61652:I6G83 RS14530
gene id: 61652:I6G83_RS14530
uniprot id: A0A447QRY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

61652:I6G83 RS14870
gene id: 61652:I6G83_RS14870
uniprot id: A0A448SX77
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

61652:I6G83 RS12105
gene id: 61652:I6G83_RS12105
uniprot id: A0A447QQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

61652:I6G83 RS07445
gene id: 61652:I6G83_RS07445
uniprot id: A0A4U9H9Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS03700
gene id: 61652:I6G83_RS03700
uniprot id: A0A126VEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

61652:I6G83 RS10625
gene id: 61652:I6G83_RS10625
uniprot id: A0A140F144
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

61652:I6G83 RS04890
gene id: 61652:I6G83_RS04890
uniprot id: A0A447QKH1
names: Similarity
messages: Belongs to the aspartokinase family.

61652:I6G83 RS06880
gene id: 61652:I6G83_RS06880
uniprot id: A0A126VF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

61652:I6G83 RS15620
gene id: 61652:I6G83_RS15620
uniprot id: A0A447QSL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS14650
gene id: 61652:I6G83_RS14650
uniprot id: A0A4V6JGT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

61652:I6G83 RS06820
gene id: 61652:I6G83_RS06820
uniprot id: A0A3S4H6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

61652:I6G83 RS00350
gene id: 61652:I6G83_RS00350
uniprot id: A0A447QGP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS10740
gene id: 61652:I6G83_RS10740
uniprot id: A0A4U9HBS3
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

61652:I6G83 RS23035
gene id: 61652:I6G83_RS23035
uniprot id: A0A4U9HN19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

61652:I6G83 RS10595
gene id: 61652:I6G83_RS10595
uniprot id: A0A126VP34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

61652:I6G83 RS14885
gene id: 61652:I6G83_RS14885
uniprot id: A0A447QS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

61652:I6G83 RS20350
gene id: 61652:I6G83_RS20350
uniprot id: A0A3S4FXV6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS00115
gene id: 61652:I6G83_RS00115
uniprot id: A0A4U9HPW3
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

61652:I6G83 RS23285
gene id: 61652:I6G83_RS23285
uniprot id: A0A4U9HPI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
messages: Belongs to the flk family.
messages: Cell inner membrane

61652:I6G83 RS04520
gene id: 61652:I6G83_RS04520
uniprot id: A0A448SB01
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

61652:I6G83 RS08225
gene id: 61652:I6G83_RS08225
uniprot id: A0A4U9H8G8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

61652:I6G83 RS00970
gene id: 61652:I6G83_RS00970
uniprot id: A0A126VGW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

61652:I6G83 RS04585
gene id: 61652:I6G83_RS04585
uniprot id: A0A126VEH3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

61652:I6G83 RS11245
gene id: 61652:I6G83_RS11245
uniprot id: A0A4U9HEK9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

61652:I6G83 RS12835
gene id: 61652:I6G83_RS12835
uniprot id: A0A448S0S3
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

61652:I6G83 RS06045
gene id: 61652:I6G83_RS06045
uniprot id: A0A4U9HXS3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

61652:I6G83 RS17770
gene id: 61652:I6G83_RS17770
uniprot id: A0A448ST41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

61652:I6G83 RS14210
gene id: 61652:I6G83_RS14210
uniprot id: A0A447QRK9
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

61652:I6G83 RS06475
gene id: 61652:I6G83_RS06475
uniprot id: A0A126VES3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

61652:I6G83 RS06705
gene id: 61652:I6G83_RS06705
uniprot id: A0A3S4JUK8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

61652:I6G83 RS08180
gene id: 61652:I6G83_RS08180
uniprot id: A0A3S4JV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS02195
gene id: 61652:I6G83_RS02195
uniprot id: A0A3S4X5M7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

61652:I6G83 RS15275
gene id: 61652:I6G83_RS15275
uniprot id: A0A126VLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

61652:I6G83 RS08360
gene id: 61652:I6G83_RS08360
uniprot id: A0A2X5AHA8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

61652:I6G83 RS21970
gene id: 61652:I6G83_RS21970
uniprot id: A0A4U9HKL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

61652:I6G83 RS20760
gene id: 61652:I6G83_RS20760
uniprot id: A0A4U9HJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

61652:I6G83 RS09780
gene id: 61652:I6G83_RS09780
uniprot id: A0A4U9H941
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS08090
gene id: 61652:I6G83_RS08090
uniprot id: A0A3S4H6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

61652:I6G83 RS18610
gene id: 61652:I6G83_RS18610
uniprot id: A0A4U9HI86
names: Similarity
messages: Belongs to the CcdB toxin family.

61652:I6G83 RS01170
gene id: 61652:I6G83_RS01170
uniprot id: A0A4U9HNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

61652:I6G83 RS13445
gene id: 61652:I6G83_RS13445
uniprot id: A0A448S0B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

61652:I6G83 RS13755
gene id: 61652:I6G83_RS13755
uniprot id: A0A4U9HBW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS03165
gene id: 61652:I6G83_RS03165
uniprot id: A0A448SCK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

61652:I6G83 RS12350
gene id: 61652:I6G83_RS12350
uniprot id: A0A140F0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

61652:I6G83 RS10065
gene id: 61652:I6G83_RS10065
uniprot id: A0A140F1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

61652:I6G83 RS06010
gene id: 61652:I6G83_RS06010
uniprot id: A0A4U9HWV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

61652:I6G83 RS16975
gene id: 61652:I6G83_RS16975
uniprot id: A0A126VKK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS04295
gene id: 61652:I6G83_RS04295
uniprot id: A0A448SB98
names: Similarity
messages: Belongs to the peptidase S1C family.

61652:I6G83 RS23395
gene id: 61652:I6G83_RS23395
uniprot id: A0A448SID7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

61652:I6G83 RS01615
gene id: 61652:I6G83_RS01615
uniprot id: A0A126VHG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

61652:I6G83 RS13910
gene id: 61652:I6G83_RS13910
uniprot id: A0A4U9HDR5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

61652:I6G83 RS19690
gene id: 61652:I6G83_RS19690
uniprot id: A0A126VJV7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

61652:I6G83 RS08345
gene id: 61652:I6G83_RS08345
uniprot id: A0A126VE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

61652:I6G83 RS10370
gene id: 61652:I6G83_RS10370
uniprot id: A0A3S4FYQ9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

61652:I6G83 RS06225
gene id: 61652:I6G83_RS06225
uniprot id: A0A2X5C4R2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

61652:I6G83 RS21715
gene id: 61652:I6G83_RS21715
uniprot id: A0A126VHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

61652:I6G83 RS11215
gene id: 61652:I6G83_RS11215
uniprot id: A0A4V6JGL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

61652:I6G83 RS23180
gene id: 61652:I6G83_RS23180
uniprot id: A0A4U9HPE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS16650
gene id: 61652:I6G83_RS16650
uniprot id: A0A126VKR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS14330
gene id: 61652:I6G83_RS14330
uniprot id: A0A3S4YI46
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

61652:I6G83 RS03950
gene id: 61652:I6G83_RS03950
uniprot id: A0A3S4WV54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

61652:I6G83 RS10690
gene id: 61652:I6G83_RS10690
uniprot id: A0A4U9HC73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

61652:I6G83 RS05240
gene id: 61652:I6G83_RS05240
uniprot id: A0A2X5CBR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

61652:I6G83 RS17555
gene id: 61652:I6G83_RS17555
uniprot id: A0A3S4JVR2
names: Similarity
messages: Belongs to the peptidase C40 family.

