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

630626:EBL RS07620
gene id: 630626:EBL_RS07620
uniprot id: I2B822
names: Similarity
messages: Belongs to the fructosamine kinase family.

630626:EBL RS06515
gene id: 630626:EBL_RS06515
uniprot id: I2B7F5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

630626:EBL RS17445
gene id: 630626:EBL_RS17445
uniprot id: I2BDP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

630626:EBL RS13235
gene id: 630626:EBL_RS13235
uniprot id: I2BBA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

630626:EBL RS16470
gene id: 630626:EBL_RS16470
uniprot id: I2BD58
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06270
gene id: 630626:EBL_RS06270
uniprot id: I2B7A7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

630626:EBL RS03635
gene id: 630626:EBL_RS03635
uniprot id: I2B5S9
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

630626:EBL RS10880
gene id: 630626:EBL_RS10880
uniprot id: I2B9Z1
names: Similarity
messages: Belongs to the phosphopentomutase family.

630626:EBL RS00225
gene id: 630626:EBL_RS00225
uniprot id: I2B3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

630626:EBL RS05130
gene id: 630626:EBL_RS05130
uniprot id: I2B6N0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

630626:EBL RS04280
gene id: 630626:EBL_RS04280
uniprot id: I2B661
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

630626:EBL RS13120
gene id: 630626:EBL_RS13120
uniprot id: I2BB80
names: Similarity
messages: Belongs to the PhoH family.

630626:EBL RS03530
gene id: 630626:EBL_RS03530
uniprot id: I2B5Q8
names: Similarity
messages: Belongs to the ArsC family.

630626:EBL RS15675
gene id: 630626:EBL_RS15675
uniprot id: I2BCP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

630626:EBL RS06940
gene id: 630626:EBL_RS06940
uniprot id: I2B7P1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS15775
gene id: 630626:EBL_RS15775
uniprot id: I2BCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

630626:EBL RS10345
gene id: 630626:EBL_RS10345
uniprot id: I2B9N3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

630626:EBL RS16740
gene id: 630626:EBL_RS16740
uniprot id: I2BDA9
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS05080
gene id: 630626:EBL_RS05080
uniprot id: I2B6L8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

630626:EBL RS16305
gene id: 630626:EBL_RS16305
uniprot id: I2BD26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

630626:EBL RS04725
gene id: 630626:EBL_RS04725
uniprot id: I2B6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

630626:EBL RS02600
gene id: 630626:EBL_RS02600
uniprot id: I2B564
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

630626:EBL RS15440
gene id: 630626:EBL_RS15440
uniprot id: I2BCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

630626:EBL RS15395
gene id: 630626:EBL_RS15395
uniprot id: I2BCJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

630626:EBL RS07455
gene id: 630626:EBL_RS07455
uniprot id: I2B7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

630626:EBL RS02220
gene id: 630626:EBL_RS02220
uniprot id: I2B4Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

630626:EBL RS04330
gene id: 630626:EBL_RS04330
uniprot id: I2B666
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS15130
gene id: 630626:EBL_RS15130
uniprot id: I2BCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

630626:EBL RS09480
gene id: 630626:EBL_RS09480
uniprot id: I2B951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

630626:EBL RS08920
gene id: 630626:EBL_RS08920
uniprot id: I2B8T7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

630626:EBL RS15560
gene id: 630626:EBL_RS15560
uniprot id: I2BCM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

630626:EBL RS14065
gene id: 630626:EBL_RS14065
uniprot id: I2BBS4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

630626:EBL RS18465
gene id: 630626:EBL_RS18465
uniprot id: I2BE93
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS15870
gene id: 630626:EBL_RS15870
uniprot id: I2BCT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS14315
gene id: 630626:EBL_RS14315
uniprot id: I2BBX4
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

630626:EBL RS06810
gene id: 630626:EBL_RS06810
uniprot id: I2B7L4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS02570
gene id: 630626:EBL_RS02570
uniprot id: I2B557
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

630626:EBL RS13055
gene id: 630626:EBL_RS13055
uniprot id: I2BB75
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

630626:EBL RS15465
gene id: 630626:EBL_RS15465
uniprot id: I2BCK7
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

630626:EBL RS08250
gene id: 630626:EBL_RS08250
uniprot id: I2B8F4
names: Subcellular Location Annotation
messages: target cell cytoplasm

630626:EBL RS13560
gene id: 630626:EBL_RS13560
uniprot id: I2BBH1
names: Similarity
messages: Belongs to the UPF0597 family.

