6238:CBG 02988
gene id: 6238:CBG_02988
uniprot id: A8WT17
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 18020
gene id: 6238:CBG_18020
uniprot id: A8XSU5
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 09727
gene id: 6238:CBG_09727
uniprot id: A8X8E6
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 10036
gene id: 6238:CBG_10036
uniprot id: Q61IX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity).
messages: Nucleus

6238:CBG 09566
gene id: 6238:CBG_09566
uniprot id: A8X8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

6238:CBG 18006
gene id: 6238:CBG_18006
uniprot id: A8XST2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

6238:CBG 06776
gene id: 6238:CBG_06776
uniprot id: A8X319
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

6238:CBG 18155
gene id: 6238:CBG_18155
uniprot id: A8XT52
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 21822
gene id: 6238:CBG_21822
uniprot id: A8Y0W5
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 02872
gene id: 6238:CBG_02872
uniprot id: A8WTB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

6238:CBG 09255
gene id: 6238:CBG_09255
uniprot id: A8X9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

6238:CBG 24154
gene id: 6238:CBG_24154
uniprot id: A8WK35
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

6238:CBG 15314
gene id: 6238:CBG_15314
uniprot id: A8XLX2
names: Similarity
messages: Belongs to the CD36 family.

6238:CBG 03716
gene id: 6238:CBG_03716
uniprot id: A8WWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

6238:CBG 17083
gene id: 6238:CBG_17083
uniprot id: A8XQF2
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 01233
gene id: 6238:CBG_01233
uniprot id: A8WPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 08259
gene id: 6238:CBG_08259
uniprot id: A8X658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 07939
gene id: 6238:CBG_07939
uniprot id: A8X5E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

6238:CBG 05470
gene id: 6238:CBG_05470
uniprot id: A8WZY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

6238:CBG 00969
gene id: 6238:CBG_00969
uniprot id: A8WP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.
messages: Cytoplasm

6238:CBG 06792
gene id: 6238:CBG_06792
uniprot id: A8X331
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01213
gene id: 6238:CBG_01213
uniprot id: A8WPU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 23216
gene id: 6238:CBG_23216
uniprot id: A8Y4F7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 18154
gene id: 6238:CBG_18154
uniprot id: A8XT51
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09245
gene id: 6238:CBG_09245
uniprot id: A8X9J4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 19536
gene id: 6238:CBG_19536
uniprot id: A8XVU6
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 06286
gene id: 6238:CBG_06286
uniprot id: A8X1V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
messages: Secreted

6238:CBG 16828
gene id: 6238:CBG_16828
uniprot id: G2J6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

6238:CBG 15299
gene id: 6238:CBG_15299
uniprot id: A8XLW1
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

6238:CBG 04366
gene id: 6238:CBG_04366
uniprot id: A8WXD4
names: Similarity
messages: Belongs to the profilin family.

6238:CBG 17708
gene id: 6238:CBG_17708
uniprot id: A8XRH0
names: Similarity
messages: Belongs to the learning-associated protein family.

6238:CBG 17914
gene id: 6238:CBG_17914
uniprot id: A8XS35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 22982
gene id: 6238:CBG_22982
uniprot id: A8Y3I5
names: Similarity
messages: Belongs to the peptidase S28 family.

6238:CBG 05068
gene id: 6238:CBG_05068
uniprot id: A8WZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

6238:CBG 19981
gene id: 6238:CBG_19981
uniprot id: A8XWV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 08826
gene id: 6238:CBG_08826
uniprot id: Q61LN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

6238:CBG 06915
gene id: 6238:CBG_06915
uniprot id: A8X3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

6238:CBG 05744
gene id: 6238:CBG_05744
uniprot id: A8X1R0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

6238:CBG 22149
gene id: 6238:CBG_22149
uniprot id: A8Y1N2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 00525
gene id: 6238:CBG_00525
uniprot id: A8WNP5
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 24700
gene id: 6238:CBG_24700
uniprot id: A8WLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion
messages: Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins.

6238:CBG 12722
gene id: 6238:CBG_12722
uniprot id: A8XGF2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 16182
gene id: 6238:CBG_16182
uniprot id: Q613V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. May play a role in resistance to fungal infection in the epidermis by regulating the up-regulation of several antimicrobial peptides of the NLP and CNC families. Upstream of plc-3, egl-8, tpa-1 and the p38-like pathway, required for the expression of antimicrobial peptide nlp-29 in the epidermis in response to fungal infection or physical injury.

6238:CBG 17980
gene id: 6238:CBG_17980
uniprot id: A8XSQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Caudal homeobox family.
messages: Chromosome
messages: Interacts with tir-1 and let-756.
messages: Nucleus
messages: Transcriptional activator. Interacts with promoter regions for tbx-8.9, tbx-9, elt-1, hnd-1, scrt-1, and vab-7 genes. Binds the sequence ATTTATGAC. Binds to the enhancer region of the hlh-1 gene promoter during embryonic body wall muscle development. Activates the gene for mab-5 in embryo development. Necessary for vab-7 expression in C blastomeres in the posterior of embryos. Required for posterior V6 neuroectoblast cell fate specification during postembryonic neurogenesis (patterning) which generates the characteristic ray lineage during male tail development. Binds to ced-3 promoter and activated expression which is crucial for tail-spike cell death. Has a role in E cell specification in endoderm development and body wall muscle development (By similarity).
messages: kinetochore

6238:CBG 08843
gene id: 6238:CBG_08843
uniprot id: A8X7I6
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 00686
gene id: 6238:CBG_00686
uniprot id: A8WNA6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05894
gene id: 6238:CBG_05894
uniprot id: A8X1E2
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

6238:CBG 12712
gene id: 6238:CBG_12712
uniprot id: A8XGE3
names: Similarity
messages: Belongs to the paraoxonase family.

6238:CBG 24164
gene id: 6238:CBG_24164
uniprot id: A8WK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

6238:CBG 23445
gene id: 6238:CBG_23445
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 08086
gene id: 6238:CBG_08086
uniprot id: A8X5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

6238:CBG 20782
gene id: 6238:CBG_20782
uniprot id: E3CU82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
messages: Cytoplasm
messages: Nucleus

6238:CBG 16384
gene id: 6238:CBG_16384
uniprot id: A8XNJ8
names: Similarity
messages: Belongs to the intermediate filament family.

6238:CBG 07412
gene id: 6238:CBG_07412
uniprot id: A8X4U1
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 02552
gene id: 6238:CBG_02552
uniprot id: A8WU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 18147
gene id: 6238:CBG_18147
uniprot id: A8XT45
names: Similarity
messages: Belongs to the peptidase M17 family.

6238:CBG 02476
gene id: 6238:CBG_02476
uniprot id: A8WU84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: FMRFamides and FMRFamide-like peptides are neuropeptides.
messages: Secreted

6238:CBG 21896
gene id: 6238:CBG_21896
uniprot id: A8Y124
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 04517
gene id: 6238:CBG_04517
uniprot id: A8WXP7
names: Similarity
messages: Belongs to the TPD52 family.

6238:CBG 08546
gene id: 6238:CBG_08546
uniprot id: Q9GNN7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Participates in the inductive signaling pathway downstream of let-60 Ras and the RAF/MAP kinase cascade to regulate specification and differentiation of many cell types. Positively regulates the fate of vulval precursor cells. Required for induction of the P12 and excretory duct cell fates. In males, it is also required for proper formation of spicules. Does not function in the signaling pathway that promotes exit from pachytene (By similarity).

6238:CBG 04179
gene id: 6238:CBG_04179
uniprot id: A8WWC8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 00562
gene id: 6238:CBG_00562
uniprot id: A8WNK9
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19300
gene id: 6238:CBG_19300
uniprot id: A8XVA8
names: Similarity
messages: Belongs to the mTERF family.

6238:CBG 10981
gene id: 6238:CBG_10981
uniprot id: A8XBZ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

6238:CBG 23917
gene id: 6238:CBG_23917
uniprot id: A8WJK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 13279
gene id: 6238:CBG_13279
uniprot id: A8XHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

6238:CBG 22842
gene id: 6238:CBG_22842
uniprot id: A8Y366
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 20783
gene id: 6238:CBG_20783
uniprot id: A8XYL7
names: Similarity
messages: Belongs to the SUA5 family.

6238:CBG 20787
gene id: 6238:CBG_20787
uniprot id: A8XYM1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

6238:CBG 13376
gene id: 6238:CBG_13376
uniprot id: A8XHX0
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

6238:CBG 05791
gene id: 6238:CBG_05791
uniprot id: A8X1M2
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 00794
gene id: 6238:CBG_00794
uniprot id: A8WNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

6238:CBG 19302
gene id: 6238:CBG_19302
uniprot id: A8XVB0
names: Similarity
messages: Belongs to the MAD1 family.

6238:CBG 14876
gene id: 6238:CBG_14876
uniprot id: A8XKW4
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 18291
gene id: 6238:CBG_18291
uniprot id: Q17297
names: Domain
names: Function
names: Similarity
messages: Adopts an immunoglobulin-like beta-sandwich fold forming a hydrophobic cavity that capture N-terminally myristoylated target peptides. Phe residues within the hydrophobic beta sandwich are required for myristate binding (By similarity).
messages: Belongs to the PDE6D/unc-119 family.
messages: Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system (By similarity).

6238:CBG 21922
gene id: 6238:CBG_21922
uniprot id: Q60Q85
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Homotetramer.
messages: Nucleus

6238:CBG 20564
gene id: 6238:CBG_20564
uniprot id: A8XY34
names: Similarity
messages: Belongs to the MEMO1 family.

6238:CBG 18329
gene id: 6238:CBG_18329
uniprot id: A8XSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

6238:CBG 02466
gene id: 6238:CBG_02466
uniprot id: A8WU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

6238:CBG 05752
gene id: 6238:CBG_05752
uniprot id: Q61TH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of tim-9/tin-9.1 and 3 copies of tim-10/tin-10, named soluble 70 kDa complex. The complex associates with the tim-22 component of the TIM22 complex. Interacts with multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of tim-9/tin-9.1 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

6238:CBG 09676
gene id: 6238:CBG_09676
uniprot id: Q61JR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation (By similarity).

6238:CBG 19425
gene id: 6238:CBG_19425
uniprot id: A8XVL0
names: Similarity
messages: Belongs to the MYG1 family.

6238:CBG 22906
gene id: 6238:CBG_22906
uniprot id: A8Y3C0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17088
gene id: 6238:CBG_17088
uniprot id: A8XQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 24744
gene id: 6238:CBG_24744
uniprot id: A8WLD7
names: Similarity
messages: Belongs to the nanos family.

6238:CBG 01620
gene id: 6238:CBG_01620
uniprot id: A8WR83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 02128
gene id: 6238:CBG_02128
uniprot id: A8WS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 17638
gene id: 6238:CBG_17638
uniprot id: A8XRM8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02743
gene id: 6238:CBG_02743
uniprot id: A8WTL7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 09961
gene id: 6238:CBG_09961
uniprot id: A8XA19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

6238:CBG 21324
gene id: 6238:CBG_21324
uniprot id: A8XZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

6238:CBG 03993
gene id: 6238:CBG_03993
uniprot id: A8WVY0
names: Subcellular Location Annotation
messages: nucleolus

6238:CBG 09591
gene id: 6238:CBG_09591
uniprot id: A8X8Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

6238:CBG 01307
gene id: 6238:CBG_01307
uniprot id: A8WQ37
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 04588
gene id: 6238:CBG_04588
uniprot id: A8WY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

6238:CBG 19427
gene id: 6238:CBG_19427
uniprot id: A8XVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

6238:CBG 23264
gene id: 6238:CBG_23264
uniprot id: A8Y4B7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family.
messages: Belongs to the nematode receptor-like protein sre family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 12253
gene id: 6238:CBG_12253
uniprot id: Q61E22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UFM1 family.
messages: Interacts with odr-8; leading to deufmylation.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (By similarity). The so-called ufmylation requires the ufm-1-activating E1 enzyme uba-5, the ufm-1-conjugating E2 enzyme ufc-1, and probably the ufm-1-ligase E3 enzyme ufl-1 (By similarity).

6238:CBG 18134
gene id: 6238:CBG_18134
uniprot id: A8XT34
names: Similarity
messages: Belongs to the DDRGK1 family.

6238:CBG 21354
gene id: 6238:CBG_21354
uniprot id: A8XZX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 06111
gene id: 6238:CBG_06111
uniprot id: A8X0V7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

6238:CBG 21068
gene id: 6238:CBG_21068
uniprot id: A8XZ98
names: Subcellular Location Annotation
messages: Cytoplasm

6238:CBG 03293
gene id: 6238:CBG_03293
uniprot id: A8WSD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

6238:CBG 09821
gene id: 6238:CBG_09821
uniprot id: A8X9Q6
names: Similarity
messages: Belongs to the TBCC family.

6238:CBG 12802
gene id: 6238:CBG_12802
uniprot id: A8XFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

6238:CBG 03161
gene id: 6238:CBG_03161
uniprot id: A8WSN1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 13547
gene id: 6238:CBG_13547
uniprot id: A8XI57
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

6238:CBG 01476
gene id: 6238:CBG_01476
uniprot id: A8WQL4
names: Similarity
messages: Belongs to the SNF7 family.

6238:CBG 08993
gene id: 6238:CBG_08993
uniprot id: A8X823
names: Similarity
messages: Belongs to the RCAN family.

6238:CBG 11502
gene id: 6238:CBG_11502
uniprot id: A8XCU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

6238:CBG 08266
gene id: 6238:CBG_08266
uniprot id: A8X663
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

6238:CBG 05065
gene id: 6238:CBG_05065
uniprot id: A8WZ34
names: Similarity
messages: Belongs to the FAH family.

6238:CBG 10416
gene id: 6238:CBG_10416
uniprot id: A8XB57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 18597
gene id: 6238:CBG_18597
uniprot id: A8XTN8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 12252
gene id: 6238:CBG_12252
uniprot id: A8XF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

6238:CBG 08858
gene id: 6238:CBG_08858
uniprot id: A8X7K1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 12818
gene id: 6238:CBG_12818
uniprot id: A8XFP3
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

6238:CBG 12053
gene id: 6238:CBG_12053
uniprot id: A8XEF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 08274
gene id: 6238:CBG_08274
uniprot id: A8X670
names: Similarity
messages: Belongs to the PDCD5 family.

6238:CBG 09077
gene id: 6238:CBG_09077
uniprot id: Q61L47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for activated transcription of the MtnA, MtnB and MtnD genes.
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 08569
gene id: 6238:CBG_08569
uniprot id: A8X739
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

6238:CBG 01247
gene id: 6238:CBG_01247
uniprot id: A8WPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 01589
gene id: 6238:CBG_01589
uniprot id: A8WRA9
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

6238:CBG 01246
gene id: 6238:CBG_01246
uniprot id: A8WPY0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 00433
gene id: 6238:CBG_00433
uniprot id: A8WN29
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 06668
gene id: 6238:CBG_06668
uniprot id: A8X2T5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

6238:CBG 08414
gene id: 6238:CBG_08414
uniprot id: A8X6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

6238:CBG 05730
gene id: 6238:CBG_05730
uniprot id: E3CTZ1
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 12415
gene id: 6238:CBG_12415
uniprot id: A8XFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

6238:CBG 00143
gene id: 6238:CBG_00143
uniprot id: A8WMD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

6238:CBG 23282
gene id: 6238:CBG_23282
uniprot id: A8Y4A1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02932
gene id: 6238:CBG_02932
uniprot id: A8WT67
names: Similarity
messages: Belongs to the GTR/RAG GTP-binding protein family.

6238:CBG 17894
gene id: 6238:CBG_17894
uniprot id: A8XS17
names: Caution
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Metalloprotease.
messages: Secreted

6238:CBG 01016
gene id: 6238:CBG_01016
uniprot id: A8WP37
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 01439
gene id: 6238:CBG_01439
uniprot id: A8WQF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 02625
gene id: 6238:CBG_02625
uniprot id: Q620W3
names: Similarity
messages: Belongs to the EFR3 family.

6238:CBG 14167
gene id: 6238:CBG_14167
uniprot id: A8XJF8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

6238:CBG 06960
gene id: 6238:CBG_06960
uniprot id: A8X418
names: Similarity
messages: Belongs to the NPL4 family.

6238:CBG 14138
gene id: 6238:CBG_14138
uniprot id: A8XJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Mitochondrion
messages: Thought to be a regulatory component of the ATP-synthesizing complex in the mitochondria.

6238:CBG 09177
gene id: 6238:CBG_09177
uniprot id: A8X887
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 23444
gene id: 6238:CBG_23444
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 04604
gene id: 6238:CBG_04604
uniprot id: A8WY14
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 00567
gene id: 6238:CBG_00567
uniprot id: A8WNK5
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

6238:CBG 13978
gene id: 6238:CBG_13978
uniprot id: A8XIW7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.

6238:CBG 02394
gene id: 6238:CBG_02394
uniprot id: Q621Q3
names: Function
messages: Required maternally for early embryonic cell divisions. May have a role in DNA replication.

6238:CBG 17822
gene id: 6238:CBG_17822
uniprot id: A8XRU8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 17672
gene id: 6238:CBG_17672
uniprot id: A8XRJ9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05572
gene id: 6238:CBG_05572
uniprot id: A8X064
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

6238:CBG 13195
gene id: 6238:CBG_13195
uniprot id: Q1M2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

6238:CBG 20369
gene id: 6238:CBG_20369
uniprot id: A8XXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

6238:CBG 02223
gene id: 6238:CBG_02223
uniprot id: A8WS87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

6238:CBG 09495
gene id: 6238:CBG_09495
uniprot id: Q61K76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

6238:CBG 07433
gene id: 6238:CBG_07433
uniprot id: Q8MUK2
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 15417
gene id: 6238:CBG_15417
uniprot id: A8XMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

6238:CBG 05526
gene id: 6238:CBG_05526
uniprot id: A8X031
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10702
gene id: 6238:CBG_10702
uniprot id: A8XBL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 13549
gene id: 6238:CBG_13549
uniprot id: A8XI59
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01365
gene id: 6238:CBG_01365
uniprot id: A8WQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

6238:CBG 19263
gene id: 6238:CBG_19263
uniprot id: Q60W52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family. G(q) subfamily.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Promotes transcription of 3',5'-cyclic phosphodiesterases pde-1 and pde-5, leading to reduced cGMP levels in sensory neurons. This causes suppression of insulin production and signaling which leads to increased daf-16 activity and contributes to increased adult lifespan and resistance to oxidative stress. In addition, by reducing cGMP levels, inhibits TGF-beta signaling pathways. Involved in behavioral response to P.aeruginosa by controlling the expression of daf-7, a member of the TGF-beta family, in ASJ sensory neurons.

6238:CBG 06537
gene id: 6238:CBG_06537
uniprot id: A8X2G9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 03338
gene id: 6238:CBG_03338
uniprot id: Q61YZ4
names: Similarity
messages: Belongs to the LovG family.

6238:CBG 04620
gene id: 6238:CBG_04620
uniprot id: A8WY29
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 05988
gene id: 6238:CBG_05988
uniprot id: A8X163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Membrane

6238:CBG 05032
gene id: 6238:CBG_05032
uniprot id: A8WZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Porcupine subfamily.
messages: Key regulator of the Wnt signaling pathway that mediates lipid modification of Wnt proteins. Acts as a protein-serine O-palmitoleoyltransferase that catalyzes the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. Has a role in cell specification, specifically in blastomere signaling. Involved in cytosketetal polarity. Required for the orientation of mitotic spindle axis.
messages: Membrane

6238:CBG 20134
gene id: 6238:CBG_20134
uniprot id: A8XX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

6238:CBG 13358
gene id: 6238:CBG_13358
uniprot id: A8XHY6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01253
gene id: 6238:CBG_01253
uniprot id: A8WPY7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

6238:CBG 09817
gene id: 6238:CBG_09817
uniprot id: A8X9Q2
names: Similarity
messages: Belongs to the PPC synthetase family.

6238:CBG 08027
gene id: 6238:CBG_08027
uniprot id: A8X5M0
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 05467
gene id: 6238:CBG_05467
uniprot id: A8WZY2
names: Similarity
messages: Belongs to the MIF family.

6238:CBG 12566
gene id: 6238:CBG_12566
uniprot id: A8XG22
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

6238:CBG 18256
gene id: 6238:CBG_18256
uniprot id: A8XS95
names: Similarity
messages: Belongs to the actin family.

6238:CBG 20897
gene id: 6238:CBG_20897
uniprot id: A8XYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 03777
gene id: 6238:CBG_03777
uniprot id: A8WWP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 16622
gene id: 6238:CBG_16622
uniprot id: A8XP60
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

6238:CBG 20958
gene id: 6238:CBG_20958
uniprot id: A8XZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 19689
gene id: 6238:CBG_19689
uniprot id: A8XW74
names: Similarity
messages: Belongs to the MAK16 family.

6238:CBG 00500
gene id: 6238:CBG_00500
uniprot id: A8WMT5
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 04262
gene id: 6238:CBG_04262
uniprot id: A8WX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

6238:CBG 08333
gene id: 6238:CBG_08333
uniprot id: A8X6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

6238:CBG 17688
gene id: 6238:CBG_17688
uniprot id: A8XRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

6238:CBG 07960
gene id: 6238:CBG_07960
uniprot id: A8X5G7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 10976
gene id: 6238:CBG_10976
uniprot id: A8XBZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 04606
gene id: 6238:CBG_04606
uniprot id: A8WY16
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 08609
gene id: 6238:CBG_08609
uniprot id: A8X702
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 21312
gene id: 6238:CBG_21312
uniprot id: A8XZT4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17190
gene id: 6238:CBG_17190
uniprot id: A8XQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 21017
gene id: 6238:CBG_21017
uniprot id: A8XZ64
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

6238:CBG 16654
gene id: 6238:CBG_16654
uniprot id: A8XP86
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 01505
gene id: 6238:CBG_01505
uniprot id: G2J6C6
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 20989
gene id: 6238:CBG_20989
uniprot id: A8XZ42
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 11406
gene id: 6238:CBG_11406
uniprot id: A8XD37
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01804
gene id: 6238:CBG_01804
uniprot id: A8WQS5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

6238:CBG 12060
gene id: 6238:CBG_12060
uniprot id: A8XEG5
names: Similarity
messages: Belongs to the paraoxonase family.

6238:CBG 04746
gene id: 6238:CBG_04746
uniprot id: A8WYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

6238:CBG 09808
gene id: 6238:CBG_09808
uniprot id: A8X9P4
names: Similarity
messages: Belongs to the BLOC1S1 family.

6238:CBG 19226
gene id: 6238:CBG_19226
uniprot id: A8XV46
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 06013
gene id: 6238:CBG_06013
uniprot id: A8X139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

6238:CBG 19682
gene id: 6238:CBG_19682
uniprot id: A8XW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

6238:CBG 02218
gene id: 6238:CBG_02218
uniprot id: A8WS92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SKA1 family.
messages: Component of the ska-1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The ska-1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules. In the complex, it mediates the interaction with microtubules.
messages: Component of the ska1 complex, composed of two copies of ska-1 and a single copy of ska-3. The core complex associates with microtubules and may form dimeric assemblies. Interacts with ska-3 and microtubules.
messages: kinetochore
messages: spindle

6238:CBG 13381
gene id: 6238:CBG_13381
uniprot id: A8XHW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 05356
gene id: 6238:CBG_05356
uniprot id: A8WZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 05655
gene id: 6238:CBG_05655
uniprot id: A8X0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 12733
gene id: 6238:CBG_12733
uniprot id: A8XGG3
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

6238:CBG 00050
gene id: 6238:CBG_00050
uniprot id: A8WM75
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

6238:CBG 11250
gene id: 6238:CBG_11250
uniprot id: A8XDF5
names: Similarity
messages: Belongs to the OXR1 family.

6238:CBG 23248
gene id: 6238:CBG_23248
uniprot id: A8Y4D2
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

6238:CBG 21735
gene id: 6238:CBG_21735
uniprot id: A8Y0L8
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 02389
gene id: 6238:CBG_02389
uniprot id: A8WUF6
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 03795
gene id: 6238:CBG_03795
uniprot id: A8WWR3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Proposed to have a role in neuroprotection.

6238:CBG 04461
gene id: 6238:CBG_04461
uniprot id: A8WXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

6238:CBG 15047
gene id: 6238:CBG_15047
uniprot id: A8XLA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 02473
gene id: 6238:CBG_02473
uniprot id: A8WU86
names: Similarity
messages: Belongs to the FAX family.

6238:CBG 02380
gene id: 6238:CBG_02380
uniprot id: A8WUG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

6238:CBG 15145
gene id: 6238:CBG_15145
uniprot id: A8XLU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DSS1/SEM1 family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the 26S proteasome.
messages: Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Has an essential role in oogenesis and larval growth. Required for intestinal function and default lifespan (By similarity).

6238:CBG 03028
gene id: 6238:CBG_03028
uniprot id: A8WSY7
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 10846
gene id: 6238:CBG_10846
uniprot id: A8XC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 01362
gene id: 6238:CBG_01362
uniprot id: A8WQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

6238:CBG 23137
gene id: 6238:CBG_23137
uniprot id: A8Y4M2
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 07576
gene id: 6238:CBG_07576
uniprot id: A8X4I8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 14696
gene id: 6238:CBG_14696
uniprot id: G2J6U9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 10440
gene id: 6238:CBG_10440
uniprot id: A8XB80
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 16307
gene id: 6238:CBG_16307
uniprot id: A8XNQ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 10736
gene id: 6238:CBG_10736
uniprot id: A8XBP0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01243
gene id: 6238:CBG_01243
uniprot id: A8WPX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 11736
gene id: 6238:CBG_11736
uniprot id: A8XDU8
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03314
gene id: 6238:CBG_03314
uniprot id: A8WUR5
names: Similarity
messages: Belongs to the uridine kinase family.

6238:CBG 19770
gene id: 6238:CBG_19770
uniprot id: A8XWC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

6238:CBG 03823
gene id: 6238:CBG_03823
uniprot id: A8WWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

6238:CBG 01548
gene id: 6238:CBG_01548
uniprot id: A8WRE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

6238:CBG 22845
gene id: 6238:CBG_22845
uniprot id: A8Y369
names: Similarity
messages: Belongs to the FAX family.

6238:CBG 19334
gene id: 6238:CBG_19334
uniprot id: A8XVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

6238:CBG 10070
gene id: 6238:CBG_10070
uniprot id: Q61IU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase D subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, and The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.

6238:CBG 01042
gene id: 6238:CBG_01042
uniprot id: Q626C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNO1 family.
messages: nucleolus

6238:CBG 09152
gene id: 6238:CBG_09152
uniprot id: A8X871
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pescadillo family.
messages: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
messages: nucleolus
messages: nucleoplasm

6238:CBG 08996
gene id: 6238:CBG_08996
uniprot id: A8X820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus

6238:CBG 21319
gene id: 6238:CBG_21319
uniprot id: A8XZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

6238:CBG 09344
gene id: 6238:CBG_09344
uniprot id: A8X9B5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

6238:CBG 04787
gene id: 6238:CBG_04787
uniprot id: A8WYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

6238:CBG 00892
gene id: 6238:CBG_00892
uniprot id: A8WPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein srb family.
messages: Membrane

6238:CBG 13275
gene id: 6238:CBG_13275
uniprot id: Q61BP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of tim-9/tin-9.1 and 3 copies of tim-10/tin-10, named soluble 70 kDa complex. The complex associates with the tim-22 component of the TIM22 complex. Interacts with multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of tim-10/tin-10 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

6238:CBG 05881
gene id: 6238:CBG_05881
uniprot id: A8X1F4
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

6238:CBG 24575
gene id: 6238:CBG_24575
uniprot id: A8WL05
names: Similarity
messages: Belongs to the ZC3H14 family.

6238:CBG 01387
gene id: 6238:CBG_01387
uniprot id: A8WQA6
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 09654
gene id: 6238:CBG_09654
uniprot id: Q61JS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex at least composed of tim-23, tim-17 and tim-50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Mitochondrion inner membrane

6238:CBG 11280
gene id: 6238:CBG_11280
uniprot id: A8XDE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 03475
gene id: 6238:CBG_03475
uniprot id: A8WV57
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 21755
gene id: 6238:CBG_21755
uniprot id: Q60QM6
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 20119
gene id: 6238:CBG_20119
uniprot id: A8XX47
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

6238:CBG 05272
gene id: 6238:CBG_05272
uniprot id: A8WZI3
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 06904
gene id: 6238:CBG_06904
uniprot id: A8X3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 19625
gene id: 6238:CBG_19625
uniprot id: A8XW18
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18033
gene id: 6238:CBG_18033
uniprot id: A8XSV7
names: Similarity
messages: Belongs to the E(R) family.

6238:CBG 04197
gene id: 6238:CBG_04197
uniprot id: A8WWE4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 08168
gene id: 6238:CBG_08168
uniprot id: A8X5Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15765
gene id: 6238:CBG_15765
uniprot id: A8XMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

6238:CBG 01803
gene id: 6238:CBG_01803
uniprot id: A8WQS6
names: Similarity
messages: Belongs to the HPF1 family.

6238:CBG 02196
gene id: 6238:CBG_02196
uniprot id: A8WSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

6238:CBG 06270
gene id: 6238:CBG_06270
uniprot id: A8X0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 02202
gene id: 6238:CBG_02202
uniprot id: A8WSA7
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 12984
gene id: 6238:CBG_12984
uniprot id: A8XGU0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

6238:CBG 23406
gene id: 6238:CBG_23406
uniprot id: A8Y3Z6
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

6238:CBG 11957
gene id: 6238:CBG_11957
uniprot id: A8XEN9
names: Similarity
messages: Belongs to the argonaute family.

6238:CBG 13531
gene id: 6238:CBG_13531
uniprot id: A8XI41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

6238:CBG 00033
gene id: 6238:CBG_00033
uniprot id: A8WM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

6238:CBG 21104
gene id: 6238:CBG_21104
uniprot id: A8XZG9
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

6238:CBG 05410
gene id: 6238:CBG_05410
uniprot id: Q61UA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C78 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Interacts with odr-4.
messages: Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins. Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels.
messages: perinuclear region

6238:CBG 03822
gene id: 6238:CBG_03822
uniprot id: A8WWU1
names: Similarity
messages: Belongs to the LTV1 family.

6238:CBG 06104
gene id: 6238:CBG_06104
uniprot id: A8X0W3
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

6238:CBG 13128
gene id: 6238:CBG_13128
uniprot id: A8XH46
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 00320
gene id: 6238:CBG_00320
uniprot id: A8WMP8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 16808
gene id: 6238:CBG_16808
uniprot id: A8XPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF1 family.
messages: CPSF is a heterotetramer composed of four distinct subunits 160 (cpsf-1), 100 (cpsf-2), 70 (cpsf-3), and 30 kDa (cpsf-4).
messages: CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
messages: Nucleus

6238:CBG 02517
gene id: 6238:CBG_02517
uniprot id: A8WU48
names: Similarity
messages: Belongs to the CTNNBIP1 family.

6238:CBG 06889
gene id: 6238:CBG_06889
uniprot id: Q61QT3
names: Function
messages: May have a role in mesendoderm development during embryogenesis.

6238:CBG 13085
gene id: 6238:CBG_13085
uniprot id: A8XH19
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

6238:CBG 12225
gene id: 6238:CBG_12225
uniprot id: A8XEY3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

6238:CBG 12465
gene id: 6238:CBG_12465
uniprot id: A8XFI0
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 15626
gene id: 6238:CBG_15626
uniprot id: A8XME8
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 08956
gene id: 6238:CBG_08956
uniprot id: A8X7R3
uniprot id: A8X7R4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 17045
gene id: 6238:CBG_17045
uniprot id: A8XQD0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

6238:CBG 06011
gene id: 6238:CBG_06011
uniprot id: A8X141
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

6238:CBG 20641
gene id: 6238:CBG_20641
uniprot id: Q60T34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sra family.
messages: Membrane

6238:CBG 15767
gene id: 6238:CBG_15767
uniprot id: Q615A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit sec-11 and three accessory subunits spcs-1, spcs-2 and spcs-3. The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
messages: Endoplasmic reticulum membrane

6238:CBG 10003
gene id: 6238:CBG_10003
uniprot id: A8XA54
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

6238:CBG 17298
gene id: 6238:CBG_17298
uniprot id: A8XQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 04578
gene id: 6238:CBG_04578
uniprot id: A8WXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

6238:CBG 08781
gene id: 6238:CBG_08781
uniprot id: A8X7D7
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 02509
gene id: 6238:CBG_02509
uniprot id: A8WU55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

6238:CBG 00744
gene id: 6238:CBG_00744
uniprot id: A8WN59
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

6238:CBG 03472
gene id: 6238:CBG_03472
uniprot id: A8WV54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

6238:CBG 24609
gene id: 6238:CBG_24609
uniprot id: A8WL34
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

6238:CBG 24151
gene id: 6238:CBG_24151
uniprot id: A8WK32
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 07708
gene id: 6238:CBG_07708
uniprot id: A8X488
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

6238:CBG 12498
gene id: 6238:CBG_12498
uniprot id: Q9U4H8
names: Similarity
messages: Belongs to the calponin family.

6238:CBG 18073
gene id: 6238:CBG_18073
uniprot id: A8XSZ1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

6238:CBG 02775
gene id: 6238:CBG_02775
uniprot id: G2J6F0
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 18095
gene id: 6238:CBG_18095
uniprot id: Q60YT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family. MAPR subfamily.
messages: Heme-binding protein.
messages: Secreted
messages: The cytochrome b5 heme-binding domain was proven to bind heme, although it lacks the conserved iron-binding His residues at position 136 and 169.

6238:CBG 09987
gene id: 6238:CBG_09987
uniprot id: A8XA40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death (By similarity).
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Glycosylation is important for its biological activity.
messages: perinuclear region

6238:CBG 22047
gene id: 6238:CBG_22047
uniprot id: A8Y1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RBP10 is part of the core element with the central large cleft (By similarity).
messages: Nucleus

6238:CBG 15244
gene id: 6238:CBG_15244
uniprot id: A8XLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: FMRFamides and FMRFamide-like peptides are neuropeptides.
messages: Secreted

6238:CBG 10085
gene id: 6238:CBG_10085
uniprot id: A8XAC7
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

6238:CBG 04603
gene id: 6238:CBG_04603
uniprot id: A8WY13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 16079
gene id: 6238:CBG_16079
uniprot id: A8XN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 20294
gene id: 6238:CBG_20294
uniprot id: A8XXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 01744
gene id: 6238:CBG_01744
uniprot id: A8WQY3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
messages: Mitochondrion intermembrane space

6238:CBG 01504
gene id: 6238:CBG_01504
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 07031
gene id: 6238:CBG_07031
uniprot id: A8X3V3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 02943
gene id: 6238:CBG_02943
uniprot id: A8WT57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

6238:CBG 20346
gene id: 6238:CBG_20346
uniprot id: A8XXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

6238:CBG 23539
gene id: 6238:CBG_23539
uniprot id: A8Y3P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane

6238:CBG 09795
gene id: 6238:CBG_09795
uniprot id: A8X9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

6238:CBG 09260
gene id: 6238:CBG_09260
uniprot id: A8X9I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 23906
gene id: 6238:CBG_23906
uniprot id: A8WJJ8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01802
gene id: 6238:CBG_01802
uniprot id: A8WQS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 12734
gene id: 6238:CBG_12734
uniprot id: A8XGG4
names: Similarity
messages: Belongs to the TAPR1 family.

6238:CBG 04164
gene id: 6238:CBG_04164
uniprot id: A8WWB3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03145
gene id: 6238:CBG_03145
uniprot id: A8WSP3
names: Similarity
messages: Belongs to the actin family.

6238:CBG 20985
gene id: 6238:CBG_20985
uniprot id: A8XZ38
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 02256
gene id: 6238:CBG_02256
uniprot id: A8WS58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

6238:CBG 08408
gene id: 6238:CBG_08408
uniprot id: A8X6H5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13528
gene id: 6238:CBG_13528
uniprot id: A8XI38
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 04173
gene id: 6238:CBG_04173
uniprot id: A8WWC2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

6238:CBG 01949
gene id: 6238:CBG_01949
uniprot id: A8WRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

6238:CBG 03956
gene id: 6238:CBG_03956
uniprot id: A8WVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

6238:CBG 07217
gene id: 6238:CBG_07217
uniprot id: A8X3G6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13492
gene id: 6238:CBG_13492
uniprot id: A8XI07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

6238:CBG 19173
gene id: 6238:CBG_19173
uniprot id: A8XV01
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 14941
gene id: 6238:CBG_14941
uniprot id: A8XL21
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23911
gene id: 6238:CBG_23911
uniprot id: A8WJK2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

6238:CBG 11589
gene id: 6238:CBG_11589
uniprot id: A8XDK5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

6238:CBG 02744
gene id: 6238:CBG_02744
uniprot id: A8WTL5
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

6238:CBG 12002
gene id: 6238:CBG_12002
uniprot id: A8XEB5
names: Similarity
messages: Belongs to the TPPP family.

6238:CBG 11542
gene id: 6238:CBG_11542
uniprot id: A8XDG1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

6238:CBG 02878
gene id: 6238:CBG_02878
uniprot id: A8WTB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 02597
gene id: 6238:CBG_02597
uniprot id: A8WTY7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 16614
gene id: 6238:CBG_16614
uniprot id: Q612Q9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Cytoplasm
messages: Rough endoplasmic reticulum
messages: cytosol

6238:CBG 00732
gene id: 6238:CBG_00732
uniprot id: A8WN70
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

6238:CBG 07603
gene id: 6238:CBG_07603
uniprot id: A8X4G6
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17593
gene id: 6238:CBG_17593
uniprot id: A8XRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 18913
gene id: 6238:CBG_18913
uniprot id: A8XUC4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 19790
gene id: 6238:CBG_19790
uniprot id: A8XWB0
names: Subcellular Location Annotation
messages: Cytoplasm

6238:CBG 05762
gene id: 6238:CBG_05762
uniprot id: A8X1P4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

6238:CBG 13346
gene id: 6238:CBG_13346
uniprot id: A8XHZ7
names: Similarity
messages: Belongs to the peptidase C12 family.

6238:CBG 06974
gene id: 6238:CBG_06974
uniprot id: A8X406
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

6238:CBG 09957
gene id: 6238:CBG_09957
uniprot id: A8XA16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 17976
gene id: 6238:CBG_17976
uniprot id: A8XSQ4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01506
gene id: 6238:CBG_01506
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 16816
gene id: 6238:CBG_16816
uniprot id: A8XPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

6238:CBG 13432
gene id: 6238:CBG_13432
uniprot id: A8XHS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

6238:CBG 14163
gene id: 6238:CBG_14163
uniprot id: A8XJF4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 01654
gene id: 6238:CBG_01654
uniprot id: A8WR57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 00668
gene id: 6238:CBG_00668
uniprot id: A8WNB9
names: Similarity
messages: Belongs to the group II decarboxylase family.

6238:CBG 16756
gene id: 6238:CBG_16756
uniprot id: A8XPR4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18394
gene id: 6238:CBG_18394
uniprot id: A8XSL8
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

6238:CBG 03753
gene id: 6238:CBG_03753
uniprot id: A8WWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 01391
gene id: 6238:CBG_01391
uniprot id: A8WQB0
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 21168
gene id: 6238:CBG_21168
uniprot id: A8XZC3
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

6238:CBG 00291
gene id: 6238:CBG_00291
uniprot id: A8WMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

6238:CBG 11300
gene id: 6238:CBG_11300
uniprot id: A8XDC3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01052
gene id: 6238:CBG_01052
uniprot id: A8WP05
names: Similarity
messages: Belongs to the Mo25 family.

6238:CBG 03443
gene id: 6238:CBG_03443
uniprot id: Q61YQ1
names: Cofactor
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Homotetramer.

6238:CBG 18688
gene id: 6238:CBG_18688
uniprot id: A8XTW8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

6238:CBG 14886
gene id: 6238:CBG_14886
uniprot id: A8XKX0
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

6238:CBG 12661
gene id: 6238:CBG_12661
uniprot id: A8XGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

6238:CBG 04060
gene id: 6238:CBG_04060
uniprot id: A8WW43
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02283
gene id: 6238:CBG_02283
uniprot id: G2J6N5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 05373
gene id: 6238:CBG_05373
uniprot id: A8WZQ3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 11851
gene id: 6238:CBG_11851
uniprot id: A8XE57
names: Function
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

6238:CBG 18599
gene id: 6238:CBG_18599
uniprot id: A8XTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

6238:CBG 20196
gene id: 6238:CBG_20196
uniprot id: A8XX81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

6238:CBG 17200
gene id: 6238:CBG_17200
uniprot id: A8XQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

6238:CBG 03221
gene id: 6238:CBG_03221
uniprot id: A8WSI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

6238:CBG 05858
gene id: 6238:CBG_05858
uniprot id: A8X1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

6238:CBG 15963
gene id: 6238:CBG_15963
uniprot id: A8XND9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 23733
gene id: 6238:CBG_23733
uniprot id: A8WJ61
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

6238:CBG 08019
gene id: 6238:CBG_08019
uniprot id: A8X5L4
names: Similarity
messages: Belongs to the NDRG family.

6238:CBG 09750
gene id: 6238:CBG_09750
uniprot id: A8XAJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 13234
gene id: 6238:CBG_13234
uniprot id: A8XHD1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

6238:CBG 13820
gene id: 6238:CBG_13820
uniprot id: A8XIS2
names: Similarity
messages: Belongs to the glutamine synthetase family.

6238:CBG 05736
gene id: 6238:CBG_05736
uniprot id: A8X1R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

6238:CBG 16480
gene id: 6238:CBG_16480
uniprot id: A8XP56
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 09838
gene id: 6238:CBG_09838
uniprot id: A8X9S0
names: Similarity
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.

6238:CBG 17632
gene id: 6238:CBG_17632
uniprot id: A8XRN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

6238:CBG 03775
gene id: 6238:CBG_03775
uniprot id: G2J6F9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 16005
gene id: 6238:CBG_16005
uniprot id: A8XNA7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

6238:CBG 23066
gene id: 6238:CBG_23066
uniprot id: A8Y4S6
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

6238:CBG 17919
gene id: 6238:CBG_17919
uniprot id: A8XS40
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 20791
gene id: 6238:CBG_20791
uniprot id: G2J716
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

6238:CBG 05087
gene id: 6238:CBG_05087
uniprot id: A8WZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 22795
gene id: 6238:CBG_22795
uniprot id: A8Y2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

6238:CBG 06105
gene id: 6238:CBG_06105
uniprot id: A8X0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 20860
gene id: 6238:CBG_20860
uniprot id: A8XYT3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 13533
gene id: 6238:CBG_13533
uniprot id: A8XI43
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

6238:CBG 14493
gene id: 6238:CBG_14493
uniprot id: A8XK18
names: Similarity
messages: Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.

6238:CBG 01590
gene id: 6238:CBG_01590
uniprot id: A8WRA8
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

6238:CBG 11176
gene id: 6238:CBG_11176
uniprot id: A8XCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

6238:CBG 06579
gene id: 6238:CBG_06579
uniprot id: A8X2K8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 08078
gene id: 6238:CBG_08078
uniprot id: A8X5R3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

6238:CBG 13580
gene id: 6238:CBG_13580
uniprot id: A8XI84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

6238:CBG 05844
gene id: 6238:CBG_05844
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 17162
gene id: 6238:CBG_17162
uniprot id: Q611C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity).

6238:CBG 13174
gene id: 6238:CBG_13174
uniprot id: A8XH82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

6238:CBG 09606
gene id: 6238:CBG_09606
uniprot id: A8X8P2
names: Similarity
messages: Belongs to the peptidase S10 family.

6238:CBG 13059
gene id: 6238:CBG_13059
uniprot id: A8XGZ6
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 09378
gene id: 6238:CBG_09378
uniprot id: A8X984
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

6238:CBG 20951
gene id: 6238:CBG_20951
uniprot id: A8XZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 06866
gene id: 6238:CBG_06866
uniprot id: A8X389
names: Similarity
messages: Belongs to the cytochrome b5 family.

6238:CBG 09874
gene id: 6238:CBG_09874
uniprot id: A8X9V4
names: Function
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.
messages: Monoglutamylase which modifies tubulin, adding a single glutamate on the gamma-carboxyl group of specific glutamate residues of target proteins. Involved in the side-chain initiation step of the polyglutamylation reaction but not in the elongation step. Preferentially modifies beta-tail tubulin over the alpha-tubulin. Involved in side-chain glutamylation of tubulin in sensory cilia. Together with ttll-5 and ttll-11, required for male mating.

6238:CBG 08070
gene id: 6238:CBG_08070
uniprot id: A8X5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

6238:CBG 04194
gene id: 6238:CBG_04194
uniprot id: A8WWE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 12037
gene id: 6238:CBG_12037
uniprot id: A8XEE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

6238:CBG 01255
gene id: 6238:CBG_01255
uniprot id: A8WPY9
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 12655
gene id: 6238:CBG_12655
uniprot id: Q61D31
names: Domain
names: Function
names: Subunit
messages: Homodimer or homotetramer.
messages: May inhibit the chaperone activity of HSP70/HSC70 by promoting substrate release in an ATP-dependent manner.
messages: The BAG domain probably mediates direct interaction with HSP70.

6238:CBG 23625
gene id: 6238:CBG_23625
uniprot id: A8WIY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

6238:CBG 03362
gene id: 6238:CBG_03362
uniprot id: A8WUV5
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 12063
gene id: 6238:CBG_12063
uniprot id: A8XEG8
names: Function
names: Similarity
messages: Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.
messages: Belongs to the Diphthine--ammonia ligase family.

6238:CBG 05589
gene id: 6238:CBG_05589
uniprot id: A8X080
names: Similarity
messages: Belongs to the ERG4/ERG24 family.

6238:CBG 05561
gene id: 6238:CBG_05561
uniprot id: A8X056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 01390
gene id: 6238:CBG_01390
uniprot id: A8WQA9
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 13321
gene id: 6238:CBG_13321
uniprot id: G2J6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

6238:CBG 10822
gene id: 6238:CBG_10822
uniprot id: A8XBV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 20111
gene id: 6238:CBG_20111
uniprot id: A8XX43
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

6238:CBG 01480
gene id: 6238:CBG_01480
uniprot id: A8WQK9
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 20644
gene id: 6238:CBG_20644
uniprot id: Q60T32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sra family.
messages: Membrane

6238:CBG 22293
gene id: 6238:CBG_22293
uniprot id: A8Y201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

6238:CBG 22764
gene id: 6238:CBG_22764
uniprot id: A8Y2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

6238:CBG 06978
gene id: 6238:CBG_06978
uniprot id: A8X402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: extracellular matrix

6238:CBG 00462
gene id: 6238:CBG_00462
uniprot id: Q628A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT4 family.
messages: Interacts with spt-5 to form DSIF. DSIF interacts with RNA polymerase II and with the positive transcription elongation factor b complex (P-TEFb complex), which is composed of cdk-9 and cyclin-T (By similarity).
messages: May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity).
messages: Nucleus

6238:CBG 11475
gene id: 6238:CBG_11475
uniprot id: Q61FW2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Probable component of the SCF(sel-10) E3 ubiquitin-protein ligase complex which includes skr-1 and F-box domain-containing protein sel-10 as a substrate recognition component. Interacts with fem-1, fem-2, and fem-3. Interacts with the intracellular domain of glp-1 and sel-12. Interacts with lin-12. Interacts with skr-1. Interacts with zyg-1.
messages: Probable substrate recognition component of SCF (SKP1-CUL-F-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates synapse elimination in early development in the motor neuron HSNL. Cell autonomous negative regulator of lin-12/Notch-mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis. May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation. Involved in sex determination by promoting female development. Potential regulator of presenilin. May have a role in egg laying. Regulates zyg-1 levels (possibly redundantly with lin-23) to control centrosome duplication during mitosis. Negatively regulates lin-45 activity and protein stability, probably by targeting it for ubiquitination and proteasomal degradation.
messages: axon

6238:CBG 17856
gene id: 6238:CBG_17856
uniprot id: A8XRX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 11395
gene id: 6238:CBG_11395
uniprot id: A8XD44
names: Similarity
messages: Belongs to the GAMAD family.

6238:CBG 03015
gene id: 6238:CBG_03015
uniprot id: A8WSZ7
names: Similarity
messages: Belongs to the VPS11 family.