61652:I6G83 RS22240
gene id: 61652:I6G83_RS22240
uniprot id: A0A3S5F242
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

61652:I6G83 RS08660
gene id: 61652:I6G83_RS08660
uniprot id: A0A447QN04
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

61652:I6G83 RS21200
gene id: 61652:I6G83_RS21200
uniprot id: A0A447QCY3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

61652:I6G83 RS08720
gene id: 61652:I6G83_RS08720
uniprot id: A0A126VD46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

61652:I6G83 RS20485
gene id: 61652:I6G83_RS20485
uniprot id: A0A4U9HKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Periplasm

61652:I6G83 RS12795
gene id: 61652:I6G83_RS12795
uniprot id: A0A4V6YXR7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

61652:I6G83 RS06695
gene id: 61652:I6G83_RS06695
uniprot id: A0A126VDB1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS12945
gene id: 61652:I6G83_RS12945
uniprot id: A0A140EZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

61652:I6G83 RS04610
gene id: 61652:I6G83_RS04610
uniprot id: A0A2X5AFI6
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

61652:I6G83 RS22855
gene id: 61652:I6G83_RS22855
uniprot id: A0A126VHM8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

61652:I6G83 RS16655
gene id: 61652:I6G83_RS16655
uniprot id: A0A126VLC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

61652:I6G83 RS06445
gene id: 61652:I6G83_RS06445
uniprot id: A0A4U9HVT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

61652:I6G83 RS01340
gene id: 61652:I6G83_RS01340
uniprot id: A0A126VGN8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

61652:I6G83 RS02580
gene id: 61652:I6G83_RS02580
uniprot id: A0A126VFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS23135
gene id: 61652:I6G83_RS23135
uniprot id: A0A448SIR6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61652:I6G83 RS05115
gene id: 61652:I6G83_RS05115
uniprot id: A0A3S4GIW1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

61652:I6G83 RS21580
gene id: 61652:I6G83_RS21580
uniprot id: A0A4U9HJY7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

61652:I6G83 RS05690
gene id: 61652:I6G83_RS05690
uniprot id: A0A126VEB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS06780
gene id: 61652:I6G83_RS06780
uniprot id: A0A126VF76
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

61652:I6G83 RS06450
gene id: 61652:I6G83_RS06450
uniprot id: A0A126VDF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

61652:I6G83 RS21440
gene id: 61652:I6G83_RS21440
uniprot id: A0A4U9HJS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

61652:I6G83 RS16090
gene id: 61652:I6G83_RS16090
uniprot id: A0A4U9HF35
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

61652:I6G83 RS05770
gene id: 61652:I6G83_RS05770
uniprot id: A0A2X5BWE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

61652:I6G83 RS06855
gene id: 61652:I6G83_RS06855
uniprot id: A0A126VD86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

61652:I6G83 RS20160
gene id: 61652:I6G83_RS20160
uniprot id: A0A4U9HHL4
names: Similarity
messages: Belongs to the UPF0502 family.

61652:I6G83 RS12035
gene id: 61652:I6G83_RS12035
uniprot id: A0A4U9HAK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS17745
gene id: 61652:I6G83_RS17745
uniprot id: A0A4U9HF19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

61652:I6G83 RS00890
gene id: 61652:I6G83_RS00890
uniprot id: A0A3S4H4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

61652:I6G83 RS07030
gene id: 61652:I6G83_RS07030
uniprot id: A0A4U9H7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

61652:I6G83 RS13555
gene id: 61652:I6G83_RS13555
uniprot id: A0A4U9HBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

61652:I6G83 RS10585
gene id: 61652:I6G83_RS10585
uniprot id: A0A4U9H9U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

61652:I6G83 RS19360
gene id: 61652:I6G83_RS19360
uniprot id: A0A3S5ASZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

61652:I6G83 RS15105
gene id: 61652:I6G83_RS15105
uniprot id: A0A126VLM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

61652:I6G83 RS08455
gene id: 61652:I6G83_RS08455
uniprot id: A0A447QNB8
names: Similarity
messages: Belongs to the GARS family.

61652:I6G83 RS06485
gene id: 61652:I6G83_RS06485
uniprot id: A0A3S4WEF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

61652:I6G83 RS12025
gene id: 61652:I6G83_RS12025
uniprot id: A0A140F0G3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

61652:I6G83 RS16120
gene id: 61652:I6G83_RS16120
uniprot id: A0A4U9HD98
names: Similarity
messages: Belongs to the fabD family.

61652:I6G83 RS07730
gene id: 61652:I6G83_RS07730
uniprot id: A0A4U9H8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

61652:I6G83 RS19845
gene id: 61652:I6G83_RS19845
uniprot id: A0A4U9HJM5
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

61652:I6G83 RS08775
gene id: 61652:I6G83_RS08775
uniprot id: A0A447QMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

61652:I6G83 RS04025
gene id: 61652:I6G83_RS04025
uniprot id: A0A447QJL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS16835
gene id: 61652:I6G83_RS16835
uniprot id: A0A126VKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS00035
gene id: 61652:I6G83_RS00035
uniprot id: A0A4U9HNP4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

61652:I6G83 RS21090
gene id: 61652:I6G83_RS21090
uniprot id: A0A126VI96
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

61652:I6G83 RS01305
gene id: 61652:I6G83_RS01305
uniprot id: A0A4U9HP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

61652:I6G83 RS06860
gene id: 61652:I6G83_RS06860
uniprot id: A0A126VD83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

61652:I6G83 RS02895
gene id: 61652:I6G83_RS02895
uniprot id: A0A3S4FVN8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

61652:I6G83 RS07835
gene id: 61652:I6G83_RS07835
uniprot id: A0A4U9H890
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

61652:I6G83 RS19835
gene id: 61652:I6G83_RS19835
uniprot id: A0A4U9HH93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

61652:I6G83 RS09860
gene id: 61652:I6G83_RS09860
uniprot id: A0A4U9H960
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

61652:I6G83 RS11080
gene id: 61652:I6G83_RS11080
uniprot id: A0A140F0X2
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS22450
gene id: 61652:I6G83_RS22450
uniprot id: A0A3S4X8L3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

61652:I6G83 RS12370
gene id: 61652:I6G83_RS12370
uniprot id: A0A4U9HCT1
names: Similarity
messages: Belongs to the CdaR family.