630626:EBL RS07075
gene id: 630626:EBL_RS07075
uniprot id: I2B7R7
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

630626:EBL RS07550
gene id: 630626:EBL_RS07550
uniprot id: I2B808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

630626:EBL RS13245
gene id: 630626:EBL_RS13245
uniprot id: I2BBA5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

630626:EBL RS16350
gene id: 630626:EBL_RS16350
uniprot id: I2BD36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

630626:EBL RS02030
gene id: 630626:EBL_RS02030
uniprot id: I2B4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

630626:EBL RS07450
gene id: 630626:EBL_RS07450
uniprot id: I2B7Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

630626:EBL RS06535
gene id: 630626:EBL_RS06535
uniprot id: I2B7F9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

630626:EBL RS05970
gene id: 630626:EBL_RS05970
uniprot id: I2B744
names: Similarity
messages: Belongs to the Nudix hydrolase family.

630626:EBL RS09645
gene id: 630626:EBL_RS09645
uniprot id: I2B983
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS10800
gene id: 630626:EBL_RS10800
uniprot id: I2B9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

630626:EBL RS11330
gene id: 630626:EBL_RS11330
uniprot id: I2BA81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

630626:EBL RS13115
gene id: 630626:EBL_RS13115
uniprot id: I2BB79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS10325
gene id: 630626:EBL_RS10325
uniprot id: I2B9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

630626:EBL RS13230
gene id: 630626:EBL_RS13230
uniprot id: I2BBA2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

630626:EBL RS03590
gene id: 630626:EBL_RS03590
uniprot id: I2B5S0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

630626:EBL RS13405
gene id: 630626:EBL_RS13405
uniprot id: I2BBE1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

630626:EBL RS13015
gene id: 630626:EBL_RS13015
uniprot id: I2BB67
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

630626:EBL RS19330
gene id: 630626:EBL_RS19330
uniprot id: I2BER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

630626:EBL RS16000
gene id: 630626:EBL_RS16000
uniprot id: I2BCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with KefC.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.

630626:EBL RS07195
gene id: 630626:EBL_RS07195
uniprot id: I2B7U1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

630626:EBL RS01635
gene id: 630626:EBL_RS01635
uniprot id: I2B4L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

630626:EBL RS19010
gene id: 630626:EBL_RS19010
uniprot id: I2BEJ9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

630626:EBL RS12335
gene id: 630626:EBL_RS12335
uniprot id: I2BAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

630626:EBL RS17285
gene id: 630626:EBL_RS17285
uniprot id: I2BDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

630626:EBL RS08890
gene id: 630626:EBL_RS08890
uniprot id: I2B8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

630626:EBL RS11970
gene id: 630626:EBL_RS11970
uniprot id: I2BAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

630626:EBL RS19980
gene id: 630626:EBL_RS19980
uniprot id: I2BAE6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

630626:EBL RS03535
gene id: 630626:EBL_RS03535
uniprot id: I2B5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS04960
gene id: 630626:EBL_RS04960
uniprot id: I2B6J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

630626:EBL RS11160
gene id: 630626:EBL_RS11160
uniprot id: I2BA46
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

630626:EBL RS17700
gene id: 630626:EBL_RS17700
uniprot id: I2BDV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

630626:EBL RS05085
gene id: 630626:EBL_RS05085
uniprot id: I2B6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

630626:EBL RS06500
gene id: 630626:EBL_RS06500
uniprot id: I2B7F2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS08455
gene id: 630626:EBL_RS08455
uniprot id: I2B8J2
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

630626:EBL RS01410
gene id: 630626:EBL_RS01410
uniprot id: I2B4H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

630626:EBL RS15415
gene id: 630626:EBL_RS15415
uniprot id: I2BCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

630626:EBL RS15760
gene id: 630626:EBL_RS15760
uniprot id: I2BCR7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

630626:EBL RS18615
gene id: 630626:EBL_RS18615
uniprot id: I2BEB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

630626:EBL RS15100
gene id: 630626:EBL_RS15100
uniprot id: I2BCD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

630626:EBL RS03730
gene id: 630626:EBL_RS03730
uniprot id: I2B5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

630626:EBL RS12125
gene id: 630626:EBL_RS12125
uniprot id: I2BAP0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

630626:EBL RS17750
gene id: 630626:EBL_RS17750
uniprot id: I2BDW3
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