6238:CBG 02116
gene id: 6238:CBG_02116
uniprot id: A8WS09
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

6238:CBG 23242
gene id: 6238:CBG_23242
uniprot id: A8Y4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

6238:CBG 03134
gene id: 6238:CBG_03134
uniprot id: A8WSQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

6238:CBG 18122
gene id: 6238:CBG_18122
uniprot id: A8XT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

6238:CBG 07110
gene id: 6238:CBG_07110
uniprot id: A8X3N9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

6238:CBG 03214
gene id: 6238:CBG_03214
uniprot id: A8WSJ4
names: Similarity
messages: Belongs to the enolase family.

6238:CBG 10495
gene id: 6238:CBG_10495
uniprot id: A8XAX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 11646
gene id: 6238:CBG_11646
uniprot id: A8XDQ0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 09425
gene id: 6238:CBG_09425
uniprot id: A8X949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

6238:CBG 03371
gene id: 6238:CBG_03371
uniprot id: A8WUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Membrane

6238:CBG 02576
gene id: 6238:CBG_02576
uniprot id: A8WU03
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 12412
gene id: 6238:CBG_12412
uniprot id: A8XFD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

6238:CBG 05886
gene id: 6238:CBG_05886
uniprot id: G2J6F9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 13352
gene id: 6238:CBG_13352
uniprot id: A8XHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

6238:CBG 04512
gene id: 6238:CBG_04512
uniprot id: A8WXQ2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22797
gene id: 6238:CBG_22797
uniprot id: A8Y2W6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

6238:CBG 21258
gene id: 6238:CBG_21258
uniprot id: A8XZP8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

6238:CBG 21322
gene id: 6238:CBG_21322
uniprot id: A8XZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 13704
gene id: 6238:CBG_13704
uniprot id: A8XII4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 06058
gene id: 6238:CBG_06058
uniprot id: G2J6F9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 02772
gene id: 6238:CBG_02772
uniprot id: A8WTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Membrane

6238:CBG 02381
gene id: 6238:CBG_02381
uniprot id: A8WUG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Interaction with par-3 required for the peripheral localization of par-6 and to form a par-3/par-6/pkc-3 complex, which is activated when cdc-42 interacts with par-6. Binds avidly to the phosphotyrosine interaction domain (PID) of a novel pkc-3 adapter protein num-1, which enables tethering and targeting of pkc-3 to the cell periphery (By similarity).
messages: Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. Required for the expression of antimicrobial peptide nlp-29 in response in response to fungal infection or physical injury.
messages: cytoskeleton

6238:CBG 19960
gene id: 6238:CBG_19960
uniprot id: A8XWT7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 07380
gene id: 6238:CBG_07380
uniprot id: A8X4W5
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18395
gene id: 6238:CBG_18395
uniprot id: A8XSL9
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 01722
gene id: 6238:CBG_01722
uniprot id: Q623U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the JMJD6 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase.
messages: Interacts with ced-5 and ced-12.
messages: Nucleus

6238:CBG 18211
gene id: 6238:CBG_18211
uniprot id: Q60YJ7
names: Similarity
messages: Belongs to the CSN12 family.

6238:CBG 13338
gene id: 6238:CBG_13338
uniprot id: A8XHL9
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

6238:CBG 03573
gene id: 6238:CBG_03573
uniprot id: A8WVD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway.
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the nuclear pore complex (NPC). Probably part of the GATOR complex.
messages: Lysosome membrane
messages: Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus.
messages: nuclear pore complex

6238:CBG 12805
gene id: 6238:CBG_12805
uniprot id: A8XFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

6238:CBG 13928
gene id: 6238:CBG_13928
uniprot id: A8XJ07
names: Similarity
messages: Belongs to the NAD kinase family.

6238:CBG 12118
gene id: 6238:CBG_12118
uniprot id: A8XES8
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 09586
gene id: 6238:CBG_09586
uniprot id: Q61JZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP2 subfamily.
messages: Component of the Arp2/3 complex.
messages: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity).
messages: cytoskeleton

6238:CBG 07625
gene id: 6238:CBG_07625
uniprot id: A8X4F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 04029
gene id: 6238:CBG_04029
uniprot id: A8WW14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

6238:CBG 14244
gene id: 6238:CBG_14244
uniprot id: A8XJL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 12641
gene id: 6238:CBG_12641
uniprot id: Q61D44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).
messages: Nucleus

6238:CBG 07044
gene id: 6238:CBG_07044
uniprot id: A8X3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

6238:CBG 15298
gene id: 6238:CBG_15298
uniprot id: A8XLW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. Cooperates with ykt-6 for proper expression of Golgi-resident proteins. Required along with ykt-6 for normal embryonic development, seam cell division or differentiation, and ray formation (By similarity).

6238:CBG 18063
gene id: 6238:CBG_18063
uniprot id: A8XSY2
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

6238:CBG 08772
gene id: 6238:CBG_08772
uniprot id: A8X7D0
names: Subcellular Location Annotation
messages: nucleolus

6238:CBG 21512
gene id: 6238:CBG_21512
uniprot id: A8Y0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

6238:CBG 15945
gene id: 6238:CBG_15945
uniprot id: A8XNF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

6238:CBG 17559
gene id: 6238:CBG_17559
uniprot id: A8XR87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

6238:CBG 17652
gene id: 6238:CBG_17652
uniprot id: A8XRL7
names: Similarity
messages: Belongs to the threonine aldolase family.

6238:CBG 07494
gene id: 6238:CBG_07494
uniprot id: G2J6L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 18025
gene id: 6238:CBG_18025
uniprot id: A8XSU9
names: Similarity
messages: Belongs to the PP2C family.

6238:CBG 04485
gene id: 6238:CBG_04485
uniprot id: A8WXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA or eicosapentaenoic acid (EPA) as the acyl donor. Prefers sn-2-LPI rather than sn-1-LPI as the acyl acceptor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (By similarity).
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

6238:CBG 03286
gene id: 6238:CBG_03286
uniprot id: A8WSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

6238:CBG 16596
gene id: 6238:CBG_16596
uniprot id: A8XPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

6238:CBG 02876
gene id: 6238:CBG_02876
uniprot id: A8WTB3
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 00890
gene id: 6238:CBG_00890
uniprot id: A8WPE1
names: Similarity
messages: Belongs to the MPI phosphatase family.

6238:CBG 20006
gene id: 6238:CBG_20006
uniprot id: A8XWX1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

6238:CBG 02961
gene id: 6238:CBG_02961
uniprot id: A8WT40
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus

6238:CBG 06227
gene id: 6238:CBG_06227
uniprot id: A8X0L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

6238:CBG 10906
gene id: 6238:CBG_10906
uniprot id: A8XC87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

6238:CBG 02768
gene id: 6238:CBG_02768
uniprot id: Q8MUK1
names: Similarity
messages: Belongs to the cyclin family.

6238:CBG 01600
gene id: 6238:CBG_01600
uniprot id: A8WRA1
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 04228
gene id: 6238:CBG_04228
uniprot id: A8WWG8
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

6238:CBG 16441
gene id: 6238:CBG_16441
uniprot id: A8XP32
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

6238:CBG 21316
gene id: 6238:CBG_21316
uniprot id: A8XZT8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 06153
gene id: 6238:CBG_06153
uniprot id: A8X0S9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 13324
gene id: 6238:CBG_13324
uniprot id: A8XHK9
names: Similarity
messages: Belongs to the polyprenol kinase family.

6238:CBG 21507
gene id: 6238:CBG_21507
uniprot id: A8Y099
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

6238:CBG 09235
gene id: 6238:CBG_09235
uniprot id: A8X9J7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 20959
gene id: 6238:CBG_20959
uniprot id: A8XZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 12296
gene id: 6238:CBG_12296
uniprot id: A8XF73
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13774
gene id: 6238:CBG_13774
uniprot id: A8XIN8
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 03612
gene id: 6238:CBG_03612
uniprot id: Q9NBK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Cytoplasm
messages: The L3 protein is a component of the large subunit of cytoplasmic ribosomes.

6238:CBG 20706
gene id: 6238:CBG_20706
uniprot id: A8XYF4
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 18982
gene id: 6238:CBG_18982
uniprot id: A8XUH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 04592
gene id: 6238:CBG_04592
uniprot id: A8WY05
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 03859
gene id: 6238:CBG_03859
uniprot id: A8WWX7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 23450
gene id: 6238:CBG_23450
uniprot id: A8Y3V9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 00920
gene id: 6238:CBG_00920
uniprot id: A8WPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

6238:CBG 16451
gene id: 6238:CBG_16451
uniprot id: A8XP38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

6238:CBG 23351
gene id: 6238:CBG_23351
uniprot id: A8Y446
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 15273
gene id: 6238:CBG_15273
uniprot id: A8XLI3
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 08743
gene id: 6238:CBG_08743
uniprot id: A8X7A3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

6238:CBG 19169
gene id: 6238:CBG_19169
uniprot id: A8XUZ9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02553
gene id: 6238:CBG_02553
uniprot id: A8WU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 01027
gene id: 6238:CBG_01027
uniprot id: A8WP28
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 19957
gene id: 6238:CBG_19957
uniprot id: A8XWT4
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

6238:CBG 12182
gene id: 6238:CBG_12182
uniprot id: A8XF19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

6238:CBG 12266
gene id: 6238:CBG_12266
uniprot id: A8XF47
names: Similarity
messages: Belongs to the TIP41 family.

6238:CBG 23485
gene id: 6238:CBG_23485
uniprot id: A8Y3T3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15117
gene id: 6238:CBG_15117
uniprot id: A8XLF8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 19772
gene id: 6238:CBG_19772
uniprot id: A8XWC6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

6238:CBG 16565
gene id: 6238:CBG_16565
uniprot id: A8XPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

6238:CBG 20339
gene id: 6238:CBG_20339
uniprot id: G2J711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

6238:CBG 00101
gene id: 6238:CBG_00101
uniprot id: A8WMA6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 06840
gene id: 6238:CBG_06840
uniprot id: A8X369
names: Similarity
messages: Belongs to the CWC26 family.

6238:CBG 09634
gene id: 6238:CBG_09634
uniprot id: A8X8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 18941
gene id: 6238:CBG_18941
uniprot id: A8XUE5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

6238:CBG 13509
gene id: 6238:CBG_13509
uniprot id: A8XI23
names: Similarity
messages: Belongs to the HSBP1 family.

6238:CBG 08593
gene id: 6238:CBG_08593
uniprot id: A8X716
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03851
gene id: 6238:CBG_03851
uniprot id: A8WWX0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 16758
gene id: 6238:CBG_16758
uniprot id: A8XPR6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09483
gene id: 6238:CBG_09483
uniprot id: A8X904
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

6238:CBG 11579
gene id: 6238:CBG_11579
uniprot id: A8XDJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

6238:CBG 22137
gene id: 6238:CBG_22137
uniprot id: Q60PR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the semaphorin family.
messages: Interacts with plx-2.
messages: Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. Involved in axon guidance. Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus axon guidance and/or fasciculation of DD/VD neurons.
messages: Secreted

6238:CBG 03436
gene id: 6238:CBG_03436
uniprot id: A8WV23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

6238:CBG 17857
gene id: 6238:CBG_17857
uniprot id: A8XRX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 09310
gene id: 6238:CBG_09310
uniprot id: A8X9E4
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 12006
gene id: 6238:CBG_12006
uniprot id: A8XEB8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 10094
gene id: 6238:CBG_10094
uniprot id: A8XAD6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

6238:CBG 01180
gene id: 6238:CBG_01180
uniprot id: A8WPS1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 15112
gene id: 6238:CBG_15112
uniprot id: A8XLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

6238:CBG 02091
gene id: 6238:CBG_02091
uniprot id: A8WRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

6238:CBG 05912
gene id: 6238:CBG_05912
uniprot id: A8X1C8
names: Similarity
messages: Belongs to the importin alpha family.

6238:CBG 21051
gene id: 6238:CBG_21051
uniprot id: A8XZA8
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

6238:CBG 10794
gene id: 6238:CBG_10794
uniprot id: A8XBT5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

6238:CBG 01248
gene id: 6238:CBG_01248
uniprot id: A8WPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 11215
gene id: 6238:CBG_11215
uniprot id: Q61GH1
names: Similarity
messages: Belongs to the BCP1 family.

6238:CBG 07091
gene id: 6238:CBG_07091
uniprot id: A8X3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

6238:CBG 18029
gene id: 6238:CBG_18029
uniprot id: A8XSV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat neurobeachin family.
messages: Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells (By similarity).
messages: Cytoplasm
messages: Interacts with RII subunit of PKA.
messages: Membrane
messages: Nucleus

6238:CBG 19969
gene id: 6238:CBG_19969
uniprot id: A8XWU5
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 17617
gene id: 6238:CBG_17617
uniprot id: A8XRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

6238:CBG 08519
gene id: 6238:CBG_08519
uniprot id: A8X6R6
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 00848
gene id: 6238:CBG_00848
uniprot id: A8WPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

6238:CBG 16650
gene id: 6238:CBG_16650
uniprot id: A8XP82
names: Similarity
messages: Belongs to the DNase II family.

6238:CBG 05165
gene id: 6238:CBG_05165
uniprot id: A8WZA1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 15331
gene id: 6238:CBG_15331
uniprot id: A8XLY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

6238:CBG 18572
gene id: 6238:CBG_18572
uniprot id: A8XTL9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 23504
gene id: 6238:CBG_23504
uniprot id: A8Y3R8
names: Similarity
messages: Belongs to the alpha-actinin family.

6238:CBG 24615
gene id: 6238:CBG_24615
uniprot id: A8WL28
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with hcp-3 and hcp-4 to form a complex. Interacts with hcp-4, him-10, kbp-3, kbp-4, kbp-5, knl-3, and ndc-80. Interacts with kbp-1, kbp-2 and mis-12; which make up the MIS12 complex.
messages: Proposed to be part of the KMN network incorporating the MIS12 complex and NDC80 complex that is required for establishing the kinetochore-microtubule interface that aids in chromosome segregation during meiotic and mitotic cell division. Appears to function downstream of hcp-3 (CENP-A) and hcp-4 (CENP-C) in the kinetochore assembly hierarchy. Has a role in the correct localization of spdl-1 and the RZZ complex that is composed of rod-1, czw-1 and zwl-1. Required for the recruitment of spindle-assembly checkpoint components bub-1 and mdf-1/2 to unattached kinetochores (By similarity).
messages: The N-terminus contains a number of repeats which contribute additively to bub-1 recruitment to unattached kinetochores. The repeats are not required for localization to kinetochores (By similarity).
messages: cell cortex
messages: kinetochore

6238:CBG 14519
gene id: 6238:CBG_14519
uniprot id: A8XK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

6238:CBG 01383
gene id: 6238:CBG_01383
uniprot id: A8WQA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 07849
gene id: 6238:CBG_07849
uniprot id: A8X596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 08370
gene id: 6238:CBG_08370
uniprot id: A8X6E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Secreted

6238:CBG 21054
gene id: 6238:CBG_21054
uniprot id: A8XZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

6238:CBG 03840
gene id: 6238:CBG_03840
uniprot id: A8WWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

6238:CBG 13109
gene id: 6238:CBG_13109
uniprot id: A8XH38
names: Similarity
messages: Belongs to the peptidase S10 family.

6238:CBG 16516
gene id: 6238:CBG_16516
uniprot id: A8XPD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 02224
gene id: 6238:CBG_02224
uniprot id: A8WS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

6238:CBG 19390
gene id: 6238:CBG_19390
uniprot id: A8XVI5
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03381
gene id: 6238:CBG_03381
uniprot id: A8WUX1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 04227
gene id: 6238:CBG_04227
uniprot id: A8WWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

6238:CBG 09696
gene id: 6238:CBG_09696
uniprot id: A8X8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 01779
gene id: 6238:CBG_01779
uniprot id: A8WQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Membrane

6238:CBG 24678
gene id: 6238:CBG_24678
uniprot id: A8WL85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Chromosome
messages: Nucleus

6238:CBG 19955
gene id: 6238:CBG_19955
uniprot id: A8XWT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 22157
gene id: 6238:CBG_22157
uniprot id: Q60PP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Positively regulates a late step in synaptic vesicle exocytosis.
messages: cytosol

6238:CBG 13193
gene id: 6238:CBG_13193
uniprot id: A8XH96
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 04431
gene id: 6238:CBG_04431
uniprot id: A8WXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

6238:CBG 23369
gene id: 6238:CBG_23369
uniprot id: A8Y431
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 01395
gene id: 6238:CBG_01395
uniprot id: A8WQB4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 19029
gene id: 6238:CBG_19029
uniprot id: A8XUL7
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 05278
gene id: 6238:CBG_05278
uniprot id: A8WZI8
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 03659
gene id: 6238:CBG_03659
uniprot id: A8WVJ1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02845
gene id: 6238:CBG_02845
uniprot id: A8WTE1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

6238:CBG 09009
gene id: 6238:CBG_09009
uniprot id: A8X809
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 12876
gene id: 6238:CBG_12876
uniprot id: A8XFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 20879
gene id: 6238:CBG_20879
uniprot id: A8XYV2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

6238:CBG 10810
gene id: 6238:CBG_10810
uniprot id: A8XBU7
names: Subcellular Location Annotation
messages: cilium

6238:CBG 09488
gene id: 6238:CBG_09488
uniprot id: A8X902
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 12567
gene id: 6238:CBG_12567
uniprot id: A8XG23
names: Similarity
messages: Belongs to the cuticular collagen family.

6238:CBG 05812
gene id: 6238:CBG_05812
uniprot id: A8X1K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

6238:CBG 10009
gene id: 6238:CBG_10009
uniprot id: A8XA60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 00721
gene id: 6238:CBG_00721
uniprot id: A8WN79
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

6238:CBG 12756
gene id: 6238:CBG_12756
uniprot id: A8XGI1
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

6238:CBG 19177
gene id: 6238:CBG_19177
uniprot id: A8XV05
names: Similarity
messages: Belongs to the UPF0046 family.

6238:CBG 05789
gene id: 6238:CBG_05789
uniprot id: A8X1M4
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 19415
gene id: 6238:CBG_19415
uniprot id: A8XVK2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

6238:CBG 04219
gene id: 6238:CBG_04219
uniprot id: A8WWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

6238:CBG 06913
gene id: 6238:CBG_06913
uniprot id: A8X3C6
names: Similarity
messages: Belongs to the NipSnap family.

6238:CBG 01385
gene id: 6238:CBG_01385
uniprot id: A8WQA4
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 16732
gene id: 6238:CBG_16732
uniprot id: Q612G6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Probable transcription factor. Required for muscle structure. Its dual subcellular localization suggests that it may function both as a muscle adhesion complex protein and as a transcription factor, or work together with transcription factors, to influence gene expression. Thought to act as a molecular bridge between unc-97 and mhc-a at the M-line of muscles, possibly in a signaling role (By similarity).
messages: The N-terminal part (1-106) mediates the nuclear localization, while the fourth zinc finger is required for the localization to M-lines and dense bodies.

6238:CBG 10813
gene id: 6238:CBG_10813
uniprot id: A8XBV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

6238:CBG 22302
gene id: 6238:CBG_22302
uniprot id: A8Y210
names: Similarity
messages: Belongs to the peptidase M24B family.

6238:CBG 13568
gene id: 6238:CBG_13568
uniprot id: A8XI74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRK family.
messages: Interacts with ced-5 (via C-terminus which contains a candidate SH3-binding, proline-rich region). Forms a ternary complex with ced-5 and ced-12. Interacts (via SH-2 domain) with src-1 (when activated and phosphorylated at 'Tyr-416').
messages: Required for cell migration and engulfment of cell corpses but not for programmed cell death/apoptosis. Also has a role in the migration of the 2 gonadal distal tip cells (DTCs) (By similarity).

6238:CBG 04619
gene id: 6238:CBG_04619
uniprot id: A8WY28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

6238:CBG 07651
gene id: 6238:CBG_07651
uniprot id: A8X4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 17647
gene id: 6238:CBG_17647
uniprot id: A8XRM2
names: Similarity
messages: Belongs to the cyclin family.

6238:CBG 00192
gene id: 6238:CBG_00192
uniprot id: A8WMG0
names: Similarity
messages: Belongs to the TAF11 family.

6238:CBG 04534
gene id: 6238:CBG_04534
uniprot id: A8WXN3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 13136
gene id: 6238:CBG_13136
uniprot id: Q61C05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dullard family.
messages: Membrane
messages: Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity).

6238:CBG 20025
gene id: 6238:CBG_20025
uniprot id: A8XWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 16786
gene id: 6238:CBG_16786
uniprot id: Q17299
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Expressed primarily in touch receptor neurons.
messages: Mec-7 beta-tubulin is required for the production of 15-protofilament microtubules.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Plays a role in mechanosensory transduction (touch sensitivity) (By similarity).
messages: cytoskeleton

6238:CBG 00798
gene id: 6238:CBG_00798
uniprot id: A8WNU9
names: Similarity
messages: Belongs to the plant self-incompatibility (S1) protein family.

6238:CBG 00233
gene id: 6238:CBG_00233
uniprot id: A8WMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 18007
gene id: 6238:CBG_18007
uniprot id: A8XST3
names: Similarity
messages: Belongs to the peptidase C2 family.

6238:CBG 12459
gene id: 6238:CBG_12459
uniprot id: A8XFH5
names: Subcellular Location Annotation
messages: Mitochondrion

6238:CBG 15716
gene id: 6238:CBG_15716
uniprot id: A8XML6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

6238:CBG 05338
gene id: 6238:CBG_05338
uniprot id: A8WZM3
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 05833
gene id: 6238:CBG_05833
uniprot id: A8X1I9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

6238:CBG 12343
gene id: 6238:CBG_12343
uniprot id: A8XFL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

6238:CBG 25150
gene id: 6238:CBG_25150
uniprot id: A8WUG5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

6238:CBG 17072
gene id: 6238:CBG_17072
uniprot id: A8XQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 14697
gene id: 6238:CBG_14697
uniprot id: G2J6V0
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 14554
gene id: 6238:CBG_14554
uniprot id: A8XK65
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 19298
gene id: 6238:CBG_19298
uniprot id: A8XVA6
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 16731
gene id: 6238:CBG_16731
uniprot id: A8XPQ1
names: Similarity
messages: Belongs to the apyrase family.

6238:CBG 11921
gene id: 6238:CBG_11921
uniprot id: A8XEL5
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 06102
gene id: 6238:CBG_06102
uniprot id: A8X0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

6238:CBG 13348
gene id: 6238:CBG_13348
uniprot id: A8XHZ5
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

6238:CBG 05259
gene id: 6238:CBG_05259
uniprot id: A8WZH4
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 15773
gene id: 6238:CBG_15773
uniprot id: A8XMR9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

6238:CBG 21269
gene id: 6238:CBG_21269
uniprot id: A8XZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

6238:CBG 02335
gene id: 6238:CBG_02335
uniprot id: A8WUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein srb family.
messages: Membrane

6238:CBG 22344
gene id: 6238:CBG_22344
uniprot id: A8Y271
names: Similarity
messages: Belongs to the UPF0375 family.

6238:CBG 06071
gene id: 6238:CBG_06071
uniprot id: A8X0Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Appears to play a non-essential role (By similarity).
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

6238:CBG 01742
gene id: 6238:CBG_01742
uniprot id: A8WQY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 00142
gene id: 6238:CBG_00142
uniprot id: A8WMD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

6238:CBG 04591
gene id: 6238:CBG_04591
uniprot id: A8WY04
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 18105
gene id: 6238:CBG_18105
uniprot id: A8XT16
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) (By similarity).

6238:CBG 15146
gene id: 6238:CBG_15146
uniprot id: Q616T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL45 family.
messages: Mitochondrion

6238:CBG 10126
gene id: 6238:CBG_10126
uniprot id: Q6E3D0
names: Function
names: Subunit
messages: Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis (By similarity).
messages: Interacts with fbf-1.

6238:CBG 20913
gene id: 6238:CBG_20913
uniprot id: A8XYX9
names: Similarity
messages: Belongs to the nanos family.

6238:CBG 15255
gene id: 6238:CBG_15255
uniprot id: Q616J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim-1. Required for Ca(2+) and IP3-dependent contractile activity of sheath cells and the spermatheca. Affects brood size and somatic cell function (By similarity).
messages: Membrane

6238:CBG 04608
gene id: 6238:CBG_04608
uniprot id: A8WY18
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 22468
gene id: 6238:CBG_22468
uniprot id: A8Y2C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

6238:CBG 21182
gene id: 6238:CBG_21182
uniprot id: A8XZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

6238:CBG 09317
gene id: 6238:CBG_09317
uniprot id: A8X9D8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05113
gene id: 6238:CBG_05113
uniprot id: A8WZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

6238:CBG 20316
gene id: 6238:CBG_20316
uniprot id: A8XXJ0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 14383
gene id: 6238:CBG_14383
uniprot id: A8XJV8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 22133
gene id: 6238:CBG_22133
uniprot id: A8Y1L6
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

6238:CBG 05682
gene id: 6238:CBG_05682
uniprot id: A8X0F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 02540
gene id: 6238:CBG_02540
uniprot id: A8WU31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Autophosphorylates in vitro.
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.
messages: Nucleus
messages: Serine/threonine kinase that phosphorylates baf-1, thus regulating the association of baf-1 with chromatin and nuclear membrane proteins during nuclear envelope formation. May act through the egl-17 signaling pathway. Essential in hermaphrodites for formation of the vulva, uterus, and uterine seam cells and for development and maintenance of the somatic gonad and thus the germ line. Acts to prevent cep-1 from triggering an inappropriate cell cycle arrest, thereby promoting germ cell proliferation. Regulates anchor cell polarity and the timing of anchor cell invasion through the basement membranes separating vulval and somatic gonadal cells during the L3 larval stage (By similarity).

6238:CBG 13501
gene id: 6238:CBG_13501
uniprot id: A8XI15
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

6238:CBG 10453
gene id: 6238:CBG_10453
uniprot id: A8XB92
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

6238:CBG 04158
gene id: 6238:CBG_04158
uniprot id: A8WWA7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 13635
gene id: 6238:CBG_13635
uniprot id: A8XID0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01737
gene id: 6238:CBG_01737
uniprot id: Q623T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: Mitochondrion matrix
messages: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).

6238:CBG 14297
gene id: 6238:CBG_14297
uniprot id: A8XJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

6238:CBG 21918
gene id: 6238:CBG_21918
uniprot id: A8Y183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
messages: Monomer.

6238:CBG 00961
gene id: 6238:CBG_00961
uniprot id: A8WP83
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

6238:CBG 08558
gene id: 6238:CBG_08558
uniprot id: A8X747
names: Similarity
messages: Belongs to the IST1 family.

6238:CBG 04174
gene id: 6238:CBG_04174
uniprot id: A8WWC3
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

6238:CBG 15344
gene id: 6238:CBG_15344
uniprot id: A8XLZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

6238:CBG 06955
gene id: 6238:CBG_06955
uniprot id: A8X421
names: Subcellular Location Annotation
messages: Peroxisome

6238:CBG 18986
gene id: 6238:CBG_18986
uniprot id: Q60WU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function (By similarity).
messages: Part of the SNARE core complex containing CBG09569/SNAP25, snb-1/VAMP2 and CBG03570/STX1A. This complex binds to cpx-1/CPLX1 (By similarity).
messages: synaptic vesicle membrane
messages: synaptosome

6238:CBG 09214
gene id: 6238:CBG_09214
uniprot id: A8X8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

6238:CBG 00666
gene id: 6238:CBG_00666
uniprot id: A8WNC1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

6238:CBG 06858
gene id: 6238:CBG_06858
uniprot id: A8X383
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 02950
gene id: 6238:CBG_02950
uniprot id: A8WT51
names: Similarity
messages: Belongs to the GILT family.

6238:CBG 14904
gene id: 6238:CBG_14904
uniprot id: Q617N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In neurons, required for necrotic cell death by promoting intracellular acidification (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.

6238:CBG 11594
gene id: 6238:CBG_11594
uniprot id: A8XDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

6238:CBG 07415
gene id: 6238:CBG_07415
uniprot id: A8X4T8
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19736
gene id: 6238:CBG_19736
uniprot id: A8XWF8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 04618
gene id: 6238:CBG_04618
uniprot id: A8WY27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

6238:CBG 00359
gene id: 6238:CBG_00359
uniprot id: A8WMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 06882
gene id: 6238:CBG_06882
uniprot id: A8X3A0
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

6238:CBG 13456
gene id: 6238:CBG_13456
uniprot id: A8XHQ3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02671
gene id: 6238:CBG_02671
uniprot id: A8WTS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

6238:CBG 16221
gene id: 6238:CBG_16221
uniprot id: A8XNV3
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

6238:CBG 20903
gene id: 6238:CBG_20903
uniprot id: A8XYX0
names: Similarity
messages: Belongs to the amidase family.

6238:CBG 18008
gene id: 6238:CBG_18008
uniprot id: A8XST4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17053
gene id: 6238:CBG_17053
uniprot id: A8XQC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 04223
gene id: 6238:CBG_04223
uniprot id: A8WWG3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

6238:CBG 22979
gene id: 6238:CBG_22979
uniprot id: Q60MW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPCS3 family.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit sec-11 and three accessory subunits spcs-1, spcs-2 and spcs-3. The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids.
messages: Endoplasmic reticulum membrane
messages: Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface (By similarity).

6238:CBG 09508
gene id: 6238:CBG_09508
uniprot id: A8X8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 07007
gene id: 6238:CBG_07007
uniprot id: A8X3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

6238:CBG 05997
gene id: 6238:CBG_05997
uniprot id: A8X155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 01557
gene id: 6238:CBG_01557
uniprot id: A8WRD5
names: Similarity
messages: Belongs to the amidase family.

6238:CBG 15207
gene id: 6238:CBG_15207
uniprot id: A8XLN9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

6238:CBG 16730
gene id: 6238:CBG_16730
uniprot id: A8XPQ0
names: Similarity
messages: Belongs to the VPS52 family.

6238:CBG 18183
gene id: 6238:CBG_18183
uniprot id: A8XT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

6238:CBG 09664
gene id: 6238:CBG_09664
uniprot id: A8X8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

6238:CBG 18259
gene id: 6238:CBG_18259
uniprot id: A8XS98
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 07973
gene id: 6238:CBG_07973
uniprot id: A8X5H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

6238:CBG 05330
gene id: 6238:CBG_05330
uniprot id: A8WZL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 15641
gene id: 6238:CBG_15641
uniprot id: A8XMF8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 09887
gene id: 6238:CBG_09887
uniprot id: A8X9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

6238:CBG 14935
gene id: 6238:CBG_14935
uniprot id: A8XL15
names: Similarity
messages: Belongs to the maelstrom family.

6238:CBG 19678
gene id: 6238:CBG_19678
uniprot id: A8XW63
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

6238:CBG 13573
gene id: 6238:CBG_13573
uniprot id: A8XI77
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

6238:CBG 24280
gene id: 6238:CBG_24280
uniprot id: A8WKD3
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

6238:CBG 11404
gene id: 6238:CBG_11404
uniprot id: A8XD39
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 11960
gene id: 6238:CBG_11960
uniprot id: A8XEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

6238:CBG 10030
gene id: 6238:CBG_10030
uniprot id: A8XA78
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

6238:CBG 15713
gene id: 6238:CBG_15713
uniprot id: A8XML3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

6238:CBG 15066
gene id: 6238:CBG_15066
uniprot id: A8XLB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Membrane

6238:CBG 07873
gene id: 6238:CBG_07873
uniprot id: A8X5B6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 08034
gene id: 6238:CBG_08034
uniprot id: A8X5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

6238:CBG 20640
gene id: 6238:CBG_20640
uniprot id: A8XY98
names: Similarity
messages: Belongs to the glutamine synthetase family.

6238:CBG 12721
gene id: 6238:CBG_12721
uniprot id: A8XGF1
names: Cofactor
messages: Binds 2 iron ions per subunit.

6238:CBG 09982
gene id: 6238:CBG_09982
uniprot id: A8XA35
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 10069
gene id: 6238:CBG_10069
uniprot id: A8XAB1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 20595
gene id: 6238:CBG_20595
uniprot id: A8XY60
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 21369
gene id: 6238:CBG_21369
uniprot id: A8XZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

6238:CBG 23424
gene id: 6238:CBG_23424
uniprot id: A8Y3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 00999
gene id: 6238:CBG_00999
uniprot id: A8WP50
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06035
gene id: 6238:CBG_06035
uniprot id: A8X120
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 04460
gene id: 6238:CBG_04460
uniprot id: A8WXM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Cytoplasm
messages: Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate. Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA. May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells.
messages: The conserved active site Tyr residue in position 221 is replaced by a Phe.

6238:CBG 24065
gene id: 6238:CBG_24065
uniprot id: G2J698
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 00535
gene id: 6238:CBG_00535
uniprot id: A8WNN5
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 08658
gene id: 6238:CBG_08658
uniprot id: A8X6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

6238:CBG 05778
gene id: 6238:CBG_05778
uniprot id: A8X1N2
names: Similarity
messages: Belongs to the BLOC1S5 family.

6238:CBG 05841
gene id: 6238:CBG_05841
uniprot id: A8X1I1
names: Similarity
messages: Belongs to the histone H3 family.

6238:CBG 22835
gene id: 6238:CBG_22835
uniprot id: A8Y360
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 05009
gene id: 6238:CBG_05009
uniprot id: A8WYZ1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 18087
gene id: 6238:CBG_18087
uniprot id: Q60YU0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

6238:CBG 15465
gene id: 6238:CBG_15465
uniprot id: A8XM86
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

6238:CBG 08614
gene id: 6238:CBG_08614
uniprot id: A8X6Z7
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

6238:CBG 19506
gene id: 6238:CBG_19506
uniprot id: A8XVS0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 21173
gene id: 6238:CBG_21173
uniprot id: A8XZB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

6238:CBG 22274
gene id: 6238:CBG_22274
uniprot id: A8Y1Y5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

6238:CBG 03324
gene id: 6238:CBG_03324
uniprot id: A8WUS4
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

6238:CBG 13738
gene id: 6238:CBG_13738
uniprot id: A8XIK7
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 15645
gene id: 6238:CBG_15645
uniprot id: A8XMG2
names: Similarity
messages: Belongs to the GCN1 family.

6238:CBG 07870
gene id: 6238:CBG_07870
uniprot id: A8X5B4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 20553
gene id: 6238:CBG_20553
uniprot id: A8XY26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 00560
gene id: 6238:CBG_00560
uniprot id: A8WNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 07042
gene id: 6238:CBG_07042
uniprot id: A8X3U6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23255
gene id: 6238:CBG_23255
uniprot id: A8Y4C6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 02040
gene id: 6238:CBG_02040
uniprot id: A8WRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

6238:CBG 19695
gene id: 6238:CBG_19695
uniprot id: Q60V51
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
messages: Required for branched chain fatty acid synthesis. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. Very long-chain fatty acids (VLCFAs) serve as precursors for ceramide and sphingolipids. May also be required for sterol hormone production (By similarity).

6238:CBG 21508
gene id: 6238:CBG_21508
uniprot id: A8Y0A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

6238:CBG 23146
gene id: 6238:CBG_23146
uniprot id: A8Y4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

6238:CBG 10568
gene id: 6238:CBG_10568
uniprot id: A8XBC4
names: Similarity
messages: Belongs to the ATG101 family.

6238:CBG 17085
gene id: 6238:CBG_17085
uniprot id: A8XQF1
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 08819
gene id: 6238:CBG_08819
uniprot id: A8X7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

6238:CBG 19704
gene id: 6238:CBG_19704
uniprot id: Q60V43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 13393
gene id: 6238:CBG_13393
uniprot id: A8XHV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

6238:CBG 12349
gene id: 6238:CBG_12349
uniprot id: A8XFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

6238:CBG 13185
gene id: 6238:CBG_13185
uniprot id: A8XH91
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02871
gene id: 6238:CBG_02871
uniprot id: A8WTB8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 17475
gene id: 6238:CBG_17475
uniprot id: A8XR41
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 08181
gene id: 6238:CBG_08181
uniprot id: A8X604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

6238:CBG 23436
gene id: 6238:CBG_23436
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 23372
gene id: 6238:CBG_23372
uniprot id: A8Y428
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 04073
gene id: 6238:CBG_04073
uniprot id: A8WW53
names: Similarity
messages: Belongs to the TBCD family.

6238:CBG 09391
gene id: 6238:CBG_09391
uniprot id: Q67EQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

6238:CBG 14895
gene id: 6238:CBG_14895
uniprot id: A8XKX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 06541
gene id: 6238:CBG_06541
uniprot id: A8X2H3
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 17350
gene id: 6238:CBG_17350
uniprot id: A8XQV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane

6238:CBG 17899
gene id: 6238:CBG_17899
uniprot id: A8XS22
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 07004
gene id: 6238:CBG_07004
uniprot id: A8X3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 20737
gene id: 6238:CBG_20737
uniprot id: A8XYH6
names: Similarity
messages: Belongs to the glutamine synthetase family.

6238:CBG 14386
gene id: 6238:CBG_14386
uniprot id: A8XJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

6238:CBG 14137
gene id: 6238:CBG_14137
uniprot id: P32809
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

6238:CBG 05809
gene id: 6238:CBG_05809
uniprot id: A8X1K7
names: Similarity
messages: Belongs to the globin family.

6238:CBG 03131
gene id: 6238:CBG_03131
uniprot id: Q61ZF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat G protein beta family.
messages: G proteins are composed of 3 units, alpha, beta and gamma. Interacts with G protein gamma subunits gpc-1 and gpc-2 and with egl-10 and eat-16. Interacts with goa-1 (in GDP-bound form).
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces.

6238:CBG 16653
gene id: 6238:CBG_16653
uniprot id: A8XP85
names: Similarity
messages: Belongs to the patched family.

6238:CBG 23190
gene id: 6238:CBG_23190
uniprot id: A8Y4H5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 19878
gene id: 6238:CBG_19878
uniprot id: A8XWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
messages: Secreted

6238:CBG 18786
gene id: 6238:CBG_18786
uniprot id: A8XU42
names: Similarity
messages: Belongs to the importin alpha family.

6238:CBG 22996
gene id: 6238:CBG_22996
uniprot id: A8Y3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 13718
gene id: 6238:CBG_13718
uniprot id: A8XIJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 18435
gene id: 6238:CBG_18435
uniprot id: A8XTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

6238:CBG 03013
gene id: 6238:CBG_03013
uniprot id: A8WSZ9
names: Similarity
messages: Belongs to the SLBP family.

6238:CBG 12250
gene id: 6238:CBG_12250
uniprot id: A8XF34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

6238:CBG 06060
gene id: 6238:CBG_06060
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 20198
gene id: 6238:CBG_20198
uniprot id: A8XX79
names: Similarity
messages: Belongs to the histone H3 family.

6238:CBG 01375
gene id: 6238:CBG_01375
uniprot id: A8WQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

6238:CBG 23231
gene id: 6238:CBG_23231
uniprot id: A8Y4E5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 14077
gene id: 6238:CBG_14077
uniprot id: A8XJA7
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 04354
gene id: 6238:CBG_04354
uniprot id: A8WXC2
names: Similarity
messages: Belongs to the peptidase M13 family.

6238:CBG 06503
gene id: 6238:CBG_06503
uniprot id: A8X2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 19214
gene id: 6238:CBG_19214
uniprot id: A8XV35
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 23568
gene id: 6238:CBG_23568
uniprot id: A8WIU9
names: Similarity
messages: Belongs to the UQCRB/QCR7 family.

6238:CBG 20871
gene id: 6238:CBG_20871
uniprot id: A8XYU4
names: Similarity
messages: Belongs to the BORA family.

6238:CBG 09944
gene id: 6238:CBG_09944
uniprot id: A8XA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 10645
gene id: 6238:CBG_10645
uniprot id: A8XBI4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

6238:CBG 13670
gene id: 6238:CBG_13670
uniprot id: A8XIG1
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

6238:CBG 10109
gene id: 6238:CBG_10109
uniprot id: A8XAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 12067
gene id: 6238:CBG_12067
uniprot id: A8XEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 16268
gene id: 6238:CBG_16268
uniprot id: A8XNS2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

6238:CBG 00121
gene id: 6238:CBG_00121
uniprot id: A8WMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

6238:CBG 21868
gene id: 6238:CBG_21868
uniprot id: A8Y108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

6238:CBG 03310
gene id: 6238:CBG_03310
uniprot id: A8WSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 16409
gene id: 6238:CBG_16409
uniprot id: A8XNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 13259
gene id: 6238:CBG_13259
uniprot id: A8XHF1
names: Similarity
messages: Belongs to the STEEP1 family.

6238:CBG 08575
gene id: 6238:CBG_08575
uniprot id: A8X733
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 09126
gene id: 6238:CBG_09126
uniprot id: A8X855
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 03939
gene id: 6238:CBG_03939
uniprot id: A8WVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

6238:CBG 08648
gene id: 6238:CBG_08648
uniprot id: A8X6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Cell membrane
messages: Mediates sugar transport across membranes.
messages: Membrane

6238:CBG 04294
gene id: 6238:CBG_04294
uniprot id: A8WX64
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

6238:CBG 04280
gene id: 6238:CBG_04280
uniprot id: A8WX49
names: Similarity
messages: Belongs to the peptidase S10 family.

6238:CBG 17000
gene id: 6238:CBG_17000
uniprot id: A8XQ85
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 04105
gene id: 6238:CBG_04105
uniprot id: A8WW81
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 06836
gene id: 6238:CBG_06836
uniprot id: A8X367
names: Similarity
messages: Belongs to the peptidase C48 family.

6238:CBG 09633
gene id: 6238:CBG_09633
uniprot id: A8X8L7
names: Similarity
messages: Belongs to the PP2C family.

6238:CBG 12936
gene id: 6238:CBG_12936
uniprot id: A8XGQ3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 03442
gene id: 6238:CBG_03442
uniprot id: A8WV28
names: Similarity
messages: Belongs to the RRP1 family.

6238:CBG 05355
gene id: 6238:CBG_05355
uniprot id: P35074
names: Domain
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Chromosome
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. Interacts with sig-7.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Involved in the transcription of several genes including those involved in embryogenesis.
messages: Following transcription stress, the elongating form of RNA polymerase II (RNA pol IIo) is polyubiquitinated via 'Lys-63'-linkages on Lys-1260 at DNA damage sites without leading to degradation: ubiquitination promotes RNA pol IIo backtracking to allow access by the transcription-coupled nucleotide excision repair (TC-NER) machinery. Subsequent DEF1-dependent polyubiquitination by the elongin complex via 'Lys-48'-linkages may lead to proteasome-mediated degradation; presumably at stalled RNA pol II where TC-NER has failed, to halt global transcription and enable 'last resort' DNA repair pathways.
messages: Nucleus
messages: The C-terminal domain (CTD) serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing.
messages: The binding of ribonucleoside triphosphate to the RNA polymerase II transcribing complex probably involves a two-step mechanism. The initial binding seems to occur at the entry (E) site and involves a magnesium ion temporarily coordinated by three conserved aspartate residues of the two largest RNA Pol II subunits. The ribonucleoside triphosphate is transferred by a rotation to the nucleotide addition (A) site for pairing with the template DNA. The catalytic A site involves three conserved aspartate residues of the RNA Pol II largest subunit which permanently coordinate a second magnesium ion.
messages: The tandem 7 residues repeats in the C-terminal domain (CTD) can be highly phosphorylated. The phosphorylation activates Pol II. Phosphorylation occurs mainly at residues 'Ser-2' and 'Ser-5' of the heptapeptide repeat and starts at the 3- to 4-cell embryonic stage. This phosphorylation also occurs in the early stages of oocyte development and is not detected in oocytes arrested at the meiotic diakinesis stage. In the somatic lineage, phosphorylation at 'Ser-2' is mediated by cdk-12 downstream of cdk-9 whereas in the germline lineage cdk-12 phosphorylates 'Ser-2' independently of cdk-9. Phosphorylation is likely mediated by cdk-7. May be dephosphorylated by fcp-1 in diakinetic oocytes and in 1-cell and 2-cell embryos. Dephosphorylated at 'Ser-5' of the heptapeptide repeat by ssup-72. The phosphorylation state is believed to result from the balanced action of site-specific CTD kinases and phosphatase, and a 'CTD code' that specifies the position of Pol II within the transcription cycle has been proposed.

6238:CBG 20329
gene id: 6238:CBG_20329
uniprot id: A8XXJ9
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 12003
gene id: 6238:CBG_12003
uniprot id: A8XEB6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

6238:CBG 13395
gene id: 6238:CBG_13395
uniprot id: A8XHV3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

6238:CBG 02884
gene id: 6238:CBG_02884
uniprot id: Q620A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly.
messages: Mitochondrion inner membrane

6238:CBG 17759
gene id: 6238:CBG_17759
uniprot id: A8XRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

6238:CBG 19646
gene id: 6238:CBG_19646
uniprot id: G2J700
names: Similarity
messages: Belongs to the BACURD family.

6238:CBG 02970
gene id: 6238:CBG_02970
uniprot id: A8WT32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

6238:CBG 18950
gene id: 6238:CBG_18950
uniprot id: A8XUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Endoplasmic reticulum membrane

6238:CBG 01313
gene id: 6238:CBG_01313
uniprot id: A8WQ42
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

6238:CBG 19337
gene id: 6238:CBG_19337
uniprot id: A8XVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

6238:CBG 13540
gene id: 6238:CBG_13540
uniprot id: A8XI50
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

6238:CBG 19003
gene id: 6238:CBG_19003
uniprot id: A8XUJ7
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03898
gene id: 6238:CBG_03898
uniprot id: A8WVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

6238:CBG 23090
gene id: 6238:CBG_23090
uniprot id: A8Y4R0
names: Similarity
messages: Belongs to the actin family.

6238:CBG 10950
gene id: 6238:CBG_10950
uniprot id: A8XBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 21205
gene id: 6238:CBG_21205
uniprot id: A8XZL7
names: Similarity
messages: Belongs to the MIP18 family.

6238:CBG 01975
gene id: 6238:CBG_01975
uniprot id: A8WRQ4
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

6238:CBG 11538
gene id: 6238:CBG_11538
uniprot id: Q61FQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIA30 family.
messages: Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Required for normal growth and reproduction (By similarity).
messages: Mitochondrion

6238:CBG 13880
gene id: 6238:CBG_13880
uniprot id: A8XJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

6238:CBG 04756
gene id: 6238:CBG_04756
uniprot id: A8WYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Phosphorylates and restricts the asymmetry effector mex-5 (and possibly also mex-6) to the anterior cytoplasm of the zygote. Regulates mes-1 expression during early embryogenesis. Critical role in postembryonic vulval morphogenesis.
messages: cell cortex

6238:CBG 04558
gene id: 6238:CBG_04558
uniprot id: A8WXX4
names: Similarity
messages: Belongs to the kindlin family.

6238:CBG 20332
gene id: 6238:CBG_20332
uniprot id: A8XXK1
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 05747
gene id: 6238:CBG_05747
uniprot id: A8X1Q8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

6238:CBG 20962
gene id: 6238:CBG_20962
uniprot id: A8XZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 09395
gene id: 6238:CBG_09395
uniprot id: A8X970
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 05461
gene id: 6238:CBG_05461
uniprot id: A8WZX6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13375
gene id: 6238:CBG_13375
uniprot id: A8XHX1
names: Similarity
messages: Belongs to the TTC36 family.

6238:CBG 01507
gene id: 6238:CBG_01507
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 19475
gene id: 6238:CBG_19475
uniprot id: A8XVM8
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

6238:CBG 05840
gene id: 6238:CBG_05840
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 23048
gene id: 6238:CBG_23048
uniprot id: A8Y3D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

6238:CBG 17998
gene id: 6238:CBG_17998
uniprot id: A8XSS5
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.

6238:CBG 20902
gene id: 6238:CBG_20902
uniprot id: A8XYW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
messages: nucleolus
messages: nucleoplasm

6238:CBG 01661
gene id: 6238:CBG_01661
uniprot id: A8WR51
names: Similarity
messages: Belongs to the isochorismatase family.

6238:CBG 16397
gene id: 6238:CBG_16397
uniprot id: A8XNJ0
names: Similarity
messages: Belongs to the NDRG family.

6238:CBG 03774
gene id: 6238:CBG_03774
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 15876
gene id: 6238:CBG_15876
uniprot id: A8XMU3
names: Similarity
messages: Belongs to the FAX family.

6238:CBG 22728
gene id: 6238:CBG_22728
uniprot id: A8Y315
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

6238:CBG 15755
gene id: 6238:CBG_15755
uniprot id: A8XMQ1
names: Similarity
messages: Belongs to the group II decarboxylase family.

6238:CBG 14675
gene id: 6238:CBG_14675
uniprot id: Q618G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family.
messages: Membrane
messages: Probable sterol desaturase.