61652:I6G83 RS08755
gene id: 61652:I6G83_RS08755
uniprot id: A0A447QMU0
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

61652:I6G83 RS04105
gene id: 61652:I6G83_RS04105
uniprot id: A0A126VEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS08105
gene id: 61652:I6G83_RS08105
uniprot id: A0A447QN53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

61652:I6G83 RS20735
gene id: 61652:I6G83_RS20735
uniprot id: A0A4U9HJE6
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

61652:I6G83 RS08575
gene id: 61652:I6G83_RS08575
uniprot id: A0A4U9H8F5
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

61652:I6G83 RS16675
gene id: 61652:I6G83_RS16675
uniprot id: A0A447QT68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

61652:I6G83 RS02960
gene id: 61652:I6G83_RS02960
uniprot id: A0A4U9HWG1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS01140
gene id: 61652:I6G83_RS01140
uniprot id: A0A126VGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

61652:I6G83 RS08865
gene id: 61652:I6G83_RS08865
uniprot id: A0A126VCP0
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS09730
gene id: 61652:I6G83_RS09730
uniprot id: A0A140F1L9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

61652:I6G83 RS05870
gene id: 61652:I6G83_RS05870
uniprot id: A0A3S4GBG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

61652:I6G83 RS23210
gene id: 61652:I6G83_RS23210
uniprot id: A0A126VH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS00140
gene id: 61652:I6G83_RS00140
uniprot id: A0A126VGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61652:I6G83 RS11095
gene id: 61652:I6G83_RS11095
uniprot id: A0A447QPL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

61652:I6G83 RS22185
gene id: 61652:I6G83_RS22185
uniprot id: A0A447QE61
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS16255
gene id: 61652:I6G83_RS16255
uniprot id: A0A447QT16
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

61652:I6G83 RS07400
gene id: 61652:I6G83_RS07400
uniprot id: A0A4U9H7S5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

61652:I6G83 RS14760
gene id: 61652:I6G83_RS14760
uniprot id: A0A448SXJ1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

61652:I6G83 RS06055
gene id: 61652:I6G83_RS06055
uniprot id: A0A447QLR3
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

61652:I6G83 RS19045
gene id: 61652:I6G83_RS19045
uniprot id: A0A448SQT4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS11630
gene id: 61652:I6G83_RS11630
uniprot id: A0A4U9HAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

61652:I6G83 RS01510
gene id: 61652:I6G83_RS01510
uniprot id: A0A448SFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

61652:I6G83 RS19785
gene id: 61652:I6G83_RS19785
uniprot id: A0A126VJ74
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

61652:I6G83 RS09640
gene id: 61652:I6G83_RS09640
uniprot id: A0A4U9H912
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

61652:I6G83 RS19005
gene id: 61652:I6G83_RS19005
uniprot id: A0A4U9HG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

61652:I6G83 RS05245
gene id: 61652:I6G83_RS05245
uniprot id: A0A447QKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

61652:I6G83 RS21100
gene id: 61652:I6G83_RS21100
uniprot id: A0A448SME8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

61652:I6G83 RS03340
gene id: 61652:I6G83_RS03340
uniprot id: A0A4V6JI75
names: Similarity
messages: Belongs to the YjdM family.

61652:I6G83 RS12010
gene id: 61652:I6G83_RS12010
uniprot id: A0A3S4WPD4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

61652:I6G83 RS12075
gene id: 61652:I6G83_RS12075
uniprot id: A0A3S4FTC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

61652:I6G83 RS12395
gene id: 61652:I6G83_RS12395
uniprot id: A0A4U9HB36
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

61652:I6G83 RS03660
gene id: 61652:I6G83_RS03660
uniprot id: A0A4U9HUK6
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

61652:I6G83 RS18585
gene id: 61652:I6G83_RS18585
uniprot id: A0A3S5ATP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

61652:I6G83 RS19805
gene id: 61652:I6G83_RS19805
uniprot id: A0A126VJG0
names: Similarity
messages: Belongs to the UPF0229 family.

61652:I6G83 RS13045
gene id: 61652:I6G83_RS13045
uniprot id: A0A140EZX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

61652:I6G83 RS18505
gene id: 61652:I6G83_RS18505
uniprot id: A0A126VL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS00540
gene id: 61652:I6G83_RS00540
uniprot id: A0A448SHB2
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS08700
gene id: 61652:I6G83_RS08700
uniprot id: A0A3S5DF90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

61652:I6G83 RS02675
gene id: 61652:I6G83_RS02675
uniprot id: A0A4U9HW36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS01690
gene id: 61652:I6G83_RS01690
uniprot id: A0A126VG09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

61652:I6G83 RS08970
gene id: 61652:I6G83_RS08970
uniprot id: A0A126VDI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS12335
gene id: 61652:I6G83_RS12335
uniprot id: A0A4U9HB98
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS15220
gene id: 61652:I6G83_RS15220
uniprot id: A0A4U9HEW6
names: Similarity
messages: Belongs to the peptidase M1 family.

61652:I6G83 RS19190
gene id: 61652:I6G83_RS19190
uniprot id: A0A3S4WNN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.

61652:I6G83 RS10465
gene id: 61652:I6G83_RS10465
uniprot id: A0A4U9H9L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

61652:I6G83 RS06770
gene id: 61652:I6G83_RS06770
uniprot id: A0A126VDH0
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS01230
gene id: 61652:I6G83_RS01230
uniprot id: A0A448SG13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

61652:I6G83 RS06460
gene id: 61652:I6G83_RS06460
uniprot id: A0A447QLI3
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

61652:I6G83 RS05575
gene id: 61652:I6G83_RS05575
uniprot id: A0A4V6JIJ6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

61652:I6G83 RS17050
gene id: 61652:I6G83_RS17050
uniprot id: A0A448STY8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

61652:I6G83 RS21495
gene id: 61652:I6G83_RS21495
uniprot id: A0A4U9HKD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS05785
gene id: 61652:I6G83_RS05785
uniprot id: A0A3S5F1H4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS05615
gene id: 61652:I6G83_RS05615
uniprot id: A0A126VE38
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

61652:I6G83 RS22190
gene id: 61652:I6G83_RS22190
uniprot id: A0A126VJM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

61652:I6G83 RS04510
gene id: 61652:I6G83_RS04510
uniprot id: A0A3S4HZU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS06285
gene id: 61652:I6G83_RS06285
uniprot id: A0A126VEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

61652:I6G83 RS12190
gene id: 61652:I6G83_RS12190
uniprot id: A0A4V6JGM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

61652:I6G83 RS05210
gene id: 61652:I6G83_RS05210
uniprot id: A0A126VFG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

61652:I6G83 RS12740
gene id: 61652:I6G83_RS12740
uniprot id: A0A4U9HAY9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

61652:I6G83 RS22380
gene id: 61652:I6G83_RS22380
uniprot id: A0A126VJ19
names: Similarity
messages: Belongs to the universal stress protein A family.

61652:I6G83 RS22835
gene id: 61652:I6G83_RS22835
uniprot id: A0A447QFJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

61652:I6G83 RS04370
gene id: 61652:I6G83_RS04370
uniprot id: A0A447QJX0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

61652:I6G83 RS19810
gene id: 61652:I6G83_RS19810
uniprot id: A0A3S4JWJ8
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

61652:I6G83 RS06290
gene id: 61652:I6G83_RS06290
uniprot id: A0A447QLD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

61652:I6G83 RS06640
gene id: 61652:I6G83_RS06640
uniprot id: A0A4U9HVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

61652:I6G83 RS10235
gene id: 61652:I6G83_RS10235
uniprot id: A0A4U9HDW6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS13120
gene id: 61652:I6G83_RS13120
uniprot id: A0A4U9HD67
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

61652:I6G83 RS14465
gene id: 61652:I6G83_RS14465
uniprot id: A0A447QRT7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS19955
gene id: 61652:I6G83_RS19955
uniprot id: A0A447QVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

61652:I6G83 RS04310
gene id: 61652:I6G83_RS04310
uniprot id: A0A126VF38
names: Similarity
messages: Belongs to the BolA/IbaG family.