630626:EBL RS08765
gene id: 630626:EBL_RS08765
uniprot id: I2B8Q6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

630626:EBL RS01595
gene id: 630626:EBL_RS01595
uniprot id: I2B4K5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS04870
gene id: 630626:EBL_RS04870
uniprot id: I2B6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0257 family.
messages: Cell membrane

630626:EBL RS02895
gene id: 630626:EBL_RS02895
uniprot id: I2B5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell inner membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

630626:EBL RS00295
gene id: 630626:EBL_RS00295
uniprot id: I2B3U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

630626:EBL RS19385
gene id: 630626:EBL_RS19385
uniprot id: I2BES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS02080
gene id: 630626:EBL_RS02080
uniprot id: I2B4V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

630626:EBL RS07515
gene id: 630626:EBL_RS07515
uniprot id: I2B800
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS18260
gene id: 630626:EBL_RS18260
uniprot id: I2BE55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

630626:EBL RS17885
gene id: 630626:EBL_RS17885
uniprot id: I2BDZ1
names: Cofactor
messages: Can also use Mn(2+) ion.

630626:EBL RS11765
gene id: 630626:EBL_RS11765
uniprot id: I2BAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS19045
gene id: 630626:EBL_RS19045
uniprot id: I2BEK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS17840
gene id: 630626:EBL_RS17840
uniprot id: I2BDY2
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS13170
gene id: 630626:EBL_RS13170
uniprot id: I2BB90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

630626:EBL RS02075
gene id: 630626:EBL_RS02075
uniprot id: I2B4V1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

630626:EBL RS18750
gene id: 630626:EBL_RS18750
uniprot id: I2BEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

630626:EBL RS17315
gene id: 630626:EBL_RS17315
uniprot id: I2BDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

630626:EBL RS07520
gene id: 630626:EBL_RS07520
uniprot id: I2B801
names: Similarity
messages: Belongs to the LacAB/RpiB family.

630626:EBL RS07080
gene id: 630626:EBL_RS07080
uniprot id: I2B7R8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

630626:EBL RS00595
gene id: 630626:EBL_RS00595
uniprot id: I2B407
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS07125
gene id: 630626:EBL_RS07125
uniprot id: I2B7S7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

630626:EBL RS15770
gene id: 630626:EBL_RS15770
uniprot id: I2BCR9
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

630626:EBL RS18645
gene id: 630626:EBL_RS18645
uniprot id: I2BEC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

630626:EBL RS09030
gene id: 630626:EBL_RS09030
uniprot id: I2B8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

630626:EBL RS15960
gene id: 630626:EBL_RS15960
uniprot id: I2BCV7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

630626:EBL RS12330
gene id: 630626:EBL_RS12330
uniprot id: I2BAT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

630626:EBL RS11510
gene id: 630626:EBL_RS11510
uniprot id: I2BAB8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

630626:EBL RS06540
gene id: 630626:EBL_RS06540
uniprot id: I2B7G0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS17325
gene id: 630626:EBL_RS17325
uniprot id: I2BDM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

630626:EBL RS09305
gene id: 630626:EBL_RS09305
uniprot id: I2B914
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

630626:EBL RS02825
gene id: 630626:EBL_RS02825
uniprot id: I2B5B0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS18145
gene id: 630626:EBL_RS18145
uniprot id: I2BE32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

630626:EBL RS01160
gene id: 630626:EBL_RS01160
uniprot id: I2B4C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

630626:EBL RS16445
gene id: 630626:EBL_RS16445
uniprot id: I2BD53
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

630626:EBL RS14100
gene id: 630626:EBL_RS14100
uniprot id: I2BBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

630626:EBL RS12130
gene id: 630626:EBL_RS12130
uniprot id: I2BAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

630626:EBL RS12175
gene id: 630626:EBL_RS12175
uniprot id: I2BAQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

630626:EBL RS02180
gene id: 630626:EBL_RS02180
uniprot id: I2B4X2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS08800
gene id: 630626:EBL_RS08800
uniprot id: I2B8R3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

630626:EBL RS11060
gene id: 630626:EBL_RS11060
uniprot id: I2BA28
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

630626:EBL RS11195
gene id: 630626:EBL_RS11195
uniprot id: I2BA53
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

630626:EBL RS03205
gene id: 630626:EBL_RS03205
uniprot id: I2B5I9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

630626:EBL RS09220
gene id: 630626:EBL_RS09220
uniprot id: I2B8Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS03945
gene id: 630626:EBL_RS03945
uniprot id: I2B5Z1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

630626:EBL RS05270
gene id: 630626:EBL_RS05270
uniprot id: I2B6Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS08500
gene id: 630626:EBL_RS08500
uniprot id: I2B8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

630626:EBL RS13945
gene id: 630626:EBL_RS13945
uniprot id: I2BBP9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

630626:EBL RS11180
gene id: 630626:EBL_RS11180
uniprot id: I2BA50
names: Similarity
messages: Belongs to the pyruvate kinase family.