6238:CBG 12934
gene id: 6238:CBG_12934
uniprot id: A8XGQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.

6238:CBG 08994
gene id: 6238:CBG_08994
uniprot id: A8X822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

6238:CBG 22709
gene id: 6238:CBG_22709
uniprot id: A8Y300
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

6238:CBG 05897
gene id: 6238:CBG_05897
uniprot id: A8X1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Nucleus

6238:CBG 00425
gene id: 6238:CBG_00425
uniprot id: A8WN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

6238:CBG 12227
gene id: 6238:CBG_12227
uniprot id: A8XEY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 04218
gene id: 6238:CBG_04218
uniprot id: A8WWF9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

6238:CBG 23306
gene id: 6238:CBG_23306
uniprot id: Q60M48
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with sas-6 via its coiled coil domain.
messages: Required for centrosome duplication. Essential for daughter-centriole formation. Requires both maternal and partenal expression, suggesting that it regulates centriole duplication during both spermatogenesis and early embryogenesis (By similarity).
messages: centriole

6238:CBG 10097
gene id: 6238:CBG_10097
uniprot id: A8XAD8
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

6238:CBG 08840
gene id: 6238:CBG_08840
uniprot id: A8X7I3
names: Similarity
messages: Belongs to the annexin family.

6238:CBG 08738
gene id: 6238:CBG_08738
uniprot id: A8X798
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 06591
gene id: 6238:CBG_06591
uniprot id: A8X2L4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 00558
gene id: 6238:CBG_00558
uniprot id: A8WNL3
names: Similarity
messages: Belongs to the KRI1 family.

6238:CBG 23916
gene id: 6238:CBG_23916
uniprot id: A8WJK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 17724
gene id: 6238:CBG_17724
uniprot id: Q60ZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sidekick family.
messages: Cell adhesion protein.
messages: Membrane

6238:CBG 18031
gene id: 6238:CBG_18031
uniprot id: A8XSV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

6238:CBG 19656
gene id: 6238:CBG_19656
uniprot id: A8XW44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

6238:CBG 19952
gene id: 6238:CBG_19952
uniprot id: A8XWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 02945
gene id: 6238:CBG_02945
uniprot id: A8WT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

6238:CBG 05118
gene id: 6238:CBG_05118
uniprot id: A8WZ78
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02622
gene id: 6238:CBG_02622
uniprot id: A8WTW4
names: Similarity
messages: Belongs to the globin family.

6238:CBG 19304
gene id: 6238:CBG_19304
uniprot id: A8XVB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 10037
gene id: 6238:CBG_10037
uniprot id: A8XA84
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 19292
gene id: 6238:CBG_19292
uniprot id: A8XVA0
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

6238:CBG 05963
gene id: 6238:CBG_05963
uniprot id: A8X181
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fic family.
messages: Endoplasmic reticulum membrane
messages: Forms homodimers; homodimerization might be required for adenylyltransferase activity.
messages: Nucleus membrane
messages: Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context (By similarity). The side chain of Glu-273 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place (By similarity). Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. In vivo target proteins include the heat-shock 70 family proteins hsp-1 and hsp-3 and the translation elongation factors eef-1A, eef-1G and eef-2. Can AMPylate core histone H3 in vitro (By similarity). Can also act as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from target proteins (By similarity). Decreases susceptibility to P.aeruginosa-mediated killing and might therefore play a role in the innate immune response (By similarity).
messages: The fido domain mediates the adenylyltransferase activity.
messages: The side chain of Glu-273 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place. In response to endoplasmic reticulum stress, mediates de-AMPylase activity (By similarity). Adenylyltransferase activity is inhibited by the inhibitory helix present at the N-terminus: Glu-273 binds ATP and competes with ATP-binding at Arg-414, thereby preventing adenylyltransferase activity (By similarity). In unstressed cells, disengagement of Glu-273 promotes adenylyltransferase activity (By similarity). Activation dissociates ATP-binding from Glu-273, allowing ordered binding of the entire ATP moiety with the alpha-phosphate in an orientation that is productive for accepting an incoming target hydroxyl side chain (By similarity).

6238:CBG 12026
gene id: 6238:CBG_12026
uniprot id: A8XED8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

6238:CBG 01668
gene id: 6238:CBG_01668
uniprot id: A8WR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

6238:CBG 03634
gene id: 6238:CBG_03634
uniprot id: A8WVH5
names: Similarity
messages: Belongs to the RRN3 family.

6238:CBG 07909
gene id: 6238:CBG_07909
uniprot id: A8X562
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

6238:CBG 08892
gene id: 6238:CBG_08892
uniprot id: A8X7M4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10413
gene id: 6238:CBG_10413
uniprot id: A8XB54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 21202
gene id: 6238:CBG_21202
uniprot id: A8XZM0
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 12563
gene id: 6238:CBG_12563
uniprot id: Q61DA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.
messages: Mitochondrion

6238:CBG 09482
gene id: 6238:CBG_09482
uniprot id: A8X905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
messages: Secreted

6238:CBG 22043
gene id: 6238:CBG_22043
uniprot id: A8Y1E5
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

6238:CBG 23229
gene id: 6238:CBG_23229
uniprot id: A8Y4E7
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.

6238:CBG 05511
gene id: 6238:CBG_05511
uniprot id: A8X020
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the queuosine salvage protein family.
messages: Cytoplasm
messages: Involved in salvaging queuosine.

6238:CBG 23705
gene id: 6238:CBG_23705
uniprot id: A8WJ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: May be required for cytochrome c complex (COX) assembly and function, COX being the terminal component of the mitochondrial respiratory chain.
messages: Mitochondrion inner membrane

6238:CBG 23368
gene id: 6238:CBG_23368
uniprot id: A8Y432
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Membrane
messages: Mitochondrion

6238:CBG 10410
gene id: 6238:CBG_10410
uniprot id: A8XB52
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

6238:CBG 06851
gene id: 6238:CBG_06851
uniprot id: A8X379
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S9 family.
messages: Component of the lid subcomplex of the 19S proteasome regulatory particle complex (also named PA700 complex). The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits (By similarity).
messages: Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.2 is required for proteasome assembly (By similarity).

6238:CBG 10084
gene id: 6238:CBG_10084
uniprot id: A8XAC6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BAF family.
messages: DNA-binding protein which plays an essential role in nuclear envelope formation. Required for normal chromosome segregation during mitosis. Associates with the nuclear lamina via its interaction with LEM domain containing proteins emr-1 and lem-2 (By similarity).
messages: Interacts with emr-1 and lem-2. Interacts with lem-4l, leading to decreased phosphorylation by VRK1 and promoting dephosphorylation by protein phosphatase 2A (PP2A) (By similarity).
messages: Nucleus
messages: Phosphorylated by vrk-1. Phosphorylation by vrk-1 in mitosis is essential to achieve correct timing of recruitment of nuclear envelope components during nuclear envelope assembly. Dephosphorylated by protein phosphatase 2A (PP2A) following interaction with lem-4l during mitotic exit, leading to mitotic nuclear envelope reassembly (By similarity).

6238:CBG 09584
gene id: 6238:CBG_09584
uniprot id: A8X8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity).

6238:CBG 04201
gene id: 6238:CBG_04201
uniprot id: A8WWE8
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

6238:CBG 08350
gene id: 6238:CBG_08350
uniprot id: A8X6D0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

6238:CBG 11892
gene id: 6238:CBG_11892
uniprot id: A8XE89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 13148
gene id: 6238:CBG_13148
uniprot id: A8XH63
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

6238:CBG 13454
gene id: 6238:CBG_13454
uniprot id: A8XHQ6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02944
gene id: 6238:CBG_02944
uniprot id: A8WT56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 14670
gene id: 6238:CBG_14670
uniprot id: A8XKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

6238:CBG 09411
gene id: 6238:CBG_09411
uniprot id: A8X959
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 08188
gene id: 6238:CBG_08188
uniprot id: A8X610
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

6238:CBG 17938
gene id: 6238:CBG_17938
uniprot id: A8XRY3
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06237
gene id: 6238:CBG_06237
uniprot id: A8X0K4
names: Similarity
messages: Belongs to the uridine kinase family.

6238:CBG 23471
gene id: 6238:CBG_23471
uniprot id: A8Y3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 09828
gene id: 6238:CBG_09828
uniprot id: A8X9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

6238:CBG 08367
gene id: 6238:CBG_08367
uniprot id: A8X6E3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 22375
gene id: 6238:CBG_22375
uniprot id: A8Y238
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

6238:CBG 18338
gene id: 6238:CBG_18338
uniprot id: A8XSG9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

6238:CBG 07717
gene id: 6238:CBG_07717
uniprot id: A8X481
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Regulates pharyngeal pumping during feeding.

6238:CBG 20786
gene id: 6238:CBG_20786
uniprot id: E3CU83
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

6238:CBG 17978
gene id: 6238:CBG_17978
uniprot id: Q60Z38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cytoplasm

6238:CBG 00598
gene id: 6238:CBG_00598
uniprot id: Q627N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Nucleus
messages: Serine/threonine-protein phosphatase essential for chromosomal dynamics during meiosis and mitosis. Antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Essential for embryogenesis (By similarity).

6238:CBG 23452
gene id: 6238:CBG_23452
uniprot id: A8Y3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

6238:CBG 00365
gene id: 6238:CBG_00365
uniprot id: A8WMX2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18938
gene id: 6238:CBG_18938
uniprot id: A8XUE2
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

6238:CBG 08694
gene id: 6238:CBG_08694
uniprot id: A8X6S6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10328
gene id: 6238:CBG_10328
uniprot id: A8XAK9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 16184
gene id: 6238:CBG_16184
uniprot id: A8XNX7
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 08285
gene id: 6238:CBG_08285
uniprot id: A8X676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 12986
gene id: 6238:CBG_12986
uniprot id: A8XGU2
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 17984
gene id: 6238:CBG_17984
uniprot id: A8XSR2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 23152
gene id: 6238:CBG_23152
uniprot id: A8Y4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 14201
gene id: 6238:CBG_14201
uniprot id: A8XJI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

6238:CBG 20711
gene id: 6238:CBG_20711
uniprot id: A8XYF8
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 12062
gene id: 6238:CBG_12062
uniprot id: A8XEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

6238:CBG 03751
gene id: 6238:CBG_03751
uniprot id: A8WWM4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

6238:CBG 24657
gene id: 6238:CBG_24657
uniprot id: A8WL66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 21548
gene id: 6238:CBG_21548
uniprot id: A8Y0C9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 06116
gene id: 6238:CBG_06116
uniprot id: A8X0V4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

6238:CBG 05212
gene id: 6238:CBG_05212
uniprot id: A8WZE4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 15261
gene id: 6238:CBG_15261
uniprot id: A8XLJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 21344
gene id: 6238:CBG_21344
uniprot id: A8XZW0
names: Similarity
messages: Belongs to the RRP7 family.

6238:CBG 00499
gene id: 6238:CBG_00499
uniprot id: A8WMT4
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

6238:CBG 08474
gene id: 6238:CBG_08474
uniprot id: A8X6M9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 23384
gene id: 6238:CBG_23384
uniprot id: A8Y418
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

6238:CBG 12468
gene id: 6238:CBG_12468
uniprot id: A8XFI3
names: Similarity
messages: Belongs to the histone H3 family.

6238:CBG 04825
gene id: 6238:CBG_04825
uniprot id: A8WYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 09010
gene id: 6238:CBG_09010
uniprot id: A8X808
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 04602
gene id: 6238:CBG_04602
uniprot id: A8WY12
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 20050
gene id: 6238:CBG_20050
uniprot id: A8XX02
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 19793
gene id: 6238:CBG_19793
uniprot id: H8WHA8
uniprot id: Q60UW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: Cytoplasm
messages: The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
messages: Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. Involved in muscle actin filament organization and muscle arm extension and morphology. Also has a role in male mating behavior by regulating the copulatory spicules. Binds to F-actin (By similarity).

6238:CBG 10154
gene id: 6238:CBG_10154
uniprot id: A8XAI1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

6238:CBG 19435
gene id: 6238:CBG_19435
uniprot id: A8XVM0
names: Similarity
messages: Belongs to the DeSI family.

6238:CBG 19690
gene id: 6238:CBG_19690
uniprot id: A8XW75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

6238:CBG 09068
gene id: 6238:CBG_09068
uniprot id: A8X7V7
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

6238:CBG 11891
gene id: 6238:CBG_11891
uniprot id: A8XE88
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23335
gene id: 6238:CBG_23335
uniprot id: A0T399
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer of burs and pburs.
messages: Secreted

6238:CBG 21347
gene id: 6238:CBG_21347
uniprot id: A8XZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

6238:CBG 13686
gene id: 6238:CBG_13686
uniprot id: A8XIH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

6238:CBG 13851
gene id: 6238:CBG_13851
uniprot id: A8XIV0
names: Similarity
messages: Belongs to the isochorismatase family.

6238:CBG 17658
gene id: 6238:CBG_17658
uniprot id: A8XRL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

6238:CBG 04041
gene id: 6238:CBG_04041
uniprot id: A8WW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

6238:CBG 19191
gene id: 6238:CBG_19191
uniprot id: A8XV16
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 10989
gene id: 6238:CBG_10989
uniprot id: A8XC00
names: Similarity
messages: Belongs to the SKP1 family.

6238:CBG 09864
gene id: 6238:CBG_09864
uniprot id: A8X9U6
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

6238:CBG 06731
gene id: 6238:CBG_06731
uniprot id: A8X2Y9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12014
gene id: 6238:CBG_12014
uniprot id: A8XEC6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

6238:CBG 13576
gene id: 6238:CBG_13576
uniprot id: A8XI80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 03882
gene id: 6238:CBG_03882
uniprot id: A8WX00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

6238:CBG 11380
gene id: 6238:CBG_11380
uniprot id: A8XD55
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 12150
gene id: 6238:CBG_12150
uniprot id: A8XEV4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

6238:CBG 02964
gene id: 6238:CBG_02964
uniprot id: A8WT36
names: Similarity
messages: Belongs to the APC1 family.

6238:CBG 02803
gene id: 6238:CBG_02803
uniprot id: A8WTH1
names: Similarity
messages: Belongs to the BACURD family.

6238:CBG 12500
gene id: 6238:CBG_12500
uniprot id: A8XFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

6238:CBG 07988
gene id: 6238:CBG_07988
uniprot id: A8X5I5
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

6238:CBG 11178
gene id: 6238:CBG_11178
uniprot id: A8XCM4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

6238:CBG 23799
gene id: 6238:CBG_23799
uniprot id: A8WJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: centriolar satellite
messages: cilium membrane

6238:CBG 01222
gene id: 6238:CBG_01222
uniprot id: A8WPV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 03907
gene id: 6238:CBG_03907
uniprot id: A8WVQ3
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13493
gene id: 6238:CBG_13493
uniprot id: A8XI08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

6238:CBG 22969
gene id: 6238:CBG_22969
uniprot id: A8Y3J7
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

6238:CBG 20153
gene id: 6238:CBG_20153
uniprot id: A8XXB0
names: Similarity
messages: Belongs to the NSRP1 family.

6238:CBG 00805
gene id: 6238:CBG_00805
uniprot id: A8WNV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

6238:CBG 03741
gene id: 6238:CBG_03741
uniprot id: A8WWL8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

6238:CBG 07481
gene id: 6238:CBG_07481
uniprot id: A8X4P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

6238:CBG 20982
gene id: 6238:CBG_20982
uniprot id: E3CU86
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 22997
gene id: 6238:CBG_22997
uniprot id: A8Y3H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Transfers N-acetylgalactosamine onto carbohydrate substrates. Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-3, bre-4, and bre-5. Involved in resistance to the nematotoxic C.cinerea galectin Cgl2.

6238:CBG 10035
gene id: 6238:CBG_10035
uniprot id: A8XA82
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

6238:CBG 02667
gene id: 6238:CBG_02667
uniprot id: A8WTS8
names: Similarity
messages: Belongs to the cuticular collagen family.

6238:CBG 22936
gene id: 6238:CBG_22936
uniprot id: A8Y3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins such as unc-5 and mig-21. Mediates the attachment of alpha-mannose in C-C linkage to the C2 of the indole ring of tryptophan. C-mannosylation takes place in the endoplasmic reticulum and frequently found in thrombospondin (TSP) type-1 repeats and in the WSXWS motif of type I cytokine receptors. Required to orient neuroblasts QL and QR correctly on the anterior/posterior (A/P) axis: QL and QR are born in the same A/P position, but polarize and migrate left/right asymmetrically, QL migrates toward the posterior and QR migrates toward the anterior. Required with unc-40 to express mab-5 correctly in the Q cell descendants (By similarity).
messages: Endoplasmic reticulum membrane

6238:CBG 01576
gene id: 6238:CBG_01576
uniprot id: A8WRC1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

6238:CBG 03530
gene id: 6238:CBG_03530
uniprot id: A8WV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 09753
gene id: 6238:CBG_09753
uniprot id: Q61JK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP20 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility.
messages: Nucleus
messages: centriole
messages: cilium axoneme
messages: cilium basal body

6238:CBG 14296
gene id: 6238:CBG_14296
uniprot id: A8XJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 17074
gene id: 6238:CBG_17074
uniprot id: A8XQF8
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 14059
gene id: 6238:CBG_14059
uniprot id: A8XJ98
names: Developmental Stage
names: Function
names: Subcellular Location Annotation
messages: Expressed in 1.5-fold stage embryos, in developing pharynx and at lower levels in hypodermal cells and the hindgut (at protein level).
messages: Nucleus
messages: Putative transcription factor. Binds to specific sequence motif 5'-[TC][AGT]TGCC[GA][AT]-3' in regulatory elements of target genes such as myosin myo-2. May modulate gene expression, perhaps acting in opposition to transcription factor pha-4. Involved in morphogenesis, perhaps especially in formation of the pharynx. Plays roles in molting, feeding and morphology.

6238:CBG 00257
gene id: 6238:CBG_00257
uniprot id: A8WMK4
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

6238:CBG 22510
gene id: 6238:CBG_22510
uniprot id: A8Y2F7
names: Similarity
messages: Belongs to the SHQ1 family.
messages: Belongs to the peptidase C48 family.

6238:CBG 18162
gene id: 6238:CBG_18162
uniprot id: Q60YN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-117' of histone H2B (By similarity). H2B 'Lys-117' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (By similarity). Involved in regulating stem cell proliferative fate (By similarity).
messages: Interacts with ubc-1 (By similarity). Interacts with mrg-1 (By similarity).
messages: Nucleus

6238:CBG 19635
gene id: 6238:CBG_19635
uniprot id: A8XW26
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

6238:CBG 19289
gene id: 6238:CBG_19289
uniprot id: A8XV98
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 11996
gene id: 6238:CBG_11996
uniprot id: A8XEB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 20456
gene id: 6238:CBG_20456
uniprot id: Q60TI7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: The thioether cross-link between Cys-85 and Tyr-149 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen.

6238:CBG 08882
gene id: 6238:CBG_08882
uniprot id: A8X7L9
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

6238:CBG 02865
gene id: 6238:CBG_02865
uniprot id: A8WTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Peroxisome

6238:CBG 19080
gene id: 6238:CBG_19080
uniprot id: A8XUR1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20584
gene id: 6238:CBG_20584
uniprot id: A8XY51
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 06032
gene id: 6238:CBG_06032
uniprot id: A8X122
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

6238:CBG 03678
gene id: 6238:CBG_03678
uniprot id: A8WVK7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 18761
gene id: 6238:CBG_18761
uniprot id: A8XU26
names: Similarity
messages: Belongs to the selenium-binding protein family.

6238:CBG 04002
gene id: 6238:CBG_04002
uniprot id: A8WVY8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

6238:CBG 20901
gene id: 6238:CBG_20901
uniprot id: A8XYW8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

6238:CBG 05880
gene id: 6238:CBG_05880
uniprot id: A8X1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 08707
gene id: 6238:CBG_08707
uniprot id: A8X775
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4 (By similarity).
messages: Synapse
messages: Ubiquitinated by rpm-1. Negatively regulated by ubiquitination by fsn-1 bound rpm-1, followed by degradation (By similarity).

6238:CBG 13260
gene id: 6238:CBG_13260
uniprot id: A8XHF2
names: Similarity
messages: Belongs to the PA28 family.

6238:CBG 17075
gene id: 6238:CBG_17075
uniprot id: A8XQF7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 21759
gene id: 6238:CBG_21759
uniprot id: A8Y0J9
names: Similarity
messages: Belongs to the peptidase M16 family.

6238:CBG 07733
gene id: 6238:CBG_07733
uniprot id: A8X473
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome
messages: phagosome
messages: trans-Golgi network membrane

6238:CBG 14136
gene id: 6238:CBG_14136
uniprot id: P32810
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

6238:CBG 15257
gene id: 6238:CBG_15257
uniprot id: A8XLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

6238:CBG 11972
gene id: 6238:CBG_11972
uniprot id: A8XEQ3
names: Similarity
messages: Belongs to the guanylate kinase family.

6238:CBG 02301
gene id: 6238:CBG_02301
uniprot id: A8WUM9
names: Similarity
messages: Belongs to the UPF0415 family.

6238:CBG 01691
gene id: 6238:CBG_01691
uniprot id: A8WR27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 18371
gene id: 6238:CBG_18371
uniprot id: A8XSJ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 09730
gene id: 6238:CBG_09730
uniprot id: G2J6N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 16136
gene id: 6238:CBG_16136
uniprot id: A8XP14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR2 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Part of a unique SNARE complex.
messages: cis-Golgi network membrane

6238:CBG 00405
gene id: 6238:CBG_00405
uniprot id: A8WN05
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

6238:CBG 04018
gene id: 6238:CBG_04018
uniprot id: A8WW00
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 12745
gene id: 6238:CBG_12745
uniprot id: A8XGH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively. In RNA Pol II, this subunit is present in 2-fold molar excess over the other subunits (By similarity).
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process (By similarity).
messages: Nucleus

6238:CBG 17402
gene id: 6238:CBG_17402
uniprot id: A8XQZ5
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 22021
gene id: 6238:CBG_22021
uniprot id: A8Y1C7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

6238:CBG 06059
gene id: 6238:CBG_06059
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 20269
gene id: 6238:CBG_20269
uniprot id: A8XXD3
names: Similarity
messages: Belongs to the thymidylate synthase family.

6238:CBG 06076
gene id: 6238:CBG_06076
uniprot id: A8X0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

6238:CBG 18957
gene id: 6238:CBG_18957
uniprot id: A8XUF7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

6238:CBG 06232
gene id: 6238:CBG_06232
uniprot id: A8X0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DDB1 family.
messages: Cytoplasm
messages: Nucleus
messages: Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair.

6238:CBG 02833
gene id: 6238:CBG_02833
uniprot id: A8WTF0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

6238:CBG 20034
gene id: 6238:CBG_20034
uniprot id: A8XWZ3
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 01612
gene id: 6238:CBG_01612
uniprot id: A8WR88
names: Similarity
messages: Belongs to the CYFIP family.

6238:CBG 01036
gene id: 6238:CBG_01036
uniprot id: A8WP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

6238:CBG 05141
gene id: 6238:CBG_05141
uniprot id: A8WZ66
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 11418
gene id: 6238:CBG_11418
uniprot id: A8XD26
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

6238:CBG 23318
gene id: 6238:CBG_23318
uniprot id: A8Y475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 00986
gene id: 6238:CBG_00986
uniprot id: A8WP61
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

6238:CBG 24150
gene id: 6238:CBG_24150
uniprot id: A8WK31
names: Similarity
messages: Belongs to the peptidase M10A family.

6238:CBG 17382
gene id: 6238:CBG_17382
uniprot id: A8XQY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15268
gene id: 6238:CBG_15268
uniprot id: A8XLI6
names: Similarity
messages: Belongs to the GCN1 family.

6238:CBG 11640
gene id: 6238:CBG_11640
uniprot id: A8XDP6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 19152
gene id: 6238:CBG_19152
uniprot id: A8XUY2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 13246
gene id: 6238:CBG_13246
uniprot id: A8XHE2
names: Similarity
messages: Belongs to the amidase family.

6238:CBG 08036
gene id: 6238:CBG_08036
uniprot id: A8X5M6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 06418
gene id: 6238:CBG_06418
uniprot id: Q04456
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Appears in mid-proliferation phase when the developing gut has four to eight cells.
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Endoplasmic reticulum lumen
messages: Expressed only in the intestine.

6238:CBG 20661
gene id: 6238:CBG_20661
uniprot id: A8XYB1
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

6238:CBG 03019
gene id: 6238:CBG_03019
uniprot id: B0K065
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 03613
gene id: 6238:CBG_03613
uniprot id: A8WVG3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 10541
gene id: 6238:CBG_10541
uniprot id: A8XBE3
names: Similarity
messages: Belongs to the filamin family.

6238:CBG 07067
gene id: 6238:CBG_07067
uniprot id: A8X3S4
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

6238:CBG 23343
gene id: 6238:CBG_23343
uniprot id: A8Y454
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 06883
gene id: 6238:CBG_06883
uniprot id: A8X3A1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

6238:CBG 06422
gene id: 6238:CBG_06422
uniprot id: A8X270
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 19620
gene id: 6238:CBG_19620
uniprot id: A8XW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

6238:CBG 19227
gene id: 6238:CBG_19227
uniprot id: A8XV47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 09085
gene id: 6238:CBG_09085
uniprot id: A8X7U3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12956
gene id: 6238:CBG_12956
uniprot id: A8XGR5
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 07654
gene id: 6238:CBG_07654
uniprot id: A8X4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane
messages: synaptic vesicle membrane

6238:CBG 14484
gene id: 6238:CBG_14484
uniprot id: Q1M2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

6238:CBG 16729
gene id: 6238:CBG_16729
uniprot id: A8XPP9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

6238:CBG 02320
gene id: 6238:CBG_02320
uniprot id: A8WUL4
names: Similarity
messages: Belongs to the phospholipase D family.

6238:CBG 14977
gene id: 6238:CBG_14977
uniprot id: A8XL49
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 19782
gene id: 6238:CBG_19782
uniprot id: A8XWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I).
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
messages: Endosome

6238:CBG 16528
gene id: 6238:CBG_16528
uniprot id: A8XPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

6238:CBG 02544
gene id: 6238:CBG_02544
uniprot id: A8WU28
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 06190
gene id: 6238:CBG_06190
uniprot id: A8X0Q0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

6238:CBG 16744
gene id: 6238:CBG_16744
uniprot id: A8XPR0
names: Similarity
messages: Belongs to the TCF/LEF family.

6238:CBG 18600
gene id: 6238:CBG_18600
uniprot id: Q60XN1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as chain editing deubiquitinating enzyme that binds and cleaves 'Lys-48'-linked polyubiquitin chains, with a preference for chains containing four or more ubiquitin molecules thereby modulating protein degradation by the ubiquitin-proteasome pathway. Probably by regulating the IGF-1-insulin-like pathway, regulates lifespan. Regulates germline DNA double-strand-break repair and apoptosis in response to DNA damage by recruiting E4 ubiquitin-protein ligase ufd-2 to DNA repair foci. Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription.
messages: Cytoplasm
messages: Forms a complex composed of deubiquitinating enzyme atx-3, adapter ubxn-5 and cdc-48.1. Forms a complex composed of deubiquitinating enzyme atx-3, E4 ubiquitin-protein ligase ufd-2 and cdc-48.1. Interacts (via RRDR motif) with cdc-48.1 (via N-terminus) and cdc-48.2 (via N-terminus); the interaction with cdc-48.1 is not required for atx-3 enzymatic activity. Interacts (via C-terminus) with ubxn-5. May interact with ned-8.
messages: Nucleus
messages: nucleolus

6238:CBG 14378
gene id: 6238:CBG_14378
uniprot id: A8XJV4
names: Similarity
messages: Belongs to the TAF11 family.

6238:CBG 02213
gene id: 6238:CBG_02213
uniprot id: A8WS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

6238:CBG 21612
gene id: 6238:CBG_21612
uniprot id: A8Y074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Chromosome
messages: Nucleus

6238:CBG 02853
gene id: 6238:CBG_02853
uniprot id: A8WTD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

6238:CBG 15526
gene id: 6238:CBG_15526
uniprot id: A8XM58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

6238:CBG 02259
gene id: 6238:CBG_02259
uniprot id: Q622B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Cytoplasm
messages: Involved in calcium binding and microtubule stabilization.

6238:CBG 18262
gene id: 6238:CBG_18262
uniprot id: A8XSA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBR family. Parkin subfamily.
messages: Forms an E3 ubiquitin ligase complex.
messages: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Mitochondrion
messages: cytosol

6238:CBG 01725
gene id: 6238:CBG_01725
uniprot id: A8WQZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

6238:CBG 17922
gene id: 6238:CBG_17922
uniprot id: A8XS42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06230
gene id: 6238:CBG_06230
uniprot id: A8X0L1
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13500
gene id: 6238:CBG_13500
uniprot id: A8XI14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Mediates both low-affinity uptake and efflux of sugar across the membrane.

6238:CBG 03957
gene id: 6238:CBG_03957
uniprot id: A8WVU7
names: Function
messages: Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Shown to have roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin (By similarity).

6238:CBG 08998
gene id: 6238:CBG_08998
uniprot id: A8X818
names: Function
names: Similarity
messages: Belongs to the ATG12 family.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

6238:CBG 11103
gene id: 6238:CBG_11103
uniprot id: A8XCE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

6238:CBG 02659
gene id: 6238:CBG_02659
uniprot id: A8WTT4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

6238:CBG 09504
gene id: 6238:CBG_09504
uniprot id: A8X8Y6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

6238:CBG 03880
gene id: 6238:CBG_03880
uniprot id: A8WWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

6238:CBG 08353
gene id: 6238:CBG_08353
uniprot id: A8X6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein srb family.
messages: Membrane

6238:CBG 01060
gene id: 6238:CBG_01060
uniprot id: A8WNZ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 16039
gene id: 6238:CBG_16039
uniprot id: A8XN84
names: Similarity
messages: Belongs to the BACURD family.

6238:CBG 12778
gene id: 6238:CBG_12778
uniprot id: A8XGJ6
names: Similarity
messages: Belongs to the calponin family.

6238:CBG 10076
gene id: 6238:CBG_10076
uniprot id: A8XAB8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

6238:CBG 01830
gene id: 6238:CBG_01830
uniprot id: A8WQQ0
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 23341
gene id: 6238:CBG_23341
uniprot id: A8Y455
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06539
gene id: 6238:CBG_06539
uniprot id: A8X2H1
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 07280
gene id: 6238:CBG_07280
uniprot id: A8X530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 09207
gene id: 6238:CBG_09207
uniprot id: A8X8C5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

6238:CBG 05695
gene id: 6238:CBG_05695
uniprot id: A8X0G8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC10 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

6238:CBG 24035
gene id: 6238:CBG_24035
uniprot id: A8WJU7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 10912
gene id: 6238:CBG_10912
uniprot id: A8XC92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway (By similarity).
messages: Belongs to the nematode receptor-like protein str family.
messages: Interacts with odr-4.
messages: cilium membrane

6238:CBG 20441
gene id: 6238:CBG_20441
uniprot id: A8XXU1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 23380
gene id: 6238:CBG_23380
uniprot id: A8Y421
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 14125
gene id: 6238:CBG_14125
uniprot id: A8XJD0
names: Function
names: Subcellular Location Annotation
messages: Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway (By similarity).
messages: Nucleus

6238:CBG 18349
gene id: 6238:CBG_18349
uniprot id: A8XSI0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

6238:CBG 05504
gene id: 6238:CBG_05504
uniprot id: A8X014
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 15725
gene id: 6238:CBG_15725
uniprot id: A8XMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

6238:CBG 19286
gene id: 6238:CBG_19286
uniprot id: A8XV95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the villin/gelsolin family.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). Binds actin but does not nucleate actin polymerization, albeit slows down elongation by blocking the barbed ends. By promoting actin depolymerization, required for the elimination of presynaptic components downstream of the egl-1, ced-4 and ced-3 apoptotic pathway during larval development.
messages: Monomer. Binds to actin monomers and filaments.
messages: cytoskeleton

6238:CBG 17474
gene id: 6238:CBG_17474
uniprot id: A8XR42
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 09777
gene id: 6238:CBG_09777
uniprot id: Q61JI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

6238:CBG 13529
gene id: 6238:CBG_13529
uniprot id: A8XI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

6238:CBG 22479
gene id: 6238:CBG_22479
uniprot id: A8Y2D7
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 21929
gene id: 6238:CBG_21929
uniprot id: A8Y172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 00650
gene id: 6238:CBG_00650
uniprot id: A8WND3
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 10499
gene id: 6238:CBG_10499
uniprot id: A8XAY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 18577
gene id: 6238:CBG_18577
uniprot id: A8XTM3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 14124
gene id: 6238:CBG_14124
uniprot id: Q619T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Binds GTP and GDP. Plays a role in uterine seam cell development.
messages: Homodimer.
messages: perinuclear region

6238:CBG 18144
gene id: 6238:CBG_18144
uniprot id: A8XT42
names: Similarity
messages: Belongs to the cyclin family.

6238:CBG 09459
gene id: 6238:CBG_09459
uniprot id: A8X922
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

6238:CBG 01057
gene id: 6238:CBG_01057
uniprot id: A8WP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

6238:CBG 05277
gene id: 6238:CBG_05277
uniprot id: A8WZI7
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 07446
gene id: 6238:CBG_07446
uniprot id: A8X4R2
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

6238:CBG 05083
gene id: 6238:CBG_05083
uniprot id: A8WZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

6238:CBG 05114
gene id: 6238:CBG_05114
uniprot id: Q61UX1
names: Function
names: Similarity
messages: Belongs to the NAC-alpha family.
messages: May promote appropriate targeting of ribosome-nascent polypeptide complexes.

6238:CBG 20070
gene id: 6238:CBG_20070
uniprot id: A8XX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 16160
gene id: 6238:CBG_16160
uniprot id: A8XNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

6238:CBG 19073
gene id: 6238:CBG_19073
uniprot id: Q60WL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

6238:CBG 07054
gene id: 6238:CBG_07054
uniprot id: A8X3T4
names: Similarity
messages: Belongs to the calponin family.

6238:CBG 09569
gene id: 6238:CBG_09569
uniprot id: A8X8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

6238:CBG 18040
gene id: 6238:CBG_18040
uniprot id: A8XSW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Mitochondrion

6238:CBG 09366
gene id: 6238:CBG_09366
uniprot id: A8X994
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

6238:CBG 05818
gene id: 6238:CBG_05818
uniprot id: A8X1K0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 03981
gene id: 6238:CBG_03981
uniprot id: P0C664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex composed of rod-1, czw-1 and zwl-1. Interacts with the spindly-like protein spdl-1. Interacts with NDC80 complex component ndc-80.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for chromosome segregation, the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores and spindle pole separation. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC80 complex to microtubules. The recruitment of spdl-1 to kinetochores relieves this inhibition. Required for embryonic development.
messages: cell cortex
messages: kinetochore
messages: spindle

6238:CBG 04048
gene id: 6238:CBG_04048
uniprot id: A8WW31
names: Similarity
messages: Belongs to the cytochrome b5 family.

6238:CBG 20772
gene id: 6238:CBG_20772
uniprot id: A8XYK7
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

6238:CBG 21823
gene id: 6238:CBG_21823
uniprot id: A8Y0W6
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 19777
gene id: 6238:CBG_19777
uniprot id: A8XWC2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

6238:CBG 21516
gene id: 6238:CBG_21516
uniprot id: A8Y0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

6238:CBG 02820
gene id: 6238:CBG_02820
uniprot id: A8WTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: FMRFamides and FMRFamide-like peptides are neuropeptides. AQTFVRF-amide inhibits the activity of dissected pharyngeal myogenic muscle system (By similarity).
messages: Secreted

6238:CBG 15223
gene id: 6238:CBG_15223
uniprot id: A8XLM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 01465
gene id: 6238:CBG_01465
uniprot id: A8WQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 16825
gene id: 6238:CBG_16825
uniprot id: C0HLB5
uniprot id: C0HLB6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Involved in necrotic cell death. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The introduction of sperm triggers V-ATPase accumulation in proximal oocytes and induces lysosomal acidification which leads to engulfing of protein aggregates by lysosomes and subsequent clearance of the aggregates. Lysosomal acidification also leads to changes in mitochondrial morphology and function. Mitochondria in distal immature oocytes are fragmented, produce high levels of reactive oxygen species (ROS) and have high membrane potential, indicative of metabolic inactivity. In contrast, mitochondria in proximal mature oocytes are tubular with lower ROS levels and membrane potential, indicative of an active metabolic state required for aggregate mobilization before clearance (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR (By similarity).
messages: Vha-11 and vha-3 are transcribed on a dicistronic transcript where vha-3 is the upstream transcript and vha-11 the downstream.

6238:CBG 03075
gene id: 6238:CBG_03075
uniprot id: A8WSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). Required for processing ITS2 sequences from rRNA intermediates during 26S rRNA maturation (By similarity). Required in the soma to promote normal proliferation and prevent germline tumor formation (By similarity).
messages: Component of the PELP1 complex, composed of at least PELP1, TEX10 and WDR18. The complex interacts with pre-60S ribosome particles.
messages: nucleolus
messages: nucleoplasm

6238:CBG 11949
gene id: 6238:CBG_11949
uniprot id: A8XEN4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 02789
gene id: 6238:CBG_02789
uniprot id: A8WTI2
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 09861
gene id: 6238:CBG_09861
uniprot id: A8X9U3
names: Similarity
messages: Belongs to the MAM33 family.

6238:CBG 19671
gene id: 6238:CBG_19671
uniprot id: Q60V75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS16 family.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. Within the HOPS complex, contributes to the normal development of gut granules in the adult intestine. The CORVET complex is proposed to function as a rab-5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for recruitment of vps-33.1 to the HOPS complex. Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with vps-33.1 but not vps-33.2.
messages: Probable core component of at least two putative endosomal tethering complexes, the homotypic fusion and vacuole protein sorting (HOPS) complex and the class C core vacuole/endosome tethering (CORVET) complex. Their common core is composed of the class C Vps proteins vps-11, vps-16 and vps-18, which in HOPS further associates with vps-33.1, vps-39 and vps-41 and in CORVET with vps-8 and vps-33.2.

6238:CBG 07618
gene id: 6238:CBG_07618
uniprot id: A8X4F7
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19349
gene id: 6238:CBG_19349
uniprot id: A8XVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

6238:CBG 16755
gene id: 6238:CBG_16755
uniprot id: Q612F5
names: Cofactor
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Consists of an N-terminal biotin carboxylation/carboxylase (BC) domain that catalyzes the transient carboxylation of the biotin covalently attached to the C-terminal biotinyl-binding/biotin carboxyl carrier (BCC) domain.
messages: Mitochondrion matrix
messages: The biotin cofactor is covalently attached to the C-terminal biotinyl-binding domain and is required for the catalytic activity.
messages: The holoenzyme is a dodecamer composed of 6 alpha subunits and 6 beta subunits. Interacts with sir-2.2.
messages: This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA (By similarity). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (By similarity).

6238:CBG 07341
gene id: 6238:CBG_07341
uniprot id: A8X4Z2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12064
gene id: 6238:CBG_12064
uniprot id: A8XEG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity).
messages: Belongs to the ARS2 family.
messages: Nucleus

6238:CBG 05843
gene id: 6238:CBG_05843
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 09481
gene id: 6238:CBG_09481
uniprot id: A8X906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
messages: Secreted

6238:CBG 16434
gene id: 6238:CBG_16434
uniprot id: A8XP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

6238:CBG 01234
gene id: 6238:CBG_01234
uniprot id: A8WPW9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09572
gene id: 6238:CBG_09572
uniprot id: A8X8S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

6238:CBG 23346
gene id: 6238:CBG_23346
uniprot id: A8Y451
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

6238:CBG 11716
gene id: 6238:CBG_11716
uniprot id: Q61FA3
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

6238:CBG 01728
gene id: 6238:CBG_01728
uniprot id: A8WQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.

6238:CBG 10571
gene id: 6238:CBG_10571
uniprot id: A8XBC2
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 15739
gene id: 6238:CBG_15739
uniprot id: A8XMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 05597
gene id: 6238:CBG_05597
uniprot id: A8X086
names: Similarity
messages: Belongs to the MAPRE family.

6238:CBG 06987
gene id: 6238:CBG_06987
uniprot id: A8X3Z4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09400
gene id: 6238:CBG_09400
uniprot id: A8X966
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 12770
gene id: 6238:CBG_12770
uniprot id: A8XGJ1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

6238:CBG 12565
gene id: 6238:CBG_12565
uniprot id: A8XG21
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22748
gene id: 6238:CBG_22748
uniprot id: A8Y331
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 04238
gene id: 6238:CBG_04238
uniprot id: A8WX07
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 13226
gene id: 6238:CBG_13226
uniprot id: A8XHC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

6238:CBG 03721
gene id: 6238:CBG_03721
uniprot id: A8WWJ6
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 04320
gene id: 6238:CBG_04320
uniprot id: A8WX87
names: Similarity
messages: Belongs to the NAC-beta family.

6238:CBG 13308
gene id: 6238:CBG_13308
uniprot id: A8XHJ3
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.

6238:CBG 20807
gene id: 6238:CBG_20807
uniprot id: A8XYN7
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

6238:CBG 20288
gene id: 6238:CBG_20288
uniprot id: A8XXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

6238:CBG 17653
gene id: 6238:CBG_17653
uniprot id: A8XRL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

6238:CBG 01751
gene id: 6238:CBG_01751
uniprot id: A8WQX6
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 20085
gene id: 6238:CBG_20085
uniprot id: A8XX22
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 16150
gene id: 6238:CBG_16150
uniprot id: A8XP04
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

6238:CBG 11944
gene id: 6238:CBG_11944
uniprot id: G2J6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 14070
gene id: 6238:CBG_14070
uniprot id: A8XJA4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 11248
gene id: 6238:CBG_11248
uniprot id: A8XDF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR (By similarity).

6238:CBG 09001
gene id: 6238:CBG_09001
uniprot id: A8X815
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

6238:CBG 17628
gene id: 6238:CBG_17628
uniprot id: A8XRN7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 15506
gene id: 6238:CBG_15506
uniprot id: A8XM67
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 18013
gene id: 6238:CBG_18013
uniprot id: A8XST9
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

6238:CBG 11102
gene id: 6238:CBG_11102
uniprot id: A8XCE8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

6238:CBG 08664
gene id: 6238:CBG_08664
uniprot id: A8X6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

6238:CBG 07528
gene id: 6238:CBG_07528
uniprot id: A8X4M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

6238:CBG 11183
gene id: 6238:CBG_11183
uniprot id: A8XCM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

6238:CBG 11139
gene id: 6238:CBG_11139
uniprot id: A8XCJ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 05673
gene id: 6238:CBG_05673
uniprot id: A8X0E8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 06820
gene id: 6238:CBG_06820
uniprot id: A8X354
names: Function
names: Similarity
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

6238:CBG 21767
gene id: 6238:CBG_21767
uniprot id: A8Y0J1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

6238:CBG 18106
gene id: 6238:CBG_18106
uniprot id: A8XT17
names: Similarity
messages: Belongs to the GILT family.

6238:CBG 09006
gene id: 6238:CBG_09006
uniprot id: A8X811
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Antagonistic role in the Wnt signaling pathway that operates in embryogenesis (By similarity). When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation (By similarity). Has a role in blastomere signaling during endoderm specification (By similarity). Component of the beta-catenin-lit-1 complex which promotes phosphorylation, down-regulation and subcellular relocation of pop-1 (By similarity). Within the complex, activates lit-1-dependent kinase activity (By similarity). Can substitute for bar-1 indicating functional redundancy (By similarity). Appears to have a role in centrosome positioning (By similarity). Involved in the development of distal tip cells (DTC) by regulating the asymmetric distribution of cye-1 and cki-1 between the daughters of Z1.a and Z4.p cells (By similarity).
messages: Interacts (independently of ARM repeat) with nhr-25 (By similarity). Component of the beta-catenin-lit-1 complex (also called the lit-1/wrm-1 complex or the wrm-1/lit-1 kinase complex) at least composed of lit-1 and wrm-1 (By similarity). Interacts (via N-terminus) with lit-1; the interaction is direct and activates lit-1 kinase activity which leads to the phosphorylation of pop-1 (By similarity). This promotes pop-1 interaction with par-5 and translocation of pop-1 from the nucleus to the cytoplasm (By similarity).
messages: Nucleus
messages: cell cortex

6238:CBG 03429
gene id: 6238:CBG_03429
uniprot id: A8WV16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 02821
gene id: 6238:CBG_02821
uniprot id: A8WTF7
names: Function
names: Similarity
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.

6238:CBG 00979
gene id: 6238:CBG_00979
uniprot id: Q626H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Interacts with mab-20.
messages: Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays. Involved in axon guidance of SDQL neurons during neurogenesis.

6238:CBG 09984
gene id: 6238:CBG_09984
uniprot id: A8XA37
names: Similarity
messages: Belongs to the lin-52 family.

6238:CBG 12957
gene id: 6238:CBG_12957
uniprot id: A8XGR6
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 03824
gene id: 6238:CBG_03824
uniprot id: A8WWU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 22279
gene id: 6238:CBG_22279
uniprot id: A8Y1Z0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 04135
gene id: 6238:CBG_04135
uniprot id: A8WVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

6238:CBG 18317
gene id: 6238:CBG_18317
uniprot id: A8XSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

6238:CBG 19807
gene id: 6238:CBG_19807
uniprot id: A8XW95
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 13239
gene id: 6238:CBG_13239
uniprot id: A8XHD6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 24740
gene id: 6238:CBG_24740
uniprot id: A8WLD3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

6238:CBG 08080
gene id: 6238:CBG_08080
uniprot id: A8X5R5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

6238:CBG 04265
gene id: 6238:CBG_04265
uniprot id: A8WX33
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 08837
gene id: 6238:CBG_08837
uniprot id: A8X7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

6238:CBG 05531
gene id: 6238:CBG_05531
uniprot id: A8X034
names: Similarity
messages: Belongs to the phospholipase D family.

6238:CBG 13442
gene id: 6238:CBG_13442
uniprot id: A8XHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

6238:CBG 19011
gene id: 6238:CBG_19011
uniprot id: A8XUK2
names: Similarity
messages: Belongs to the TGF-beta family.

6238:CBG 08326
gene id: 6238:CBG_08326
uniprot id: A8X6B1
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

6238:CBG 19017
gene id: 6238:CBG_19017
uniprot id: A8XUK7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 04990
gene id: 6238:CBG_04990
uniprot id: A8WYX9
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 21723
gene id: 6238:CBG_21723
uniprot id: A8Y0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

6238:CBG 07736
gene id: 6238:CBG_07736
uniprot id: A8X470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane

6238:CBG 21837
gene id: 6238:CBG_21837
uniprot id: A8Y0W6
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 06744
gene id: 6238:CBG_06744
uniprot id: A8X2Z9
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 05668
gene id: 6238:CBG_05668
uniprot id: A8X0E3
names: Similarity
messages: Belongs to the GSKIP family.

6238:CBG 07414
gene id: 6238:CBG_07414
uniprot id: A8X4T9
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 07571
gene id: 6238:CBG_07571
uniprot id: A8X4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

6238:CBG 04491
gene id: 6238:CBG_04491
uniprot id: A8WXR8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

6238:CBG 14540
gene id: 6238:CBG_14540
uniprot id: A8XK55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

6238:CBG 03985
gene id: 6238:CBG_03985
uniprot id: Q61XH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Cytoplasm
messages: Nucleus
messages: Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress.

6238:CBG 09545
gene id: 6238:CBG_09545
uniprot id: P0C659
names: Similarity
messages: Belongs to the EIF1AD family.

6238:CBG 10808
gene id: 6238:CBG_10808
uniprot id: A8XBU5
names: Similarity
messages: Belongs to the FMO family.

6238:CBG 22943
gene id: 6238:CBG_22943
uniprot id: A8Y3L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

6238:CBG 14606
gene id: 6238:CBG_14606
uniprot id: A8XKA1
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

6238:CBG 04258
gene id: 6238:CBG_04258
uniprot id: A8WX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

6238:CBG 23177
gene id: 6238:CBG_23177
uniprot id: A8Y4I6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 08757
gene id: 6238:CBG_08757
uniprot id: A8X7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Membrane

6238:CBG 10454
gene id: 6238:CBG_10454
uniprot id: A8XB93
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

6238:CBG 13421
gene id: 6238:CBG_13421
uniprot id: A8XHT2
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

6238:CBG 11861
gene id: 6238:CBG_11861
uniprot id: A8XE62
names: Similarity
messages: Belongs to the dynein heavy chain family.