61652:I6G83 RS20130
gene id: 61652:I6G83_RS20130
uniprot id: A0A4U9HHL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

61652:I6G83 RS19855
gene id: 61652:I6G83_RS19855
uniprot id: A0A3S4FXN5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

61652:I6G83 RS20720
gene id: 61652:I6G83_RS20720
uniprot id: A0A4U9HII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS17395
gene id: 61652:I6G83_RS17395
uniprot id: A0A4U9HJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

61652:I6G83 RS22945
gene id: 61652:I6G83_RS22945
uniprot id: A0A3S5DEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS14375
gene id: 61652:I6G83_RS14375
uniprot id: A0A140EZ91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS07180
gene id: 61652:I6G83_RS07180
uniprot id: A0A4U9HA93
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

61652:I6G83 RS15235
gene id: 61652:I6G83_RS15235
uniprot id: A0A126VMT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS15195
gene id: 61652:I6G83_RS15195
uniprot id: A0A448SWW1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

61652:I6G83 RS03815
gene id: 61652:I6G83_RS03815
uniprot id: A0A4U9HXH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

61652:I6G83 RS08420
gene id: 61652:I6G83_RS08420
uniprot id: A0A126VEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

61652:I6G83 RS12005
gene id: 61652:I6G83_RS12005
uniprot id: A0A3S5ADS7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

61652:I6G83 RS22435
gene id: 61652:I6G83_RS22435
uniprot id: A0A126VI99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS20950
gene id: 61652:I6G83_RS20950
uniprot id: A0A3S4X1B4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

61652:I6G83 RS03260
gene id: 61652:I6G83_RS03260
uniprot id: A0A4U9HU39
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS16550
gene id: 61652:I6G83_RS16550
uniprot id: A0A4U9HDU3
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

61652:I6G83 RS06265
gene id: 61652:I6G83_RS06265
uniprot id: A0A447QLF8
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS08365
gene id: 61652:I6G83_RS08365
uniprot id: A0A126VCN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

61652:I6G83 RS12255
gene id: 61652:I6G83_RS12255
uniprot id: A0A4U9HAP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS11545
gene id: 61652:I6G83_RS11545
uniprot id: A0A2X5BVV7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

61652:I6G83 RS10915
gene id: 61652:I6G83_RS10915
uniprot id: A0A140F0Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

61652:I6G83 RS01695
gene id: 61652:I6G83_RS01695
uniprot id: A0A126VG06
names: Similarity
messages: Belongs to the UPF0325 family.

61652:I6G83 RS10385
gene id: 61652:I6G83_RS10385
uniprot id: A0A4U9H9F3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

61652:I6G83 RS21600
gene id: 61652:I6G83_RS21600
uniprot id: A0A126VI66
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

61652:I6G83 RS14485
gene id: 61652:I6G83_RS14485
uniprot id: A0A4U9HCE9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

61652:I6G83 RS22470
gene id: 61652:I6G83_RS22470
uniprot id: A0A447QF41
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61652:I6G83 RS19600
gene id: 61652:I6G83_RS19600
uniprot id: A0A126VJ94
names: Similarity
messages: Belongs to the UPF0263 family.

61652:I6G83 RS22845
gene id: 61652:I6G83_RS22845
uniprot id: A0A447QFG3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS10890
gene id: 61652:I6G83_RS10890
uniprot id: A0A448S299
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

61652:I6G83 RS10090
gene id: 61652:I6G83_RS10090
uniprot id: A0A3S5DFB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

61652:I6G83 RS09235
gene id: 61652:I6G83_RS09235
uniprot id: A0A4U9H916
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

61652:I6G83 RS03090
gene id: 61652:I6G83_RS03090
uniprot id: A0A1L2F514
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

61652:I6G83 RS06835
gene id: 61652:I6G83_RS06835
uniprot id: A0A447QLS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

61652:I6G83 RS20965
gene id: 61652:I6G83_RS20965
uniprot id: A0A448SML0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

61652:I6G83 RS09565
gene id: 61652:I6G83_RS09565
uniprot id: A0A447QNW6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04490
gene id: 61652:I6G83_RS04490
uniprot id: A0A126VEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

61652:I6G83 RS06350
gene id: 61652:I6G83_RS06350
uniprot id: A0A4U9HVN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

61652:I6G83 RS23450
gene id: 61652:I6G83_RS23450
uniprot id: A0A126VHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

61652:I6G83 RS09010
gene id: 61652:I6G83_RS09010
uniprot id: A0A126VCL3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

61652:I6G83 RS06305
gene id: 61652:I6G83_RS06305
uniprot id: A0A4U9I0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

61652:I6G83 RS19585
gene id: 61652:I6G83_RS19585
uniprot id: A0A4U9HGZ6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04330
gene id: 61652:I6G83_RS04330
uniprot id: A0A447QJW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

61652:I6G83 RS02490
gene id: 61652:I6G83_RS02490
uniprot id: A0A447QIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61652:I6G83 RS01810
gene id: 61652:I6G83_RS01810
uniprot id: A0A4U9HPY3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

61652:I6G83 RS00610
gene id: 61652:I6G83_RS00610
uniprot id: A0A4U9HNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS14765
gene id: 61652:I6G83_RS14765
uniprot id: A0A3S4JUN0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

61652:I6G83 RS19640
gene id: 61652:I6G83_RS19640
uniprot id: A0A126VJW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS08615
gene id: 61652:I6G83_RS08615
uniprot id: A0A3S4FS01
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

61652:I6G83 RS00940
gene id: 61652:I6G83_RS00940
uniprot id: A0A447QHD7
names: Similarity
messages: Belongs to the YfgM family.

61652:I6G83 RS03095
gene id: 61652:I6G83_RS03095
uniprot id: A0A4U9HSW5
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS14770
gene id: 61652:I6G83_RS14770
uniprot id: A0A4U9HC95
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS22910
gene id: 61652:I6G83_RS22910
uniprot id: A0A126VHB5
names: Similarity
messages: Belongs to the catalase family.

61652:I6G83 RS09045
gene id: 61652:I6G83_RS09045
uniprot id: A0A126VC89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

61652:I6G83 RS22780
gene id: 61652:I6G83_RS22780
uniprot id: A0A4U9HLF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

61652:I6G83 RS01150
gene id: 61652:I6G83_RS01150
uniprot id: A0A126VGF8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

61652:I6G83 RS06700
gene id: 61652:I6G83_RS06700
uniprot id: A0A3S4GJL4
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

61652:I6G83 RS19820
gene id: 61652:I6G83_RS19820
uniprot id: A0A4U9HH86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

61652:I6G83 RS08585
gene id: 61652:I6G83_RS08585
uniprot id: A0A126VCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

61652:I6G83 RS06950
gene id: 61652:I6G83_RS06950
uniprot id: A0A4U9I194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS11240
gene id: 61652:I6G83_RS11240
uniprot id: A0A4U9HA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

61652:I6G83 RS14475
gene id: 61652:I6G83_RS14475
uniprot id: A0A4V6YXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

61652:I6G83 RS04540
gene id: 61652:I6G83_RS04540
uniprot id: A0A126VEI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

61652:I6G83 RS03790
gene id: 61652:I6G83_RS03790
uniprot id: A0A126VFR8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

61652:I6G83 RS21135
gene id: 61652:I6G83_RS21135
uniprot id: A0A126VK50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

61652:I6G83 RS10985
gene id: 61652:I6G83_RS10985
uniprot id: A0A140F0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

61652:I6G83 RS21175
gene id: 61652:I6G83_RS21175
uniprot id: A0A126VI53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

61652:I6G83 RS06940
gene id: 61652:I6G83_RS06940
uniprot id: A0A3S4FSH1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

61652:I6G83 RS00585
gene id: 61652:I6G83_RS00585
uniprot id: A0A126VH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