630626:EBL RS01365
gene id: 630626:EBL_RS01365
uniprot id: I2B4G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

630626:EBL RS13805
gene id: 630626:EBL_RS13805
uniprot id: I2BBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

630626:EBL RS07200
gene id: 630626:EBL_RS07200
uniprot id: I2B7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

630626:EBL RS16535
gene id: 630626:EBL_RS16535
uniprot id: I2BD71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

630626:EBL RS16600
gene id: 630626:EBL_RS16600
uniprot id: I2BD84
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

630626:EBL RS07800
gene id: 630626:EBL_RS07800
uniprot id: I2B858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

630626:EBL RS06615
gene id: 630626:EBL_RS06615
uniprot id: I2B7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

630626:EBL RS02860
gene id: 630626:EBL_RS02860
uniprot id: I2B5B7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

630626:EBL RS16080
gene id: 630626:EBL_RS16080
uniprot id: I2BCY1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

630626:EBL RS00825
gene id: 630626:EBL_RS00825
uniprot id: I2B453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS06170
gene id: 630626:EBL_RS06170
uniprot id: I2B785
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

630626:EBL RS03500
gene id: 630626:EBL_RS03500
uniprot id: I2B5Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

630626:EBL RS13320
gene id: 630626:EBL_RS13320
uniprot id: I2BBC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

630626:EBL RS08450
gene id: 630626:EBL_RS08450
uniprot id: I2B8J1
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS05260
gene id: 630626:EBL_RS05260
uniprot id: I2B6Q7
names: Subcellular Location Annotation
messages: Cytoplasm

630626:EBL RS05890
gene id: 630626:EBL_RS05890
uniprot id: I2B728
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS14280
gene id: 630626:EBL_RS14280
uniprot id: I2BBW7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06085
gene id: 630626:EBL_RS06085
uniprot id: I2B768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

630626:EBL RS15950
gene id: 630626:EBL_RS15950
uniprot id: I2BCV5
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

630626:EBL RS02135
gene id: 630626:EBL_RS02135
uniprot id: I2B4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

630626:EBL RS12150
gene id: 630626:EBL_RS12150
uniprot id: I2BAP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

630626:EBL RS07980
gene id: 630626:EBL_RS07980
uniprot id: I2B894
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

630626:EBL RS03480
gene id: 630626:EBL_RS03480
uniprot id: I2B5P8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

630626:EBL RS11255
gene id: 630626:EBL_RS11255
uniprot id: I2BA65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

630626:EBL RS00585
gene id: 630626:EBL_RS00585
uniprot id: I2B405
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

630626:EBL RS11445
gene id: 630626:EBL_RS11445
uniprot id: I2BAA5
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

630626:EBL RS13650
gene id: 630626:EBL_RS13650
uniprot id: I2BBI9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

630626:EBL RS06095
gene id: 630626:EBL_RS06095
uniprot id: I2B770
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

630626:EBL RS17810
gene id: 630626:EBL_RS17810
uniprot id: I2BDX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

630626:EBL RS11625
gene id: 630626:EBL_RS11625
uniprot id: I2BAE1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

630626:EBL RS17705
gene id: 630626:EBL_RS17705
uniprot id: I2BDV3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS18790
gene id: 630626:EBL_RS18790
uniprot id: I2BEF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

630626:EBL RS09450
gene id: 630626:EBL_RS09450
uniprot id: I2B945
names: Similarity
messages: Belongs to the DapA family.