6238:CBG 00747
gene id: 6238:CBG_00747
uniprot id: A8WN56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Cystine/H(+) symporter that mediates export of cystine, the oxidized dimer of cysteine, from lysosomes (By similarity). May play a role in the degradation of engulfed apoptotic cells (By similarity).
messages: Lysosome membrane
messages: phagosome

6238:CBG 16503
gene id: 6238:CBG_16503
uniprot id: A8XPD0
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

6238:CBG 19228
gene id: 6238:CBG_19228
uniprot id: A8XV48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

6238:CBG 19844
gene id: 6238:CBG_19844
uniprot id: E3CU74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

6238:CBG 13773
gene id: 6238:CBG_13773
uniprot id: A8XIN7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

6238:CBG 18638
gene id: 6238:CBG_18638
uniprot id: A8XTS4
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 07064
gene id: 6238:CBG_07064
uniprot id: A8X3S7
names: Subcellular Location Annotation
messages: nucleolus

6238:CBG 06069
gene id: 6238:CBG_06069
uniprot id: A8X0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

6238:CBG 03264
gene id: 6238:CBG_03264
uniprot id: A8WSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

6238:CBG 04942
gene id: 6238:CBG_04942
uniprot id: A8WYV1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 07641
gene id: 6238:CBG_07641
uniprot id: A8X4D9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22776
gene id: 6238:CBG_22776
uniprot id: A8Y2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 24344
gene id: 6238:CBG_24344
uniprot id: A8WKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

6238:CBG 02231
gene id: 6238:CBG_02231
uniprot id: A8WS81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 12650
gene id: 6238:CBG_12650
uniprot id: A8XG92
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 00883
gene id: 6238:CBG_00883
uniprot id: A8WPE5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 00981
gene id: 6238:CBG_00981
uniprot id: A8WP66
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes (By similarity).

6238:CBG 01117
gene id: 6238:CBG_01117
uniprot id: A8WPL4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09697
gene id: 6238:CBG_09697
uniprot id: A8X8G9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03991
gene id: 6238:CBG_03991
uniprot id: A8WVX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

6238:CBG 10781
gene id: 6238:CBG_10781
uniprot id: A8XBS6
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.

6238:CBG 05842
gene id: 6238:CBG_05842
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 13900
gene id: 6238:CBG_13900
uniprot id: A8XJ30
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

6238:CBG 19281
gene id: 6238:CBG_19281
uniprot id: A8XV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 23475
gene id: 6238:CBG_23475
uniprot id: A8Y3U1
names: Similarity
messages: Belongs to the mitoguardin family.

6238:CBG 11706
gene id: 6238:CBG_11706
uniprot id: A8XDX2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c (By similarity).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element (By similarity).
messages: Mitochondrion membrane
messages: Trimethylated by ATPSCKMT at Lys-84. Methylation may be required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration.

6238:CBG 04528
gene id: 6238:CBG_04528
uniprot id: A8WXN8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20761
gene id: 6238:CBG_20761
uniprot id: A8XYJ8
names: Similarity
messages: Belongs to the WASH1 family.

6238:CBG 18993
gene id: 6238:CBG_18993
uniprot id: A8XUI8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 13304
gene id: 6238:CBG_13304
uniprot id: A8XHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

6238:CBG 16759
gene id: 6238:CBG_16759
uniprot id: A8XPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

6238:CBG 22771
gene id: 6238:CBG_22771
uniprot id: A8Y2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 04929
gene id: 6238:CBG_04929
uniprot id: A8WYU0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 07448
gene id: 6238:CBG_07448
uniprot id: A8X4R0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 03696
gene id: 6238:CBG_03696
uniprot id: A8WVM1
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 08224
gene id: 6238:CBG_08224
uniprot id: A8X633
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenomatous polyposis coli (APC) family.
messages: Cytoplasm
messages: Has a role in endoderm cell specification and pharyngeal development. Required for the migration of epithelial cells, organization of the anterior seam cells and ceh-13 expression during embryo morphogenesis. Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation. During larval development, apr-1 is required for expression of lin-39 in P3-8.p. Shown to negatively regulate Wnt signaling in vulval precursor cells. Has a role in cell division by establishing the polarity of the mother cell which forms the asymmetries of the daughter nuclei. Thought to regulate export of wrm-1 from the nucleus possibly as part of a complex involving pry-1.
messages: Interacts (via N-terminus) with bar-1 and hmp-2; the interaction with hmp-2 is relatively weak. Interacts (via C-terminus) with pry-1 (via N-terminus). Probably associates with bar-1, gsk-3, pry-1 in a complex (By similarity).
messages: Nucleus
messages: adherens junction

6238:CBG 01321
gene id: 6238:CBG_01321
uniprot id: A8WQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 11571
gene id: 6238:CBG_11571
uniprot id: A8XDI7
names: Similarity
messages: Belongs to the AHA1 family.

6238:CBG 04949
gene id: 6238:CBG_04949
uniprot id: A8WYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 13757
gene id: 6238:CBG_13757
uniprot id: A8XIM3
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 15124
gene id: 6238:CBG_15124
uniprot id: A8XLF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 12902
gene id: 6238:CBG_12902
uniprot id: A8XGM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 11663
gene id: 6238:CBG_11663
uniprot id: A8XDR5
names: Developmental Stage
names: Disruption Phenotype
names: Function
messages: Expressed from early larval stages through to adulthood.
messages: Sex-determining factor which regulates hermaphrodite development.
messages: Temperature-sensitive phenotype in which XX animals are self-sterile, do not produce spermatocytes, but ovulate and produce progeny when mated with males; XO animals develop as males, but some switch to oogenesis in later life. Animals do not produce fog-3 proteins responsible for controlling germ cell fate. RNAi-mediated knock-down results in 95% female progeny.

6238:CBG 05830
gene id: 6238:CBG_05830
uniprot id: A8X1J1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 18107
gene id: 6238:CBG_18107
uniprot id: A8XT18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

6238:CBG 22211
gene id: 6238:CBG_22211
uniprot id: Q4VT45
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

6238:CBG 22843
gene id: 6238:CBG_22843
uniprot id: A8Y367
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 12314
gene id: 6238:CBG_12314
uniprot id: A8XFJ3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

6238:CBG 05961
gene id: 6238:CBG_05961
uniprot id: A8X183
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

6238:CBG 05898
gene id: 6238:CBG_05898
uniprot id: A8X1D8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 16919
gene id: 6238:CBG_16919
uniprot id: A8XQ20
names: Similarity
messages: Belongs to the CD36 family.

6238:CBG 21048
gene id: 6238:CBG_21048
uniprot id: A8XZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Mitochondrion
messages: Thought to be a regulatory component of the ATP-synthesizing complex in the mitochondria.

6238:CBG 09807
gene id: 6238:CBG_09807
uniprot id: A8X9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pym family.
messages: Cytoplasm

6238:CBG 11771
gene id: 6238:CBG_11771
uniprot id: A8XE05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

6238:CBG 01720
gene id: 6238:CBG_01720
uniprot id: A8WR03
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 18327
gene id: 6238:CBG_18327
uniprot id: A8XSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

6238:CBG 17874
gene id: 6238:CBG_17874
uniprot id: A8XRZ8
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

6238:CBG 24582
gene id: 6238:CBG_24582
uniprot id: A8WL10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

6238:CBG 11742
gene id: 6238:CBG_11742
uniprot id: A8XDU2
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

6238:CBG 01499
gene id: 6238:CBG_01499
uniprot id: G2J6C6
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 21247
gene id: 6238:CBG_21247
uniprot id: A8XZI6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

6238:CBG 16080
gene id: 6238:CBG_16080
uniprot id: A8XN54
names: Similarity
messages: Belongs to the glutathione peroxidase family.

6238:CBG 11531
gene id: 6238:CBG_11531
uniprot id: A8XCS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCB family.
messages: Cytoplasm

6238:CBG 06114
gene id: 6238:CBG_06114
uniprot id: A8X0V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

6238:CBG 03599
gene id: 6238:CBG_03599
uniprot id: A8WVF3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

6238:CBG 10264
gene id: 6238:CBG_10264
uniprot id: A8XAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 13827
gene id: 6238:CBG_13827
uniprot id: A8XIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

6238:CBG 02500
gene id: 6238:CBG_02500
uniprot id: A8WU64
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

6238:CBG 03801
gene id: 6238:CBG_03801
uniprot id: A8WWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 10799
gene id: 6238:CBG_10799
uniprot id: A8XBT9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 14798
gene id: 6238:CBG_14798
uniprot id: G2J6V0
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 02554
gene id: 6238:CBG_02554
uniprot id: A8WU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 03422
gene id: 6238:CBG_03422
uniprot id: A8WV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: extracellular matrix

6238:CBG 23103
gene id: 6238:CBG_23103
uniprot id: A8Y4P7
names: Similarity
messages: Belongs to the complex I LYR family.

6238:CBG 13470
gene id: 6238:CBG_13470
uniprot id: Q17295
names: Function
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Accumulation defines the body wall muscle cell fate during embryogenesis.
messages: Body wall muscle cells; in clonal muscle precursors, in a set of early embryonic blastomeres (the ms-granddaughters), and in six glial-like cells called GLRS.
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

6238:CBG 01785
gene id: 6238:CBG_01785
uniprot id: A8WQU3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

6238:CBG 16621
gene id: 6238:CBG_16621
uniprot id: A8XPL8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 22765
gene id: 6238:CBG_22765
uniprot id: A8Y2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

6238:CBG 07376
gene id: 6238:CBG_07376
uniprot id: A8X4W8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

6238:CBG 19040
gene id: 6238:CBG_19040
uniprot id: A8XUM7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

6238:CBG 05755
gene id: 6238:CBG_05755
uniprot id: A8X1Q1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 07591
gene id: 6238:CBG_07591
uniprot id: A8X4H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

6238:CBG 17901
gene id: 6238:CBG_17901
uniprot id: A8XS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 00029
gene id: 6238:CBG_00029
uniprot id: Q9GZ03
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09994
gene id: 6238:CBG_09994
uniprot id: Q61J08
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the mcm2-7 complex. The complex forms a toroidal hexameric ring with the proposed subunit order mcm2-mcm6-mcm4-mcm7-mcm3-mcm5 (By simililarity).
messages: Early fractionation of eukaryotic MCM proteins yielded a variety of dimeric, trimeric and tetrameric complexes with unclear biological significance. Specifically a MCM467 subcomplex is shown to have in vitro helicase activity which is inhibited by the MCM2 subunit. The MCM2-7 hexamer is the proposed physiological active complex.
messages: Nucleus

6238:CBG 01801
gene id: 6238:CBG_01801
uniprot id: A8WQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 02160
gene id: 6238:CBG_02160
uniprot id: A8WS31
names: Similarity
messages: Belongs to the actin family.

6238:CBG 18072
gene id: 6238:CBG_18072
uniprot id: A8XSZ0
names: Similarity
messages: Belongs to the GPATCH1 family.

6238:CBG 09138
gene id: 6238:CBG_09138
uniprot id: A8X861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

6238:CBG 09029
gene id: 6238:CBG_09029
uniprot id: A8X7Z5
names: Subcellular Location Annotation
messages: adherens junction

6238:CBG 05414
gene id: 6238:CBG_05414
uniprot id: A8WZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

6238:CBG 10857
gene id: 6238:CBG_10857
uniprot id: A8XC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 06829
gene id: 6238:CBG_06829
uniprot id: A8X360
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 18010
gene id: 6238:CBG_18010
uniprot id: A8XST6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

6238:CBG 00973
gene id: 6238:CBG_00973
uniprot id: Q626I0
names: Domain
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.
messages: The molybdenum cofactor biosynthesis protein-like region may not be functional.

6238:CBG 24607
gene id: 6238:CBG_24607
uniprot id: P41955
names: Cofactor
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), iron-sulfur protein (IP), and a cytochrome b560 composed of two transmembrane proteins.
messages: Is expressed at a constant level throughout development.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Mediates resistance to enteropathogenic E.coli infection (By similarity).
messages: Mitochondrion inner membrane
messages: The heme is bound between the two transmembrane subunits.

6238:CBG 13066
gene id: 6238:CBG_13066
uniprot id: A8XH01
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

6238:CBG 05465
gene id: 6238:CBG_05465
uniprot id: A8WZY0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 01712
gene id: 6238:CBG_01712
uniprot id: A8WR08
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 02495
gene id: 6238:CBG_02495
uniprot id: A8WU67
names: Similarity
messages: Belongs to the intermediate filament family.

6238:CBG 14945
gene id: 6238:CBG_14945
uniprot id: A8XL25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of crn-1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

6238:CBG 18398
gene id: 6238:CBG_18398
uniprot id: A8XSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

6238:CBG 13485
gene id: 6238:CBG_13485
uniprot id: A8XHM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

6238:CBG 02656
gene id: 6238:CBG_02656
uniprot id: A8WTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 16677
gene id: 6238:CBG_16677
uniprot id: A8XPA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

6238:CBG 06439
gene id: 6238:CBG_06439
uniprot id: A8X282
names: Similarity
messages: Belongs to the TFIIB family.

6238:CBG 12586
gene id: 6238:CBG_12586
uniprot id: A8XG39
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 21146
gene id: 6238:CBG_21146
uniprot id: A8XZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein srb family.
messages: Membrane

6238:CBG 09465
gene id: 6238:CBG_09465
uniprot id: A8X916
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

6238:CBG 01578
gene id: 6238:CBG_01578
uniprot id: A8WRB9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 03669
gene id: 6238:CBG_03669
uniprot id: A8WVK0
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

6238:CBG 06118
gene id: 6238:CBG_06118
uniprot id: A8X0V2
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

6238:CBG 01241
gene id: 6238:CBG_01241
uniprot id: A8WPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 01115
gene id: 6238:CBG_01115
uniprot id: A8WPL2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10452
gene id: 6238:CBG_10452
uniprot id: A8XB91
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

6238:CBG 19562
gene id: 6238:CBG_19562
uniprot id: A8XVW7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09065
gene id: 6238:CBG_09065
uniprot id: A8X7W0
names: Similarity
messages: Belongs to the canopy family.

6238:CBG 21627
gene id: 6238:CBG_21627
uniprot id: A8Y087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Chromosome
messages: Nucleus

6238:CBG 02966
gene id: 6238:CBG_02966
uniprot id: A8WT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

6238:CBG 03415
gene id: 6238:CBG_03415
uniprot id: A8WV03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

6238:CBG 03866
gene id: 6238:CBG_03866
uniprot id: A8WWY3
names: Similarity
messages: Belongs to the BLM10 family.

6238:CBG 13078
gene id: 6238:CBG_13078
uniprot id: A8XH13
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 09167
gene id: 6238:CBG_09167
uniprot id: Q9GZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

6238:CBG 16323
gene id: 6238:CBG_16323
uniprot id: A8XNP3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 02577
gene id: 6238:CBG_02577
uniprot id: A8WU02
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

6238:CBG 11296
gene id: 6238:CBG_11296
uniprot id: A8XDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

6238:CBG 18391
gene id: 6238:CBG_18391
uniprot id: A8XSL5
names: Similarity
messages: Belongs to the AAA ATPase family.

6238:CBG 03148
gene id: 6238:CBG_03148
uniprot id: A8WSP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

6238:CBG 02923
gene id: 6238:CBG_02923
uniprot id: A8WT76
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 00593
gene id: 6238:CBG_00593
uniprot id: A8WNI1
names: Similarity
messages: Belongs to the TIP family.

6238:CBG 20410
gene id: 6238:CBG_20410
uniprot id: A8XXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

6238:CBG 08329
gene id: 6238:CBG_08329
uniprot id: A8X6B4
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 03614
gene id: 6238:CBG_03614
uniprot id: A8WVG4
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

6238:CBG 09642
gene id: 6238:CBG_09642
uniprot id: A8X8K8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

6238:CBG 03915
gene id: 6238:CBG_03915
uniprot id: A8WVR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

6238:CBG 18137
gene id: 6238:CBG_18137
uniprot id: A8XT37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

6238:CBG 23457
gene id: 6238:CBG_23457
uniprot id: A8Y3V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tom20 family.
messages: Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity).
messages: Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex).
messages: Mitochondrion outer membrane

6238:CBG 02463
gene id: 6238:CBG_02463
uniprot id: A8WU97
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13719
gene id: 6238:CBG_13719
uniprot id: A8XIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

6238:CBG 03860
gene id: 6238:CBG_03860
uniprot id: A8WWX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 04611
gene id: 6238:CBG_04611
uniprot id: A8WY21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

6238:CBG 13668
gene id: 6238:CBG_13668
uniprot id: A8XIF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 20699
gene id: 6238:CBG_20699
uniprot id: A8XYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 08696
gene id: 6238:CBG_08696
uniprot id: A8X6S7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 07560
gene id: 6238:CBG_07560
uniprot id: A8X4K1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

6238:CBG 02987
gene id: 6238:CBG_02987
uniprot id: A8WT18
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 05472
gene id: 6238:CBG_05472
uniprot id: A8WZY7
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

6238:CBG 16082
gene id: 6238:CBG_16082
uniprot id: A8XN52
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03136
gene id: 6238:CBG_03136
uniprot id: A8WSQ2
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

6238:CBG 05815
gene id: 6238:CBG_05815
uniprot id: A8X1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 03225
gene id: 6238:CBG_03225
uniprot id: Q61Z83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tom40 family.
messages: Channel-forming protein essential for import of protein precursors into mitochondria. Specifically required for nnt-1 accumulation in the mitochondria and may be involved in the secretion of daf-28/insulin from the mitochondria. Required for embryonic and larval development.
messages: Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Interacts with mitochondrial targeting sequences.
messages: Mitochondrion outer membrane

6238:CBG 13447
gene id: 6238:CBG_13447
uniprot id: A8XHR0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 00344
gene id: 6238:CBG_00344
uniprot id: A8WMV6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

6238:CBG 03199
gene id: 6238:CBG_03199
uniprot id: A8WSK3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

6238:CBG 09985
gene id: 6238:CBG_09985
uniprot id: A8XA38
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

6238:CBG 13345
gene id: 6238:CBG_13345
uniprot id: A8XHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 14929
gene id: 6238:CBG_14929
uniprot id: A8XL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 01236
gene id: 6238:CBG_01236
uniprot id: A8WPX1
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 03980
gene id: 6238:CBG_03980
uniprot id: A8WVW6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

6238:CBG 16408
gene id: 6238:CBG_16408
uniprot id: A8XNI2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

6238:CBG 01820
gene id: 6238:CBG_01820
uniprot id: A8WQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

6238:CBG 13541
gene id: 6238:CBG_13541
uniprot id: Q61B10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particle containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
messages: nucleolus

6238:CBG 21264
gene id: 6238:CBG_21264
uniprot id: A8XZQ4
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 06263
gene id: 6238:CBG_06263
uniprot id: A8X0I2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

6238:CBG 18887
gene id: 6238:CBG_18887
uniprot id: A8XUA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

6238:CBG 06194
gene id: 6238:CBG_06194
uniprot id: A8X0P6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

6238:CBG 23796
gene id: 6238:CBG_23796
uniprot id: A8WJB2
names: Similarity
messages: Belongs to the WD repeat coronin family.

6238:CBG 14230
gene id: 6238:CBG_14230
uniprot id: A8XJK0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 03465
gene id: 6238:CBG_03465
uniprot id: A8WV48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

6238:CBG 21817
gene id: 6238:CBG_21817
uniprot id: A8Y0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

6238:CBG 06644
gene id: 6238:CBG_06644
uniprot id: A8X2R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZFPL1 family.
messages: Membrane

6238:CBG 23201
gene id: 6238:CBG_23201
uniprot id: A8Y4G9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 00076
gene id: 6238:CBG_00076
uniprot id: A8WM92
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

6238:CBG 15914
gene id: 6238:CBG_15914
uniprot id: A8XN24
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 11004
gene id: 6238:CBG_11004
uniprot id: A8XC08
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 14465
gene id: 6238:CBG_14465
uniprot id: A8XK02
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

6238:CBG 10442
gene id: 6238:CBG_10442
uniprot id: E3CU18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 01816
gene id: 6238:CBG_01816
uniprot id: A8WQR3
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06986
gene id: 6238:CBG_06986
uniprot id: A8X3Z5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13388
gene id: 6238:CBG_13388
uniprot id: A8XHV8
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 08749
gene id: 6238:CBG_08749
uniprot id: A8X7A9
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

6238:CBG 15231
gene id: 6238:CBG_15231
uniprot id: A8XLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

6238:CBG 18187
gene id: 6238:CBG_18187
uniprot id: A8XT79
names: Similarity
messages: Belongs to the GET4 family.

6238:CBG 16979
gene id: 6238:CBG_16979
uniprot id: A8XQ67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 02799
gene id: 6238:CBG_02799
uniprot id: A8WTH5
names: Similarity
messages: Belongs to the UPF0729 family.

6238:CBG 09646
gene id: 6238:CBG_09646
uniprot id: A8X8K4
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

6238:CBG 05683
gene id: 6238:CBG_05683
uniprot id: A8X0F7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 09575
gene id: 6238:CBG_09575
uniprot id: A8X8S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 01370
gene id: 6238:CBG_01370
uniprot id: A8WQ91
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

6238:CBG 02567
gene id: 6238:CBG_02567
uniprot id: A8WU12
names: Similarity
messages: Belongs to the SNF7 family.

6238:CBG 00735
gene id: 6238:CBG_00735
uniprot id: A8WN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Belongs to the sideroflexin family.
messages: Membrane

6238:CBG 00364
gene id: 6238:CBG_00364
uniprot id: A8WMX1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02555
gene id: 6238:CBG_02555
uniprot id: A8WU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 15225
gene id: 6238:CBG_15225
uniprot id: A8XLM3
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 23897
gene id: 6238:CBG_23897
uniprot id: A8WJJ2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

6238:CBG 04950
gene id: 6238:CBG_04950
uniprot id: A8WYV6
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12356
gene id: 6238:CBG_12356
uniprot id: A8XF85
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

6238:CBG 04922
gene id: 6238:CBG_04922
uniprot id: A8WYT3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 10000
gene id: 6238:CBG_10000
uniprot id: C0HLB5
uniprot id: C0HLB6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Involved in necrotic cell death. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The introduction of sperm triggers V-ATPase accumulation in proximal oocytes and induces lysosomal acidification which leads to engulfing of protein aggregates by lysosomes and subsequent clearance of the aggregates. Lysosomal acidification also leads to changes in mitochondrial morphology and function. Mitochondria in distal immature oocytes are fragmented, produce high levels of reactive oxygen species (ROS) and have high membrane potential, indicative of metabolic inactivity. In contrast, mitochondria in proximal mature oocytes are tubular with lower ROS levels and membrane potential, indicative of an active metabolic state required for aggregate mobilization before clearance (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR (By similarity).
messages: Vha-11 and vha-3 are transcribed on a dicistronic transcript where vha-3 is the upstream transcript and vha-11 the downstream.

6238:CBG 03789
gene id: 6238:CBG_03789
uniprot id: A8WWQ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

6238:CBG 18455
gene id: 6238:CBG_18455
uniprot id: A8XTC7
names: Similarity
messages: Belongs to the FGGY kinase family.

6238:CBG 13240
gene id: 6238:CBG_13240
uniprot id: A8XHD7
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 20268
gene id: 6238:CBG_20268
uniprot id: A8XXD4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

6238:CBG 10214
gene id: 6238:CBG_10214
uniprot id: A8XAU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

6238:CBG 20205
gene id: 6238:CBG_20205
uniprot id: A8XX72
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

6238:CBG 14871
gene id: 6238:CBG_14871
uniprot id: A8XKV9
names: Similarity
messages: Belongs to the TCF25 family.

6238:CBG 13606
gene id: 6238:CBG_13606
uniprot id: A8XIA6
names: Similarity
messages: Belongs to the peptidase C19 family.

6238:CBG 21174
gene id: 6238:CBG_21174
uniprot id: A8XZB8
names: Subcellular Location Annotation
messages: nucleolus

6238:CBG 06350
gene id: 6238:CBG_06350
uniprot id: A8X213
names: Similarity
messages: Belongs to the AP-2 family.

6238:CBG 04560
gene id: 6238:CBG_04560
uniprot id: Q61W58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Homodimer. Interacts (via TPR repeat-binding and central region) with pph-5 (via phosphatase domain); the interaction promotes pph-5 phosphatase activity. Interacts (via central region) with co-chaperone cdc-37 (via N-terminus); the interaction inhibits daf-21 ATPase activity.
messages: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another signal transduction component that regulates cGMP levels, plays a role in dauer formation and chemotaxis to non-volatile and volatile attractants detected by AWC sensory neurons. Participates in the control of cell cycle progression at the prophase/metaphase transition in oocyte development by ensuring the activity of wee-1.3 kinase, which negatively regulates cdk-1 through its phosphorylation. Regulates yap-1 nuclear export after heat shock treatment.
messages: The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
messages: perinuclear region

6238:CBG 21524
gene id: 6238:CBG_21524
uniprot id: A8Y0B3
names: Similarity
messages: Belongs to the KTI12 family.

6238:CBG 03460
gene id: 6238:CBG_03460
uniprot id: A8WV43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

6238:CBG 07646
gene id: 6238:CBG_07646
uniprot id: A8X4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane

6238:CBG 07861
gene id: 6238:CBG_07861
uniprot id: A8X5A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 11423
gene id: 6238:CBG_11423
uniprot id: A8XD21
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 22669
gene id: 6238:CBG_22669
uniprot id: A8Y2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 03049
gene id: 6238:CBG_03049
uniprot id: A8WSX0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17284
gene id: 6238:CBG_17284
uniprot id: A8XQR7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

6238:CBG 23256
gene id: 6238:CBG_23256
uniprot id: A8Y4C5
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

6238:CBG 06436
gene id: 6238:CBG_06436
uniprot id: A8X280
names: Similarity
messages: Belongs to the CFAP36 family.

6238:CBG 18296
gene id: 6238:CBG_18296
uniprot id: A8XSD1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

6238:CBG 00209
gene id: 6238:CBG_00209
uniprot id: A8WMH2
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 12555
gene id: 6238:CBG_12555
uniprot id: A8XG12
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 11007
gene id: 6238:CBG_11007
uniprot id: A8XC11
names: Similarity
messages: Belongs to the FAM122 family.

6238:CBG 13890
gene id: 6238:CBG_13890
uniprot id: A8XJ39
names: Similarity
messages: Belongs to the hexokinase family.

6238:CBG 23222
gene id: 6238:CBG_23222
uniprot id: A8Y4F3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 23076
gene id: 6238:CBG_23076
uniprot id: A8Y4R8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

6238:CBG 02769
gene id: 6238:CBG_02769
uniprot id: A8WTJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG.
messages: Mitochondrion

6238:CBG 01005
gene id: 6238:CBG_01005
uniprot id: A8WP46
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

6238:CBG 18269
gene id: 6238:CBG_18269
uniprot id: A8XSA7
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 20882
gene id: 6238:CBG_20882
uniprot id: A8XYV4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 11518
gene id: 6238:CBG_11518
uniprot id: A8XCT2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

6238:CBG 08048
gene id: 6238:CBG_08048
uniprot id: A8X5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

6238:CBG 13013
gene id: 6238:CBG_13013
uniprot id: A8XGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

6238:CBG 02453
gene id: 6238:CBG_02453
uniprot id: A8WUA5
names: Similarity
messages: Belongs to the TPA1 family.

6238:CBG 11281
gene id: 6238:CBG_11281
uniprot id: A8XDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane

6238:CBG 19685
gene id: 6238:CBG_19685
uniprot id: A8XW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

6238:CBG 06670
gene id: 6238:CBG_06670
uniprot id: Q61RA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. Required for checkpoint mediated cell cycle arrest in response to DNA damage in germline cells. Essential for embryogenesis (By similarity).

6238:CBG 11493
gene id: 6238:CBG_11493
uniprot id: A8XCV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 09321
gene id: 6238:CBG_09321
uniprot id: A8X9D4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10417
gene id: 6238:CBG_10417
uniprot id: A8XB58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 10064
gene id: 6238:CBG_10064
uniprot id: A8XAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Mitochondrion

6238:CBG 05177
gene id: 6238:CBG_05177
uniprot id: A8WZB2
names: Similarity
messages: Belongs to the SAPAP family.

6238:CBG 21547
gene id: 6238:CBG_21547
uniprot id: A8Y0C8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 04319
gene id: 6238:CBG_04319
uniprot id: A8WX86
names: Similarity
messages: Belongs to the SNF7 family.

6238:CBG 06061
gene id: 6238:CBG_06061
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 10424
gene id: 6238:CBG_10424
uniprot id: A8XB65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 07642
gene id: 6238:CBG_07642
uniprot id: A8X4D8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 13737
gene id: 6238:CBG_13737
uniprot id: A8XIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

6238:CBG 12659
gene id: 6238:CBG_12659
uniprot id: A8XGA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

6238:CBG 19324
gene id: 6238:CBG_19324
uniprot id: A8XVC9
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 01240
gene id: 6238:CBG_01240
uniprot id: A8WPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 11156
gene id: 6238:CBG_11156
uniprot id: A8XCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

6238:CBG 21997
gene id: 6238:CBG_21997
uniprot id: G2J721
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 08963
gene id: 6238:CBG_08963
uniprot id: A8X847
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

6238:CBG 18026
gene id: 6238:CBG_18026
uniprot id: A8XSV0
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

6238:CBG 06465
gene id: 6238:CBG_06465
uniprot id: A8X2A2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 08000
gene id: 6238:CBG_08000
uniprot id: A8X5J7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipid scramblase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 11995
gene id: 6238:CBG_11995
uniprot id: A8XEA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 10567
gene id: 6238:CBG_10567
uniprot id: A8XBC5
names: Similarity
messages: Belongs to the ATG101 family.

6238:CBG 02462
gene id: 6238:CBG_02462
uniprot id: Q621J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Although it is unknown whether it is a serine/threonine or a tyrosine protein kinase, it is strongly related to serine/threonine-protein kinase family.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Protein kinase that plays a central role in centrosome duplication. Paternal copy is required to regulate synthesis of daughter centrioles prior to fertilization. Maternal copy regulates centrosome duplication during later cell cycles. Functions upstream of sas-5 and sas-6, and is required for their localization to the centrosome (By similarity).
messages: centriole

6238:CBG 06892
gene id: 6238:CBG_06892
uniprot id: A8X3A8
names: Similarity
messages: Belongs to the peroxin-19 family.

6238:CBG 23501
gene id: 6238:CBG_23501
uniprot id: A8Y3R9
names: Similarity
messages: Belongs to the PPP1R37 family.

6238:CBG 12230
gene id: 6238:CBG_12230
uniprot id: A8XEX9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 03181
gene id: 6238:CBG_03181
uniprot id: A8WSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

6238:CBG 02732
gene id: 6238:CBG_02732
uniprot id: A8WTM4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

6238:CBG 16161
gene id: 6238:CBG_16161
uniprot id: A8XNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 18573
gene id: 6238:CBG_18573
uniprot id: A8XTM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 03302
gene id: 6238:CBG_03302
uniprot id: A8WSC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

6238:CBG 18237
gene id: 6238:CBG_18237
uniprot id: A8XS78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 20877
gene id: 6238:CBG_20877
uniprot id: A8XYV0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 03984
gene id: 6238:CBG_03984
uniprot id: A8WVX0
names: Similarity
messages: Belongs to the SNF7 family.

6238:CBG 01066
gene id: 6238:CBG_01066
uniprot id: A8WNZ3
names: Similarity
messages: Belongs to the CWC16 family.

6238:CBG 07987
gene id: 6238:CBG_07987
uniprot id: A8X5I4
names: Similarity
messages: Belongs to the LSM14 family.

6238:CBG 21213
gene id: 6238:CBG_21213
uniprot id: A8XZK9
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03758
gene id: 6238:CBG_03758
uniprot id: A8WWN0
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 04136
gene id: 6238:CBG_04136
uniprot id: A8WVN0
names: Similarity
messages: Belongs to the sorting nexin family.

6238:CBG 25151
gene id: 6238:CBG_25151
uniprot id: B0K086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

6238:CBG 17273
gene id: 6238:CBG_17273
uniprot id: A8XQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

6238:CBG 03002
gene id: 6238:CBG_03002
uniprot id: A8WT09
names: Similarity
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.

6238:CBG 12546
gene id: 6238:CBG_12546
uniprot id: A8XG05
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 01815
gene id: 6238:CBG_01815
uniprot id: A8WQR4
names: Caution
names: Cofactor
names: Function
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Metalloprotease.

6238:CBG 00427
gene id: 6238:CBG_00427
uniprot id: A8WN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

6238:CBG 08992
gene id: 6238:CBG_08992
uniprot id: Q61LC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Golgi apparatus membrane
messages: Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi (By similarity).

6238:CBG 06842
gene id: 6238:CBG_06842
uniprot id: A8X371
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

6238:CBG 03407
gene id: 6238:CBG_03407
uniprot id: A8WUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 04316
gene id: 6238:CBG_04316
uniprot id: A8WX82
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 04633
gene id: 6238:CBG_04633
uniprot id: A8WY41
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

6238:CBG 14645
gene id: 6238:CBG_14645
uniprot id: A8XKC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 17916
gene id: 6238:CBG_17916
uniprot id: A8XS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 15980
gene id: 6238:CBG_15980
uniprot id: A8XND0
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

6238:CBG 11181
gene id: 6238:CBG_11181
uniprot id: A8XCM7
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

6238:CBG 08042
gene id: 6238:CBG_08042
uniprot id: Q5WNE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins. Also displays oxidoreductase (thioredoxin) activity (By similarity).

6238:CBG 01831
gene id: 6238:CBG_01831
uniprot id: A8WQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

6238:CBG 03313
gene id: 6238:CBG_03313
uniprot id: A8WUR4
names: Similarity
messages: Belongs to the UFD1 family.

6238:CBG 19800
gene id: 6238:CBG_19800
uniprot id: A8XWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

6238:CBG 06487
gene id: 6238:CBG_06487
uniprot id: A8X2C3
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 23091
gene id: 6238:CBG_23091
uniprot id: A8Y4Q9
names: Similarity
messages: Belongs to the actin family.

6238:CBG 03050
gene id: 6238:CBG_03050
uniprot id: A8WSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cytoplasm

6238:CBG 05885
gene id: 6238:CBG_05885
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 07355
gene id: 6238:CBG_07355
uniprot id: A8X4Y4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 00595
gene id: 6238:CBG_00595
uniprot id: A8WNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

6238:CBG 01765
gene id: 6238:CBG_01765
uniprot id: A8WQW3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 22269
gene id: 6238:CBG_22269
uniprot id: A8Y1Y0
names: Function
names: Similarity
messages: Belongs to the EAF family.
messages: Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development.

6238:CBG 14052
gene id: 6238:CBG_14052
uniprot id: A8XJ92
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 15942
gene id: 6238:CBG_15942
uniprot id: A8XNF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 19742
gene id: 6238:CBG_19742
uniprot id: P0C655
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane

6238:CBG 18195
gene id: 6238:CBG_18195
uniprot id: A8XT87
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

6238:CBG 10832
gene id: 6238:CBG_10832
uniprot id: A8XBW6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

6238:CBG 08024
gene id: 6238:CBG_08024
uniprot id: A8X5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 01610
gene id: 6238:CBG_01610
uniprot id: Q624D2
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: In contrast to other ephrins, does not seem to signal through the vab-1 receptor.
messages: May undergo proteolysis by metalloprotease sup-17 to give rise to a soluble form.
messages: Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, involved in ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting together with mab-20 and allows the formation of distinct sensory rays. Probably acts as a ligand for lad-2 to regulate axon guidance of several neurons including SDQL, SDQR, SMD and PLN neurons during neurogenesis.

6238:CBG 03025
gene id: 6238:CBG_03025
uniprot id: A8WSY5
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

6238:CBG 12178
gene id: 6238:CBG_12178
uniprot id: A8XF23
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Involved in ER-Golgi transport.

6238:CBG 23144
gene id: 6238:CBG_23144
uniprot id: E3CU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

6238:CBG 17481
gene id: 6238:CBG_17481
uniprot id: A8XR36
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03776
gene id: 6238:CBG_03776
uniprot id: A8WWP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 00960
gene id: 6238:CBG_00960
uniprot id: A8WP84
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

6238:CBG 05932
gene id: 6238:CBG_05932
uniprot id: A8X1A9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 04338
gene id: 6238:CBG_04338
uniprot id: A8WXB0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 03600
gene id: 6238:CBG_03600
uniprot id: A8WVF4
names: Subcellular Location Annotation
messages: Membrane
messages: Rough endoplasmic reticulum membrane

6238:CBG 22466
gene id: 6238:CBG_22466
uniprot id: P37164
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

6238:CBG 12264
gene id: 6238:CBG_12264
uniprot id: A8XF45
names: Similarity
messages: Belongs to the FAH family.

6238:CBG 14794
gene id: 6238:CBG_14794
uniprot id: G2J6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 07318
gene id: 6238:CBG_07318
uniprot id: A8X509
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 01388
gene id: 6238:CBG_01388
uniprot id: A8WQA7
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 05942
gene id: 6238:CBG_05942
uniprot id: A8X1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 12325
gene id: 6238:CBG_12325
uniprot id: A8XFK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 10311
gene id: 6238:CBG_10311
uniprot id: A8XAM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03029
gene id: 6238:CBG_03029
uniprot id: A8WSY6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 23361
gene id: 6238:CBG_23361
uniprot id: A8Y439
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

6238:CBG 00465
gene id: 6238:CBG_00465
uniprot id: A8WMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

6238:CBG 02573
gene id: 6238:CBG_02573
uniprot id: A8WU06
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 06530
gene id: 6238:CBG_06530
uniprot id: A8X2G2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 15250
gene id: 6238:CBG_15250
uniprot id: A8XLK4
names: Similarity
messages: Belongs to the SDO1/SBDS family.

6238:CBG 07730
gene id: 6238:CBG_07730
uniprot id: A8X476
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

6238:CBG 08257
gene id: 6238:CBG_08257
uniprot id: A8X656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 12873
gene id: 6238:CBG_12873
uniprot id: A8XFS6
names: Similarity
messages: Belongs to the peptidase M14 family.

6238:CBG 01012
gene id: 6238:CBG_01012
uniprot id: A8WP41
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 09810
gene id: 6238:CBG_09810
uniprot id: Q61JF9
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Citrate synthase is found in nearly all cells capable of oxidative metabolism.
messages: Homodimer.
messages: Mitochondrion matrix

6238:CBG 15750
gene id: 6238:CBG_15750
uniprot id: A8XMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 12204
gene id: 6238:CBG_12204
uniprot id: Q61E63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although related to the peptidase M24 family, this protein lacks conserved active site residues suggesting that it may lack peptidase activity.
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
messages: Component of the FACT complex, a stable heterodimer of spt-16 and hmg-3 or hmg-4.
messages: Nucleus

6238:CBG 05232
gene id: 6238:CBG_05232
uniprot id: A8WZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

6238:CBG 14654
gene id: 6238:CBG_14654
uniprot id: A8XKD8
names: Similarity
messages: Belongs to the GPSM family.

6238:CBG 13522
gene id: 6238:CBG_13522
uniprot id: A8XI34
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

6238:CBG 23241
gene id: 6238:CBG_23241
uniprot id: A8Y4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

6238:CBG 06805
gene id: 6238:CBG_06805
uniprot id: A8X344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

6238:CBG 17289
gene id: 6238:CBG_17289
uniprot id: A8XQR9
names: Similarity
messages: Belongs to the 14-3-3 family.

6238:CBG 19185
gene id: 6238:CBG_19185
uniprot id: A8XV10
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 07785
gene id: 6238:CBG_07785
uniprot id: A8X433
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 13217
gene id: 6238:CBG_13217
uniprot id: A8XHB4
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

6238:CBG 11388
gene id: 6238:CBG_11388
uniprot id: A8XD48
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

6238:CBG 11321
gene id: 6238:CBG_11321
uniprot id: G2J687
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

6238:CBG 09387
gene id: 6238:CBG_09387
uniprot id: A8X976
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 03006
gene id: 6238:CBG_03006
uniprot id: A8WT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

6238:CBG 09563
gene id: 6238:CBG_09563
uniprot id: A8X8T2
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 04050
gene id: 6238:CBG_04050
uniprot id: A8WW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

6238:CBG 02686
gene id: 6238:CBG_02686
uniprot id: A8WTR2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 15749
gene id: 6238:CBG_15749
uniprot id: A8XMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 21991
gene id: 6238:CBG_21991
uniprot id: A8Y1A5
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 21660
gene id: 6238:CBG_21660
uniprot id: A8Y0T5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 03298
gene id: 6238:CBG_03298
uniprot id: A8WSC9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 06959
gene id: 6238:CBG_06959
uniprot id: A8X419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

6238:CBG 03216
gene id: 6238:CBG_03216
uniprot id: A8WSJ2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 07781
gene id: 6238:CBG_07781
uniprot id: A8X436
names: Similarity
messages: Belongs to the MAX family.

6238:CBG 17472
gene id: 6238:CBG_17472
uniprot id: A8XR32
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

6238:CBG 23841
gene id: 6238:CBG_23841
uniprot id: A8WJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

6238:CBG 20945
gene id: 6238:CBG_20945
uniprot id: A8XZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 13220
gene id: 6238:CBG_13220
uniprot id: A8XHB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

6238:CBG 09764
gene id: 6238:CBG_09764
uniprot id: A8X9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

6238:CBG 13781
gene id: 6238:CBG_13781
uniprot id: A8XIP4
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 20617
gene id: 6238:CBG_20617
uniprot id: G2J6N5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 14646
gene id: 6238:CBG_14646
uniprot id: A8XKD0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 20952
gene id: 6238:CBG_20952
uniprot id: A8XZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 21102
gene id: 6238:CBG_21102
uniprot id: A8XZH1
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

6238:CBG 09422
gene id: 6238:CBG_09422
uniprot id: A8X952
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 11324
gene id: 6238:CBG_11324
uniprot id: A8XDA2
names: Similarity
messages: Belongs to the UPF0046 family.

6238:CBG 09992
gene id: 6238:CBG_09992
uniprot id: A8XA45
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 20470
gene id: 6238:CBG_20470
uniprot id: A8XXV5
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 01326
gene id: 6238:CBG_01326
uniprot id: A8WQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 02140
gene id: 6238:CBG_02140
uniprot id: Q622K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Cytoplasm
messages: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).

6238:CBG 05260
gene id: 6238:CBG_05260
uniprot id: A8WZH5
names: Similarity
messages: Belongs to the SKP1 family.

6238:CBG 11486
gene id: 6238:CBG_11486
uniprot id: A8XCW4
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 13975
gene id: 6238:CBG_13975
uniprot id: A8XIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 06867
gene id: 6238:CBG_06867
uniprot id: Q27302
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the globin family.
messages: Cytoplasm
messages: It is uncertain whether Met-1 or Met-3 is the initiator.
messages: May be a globin and may play a role in oxygen transport.

6238:CBG 18827
gene id: 6238:CBG_18827
uniprot id: A8XU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Mitochondrion inner membrane

6238:CBG 18416
gene id: 6238:CBG_18416
uniprot id: A8XT98
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 15381
gene id: 6238:CBG_15381
uniprot id: A8XM25
names: Similarity
messages: Belongs to the acid ceramidase family.

6238:CBG 13252
gene id: 6238:CBG_13252
uniprot id: A8XHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 09454
gene id: 6238:CBG_09454
uniprot id: A8X925
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 01950
gene id: 6238:CBG_01950
uniprot id: A8WRN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 13409
gene id: 6238:CBG_13409
uniprot id: A8XHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 00984
gene id: 6238:CBG_00984
uniprot id: A8WP63
names: Similarity
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.

6238:CBG 06800
gene id: 6238:CBG_06800
uniprot id: A8X339
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

6238:CBG 06368
gene id: 6238:CBG_06368
uniprot id: A8X229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 22761
gene id: 6238:CBG_22761
uniprot id: A8Y2U2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts downstream of ced-9 and caspase ced-3 to promote phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Regulates apoptosis kinetics during embryonic development. Not required for engulfment of germ cell corpses.
messages: Belongs to the XK family.
messages: Cell membrane
messages: Cleavage by ced-3 activates ced-8 function in promoting phosphatidylserine exposure at the surface of apoptotic cells.

6238:CBG 01903
gene id: 6238:CBG_01903
uniprot id: Q623D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Msh homeobox family.
messages: Nucleus
messages: Probable transcription factor needed for the proper production of touch cell precursors. Essential for embryonic morphogenesis (By similarity).

6238:CBG 04043
gene id: 6238:CBG_04043
uniprot id: A8WW26
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 15632
gene id: 6238:CBG_15632
uniprot id: A8XMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Has a role in the exit from M phase during early mitotic cell division. More specifically, thought to act by the degrading B-type cyclins that causes breakdown of nuclear envelope and exit mitosis (By similarity).
messages: Forms a homohexamer that can probably bind six kinase subunits. Interacts with cdk-1 (By similarity).
messages: Nucleus

6238:CBG 12564
gene id: 6238:CBG_12564
uniprot id: A8XG20
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

6238:CBG 01822
gene id: 6238:CBG_01822
uniprot id: A8WQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

6238:CBG 10774
gene id: 6238:CBG_10774
uniprot id: A8XBR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip. This protein is specifically required for the kinesin osm-3 to dock onto and move the IFT particles which contain these precursors.
messages: cilium

6238:CBG 15265
gene id: 6238:CBG_15265
uniprot id: A8XLI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

6238:CBG 06740
gene id: 6238:CBG_06740
uniprot id: A8X2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 19216
gene id: 6238:CBG_19216
uniprot id: A8XV36
names: Function
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.
messages: Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).

6238:CBG 23180
gene id: 6238:CBG_23180
uniprot id: A8Y4I4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 17895
gene id: 6238:CBG_17895
uniprot id: A8XS18
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 17717
gene id: 6238:CBG_17717
uniprot id: A8XRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

6238:CBG 23105
gene id: 6238:CBG_23105
uniprot id: Q60MK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Hydrolase that deubiquitinates target proteins.
messages: Nucleus

6238:CBG 12580
gene id: 6238:CBG_12580
uniprot id: A8XG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 02947
gene id: 6238:CBG_02947
uniprot id: A8WT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

6238:CBG 11303
gene id: 6238:CBG_11303
uniprot id: A8XDC0
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 17683
gene id: 6238:CBG_17683
uniprot id: Q60ZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ric-3 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with the deg-3/des-2 acetylcholine receptor.
messages: Required for maturation and cell surface expression of acetylcholine receptors.

6238:CBG 16977
gene id: 6238:CBG_16977
uniprot id: A8XQ65
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

6238:CBG 21774
gene id: 6238:CBG_21774
uniprot id: Q8I8U6
names: Function
names: Subunit
messages: Component of a complex containing fem-1, fem-2 and fem-3 (By similarity). Interacts with fem-1 and fem-2 (via N-terminus) (By similarity). Part of a E3 ubiquitin-protein ligase complex, at least composed of cul-2, elc-1, tra-1, fem-1, fem-2 and fem-3; mediates the ubiquitination and subsequent proteasomal degradation of tra-1 (By similarity). Interacts with sel-10 (By similarity). Interacts with tra-2 (PubMed:12477393).
messages: Required for male development. In XO (male) animals, fem-3 directs male differentiation in all tissues. In XX (hermaphrodite animals), it specifies the first 80 or so germ cells to be sperm. Negatively regulates male development when bound to tra-2.

6238:CBG 12309
gene id: 6238:CBG_12309
uniprot id: A8XFI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

6238:CBG 12708
gene id: 6238:CBG_12708
uniprot id: A8XGD9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 11315
gene id: 6238:CBG_11315
uniprot id: A8XDB0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 08426
gene id: 6238:CBG_08426
uniprot id: A8X6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus

6238:CBG 14653
gene id: 6238:CBG_14653
uniprot id: Q618H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS41 family.
messages: Early endosome
messages: Endosome membrane
messages: Late endosome
messages: Lysosome
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. Within the HOPS complex, contributes to the normal development of gut granules in the adult intestine. May mediate the tethering of autophagosomes with lysosomes. Has a role in the negative regulation of apoptosis. Required for uptake of exogenous dsRNA which is used in experimental RNA silencing.
messages: Probable component of the homotypic fusion and vacuole protein sorting (HOPS) complex consisting of the core class C Vps proteins vps-11, vps-16, vps-18, and which further associates with vps-33.1, vps-39 and vps-41.
messages: clathrin-coated vesicle
messages: trans-Golgi network

6238:CBG 24633
gene id: 6238:CBG_24633
uniprot id: A8WL53
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

6238:CBG 12982
gene id: 6238:CBG_12982
uniprot id: A8XGT8
names: Similarity
messages: Belongs to the Luc7 family.