61652:I6G83 RS05565
gene id: 61652:I6G83_RS05565
uniprot id: A0A3S4GJ34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

61652:I6G83 RS08765
gene id: 61652:I6G83_RS08765
uniprot id: A0A126VDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

61652:I6G83 RS10190
gene id: 61652:I6G83_RS10190
uniprot id: A0A3S4WQ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS01685
gene id: 61652:I6G83_RS01685
uniprot id: A0A4U9HS41
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

61652:I6G83 RS23085
gene id: 61652:I6G83_RS23085
uniprot id: A0A448SJ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

61652:I6G83 RS05965
gene id: 61652:I6G83_RS05965
uniprot id: A0A3S4WTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

61652:I6G83 RS19140
gene id: 61652:I6G83_RS19140
uniprot id: A0A447QV12
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61652:I6G83 RS06910
gene id: 61652:I6G83_RS06910
uniprot id: A0A4U9HYQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

61652:I6G83 RS20360
gene id: 61652:I6G83_RS20360
uniprot id: A0A3S4JZR4
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS01060
gene id: 61652:I6G83_RS01060
uniprot id: A0A4U9HR01
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS00385
gene id: 61652:I6G83_RS00385
uniprot id: A0A126VGT9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61652:I6G83 RS07820
gene id: 61652:I6G83_RS07820
uniprot id: A0A4U9H817
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

61652:I6G83 RS01540
gene id: 61652:I6G83_RS01540
uniprot id: A0A3S4YR03
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

61652:I6G83 RS10030
gene id: 61652:I6G83_RS10030
uniprot id: A0A4U9H9V6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS08215
gene id: 61652:I6G83_RS08215
uniprot id: A0A126VCP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

61652:I6G83 RS20975
gene id: 61652:I6G83_RS20975
uniprot id: A0A447QCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

61652:I6G83 RS20825
gene id: 61652:I6G83_RS20825
uniprot id: A0A4U9HIC9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS06145
gene id: 61652:I6G83_RS06145
uniprot id: A0A4U9I0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

61652:I6G83 RS16510
gene id: 61652:I6G83_RS16510
uniprot id: A0A126VKZ6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS00620
gene id: 61652:I6G83_RS00620
uniprot id: A0A3S4HYG5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

61652:I6G83 RS12100
gene id: 61652:I6G83_RS12100
uniprot id: A0A4V6JH83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

61652:I6G83 RS11730
gene id: 61652:I6G83_RS11730
uniprot id: A0A3S4FZA2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS08185
gene id: 61652:I6G83_RS08185
uniprot id: A0A4U9H8T0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

61652:I6G83 RS01190
gene id: 61652:I6G83_RS01190
uniprot id: A0A126VI98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

61652:I6G83 RS00125
gene id: 61652:I6G83_RS00125
uniprot id: A0A4U9HNS4
names: Similarity
messages: Belongs to the isochorismate synthase family.

61652:I6G83 RS19670
gene id: 61652:I6G83_RS19670
uniprot id: A0A4U9HHP8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

61652:I6G83 RS17540
gene id: 61652:I6G83_RS17540
uniprot id: A0A126VMD1
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

61652:I6G83 RS20205
gene id: 61652:I6G83_RS20205
uniprot id: A0A3S5DFP3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS23075
gene id: 61652:I6G83_RS23075
uniprot id: A0A126VJ60
names: Similarity
messages: Belongs to the UPF0304 family.

61652:I6G83 RS09085
gene id: 61652:I6G83_RS09085
uniprot id: A0A447QNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

61652:I6G83 RS12500
gene id: 61652:I6G83_RS12500
uniprot id: A0A140F079
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

61652:I6G83 RS05080
gene id: 61652:I6G83_RS05080
uniprot id: A0A126VG27
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

61652:I6G83 RS15760
gene id: 61652:I6G83_RS15760
uniprot id: A0A447QSP8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

61652:I6G83 RS19495
gene id: 61652:I6G83_RS19495
uniprot id: A0A4U9HGW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

61652:I6G83 RS17025
gene id: 61652:I6G83_RS17025
uniprot id: A0A3S4G1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61652:I6G83 RS22555
gene id: 61652:I6G83_RS22555
uniprot id: A0A3S4FMX1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

61652:I6G83 RS19200
gene id: 61652:I6G83_RS19200
uniprot id: A0A448SQN5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

61652:I6G83 RS07195
gene id: 61652:I6G83_RS07195
uniprot id: A0A126VDX1
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

61652:I6G83 RS08020
gene id: 61652:I6G83_RS08020
uniprot id: A0A3S4I172
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

61652:I6G83 RS04775
gene id: 61652:I6G83_RS04775
uniprot id: A0A3S4WT19
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

61652:I6G83 RS04945
gene id: 61652:I6G83_RS04945
uniprot id: A0A4U9HTS8
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

61652:I6G83 RS05640
gene id: 61652:I6G83_RS05640
uniprot id: A0A4U9HZT3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

61652:I6G83 RS06470
gene id: 61652:I6G83_RS06470
uniprot id: A0A448S7V8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

61652:I6G83 RS19890
gene id: 61652:I6G83_RS19890
uniprot id: A0A2X5EI64
names: Similarity
messages: Belongs to the UPF0260 family.

61652:I6G83 RS10445
gene id: 61652:I6G83_RS10445
uniprot id: A0A4U9HA38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

61652:I6G83 RS12650
gene id: 61652:I6G83_RS12650
uniprot id: A0A4U9HFJ6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

61652:I6G83 RS01725
gene id: 61652:I6G83_RS01725
uniprot id: A0A4U9HS57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS11505
gene id: 61652:I6G83_RS11505
uniprot id: A0A3S4GDK9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

61652:I6G83 RS14700
gene id: 61652:I6G83_RS14700
uniprot id: A0A3S4GET4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

61652:I6G83 RS09290
gene id: 61652:I6G83_RS09290
uniprot id: A0A126VDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

61652:I6G83 RS04480
gene id: 61652:I6G83_RS04480
uniprot id: A0A447QK64
names: Similarity
messages: Belongs to the UPF0307 family.

61652:I6G83 RS10275
gene id: 61652:I6G83_RS10275
uniprot id: A0A126VPB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

61652:I6G83 RS10295
gene id: 61652:I6G83_RS10295
uniprot id: A0A140F1B8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

61652:I6G83 RS10130
gene id: 61652:I6G83_RS10130
uniprot id: A0A4U9H9R2
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04550
gene id: 61652:I6G83_RS04550
uniprot id: A0A126VEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

61652:I6G83 RS16590
gene id: 61652:I6G83_RS16590
uniprot id: A0A4V6JH05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

61652:I6G83 RS15085
gene id: 61652:I6G83_RS15085
uniprot id: A0A447QSC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS03940
gene id: 61652:I6G83_RS03940
uniprot id: A0A126VET3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

61652:I6G83 RS05205
gene id: 61652:I6G83_RS05205
uniprot id: A0A126VEL0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

61652:I6G83 RS05910
gene id: 61652:I6G83_RS05910
uniprot id: A0A4U9HV51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

61652:I6G83 RS20015
gene id: 61652:I6G83_RS20015
uniprot id: A0A126VJP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

61652:I6G83 RS04930
gene id: 61652:I6G83_RS04930
uniprot id: A0A447QKI5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

61652:I6G83 RS02745
gene id: 61652:I6G83_RS02745
uniprot id: A0A4U9HW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