630626:EBL RS18960
gene id: 630626:EBL_RS18960
uniprot id: I2BEI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

630626:EBL RS17950
gene id: 630626:EBL_RS17950
uniprot id: I2BE00
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

630626:EBL RS15985
gene id: 630626:EBL_RS15985
uniprot id: I2BCW2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

630626:EBL RS12665
gene id: 630626:EBL_RS12665
uniprot id: I2BB00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS01835
gene id: 630626:EBL_RS01835
uniprot id: I2B4Q4
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

630626:EBL RS01825
gene id: 630626:EBL_RS01825
uniprot id: I2B4Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

630626:EBL RS12160
gene id: 630626:EBL_RS12160
uniprot id: I2BAP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

630626:EBL RS06290
gene id: 630626:EBL_RS06290
uniprot id: I2B7B1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

630626:EBL RS05205
gene id: 630626:EBL_RS05205
uniprot id: I2B6P6
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

630626:EBL RS05945
gene id: 630626:EBL_RS05945
uniprot id: I2B739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS01615
gene id: 630626:EBL_RS01615
uniprot id: I2B4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

630626:EBL RS12895
gene id: 630626:EBL_RS12895
uniprot id: I2BB43
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

630626:EBL RS08645
gene id: 630626:EBL_RS08645
uniprot id: I2B8N1
names: Similarity
messages: Belongs to the peptidase S66 family.

630626:EBL RS07970
gene id: 630626:EBL_RS07970
uniprot id: I2B892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS01250
gene id: 630626:EBL_RS01250
uniprot id: I2B4E3
names: Similarity
messages: Belongs to the UPF0270 family.

630626:EBL RS14225
gene id: 630626:EBL_RS14225
uniprot id: I2BBV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

630626:EBL RS06745
gene id: 630626:EBL_RS06745
uniprot id: I2B7K1
names: Similarity
messages: Belongs to the universal stress protein A family.

630626:EBL RS05435
gene id: 630626:EBL_RS05435
uniprot id: I2B6T7
names: Similarity
messages: Belongs to the universal stress protein A family.

630626:EBL RS04150
gene id: 630626:EBL_RS04150
uniprot id: I2B634
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

630626:EBL RS12850
gene id: 630626:EBL_RS12850
uniprot id: I2BB33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

630626:EBL RS10710
gene id: 630626:EBL_RS10710
uniprot id: I2B9V6
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

630626:EBL RS18435
gene id: 630626:EBL_RS18435
uniprot id: I2BE87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

630626:EBL RS09585
gene id: 630626:EBL_RS09585
uniprot id: I2B971
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

630626:EBL RS15810
gene id: 630626:EBL_RS15810
uniprot id: I2BCS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

630626:EBL RS14760
gene id: 630626:EBL_RS14760
uniprot id: I2BC67
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

630626:EBL RS18965
gene id: 630626:EBL_RS18965
uniprot id: I2BEI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

630626:EBL RS03940
gene id: 630626:EBL_RS03940
uniprot id: I2B5Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

630626:EBL RS17080
gene id: 630626:EBL_RS17080
uniprot id: I2BDH7
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS03155
gene id: 630626:EBL_RS03155
uniprot id: I2B5H9
names: Function
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

630626:EBL RS03215
gene id: 630626:EBL_RS03215
uniprot id: I2B5J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

630626:EBL RS08085
gene id: 630626:EBL_RS08085
uniprot id: I2B8B6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

630626:EBL RS03965
gene id: 630626:EBL_RS03965
uniprot id: I2B5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS07265
gene id: 630626:EBL_RS07265
uniprot id: I2B7V5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

630626:EBL RS14620
gene id: 630626:EBL_RS14620
uniprot id: I2BC38
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

630626:EBL RS14045
gene id: 630626:EBL_RS14045
uniprot id: I2BBS0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

630626:EBL RS02145
gene id: 630626:EBL_RS02145
uniprot id: I2B4W5
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

630626:EBL RS11760
gene id: 630626:EBL_RS11760
uniprot id: I2BAG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

630626:EBL RS18265
gene id: 630626:EBL_RS18265
uniprot id: I2BE56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

630626:EBL RS04900
gene id: 630626:EBL_RS04900
uniprot id: I2B6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

630626:EBL RS01720
gene id: 630626:EBL_RS01720
uniprot id: I2B4N0
names: Similarity
messages: Belongs to the peptidase S1C family.

630626:EBL RS04380
gene id: 630626:EBL_RS04380
uniprot id: I2B677
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

630626:EBL RS00375
gene id: 630626:EBL_RS00375
uniprot id: I2B3W3
names: Function
names: Similarity
messages: Belongs to the rhamnulokinase family.
messages: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.