6238:CBG 12905
gene id: 6238:CBG_12905
uniprot id: A8XGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 08723
gene id: 6238:CBG_08723
uniprot id: A8X790
names: Similarity
messages: Belongs to the mTERF family.

6238:CBG 23208
gene id: 6238:CBG_23208
uniprot id: A8Y4G3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 21781
gene id: 6238:CBG_21781
uniprot id: A8Y0I0
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

6238:CBG 04748
gene id: 6238:CBG_04748
uniprot id: A8WYD7
names: Similarity
messages: Belongs to the SF3A3 family.

6238:CBG 01272
gene id: 6238:CBG_01272
uniprot id: A8WQ04
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 09577
gene id: 6238:CBG_09577
uniprot id: A8X8S0
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 07944
gene id: 6238:CBG_07944
uniprot id: A8X5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

6238:CBG 19014
gene id: 6238:CBG_19014
uniprot id: A8XUK5
names: Similarity
messages: Belongs to the calponin family.

6238:CBG 15316
gene id: 6238:CBG_15316
uniprot id: A8XLX3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

6238:CBG 16933
gene id: 6238:CBG_16933
uniprot id: A8XQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

6238:CBG 06250
gene id: 6238:CBG_06250
uniprot id: A8X0J4
names: Similarity
messages: Belongs to the isochorismatase family.

6238:CBG 23153
gene id: 6238:CBG_23153
uniprot id: A8Y4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

6238:CBG 02108
gene id: 6238:CBG_02108
uniprot id: A8WS01
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 03797
gene id: 6238:CBG_03797
uniprot id: A8WWR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

6238:CBG 05717
gene id: 6238:CBG_05717
uniprot id: A8X1T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

6238:CBG 02935
gene id: 6238:CBG_02935
uniprot id: A8WT64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 13828
gene id: 6238:CBG_13828
uniprot id: A8XIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

6238:CBG 10919
gene id: 6238:CBG_10919
uniprot id: A8XC99
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 09668
gene id: 6238:CBG_09668
uniprot id: A8X8I5
names: Function
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

6238:CBG 12059
gene id: 6238:CBG_12059
uniprot id: A8XEG4
names: Similarity
messages: Belongs to the paraoxonase family.

6238:CBG 13943
gene id: 6238:CBG_13943
uniprot id: A8XIZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

6238:CBG 14140
gene id: 6238:CBG_14140
uniprot id: A8XJE4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

6238:CBG 05757
gene id: 6238:CBG_05757
uniprot id: A8X1P9
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 13973
gene id: 6238:CBG_13973
uniprot id: A8XIX2
names: Similarity
messages: Belongs to the HscB family.

6238:CBG 08020
gene id: 6238:CBG_08020
uniprot id: A8X5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

6238:CBG 04003
gene id: 6238:CBG_04003
uniprot id: A8WVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

6238:CBG 01242
gene id: 6238:CBG_01242
uniprot id: A8WPX6
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 12913
gene id: 6238:CBG_12913
uniprot id: A8XGN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

6238:CBG 23185
gene id: 6238:CBG_23185
uniprot id: A8Y4H9
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 16690
gene id: 6238:CBG_16690
uniprot id: A8XPM1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 06089
gene id: 6238:CBG_06089
uniprot id: P51558
names: Function
messages: Involved in cuticle function and is essential for normal morphological development.

6238:CBG 23360
gene id: 6238:CBG_23360
uniprot id: A8Y440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

6238:CBG 08750
gene id: 6238:CBG_08750
uniprot id: A8X7B0
names: Similarity
messages: Belongs to the BolA/IbaG family.

6238:CBG 14194
gene id: 6238:CBG_14194
uniprot id: A8XJH4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 14485
gene id: 6238:CBG_14485
uniprot id: A8XK15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 20140
gene id: 6238:CBG_20140
uniprot id: A8XX59
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 12605
gene id: 6238:CBG_12605
uniprot id: A8XG52
names: Similarity
messages: Belongs to the FAM76 family.

6238:CBG 08337
gene id: 6238:CBG_08337
uniprot id: A8X6C1
names: Similarity
messages: Belongs to the peptidase M14 family.

6238:CBG 19039
gene id: 6238:CBG_19039
uniprot id: A8XUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

6238:CBG 17353
gene id: 6238:CBG_17353
uniprot id: A8XQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

6238:CBG 11577
gene id: 6238:CBG_11577
uniprot id: A8XDJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

6238:CBG 19186
gene id: 6238:CBG_19186
uniprot id: A8XV11
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 09101
gene id: 6238:CBG_09101
uniprot id: A8X7S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

6238:CBG 16385
gene id: 6238:CBG_16385
uniprot id: A8XNJ7
names: Similarity
messages: Belongs to the intermediate filament family.

6238:CBG 02837
gene id: 6238:CBG_02837
uniprot id: A8WTE7
names: Similarity
messages: Belongs to the peptidase M13 family.

6238:CBG 04440
gene id: 6238:CBG_04440
uniprot id: A8WXK1
names: Similarity
messages: Belongs to the X(+)/potassium ATPases subunit beta family.

6238:CBG 03485
gene id: 6238:CBG_03485
uniprot id: A8WV66
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

6238:CBG 14797
gene id: 6238:CBG_14797
uniprot id: G2J6U9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 09822
gene id: 6238:CBG_09822
uniprot id: A8X9Q7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

6238:CBG 00970
gene id: 6238:CBG_00970
uniprot id: A8WP76
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

6238:CBG 05468
gene id: 6238:CBG_05468
uniprot id: A8WZY3
names: Similarity
messages: Belongs to the BLOC1S2 family.

6238:CBG 19092
gene id: 6238:CBG_19092
uniprot id: A8XUR9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 15367
gene id: 6238:CBG_15367
uniprot id: A8XM18
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 20362
gene id: 6238:CBG_20362
uniprot id: A8XXM1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

6238:CBG 07712
gene id: 6238:CBG_07712
uniprot id: A8X485
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the gob-1 trehalose phosphatase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the hydrolysis of trehalose 6-phosphate to trehalose and phosphate; prevents the accumulation of toxic levels of trehalose 6-phosphate.

6238:CBG 06466
gene id: 6238:CBG_06466
uniprot id: A8X2A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 13188
gene id: 6238:CBG_13188
uniprot id: Q17308
names: Disruption Phenotype
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Interacts with the MX regulatory domain of tra-2.
messages: Nucleus
messages: Null mutants exhibit strong masculinization and male mating behavior. XX male mutants are infertile, produce sperm from day one of adulthood, but by day three of adulthood, switch from spermatogenesis to oogenesis and produce irregular oocytes. Mutants display early somatic gonad precursor lineage defects, whereby Z1 precursors divide with reverse polarity and Z4 precursors migrate prematurely. Most animals rectify these defects to produce normal male somatic gonad. RNAi-mediated knock-down in XO male animals yields a partially feminized germ line that contains both sperm and oocytes in males, but not hermaphrodites.
messages: Only isoform a is thought to bind DNA. Zinc fingers 3, 4 and 5 are the most important for DNA binding; removal of finger 5 almost abolishes DNA binding and prevents the selection of binding sites.
messages: Plays a major role in controlling sexual phenotype (PubMed:18245372). Terminal global regulator in a well-characterized cascade of sex-determining genes (By similarity). Promotes female development (By similarity). Interacts with tra-2 to promote spermatogenesis (PubMed:11250902). Promotes spermatogenesis through the Tip60 HAT complex and by regulating the expression of genes, such as fog-3, required for male development (PubMed:24098152). Association with chromatin and at the fog-3 promoter requires wdr-5.1, and may also require wdr-5.2 (By similarity). With trr-1, activates the fog-3 gene to determine sperm/oocyte cell fate (PubMed:24098152). In hermaphrodites, binds to an intronic regulatory site in the ceh-30 gene, preventing ceh-30 transcription and thereby preventing survival of the CEM (cephalic male) sensory neurons (By similarity). Represses the expression of the transcription factor dmd-3 in hermaphrodites to govern the timing and extent of male tail tip morphogenesis (By similarity). Plays a role in controlling the sex-specific differentiation of PHC sensory neurons and represses the development of male-specific morphological features (By similarity).

6238:CBG 03988
gene id: 6238:CBG_03988
uniprot id: A8WVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

6238:CBG 12501
gene id: 6238:CBG_12501
uniprot id: A8XFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 21659
gene id: 6238:CBG_21659
uniprot id: A8Y0T6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 09073
gene id: 6238:CBG_09073
uniprot id: A8X7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

6238:CBG 23070
gene id: 6238:CBG_23070
uniprot id: A8Y4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

6238:CBG 18722
gene id: 6238:CBG_18722
uniprot id: A8XTZ6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 11934
gene id: 6238:CBG_11934
uniprot id: A8XEM6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 14873
gene id: 6238:CBG_14873
uniprot id: A8XKW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

6238:CBG 07332
gene id: 6238:CBG_07332
uniprot id: A8X4Z9
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 23842
gene id: 6238:CBG_23842
uniprot id: A8WJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

6238:CBG 11351
gene id: 6238:CBG_11351
uniprot id: A8XD79
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 02802
gene id: 6238:CBG_02802
uniprot id: A8WTH2
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 09590
gene id: 6238:CBG_09590
uniprot id: A8X8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

6238:CBG 22166
gene id: 6238:CBG_22166
uniprot id: A8Y1P8
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 02451
gene id: 6238:CBG_02451
uniprot id: A8WUA6
names: Similarity
messages: Belongs to the TTC4 family.

6238:CBG 08872
gene id: 6238:CBG_08872
uniprot id: A8X7L2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 22107
gene id: 6238:CBG_22107
uniprot id: A8Y1J4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01479
gene id: 6238:CBG_01479
uniprot id: A8WQL1
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

6238:CBG 09854
gene id: 6238:CBG_09854
uniprot id: A8X9T6
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

6238:CBG 12782
gene id: 6238:CBG_12782
uniprot id: A8XGJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

6238:CBG 13316
gene id: 6238:CBG_13316
uniprot id: G2J6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

6238:CBG 11441
gene id: 6238:CBG_11441
uniprot id: A8XD05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 18949
gene id: 6238:CBG_18949
uniprot id: A8XUE9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 12355
gene id: 6238:CBG_12355
uniprot id: A8XF84
names: Subcellular Location Annotation
messages: Nucleus speckle

6238:CBG 23428
gene id: 6238:CBG_23428
uniprot id: A8Y3X9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

6238:CBG 01972
gene id: 6238:CBG_01972
uniprot id: A8WRQ3
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 10818
gene id: 6238:CBG_10818
uniprot id: A8XBV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 21707
gene id: 6238:CBG_21707
uniprot id: A8Y0P1
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

6238:CBG 07018
gene id: 6238:CBG_07018
uniprot id: A8X3W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 16350
gene id: 6238:CBG_16350
uniprot id: A8XNM4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 20572
gene id: 6238:CBG_20572
uniprot id: A8XY41
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

6238:CBG 14574
gene id: 6238:CBG_14574
uniprot id: A8Y4R0
names: Similarity
messages: Belongs to the actin family.

6238:CBG 19035
gene id: 6238:CBG_19035
uniprot id: Q4VT42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 18931
gene id: 6238:CBG_18931
uniprot id: A8XUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 20979
gene id: 6238:CBG_20979
uniprot id: A8XZ32
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 22952
gene id: 6238:CBG_22952
uniprot id: A8Y3L0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 18037
gene id: 6238:CBG_18037
uniprot id: A8XSW1
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

6238:CBG 01646
gene id: 6238:CBG_01646
uniprot id: A8WR63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

6238:CBG 20259
gene id: 6238:CBG_20259
uniprot id: A8XXE0
names: Similarity
names: Subunit
messages: Belongs to the ODC antizyme family.
messages: Interacts with ODC1 and thereby sterically blocks ODC homodimerization.

6238:CBG 13882
gene id: 6238:CBG_13882
uniprot id: A8XJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAMOX/DASOX family.
messages: Catalyzes oxidative deamination of D-amino acids, in particular D-alanine, and could be responsible for the degradation of diet-derived D-alanine in the intestine. Acts on a variety of D-amino acids with greater preference towards those with basic and aromatic groups followed by those bearing neutral groups. Has no activity against acidic D-amino acids, L-amino acids or N-methyl-L-aspartic acid. May play a role in egg-laying events and early development.
messages: Homodimer.
messages: Peroxisome

6238:CBG 21262
gene id: 6238:CBG_21262
uniprot id: A8XZQ2
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 23681
gene id: 6238:CBG_23681
uniprot id: A8WJ26
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 09350
gene id: 6238:CBG_09350
uniprot id: A8X9A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

6238:CBG 10789
gene id: 6238:CBG_10789
uniprot id: A8XBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

6238:CBG 21753
gene id: 6238:CBG_21753
uniprot id: Q60QM8
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 22401
gene id: 6238:CBG_22401
uniprot id: A8Y256
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus

6238:CBG 20609
gene id: 6238:CBG_20609
uniprot id: G2J6N5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 03308
gene id: 6238:CBG_03308
uniprot id: Q61Z20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 07714
gene id: 6238:CBG_07714
uniprot id: Q61P40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Binds 2 copper ions per subunit.
messages: Converts tyramine into octopamine, a neurotransmitter involved in pharyngeal pumping and egg laying.
messages: synaptic vesicle

6238:CBG 19767
gene id: 6238:CBG_19767
uniprot id: A8XWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the mitochondrial contact site and cristae organizing system (MICOS) complex (also known as MINOS or MitOS complex).
messages: Belongs to the metaxin family.
messages: Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).
messages: Mitochondrion outer membrane

6238:CBG 19070
gene id: 6238:CBG_19070
uniprot id: Q60WM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex. Interacts with let-19/mdt-13. Interacts with RNA polymerase II. Interacts with mdt-28.
messages: Nucleus

6238:CBG 04391
gene id: 6238:CBG_04391
uniprot id: A8WXF6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
messages: Ca(2+)/calmodulin binding removes an autoinhibitory regulatory segment located C-terminal to the kinase domain. This releases the catalytic activity of the enzyme and makes accessible a regulatory residue Thr-284. Phosphorylation of Thr-284 by another kinase domain within the oligomeric holoenzyme keeps CaMKII active in the absence of Ca(2+)/calmodulin by preventing the rebinding of the regulatory segment to the kinase domain and by increasing the affinity of calmodulin for the enzyme. Can respond to high-frequency Ca(2+) pulses to become Ca(2+) independent (By similarity).
messages: Cytoplasm
messages: Dodecamer. Subunits are tightly packed around a central ring-shaped scaffold with extensive contacts between the regulatory segment of one kinase and the catalytic domain of another enabling cooperative activation of a subunit by the adjacent molecule. Interacts with and phosphorylates daf-16; the interaction promotes daf-16 nuclear localization. Interacts with egl-2 and tir-1. Interacts with nsy-1.
messages: Perikaryon
messages: Role in locomotion and neuronal cell fate specification. Required for the regulation of synaptic density, egg laying, defecation, and meiotic maturation. Required for viability under chronic osmotic stress in which it acts downstream of osr-1. Regulates the synaptic trafficking of glr-1. Bidirectional modulator of neurotransmitter release with negative modulatory effects mainly mediated via slo-1 activation. May suppress the functional response to an internal pacemaker, perhaps by modulating the activity of the IP3 receptor (By similarity).
messages: axon

6238:CBG 01640
gene id: 6238:CBG_01640
uniprot id: A8WR67
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 06285
gene id: 6238:CBG_06285
uniprot id: A8X1V5
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03644
gene id: 6238:CBG_03644
uniprot id: A8WVI2
names: Similarity
messages: Belongs to the yippee family.

6238:CBG 10116
gene id: 6238:CBG_10116
uniprot id: A8XAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cuticular collagen family.
messages: Membrane
messages: basement membrane

6238:CBG 18645
gene id: 6238:CBG_18645
uniprot id: A8XTT0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 18578
gene id: 6238:CBG_18578
uniprot id: A8XTM4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 05999
gene id: 6238:CBG_05999
uniprot id: A8X153
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 01690
gene id: 6238:CBG_01690
uniprot id: A8WR28
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

6238:CBG 01490
gene id: 6238:CBG_01490
uniprot id: A8WQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

6238:CBG 20214
gene id: 6238:CBG_20214
uniprot id: A8XX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Binds preferentially to the GDP-bound form of rab-11.1.
messages: Cytoplasmic granule
messages: Golgi apparatus membrane
messages: Guanine nucleotide exchange factor for Rab GTPase Rab-11.1.

6238:CBG 12179
gene id: 6238:CBG_12179
uniprot id: A8XF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm

6238:CBG 02664
gene id: 6238:CBG_02664
uniprot id: A8WTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 00049
gene id: 6238:CBG_00049
uniprot id: Q4VT26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units, alpha, beta and gamma. Interacts with gpb-1 and gpb-2.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

6238:CBG 18266
gene id: 6238:CBG_18266
uniprot id: A8XSA4
names: Similarity
messages: Belongs to the ABP1 family.

6238:CBG 09087
gene id: 6238:CBG_09087
uniprot id: A8X7U1
names: Similarity
messages: Belongs to the NUF2 family.

6238:CBG 09850
gene id: 6238:CBG_09850
uniprot id: A8X9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

6238:CBG 09830
gene id: 6238:CBG_09830
uniprot id: A8X9R4
names: Similarity
messages: Belongs to the peptidase M10A family.

6238:CBG 06344
gene id: 6238:CBG_06344
uniprot id: A8X208
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 08713
gene id: 6238:CBG_08713
uniprot id: A8X780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

6238:CBG 02998
gene id: 6238:CBG_02998
uniprot id: A8WT13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

6238:CBG 03160
gene id: 6238:CBG_03160
uniprot id: A8WSN2
names: Similarity
messages: Belongs to the SAS10 family.

6238:CBG 07766
gene id: 6238:CBG_07766
uniprot id: A8X448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 11066
gene id: 6238:CBG_11066
uniprot id: A8XCB8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02395
gene id: 6238:CBG_02395
uniprot id: A8WUF2
names: Similarity
messages: Belongs to the apolipoprotein L family.

6238:CBG 03454
gene id: 6238:CBG_03454
uniprot id: A8WV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

6238:CBG 19306
gene id: 6238:CBG_19306
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 03553
gene id: 6238:CBG_03553
uniprot id: A8WVB6
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 16594
gene id: 6238:CBG_16594
uniprot id: A8XPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 19480
gene id: 6238:CBG_19480
uniprot id: A8XVN3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

6238:CBG 08051
gene id: 6238:CBG_08051
uniprot id: A8X5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

6238:CBG 04567
gene id: 6238:CBG_04567
uniprot id: A8WXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 20834
gene id: 6238:CBG_20834
uniprot id: Q60SM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity).
messages: Nucleus

6238:CBG 03958
gene id: 6238:CBG_03958
uniprot id: A8WVU8
names: Similarity
messages: Belongs to the villin/gelsolin family.

6238:CBG 02375
gene id: 6238:CBG_02375
uniprot id: A8WUH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Belongs to the nematode receptor-like protein srg family.
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03771
gene id: 6238:CBG_03771
uniprot id: A8WWP3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

6238:CBG 12825
gene id: 6238:CBG_12825
uniprot id: A8XFP9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 10551
gene id: 6238:CBG_10551
uniprot id: A8XBD5
names: Similarity
messages: Belongs to the globin family.

6238:CBG 01314
gene id: 6238:CBG_01314
uniprot id: A8WQ43
names: Disruption Phenotype
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the large ribosomal subunit.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
messages: Cytoplasm
messages: Nucleus
messages: RNAi-mediated knockdown results in sterility and a germ cell proliferation defect.
messages: There's a functional difference between the two L11-encoding proteins in C.briggsae. rpl-11.1 plays a role in the germline whereas rpl-11.2 has a somatic function.

6238:CBG 10240
gene id: 6238:CBG_10240
uniprot id: A8XAS4
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 01493
gene id: 6238:CBG_01493
uniprot id: A8WQK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 15946
gene id: 6238:CBG_15946
uniprot id: A8XNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix
messages: This enzyme is specific for acyl chain lengths of 4 to 16.

6238:CBG 02296
gene id: 6238:CBG_02296
uniprot id: G2J6N5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 17957
gene id: 6238:CBG_17957
uniprot id: A8XSN6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

6238:CBG 07219
gene id: 6238:CBG_07219
uniprot id: A8X3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

6238:CBG 10120
gene id: 6238:CBG_10120
uniprot id: A8XAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 16142
gene id: 6238:CBG_16142
uniprot id: A8XP10
names: Similarity
messages: Belongs to the filamin family.

6238:CBG 00634
gene id: 6238:CBG_00634
uniprot id: Q627K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cytoplasm
messages: GTP-binding protein that functions in embryogenesis, cytokinesis, germline development and microtubulule cytoskeleton dynamics.
messages: centrosome

6238:CBG 17484
gene id: 6238:CBG_17484
uniprot id: A8XR33
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 00383
gene id: 6238:CBG_00383
uniprot id: A8WMY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

6238:CBG 21221
gene id: 6238:CBG_21221
uniprot id: A8XZK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

6238:CBG 01945
gene id: 6238:CBG_01945
uniprot id: A8WRM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 24606
gene id: 6238:CBG_24606
uniprot id: P41957
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Bcl-2 family.
messages: Endomembrane system
messages: Interacts with asymmetric homodimer ced-4; the interaction sequesters ced-4. Interacts with egl-1; the interaction results in ced-4 release. Interacts with dre-1; the interaction inhibits ced-9 activity, either directly or indirectly. Interacts with dct-1. May form a complex composed of ced-9, ced-4 and mac-1.
messages: Mitochondrion membrane
messages: Perikaryon
messages: Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway.
messages: Synapse

6238:CBG 01123
gene id: 6238:CBG_01123
uniprot id: A8WPL9
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 04131
gene id: 6238:CBG_04131
uniprot id: A8WVM5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

6238:CBG 07853
gene id: 6238:CBG_07853
uniprot id: A8X5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 06568
gene id: 6238:CBG_06568
uniprot id: A8X2J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

6238:CBG 05784
gene id: 6238:CBG_05784
uniprot id: A8X1M7
names: Similarity
messages: Belongs to the helicase family.

6238:CBG 02538
gene id: 6238:CBG_02538
uniprot id: A8WU33
names: Similarity
messages: Belongs to the frataxin family.

6238:CBG 21200
gene id: 6238:CBG_21200
uniprot id: A8XZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

6238:CBG 20579
gene id: 6238:CBG_20579
uniprot id: A8XY47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UVSSA family.
messages: Chromosome
messages: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes.

6238:CBG 23416
gene id: 6238:CBG_23416
uniprot id: Q60LV4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A band
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Essential for muscle contraction. Involved in ovulation likely by regulating the contraction of gonadal myoepithelial sheath cells.
messages: MHC A and MHC B are found exclusively in the body wall muscle. They co-assemble into body wall thick filament.
messages: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
messages: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
messages: myofibril

6238:CBG 24315
gene id: 6238:CBG_24315
uniprot id: A8WKF8
names: Similarity
messages: Belongs to the ANP32 family.

6238:CBG 14147
gene id: 6238:CBG_14147
uniprot id: A8XJE8
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.
messages: Belongs to the syntaxin family.

6238:CBG 01104
gene id: 6238:CBG_01104
uniprot id: A8WPK3
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 12819
gene id: 6238:CBG_12819
uniprot id: A8XFP4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

6238:CBG 07865
gene id: 6238:CBG_07865
uniprot id: A8X5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 06423
gene id: 6238:CBG_06423
uniprot id: A8X271
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 08018
gene id: 6238:CBG_08018
uniprot id: A8X5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

6238:CBG 07431
gene id: 6238:CBG_07431
uniprot id: A8X4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

6238:CBG 05064
gene id: 6238:CBG_05064
uniprot id: A8WZ33
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 01667
gene id: 6238:CBG_01667
uniprot id: A8WR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Nucleus
messages: perinuclear region

6238:CBG 06446
gene id: 6238:CBG_06446
uniprot id: A8X285
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

6238:CBG 23421
gene id: 6238:CBG_23421
uniprot id: A8Y3Y6
names: Similarity
messages: Belongs to the GPATCH11 family.

6238:CBG 06307
gene id: 6238:CBG_06307
uniprot id: A8X1X4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09612
gene id: 6238:CBG_09612
uniprot id: P90728
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 08064
gene id: 6238:CBG_08064
uniprot id: A8X5Q2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 19171
gene id: 6238:CBG_19171
uniprot id: A8XV00
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 02208
gene id: 6238:CBG_02208
uniprot id: A8WSA2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

6238:CBG 04057
gene id: 6238:CBG_04057
uniprot id: A8WW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

6238:CBG 23441
gene id: 6238:CBG_23441
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 17678
gene id: 6238:CBG_17678
uniprot id: Q60ZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: Nucleus
messages: Plays a central role in chromosome cohesion during cell division by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms.
messages: centromere

6238:CBG 11884
gene id: 6238:CBG_11884
uniprot id: A8XE83
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

6238:CBG 00670
gene id: 6238:CBG_00670
uniprot id: A8WNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 23279
gene id: 6238:CBG_23279
uniprot id: Q67EQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

6238:CBG 06080
gene id: 6238:CBG_06080
uniprot id: A8X0Y2
names: Similarity
messages: Belongs to the copine family.

6238:CBG 03802
gene id: 6238:CBG_03802
uniprot id: A8WWS1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 21042
gene id: 6238:CBG_21042
uniprot id: A8XZB4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

6238:CBG 23535
gene id: 6238:CBG_23535
uniprot id: A8Y3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 21589
gene id: 6238:CBG_21589
uniprot id: A8Y0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 02883
gene id: 6238:CBG_02883
uniprot id: A8WTA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Nucleus

6238:CBG 04296
gene id: 6238:CBG_04296
uniprot id: A8WX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

6238:CBG 24496
gene id: 6238:CBG_24496
uniprot id: A8WKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

6238:CBG 19110
gene id: 6238:CBG_19110
uniprot id: G2J6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

6238:CBG 02348
gene id: 6238:CBG_02348
uniprot id: A8WUJ1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 15718
gene id: 6238:CBG_15718
uniprot id: A8XML8
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

6238:CBG 20774
gene id: 6238:CBG_20774
uniprot id: A8XYK9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

6238:CBG 07592
gene id: 6238:CBG_07592
uniprot id: A8X4H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 13047
gene id: 6238:CBG_13047
uniprot id: A8XGY6
names: Similarity
messages: Belongs to the globin family.

6238:CBG 15188
gene id: 6238:CBG_15188
uniprot id: A8XLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

6238:CBG 04323
gene id: 6238:CBG_04323
uniprot id: A8WX91
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 00820
gene id: 6238:CBG_00820
uniprot id: A8WNX0
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

6238:CBG 23739
gene id: 6238:CBG_23739
uniprot id: A8WJ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

6238:CBG 15347
gene id: 6238:CBG_15347
uniprot id: A8XM01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

6238:CBG 00671
gene id: 6238:CBG_00671
uniprot id: A8WNB6
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

6238:CBG 15242
gene id: 6238:CBG_15242
uniprot id: A8XLL2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 05908
gene id: 6238:CBG_05908
uniprot id: A8X1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 00482
gene id: 6238:CBG_00482
uniprot id: A8WMR8
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 01814
gene id: 6238:CBG_01814
uniprot id: A8WQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 08037
gene id: 6238:CBG_08037
uniprot id: A8X5M7
names: Similarity
messages: Belongs to the GPI family.

6238:CBG 15797
gene id: 6238:CBG_15797
uniprot id: A8XMT8
names: Similarity
messages: Belongs to the GST superfamily. Omega family.

6238:CBG 12568
gene id: 6238:CBG_12568
uniprot id: A8XG24
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 19964
gene id: 6238:CBG_19964
uniprot id: A8XWU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

6238:CBG 09115
gene id: 6238:CBG_09115
uniprot id: E3CU08
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

6238:CBG 06709
gene id: 6238:CBG_06709
uniprot id: A8X2X2
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 19367
gene id: 6238:CBG_19367
uniprot id: A8XVG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

6238:CBG 19683
gene id: 6238:CBG_19683
uniprot id: A8XW68
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

6238:CBG 09160
gene id: 6238:CBG_09160
uniprot id: A8X878
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22058
gene id: 6238:CBG_22058
uniprot id: A8Y1F5
names: Similarity
messages: Belongs to the Toll-like receptor family.

6238:CBG 15663
gene id: 6238:CBG_15663
uniprot id: A8XMH5
names: Similarity
messages: Belongs to the PP2C family.

6238:CBG 12906
gene id: 6238:CBG_12906
uniprot id: A8XGM8
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 09649
gene id: 6238:CBG_09649
uniprot id: A8X8K1
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 23403
gene id: 6238:CBG_23403
uniprot id: A8Y400
names: Similarity
messages: Belongs to the dpy-30 family.

6238:CBG 17994
gene id: 6238:CBG_17994
uniprot id: A8XSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with rps-21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

6238:CBG 07632
gene id: 6238:CBG_07632
uniprot id: A8X4E6
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

6238:CBG 09583
gene id: 6238:CBG_09583
uniprot id: A8X8R4
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

6238:CBG 12702
gene id: 6238:CBG_12702
uniprot id: A8XGD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

6238:CBG 18111
gene id: 6238:CBG_18111
uniprot id: A8XT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

6238:CBG 02962
gene id: 6238:CBG_02962
uniprot id: A8WT39
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

6238:CBG 23443
gene id: 6238:CBG_23443
uniprot id: A8Y3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 05144
gene id: 6238:CBG_05144
uniprot id: A8WZ63
names: Similarity
messages: Belongs to the SNF7 family.

6238:CBG 11974
gene id: 6238:CBG_11974
uniprot id: A8XEQ5
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

6238:CBG 05357
gene id: 6238:CBG_05357
uniprot id: A8WZN9
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 23747
gene id: 6238:CBG_23747
uniprot id: A8WJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 23397
gene id: 6238:CBG_23397
uniprot id: A8Y406
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 00606
gene id: 6238:CBG_00606
uniprot id: G2J6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

6238:CBG 14923
gene id: 6238:CBG_14923
uniprot id: A8XL03
names: Similarity
messages: Belongs to the WD repeat PWP2 family.

6238:CBG 23145
gene id: 6238:CBG_23145
uniprot id: A8Y4L5
names: Similarity
messages: Belongs to the importin alpha family.

6238:CBG 12101
gene id: 6238:CBG_12101
uniprot id: A8XER5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 03935
gene id: 6238:CBG_03935
uniprot id: A8WVT0
names: Similarity
messages: Belongs to the ZC3H12 family.

6238:CBG 13937
gene id: 6238:CBG_13937
uniprot id: Q61A42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 12512
gene id: 6238:CBG_12512
uniprot id: A8XFY1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

6238:CBG 05732
gene id: 6238:CBG_05732
uniprot id: A8X1S1
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 15297
gene id: 6238:CBG_15297
uniprot id: A8XLV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus

6238:CBG 08081
gene id: 6238:CBG_08081
uniprot id: A8X5R6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

6238:CBG 02742
gene id: 6238:CBG_02742
uniprot id: A8WTL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 20987
gene id: 6238:CBG_20987
uniprot id: A8XZ40
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 23276
gene id: 6238:CBG_23276
uniprot id: A8Y4A7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15489
gene id: 6238:CBG_15489
uniprot id: A8XM74
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 13302
gene id: 6238:CBG_13302
uniprot id: A8XHI7
names: Similarity
messages: Belongs to the MIF family.

6238:CBG 02293
gene id: 6238:CBG_02293
uniprot id: A8WUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

6238:CBG 06223
gene id: 6238:CBG_06223
uniprot id: A8X0L8
names: Similarity
messages: Belongs to the SF3A2 family.

6238:CBG 06195
gene id: 6238:CBG_06195
uniprot id: A8X0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

6238:CBG 17971
gene id: 6238:CBG_17971
uniprot id: A8XSQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 23291
gene id: 6238:CBG_23291
uniprot id: A8Y494
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 07124
gene id: 6238:CBG_07124
uniprot id: A8X3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 05362
gene id: 6238:CBG_05362
uniprot id: A8WZP3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 00325
gene id: 6238:CBG_00325
uniprot id: P0C660
names: Function
names: Similarity
messages: Belongs to the PhyH family. PHYHD1 subfamily.
messages: Has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA (By similarity).

6238:CBG 04546
gene id: 6238:CBG_04546
uniprot id: A8WXW0
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 05283
gene id: 6238:CBG_05283
uniprot id: A8WZJ2
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 12877
gene id: 6238:CBG_12877
uniprot id: A8XFT0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

6238:CBG 21443
gene id: 6238:CBG_21443
uniprot id: A8Y024
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 21891
gene id: 6238:CBG_21891
uniprot id: A8Y129
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

6238:CBG 11702
gene id: 6238:CBG_11702
uniprot id: A8XDX5
names: Similarity
messages: Belongs to the GroES chaperonin family.

6238:CBG 14799
gene id: 6238:CBG_14799
uniprot id: A8XKP9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18980
gene id: 6238:CBG_18980
uniprot id: A8XUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 18639
gene id: 6238:CBG_18639
uniprot id: A8XTS5
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 08607
gene id: 6238:CBG_08607
uniprot id: A8X705
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

6238:CBG 14706
gene id: 6238:CBG_14706
uniprot id: A8XKH9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 00621
gene id: 6238:CBG_00621
uniprot id: A8WNF7
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

6238:CBG 03105
gene id: 6238:CBG_03105
uniprot id: A8WSS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 13216
gene id: 6238:CBG_13216
uniprot id: A8XHB3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

6238:CBG 01378
gene id: 6238:CBG_01378
uniprot id: A8WQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

6238:CBG 06288
gene id: 6238:CBG_06288
uniprot id: A8X1V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 12593
gene id: 6238:CBG_12593
uniprot id: A8XG44
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

6238:CBG 02512
gene id: 6238:CBG_02512
uniprot id: A8WU52
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 11065
gene id: 6238:CBG_11065
uniprot id: A8XCB7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 24766
gene id: 6238:CBG_24766
uniprot id: A8WLF5
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 04819
gene id: 6238:CBG_04819
uniprot id: A8WYJ6
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12390
gene id: 6238:CBG_12390
uniprot id: A8XFB5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

6238:CBG 07587
gene id: 6238:CBG_07587
uniprot id: A8X4H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway.

6238:CBG 19218
gene id: 6238:CBG_19218
uniprot id: A8XV38
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

6238:CBG 01701
gene id: 6238:CBG_01701
uniprot id: A8WR19
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

6238:CBG 05939
gene id: 6238:CBG_05939
uniprot id: A8X1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 04010
gene id: 6238:CBG_04010
uniprot id: A8WVZ2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 07767
gene id: 6238:CBG_07767
uniprot id: A8X447
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 09254
gene id: 6238:CBG_09254
uniprot id: A8X9I8
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 12365
gene id: 6238:CBG_12365
uniprot id: A8XF93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

6238:CBG 08167
gene id: 6238:CBG_08167
uniprot id: A8X5Z1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 01364
gene id: 6238:CBG_01364
uniprot id: A8WQ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

6238:CBG 07149
gene id: 6238:CBG_07149
uniprot id: A8X3L4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 20155
gene id: 6238:CBG_20155
uniprot id: A8XXA8
names: Similarity
messages: Belongs to the SAP18 family.

6238:CBG 09538
gene id: 6238:CBG_09538
uniprot id: A8X8V4
names: Similarity
messages: Belongs to the cullin family.

6238:CBG 20785
gene id: 6238:CBG_20785
uniprot id: A8XYL9
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

6238:CBG 01723
gene id: 6238:CBG_01723
uniprot id: A8WR00
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 16855
gene id: 6238:CBG_16855
uniprot id: A8XPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

6238:CBG 01629
gene id: 6238:CBG_01629
uniprot id: E3CTV9
names: Similarity
messages: Belongs to the peptidase M24 family.

6238:CBG 21851
gene id: 6238:CBG_21851
uniprot id: A8Y0Z3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 08012
gene id: 6238:CBG_08012
uniprot id: A8X5K8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09049
gene id: 6238:CBG_09049
uniprot id: A8X7X6
names: Similarity
messages: Belongs to the BCL7 family.

6238:CBG 07689
gene id: 6238:CBG_07689
uniprot id: A8X4A4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 08724
gene id: 6238:CBG_08724
uniprot id: A8X791
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

6238:CBG 08220
gene id: 6238:CBG_08220
uniprot id: A8X631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Microsome membrane

6238:CBG 23373
gene id: 6238:CBG_23373
uniprot id: A8Y427
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.

6238:CBG 23437
gene id: 6238:CBG_23437
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 01116
gene id: 6238:CBG_01116
uniprot id: A8WPL3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 20870
gene id: 6238:CBG_20870
uniprot id: A8XYU3
names: Similarity
messages: Belongs to the strictosidine synthase family.

6238:CBG 15267
gene id: 6238:CBG_15267
uniprot id: O61644
names: Similarity
messages: Belongs to the PP2C family.

6238:CBG 22942
gene id: 6238:CBG_22942
uniprot id: A8Y3L8
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

6238:CBG 09902
gene id: 6238:CBG_09902
uniprot id: A8X9X7
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 06112
gene id: 6238:CBG_06112
uniprot id: A8X0V6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

6238:CBG 08176
gene id: 6238:CBG_08176
uniprot id: A8X600
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

6238:CBG 06052
gene id: 6238:CBG_06052
uniprot id: A8X108
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17403
gene id: 6238:CBG_17403
uniprot id: A8XQZ6
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 16672
gene id: 6238:CBG_16672
uniprot id: A8XPA3
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

6238:CBG 01740
gene id: 6238:CBG_01740
uniprot id: Q623S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

6238:CBG 12295
gene id: 6238:CBG_12295
uniprot id: G2J6R2
names: Similarity
messages: Belongs to the GST superfamily. Omega family.

6238:CBG 19982
gene id: 6238:CBG_19982
uniprot id: A8XWV5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 09278
gene id: 6238:CBG_09278
uniprot id: A8X9G8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

6238:CBG 20157
gene id: 6238:CBG_20157
uniprot id: A8XXA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

6238:CBG 03393
gene id: 6238:CBG_03393
uniprot id: A8WUY3
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 04224
gene id: 6238:CBG_04224
uniprot id: Q61WW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP3 subfamily.
messages: Component of the Arp2/3 complex.
messages: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity).
messages: cytoskeleton

6238:CBG 20692
gene id: 6238:CBG_20692
uniprot id: A8XYE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 22219
gene id: 6238:CBG_22219
uniprot id: A8Y1T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

6238:CBG 04281
gene id: 6238:CBG_04281
uniprot id: A8WX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 18644
gene id: 6238:CBG_18644
uniprot id: A8XTS9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 16797
gene id: 6238:CBG_16797
uniprot id: A8XPU0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

6238:CBG 02609
gene id: 6238:CBG_02609
uniprot id: A8WTX6
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 06337
gene id: 6238:CBG_06337
uniprot id: A8X201
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 08364
gene id: 6238:CBG_08364
uniprot id: A8X6E0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09063
gene id: 6238:CBG_09063
uniprot id: A8X7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

6238:CBG 07596
gene id: 6238:CBG_07596
uniprot id: A8X4H2
names: Similarity
messages: Belongs to the epsin family.

6238:CBG 17860
gene id: 6238:CBG_17860
uniprot id: A8XRX9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 06798
gene id: 6238:CBG_06798
uniprot id: Q61R02
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
messages: Probable ATP-binding RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

6238:CBG 06352
gene id: 6238:CBG_06352
uniprot id: A8X215
names: Similarity
messages: Belongs to the serpin family.

6238:CBG 03179
gene id: 6238:CBG_03179
uniprot id: A8WSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

6238:CBG 22204
gene id: 6238:CBG_22204
uniprot id: A8Y1S5
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20109
gene id: 6238:CBG_20109
uniprot id: A8XX41
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

6238:CBG 00043
gene id: 6238:CBG_00043
uniprot id: A8WM72
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 10510
gene id: 6238:CBG_10510
uniprot id: A8XAZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 07339
gene id: 6238:CBG_07339
uniprot id: A8X4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

6238:CBG 06683
gene id: 6238:CBG_06683
uniprot id: A8X2U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 15760
gene id: 6238:CBG_15760
uniprot id: A8XMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

6238:CBG 06696
gene id: 6238:CBG_06696
uniprot id: A8X2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

6238:CBG 09460
gene id: 6238:CBG_09460
uniprot id: A8X921
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 17482
gene id: 6238:CBG_17482
uniprot id: A8XR35
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 13471
gene id: 6238:CBG_13471
uniprot id: A8XHN9
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 20788
gene id: 6238:CBG_20788
uniprot id: G2J716
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

6238:CBG 03481
gene id: 6238:CBG_03481
uniprot id: A8WV62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

6238:CBG 10053
gene id: 6238:CBG_10053
uniprot id: A8XA97
names: Similarity
messages: Belongs to the NATD1 family.

6238:CBG 18978
gene id: 6238:CBG_18978
uniprot id: A8XUH4
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 06640
gene id: 6238:CBG_06640
uniprot id: A8X2Q8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 01704
gene id: 6238:CBG_01704
uniprot id: A8WR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Membrane

6238:CBG 17210
gene id: 6238:CBG_17210
uniprot id: A8XQJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

6238:CBG 00135
gene id: 6238:CBG_00135
uniprot id: Q628Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Calcium-dependent mitochondrial solute carrier.
messages: Mitochondrion inner membrane

6238:CBG 22041
gene id: 6238:CBG_22041
uniprot id: A8Y1E3
names: Similarity
messages: Belongs to the eIF-2-alpha family.

6238:CBG 07164
gene id: 6238:CBG_07164
uniprot id: A8X3K4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 22372
gene id: 6238:CBG_22372
uniprot id: Q60P81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Cytoplasm

6238:CBG 18439
gene id: 6238:CBG_18439
uniprot id: A8XTB4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12675
gene id: 6238:CBG_12675
uniprot id: A8XGB4
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 09211
gene id: 6238:CBG_09211
uniprot id: A8X8C2
names: Similarity
messages: Belongs to the SIKE family.

6238:CBG 01498
gene id: 6238:CBG_01498
uniprot id: A8WQJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 17959
gene id: 6238:CBG_17959
uniprot id: A8XSN8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05883
gene id: 6238:CBG_05883
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 04059
gene id: 6238:CBG_04059
uniprot id: A8WW42
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

6238:CBG 13159
gene id: 6238:CBG_13159
uniprot id: A8XH72
names: Caution
names: Cofactor
names: Function
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Metalloprotease.

6238:CBG 15156
gene id: 6238:CBG_15156
uniprot id: A8XLT5
names: Similarity
messages: Belongs to the SKP1 family.

6238:CBG 07858
gene id: 6238:CBG_07858
uniprot id: A8X5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 23319
gene id: 6238:CBG_23319
uniprot id: A8Y474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 07426
gene id: 6238:CBG_07426
uniprot id: A8X4S8
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

6238:CBG 19778
gene id: 6238:CBG_19778
uniprot id: A8XWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

6238:CBG 23904
gene id: 6238:CBG_23904
uniprot id: A8WJJ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

6238:CBG 06117
gene id: 6238:CBG_06117
uniprot id: A8X0V3
names: Similarity
messages: Belongs to the GTR/RAG GTP-binding protein family.

6238:CBG 12012
gene id: 6238:CBG_12012
uniprot id: A8XEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 16284
gene id: 6238:CBG_16284
uniprot id: A8XNR1
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 14863
gene id: 6238:CBG_14863
uniprot id: A8XKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

6238:CBG 13922
gene id: 6238:CBG_13922
uniprot id: A8XJ11
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 05522
gene id: 6238:CBG_05522
uniprot id: A8X027
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

6238:CBG 12269
gene id: 6238:CBG_12269
uniprot id: A8XF50
names: Similarity
messages: Belongs to the TIP41 family.

6238:CBG 12746
gene id: 6238:CBG_12746
uniprot id: A8XGH2
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 10908
gene id: 6238:CBG_10908
uniprot id: A8XC89
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 15010
gene id: 6238:CBG_15010
uniprot id: A8XL72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

6238:CBG 14447
gene id: 6238:CBG_14447
uniprot id: A8XJZ4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 22306
gene id: 6238:CBG_22306
uniprot id: A8Y214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 06902
gene id: 6238:CBG_06902
uniprot id: A8X3B6
names: Similarity
messages: Belongs to the ODR-4 family.

6238:CBG 02309
gene id: 6238:CBG_02309
uniprot id: A8WUM4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

6238:CBG 21527
gene id: 6238:CBG_21527
uniprot id: A8Y0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

6238:CBG 12497
gene id: 6238:CBG_12497
uniprot id: A8XFW6
names: Similarity
messages: Belongs to the MFAP1 family.

6238:CBG 09712
gene id: 6238:CBG_09712
uniprot id: Q61JN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

6238:CBG 20483
gene id: 6238:CBG_20483
uniprot id: A8XXW7
names: Similarity
messages: Belongs to the peptidase M24B family.

6238:CBG 01662
gene id: 6238:CBG_01662
uniprot id: A8WR50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 16211
gene id: 6238:CBG_16211
uniprot id: A8XNV9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

6238:CBG 10544
gene id: 6238:CBG_10544
uniprot id: A8XBE1
names: Similarity
messages: Belongs to the group II decarboxylase family.

6238:CBG 05040
gene id: 6238:CBG_05040
uniprot id: A8WZ16
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 17662
gene id: 6238:CBG_17662
uniprot id: A8XRL0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 14472
gene id: 6238:CBG_14472
uniprot id: A8XK08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

6238:CBG 03707
gene id: 6238:CBG_03707
uniprot id: A8WWI3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

6238:CBG 19026
gene id: 6238:CBG_19026
uniprot id: A8XUL5
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 18057
gene id: 6238:CBG_18057
uniprot id: A8XSX9
names: Subcellular Location Annotation
messages: Cytoplasm

6238:CBG 20281
gene id: 6238:CBG_20281
uniprot id: A8XXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Cytoplasm
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.

6238:CBG 06131
gene id: 6238:CBG_06131
uniprot id: A8X0U3
names: Similarity
messages: Belongs to the cuticular collagen family.

6238:CBG 01648
gene id: 6238:CBG_01648
uniprot id: A8WR61
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

6238:CBG 20020
gene id: 6238:CBG_20020
uniprot id: A8XWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

6238:CBG 08611
gene id: 6238:CBG_08611
uniprot id: A8X700
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 19336
gene id: 6238:CBG_19336
uniprot id: A8XVE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

6238:CBG 06907
gene id: 6238:CBG_06907
uniprot id: G2J6L0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

6238:CBG 23418
gene id: 6238:CBG_23418
uniprot id: A8Y3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 21705
gene id: 6238:CBG_21705
uniprot id: Q60QR6
names: Similarity
messages: Belongs to the TMA7 family.

6238:CBG 20815
gene id: 6238:CBG_20815
uniprot id: A8XYP3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03552
gene id: 6238:CBG_03552
uniprot id: A8WVB5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 17370
gene id: 6238:CBG_17370
uniprot id: A8XQX3
names: Similarity
messages: Belongs to the VHL family.

6238:CBG 17740
gene id: 6238:CBG_17740
uniprot id: Q60ZM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELP4 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Component of the elongator complex.
messages: Cytoplasm
messages: Nucleus
messages: The elongator complex was originally thought to play a role in transcription elongation. However, it is no longer thought to play a direct role in this process and its primary function is thought to be in tRNA modification.

6238:CBG 18196
gene id: 6238:CBG_18196
uniprot id: A8XT88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBXO45/Fsn family.
messages: Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and ALM neurons.
messages: Component of an SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex composed of cul-1, fsn-1, rpm-1 and skr-1. Interacts (via SPRY domain) with scd-2 (via cytoplasmic domain). Interacts (via SPRY domain) with convertase egl-3 (via C-terminus).
messages: Synapse

6238:CBG 00899
gene id: 6238:CBG_00899
uniprot id: A8WPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

6238:CBG 00241
gene id: 6238:CBG_00241
uniprot id: A8WMJ2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

6238:CBG 11024
gene id: 6238:CBG_11024
uniprot id: A8XC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 00907
gene id: 6238:CBG_00907
uniprot id: Q626N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

6238:CBG 14557
gene id: 6238:CBG_14557
uniprot id: A8XK68
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

6238:CBG 02887
gene id: 6238:CBG_02887
uniprot id: A8WTA4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

6238:CBG 11576
gene id: 6238:CBG_11576
uniprot id: A8XDJ2
names: Function
names: Similarity
messages: Belongs to the peptidase C65 family.
messages: Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin (By similarity).