61652:I6G83 RS20600
gene id: 61652:I6G83_RS20600
uniprot id: A0A126VIK5
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS06805
gene id: 61652:I6G83_RS06805
uniprot id: A0A126VD95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

61652:I6G83 RS03070
gene id: 61652:I6G83_RS03070
uniprot id: A0A4U9HSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS04345
gene id: 61652:I6G83_RS04345
uniprot id: A0A126VEM3
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

61652:I6G83 RS00060
gene id: 61652:I6G83_RS00060
uniprot id: A0A447QGK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

61652:I6G83 RS19145
gene id: 61652:I6G83_RS19145
uniprot id: A0A447QV25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

61652:I6G83 RS01845
gene id: 61652:I6G83_RS01845
uniprot id: A0A126VFX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS02690
gene id: 61652:I6G83_RS02690
uniprot id: A0A126VG93
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

61652:I6G83 RS10965
gene id: 61652:I6G83_RS10965
uniprot id: A0A3S5DFC2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

61652:I6G83 RS08825
gene id: 61652:I6G83_RS08825
uniprot id: A0A126VD26
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

61652:I6G83 RS20250
gene id: 61652:I6G83_RS20250
uniprot id: A0A3S4WZY9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

61652:I6G83 RS01940
gene id: 61652:I6G83_RS01940
uniprot id: A0A4U9HRD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

61652:I6G83 RS18730
gene id: 61652:I6G83_RS18730
uniprot id: A0A4U9HFZ6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61652:I6G83 RS17635
gene id: 61652:I6G83_RS17635
uniprot id: A0A126VMB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

61652:I6G83 RS00685
gene id: 61652:I6G83_RS00685
uniprot id: A0A126VHD2
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

61652:I6G83 RS05380
gene id: 61652:I6G83_RS05380
uniprot id: A0A4U9HUG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS00550
gene id: 61652:I6G83_RS00550
uniprot id: A0A448SHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61652:I6G83 RS18120
gene id: 61652:I6G83_RS18120
uniprot id: A0A3S4HAH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

61652:I6G83 RS12700
gene id: 61652:I6G83_RS12700
uniprot id: A0A447QQJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS12915
gene id: 61652:I6G83_RS12915
uniprot id: A0A447QQT3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

61652:I6G83 RS08875
gene id: 61652:I6G83_RS08875
uniprot id: A0A126VD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS04350
gene id: 61652:I6G83_RS04350
uniprot id: A0A2X4ZY78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

61652:I6G83 RS09335
gene id: 61652:I6G83_RS09335
uniprot id: A0A126VCF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS02205
gene id: 61652:I6G83_RS02205
uniprot id: A0A448SED8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

61652:I6G83 RS21215
gene id: 61652:I6G83_RS21215
uniprot id: A0A448SM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS20610
gene id: 61652:I6G83_RS20610
uniprot id: A0A126VJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS07075
gene id: 61652:I6G83_RS07075
uniprot id: A0A3S4I0V7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61652:I6G83 RS17810
gene id: 61652:I6G83_RS17810
uniprot id: A0A126VLL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS13090
gene id: 61652:I6G83_RS13090
uniprot id: A0A4V6JHA5
names: Cofactor
messages: Binds 2 manganese ions per subunit.

61652:I6G83 RS09390
gene id: 61652:I6G83_RS09390
uniprot id: A0A126VDB0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

61652:I6G83 RS11565
gene id: 61652:I6G83_RS11565
uniprot id: A0A4U9HEU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

61652:I6G83 RS10830
gene id: 61652:I6G83_RS10830
uniprot id: A0A4U9HA63
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

61652:I6G83 RS11280
gene id: 61652:I6G83_RS11280
uniprot id: A0A4U9HA26
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

61652:I6G83 RS16995
gene id: 61652:I6G83_RS16995
uniprot id: A0A4U9HE56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

61652:I6G83 RS08905
gene id: 61652:I6G83_RS08905
uniprot id: A0A126VE15
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS04895
gene id: 61652:I6G83_RS04895
uniprot id: A0A4U9HU29
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS10935
gene id: 61652:I6G83_RS10935
uniprot id: A0A140F0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS19910
gene id: 61652:I6G83_RS19910
uniprot id: A0A3S4JWK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

61652:I6G83 RS21145
gene id: 61652:I6G83_RS21145
uniprot id: A0A4V6JHI0
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

61652:I6G83 RS22565
gene id: 61652:I6G83_RS22565
uniprot id: A0A126VHJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

61652:I6G83 RS17375
gene id: 61652:I6G83_RS17375
uniprot id: A0A447QTU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS04205
gene id: 61652:I6G83_RS04205
uniprot id: A0A447QJS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

61652:I6G83 RS23250
gene id: 61652:I6G83_RS23250
uniprot id: A0A126VHE7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

61652:I6G83 RS12070
gene id: 61652:I6G83_RS12070
uniprot id: A0A3S4FZE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

61652:I6G83 RS01720
gene id: 61652:I6G83_RS01720
uniprot id: A0A4U9HUR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

61652:I6G83 RS06260
gene id: 61652:I6G83_RS06260
uniprot id: A0A447QL03
names: Similarity
messages: Belongs to the FBPase class 2 family.

61652:I6G83 RS02770
gene id: 61652:I6G83_RS02770
uniprot id: A0A447QIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

61652:I6G83 RS16045
gene id: 61652:I6G83_RS16045
uniprot id: A0A4U9HD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61652:I6G83 RS18335
gene id: 61652:I6G83_RS18335
uniprot id: A0A3S5F2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

61652:I6G83 RS12930
gene id: 61652:I6G83_RS12930
uniprot id: A0A3S5F122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

61652:I6G83 RS17805
gene id: 61652:I6G83_RS17805
uniprot id: A0A4U9HJS3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

61652:I6G83 RS18805
gene id: 61652:I6G83_RS18805
uniprot id: A0A126VJV8
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

61652:I6G83 RS16285
gene id: 61652:I6G83_RS16285
uniprot id: A0A4U9HD13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

61652:I6G83 RS14095
gene id: 61652:I6G83_RS14095
uniprot id: A0A448S0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS00230
gene id: 61652:I6G83_RS00230
uniprot id: A0A3S5ANH2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

61652:I6G83 RS20745
gene id: 61652:I6G83_RS20745
uniprot id: A0A126VIF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

61652:I6G83 RS15170
gene id: 61652:I6G83_RS15170
uniprot id: A0A126VNH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

61652:I6G83 RS05195
gene id: 61652:I6G83_RS05195
uniprot id: A0A126VG07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

61652:I6G83 RS13315
gene id: 61652:I6G83_RS13315
uniprot id: A0A4V6JGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

61652:I6G83 RS15950
gene id: 61652:I6G83_RS15950
uniprot id: A0A126VL58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

61652:I6G83 RS19270
gene id: 61652:I6G83_RS19270
uniprot id: A0A4U9HGL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS09365
gene id: 61652:I6G83_RS09365
uniprot id: A0A4U9HAW5
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-1109 that is involved in catalysis.