630626:EBL RS15385
gene id: 630626:EBL_RS15385
uniprot id: I2BCJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

630626:EBL RS18370
gene id: 630626:EBL_RS18370
uniprot id: I2BE74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

630626:EBL RS01390
gene id: 630626:EBL_RS01390
uniprot id: I2B4H0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

630626:EBL RS04770
gene id: 630626:EBL_RS04770
uniprot id: I2B6F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

630626:EBL RS07460
gene id: 630626:EBL_RS07460
uniprot id: I2B7Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

630626:EBL RS14005
gene id: 630626:EBL_RS14005
uniprot id: I2BBR2
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS06195
gene id: 630626:EBL_RS06195
uniprot id: I2B790
names: Similarity
messages: Belongs to the catalase family.

630626:EBL RS05105
gene id: 630626:EBL_RS05105
uniprot id: I2B6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

630626:EBL RS07370
gene id: 630626:EBL_RS07370
uniprot id: I2B7X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

630626:EBL RS02275
gene id: 630626:EBL_RS02275
uniprot id: I2B4Z1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

630626:EBL RS13880
gene id: 630626:EBL_RS13880
uniprot id: I2BBN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS03130
gene id: 630626:EBL_RS03130
uniprot id: I2B5H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

630626:EBL RS15035
gene id: 630626:EBL_RS15035
uniprot id: I2BCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

630626:EBL RS00995
gene id: 630626:EBL_RS00995
uniprot id: I2B488
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

630626:EBL RS09465
gene id: 630626:EBL_RS09465
uniprot id: I2B948
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

630626:EBL RS04780
gene id: 630626:EBL_RS04780
uniprot id: K6USI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

630626:EBL RS13595
gene id: 630626:EBL_RS13595
uniprot id: I2BBH8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

630626:EBL RS11070
gene id: 630626:EBL_RS11070
uniprot id: I2BA30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

630626:EBL RS01925
gene id: 630626:EBL_RS01925
uniprot id: I2B4S2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

630626:EBL RS03865
gene id: 630626:EBL_RS03865
uniprot id: I2B5X7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

630626:EBL RS03470
gene id: 630626:EBL_RS03470
uniprot id: I2B5P5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

630626:EBL RS03710
gene id: 630626:EBL_RS03710
uniprot id: I2B5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

630626:EBL RS17725
gene id: 630626:EBL_RS17725
uniprot id: I2BDV8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

630626:EBL RS11515
gene id: 630626:EBL_RS11515
uniprot id: I2BAB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

630626:EBL RS18120
gene id: 630626:EBL_RS18120
uniprot id: I2BE27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

630626:EBL RS04110
gene id: 630626:EBL_RS04110
uniprot id: I2B626
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS04925
gene id: 630626:EBL_RS04925
uniprot id: I2B6I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

630626:EBL RS12860
gene id: 630626:EBL_RS12860
uniprot id: I2BB35
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

630626:EBL RS12620
gene id: 630626:EBL_RS12620
uniprot id: I2BAZ0
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS17865
gene id: 630626:EBL_RS17865
uniprot id: I2BDY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

630626:EBL RS13220
gene id: 630626:EBL_RS13220
uniprot id: I2BBA0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

630626:EBL RS11470
gene id: 630626:EBL_RS11470
uniprot id: I2BAB0
names: Subcellular Location Annotation
messages: Cell inner membrane

630626:EBL RS03295
gene id: 630626:EBL_RS03295
uniprot id: I2B5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

630626:EBL RS00970
gene id: 630626:EBL_RS00970
uniprot id: I2B483
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

630626:EBL RS05390
gene id: 630626:EBL_RS05390
uniprot id: I2B6S8
names: Subcellular Location Annotation
messages: Membrane

630626:EBL RS09285
gene id: 630626:EBL_RS09285
uniprot id: I2B910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

630626:EBL RS15185
gene id: 630626:EBL_RS15185
uniprot id: I2BCF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

630626:EBL RS11225
gene id: 630626:EBL_RS11225
uniprot id: I2BA59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

630626:EBL RS11850
gene id: 630626:EBL_RS11850
uniprot id: I2BAI5
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

630626:EBL RS05070
gene id: 630626:EBL_RS05070
uniprot id: I2B6L6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

630626:EBL RS15510
gene id: 630626:EBL_RS15510
uniprot id: I2BCL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

630626:EBL RS05155
gene id: 630626:EBL_RS05155
uniprot id: I2B6N5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

630626:EBL RS04100
gene id: 630626:EBL_RS04100
uniprot id: I2B624
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

630626:EBL RS13820
gene id: 630626:EBL_RS13820
uniprot id: I2BBM2
names: Subcellular Location Annotation
messages: Cell inner membrane