6238:CBG 14571
gene id: 6238:CBG_14571
uniprot id: A8XK79
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 03282
gene id: 6238:CBG_03282
uniprot id: Q61Z40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GILT family.
messages: Secreted

6238:CBG 00929
gene id: 6238:CBG_00929
uniprot id: A8WPB2
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 20801
gene id: 6238:CBG_20801
uniprot id: A8XYN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 10745
gene id: 6238:CBG_10745
uniprot id: A8XBP8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05943
gene id: 6238:CBG_05943
uniprot id: Q61T16
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.
messages: Mitochondrion

6238:CBG 12061
gene id: 6238:CBG_12061
uniprot id: A8XEG6
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

6238:CBG 05575
gene id: 6238:CBG_05575
uniprot id: A8X067
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 16733
gene id: 6238:CBG_16733
uniprot id: A8XPQ3
names: Similarity
messages: Belongs to the cytidylyltransferase family.

6238:CBG 17397
gene id: 6238:CBG_17397
uniprot id: A8XQZ0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

6238:CBG 11229
gene id: 6238:CBG_11229
uniprot id: A8XCH7
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 21106
gene id: 6238:CBG_21106
uniprot id: A8XZG7
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

6238:CBG 11304
gene id: 6238:CBG_11304
uniprot id: A8XDB9
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 12234
gene id: 6238:CBG_12234
uniprot id: Q61E36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: Nucleus
messages: mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC (By similarity).

6238:CBG 18691
gene id: 6238:CBG_18691
uniprot id: A8XTW5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 09409
gene id: 6238:CBG_09409
uniprot id: Q86FX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site (By similarity).
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. This specific G-alpha subunit plays an important role in olfaction and in cilia morphogenesis. Involved in chemotactic responses to attractants diacetyl, pyrazine, 2,4,5-trimethylthiazole, benzaldehyde, isoamyl alcohol, butanone and 2,3-pentanedione. Displays a redundant function with gpa-3 in chemotactic responses. Involved in avoidance responses to copper, sodium dodecyl sulfate and linoleic acid. Involved in osmotic avoidance and mechanosensory responses. Involved in specifying fan-like morphology of cilia of head sensory neurons AWC (By similarity).
messages: cilium
messages: dendrite

6238:CBG 13491
gene id: 6238:CBG_13491
uniprot id: Q61B55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 04022
gene id: 6238:CBG_04022
uniprot id: A8WW05
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 14199
gene id: 6238:CBG_14199
uniprot id: Q619N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family.
messages: Membrane

6238:CBG 00826
gene id: 6238:CBG_00826
uniprot id: A8WNX6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

6238:CBG 05731
gene id: 6238:CBG_05731
uniprot id: A8X1S3
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 08253
gene id: 6238:CBG_08253
uniprot id: A8X654
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 00854
gene id: 6238:CBG_00854
uniprot id: Q626S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 22 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 22775
gene id: 6238:CBG_22775
uniprot id: Q60NC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior.
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Cell membrane
messages: The channel is probably composed of at least the mec-2, mec-4, mec-6 and mec-10 subunits.

6238:CBG 23440
gene id: 6238:CBG_23440
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 06056
gene id: 6238:CBG_06056
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 00421
gene id: 6238:CBG_00421
uniprot id: A8WN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

6238:CBG 19205
gene id: 6238:CBG_19205
uniprot id: A8XV28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

6238:CBG 14607
gene id: 6238:CBG_14607
uniprot id: A8XKA2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.

6238:CBG 10871
gene id: 6238:CBG_10871
uniprot id: A8XC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 01585
gene id: 6238:CBG_01585
uniprot id: A8WRB3
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

6238:CBG 18240
gene id: 6238:CBG_18240
uniprot id: G2J6X7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

6238:CBG 09798
gene id: 6238:CBG_09798
uniprot id: A8X9N5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06202
gene id: 6238:CBG_06202
uniprot id: A8X0N8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 22507
gene id: 6238:CBG_22507
uniprot id: A8Y2F4
names: Similarity
messages: Belongs to the selenoprotein M/F family.

6238:CBG 16360
gene id: 6238:CBG_16360
uniprot id: A8XNL8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

6238:CBG 04291
gene id: 6238:CBG_04291
uniprot id: Q61WR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
messages: Required during maturation of the 40S ribosomal subunit in the nucleolus.
messages: nucleolus

6238:CBG 22036
gene id: 6238:CBG_22036
uniprot id: A8Y1E0
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

6238:CBG 07690
gene id: 6238:CBG_07690
uniprot id: A8X4A3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03655
gene id: 6238:CBG_03655
uniprot id: A8WVI9
names: Similarity
messages: Belongs to the SCO1/2 family.

6238:CBG 23219
gene id: 6238:CBG_23219
uniprot id: A8Y4F5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 00616
gene id: 6238:CBG_00616
uniprot id: A8WNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

6238:CBG 08733
gene id: 6238:CBG_08733
uniprot id: A8X796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

6238:CBG 13233
gene id: 6238:CBG_13233
uniprot id: G2J6X7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

6238:CBG 17041
gene id: 6238:CBG_17041
uniprot id: A8XQB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

6238:CBG 04946
gene id: 6238:CBG_04946
uniprot id: A8WYV4
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 12945
gene id: 6238:CBG_12945
uniprot id: G2J6S2
names: Similarity
messages: Belongs to the CDI family.

6238:CBG 19331
gene id: 6238:CBG_19331
uniprot id: A8XVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
messages: Membrane
messages: Microsome membrane

6238:CBG 13065
gene id: 6238:CBG_13065
uniprot id: A8XH00
names: Similarity
messages: Belongs to the STRIP family.

6238:CBG 21702
gene id: 6238:CBG_21702
uniprot id: A8Y0P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

6238:CBG 17478
gene id: 6238:CBG_17478
uniprot id: A8XR38
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 07937
gene id: 6238:CBG_07937
uniprot id: A8X5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. Involved in miRNA-mediated gene silencing.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

6238:CBG 03233
gene id: 6238:CBG_03233
uniprot id: Q61Z75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

6238:CBG 18935
gene id: 6238:CBG_18935
uniprot id: A8XUD9
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

6238:CBG 11160
gene id: 6238:CBG_11160
uniprot id: A8XCL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: synaptic vesicle membrane

6238:CBG 07668
gene id: 6238:CBG_07668
uniprot id: A8X4B8
names: Similarity
messages: Belongs to the FAM20 family.

6238:CBG 04031
gene id: 6238:CBG_04031
uniprot id: Q4VT38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 07116
gene id: 6238:CBG_07116
uniprot id: A8X3N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 17504
gene id: 6238:CBG_17504
uniprot id: A8XRC1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

6238:CBG 22847
gene id: 6238:CBG_22847
uniprot id: A8Y371
names: Similarity
messages: Belongs to the FAX family.

6238:CBG 16244
gene id: 6238:CBG_16244
uniprot id: A8XNU0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 14325
gene id: 6238:CBG_14325
uniprot id: A8XJR9
names: Similarity
messages: Belongs to the tektin family.

6238:CBG 00414
gene id: 6238:CBG_00414
uniprot id: A8WN13
names: Similarity
messages: Belongs to the COG2 family.

6238:CBG 05011
gene id: 6238:CBG_05011
uniprot id: A8WYZ3
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

6238:CBG 05428
gene id: 6238:CBG_05428
uniprot id: A8WZU9
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 01235
gene id: 6238:CBG_01235
uniprot id: A8WPX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 08009
gene id: 6238:CBG_08009
uniprot id: A8X5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

6238:CBG 05145
gene id: 6238:CBG_05145
uniprot id: A8WZ62
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 06300
gene id: 6238:CBG_06300
uniprot id: A8X1W7
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 09319
gene id: 6238:CBG_09319
uniprot id: A8X9D6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09014
gene id: 6238:CBG_09014
uniprot id: A8X807
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 15715
gene id: 6238:CBG_15715
uniprot id: A8XML5
names: Similarity
messages: Belongs to the peptidase M10A family.

6238:CBG 22212
gene id: 6238:CBG_22212
uniprot id: A8Y1T1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

6238:CBG 16328
gene id: 6238:CBG_16328
uniprot id: Q613L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).

6238:CBG 05041
gene id: 6238:CBG_05041
uniprot id: A8WZ17
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 18478
gene id: 6238:CBG_18478
uniprot id: A8XTE5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

6238:CBG 05029
gene id: 6238:CBG_05029
uniprot id: A8WZ06
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 16589
gene id: 6238:CBG_16589
uniprot id: A8XPJ1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17519
gene id: 6238:CBG_17519
uniprot id: A8XRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 09650
gene id: 6238:CBG_09650
uniprot id: A8X8K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 20714
gene id: 6238:CBG_20714
uniprot id: A8XYG0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 03768
gene id: 6238:CBG_03768
uniprot id: A8WWP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 16660
gene id: 6238:CBG_16660
uniprot id: A8XP91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Has a role in the homologous recombination repair (HRR) of genomic DNA during meiosis. Required for rad-51 recruitment onto ssDNA gaps generated at stalled replication fork barriers (By similarity).
messages: Interacts with brc-2 and rad-51.
messages: Nucleus

6238:CBG 23913
gene id: 6238:CBG_23913
uniprot id: A8WJK4
names: Similarity
messages: Belongs to the SRR1 family.

6238:CBG 14082
gene id: 6238:CBG_14082
uniprot id: Q619V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 10019
gene id: 6238:CBG_10019
uniprot id: A8XA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

6238:CBG 04130
gene id: 6238:CBG_04130
uniprot id: A8WVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in endocytosis. Acts by regulating the activation of rab-5 by exchanging bound GDP for free GTP at clathrin coated pits (By similarity).
messages: Belongs to the GAPVD1 family.
messages: Interacts with GDP-bound rab-5. Interacts with alpha-adaptin (By similarity).
messages: Membrane
messages: clathrin-coated vesicle

6238:CBG 04632
gene id: 6238:CBG_04632
uniprot id: Q61VZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The introduction of sperm triggers V-ATPase accumulation in proximal oocytes and induces lysosomal acidification which leads to engulfing of protein aggregates by lysosomes and subsequent clearance of the aggregates. Lysosomal acidification also leads to changes in mitochondrial morphology and function. Mitochondria in distal immature oocytes are fragmented, produce high levels of reactive oxygen species (ROS) and have high membrane potential, indicative of metabolic inactivity. In contrast, mitochondria in proximal mature oocytes are tubular with lower ROS levels and membrane potential, indicative of an active metabolic state required for aggregate mobilization before clearance. Involved in receptor-mediated endocytosis (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.

6238:CBG 23621
gene id: 6238:CBG_23621
uniprot id: A8WIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

6238:CBG 11701
gene id: 6238:CBG_11701
uniprot id: A8XDX6
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

6238:CBG 05966
gene id: 6238:CBG_05966
uniprot id: A8X178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

6238:CBG 11654
gene id: 6238:CBG_11654
uniprot id: A8XDQ7
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

6238:CBG 23735
gene id: 6238:CBG_23735
uniprot id: A8WJ63
names: Similarity
messages: Belongs to the nudE family.

6238:CBG 00356
gene id: 6238:CBG_00356
uniprot id: A8WMW5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 08382
gene id: 6238:CBG_08382
uniprot id: A8X6F5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 04751
gene id: 6238:CBG_04751
uniprot id: A8WYE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

6238:CBG 00075
gene id: 6238:CBG_00075
uniprot id: A8WM91
names: Similarity
messages: Belongs to the IL-17 family.

6238:CBG 09413
gene id: 6238:CBG_09413
uniprot id: A8X958
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22150
gene id: 6238:CBG_22150
uniprot id: A8Y1N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

6238:CBG 08511
gene id: 6238:CBG_08511
uniprot id: A8X6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

6238:CBG 06174
gene id: 6238:CBG_06174
uniprot id: A8X0R4
names: Similarity
messages: Belongs to the 14-3-3 family.

6238:CBG 14915
gene id: 6238:CBG_14915
uniprot id: Q617M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM14 family.
messages: Mitochondrion inner membrane
messages: Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GrpE, tim-44, tim-16 and tim-14.
messages: Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).

6238:CBG 21201
gene id: 6238:CBG_21201
uniprot id: A8XZM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

6238:CBG 23912
gene id: 6238:CBG_23912
uniprot id: A8WJK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 00438
gene id: 6238:CBG_00438
uniprot id: A8WN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 02483
gene id: 6238:CBG_02483
uniprot id: A8WU78
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02029
gene id: 6238:CBG_02029
uniprot id: A8WRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

6238:CBG 16984
gene id: 6238:CBG_16984
uniprot id: A8XQ72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 08759
gene id: 6238:CBG_08759
uniprot id: A8X7B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

6238:CBG 24141
gene id: 6238:CBG_24141
uniprot id: A8WK25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

6238:CBG 12081
gene id: 6238:CBG_12081
uniprot id: A8XEI3
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

6238:CBG 20970
gene id: 6238:CBG_20970
uniprot id: E3CU85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 21626
gene id: 6238:CBG_21626
uniprot id: A8Y086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

6238:CBG 08385
gene id: 6238:CBG_08385
uniprot id: A8X6F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein srb family.
messages: Membrane

6238:CBG 20771
gene id: 6238:CBG_20771
uniprot id: A8XYK6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 16606
gene id: 6238:CBG_16606
uniprot id: A8XPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Mitochondrion matrix

6238:CBG 03667
gene id: 6238:CBG_03667
uniprot id: A8WVJ8
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 04607
gene id: 6238:CBG_04607
uniprot id: A8WY17
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 10057
gene id: 6238:CBG_10057
uniprot id: A8XAA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

6238:CBG 10746
gene id: 6238:CBG_10746
uniprot id: A8XBP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 02059
gene id: 6238:CBG_02059
uniprot id: A8WRW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane

6238:CBG 15283
gene id: 6238:CBG_15283
uniprot id: A8XLH4
names: Subcellular Location Annotation
messages: perinuclear region

6238:CBG 12495
gene id: 6238:CBG_12495
uniprot id: A8XFW4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23795
gene id: 6238:CBG_23795
uniprot id: A8WJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

6238:CBG 15355
gene id: 6238:CBG_15355
uniprot id: A8XM09
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 07972
gene id: 6238:CBG_07972
uniprot id: A8X5H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Monomer. Interacts with axl-1.
messages: Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting mesoderm development. Required for normal lifespan and LiCl-induced lifespan extension (By similarity).

6238:CBG 17972
gene id: 6238:CBG_17972
uniprot id: A8XSQ1
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 03945
gene id: 6238:CBG_03945
uniprot id: A8WVT6
names: Similarity
messages: Belongs to the pyridoxine kinase family.

6238:CBG 07161
gene id: 6238:CBG_07161
uniprot id: A8X3K7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 09155
gene id: 6238:CBG_09155
uniprot id: A8X874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 12714
gene id: 6238:CBG_12714
uniprot id: A8XGE5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

6238:CBG 08351
gene id: 6238:CBG_08351
uniprot id: A8X6D1
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

6238:CBG 23704
gene id: 6238:CBG_23704
uniprot id: A8WJ41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit and an accessory subunit.
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

6238:CBG 07113
gene id: 6238:CBG_07113
uniprot id: A8X3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 12820
gene id: 6238:CBG_12820
uniprot id: A8XFP5
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 05372
gene id: 6238:CBG_05372
uniprot id: A8WZQ2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

6238:CBG 22453
gene id: 6238:CBG_22453
uniprot id: A8Y2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

6238:CBG 03712
gene id: 6238:CBG_03712
uniprot id: A8WWI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

6238:CBG 18133
gene id: 6238:CBG_18133
uniprot id: A8XT33
names: Similarity
messages: Belongs to the heat shock protein 70 family.

6238:CBG 00420
gene id: 6238:CBG_00420
uniprot id: A8WN18
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

6238:CBG 09820
gene id: 6238:CBG_09820
uniprot id: A8X9Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

6238:CBG 02260
gene id: 6238:CBG_02260
uniprot id: A8WS55
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

6238:CBG 07324
gene id: 6238:CBG_07324
uniprot id: A8X505
names: Similarity
messages: Belongs to the CCDC93 family.

6238:CBG 06926
gene id: 6238:CBG_06926
uniprot id: A8X3D7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23187
gene id: 6238:CBG_23187
uniprot id: A8Y4H7
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13546
gene id: 6238:CBG_13546
uniprot id: A8XI56
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

6238:CBG 21996
gene id: 6238:CBG_21996
uniprot id: A8Y1A9
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 15197
gene id: 6238:CBG_15197
uniprot id: A8XLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

6238:CBG 23239
gene id: 6238:CBG_23239
uniprot id: A8Y4D9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

6238:CBG 20576
gene id: 6238:CBG_20576
uniprot id: A8XY44
names: Similarity
messages: Belongs to the exportin family.

6238:CBG 22296
gene id: 6238:CBG_22296
uniprot id: A8Y204
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

6238:CBG 16681
gene id: 6238:CBG_16681
uniprot id: A8XPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

6238:CBG 17987
gene id: 6238:CBG_17987
uniprot id: A8XSR5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 23183
gene id: 6238:CBG_23183
uniprot id: A8Y4I1
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

6238:CBG 11707
gene id: 6238:CBG_11707
uniprot id: A8XDX1
names: Similarity
messages: Belongs to the SKP1 family.

6238:CBG 12621
gene id: 6238:CBG_12621
uniprot id: A8XG63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NCBP1 family.
messages: Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-1 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of ncbp-2 and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp-1 and ncbp-1 that interacts with m7GpppG-capped RNA.
messages: Nucleus

6238:CBG 16248
gene id: 6238:CBG_16248
uniprot id: A8XNT6
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

6238:CBG 01810
gene id: 6238:CBG_01810
uniprot id: A8WQR9
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 15006
gene id: 6238:CBG_15006
uniprot id: A8XL71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 05940
gene id: 6238:CBG_05940
uniprot id: A8X1A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Membrane

6238:CBG 11466
gene id: 6238:CBG_11466
uniprot id: A8XCY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 09381
gene id: 6238:CBG_09381
uniprot id: A8X981
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 04832
gene id: 6238:CBG_04832
uniprot id: A8WYK9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

6238:CBG 18189
gene id: 6238:CBG_18189
uniprot id: A8XT81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively. Directly interacts with POLR2A (By similarity).
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity).
messages: Nucleus

6238:CBG 17531
gene id: 6238:CBG_17531
uniprot id: A8XR65
names: Similarity
messages: Belongs to the cuticular collagen family.

6238:CBG 19843
gene id: 6238:CBG_19843
uniprot id: A8XWK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

6238:CBG 18361
gene id: 6238:CBG_18361
uniprot id: Q60Y65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Key enzyme in the degradation of tyrosine.

6238:CBG 11014
gene id: 6238:CBG_11014
uniprot id: A8XC17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

6238:CBG 12376
gene id: 6238:CBG_12376
uniprot id: A8XFA3
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

6238:CBG 23399
gene id: 6238:CBG_23399
uniprot id: Q60LW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).
messages: Component of the elongator complex.
messages: The elongator complex was originally thought to play a role in transcription elongation. However, it is no longer thought to play a direct role in this process and its primary function is thought to be in tRNA modification.

6238:CBG 13694
gene id: 6238:CBG_13694
uniprot id: A8XIH8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 08377
gene id: 6238:CBG_08377
uniprot id: Q61MQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 04527
gene id: 6238:CBG_04527
uniprot id: A8WXN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

6238:CBG 14970
gene id: 6238:CBG_14970
uniprot id: A8XL45
names: Similarity
messages: Belongs to the thioredoxin family.

6238:CBG 14784
gene id: 6238:CBG_14784
uniprot id: Q617Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDA1/CD39 NTPase family.
messages: Golgi apparatus membrane
messages: Seems to be able to hydrolyze ADP, UDP and GDP. Supports mig-17 glycosylation and surface expression, which is required for proper migration of distal tip cells during gonad morphogenesis (By similarity).

6238:CBG 04182
gene id: 6238:CBG_04182
uniprot id: A8WWD1
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19764
gene id: 6238:CBG_19764
uniprot id: A8XWD3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

6238:CBG 09180
gene id: 6238:CBG_09180
uniprot id: A8X890
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

6238:CBG 15104
gene id: 6238:CBG_15104
uniprot id: G2J6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

6238:CBG 20639
gene id: 6238:CBG_20639
uniprot id: Q60T36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A G protein-coupled receptor required for olfactory imprinting a requisite in ordorant response such as benzaldehyde and isoamylalcohol.
messages: Belongs to the nematode receptor-like protein sra family.
messages: Membrane

6238:CBG 06812
gene id: 6238:CBG_06812
uniprot id: A8X348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
messages: Secreted

6238:CBG 04191
gene id: 6238:CBG_04191
uniprot id: A8WWD8
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 07578
gene id: 6238:CBG_07578
uniprot id: A8X4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

6238:CBG 12713
gene id: 6238:CBG_12713
uniprot id: A8XGE4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

6238:CBG 03848
gene id: 6238:CBG_03848
uniprot id: A8WWW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 18646
gene id: 6238:CBG_18646
uniprot id: A8XTT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 00985
gene id: 6238:CBG_00985
uniprot id: A8WP62
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 20992
gene id: 6238:CBG_20992
uniprot id: A8XZ45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 10427
gene id: 6238:CBG_10427
uniprot id: A8XB68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 00741
gene id: 6238:CBG_00741
uniprot id: A8WN62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TUB family.
messages: Cell projection
messages: Cytoplasm
messages: Has a role in fat regulation independent of daf-16. Implicated in ciliar sensory function which is required for normal sensory behavior such as chemotaxis. Functions in life span control via the insulin/IGF-1 pathway. Thought to be involved in neuronal trafficking (By similarity).
messages: Interacts with rgb-3.
messages: axon
messages: cilium
messages: dendrite

6238:CBG 14680
gene id: 6238:CBG_14680
uniprot id: A8XKF8
names: Similarity
messages: Belongs to the CD36 family.

6238:CBG 07317
gene id: 6238:CBG_07317
uniprot id: A8X510
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 09137
gene id: 6238:CBG_09137
uniprot id: A8X860
names: Similarity
messages: Belongs to the CBF/MAK21 family.

6238:CBG 09040
gene id: 6238:CBG_09040
uniprot id: A8X7Y5
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 10496
gene id: 6238:CBG_10496
uniprot id: A8XAX9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 07066
gene id: 6238:CBG_07066
uniprot id: A8X3S5
names: Similarity
messages: Belongs to the Tom22 family.

6238:CBG 16008
gene id: 6238:CBG_16008
uniprot id: A8XNA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

6238:CBG 05329
gene id: 6238:CBG_05329
uniprot id: A8WZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

6238:CBG 19906
gene id: 6238:CBG_19906
uniprot id: A8XWQ0
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 07028
gene id: 6238:CBG_07028
uniprot id: A8X3V6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 17299
gene id: 6238:CBG_17299
uniprot id: A8XQS6
names: Similarity
messages: Belongs to the NIBP family.

6238:CBG 08987
gene id: 6238:CBG_08987
uniprot id: A8X828
names: Similarity
messages: Belongs to the PAR3 family.

6238:CBG 11442
gene id: 6238:CBG_11442
uniprot id: A8XD04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 12920
gene id: 6238:CBG_12920
uniprot id: A8XGP0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

6238:CBG 13105
gene id: 6238:CBG_13105
uniprot id: A8XH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I33 family.
messages: Secreted

6238:CBG 08835
gene id: 6238:CBG_08835
uniprot id: A8X7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

6238:CBG 11415
gene id: 6238:CBG_11415
uniprot id: A8XD29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

6238:CBG 12425
gene id: 6238:CBG_12425
uniprot id: A8XFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 13602
gene id: 6238:CBG_13602
uniprot id: A8XIA2
names: Similarity
messages: Belongs to the VPS25 family.

6238:CBG 11305
gene id: 6238:CBG_11305
uniprot id: A8XDB8
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 12397
gene id: 6238:CBG_12397
uniprot id: A8XFC1
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 05336
gene id: 6238:CBG_05336
uniprot id: A8WZM1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus

6238:CBG 07938
gene id: 6238:CBG_07938
uniprot id: A8X5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

6238:CBG 08925
gene id: 6238:CBG_08925
uniprot id: A8X7P9
names: Similarity
messages: Belongs to the actin family.

6238:CBG 20343
gene id: 6238:CBG_20343
uniprot id: G2J711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

6238:CBG 07862
gene id: 6238:CBG_07862
uniprot id: A8X5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 10165
gene id: 6238:CBG_10165
uniprot id: A8XAI9
names: Subcellular Location Annotation
messages: centromere

6238:CBG 24278
gene id: 6238:CBG_24278
uniprot id: A8WKD1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

6238:CBG 04122
gene id: 6238:CBG_04122
uniprot id: Q61X54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 13503
gene id: 6238:CBG_13503
uniprot id: A8XI17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

6238:CBG 12466
gene id: 6238:CBG_12466
uniprot id: Q61DI9
names: Function
names: Similarity
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB.

6238:CBG 15975
gene id: 6238:CBG_15975
uniprot id: A8XND4
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

6238:CBG 00844
gene id: 6238:CBG_00844
uniprot id: A8WPH3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 11770
gene id: 6238:CBG_11770
uniprot id: A8XE06
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 18001
gene id: 6238:CBG_18001
uniprot id: Q93148
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT6 family.
messages: Interacts with glp-1 and lin-12.
messages: May regulate transcriptional elongation by RNA polymerase II. May be required for several aspects of morphogenesis of C.briggsae, including regulation of division in the germline and gut and specification of ventral-uterine precursor cell fate (By similarity).
messages: Nucleus

6238:CBG 20773
gene id: 6238:CBG_20773
uniprot id: A8XYK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with BRAWNIN.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 17872
gene id: 6238:CBG_17872
uniprot id: A8XRZ6
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 08803
gene id: 6238:CBG_08803
uniprot id: A8X7F4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 04072
gene id: 6238:CBG_04072
uniprot id: A8WW52
names: Subunit
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

6238:CBG 17279
gene id: 6238:CBG_17279
uniprot id: A8XQR4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

6238:CBG 23120
gene id: 6238:CBG_23120
uniprot id: A8Y4N3
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 08212
gene id: 6238:CBG_08212
uniprot id: A8X623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 22719
gene id: 6238:CBG_22719
uniprot id: A8Y310
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03817
gene id: 6238:CBG_03817
uniprot id: A8WWT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

6238:CBG 16767
gene id: 6238:CBG_16767
uniprot id: A8XPS2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 13200
gene id: 6238:CBG_13200
uniprot id: A8XHA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Membrane

6238:CBG 14284
gene id: 6238:CBG_14284
uniprot id: A8XJP0
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 20655
gene id: 6238:CBG_20655
uniprot id: A8XYA9
names: Similarity
messages: Belongs to the RRP12 family.

6238:CBG 15175
gene id: 6238:CBG_15175
uniprot id: A8XLR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with an ATP-specific beta subunit, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with a GTP-specific beta subunit forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

6238:CBG 09943
gene id: 6238:CBG_09943
uniprot id: A8XA04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 00451
gene id: 6238:CBG_00451
uniprot id: A8WN44
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10720
gene id: 6238:CBG_10720
uniprot id: A8XBM5
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 00622
gene id: 6238:CBG_00622
uniprot id: A8WNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 10062
gene id: 6238:CBG_10062
uniprot id: Q61IU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer. Part of the multisubunit TRAPP (transport protein particle) complex.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi. Required for the systemic spread of the RNAi response.
messages: cis-Golgi network

6238:CBG 03254
gene id: 6238:CBG_03254
uniprot id: A8WSG2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

6238:CBG 18585
gene id: 6238:CBG_18585
uniprot id: A8XTM9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

6238:CBG 03702
gene id: 6238:CBG_03702
uniprot id: A8WWI0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

6238:CBG 09048
gene id: 6238:CBG_09048
uniprot id: A8X7X7
names: Similarity
names: Subunit
messages: Belongs to the dynactin subunit 2 family.
messages: Subunit of dynactin, a multiprotein complex associated with dynein.

6238:CBG 04292
gene id: 6238:CBG_04292
uniprot id: A8WX61
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

6238:CBG 02877
gene id: 6238:CBG_02877
uniprot id: G2J6F0
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 10464
gene id: 6238:CBG_10464
uniprot id: A8XBA0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 03541
gene id: 6238:CBG_03541
uniprot id: A8WVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus

6238:CBG 22844
gene id: 6238:CBG_22844
uniprot id: A8Y368
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 11989
gene id: 6238:CBG_11989
uniprot id: A8XEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

6238:CBG 20736
gene id: 6238:CBG_20736
uniprot id: A8XYH5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

6238:CBG 03681
gene id: 6238:CBG_03681
uniprot id: A8WVK9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

6238:CBG 00730
gene id: 6238:CBG_00730
uniprot id: A8WN72
names: Similarity
messages: Belongs to the RdRP family.

6238:CBG 21866
gene id: 6238:CBG_21866
uniprot id: Q60QD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Has a role in spindle assembly which acts in the progression through mitosis during embryogenesis. Required for fertility (By similarity).
messages: Hexamer.
messages: Nucleus

6238:CBG 11840
gene id: 6238:CBG_11840
uniprot id: A8XE50
names: Similarity
messages: Belongs to the insulin family.

6238:CBG 08544
gene id: 6238:CBG_08544
uniprot id: Q61MC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 02254
gene id: 6238:CBG_02254
uniprot id: G2J682
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 18125
gene id: 6238:CBG_18125
uniprot id: A8XT29
names: Similarity
messages: Belongs to the thioesterase PaaI family.

6238:CBG 11203
gene id: 6238:CBG_11203
uniprot id: A8XCP8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09060
gene id: 6238:CBG_09060
uniprot id: A8X7W5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

6238:CBG 05884
gene id: 6238:CBG_05884
uniprot id: G2J6I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 19432
gene id: 6238:CBG_19432
uniprot id: A8XVL7
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

6238:CBG 03555
gene id: 6238:CBG_03555
uniprot id: A8WVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

6238:CBG 04574
gene id: 6238:CBG_04574
uniprot id: A8WXY8
names: Similarity
messages: Belongs to the cyclin family.

6238:CBG 00031
gene id: 6238:CBG_00031
uniprot id: A8WM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 07468
gene id: 6238:CBG_07468
uniprot id: G2J6L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 08270
gene id: 6238:CBG_08270
uniprot id: A8X667
names: Similarity
messages: Belongs to the helicase family. RLR subfamily.

6238:CBG 09959
gene id: 6238:CBG_09959
uniprot id: A8XA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

6238:CBG 18828
gene id: 6238:CBG_18828
uniprot id: A8XU72
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02963
gene id: 6238:CBG_02963
uniprot id: A8WT38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

6238:CBG 03420
gene id: 6238:CBG_03420
uniprot id: A8WV08
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 22509
gene id: 6238:CBG_22509
uniprot id: A8Y2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

6238:CBG 12437
gene id: 6238:CBG_12437
uniprot id: A8XFF8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 09971
gene id: 6238:CBG_09971
uniprot id: A8XA25
names: Similarity
messages: Belongs to the peptidase C19 family.

6238:CBG 17477
gene id: 6238:CBG_17477
uniprot id: A8XR39
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06617
gene id: 6238:CBG_06617
uniprot id: Q61RF0
names: Similarity
messages: Belongs to the RRP15 family.

6238:CBG 01522
gene id: 6238:CBG_01522
uniprot id: A8WQH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

6238:CBG 01103
gene id: 6238:CBG_01103
uniprot id: A8WPK2
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 13601
gene id: 6238:CBG_13601
uniprot id: A8XIA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

6238:CBG 12341
gene id: 6238:CBG_12341
uniprot id: A8XFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

6238:CBG 13312
gene id: 6238:CBG_13312
uniprot id: A8XHJ7
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

6238:CBG 06639
gene id: 6238:CBG_06639
uniprot id: A8X2Q7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

6238:CBG 09341
gene id: 6238:CBG_09341
uniprot id: A8X9B8
names: Similarity
messages: Belongs to the Gfa family.

6238:CBG 01051
gene id: 6238:CBG_01051
uniprot id: A8WP06
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
messages: Membrane
messages: cis-Golgi network membrane

6238:CBG 05342
gene id: 6238:CBG_05342
uniprot id: A8WZM5
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 20079
gene id: 6238:CBG_20079
uniprot id: A8XX16
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 05238
gene id: 6238:CBG_05238
uniprot id: A8WZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

6238:CBG 24605
gene id: 6238:CBG_24605
uniprot id: A8WL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 06794
gene id: 6238:CBG_06794
uniprot id: A8X333
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 12097
gene id: 6238:CBG_12097
uniprot id: A8XEJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

6238:CBG 07948
gene id: 6238:CBG_07948
uniprot id: A8X5F7
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

6238:CBG 20497
gene id: 6238:CBG_20497
uniprot id: A8XXY0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

6238:CBG 02284
gene id: 6238:CBG_02284
uniprot id: A8WUP5
names: Similarity
messages: Belongs to the SURF6 family.

6238:CBG 02999
gene id: 6238:CBG_02999
uniprot id: A8WT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

6238:CBG 22831
gene id: 6238:CBG_22831
uniprot id: A8Y357
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 04612
gene id: 6238:CBG_04612
uniprot id: A8WY22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

6238:CBG 12233
gene id: 6238:CBG_12233
uniprot id: A8XEX6
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12686
gene id: 6238:CBG_12686
uniprot id: A8XGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 10985
gene id: 6238:CBG_10985
uniprot id: A8XBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta-catenin family.
messages: Cell junction
messages: Cytoplasm
messages: Interacts with apr-1, axl-1, daf-16, lin-23, and pop-1 (via acidic region in N-terminus 1-44). Interacts (via ARM repeats) with pry-1 (By similarity).
messages: Membrane
messages: Nucleus
messages: Participates in the Wnt signaling pathway which affects cell fate and may regulate the stem cell divisions of seam cells during larval development. Functions as a transcriptional activator but is dependent on the interaction with pop-1. Involved in maintaining lin-39 Hox expression and regulating glr-1 abundance at the synapses. Required for mab-5 expression during Q neuroblast migration and for oxidative stress-induced daf-16 signaling. Has roles in egg laying, vulva precursor cell fate determination, Q neuroblast migration, posterior ectodermal cell P12 specification, movement, body length, male tail development and dauer induction. Functionally redundant to wrm-1 and hmp-2 (By similarity).

6238:CBG 12806
gene id: 6238:CBG_12806
uniprot id: A8XFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

6238:CBG 00301
gene id: 6238:CBG_00301
uniprot id: A8WMN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

6238:CBG 21613
gene id: 6238:CBG_21613
uniprot id: A8Y075
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 11454
gene id: 6238:CBG_11454
uniprot id: A8XCZ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 14328
gene id: 6238:CBG_14328
uniprot id: A8XJS2
names: Similarity
messages: Belongs to the Mo25 family.

6238:CBG 03813
gene id: 6238:CBG_03813
uniprot id: A8WWT2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 06906
gene id: 6238:CBG_06906
uniprot id: G2J6L0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

6238:CBG 18374
gene id: 6238:CBG_18374
uniprot id: A8XSJ8
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

6238:CBG 12670
gene id: 6238:CBG_12670
uniprot id: A8XGA9
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

6238:CBG 20784
gene id: 6238:CBG_20784
uniprot id: A8XYL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

6238:CBG 15681
gene id: 6238:CBG_15681
uniprot id: A8XMI7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 16863
gene id: 6238:CBG_16863
uniprot id: A8XPY9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 18871
gene id: 6238:CBG_18871
uniprot id: A8XU89
names: Similarity
names: Subunit
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Homodimer.

6238:CBG 09846
gene id: 6238:CBG_09846
uniprot id: A8X9S8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 14053
gene id: 6238:CBG_14053
uniprot id: A8XJ93
names: Disruption Phenotype
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the large ribosomal subunit.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
messages: Cytoplasm
messages: Nucleus
messages: RNAi-mediated knockdown results in few viable embryos and as a result few live progeny and defective growth.
messages: There's a functional difference between the two L11-encoding proteins in C.briggsae. rpl-11.1 plays a role in the germline whereas rpl-11.2 has a somatic function.

6238:CBG 16826
gene id: 6238:CBG_16826
uniprot id: Q612A4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Cytoplasm
messages: Membrane
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity). Has roles in embryogenesis and ovulation (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR (By similarity). Interacts with V-type proton ATPase subunits a1 unc-32, a2 vha-5 and a3 vha-6 (By similarity).
messages: Vha-11 and vha-3 are transcribed on a dicistronic transcript where vha-3 is the upstream transcript and vha-11 the downstream.

6238:CBG 20719
gene id: 6238:CBG_20719
uniprot id: E3CU80
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 11211
gene id: 6238:CBG_11211
uniprot id: A8XCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

6238:CBG 12232
gene id: 6238:CBG_12232
uniprot id: A8XEX7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01500
gene id: 6238:CBG_01500
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 08898
gene id: 6238:CBG_08898
uniprot id: A8X7M9
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 23184
gene id: 6238:CBG_23184
uniprot id: A8Y4I0
names: Similarity
messages: Belongs to the PP1 inhibitor family.

6238:CBG 01947
gene id: 6238:CBG_01947
uniprot id: Q622Z7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
messages: Specifically phosphorylates the activated forms of G protein-coupled receptors.

6238:CBG 06825
gene id: 6238:CBG_06825
uniprot id: A8X357
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Homodimer.

6238:CBG 04188
gene id: 6238:CBG_04188
uniprot id: A8WWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

6238:CBG 23295
gene id: 6238:CBG_23295
uniprot id: A8Y492
names: Similarity
messages: Belongs to the SNW family.

6238:CBG 22132
gene id: 6238:CBG_22132
uniprot id: A8Y1L5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 09462
gene id: 6238:CBG_09462
uniprot id: A8X919
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

6238:CBG 16981
gene id: 6238:CBG_16981
uniprot id: A8XQ69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 18418
gene id: 6238:CBG_18418
uniprot id: A8XTA0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 22525
gene id: 6238:CBG_22525
uniprot id: A8Y2H1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 13074
gene id: 6238:CBG_13074
uniprot id: A8XH09
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 09156
gene id: 6238:CBG_09156
uniprot id: A8X875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 13115
gene id: 6238:CBG_13115
uniprot id: A8XH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

6238:CBG 06367
gene id: 6238:CBG_06367
uniprot id: G2J6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 18940
gene id: 6238:CBG_18940
uniprot id: A8XUE4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

6238:CBG 23420
gene id: 6238:CBG_23420
uniprot id: A8Y3Y7
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

6238:CBG 21020
gene id: 6238:CBG_21020
uniprot id: A8XZ67
names: Similarity
messages: Belongs to the REXO4 family.

6238:CBG 22316
gene id: 6238:CBG_22316
uniprot id: A8Y221
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09044
gene id: 6238:CBG_09044
uniprot id: A8X7Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 20690
gene id: 6238:CBG_20690
uniprot id: A8XYD8
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 03052
gene id: 6238:CBG_03052
uniprot id: A8WSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cytoplasm

6238:CBG 03807
gene id: 6238:CBG_03807
uniprot id: A8WWS6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

6238:CBG 08178
gene id: 6238:CBG_08178
uniprot id: Q5WN23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Membrane

6238:CBG 14858
gene id: 6238:CBG_14858
uniprot id: A8XKU8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 13750
gene id: 6238:CBG_13750
uniprot id: A8XIL6
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 07946
gene id: 6238:CBG_07946
uniprot id: A8X5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

6238:CBG 20548
gene id: 6238:CBG_20548
uniprot id: A8XY21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 11138
gene id: 6238:CBG_11138
uniprot id: A8XCJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03788
gene id: 6238:CBG_03788
uniprot id: A8WWQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Regulates cilium formation and structure.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

6238:CBG 20738
gene id: 6238:CBG_20738
uniprot id: A8XYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 14267
gene id: 6238:CBG_14267
uniprot id: A8XJM7
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

6238:CBG 11909
gene id: 6238:CBG_11909
uniprot id: A8XEK6
names: Similarity
messages: Belongs to the MIF family.

6238:CBG 07470
gene id: 6238:CBG_07470
uniprot id: A8X4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Chromosome
messages: Nucleus

6238:CBG 11023
gene id: 6238:CBG_11023
uniprot id: A8XC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

6238:CBG 06109
gene id: 6238:CBG_06109
uniprot id: A8X0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

6238:CBG 16435
gene id: 6238:CBG_16435
uniprot id: A8XP28
names: Similarity
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

6238:CBG 09373
gene id: 6238:CBG_09373
uniprot id: A8X989
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10201
gene id: 6238:CBG_10201
uniprot id: A8XAV3
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 03435
gene id: 6238:CBG_03435
uniprot id: A8WV22
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

6238:CBG 14577
gene id: 6238:CBG_14577
uniprot id: A8XK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

6238:CBG 17173
gene id: 6238:CBG_17173
uniprot id: A8XQM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

6238:CBG 12990
gene id: 6238:CBG_12990
uniprot id: A8XGU5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 14965
gene id: 6238:CBG_14965
uniprot id: A8XL40
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

6238:CBG 21257
gene id: 6238:CBG_21257
uniprot id: A8XZP7
names: Similarity
messages: Belongs to the BolA/IbaG family.

6238:CBG 21683
gene id: 6238:CBG_21683
uniprot id: A8Y0R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 16511
gene id: 6238:CBG_16511
uniprot id: A8XPD4
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

6238:CBG 03579
gene id: 6238:CBG_03579
uniprot id: A8WVD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 12247
gene id: 6238:CBG_12247
uniprot id: A8XF32
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23353
gene id: 6238:CBG_23353
uniprot id: A8Y444
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

6238:CBG 10828
gene id: 6238:CBG_10828
uniprot id: A8XBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

6238:CBG 24373
gene id: 6238:CBG_24373
uniprot id: A8WKK1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 17892
gene id: 6238:CBG_17892
uniprot id: A8XS15
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

6238:CBG 18251
gene id: 6238:CBG_18251
uniprot id: A8XS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

6238:CBG 02480
gene id: 6238:CBG_02480
uniprot id: A8WU80
names: Similarity
messages: Belongs to the thioesterase PaaI family.

6238:CBG 16309
gene id: 6238:CBG_16309
uniprot id: A8XNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Mitochondrion

6238:CBG 14166
gene id: 6238:CBG_14166
uniprot id: A8XJF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

6238:CBG 22101
gene id: 6238:CBG_22101
uniprot id: A8Y1J0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

6238:CBG 13872
gene id: 6238:CBG_13872
uniprot id: A8XJ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

6238:CBG 08327
gene id: 6238:CBG_08327
uniprot id: A8X6B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

6238:CBG 01029
gene id: 6238:CBG_01029
uniprot id: A8WP26
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 19114
gene id: 6238:CBG_19114
uniprot id: G2J6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

6238:CBG 06179
gene id: 6238:CBG_06179
uniprot id: A8X0Q9
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 10032
gene id: 6238:CBG_10032
uniprot id: A8XA80
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Cleaved at the onset of meiotic anaphase I, likely by separase sep-1.
messages: Forms a nucleosome-like histone octamer containing two molecules each of H2A, H2B, cpar-1 and H4 assembled in one cpar-1-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Not required for chromosome segregation during meiosis.
messages: Nucleus

6238:CBG 16497
gene id: 6238:CBG_16497
uniprot id: A8XPC5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19184
gene id: 6238:CBG_19184
uniprot id: A8XV09
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 19018
gene id: 6238:CBG_19018
uniprot id: A8XUK8
names: Subcellular Location Annotation
messages: Endosome
messages: Vesicle

6238:CBG 18132
gene id: 6238:CBG_18132
uniprot id: A8XT32
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

6238:CBG 09713
gene id: 6238:CBG_09713
uniprot id: A8X8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

6238:CBG 02290
gene id: 6238:CBG_02290
uniprot id: A8WUN9
names: Similarity
messages: Belongs to the peptidase C48 family.

6238:CBG 21343
gene id: 6238:CBG_21343
uniprot id: A8XZW1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

6238:CBG 15988
gene id: 6238:CBG_15988
uniprot id: A8XNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

6238:CBG 17747
gene id: 6238:CBG_17747
uniprot id: A8XRE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 19287
gene id: 6238:CBG_19287
uniprot id: A8XV96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Cell membrane
messages: Mediates sugar transport across membranes.
messages: Membrane

6238:CBG 02978
gene id: 6238:CBG_02978
uniprot id: A8WT26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Forms part of complex II containing four subunits: a flavoprotein (FP), an iron-sulfur protein (IP) and a cytochrome b composed of a large and a small subunit.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

6238:CBG 08494
gene id: 6238:CBG_08494
uniprot id: A8X6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

6238:CBG 15022
gene id: 6238:CBG_15022
uniprot id: A8XL80
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 14280
gene id: 6238:CBG_14280
uniprot id: A8XJN7
names: Disruption Phenotype
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNAi-mediated knockdown by injection into adults causes almost half of their progeny to terminally arrest at the larval L1 stage and the rest developed into fertile adults (PubMed:11044397). Simultaneous knockdown of forkhead gene pes-1 causes 8% embryonic lethality and 80% of progeny to arrest at larval L1 stage (PubMed:11044397).
messages: Transcription factor (By similarity). Plays a role in embryogenesis and later development, perhaps acting redundantly with forkhead protein pes-1 (PubMed:11044397).

6238:CBG 18276
gene id: 6238:CBG_18276
uniprot id: A8XSB4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17377
gene id: 6238:CBG_17377
uniprot id: A8XQX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

6238:CBG 04501
gene id: 6238:CBG_04501
uniprot id: A8WXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

6238:CBG 02633
gene id: 6238:CBG_02633
uniprot id: A8WTV5
names: Similarity
messages: Belongs to the ATG8 family.

6238:CBG 10898
gene id: 6238:CBG_10898
uniprot id: A8XC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane
messages: Preautophagosomal structure membrane

6238:CBG 09058
gene id: 6238:CBG_09058
uniprot id: A8X7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

6238:CBG 23511
gene id: 6238:CBG_23511
uniprot id: A8Y3R2
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

6238:CBG 12758
gene id: 6238:CBG_12758
uniprot id: A8XGI3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 12386
gene id: 6238:CBG_12386
uniprot id: A8XFB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 20451
gene id: 6238:CBG_20451
uniprot id: A8XXT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

6238:CBG 06566
gene id: 6238:CBG_06566
uniprot id: A8X2J7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

6238:CBG 10894
gene id: 6238:CBG_10894
uniprot id: A8XC78
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

6238:CBG 01978
gene id: 6238:CBG_01978
uniprot id: A8WRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 01160
gene id: 6238:CBG_01160
uniprot id: A8WPQ2
names: Similarity
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

6238:CBG 11527
gene id: 6238:CBG_11527
uniprot id: A8XCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

6238:CBG 17384
gene id: 6238:CBG_17384
uniprot id: A8XQY3
names: Similarity
messages: Belongs to the intermediate filament family.

6238:CBG 01023
gene id: 6238:CBG_01023
uniprot id: A8WP32
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 06028
gene id: 6238:CBG_06028
uniprot id: A8X125
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

6238:CBG 01526
gene id: 6238:CBG_01526
uniprot id: A8WQH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxidase family. XPO subfamily.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group covalently per subunit.
messages: Catalyzes the two-electron oxidation of bromide by hydrogen peroxide and generates hypobromite as a reactive intermediate which mediates the formation of sulfilimine cross-links between methionine and hydroxylysine residues within an uncross-linked collagen IV NC1 hexamer (By similarity). Plays a role in the attachment of tissues and in axonal guidance during early developmental stages (By similarity). May functionally antagonize the peroxidasin pxn-2 to maintain neuronal development (By similarity).
messages: extracellular matrix

6238:CBG 18465
gene id: 6238:CBG_18465
uniprot id: A8XTD7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

6238:CBG 23480
gene id: 6238:CBG_23480
uniprot id: A8Y3T7
names: Similarity
messages: Belongs to the FAX family.

6238:CBG 18826
gene id: 6238:CBG_18826
uniprot id: A8XU70
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02839
gene id: 6238:CBG_02839
uniprot id: A8WTE5
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

6238:CBG 04584
gene id: 6238:CBG_04584
uniprot id: A8WXZ8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 07605
gene id: 6238:CBG_07605
uniprot id: A8X4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 03927
gene id: 6238:CBG_03927
uniprot id: A8WVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

6238:CBG 17670
gene id: 6238:CBG_17670
uniprot id: A8XRK1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 14299
gene id: 6238:CBG_14299
uniprot id: A8XJQ1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 06988
gene id: 6238:CBG_06988
uniprot id: A8X3Z3
names: Similarity
messages: Belongs to the Luc7 family.

6238:CBG 09151
gene id: 6238:CBG_09151
uniprot id: A8X870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

6238:CBG 05062
gene id: 6238:CBG_05062
uniprot id: A8WZ31
names: Similarity
messages: Belongs to the peptidase S10 family.