61652:I6G83 RS06675
gene id: 61652:I6G83_RS06675
uniprot id: A0A448S7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

61652:I6G83 RS04850
gene id: 61652:I6G83_RS04850
uniprot id: A0A448SAH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

61652:I6G83 RS02175
gene id: 61652:I6G83_RS02175
uniprot id: A0A3S4WUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

61652:I6G83 RS03060
gene id: 61652:I6G83_RS03060
uniprot id: A0A4U9HTW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

61652:I6G83 RS00320
gene id: 61652:I6G83_RS00320
uniprot id: A0A447QGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

61652:I6G83 RS22025
gene id: 61652:I6G83_RS22025
uniprot id: A0A4U9HL30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

61652:I6G83 RS13170
gene id: 61652:I6G83_RS13170
uniprot id: A0A447QR03
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

61652:I6G83 RS10870
gene id: 61652:I6G83_RS10870
uniprot id: A0A448S1W9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS23360
gene id: 61652:I6G83_RS23360
uniprot id: A0A4U9HMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS00065
gene id: 61652:I6G83_RS00065
uniprot id: A0A126VH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

61652:I6G83 RS23315
gene id: 61652:I6G83_RS23315
uniprot id: A0A4U9HNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

61652:I6G83 RS08310
gene id: 61652:I6G83_RS08310
uniprot id: A0A4U9H8B6
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

61652:I6G83 RS06120
gene id: 61652:I6G83_RS06120
uniprot id: A0A3S4XD68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

61652:I6G83 RS22525
gene id: 61652:I6G83_RS22525
uniprot id: A0A3S5F224
names: Similarity
messages: Belongs to the peptidase C40 family.

61652:I6G83 RS19595
gene id: 61652:I6G83_RS19595
uniprot id: A0A448SQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS23435
gene id: 61652:I6G83_RS23435
uniprot id: A0A448SI84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

61652:I6G83 RS22460
gene id: 61652:I6G83_RS22460
uniprot id: A0A126VHK2
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

61652:I6G83 RS22520
gene id: 61652:I6G83_RS22520
uniprot id: A0A126VHL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxT phosphotransferase family.
messages: Cell inner membrane
messages: Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).

61652:I6G83 RS14980
gene id: 61652:I6G83_RS14980
uniprot id: A0A126VNK2
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS19310
gene id: 61652:I6G83_RS19310
uniprot id: A0A4U9HGM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

61652:I6G83 RS00555
gene id: 61652:I6G83_RS00555
uniprot id: A0A4U9HN22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

61652:I6G83 RS19150
gene id: 61652:I6G83_RS19150
uniprot id: A0A126VLI6
names: Similarity
messages: Belongs to the UPF0482 family.

61652:I6G83 RS05710
gene id: 61652:I6G83_RS05710
uniprot id: A0A126VDS7
names: Similarity
messages: Belongs to the pirin family.

61652:I6G83 RS21465
gene id: 61652:I6G83_RS21465
uniprot id: A0A448SLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

61652:I6G83 RS17615
gene id: 61652:I6G83_RS17615
uniprot id: A0A3S4XNA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

61652:I6G83 RS10325
gene id: 61652:I6G83_RS10325
uniprot id: A0A4U9H9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with the regulatory subunit KefF.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

61652:I6G83 RS14630
gene id: 61652:I6G83_RS14630
uniprot id: A0A4U9HC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

61652:I6G83 RS16035
gene id: 61652:I6G83_RS16035
uniprot id: A0A126VL50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

61652:I6G83 RS13385
gene id: 61652:I6G83_RS13385
uniprot id: A0A4U9HBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

61652:I6G83 RS05030
gene id: 61652:I6G83_RS05030
uniprot id: A0A4U9HUD7
names: Similarity
messages: Belongs to the DprA/Smf family.

61652:I6G83 RS17420
gene id: 61652:I6G83_RS17420
uniprot id: A0A3S4JYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61652:I6G83 RS07790
gene id: 61652:I6G83_RS07790
uniprot id: A0A126VCV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

61652:I6G83 RS20290
gene id: 61652:I6G83_RS20290
uniprot id: A0A126VIW4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

61652:I6G83 RS15120
gene id: 61652:I6G83_RS15120
uniprot id: A0A4U9HCN8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

61652:I6G83 RS03880
gene id: 61652:I6G83_RS03880
uniprot id: A0A126VG63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

61652:I6G83 RS22990
gene id: 61652:I6G83_RS22990
uniprot id: A0A126VIQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

61652:I6G83 RS08850
gene id: 61652:I6G83_RS08850
uniprot id: A0A4U9HB35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

61652:I6G83 RS20065
gene id: 61652:I6G83_RS20065
uniprot id: A0A126VJN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

61652:I6G83 RS14970
gene id: 61652:I6G83_RS14970
uniprot id: A0A447QS15
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

61652:I6G83 RS13465
gene id: 61652:I6G83_RS13465
uniprot id: A0A4V6JHB7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

61652:I6G83 RS01035
gene id: 61652:I6G83_RS01035
uniprot id: A0A4U9HNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

61652:I6G83 RS07915
gene id: 61652:I6G83_RS07915
uniprot id: A0A126VD80
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

61652:I6G83 RS08260
gene id: 61652:I6G83_RS08260
uniprot id: A0A3S5AFZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

61652:I6G83 RS06655
gene id: 61652:I6G83_RS06655
uniprot id: A0A126VDC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS14370
gene id: 61652:I6G83_RS14370
uniprot id: A0A448SYE7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

61652:I6G83 RS16930
gene id: 61652:I6G83_RS16930
uniprot id: A0A126VKL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

61652:I6G83 RS19645
gene id: 61652:I6G83_RS19645
uniprot id: A0A4U9HHN9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS10630
gene id: 61652:I6G83_RS10630
uniprot id: A0A4V6YXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

61652:I6G83 RS10305
gene id: 61652:I6G83_RS10305
uniprot id: A0A3S4XA18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

61652:I6G83 RS18665
gene id: 61652:I6G83_RS18665
uniprot id: A0A4U9HGI1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61652:I6G83 RS11250
gene id: 61652:I6G83_RS11250
uniprot id: A0A140F0U2
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS06845
gene id: 61652:I6G83_RS06845
uniprot id: A0A126VEL9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS22430
gene id: 61652:I6G83_RS22430
uniprot id: A0A3S4JR83
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS10735
gene id: 61652:I6G83_RS10735
uniprot id: A0A140F123
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS07935
gene id: 61652:I6G83_RS07935
uniprot id: A0A3S4WDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

61652:I6G83 RS22680
gene id: 61652:I6G83_RS22680
uniprot id: A0A3S4WZG1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

61652:I6G83 RS17510
gene id: 61652:I6G83_RS17510
uniprot id: A0A447QTT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

61652:I6G83 RS13580
gene id: 61652:I6G83_RS13580
uniprot id: A0A3S4I3F1
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

61652:I6G83 RS21055
gene id: 61652:I6G83_RS21055
uniprot id: A0A126VIW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

61652:I6G83 RS10565
gene id: 61652:I6G83_RS10565
uniprot id: A0A140F155
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

61652:I6G83 RS04270
gene id: 61652:I6G83_RS04270
uniprot id: A0A126VEL7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

61652:I6G83 RS23205
gene id: 61652:I6G83_RS23205
uniprot id: A0A126VH56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

61652:I6G83 RS19350
gene id: 61652:I6G83_RS19350
uniprot id: A0A447QV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

61652:I6G83 RS21235
gene id: 61652:I6G83_RS21235
uniprot id: A0A3S4JQA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

61652:I6G83 RS12810
gene id: 61652:I6G83_RS12810
uniprot id: A0A140F025
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61652:I6G83 RS06625
gene id: 61652:I6G83_RS06625
uniprot id: A0A3S4JRE8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS22150
gene id: 61652:I6G83_RS22150
uniprot id: A0A4U9HLV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS14425
gene id: 61652:I6G83_RS14425
uniprot id: A0A4U9HC27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

61652:I6G83 RS05105
gene id: 61652:I6G83_RS05105
uniprot id: A0A126VF12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

61652:I6G83 RS02365
gene id: 61652:I6G83_RS02365
uniprot id: A0A448SE49
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

61652:I6G83 RS08735
gene id: 61652:I6G83_RS08735
uniprot id: A0A448S4C4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

61652:I6G83 RS19300
gene id: 61652:I6G83_RS19300
uniprot id: A0A4U9HH94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

61652:I6G83 RS14795
gene id: 61652:I6G83_RS14795
uniprot id: A0A126VM11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

61652:I6G83 RS15305
gene id: 61652:I6G83_RS15305
uniprot id: A0A3S4GN07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

61652:I6G83 RS16265
gene id: 61652:I6G83_RS16265
uniprot id: A0A4U9HDL7
names: Similarity
messages: Belongs to the cytochrome P450 family.