6238:CBG 14495
gene id: 6238:CBG_14495
uniprot id: A8XK22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

6238:CBG 03401
gene id: 6238:CBG_03401
uniprot id: A8WUZ0
names: Similarity
messages: Belongs to the AAA ATPase family.

6238:CBG 05282
gene id: 6238:CBG_05282
uniprot id: A8WZJ1
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 19514
gene id: 6238:CBG_19514
uniprot id: A8XVS8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02501
gene id: 6238:CBG_02501
uniprot id: A8WU63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

6238:CBG 11988
gene id: 6238:CBG_11988
uniprot id: A8XEA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).

6238:CBG 01959
gene id: 6238:CBG_01959
uniprot id: A8WRP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 07320
gene id: 6238:CBG_07320
uniprot id: A8X507
names: Similarity
messages: Belongs to the cytochrome b5 family.

6238:CBG 18146
gene id: 6238:CBG_18146
uniprot id: A8XT44
names: Similarity
messages: Belongs to the CutC family.

6238:CBG 08424
gene id: 6238:CBG_08424
uniprot id: A8X6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

6238:CBG 09016
gene id: 6238:CBG_09016
uniprot id: Q61LA1
names: Similarity
messages: Belongs to the TTC21 family.

6238:CBG 06064
gene id: 6238:CBG_06064
uniprot id: A8X0Z6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03570
gene id: 6238:CBG_03570
uniprot id: A8WVD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the syntaxin family.
messages: Interacts with unc-18.
messages: Membrane
messages: Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt.

6238:CBG 12220
gene id: 6238:CBG_12220
uniprot id: A8XEY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

6238:CBG 16983
gene id: 6238:CBG_16983
uniprot id: G2J6A4
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02731
gene id: 6238:CBG_02731
uniprot id: A1XDB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: May be involved in pre-mRNA splicing.
messages: Nucleus

6238:CBG 17483
gene id: 6238:CBG_17483
uniprot id: A8XR34
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 14500
gene id: 6238:CBG_14500
uniprot id: A8XK26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in tubular endoplasmic reticulum network formation and maintenance (By similarity). May be involved in central nervous system development. Has a presynaptic role in neurotransmission. Likely to operate in synaptogenesis by regulating vesicular transport or localization. Required for correct localization of rab-3 and snb-1 (By similarity).

6238:CBG 23461
gene id: 6238:CBG_23461
uniprot id: A8Y3V1
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 17669
gene id: 6238:CBG_17669
uniprot id: A8XRK2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 05998
gene id: 6238:CBG_05998
uniprot id: A8X154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 20397
gene id: 6238:CBG_20397
uniprot id: A8XXP4
names: Similarity
messages: Belongs to the rtf2 family.

6238:CBG 04067
gene id: 6238:CBG_04067
uniprot id: Q6E3D5
names: Function
messages: Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs.

6238:CBG 00038
gene id: 6238:CBG_00038
uniprot id: A8WM68
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 13093
gene id: 6238:CBG_13093
uniprot id: A8XH26
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 21867
gene id: 6238:CBG_21867
uniprot id: A8Y107
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

6238:CBG 00631
gene id: 6238:CBG_00631
uniprot id: A8WNE8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

6238:CBG 12070
gene id: 6238:CBG_12070
uniprot id: A8XEH5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

6238:CBG 17087
gene id: 6238:CBG_17087
uniprot id: A8XQE9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

6238:CBG 18602
gene id: 6238:CBG_18602
uniprot id: A8XTP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

6238:CBG 02161
gene id: 6238:CBG_02161
uniprot id: A8WS32
names: Similarity
messages: Belongs to the actin family.

6238:CBG 20733
gene id: 6238:CBG_20733
uniprot id: A8XYH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 23417
gene id: 6238:CBG_23417
uniprot id: A8Y3Z0
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 13457
gene id: 6238:CBG_13457
uniprot id: A8XHQ2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 17261
gene id: 6238:CBG_17261
uniprot id: A8XQG8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 05570
gene id: 6238:CBG_05570
uniprot id: A8X062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

6238:CBG 19328
gene id: 6238:CBG_19328
uniprot id: A8XVD3
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 17371
gene id: 6238:CBG_17371
uniprot id: A8XQX4
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

6238:CBG 11192
gene id: 6238:CBG_11192
uniprot id: A8XCN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 15628
gene id: 6238:CBG_15628
uniprot id: A8XME9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

6238:CBG 16479
gene id: 6238:CBG_16479
uniprot id: A8XP55
names: Similarity
messages: Belongs to the bystin family.

6238:CBG 05166
gene id: 6238:CBG_05166
uniprot id: A8WZA2
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

6238:CBG 24755
gene id: 6238:CBG_24755
uniprot id: G2J682
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 24279
gene id: 6238:CBG_24279
uniprot id: A8WKD2
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

6238:CBG 15726
gene id: 6238:CBG_15726
uniprot id: A8XMM5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 22170
gene id: 6238:CBG_22170
uniprot id: A8Y1Q2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

6238:CBG 10043
gene id: 6238:CBG_10043
uniprot id: A8XA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

6238:CBG 16478
gene id: 6238:CBG_16478
uniprot id: A8XP54
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

6238:CBG 23903
gene id: 6238:CBG_23903
uniprot id: A8WJJ6
names: Similarity
messages: Belongs to the amidase family.

6238:CBG 02788
gene id: 6238:CBG_02788
uniprot id: A8WTI3
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 06231
gene id: 6238:CBG_06231
uniprot id: A8X0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

6238:CBG 11197
gene id: 6238:CBG_11197
uniprot id: A8XCP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Required for normal brood size. May be involved in regulating mpk-1 phosphorylation downstream of phosphatase ptp-2 during oocyte maturation.
messages: Homodimer.

6238:CBG 19129
gene id: 6238:CBG_19129
uniprot id: A8XUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 21703
gene id: 6238:CBG_21703
uniprot id: A8Y0P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

6238:CBG 13539
gene id: 6238:CBG_13539
uniprot id: A8XI49
names: Subcellular Location Annotation
messages: Cytoplasm

6238:CBG 13974
gene id: 6238:CBG_13974
uniprot id: A8XIX1
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.

6238:CBG 17827
gene id: 6238:CBG_17827
uniprot id: A8XRV3
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 12918
gene id: 6238:CBG_12918
uniprot id: A8XGN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 10211
gene id: 6238:CBG_10211
uniprot id: A8XAU7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

6238:CBG 07125
gene id: 6238:CBG_07125
uniprot id: A8X3N0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

6238:CBG 03017
gene id: 6238:CBG_03017
uniprot id: A8WSZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: nuclear pore complex

6238:CBG 15226
gene id: 6238:CBG_15226
uniprot id: A8XLM4
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 03027
gene id: 6238:CBG_03027
uniprot id: A8WSY8
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 14399
gene id: 6238:CBG_14399
uniprot id: A8XJX2
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13328
gene id: 6238:CBG_13328
uniprot id: A8XHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

6238:CBG 19886
gene id: 6238:CBG_19886
uniprot id: A8XWN4
names: Similarity
messages: Belongs to the beclin family.

6238:CBG 04190
gene id: 6238:CBG_04190
uniprot id: A8WWD7
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 19995
gene id: 6238:CBG_19995
uniprot id: A8XWW4
names: Function
names: Similarity
names: Subunit
messages: Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulates Raf activity at specialized signaling complexes upon Ras activation. Required for vulval development. Involved in fluid homeostasis. Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine.
messages: Belongs to the SHOC2 family.
messages: Interacts with let-60.

6238:CBG 24374
gene id: 6238:CBG_24374
uniprot id: A8WKK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

6238:CBG 23121
gene id: 6238:CBG_23121
uniprot id: A8Y4N2
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 19391
gene id: 6238:CBG_19391
uniprot id: A8XVI6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05436
gene id: 6238:CBG_05436
uniprot id: A8WZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

6238:CBG 07150
gene id: 6238:CBG_07150
uniprot id: A8X3L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 18258
gene id: 6238:CBG_18258
uniprot id: A8XS97
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 03818
gene id: 6238:CBG_03818
uniprot id: A8WWT8
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 06916
gene id: 6238:CBG_06916
uniprot id: A8X3C9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

6238:CBG 23127
gene id: 6238:CBG_23127
uniprot id: Q60MJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family. G(q) subfamily.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 20477
gene id: 6238:CBG_20477
uniprot id: A8XXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

6238:CBG 09769
gene id: 6238:CBG_09769
uniprot id: A8X9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

6238:CBG 21665
gene id: 6238:CBG_21665
uniprot id: A8Y0T1
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 23101
gene id: 6238:CBG_23101
uniprot id: A8Y4P9
names: Similarity
messages: Belongs to the peptidase S33 family.

6238:CBG 21007
gene id: 6238:CBG_21007
uniprot id: A8XZ56
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 20993
gene id: 6238:CBG_20993
uniprot id: A8XZ46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 14781
gene id: 6238:CBG_14781
uniprot id: A8XKN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 05834
gene id: 6238:CBG_05834
uniprot id: A8X1I8
names: Similarity
messages: Belongs to the actin family.

6238:CBG 19204
gene id: 6238:CBG_19204
uniprot id: A8XV27
names: Similarity
messages: Belongs to the histone H3 family.

6238:CBG 02890
gene id: 6238:CBG_02890
uniprot id: A8WTA0
names: Similarity
messages: Belongs to the splicing factor SR family.

6238:CBG 12888
gene id: 6238:CBG_12888
uniprot id: A8XFU0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

6238:CBG 05816
gene id: 6238:CBG_05816
uniprot id: A8X1K2
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

6238:CBG 06072
gene id: 6238:CBG_06072
uniprot id: A8X0Z0
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
messages: Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.

6238:CBG 06905
gene id: 6238:CBG_06905
uniprot id: A8X3B9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 08493
gene id: 6238:CBG_08493
uniprot id: A8X6P7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

6238:CBG 10811
gene id: 6238:CBG_10811
uniprot id: A8XBU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

6238:CBG 23205
gene id: 6238:CBG_23205
uniprot id: A8Y4G6
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 03966
gene id: 6238:CBG_03966
uniprot id: A8WVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 05838
gene id: 6238:CBG_05838
uniprot id: G2J6F9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 22511
gene id: 6238:CBG_22511
uniprot id: A8Y2F8
names: Subcellular Location Annotation
messages: Mitochondrion

6238:CBG 23482
gene id: 6238:CBG_23482
uniprot id: A8Y3T5
names: Similarity
messages: Belongs to the FAX family.

6238:CBG 09879
gene id: 6238:CBG_09879
uniprot id: Q61J97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Nucleus
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating splicing of S-adenosylmethionine synthase transcripts (sams-3, sams-4 and sams-5). Able to N6-methylate a subset of mRNAs containing the 5'UACAGAAAC-3' nonamer sequence. Plays a key role in S-adenosyl-L-methionine homeostasis: under rich-diet conditions, catalyzes N6-methylation of S-adenosylmethionine synthase mRNAs (sams-3, sams-4 and sams-5), directly inhibiting splicing and protein production of S-adenosylmethionine synthase. In addition to mRNAs, also able to mediate N6-methylation of U6 small nuclear RNA (U6 snRNA). Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo.
messages: Self-associates. Interacts with dlc-1; the interaction is direct, and is required for nuclear localization of mett-10.

6238:CBG 23745
gene id: 6238:CBG_23745
uniprot id: A8WJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

6238:CBG 01651
gene id: 6238:CBG_01651
uniprot id: A8WR60
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

6238:CBG 12362
gene id: 6238:CBG_12362
uniprot id: A8XF90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

6238:CBG 22152
gene id: 6238:CBG_22152
uniprot id: A8Y1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with atg-12.
messages: Involved in autophagic vesicle formation.
messages: Preautophagosomal structure membrane

6238:CBG 04078
gene id: 6238:CBG_04078
uniprot id: A8WW58
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

6238:CBG 14833
gene id: 6238:CBG_14833
uniprot id: A8XKT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

6238:CBG 08623
gene id: 6238:CBG_08623
uniprot id: A8X6Y8
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 01356
gene id: 6238:CBG_01356
uniprot id: A8WQ81
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 02247
gene id: 6238:CBG_02247
uniprot id: A8WS68
names: Similarity
messages: Belongs to the NDK family.

6238:CBG 09671
gene id: 6238:CBG_09671
uniprot id: A8X8I3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12193
gene id: 6238:CBG_12193
uniprot id: A8XF10
names: Similarity
messages: Belongs to the dynein heavy chain family.

6238:CBG 09153
gene id: 6238:CBG_09153
uniprot id: A8X872
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

6238:CBG 01199
gene id: 6238:CBG_01199
uniprot id: A8WPT8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 16247
gene id: 6238:CBG_16247
uniprot id: A8XNT7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

6238:CBG 02934
gene id: 6238:CBG_02934
uniprot id: Q61ZW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIMR family.
messages: Cell membrane
messages: May associate with G-protein coupled receptors and regulate downstream signaling pathways.

6238:CBG 21019
gene id: 6238:CBG_21019
uniprot id: A8XZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

6238:CBG 03992
gene id: 6238:CBG_03992
uniprot id: A8WVX9
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 22322
gene id: 6238:CBG_22322
uniprot id: A8Y226
names: Similarity
messages: Belongs to the actin family.

6238:CBG 02936
gene id: 6238:CBG_02936
uniprot id: A8WT63
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22497
gene id: 6238:CBG_22497
uniprot id: A8Y2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

6238:CBG 21033
gene id: 6238:CBG_21033
uniprot id: A8XZ79
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 09436
gene id: 6238:CBG_09436
uniprot id: A8X939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

6238:CBG 15783
gene id: 6238:CBG_15783
uniprot id: A8XMS9
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 16850
gene id: 6238:CBG_16850
uniprot id: A8XPY1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 07989
gene id: 6238:CBG_07989
uniprot id: Q5WNI9
names: Function
names: Similarity
messages: Belongs to the dopey family.
messages: Essential for cell patterning during gastrulation. May be involved in protein traffic between late Golgi and early endosomes (By similarity).

6238:CBG 05672
gene id: 6238:CBG_05672
uniprot id: A8X0E7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03798
gene id: 6238:CBG_03798
uniprot id: Q61XX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family.
messages: Executes the initial step of microRNA (miRNA) processing in the nucleus, that is the cleavage of pri-miRNA to release pre-miRNA. Involved in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in fertility. Required for the function or synthesis of the let-7 miRNA (By similarity).
messages: Nucleus

6238:CBG 24500
gene id: 6238:CBG_24500
uniprot id: A8WKU8
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 02557
gene id: 6238:CBG_02557
uniprot id: A8WU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 12442
gene id: 6238:CBG_12442
uniprot id: A8XFG0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01011
gene id: 6238:CBG_01011
uniprot id: A8WP42
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 09432
gene id: 6238:CBG_09432
uniprot id: A8X943
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 09573
gene id: 6238:CBG_09573
uniprot id: A8X8S4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

6238:CBG 06055
gene id: 6238:CBG_06055
uniprot id: G2J6F9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 06233
gene id: 6238:CBG_06233
uniprot id: A8X0K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

6238:CBG 07090
gene id: 6238:CBG_07090
uniprot id: A8X3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Vesicle

6238:CBG 08279
gene id: 6238:CBG_08279
uniprot id: E3CU02
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

6238:CBG 14907
gene id: 6238:CBG_14907
uniprot id: A8XKY8
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

6238:CBG 07436
gene id: 6238:CBG_07436
uniprot id: A8X4S0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 02941
gene id: 6238:CBG_02941
uniprot id: A8WT59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 10878
gene id: 6238:CBG_10878
uniprot id: A8XC71
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

6238:CBG 16997
gene id: 6238:CBG_16997
uniprot id: A8XQ82
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 10817
gene id: 6238:CBG_10817
uniprot id: G2J745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 11507
gene id: 6238:CBG_11507
uniprot id: A8XCU3
names: Similarity
messages: Belongs to the CCZ1 family.

6238:CBG 18244
gene id: 6238:CBG_18244
uniprot id: A8XS84
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 23058
gene id: 6238:CBG_23058
uniprot id: A8Y4T3
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 01586
gene id: 6238:CBG_01586
uniprot id: A8WRB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

6238:CBG 09248
gene id: 6238:CBG_09248
uniprot id: A8X9J1
names: Similarity
messages: Belongs to the CWF19 family.

6238:CBG 07059
gene id: 6238:CBG_07059
uniprot id: A8X3T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

6238:CBG 05292
gene id: 6238:CBG_05292
uniprot id: A8WZJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

6238:CBG 03725
gene id: 6238:CBG_03725
uniprot id: A8WWK0
names: Similarity
messages: Belongs to the dUTPase family.

6238:CBG 20944
gene id: 6238:CBG_20944
uniprot id: E3CU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 18052
gene id: 6238:CBG_18052
uniprot id: A8XSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

6238:CBG 20816
gene id: 6238:CBG_20816
uniprot id: A8XYP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15185
gene id: 6238:CBG_15185
uniprot id: Q616Q2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of ddp-1/tim-8 and 3 copies of tin-13/tim-13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of tim-22 (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The ddp-1/tim-8-tim-13 complex mediates the import of some proteins while the predominant tim-9/tin-9.1-tim-10/tin-10 70 kDa complex mediates the import of much more proteins.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of ddp-1/tim-8 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane.

6238:CBG 09496
gene id: 6238:CBG_09496
uniprot id: A8X8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

6238:CBG 14491
gene id: 6238:CBG_14491
uniprot id: A8XK18
names: Similarity
messages: Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.

6238:CBG 05149
gene id: 6238:CBG_05149
uniprot id: A8WZ58
names: Similarity
messages: Belongs to the cytidylyltransferase family.

6238:CBG 01550
gene id: 6238:CBG_01550
uniprot id: A8WRE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

6238:CBG 20957
gene id: 6238:CBG_20957
uniprot id: A8XZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 01211
gene id: 6238:CBG_01211
uniprot id: A8WPU7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23731
gene id: 6238:CBG_23731
uniprot id: A8WJ59
names: Similarity
messages: Belongs to the acetyltransferase family. NAA60 subfamily.

6238:CBG 12656
gene id: 6238:CBG_12656
uniprot id: A8XG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

6238:CBG 15936
gene id: 6238:CBG_15936
uniprot id: A8XNF8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 06761
gene id: 6238:CBG_06761
uniprot id: A8X308
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 18693
gene id: 6238:CBG_18693
uniprot id: A8XTW3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

6238:CBG 19978
gene id: 6238:CBG_19978
uniprot id: A8XWV1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

6238:CBG 10288
gene id: 6238:CBG_10288
uniprot id: A8XAP1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 23348
gene id: 6238:CBG_23348
uniprot id: A8Y449
names: Similarity
messages: Belongs to the cyclin family.

6238:CBG 03917
gene id: 6238:CBG_03917
uniprot id: A8WVR2
names: Function
names: Similarity
messages: Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif (By similarity).
messages: Belongs to the methyltransferase superfamily. NTM1 family.

6238:CBG 06199
gene id: 6238:CBG_06199
uniprot id: A8X0P1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

6238:CBG 08425
gene id: 6238:CBG_08425
uniprot id: A8X6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Required for correct subcellular localization of pgl-1 (By similarity).

6238:CBG 14916
gene id: 6238:CBG_14916
uniprot id: A8XKZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

6238:CBG 07047
gene id: 6238:CBG_07047
uniprot id: A8X3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
messages: Secreted

6238:CBG 23508
gene id: 6238:CBG_23508
uniprot id: A8Y3R5
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

6238:CBG 22870
gene id: 6238:CBG_22870
uniprot id: A8Y393
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20956
gene id: 6238:CBG_20956
uniprot id: A8XZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 20988
gene id: 6238:CBG_20988
uniprot id: A8XZ41
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 15025
gene id: 6238:CBG_15025
uniprot id: A8XL82
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 04877
gene id: 6238:CBG_04877
uniprot id: A8WYP7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 15714
gene id: 6238:CBG_15714
uniprot id: A8XML4
names: Similarity
messages: Belongs to the TACO1 family.

6238:CBG 13478
gene id: 6238:CBG_13478
uniprot id: A8XHN4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02487
gene id: 6238:CBG_02487
uniprot id: A8WU74
names: Similarity
messages: Belongs to the MT-A70-like family.

6238:CBG 15881
gene id: 6238:CBG_15881
uniprot id: A8XMZ8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 14894
gene id: 6238:CBG_14894
uniprot id: A8XKX5
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12444
gene id: 6238:CBG_12444
uniprot id: A8XFG1
names: Similarity
messages: Belongs to the PIAS family.

6238:CBG 20666
gene id: 6238:CBG_20666
uniprot id: A8XYB6
names: Similarity
messages: Belongs to the DEAD box helicase family.

6238:CBG 16619
gene id: 6238:CBG_16619
uniprot id: A8XPL6
names: Subcellular Location Annotation
messages: Cytoplasm

6238:CBG 01747
gene id: 6238:CBG_01747
uniprot id: A8WQY0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 04176
gene id: 6238:CBG_04176
uniprot id: A8WWC5
names: Similarity
messages: Belongs to the DCC1 family.

6238:CBG 22235
gene id: 6238:CBG_22235
uniprot id: A8Y1U9
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

6238:CBG 19676
gene id: 6238:CBG_19676
uniprot id: A8XW61
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

6238:CBG 09491
gene id: 6238:CBG_09491
uniprot id: A8X8Z9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

6238:CBG 22855
gene id: 6238:CBG_22855
uniprot id: A8Y379
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
messages: Membrane
messages: Microsome membrane

6238:CBG 09724
gene id: 6238:CBG_09724
uniprot id: A8X8E9
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 09259
gene id: 6238:CBG_09259
uniprot id: A8X9I3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 20759
gene id: 6238:CBG_20759
uniprot id: A8XYJ6
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

6238:CBG 13574
gene id: 6238:CBG_13574
uniprot id: A8XI78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 04630
gene id: 6238:CBG_04630
uniprot id: A8WY38
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 20702
gene id: 6238:CBG_20702
uniprot id: E3CU79
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 23930
gene id: 6238:CBG_23930
uniprot id: A8WJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

6238:CBG 21580
gene id: 6238:CBG_21580
uniprot id: A8Y0F3
names: Similarity
messages: Belongs to the peptidase C2 family.

6238:CBG 10449
gene id: 6238:CBG_10449
uniprot id: A8XB88
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

6238:CBG 03391
gene id: 6238:CBG_03391
uniprot id: A8WUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

6238:CBG 21024
gene id: 6238:CBG_21024
uniprot id: A8XZ71
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

6238:CBG 13858
gene id: 6238:CBG_13858
uniprot id: A8XIV5
names: Similarity
messages: Belongs to the EPS8 family.

6238:CBG 08166
gene id: 6238:CBG_08166
uniprot id: A8X5Z0
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 04192
gene id: 6238:CBG_04192
uniprot id: A8WWD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

6238:CBG 01948
gene id: 6238:CBG_01948
uniprot id: A8WRN2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18323
gene id: 6238:CBG_18323
uniprot id: A8XSF5
names: Similarity
messages: Belongs to the PP2C family.

6238:CBG 18326
gene id: 6238:CBG_18326
uniprot id: A8XSF8
names: Similarity
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.

6238:CBG 19031
gene id: 6238:CBG_19031
uniprot id: A8XUL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 01524
gene id: 6238:CBG_01524
uniprot id: A0T3A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

6238:CBG 23507
gene id: 6238:CBG_23507
uniprot id: A8Y3R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 22646
gene id: 6238:CBG_22646
uniprot id: A8Y2R9
names: Similarity
messages: Belongs to the CWC15 family.

6238:CBG 02376
gene id: 6238:CBG_02376
uniprot id: A8WUH1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

6238:CBG 07608
gene id: 6238:CBG_07608
uniprot id: A8X4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

6238:CBG 23125
gene id: 6238:CBG_23125
uniprot id: A8Y4M9
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 12292
gene id: 6238:CBG_12292
uniprot id: G2J6R2
names: Similarity
messages: Belongs to the GST superfamily. Omega family.

6238:CBG 07378
gene id: 6238:CBG_07378
uniprot id: A8X4W7
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

6238:CBG 10962
gene id: 6238:CBG_10962
uniprot id: A8XBY4
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

6238:CBG 21313
gene id: 6238:CBG_21313
uniprot id: A8XZT5
names: Similarity
messages: Belongs to the RRM RBM42 family.

6238:CBG 18548
gene id: 6238:CBG_18548
uniprot id: Q60XS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle.

6238:CBG 10862
gene id: 6238:CBG_10862
uniprot id: A8XC58
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19366
gene id: 6238:CBG_19366
uniprot id: A8XVG3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 02222
gene id: 6238:CBG_02222
uniprot id: A8WS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

6238:CBG 02729
gene id: 6238:CBG_02729
uniprot id: A8WTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOC2 family.
messages: Nucleus
messages: Required for normal somatic gonad development and for regulation of germline development and proliferation.

6238:CBG 02448
gene id: 6238:CBG_02448
uniprot id: A8WUA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

6238:CBG 05037
gene id: 6238:CBG_05037
uniprot id: A8WZ13
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 10351
gene id: 6238:CBG_10351
uniprot id: A8XB06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15050
gene id: 6238:CBG_15050
uniprot id: A8XLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 10414
gene id: 6238:CBG_10414
uniprot id: A8XB55
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 16760
gene id: 6238:CBG_16760
uniprot id: A8XPR8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

6238:CBG 20818
gene id: 6238:CBG_20818
uniprot id: A8XYP5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 16943
gene id: 6238:CBG_16943
uniprot id: A8XQ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

6238:CBG 11394
gene id: 6238:CBG_11394
uniprot id: A8XD45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: nucleolus

6238:CBG 19904
gene id: 6238:CBG_19904
uniprot id: A8XWP9
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 04988
gene id: 6238:CBG_04988
uniprot id: A8WYX7
names: Similarity
messages: Belongs to the peptidase M13 family.

6238:CBG 13068
gene id: 6238:CBG_13068
uniprot id: A8XH03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

6238:CBG 22042
gene id: 6238:CBG_22042
uniprot id: A8Y1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

6238:CBG 06010
gene id: 6238:CBG_06010
uniprot id: A8X142
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

6238:CBG 10118
gene id: 6238:CBG_10118
uniprot id: A8XAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 08436
gene id: 6238:CBG_08436
uniprot id: A8X6J7
names: Similarity
messages: Belongs to the Mo25 family.

6238:CBG 21327
gene id: 6238:CBG_21327
uniprot id: A8XZU8
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

6238:CBG 17996
gene id: 6238:CBG_17996
uniprot id: A8XSS3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

6238:CBG 21169
gene id: 6238:CBG_21169
uniprot id: A8XZC2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Belongs to the pex2/pex10/pex12 family.

6238:CBG 11904
gene id: 6238:CBG_11904
uniprot id: Q4VT27
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

6238:CBG 01780
gene id: 6238:CBG_01780
uniprot id: A8WQU8
names: Similarity
messages: Belongs to the phosducin family.

6238:CBG 12149
gene id: 6238:CBG_12149
uniprot id: A8XEV3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

6238:CBG 12520
gene id: 6238:CBG_12520
uniprot id: Q61DE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

6238:CBG 22542
gene id: 6238:CBG_22542
uniprot id: A8Y2I5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 10952
gene id: 6238:CBG_10952
uniprot id: A8XBX8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 02104
gene id: 6238:CBG_02104
uniprot id: A8WRZ9
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

6238:CBG 11074
gene id: 6238:CBG_11074
uniprot id: A8XCC6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

6238:CBG 09979
gene id: 6238:CBG_09979
uniprot id: A8XA31
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

6238:CBG 06021
gene id: 6238:CBG_06021
uniprot id: Q61SU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Has a role in gonadogenesis (By similarity).
messages: Cytoplasm
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

6238:CBG 00501
gene id: 6238:CBG_00501
uniprot id: A8WMT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

6238:CBG 20995
gene id: 6238:CBG_20995
uniprot id: G2J697
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 12389
gene id: 6238:CBG_12389
uniprot id: A8XFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

6238:CBG 10415
gene id: 6238:CBG_10415
uniprot id: A8XB56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 14829
gene id: 6238:CBG_14829
uniprot id: P19208
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: AMPylated by fic-1.
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

6238:CBG 03132
gene id: 6238:CBG_03132
uniprot id: A8WSQ5
names: Similarity
messages: Belongs to the peptidase S10 family.

6238:CBG 08820
gene id: 6238:CBG_08820
uniprot id: A8X7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

6238:CBG 17010
gene id: 6238:CBG_17010
uniprot id: A8XQ93
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 07302
gene id: 6238:CBG_07302
uniprot id: A8X521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

6238:CBG 03909
gene id: 6238:CBG_03909
uniprot id: A8WVQ5
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

6238:CBG 18047
gene id: 6238:CBG_18047
uniprot id: A8XSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 08278
gene id: 6238:CBG_08278
uniprot id: A8X672
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09535
gene id: 6238:CBG_09535
uniprot id: A8X8V6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 20620
gene id: 6238:CBG_20620
uniprot id: A8XY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 03307
gene id: 6238:CBG_03307
uniprot id: A8WSC0
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

6238:CBG 07163
gene id: 6238:CBG_07163
uniprot id: A8X3K5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 23008
gene id: 6238:CBG_23008
uniprot id: A8Y3G4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

6238:CBG 17341
gene id: 6238:CBG_17341
uniprot id: A8XQV0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22911
gene id: 6238:CBG_22911
uniprot id: A8Y3C5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 20703
gene id: 6238:CBG_20703
uniprot id: A8XYF1
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 19741
gene id: 6238:CBG_19741
uniprot id: A8XWF3
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

6238:CBG 19242
gene id: 6238:CBG_19242
uniprot id: A8XV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 22023
gene id: 6238:CBG_22023
uniprot id: A8Y1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

6238:CBG 15296
gene id: 6238:CBG_15296
uniprot id: A8XLV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane

6238:CBG 15477
gene id: 6238:CBG_15477
uniprot id: A8XM79
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 16374
gene id: 6238:CBG_16374
uniprot id: Q27459
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Oligomer composed of disulfide-linked homodimers.
messages: Rapidly hydrolyzes choline released into the synapse.
messages: Secreted
messages: Synapse

6238:CBG 03392
gene id: 6238:CBG_03392
uniprot id: A8WUY2
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

6238:CBG 03711
gene id: 6238:CBG_03711
uniprot id: A8WWI7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12120
gene id: 6238:CBG_12120
uniprot id: A8XES9
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 01556
gene id: 6238:CBG_01556
uniprot id: A8WRD6
names: Similarity
messages: Belongs to the amidase family.

6238:CBG 18056
gene id: 6238:CBG_18056
uniprot id: A8XSX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm

6238:CBG 09046
gene id: 6238:CBG_09046
uniprot id: A8X7X9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety (By similarity). Involved in regulation of protein homeostasis, longevity and reproducive life span. Specifically regulates proteotoxicity due to age-related aggregation of proteins like alpha-synuclein, via its effects on tryptophan metabolism (By similarity).
messages: Homotetramer. Dimer of dimers.

6238:CBG 21465
gene id: 6238:CBG_21465
uniprot id: A8Y039
names: Similarity
messages: Belongs to the peptidase M14 family.

6238:CBG 00262
gene id: 6238:CBG_00262
uniprot id: A8WMK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03000
gene id: 6238:CBG_03000
uniprot id: A8WT11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

6238:CBG 21917
gene id: 6238:CBG_21917
uniprot id: Q60Q90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site (By similarity).

6238:CBG 01097
gene id: 6238:CBG_01097
uniprot id: A8WPJ8
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

6238:CBG 19213
gene id: 6238:CBG_19213
uniprot id: A8XV34
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03202
gene id: 6238:CBG_03202
uniprot id: A8WSK1
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

6238:CBG 04617
gene id: 6238:CBG_04617
uniprot id: A8WY26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: nucleolus

6238:CBG 11728
gene id: 6238:CBG_11728
uniprot id: A8XDV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS).
messages: Monomer.

6238:CBG 12550
gene id: 6238:CBG_12550
uniprot id: A8XG07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

6238:CBG 22500
gene id: 6238:CBG_22500
uniprot id: A8Y2E9
names: Similarity
messages: Belongs to the ATPase gamma chain family.

6238:CBG 23345
gene id: 6238:CBG_23345
uniprot id: A8Y452
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

6238:CBG 20928
gene id: 6238:CBG_20928
uniprot id: A8XYZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

6238:CBG 09267
gene id: 6238:CBG_09267
uniprot id: A8X9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 16597
gene id: 6238:CBG_16597
uniprot id: A8XPJ7
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

6238:CBG 23370
gene id: 6238:CBG_23370
uniprot id: A8Y430
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 19394
gene id: 6238:CBG_19394
uniprot id: A8XVI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 05353
gene id: 6238:CBG_05353
uniprot id: A8WZN5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 18921
gene id: 6238:CBG_18921
uniprot id: A8XUC8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

6238:CBG 12121
gene id: 6238:CBG_12121
uniprot id: A8XET0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 04030
gene id: 6238:CBG_04030
uniprot id: Q61XD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Chromosome
messages: Interacts with zen-4 and icp-1. Part of a complex containing at least air-2; icp-1; csc-1 and bir-1. Interacts with tlk-1 and bmk-1 (By similarity).
messages: Midbody
messages: Serine/threonine-protein kinase which mediates both meiotic and mitotic chromosome segregation. Required for histone H3 'Ser-10' phosphorylation. Phosphorylates tlk-1 and zen-4 (By similarity).
messages: cytoskeleton

6238:CBG 23215
gene id: 6238:CBG_23215
uniprot id: A8Y4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

6238:CBG 12385
gene id: 6238:CBG_12385
uniprot id: Q95WA6
names: Similarity
messages: Belongs to the BTG family.

6238:CBG 03450
gene id: 6238:CBG_03450
uniprot id: A8WV34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 12350
gene id: 6238:CBG_12350
uniprot id: A8XFM5
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

6238:CBG 16602
gene id: 6238:CBG_16602
uniprot id: A8XPK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

6238:CBG 01860
gene id: 6238:CBG_01860
uniprot id: A8WRG2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 19269
gene id: 6238:CBG_19269
uniprot id: A8XV82
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

6238:CBG 16194
gene id: 6238:CBG_16194
uniprot id: A8XNX0
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

6238:CBG 09613
gene id: 6238:CBG_09613
uniprot id: A8X8N5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 01666
gene id: 6238:CBG_01666
uniprot id: A8WR46
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

6238:CBG 12345
gene id: 6238:CBG_12345
uniprot id: A8XFM0
names: Similarity
messages: Belongs to the TBP family.

6238:CBG 19766
gene id: 6238:CBG_19766
uniprot id: A8XWD2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 08324
gene id: 6238:CBG_08324
uniprot id: A8X6A9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 06809
gene id: 6238:CBG_06809
uniprot id: Q9GPN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

6238:CBG 17275
gene id: 6238:CBG_17275
uniprot id: A8XQR1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 04120
gene id: 6238:CBG_04120
uniprot id: A8WW92
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

6238:CBG 19687
gene id: 6238:CBG_19687
uniprot id: A8XW72
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

6238:CBG 16491
gene id: 6238:CBG_16491
uniprot id: G2J6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

6238:CBG 04016
gene id: 6238:CBG_04016
uniprot id: A8WVZ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 14224
gene id: 6238:CBG_14224
uniprot id: A8XJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

6238:CBG 16407
gene id: 6238:CBG_16407
uniprot id: A8XNI3
names: Similarity
messages: Belongs to the peptidase M14 family.

6238:CBG 05155
gene id: 6238:CBG_05155
uniprot id: A8WZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

6238:CBG 19879
gene id: 6238:CBG_19879
uniprot id: A8XWM9
names: Similarity
messages: Belongs to the glutamine synthetase family.

6238:CBG 13600
gene id: 6238:CBG_13600
uniprot id: A8XIA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

6238:CBG 15311
gene id: 6238:CBG_15311
uniprot id: A8XLW9
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

6238:CBG 13916
gene id: 6238:CBG_13916
uniprot id: A8XJ16
names: Similarity
messages: Belongs to the GDNFR family.

6238:CBG 08480
gene id: 6238:CBG_08480
uniprot id: A8X6N5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 11572
gene id: 6238:CBG_11572
uniprot id: A8XDI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

6238:CBG 17326
gene id: 6238:CBG_17326
uniprot id: Q9GNL2
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cleaved by caspase ced-3 in vitro.
messages: Heterochronic protein which controls the choice of stage specific cell fates. Involved in the temporal progression of vulval fate patterning, possibly by inhibiting lin-12. Acts as a transcription factor involved in the stage-specific repression of insulin/insulin-like growth factor gene ins-33.
messages: Nucleus

6238:CBG 10905
gene id: 6238:CBG_10905
uniprot id: A8XC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane

6238:CBG 12642
gene id: 6238:CBG_12642
uniprot id: Q61D43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 19058
gene id: 6238:CBG_19058
uniprot id: A8XUP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 09729
gene id: 6238:CBG_09729
uniprot id: A8X8E5
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Belongs to the PIH1 family.

6238:CBG 12664
gene id: 6238:CBG_12664
uniprot id: A8XGA3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

6238:CBG 22337
gene id: 6238:CBG_22337
uniprot id: A8Y265
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05989
gene id: 6238:CBG_05989
uniprot id: A8X162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Membrane

6238:CBG 08856
gene id: 6238:CBG_08856
uniprot id: A8X7J9
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23734
gene id: 6238:CBG_23734
uniprot id: A8WJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

6238:CBG 01332
gene id: 6238:CBG_01332
uniprot id: A8WQ58
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 03799
gene id: 6238:CBG_03799
uniprot id: A8WWR8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

6238:CBG 02905
gene id: 6238:CBG_02905
uniprot id: A8WT90
names: Similarity
messages: Belongs to the histone H3 family.

6238:CBG 03400
gene id: 6238:CBG_03400
uniprot id: A8WUY9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

6238:CBG 22015
gene id: 6238:CBG_22015
uniprot id: A8Y1C2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

6238:CBG 18243
gene id: 6238:CBG_18243
uniprot id: A8XS83
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 02629
gene id: 6238:CBG_02629
uniprot id: A8WTV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically di- and trimethylates 'Lys-20' of histone H4 (H4K20me2/me3). H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Contributes to dosage compensation of X chromosome-relative to autosome-linked gene expression, possibly by converting H4K20me1 to H4K20m2/me3 on autosomes. Involved in the regulation of growth and body fat metabolism downstream of the TOR complex 2 pathway.
messages: Nucleus

6238:CBG 03118
gene id: 6238:CBG_03118
uniprot id: A8WSR2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18143
gene id: 6238:CBG_18143
uniprot id: A8XT41
names: Similarity
messages: Belongs to the PITHD1 family.

6238:CBG 03319
gene id: 6238:CBG_03319
uniprot id: A8WUR9
names: Subcellular Location Annotation
messages: nucleolus

6238:CBG 13497
gene id: 6238:CBG_13497
uniprot id: A8XI11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

6238:CBG 18316
gene id: 6238:CBG_18316
uniprot id: Q60YA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pseudouridine synthase TruB family.
messages: Component of the small nucleolar ribonucleoprotein particle containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
messages: nucleolus

6238:CBG 03731
gene id: 6238:CBG_03731
uniprot id: A8WWK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 14716
gene id: 6238:CBG_14716
uniprot id: A8XKI5
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 23108
gene id: 6238:CBG_23108
uniprot id: A8Y4P2
names: Function
names: Similarity
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.

6238:CBG 04590
gene id: 6238:CBG_04590
uniprot id: A8WY03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

6238:CBG 18386
gene id: 6238:CBG_18386
uniprot id: A8XSL0
names: Similarity
messages: Belongs to the BACURD family.

6238:CBG 16281
gene id: 6238:CBG_16281
uniprot id: A8XNR4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

6238:CBG 13026
gene id: 6238:CBG_13026
uniprot id: O97472
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

6238:CBG 22319
gene id: 6238:CBG_22319
uniprot id: G2J679
names: Similarity
messages: Belongs to the MAPRE family.

6238:CBG 14198
gene id: 6238:CBG_14198
uniprot id: A8XJH8
names: Similarity
messages: Belongs to the apyrase family.

6238:CBG 13684
gene id: 6238:CBG_13684
uniprot id: A8XIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

6238:CBG 22088
gene id: 6238:CBG_22088
uniprot id: A8Y1H9
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 08416
gene id: 6238:CBG_08416
uniprot id: A8X6I2
names: Similarity
messages: Belongs to the DCP1 family.

6238:CBG 12401
gene id: 6238:CBG_12401
uniprot id: A8XFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane
messages: Microsome membrane

6238:CBG 20103
gene id: 6238:CBG_20103
uniprot id: A8XX36
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 13569
gene id: 6238:CBG_13569
uniprot id: A8XI75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Chromosome
messages: In the pre-SET domain, Cys residues bind 3 zinc ions that are arranged in a triangular cluster; some of these Cys residues contribute to the binding of two zinc ions within the cluster.
messages: Nucleus
messages: Probable histone methyltransferase required for embryonic development.

6238:CBG 08967
gene id: 6238:CBG_08967
uniprot id: A8X844
names: Similarity
messages: Belongs to the group II decarboxylase family.

6238:CBG 05401
gene id: 6238:CBG_05401
uniprot id: A8WZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

6238:CBG 08128
gene id: 6238:CBG_08128
uniprot id: A8X5V8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 23332
gene id: 6238:CBG_23332
uniprot id: A8Y461
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

6238:CBG 07897
gene id: 6238:CBG_07897
uniprot id: A8X5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 18807
gene id: 6238:CBG_18807
uniprot id: A8XU56
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.

6238:CBG 19532
gene id: 6238:CBG_19532
uniprot id: G2J700
names: Similarity
messages: Belongs to the BACURD family.

6238:CBG 09004
gene id: 6238:CBG_09004
uniprot id: Q61LA8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alternates between an inactive GDP-bound form and an active GTP-bound form (By similarity). Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by GTPase-activating protein (GAP) (By similarity).
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Golgi apparatus membrane
messages: Small GTPase involved in protein trafficking between different compartments. Modulates vesicle budding and uncoating within the Golgi complex. In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles (By similarity). Involved in endoplasmic reticulum dynamics during embryogenesis. Also required for adult germline function. Plays a role in cell shedding during embryogenesis probably by promoting the endocytosis of cell adhesion molecules. During neurogenesis, involved in cell autonomous Q.p neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell, probably by controlling endocytosis. Plays a role in maintaining mitochondrial morphology (By similarity).

6238:CBG 09991
gene id: 6238:CBG_09991
uniprot id: A8XA44
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

6238:CBG 06863
gene id: 6238:CBG_06863
uniprot id: A8X386
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

6238:CBG 12479
gene id: 6238:CBG_12479
uniprot id: A8XFV0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

6238:CBG 01898
gene id: 6238:CBG_01898
uniprot id: A8WRI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 00959
gene id: 6238:CBG_00959
uniprot id: A8WP85
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 23171
gene id: 6238:CBG_23171
uniprot id: A8Y4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

6238:CBG 06940
gene id: 6238:CBG_06940
uniprot id: A8X3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Golgi apparatus membrane

6238:CBG 03213
gene id: 6238:CBG_03213
uniprot id: A8WSJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

6238:CBG 14811
gene id: 6238:CBG_14811
uniprot id: G2J6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 05231
gene id: 6238:CBG_05231
uniprot id: A8WZF7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 20808
gene id: 6238:CBG_20808
uniprot id: A8XYN8
names: Similarity
messages: Belongs to the TTC38 family.

6238:CBG 19144
gene id: 6238:CBG_19144
uniprot id: A8XUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 06635
gene id: 6238:CBG_06635
uniprot id: A8X2Q3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 15266
gene id: 6238:CBG_15266
uniprot id: A8XLI8
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

6238:CBG 18231
gene id: 6238:CBG_18231
uniprot id: Q60YI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the small nucleolar ribonucleoprotein particle containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
messages: nucleolus

6238:CBG 09516
gene id: 6238:CBG_09516
uniprot id: A8X8X5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

6238:CBG 12095
gene id: 6238:CBG_12095
uniprot id: A8XEJ6
names: Similarity
messages: Belongs to the CAP family.

6238:CBG 02089
gene id: 6238:CBG_02089
uniprot id: A8WRY7
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01212
gene id: 6238:CBG_01212
uniprot id: A8WPU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 02374
gene id: 6238:CBG_02374
uniprot id: A8WUH2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

6238:CBG 10272
gene id: 6238:CBG_10272
uniprot id: A8XAQ5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 21964
gene id: 6238:CBG_21964
uniprot id: A8Y143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

6238:CBG 00962
gene id: 6238:CBG_00962
uniprot id: A8WP82
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.

6238:CBG 05782
gene id: 6238:CBG_05782
uniprot id: A8X1M9
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 17995
gene id: 6238:CBG_17995
uniprot id: A8XSS2
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 14749
gene id: 6238:CBG_14749
uniprot id: A8XKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

6238:CBG 23407
gene id: 6238:CBG_23407
uniprot id: A8Y3Z7
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 14771
gene id: 6238:CBG_14771
uniprot id: A8XKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 01700
gene id: 6238:CBG_01700
uniprot id: A8WR20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

6238:CBG 15353
gene id: 6238:CBG_15353
uniprot id: G2J6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

6238:CBG 10082
gene id: 6238:CBG_10082
uniprot id: A8XAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cytoplasm
messages: Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis. Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-2 and bre-4. Involved in resistance to the nematotoxic C.cinerea galectin Cgl2. Has a role in determining brood size (By similarity).

6238:CBG 09147
gene id: 6238:CBG_09147
uniprot id: A8X867
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 18401
gene id: 6238:CBG_18401
uniprot id: A8XT89
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

6238:CBG 00768
gene id: 6238:CBG_00768
uniprot id: A8WNS4
names: Similarity
messages: Belongs to the BROX family.

6238:CBG 19223
gene id: 6238:CBG_19223
uniprot id: A8XV43
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

6238:CBG 17903
gene id: 6238:CBG_17903
uniprot id: A8XS25
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20206
gene id: 6238:CBG_20206
uniprot id: A8XX71
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 22301
gene id: 6238:CBG_22301
uniprot id: G2J6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

6238:CBG 18055
gene id: 6238:CBG_18055
uniprot id: A8XSX7
names: Similarity
messages: Belongs to the insulin family.

6238:CBG 03682
gene id: 6238:CBG_03682
uniprot id: A8WVL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 16494
gene id: 6238:CBG_16494
uniprot id: A8XPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

6238:CBG 11199
gene id: 6238:CBG_11199
uniprot id: A8XCP5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 11100
gene id: 6238:CBG_11100
uniprot id: A8XCE6
names: Similarity
messages: Belongs to the TTC19 family.

6238:CBG 09554
gene id: 6238:CBG_09554
uniprot id: A8X8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 06096
gene id: 6238:CBG_06096
uniprot id: A8X0X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 09978
gene id: 6238:CBG_09978
uniprot id: A8XA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

6238:CBG 09216
gene id: 6238:CBG_09216
uniprot id: A8X8B7
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01045
gene id: 6238:CBG_01045
uniprot id: A8WP12
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 10310
gene id: 6238:CBG_10310
uniprot id: A8XAM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 11588
gene id: 6238:CBG_11588
uniprot id: A8XDK4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

6238:CBG 15672
gene id: 6238:CBG_15672
uniprot id: A8XMI2
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 05588
gene id: 6238:CBG_05588
uniprot id: A8X079
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

6238:CBG 14529
gene id: 6238:CBG_14529
uniprot id: A8XK47
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

6238:CBG 05962
gene id: 6238:CBG_05962
uniprot id: A8X182
names: Similarity
messages: Belongs to the ATG8 family.

6238:CBG 11120
gene id: 6238:CBG_11120
uniprot id: A8XCG2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

6238:CBG 21000
gene id: 6238:CBG_21000
uniprot id: Q60S81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping. Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity (By similarity).
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
messages: Cell membrane
messages: Neuronal AChR seems to be composed of two different type of subunits: alpha and beta.
messages: Postsynaptic cell membrane

6238:CBG 05839
gene id: 6238:CBG_05839
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 24603
gene id: 6238:CBG_24603
uniprot id: A8WL39
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 09893
gene id: 6238:CBG_09893
uniprot id: A8X9X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

6238:CBG 18893
gene id: 6238:CBG_18893
uniprot id: A8XUA9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

6238:CBG 18188
gene id: 6238:CBG_18188
uniprot id: A8XT80
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

6238:CBG 00309
gene id: 6238:CBG_00309
uniprot id: A8WMN9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

6238:CBG 15782
gene id: 6238:CBG_15782
uniprot id: A8XMS8
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19330
gene id: 6238:CBG_19330
uniprot id: A8XVD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
messages: Membrane
messages: Microsome membrane

6238:CBG 00649
gene id: 6238:CBG_00649
uniprot id: A8WND4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06259
gene id: 6238:CBG_06259
uniprot id: A8X0I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 18319
gene id: 6238:CBG_18319
uniprot id: A8XSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

6238:CBG 19691
gene id: 6238:CBG_19691
uniprot id: A8XW76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

6238:CBG 21209
gene id: 6238:CBG_21209
uniprot id: A8XZL4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

6238:CBG 01053
gene id: 6238:CBG_01053
uniprot id: Q626B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation. Required for embryonic development, germline proliferation and initiation of meiosis during spermatogenesis. Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (By similarity).
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Cytoplasm
messages: Golgi apparatus membrane

6238:CBG 09178
gene id: 6238:CBG_09178
uniprot id: A8X888
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 12542
gene id: 6238:CBG_12542
uniprot id: A8XG03
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 19062
gene id: 6238:CBG_19062
uniprot id: A8XUP5
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 01799
gene id: 6238:CBG_01799
uniprot id: A8WQT0
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

6238:CBG 08301
gene id: 6238:CBG_08301
uniprot id: A8X691
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

6238:CBG 06221
gene id: 6238:CBG_06221
uniprot id: A8X0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

6238:CBG 18607
gene id: 6238:CBG_18607
uniprot id: A8XTP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 03543
gene id: 6238:CBG_03543
uniprot id: A8WVA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

6238:CBG 20462
gene id: 6238:CBG_20462
uniprot id: A8XXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

6238:CBG 22549
gene id: 6238:CBG_22549
uniprot id: A8Y2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

6238:CBG 00931
gene id: 6238:CBG_00931
uniprot id: A8WPB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

6238:CBG 03709
gene id: 6238:CBG_03709
uniprot id: A8WWI5
names: Similarity
messages: Belongs to the nicastrin family.

6238:CBG 24679
gene id: 6238:CBG_24679
uniprot id: A8WL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

6238:CBG 04080
gene id: 6238:CBG_04080
uniprot id: A8WW60
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

6238:CBG 15211
gene id: 6238:CBG_15211
uniprot id: A8XLN6
names: Similarity
messages: Belongs to the DEF8 family.

6238:CBG 10001
gene id: 6238:CBG_10001
uniprot id: A8XA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane

6238:CBG 24535
gene id: 6238:CBG_24535
uniprot id: A8WKX5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 16683
gene id: 6238:CBG_16683
uniprot id: A8XPB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

6238:CBG 00458
gene id: 6238:CBG_00458
uniprot id: A8WN51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

6238:CBG 01521
gene id: 6238:CBG_01521
uniprot id: A8WQH7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

6238:CBG 03693
gene id: 6238:CBG_03693
uniprot id: A8WVL8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 10309
gene id: 6238:CBG_10309
uniprot id: A8XAM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 06101
gene id: 6238:CBG_06101
uniprot id: A8X0W6
names: Similarity
messages: Belongs to the complex I NDUFB6 subunit family.

6238:CBG 10777
gene id: 6238:CBG_10777
uniprot id: A8XBS2
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 07352
gene id: 6238:CBG_07352
uniprot id: A8X4Y6
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 03928
gene id: 6238:CBG_03928
uniprot id: A8WVS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

6238:CBG 01551
gene id: 6238:CBG_01551
uniprot id: A8WRE1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

6238:CBG 04521
gene id: 6238:CBG_04521
uniprot id: A8WXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

6238:CBG 23626
gene id: 6238:CBG_23626
uniprot id: A8WIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

6238:CBG 17113
gene id: 6238:CBG_17113
uniprot id: A8XQQ3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 03312
gene id: 6238:CBG_03312
uniprot id: A8WSB5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

6238:CBG 20102
gene id: 6238:CBG_20102
uniprot id: A8XX35
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 22739
gene id: 6238:CBG_22739
uniprot id: A8Y325
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 19329
gene id: 6238:CBG_19329
uniprot id: A8XVD4
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19889
gene id: 6238:CBG_19889
uniprot id: A8XWN7
names: Similarity
messages: Belongs to the peptidase M67A family. CSN5 subfamily.

6238:CBG 07923
gene id: 6238:CBG_07923
uniprot id: A8X5D5
names: Similarity
messages: Belongs to the WD repeat SMU1 family.

6238:CBG 13191
gene id: 6238:CBG_13191
uniprot id: A8XH94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

6238:CBG 03154
gene id: 6238:CBG_03154
uniprot id: A8WSN5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 19174
gene id: 6238:CBG_19174
uniprot id: A8XV02
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 01004
gene id: 6238:CBG_01004
uniprot id: Q626F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex which is a heterotetramer of gins1, gins2, gins3 and gins4.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

6238:CBG 21170
gene id: 6238:CBG_21170
uniprot id: A8XZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

6238:CBG 02198
gene id: 6238:CBG_02198
uniprot id: A8WSB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

6238:CBG 20732
gene id: 6238:CBG_20732
uniprot id: A8XYH1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 02637
gene id: 6238:CBG_02637
uniprot id: A8WTV1
names: Similarity
messages: Belongs to the Asterix family.

6238:CBG 00928
gene id: 6238:CBG_00928
uniprot id: A8WPA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

6238:CBG 09576
gene id: 6238:CBG_09576
uniprot id: A8X8S1
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 09461
gene id: 6238:CBG_09461
uniprot id: A8X920
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

6238:CBG 23401
gene id: 6238:CBG_23401
uniprot id: A8Y402
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 18863
gene id: 6238:CBG_18863
uniprot id: A8XU83
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.

6238:CBG 12849
gene id: 6238:CBG_12849
uniprot id: A8XFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

6238:CBG 11896
gene id: 6238:CBG_11896
uniprot id: A8XE93
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

6238:CBG 09354
gene id: 6238:CBG_09354
uniprot id: A8X9A5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 21260
gene id: 6238:CBG_21260
uniprot id: A8XZQ0
names: Similarity
messages: Belongs to the CWC16 family.

6238:CBG 21183
gene id: 6238:CBG_21183
uniprot id: A8XZN7
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

6238:CBG 15103
gene id: 6238:CBG_15103
uniprot id: A8Y210
names: Similarity
messages: Belongs to the peptidase M24B family.

6238:CBG 09443
gene id: 6238:CBG_09443
uniprot id: A8X933
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17727
gene id: 6238:CBG_17727
uniprot id: A8XRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

6238:CBG 06235
gene id: 6238:CBG_06235
uniprot id: A8X0K6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

6238:CBG 05258
gene id: 6238:CBG_05258
uniprot id: A8WZH3
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 20832
gene id: 6238:CBG_20832
uniprot id: A8XYQ9
names: Similarity
messages: Belongs to the SKI family.

6238:CBG 18062
gene id: 6238:CBG_18062
uniprot id: A8XSY1
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20586
gene id: 6238:CBG_20586
uniprot id: A8XY53
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

6238:CBG 11067
gene id: 6238:CBG_11067
uniprot id: A8XCB9
names: Subcellular Location Annotation
messages: cilium basal body

6238:CBG 22875
gene id: 6238:CBG_22875
uniprot id: A8Y397
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 12445
gene id: 6238:CBG_12445
uniprot id: A8XFG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Complex I is composed of 45 different subunits This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Mitochondrion

6238:CBG 14460
gene id: 6238:CBG_14460
uniprot id: A8XJZ8
names: Function
names: Similarity
messages: Belongs to the lst-2 family.
messages: Negative regulator of epidermal growth factor receptor (EGFR) signaling.

6238:CBG 12989
gene id: 6238:CBG_12989
uniprot id: A8XGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTF/NF-I family.
messages: Nucleus

6238:CBG 22920
gene id: 6238:CBG_22920
uniprot id: A8Y3N6
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17398
gene id: 6238:CBG_17398
uniprot id: A8XQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

6238:CBG 22551
gene id: 6238:CBG_22551
uniprot id: A8Y2J4
names: Similarity
messages: Belongs to the SPARC family.

6238:CBG 22443
gene id: 6238:CBG_22443
uniprot id: A8Y2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

6238:CBG 06108
gene id: 6238:CBG_06108
uniprot id: A8X0V9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

6238:CBG 14269
gene id: 6238:CBG_14269
uniprot id: A8XJM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 16310
gene id: 6238:CBG_16310
uniprot id: A8XNQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

6238:CBG 04313
gene id: 6238:CBG_04313
uniprot id: Q61WP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPG5 family.
messages: Cytoplasm
messages: Involved in autophagy. Has a role in the degradation of protein aggregates within autophagosomes. Essential for starvation-induced autotrophy and omegasome development (By similarity).

6238:CBG 09953
gene id: 6238:CBG_09953
uniprot id: G2J6N5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 12259
gene id: 6238:CBG_12259
uniprot id: A8XF42
names: Similarity
messages: Belongs to the peptidase S28 family.

6238:CBG 00335
gene id: 6238:CBG_00335
uniprot id: A8WMU9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

6238:CBG 00263
gene id: 6238:CBG_00263
uniprot id: A8WMK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 21895
gene id: 6238:CBG_21895
uniprot id: A8Y125
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

6238:CBG 07002
gene id: 6238:CBG_07002
uniprot id: A8X3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

6238:CBG 11916
gene id: 6238:CBG_11916
uniprot id: A8XEL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

6238:CBG 17637
gene id: 6238:CBG_17637
uniprot id: A8XRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

6238:CBG 03668
gene id: 6238:CBG_03668
uniprot id: A8WVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

6238:CBG 00337
gene id: 6238:CBG_00337
uniprot id: A8WMV1
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 01825
gene id: 6238:CBG_01825
uniprot id: A8WQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family.
messages: Component of the RNA exosome complex.
messages: Cytoplasm
messages: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
messages: Nucleus
messages: nucleolus

6238:CBG 01067
gene id: 6238:CBG_01067
uniprot id: Q5CAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 16158
gene id: 6238:CBG_16158
uniprot id: A8XNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

6238:CBG 16827
gene id: 6238:CBG_16827
uniprot id: A8XPW5
names: Subcellular Location Annotation
messages: cilium basal body

6238:CBG 11926
gene id: 6238:CBG_11926
uniprot id: A8XEL9
names: Similarity
messages: Belongs to the CD36 family.

6238:CBG 13401
gene id: 6238:CBG_13401
uniprot id: A8XHU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

6238:CBG 02460
gene id: 6238:CBG_02460
uniprot id: A8WU98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

6238:CBG 11998
gene id: 6238:CBG_11998
uniprot id: A8XEB2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 08489
gene id: 6238:CBG_08489
uniprot id: A8X6P3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09203
gene id: 6238:CBG_09203
uniprot id: Q9XTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

6238:CBG 20626
gene id: 6238:CBG_20626
uniprot id: A8XY86
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

6238:CBG 16375
gene id: 6238:CBG_16375
uniprot id: A8XNK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus
messages: Orphan nuclear receptor.

6238:CBG 00206
gene id: 6238:CBG_00206
uniprot id: A8WMH0
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 03104
gene id: 6238:CBG_03104
uniprot id: A8WSS5
names: Similarity
messages: Belongs to the adenylate kinase family.

6238:CBG 16962
gene id: 6238:CBG_16962
uniprot id: A8XQ53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 10155
gene id: 6238:CBG_10155
uniprot id: A8XAI2
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

6238:CBG 24741
gene id: 6238:CBG_24741
uniprot id: A8WLD4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

6238:CBG 02162
gene id: 6238:CBG_02162
uniprot id: A8WS33
names: Similarity
messages: Belongs to the actin family.

6238:CBG 06765
gene id: 6238:CBG_06765
uniprot id: A8X312
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 18635
gene id: 6238:CBG_18635
uniprot id: A8XTS1
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 17376
gene id: 6238:CBG_17376
uniprot id: A8XQX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions.
messages: gap junction

6238:CBG 11272
gene id: 6238:CBG_11272
uniprot id: A8XDE7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

6238:CBG 22165
gene id: 6238:CBG_22165
uniprot id: A8Y1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Catalyzes the transfer of galactose onto proteins or lipids. Required for susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-2 and bre-3 (By similarity).
messages: Membrane

6238:CBG 05109
gene id: 6238:CBG_05109
uniprot id: A8WZ85
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

6238:CBG 20174
gene id: 6238:CBG_20174
uniprot id: A8XX92
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Thought to act as a glyoxalase. May remove methylglyoxal from mitochondrial proteins. Has roles in reducing oxidative stress and increasing lifespan (By similarity).

6238:CBG 16815
gene id: 6238:CBG_16815
uniprot id: A8XPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

6238:CBG 15153
gene id: 6238:CBG_15153
uniprot id: P90726
names: Function
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes (By similarity).

6238:CBG 15774
gene id: 6238:CBG_15774
uniprot id: A8XMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

6238:CBG 14121
gene id: 6238:CBG_14121
uniprot id: A8XJC7
names: Similarity
messages: Belongs to the ACDP family.

6238:CBG 00496
gene id: 6238:CBG_00496
uniprot id: A8WMT1
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 06811
gene id: 6238:CBG_06811
uniprot id: A8X347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
messages: Secreted

6238:CBG 12658
gene id: 6238:CBG_12658
uniprot id: A8XG99
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

6238:CBG 01026
gene id: 6238:CBG_01026
uniprot id: A8WP29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 22193
gene id: 6238:CBG_22193
uniprot id: A8Y1R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

6238:CBG 12404
gene id: 6238:CBG_12404
uniprot id: Q61DP2
names: Function
names: Subcellular Location Annotation
messages: Required both for centrosome duplication and maturation. Required for pericentriolar material (PCM) recruitment.
messages: centriole

6238:CBG 17992
gene id: 6238:CBG_17992
uniprot id: A8XSR9
names: Similarity
messages: Belongs to the GIPC family.

6238:CBG 04100
gene id: 6238:CBG_04100
uniprot id: A8WW77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 18300
gene id: 6238:CBG_18300
uniprot id: A8XSD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

6238:CBG 12085
gene id: 6238:CBG_12085
uniprot id: A8XEI6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer.

6238:CBG 11553
gene id: 6238:CBG_11553
uniprot id: A8XDH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

6238:CBG 15746
gene id: 6238:CBG_15746
uniprot id: A8XMP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

6238:CBG 21207
gene id: 6238:CBG_21207
uniprot id: Q60RS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM16/PAM16 family.
messages: Mitochondrion inner membrane
messages: Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GrpE, tim-44, tim-16 and tim-14. Associates with the TIM23 complex.
messages: Regulates ATP-dependent protein translocation into the mitochondrial matrix.
messages: The J-like region, although related to the J domain does not have co-chaperone activity.

6238:CBG 05290
gene id: 6238:CBG_05290
uniprot id: A8WZJ6
names: Similarity
messages: Belongs to the nematode receptor-like protein srd family.

6238:CBG 12951
gene id: 6238:CBG_12951
uniprot id: A8XGR2
names: Similarity
messages: Belongs to the CDI family.

6238:CBG 23438
gene id: 6238:CBG_23438
uniprot id: G2J6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 02452
gene id: 6238:CBG_02452
uniprot id: A8WUA7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

6238:CBG 16982
gene id: 6238:CBG_16982
uniprot id: A8XQ70
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 14055
gene id: 6238:CBG_14055
uniprot id: Q619W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR (By similarity).

6238:CBG 21050
gene id: 6238:CBG_21050
uniprot id: A8XZA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 08386
gene id: 6238:CBG_08386
uniprot id: P34764
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifies differentiation of the set of six touch receptor neurons. Binds cooperatively as a heterodimer with unc-86 to sites in the mec-3 gene promoter.

6238:CBG 03063
gene id: 6238:CBG_03063
uniprot id: A8WSV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).
messages: Nucleus

6238:CBG 11431
gene id: 6238:CBG_11431
uniprot id: A8XD13
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 12757
gene id: 6238:CBG_12757
uniprot id: A8XGI2
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 05777
gene id: 6238:CBG_05777
uniprot id: A8X1N3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 14708
gene id: 6238:CBG_14708
uniprot id: A8XKI1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 12504
gene id: 6238:CBG_12504
uniprot id: A8XFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Mitochondrion

6238:CBG 02289
gene id: 6238:CBG_02289
uniprot id: A8WUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

6238:CBG 14711
gene id: 6238:CBG_14711
uniprot id: A8XKI2
names: Similarity
messages: Belongs to the arginase family.

6238:CBG 06810
gene id: 6238:CBG_06810
uniprot id: A8X346
names: Similarity
messages: Belongs to the AccD/PCCB family.

6238:CBG 14988
gene id: 6238:CBG_14988
uniprot id: A8XL58
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 01773
gene id: 6238:CBG_01773
uniprot id: A8WQV5
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 00829
gene id: 6238:CBG_00829
uniprot id: A8WNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 23516
gene id: 6238:CBG_23516
uniprot id: A8Y3Q8
names: Similarity
messages: Belongs to the peptidase C13 family.

6238:CBG 06387
gene id: 6238:CBG_06387
uniprot id: A8X243
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 11776
gene id: 6238:CBG_11776
uniprot id: A8XE00
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Methylation at the C-terminal Leu-333 is critical for interactions with regulatory subunits.
messages: Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulting in chiasma formation. During oocyte meiosis II and probably together with regulatory subunit ppfr-1, may regulate microtubule severing by dephosphorylating and activating mei-1, a component of the katanin microtubule severing complex.
messages: Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. The regulatory subunits are likely to be ppfr-1, ppfr-2, ppfr-4 and smk-1. Interacts with mei-1.
messages: centrosome

6238:CBG 06228
gene id: 6238:CBG_06228
uniprot id: Q61SD1
names: Function
names: Similarity
messages: Belongs to the MON2 family.
messages: May be required for traffic between late Golgi and early endosomes.

6238:CBG 12038
gene id: 6238:CBG_12038
uniprot id: A8XEE8
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

6238:CBG 08845
gene id: 6238:CBG_08845
uniprot id: A8X7I8
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 17826
gene id: 6238:CBG_17826
uniprot id: A8XRV2
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 10873
gene id: 6238:CBG_10873
uniprot id: A8XC66
names: Caution
names: Cofactor
names: Function
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Metalloprotease.

6238:CBG 01050
gene id: 6238:CBG_01050
uniprot id: A8WP07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

6238:CBG 07863
gene id: 6238:CBG_07863
uniprot id: A8X5A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

6238:CBG 20793
gene id: 6238:CBG_20793
uniprot id: A8XYM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 21241
gene id: 6238:CBG_21241
uniprot id: A8XZI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

6238:CBG 24273
gene id: 6238:CBG_24273
uniprot id: A8WKC7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

6238:CBG 11457
gene id: 6238:CBG_11457
uniprot id: A8XCZ1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

6238:CBG 20704
gene id: 6238:CBG_20704
uniprot id: A8XYF2
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 19303
gene id: 6238:CBG_19303
uniprot id: A8XVB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

6238:CBG 09594
gene id: 6238:CBG_09594
uniprot id: A8X8Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

6238:CBG 22670
gene id: 6238:CBG_22670
uniprot id: A8Y2U0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18897
gene id: 6238:CBG_18897
uniprot id: A8XUB2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.

6238:CBG 12184
gene id: 6238:CBG_12184
uniprot id: A8XF17
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 19478
gene id: 6238:CBG_19478
uniprot id: A8XVN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15416
gene id: 6238:CBG_15416
uniprot id: A8XMB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

6238:CBG 15826
gene id: 6238:CBG_15826
uniprot id: A8XMY0
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 12089
gene id: 6238:CBG_12089
uniprot id: A8XEJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

6238:CBG 22506
gene id: 6238:CBG_22506
uniprot id: A8Y2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Membrane

6238:CBG 03474
gene id: 6238:CBG_03474
uniprot id: A8WV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

6238:CBG 00321
gene id: 6238:CBG_00321
uniprot id: A8WMP9
names: Similarity
messages: Belongs to the RdRP family.

6238:CBG 18198
gene id: 6238:CBG_18198
uniprot id: A8XS51
names: Subcellular Location Annotation
messages: P-body

6238:CBG 12785
gene id: 6238:CBG_12785
uniprot id: A8XGK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

6238:CBG 22267
gene id: 6238:CBG_22267
uniprot id: A8Y1X8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

6238:CBG 15662
gene id: 6238:CBG_15662
uniprot id: A8XMH4
names: Similarity
messages: Belongs to the PHF5 family.

6238:CBG 19421
gene id: 6238:CBG_19421
uniprot id: A8XVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

6238:CBG 04204
gene id: 6238:CBG_04204
uniprot id: A8WWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 20986
gene id: 6238:CBG_20986
uniprot id: E3CU87
names: Caution
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15744
gene id: 6238:CBG_15744
uniprot id: A8XMP3
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

6238:CBG 01251
gene id: 6238:CBG_01251
uniprot id: A8WPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 22794
gene id: 6238:CBG_22794
uniprot id: A8Y2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

6238:CBG 05906
gene id: 6238:CBG_05906
uniprot id: A8X1D4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

6238:CBG 15813
gene id: 6238:CBG_15813
uniprot id: A8XMY7
names: Subcellular Location Annotation
messages: cytoskeleton

6238:CBG 03449
gene id: 6238:CBG_03449
uniprot id: A8WV33
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 13144
gene id: 6238:CBG_13144
uniprot id: A8XH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

6238:CBG 23019
gene id: 6238:CBG_23019
uniprot id: A8Y3F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 06212
gene id: 6238:CBG_06212
uniprot id: Q61SE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins (By similarity).
messages: Mitochondrion

6238:CBG 12032
gene id: 6238:CBG_12032
uniprot id: A8XEE3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20861
gene id: 6238:CBG_20861
uniprot id: A8XYT4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 12909
gene id: 6238:CBG_12909
uniprot id: A8XGN1
names: Similarity
messages: Belongs to the CDK5RAP3 family.

6238:CBG 22774
gene id: 6238:CBG_22774
uniprot id: A8Y2V4
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

6238:CBG 01477
gene id: 6238:CBG_01477
uniprot id: A8WQL3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

6238:CBG 10088
gene id: 6238:CBG_10088
uniprot id: A8XAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rheb family.
messages: Binds GTP and exhibits intrinsic GTPase activity.
messages: Cell membrane

6238:CBG 23195
gene id: 6238:CBG_23195
uniprot id: A8Y4H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

6238:CBG 03983
gene id: 6238:CBG_03983
uniprot id: A8WVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

6238:CBG 13527
gene id: 6238:CBG_13527
uniprot id: A8XI37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

6238:CBG 02605
gene id: 6238:CBG_02605
uniprot id: A8WTY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

6238:CBG 08066
gene id: 6238:CBG_08066
uniprot id: A8X5Q3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

6238:CBG 06187
gene id: 6238:CBG_06187
uniprot id: A8X0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 15340
gene id: 6238:CBG_15340
uniprot id: A8XLZ4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

6238:CBG 19087
gene id: 6238:CBG_19087
uniprot id: A8XUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 18203
gene id: 6238:CBG_18203
uniprot id: A8XS54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

6238:CBG 06130
gene id: 6238:CBG_06130
uniprot id: A8X0U4
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

6238:CBG 07026
gene id: 6238:CBG_07026
uniprot id: A8X3V8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior (By similarity).
messages: Phosphorylation leads to an increase in the catalytic activity.
messages: axon
messages: perinuclear region

6238:CBG 12482
gene id: 6238:CBG_12482
uniprot id: Q61DH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Mitochondrion

6238:CBG 01745
gene id: 6238:CBG_01745
uniprot id: A8WQY2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

6238:CBG 24746
gene id: 6238:CBG_24746
uniprot id: A8WLD9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

6238:CBG 00836
gene id: 6238:CBG_00836
uniprot id: A8WNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

6238:CBG 14479
gene id: 6238:CBG_14479
uniprot id: A8XK11
names: Similarity
messages: Belongs to the Rho GDI family.

6238:CBG 10430
gene id: 6238:CBG_10430
uniprot id: A8XB71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 14467
gene id: 6238:CBG_14467
uniprot id: A8XK04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

6238:CBG 10083
gene id: 6238:CBG_10083
uniprot id: A8XAC5
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 07451
gene id: 6238:CBG_07451
uniprot id: A8X4Q9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 20417
gene id: 6238:CBG_20417
uniprot id: A8XXR1
names: Similarity
messages: Belongs to the hexokinase family.

6238:CBG 09643
gene id: 6238:CBG_09643
uniprot id: Q61JT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (By similarity).
messages: Belongs to the VPS54 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex, also called VFT (VPS fifty-three) complex, composed of VPS51, VPS52, VPS53 and VPS54.
messages: trans-Golgi network

6238:CBG 20021
gene id: 6238:CBG_20021
uniprot id: A8XWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 00624
gene id: 6238:CBG_00624
uniprot id: A8WNF4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 02311
gene id: 6238:CBG_02311
uniprot id: A8WUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

6238:CBG 13458
gene id: 6238:CBG_13458
uniprot id: A8XHQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus
messages: This enzyme lacks one or more conserved metal-binding sites. It may be non-functional.

6238:CBG 05039
gene id: 6238:CBG_05039
uniprot id: A8WZ15
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 01337
gene id: 6238:CBG_01337
uniprot id: A8WQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 16081
gene id: 6238:CBG_16081
uniprot id: A8XN53
names: Similarity
messages: Belongs to the glutathione peroxidase family.

6238:CBG 03041
gene id: 6238:CBG_03041
uniprot id: A8WSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

6238:CBG 05925
gene id: 6238:CBG_05925
uniprot id: A8X1B6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 22606
gene id: 6238:CBG_22606
uniprot id: A8Y2N4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

6238:CBG 09700
gene id: 6238:CBG_09700
uniprot id: A8X8G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

6238:CBG 16937
gene id: 6238:CBG_16937
uniprot id: A8XQ37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 03402
gene id: 6238:CBG_03402
uniprot id: A8WUZ1
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

6238:CBG 10007
gene id: 6238:CBG_10007
uniprot id: A8XA58
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with cks-1 (By similarity).
messages: Nucleus
messages: Phosphorylation both activates and inactivates the enzyme depending on the site of phosphorylation.
messages: Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity).
messages: centrosome

6238:CBG 00556
gene id: 6238:CBG_00556
uniprot id: A8WNL5
names: Similarity
messages: Belongs to the SEC2 family.

6238:CBG 03654
gene id: 6238:CBG_03654
uniprot id: A8WVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

6238:CBG 16718
gene id: 6238:CBG_16718
uniprot id: A8XPP0
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 05038
gene id: 6238:CBG_05038
uniprot id: A8WZ14
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 22471
gene id: 6238:CBG_22471
uniprot id: A8Y2D2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 14921
gene id: 6238:CBG_14921
uniprot id: A8XL01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

6238:CBG 12291
gene id: 6238:CBG_12291
uniprot id: A8XF69
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

6238:CBG 20642
gene id: 6238:CBG_20642
uniprot id: A8XYA0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 03331
gene id: 6238:CBG_03331
uniprot id: A8WUT0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

6238:CBG 15204
gene id: 6238:CBG_15204
uniprot id: A8XLP2
names: Similarity
messages: Belongs to the PPP phosphatase family.

6238:CBG 17078
gene id: 6238:CBG_17078
uniprot id: A8XQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

6238:CBG 04928
gene id: 6238:CBG_04928
uniprot id: A8WYT9
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 01269
gene id: 6238:CBG_01269
uniprot id: A8WQ01
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 08171
gene id: 6238:CBG_08171
uniprot id: A8X5Z5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

6238:CBG 17228
gene id: 6238:CBG_17228
uniprot id: A8XQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

6238:CBG 01806
gene id: 6238:CBG_01806
uniprot id: P61865
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

6238:CBG 03930
gene id: 6238:CBG_03930
uniprot id: A8WVS5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

6238:CBG 07358
gene id: 6238:CBG_07358
uniprot id: A8X4Y2
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

6238:CBG 20741
gene id: 6238:CBG_20741
uniprot id: A8XYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 04076
gene id: 6238:CBG_04076
uniprot id: A8WW56
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 14608
gene id: 6238:CBG_14608
uniprot id: A8XKA3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

6238:CBG 06559
gene id: 6238:CBG_06559
uniprot id: A8X2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

6238:CBG 10559
gene id: 6238:CBG_10559
uniprot id: A8XBD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

6238:CBG 09253
gene id: 6238:CBG_09253
uniprot id: Q61KR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Can be divided into a N-terminal globular domain, a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. The P-domain binds one molecule of calcium with high affinity, whereas the acidic C-domain binds multiple calcium ions with low affinity (By similarity).
messages: Endoplasmic reticulum lumen
messages: Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress-induced neurodegeneration (By similarity).
messages: The interaction with glycans occurs through a binding site in the globular lectin domain.
messages: The zinc binding sites are localized to the N-domain.

6238:CBG 04066
gene id: 6238:CBG_04066
uniprot id: A8WW49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

6238:CBG 18096
gene id: 6238:CBG_18096
uniprot id: Q60YT5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with the cullin cul-3. Interacts with ubiquitin via its UBA-like domain. Interacts with ned-8/nedd8 (By similarity).
messages: Nucleus
messages: Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with rbx-1 to recruit the Nedd8-charged E2 enzyme to the cullin component of SCF-type complexes (By similarity).

6238:CBG 04341
gene id: 6238:CBG_04341
uniprot id: A8WXB3
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 12907
gene id: 6238:CBG_12907
uniprot id: A8XGM9
names: Similarity
messages: Belongs to the ubiquitin family.

6238:CBG 13223
gene id: 6238:CBG_13223
uniprot id: A8XHC0
names: Subunit
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.

6238:CBG 08827
gene id: 6238:CBG_08827
uniprot id: A8X7H4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

6238:CBG 09945
gene id: 6238:CBG_09945
uniprot id: A8XA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 00476
gene id: 6238:CBG_00476
uniprot id: A8WMR2
names: Similarity
messages: Belongs to the acid ceramidase family.

6238:CBG 03852
gene id: 6238:CBG_03852
uniprot id: A8WWX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Interacts with, and is activated by, tap-1.
messages: Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Stimulates the wrm-1/lit-1-dependent phosphorylation of pop-1 and plays a role in the initial nuclear accumulation of wrm-1 (By similarity).

6238:CBG 04115
gene id: 6238:CBG_04115
uniprot id: A8WW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

6238:CBG 02894
gene id: 6238:CBG_02894
uniprot id: A8WT97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

6238:CBG 21178
gene id: 6238:CBG_21178
uniprot id: A8XZP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

6238:CBG 02547
gene id: 6238:CBG_02547
uniprot id: A8WU25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 04324
gene id: 6238:CBG_04324
uniprot id: A8WX92
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 09818
gene id: 6238:CBG_09818
uniprot id: A8X9Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

6238:CBG 22044
gene id: 6238:CBG_22044
uniprot id: A8Y1E6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

6238:CBG 11796
gene id: 6238:CBG_11796
uniprot id: A8XE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

6238:CBG 09574
gene id: 6238:CBG_09574
uniprot id: A8X8S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

6238:CBG 20323
gene id: 6238:CBG_20323
uniprot id: A8XXJ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 04328
gene id: 6238:CBG_04328
uniprot id: A8WX97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 07928
gene id: 6238:CBG_07928
uniprot id: A8X5D8
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 03318
gene id: 6238:CBG_03318
uniprot id: A8WUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 20715
gene id: 6238:CBG_20715
uniprot id: A8XYG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 15224
gene id: 6238:CBG_15224
uniprot id: A8XLM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

6238:CBG 14362
gene id: 6238:CBG_14362
uniprot id: Q619C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Essential for the proper assembly and activity of V-ATPase (By similarity). Required maternally for early embryogenesis and zygotically during morphogenesis. Specifically, involved in the clearance of apoptotic cell corpses in embryos. Also, during embryonic development, the V-ATPase is required to repress fusion of epidermal cells probably by negatively regulating eff-1-mediated cell fusion. In neurons, required for necrotic cell death by promoting intracellular acidification. Required for cell death induced by hypoxia. Required for acidification of synaptic vesicles and the release of neurotransmitters from adult neurons (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits vah-19/Ac45 and vah-20/PRR.

6238:CBG 03821
gene id: 6238:CBG_03821
uniprot id: A8WWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

6238:CBG 16944
gene id: 6238:CBG_16944
uniprot id: A8XQ43
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 17334
gene id: 6238:CBG_17334
uniprot id: A8XQU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 19056
gene id: 6238:CBG_19056
uniprot id: A8XUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 08396
gene id: 6238:CBG_08396
uniprot id: A8X6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

6238:CBG 07740
gene id: 6238:CBG_07740
uniprot id: A8X467
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 19036
gene id: 6238:CBG_19036
uniprot id: A8XUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

6238:CBG 17990
gene id: 6238:CBG_17990
uniprot id: A8XSR7
names: Similarity
messages: Belongs to the maelstrom family.

6238:CBG 16956
gene id: 6238:CBG_16956
uniprot id: A8XQ51
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

6238:CBG 15026
gene id: 6238:CBG_15026
uniprot id: A8XL83
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

6238:CBG 06002
gene id: 6238:CBG_06002
uniprot id: A8X150
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

6238:CBG 10467
gene id: 6238:CBG_10467
uniprot id: A8XBA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 22523
gene id: 6238:CBG_22523
uniprot id: A8Y2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

6238:CBG 15213
gene id: 6238:CBG_15213
uniprot id: A8XLN4
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

6238:CBG 23151
gene id: 6238:CBG_23151
uniprot id: A8Y4K9
names: Subunit
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 22278
gene id: 6238:CBG_22278
uniprot id: A8Y1Y9
names: Similarity
messages: Belongs to the cuticular collagen family.

6238:CBG 19814
gene id: 6238:CBG_19814
uniprot id: A8XW88
names: Activity Regulation
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. cAMP subfamily.
messages: Binding of cAMP to kin-2 regulatory subunits induces dissociation of the heterotetramer. The released catalytic subunits are active and able to phosphorylate their substrates.
messages: Essential for larval development. Controls the rhythmic contraction of enteric muscles probably by regulating G-protein coupled receptor aex-2-mediated calcium influx in GABAergic DVB neurons. Plays a role in the control of oocyte meiotic maturation by gonadal sheath cells. May play a role in the regulation of neuromuscular junctions.
messages: Expressed at low levels in the embryo. Expression increases after hatching and during larval stages and is followed by a decrease in adults (at protein level).
messages: Heterotetramer composed of two regulatory subunits and two catalytic subunits.

6238:CBG 19251
gene id: 6238:CBG_19251
uniprot id: A8XV69
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

6238:CBG 00360
gene id: 6238:CBG_00360
uniprot id: A8WMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

6238:CBG 09596
gene id: 6238:CBG_09596
uniprot id: A8X8Q1
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 00852
gene id: 6238:CBG_00852
uniprot id: A8WPG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

6238:CBG 10474
gene id: 6238:CBG_10474
uniprot id: A8XBB0
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

6238:CBG 13377
gene id: 6238:CBG_13377
uniprot id: A8XHW9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

6238:CBG 12644
gene id: 6238:CBG_12644
uniprot id: A8XG86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

6238:CBG 04044
gene id: 6238:CBG_04044
uniprot id: A8WW27
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

6238:CBG 12256
gene id: 6238:CBG_12256
uniprot id: A8XF40
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

6238:CBG 12949
gene id: 6238:CBG_12949
uniprot id: G2J6S2
names: Similarity
messages: Belongs to the CDI family.

6238:CBG 23102
gene id: 6238:CBG_23102
uniprot id: A8Y4P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

6238:CBG 22339
gene id: 6238:CBG_22339
uniprot id: A8Y267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

6238:CBG 10895
gene id: 6238:CBG_10895
uniprot id: A8XC79
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 14763
gene id: 6238:CBG_14763
uniprot id: A8XKM2
names: Function
names: Similarity
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for the maintenance of touch receptor neurons and possibly other type of neurons involved in locomotion.

6238:CBG 02167
gene id: 6238:CBG_02167
uniprot id: A8WS37
names: Similarity
messages: Belongs to the actin family.

6238:CBG 00547
gene id: 6238:CBG_00547
uniprot id: A8WNM3
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

6238:CBG 01783
gene id: 6238:CBG_01783
uniprot id: A8WQU5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

6238:CBG 23481
gene id: 6238:CBG_23481
uniprot id: A8Y3T6
names: Similarity
messages: Belongs to the FAX family.

6238:CBG 12473
gene id: 6238:CBG_12473
uniprot id: A8XFU5
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 11756
gene id: 6238:CBG_11756
uniprot id: A8XDT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
messages: cytosol

6238:CBG 23909
gene id: 6238:CBG_23909
uniprot id: A8WJK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

6238:CBG 01010
gene id: 6238:CBG_01010
uniprot id: A8WP43
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 08510
gene id: 6238:CBG_08510
uniprot id: A8X6Q9
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

6238:CBG 06922
gene id: 6238:CBG_06922
uniprot id: A8X3D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

6238:CBG 24369
gene id: 6238:CBG_24369
uniprot id: G2J679
names: Similarity
messages: Belongs to the MAPRE family.

6238:CBG 13210
gene id: 6238:CBG_13210
uniprot id: A8XHB0
names: Similarity
messages: Belongs to the DENR family.

6238:CBG 00740
gene id: 6238:CBG_00740
uniprot id: A8WN63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

6238:CBG 06370
gene id: 6238:CBG_06370
uniprot id: A8X231
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

6238:CBG 11282
gene id: 6238:CBG_11282
uniprot id: A8XDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: extracellular matrix

6238:CBG 04239
gene id: 6238:CBG_04239
uniprot id: A8WX09
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

6238:CBG 08298
gene id: 6238:CBG_08298
uniprot id: A8X688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

6238:CBG 22089
gene id: 6238:CBG_22089
uniprot id: A8Y1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

6238:CBG 03169
gene id: 6238:CBG_03169
uniprot id: A8WSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

6238:CBG 07351
gene id: 6238:CBG_07351
uniprot id: A8X4Y7
names: Similarity
messages: Belongs to the UPF0585 family.

6238:CBG 13212
gene id: 6238:CBG_13212
uniprot id: A8XHB1
names: Similarity
messages: Belongs to the OSBP family.

6238:CBG 12483
gene id: 6238:CBG_12483
uniprot id: A8XFV4
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 04006
gene id: 6238:CBG_04006
uniprot id: B0K069
names: Similarity
messages: Belongs to the RdRP family.

6238:CBG 07732
gene id: 6238:CBG_07732
uniprot id: A8X474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

6238:CBG 02488
gene id: 6238:CBG_02488
uniprot id: A8WU73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

6238:CBG 05595
gene id: 6238:CBG_05595
uniprot id: A8X084
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

6238:CBG 18166
gene id: 6238:CBG_18166
uniprot id: A8XT62
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 01738
gene id: 6238:CBG_01738
uniprot id: A8WQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-1 targeting for degradation at the meiosis to mitosis transition via deneddylation of cul-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. Within the eIF-3 complex, interacts directly with eif-3.F. Component of the CSN complex, composed of csn-1, csn-2, csn-3, csn-4, csn-5, csn-6 and csn-7. Within the CSN complex, interacts directly with csn-1 and csn-4.
messages: Cytoplasm

6238:CBG 02432
gene id: 6238:CBG_02432
uniprot id: G2J6N5
names: Function
messages: Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.

6238:CBG 12968
gene id: 6238:CBG_12968
uniprot id: A8XGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

6238:CBG 01406
gene id: 6238:CBG_01406
uniprot id: A8WQC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 16693
gene id: 6238:CBG_16693
uniprot id: A8XPM4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

6238:CBG 05577
gene id: 6238:CBG_05577
uniprot id: A8X068
names: Subcellular Location Annotation
messages: Nucleus

6238:CBG 22273
gene id: 6238:CBG_22273
uniprot id: A8Y1Y4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

6238:CBG 09597
gene id: 6238:CBG_09597
uniprot id: A8X8Q0
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 08282
gene id: 6238:CBG_08282
uniprot id: Q4VYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 17948
gene id: 6238:CBG_17948
uniprot id: A8XSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

6238:CBG 05261
gene id: 6238:CBG_05261
uniprot id: A8WZH6
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 20923
gene id: 6238:CBG_20923
uniprot id: A8XYY8
names: Similarity
messages: Belongs to the SIN1 family.

6238:CBG 12933
gene id: 6238:CBG_12933
uniprot id: A8XGQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Nucleus

6238:CBG 00557
gene id: 6238:CBG_00557
uniprot id: A8WNL4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

6238:CBG 20942
gene id: 6238:CBG_20942
uniprot id: A8XZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 20955
gene id: 6238:CBG_20955
uniprot id: A8XZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode receptor-like protein sre family.
messages: Membrane

6238:CBG 21270
gene id: 6238:CBG_21270
uniprot id: A8XZQ8
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

6238:CBG 08570
gene id: 6238:CBG_08570
uniprot id: A8X738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

6238:CBG 03259
gene id: 6238:CBG_03259
uniprot id: A8WSF9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 22283
gene id: 6238:CBG_22283
uniprot id: A8Y1Z4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

6238:CBG 22599
gene id: 6238:CBG_22599
uniprot id: A8Y2M8
names: Similarity
messages: Belongs to the peptidase C1 family.

6238:CBG 04579
gene id: 6238:CBG_04579
uniprot id: A8WXZ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

6238:CBG 09125
gene id: 6238:CBG_09125
uniprot id: A8X854
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.

6238:CBG 06954
gene id: 6238:CBG_06954
uniprot id: A8X422
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 06252
gene id: 6238:CBG_06252
uniprot id: Q1M2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

6238:CBG 09355
gene id: 6238:CBG_09355
uniprot id: A8X9A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

6238:CBG 03419
gene id: 6238:CBG_03419
uniprot id: A8WV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 22508
gene id: 6238:CBG_22508
uniprot id: A8Y2F5
names: Caution
names: Function
names: Similarity
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 19207
gene id: 6238:CBG_19207
uniprot id: A8XV29
names: Similarity
messages: Belongs to the group II decarboxylase family.

6238:CBG 05657
gene id: 6238:CBG_05657
uniprot id: A8X0D3
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05893
gene id: 6238:CBG_05893
uniprot id: A8X1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

6238:CBG 01022
gene id: 6238:CBG_01022
uniprot id: A8WP33
names: Similarity
messages: Belongs to the arrestin family.

6238:CBG 11456
gene id: 6238:CBG_11456
uniprot id: A8XCZ2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

6238:CBG 22343
gene id: 6238:CBG_22343
uniprot id: A8Y270
names: Similarity
messages: Belongs to the UPF0375 family.

6238:CBG 11069
gene id: 6238:CBG_11069
uniprot id: A8XCC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

6238:CBG 15759
gene id: 6238:CBG_15759
uniprot id: Q615B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

6238:CBG 15879
gene id: 6238:CBG_15879
uniprot id: A8XN29
names: Similarity
messages: Belongs to the cytochrome P450 family.

6238:CBG 09797
gene id: 6238:CBG_09797
uniprot id: A8X9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

6238:CBG 12804
gene id: 6238:CBG_12804
uniprot id: Q61CQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPCS1 family.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit sec-11 and three accessory subunits spcs-1, spcs-2 and spcs-3. The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Dispensable for SPC enzymatic activity (By similarity).
messages: Endoplasmic reticulum membrane

6238:CBG 21805
gene id: 6238:CBG_21805
uniprot id: A8Y0U8
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 18191
gene id: 6238:CBG_18191
uniprot id: A8XT83
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

6238:CBG 15955
gene id: 6238:CBG_15955
uniprot id: Q614K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

6238:CBG 15152
gene id: 6238:CBG_15152
uniprot id: P90727
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Forms a heterodimer with the U2AF small subunit.
messages: Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity).
messages: Nucleus

6238:CBG 23978
gene id: 6238:CBG_23978
uniprot id: A8WJQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

6238:CBG 20664
gene id: 6238:CBG_20664
uniprot id: A8XYB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

6238:CBG 04116
gene id: 6238:CBG_04116
uniprot id: Q61X59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.
messages: Magnesium. Also active with cobalt or copper.
messages: Mitochondrion inner membrane

6238:CBG 09364
gene id: 6238:CBG_09364
uniprot id: A8X996
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Late endosome membrane

6238:CBG 01308
gene id: 6238:CBG_01308
uniprot id: A8WQ38
names: Similarity
messages: Belongs to the peptidase A1 family.

6238:CBG 13878
gene id: 6238:CBG_13878
uniprot id: Q61A92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synembryn family.
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins independently of G-protein coupled receptors. Acts by exchanging bound GDP for free GTP. Also able to activate the G(s)-alpha in synaptic signaling network. Plays a key role in asymmetric spindle positioning, a step for asymmetric cell division that generates cell diversity during development by activating G(i) alpha protein goa-1 and gpa-16 independently of G-protein coupled receptors (By similarity).
messages: cell cortex

6238:CBG 11768
gene id: 6238:CBG_11768
uniprot id: A8XE08
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

6238:CBG 10434
gene id: 6238:CBG_10434
uniprot id: A8XB74
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

6238:CBG 05724
gene id: 6238:CBG_05724
uniprot id: A8X1S9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

6238:CBG 09421
gene id: 6238:CBG_09421
uniprot id: A8X953
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 06538
gene id: 6238:CBG_06538
uniprot id: A8X2H0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

6238:CBG 18074
gene id: 6238:CBG_18074
uniprot id: A8XSZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

6238:CBG 06027
gene id: 6238:CBG_06027
uniprot id: A8X126
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

6238:CBG 10119
gene id: 6238:CBG_10119
uniprot id: A8XAF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E2-like enzyme which forms an intermediate with ufm-1. The intermediate is formed via a thioester linkage.
messages: Interacts with uba-5.

6238:CBG 03598
gene id: 6238:CBG_03598
uniprot id: A8WVF2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

6238:CBG 09840
gene id: 6238:CBG_09840
uniprot id: A8X9S2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

6238:CBG 04561
gene id: 6238:CBG_04561
uniprot id: A8WXX7
names: Similarity
messages: Belongs to the FAM50 family.

6238:CBG 21511
gene id: 6238:CBG_21511
uniprot id: A8Y0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Lysosome membrane

6238:CBG 00021
gene id: 6238:CBG_00021
uniprot id: A8WM57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

6238:CBG 19412
gene id: 6238:CBG_19412
uniprot id: A8XVJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nematode transthyretin-like family.
messages: Secreted

6238:CBG 19175
gene id: 6238:CBG_19175
uniprot id: A8XV03
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 09958
gene id: 6238:CBG_09958
uniprot id: A8XA17
names: Similarity
names: Subunit
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Homodimer.

6238:CBG 21741
gene id: 6238:CBG_21741
uniprot id: A8Y0L1
names: Similarity
messages: Belongs to the TGF-beta family.

6238:CBG 24614
gene id: 6238:CBG_24614
uniprot id: A8WL29
names: Subcellular Location Annotation
messages: Membrane

6238:CBG 05390
gene id: 6238:CBG_05390
uniprot id: A8WZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

6238:CBG 18275
gene id: 6238:CBG_18275
uniprot id: A8XSB3
names: Similarity
messages: Belongs to the LSM12 family.

6238:CBG 22355
gene id: 6238:CBG_22355
uniprot id: A8Y275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

6238:CBG 00342
gene id: 6238:CBG_00342
uniprot id: A8WMV5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

6238:CBG 21902
gene id: 6238:CBG_21902
uniprot id: A8Y197
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Required for positioning of the mitotic spindle (By similarity).
messages: Cytoplasm
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

6238:CBG 19953
gene id: 6238:CBG_19953
uniprot id: A8XWT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

6238:CBG 00041
gene id: 6238:CBG_00041
uniprot id: A8WM70
names: Similarity
messages: Belongs to the protein kinase superfamily.

6238:CBG 06762
gene id: 6238:CBG_06762
uniprot id: A8X309
names: Similarity
messages: Belongs to the nematode receptor-like protein srg family.

6238:CBG 07447
gene id: 6238:CBG_07447
uniprot id: A8X4R1
names: Similarity
names: Subunit
messages: Belongs to the cuticular collagen family.
messages: Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.

6238:CBG 13043
gene id: 6238:CBG_13043
uniprot id: A8XGY2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

6238:CBG 19422
gene id: 6238:CBG_19422
uniprot id: A8XVK7
names: Similarity
messages: Belongs to the RuvB family.

6238:CBG 16647
gene id: 6238:CBG_16647
uniprot id: A8XP79
names: Subcellular Location Annotation
messages: Secreted

6238:CBG 16139
gene id: 6238:CBG_16139
uniprot id: A8XP12
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

6238:CBG 01518
gene id: 6238:CBG_01518
uniprot id: A8WQI0
names: Similarity
messages: Belongs to the KCTD3 family.