61652:I6G83 RS02715
gene id: 61652:I6G83_RS02715
uniprot id: A0A4U9HSF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

61652:I6G83 RS01520
gene id: 61652:I6G83_RS01520
uniprot id: A0A3S4H4Y3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

61652:I6G83 RS14205
gene id: 61652:I6G83_RS14205
uniprot id: A0A448S0A9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS13820
gene id: 61652:I6G83_RS13820
uniprot id: A0A4U9HC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

61652:I6G83 RS02565
gene id: 61652:I6G83_RS02565
uniprot id: A0A3S5F1R1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

61652:I6G83 RS08485
gene id: 61652:I6G83_RS08485
uniprot id: A0A4U9H8N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

61652:I6G83 RS12855
gene id: 61652:I6G83_RS12855
uniprot id: A0A140F016
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61652:I6G83 RS21210
gene id: 61652:I6G83_RS21210
uniprot id: A0A447QCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

61652:I6G83 RS15205
gene id: 61652:I6G83_RS15205
uniprot id: A0A4V6JGT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS19575
gene id: 61652:I6G83_RS19575
uniprot id: A0A3S5DFN5
names: Similarity
messages: Belongs to the YciI family.

61652:I6G83 RS18235
gene id: 61652:I6G83_RS18235
uniprot id: A0A4U9HHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

61652:I6G83 RS02845
gene id: 61652:I6G83_RS02845
uniprot id: A0A126VGP5
names: Similarity
messages: Belongs to the YggT family.

61652:I6G83 RS22065
gene id: 61652:I6G83_RS22065
uniprot id: A0A4U9HL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS08415
gene id: 61652:I6G83_RS08415
uniprot id: A0A4U9H8Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

61652:I6G83 RS08640
gene id: 61652:I6G83_RS08640
uniprot id: A0A126VE60
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

61652:I6G83 RS10255
gene id: 61652:I6G83_RS10255
uniprot id: A0A4U9H9M9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS11355
gene id: 61652:I6G83_RS11355
uniprot id: A0A140F0S9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

61652:I6G83 RS14535
gene id: 61652:I6G83_RS14535
uniprot id: A0A4U9HEG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

61652:I6G83 RS19390
gene id: 61652:I6G83_RS19390
uniprot id: A0A126VKR2
names: Similarity
messages: Belongs to the SUI1 family.

61652:I6G83 RS00395
gene id: 61652:I6G83_RS00395
uniprot id: A0A4U9HP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

61652:I6G83 RS12085
gene id: 61652:I6G83_RS12085
uniprot id: A0A4U9HAL7
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS10200
gene id: 61652:I6G83_RS10200
uniprot id: A0A4U9H9C1
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

61652:I6G83 RS19960
gene id: 61652:I6G83_RS19960
uniprot id: A0A126VKG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS00985
gene id: 61652:I6G83_RS00985
uniprot id: A0A126VGG8
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

61652:I6G83 RS05275
gene id: 61652:I6G83_RS05275
uniprot id: A0A126VE10
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

61652:I6G83 RS07085
gene id: 61652:I6G83_RS07085
uniprot id: A0A3S4XWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS01065
gene id: 61652:I6G83_RS01065
uniprot id: A0A126VHT7
names: Similarity
messages: Belongs to the P(II) protein family.

61652:I6G83 RS06105
gene id: 61652:I6G83_RS06105
uniprot id: A0A126VDN1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

61652:I6G83 RS07660
gene id: 61652:I6G83_RS07660
uniprot id: A0A126VCU6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS13930
gene id: 61652:I6G83_RS13930
uniprot id: A0A4U9HC57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS10555
gene id: 61652:I6G83_RS10555
uniprot id: A0A3S5DFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS12170
gene id: 61652:I6G83_RS12170
uniprot id: A0A4U9HAM9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS12790
gene id: 61652:I6G83_RS12790
uniprot id: A0A140F029
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

61652:I6G83 RS14420
gene id: 61652:I6G83_RS14420
uniprot id: A0A4U9HE16
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

61652:I6G83 RS10975
gene id: 61652:I6G83_RS10975
uniprot id: A0A447QPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

61652:I6G83 RS10100
gene id: 61652:I6G83_RS10100
uniprot id: A0A4U9H9A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

61652:I6G83 RS01025
gene id: 61652:I6G83_RS01025
uniprot id: A0A126VH84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS19970
gene id: 61652:I6G83_RS19970
uniprot id: A0A126VJ25
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS11610
gene id: 61652:I6G83_RS11610
uniprot id: A0A3S4GLF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

61652:I6G83 RS09000
gene id: 61652:I6G83_RS09000
uniprot id: A0A126VDZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

61652:I6G83 RS16985
gene id: 61652:I6G83_RS16985
uniprot id: A0A4V6JGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

61652:I6G83 RS17675
gene id: 61652:I6G83_RS17675
uniprot id: A0A126VKA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

61652:I6G83 RS01345
gene id: 61652:I6G83_RS01345
uniprot id: A0A447QI32
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

61652:I6G83 RS22080
gene id: 61652:I6G83_RS22080
uniprot id: A0A4U9HKQ0
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS18860
gene id: 61652:I6G83_RS18860
uniprot id: A0A4U9HII2
names: Similarity
messages: Belongs to the peptidase S33 family.

61652:I6G83 RS18550
gene id: 61652:I6G83_RS18550
uniprot id: A0A4U9HFR7
names: Similarity
messages: Belongs to the UPF0386 family.

61652:I6G83 RS02545
gene id: 61652:I6G83_RS02545
uniprot id: A0A126VFI9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

61652:I6G83 RS12660
gene id: 61652:I6G83_RS12660
uniprot id: A0A4U9HCZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

61652:I6G83 RS06095
gene id: 61652:I6G83_RS06095
uniprot id: A0A447QLM3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

61652:I6G83 RS01165
gene id: 61652:I6G83_RS01165
uniprot id: A0A126VH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

61652:I6G83 RS12995
gene id: 61652:I6G83_RS12995
uniprot id: A0A140EZY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

61652:I6G83 RS06930
gene id: 61652:I6G83_RS06930
uniprot id: A0A126VDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

61652:I6G83 RS06100
gene id: 61652:I6G83_RS06100
uniprot id: A0A3S4JUD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS23150
gene id: 61652:I6G83_RS23150
uniprot id: A0A126VH54
names: Subunit
messages: Homooctamer.

61652:I6G83 RS01840
gene id: 61652:I6G83_RS01840
uniprot id: A0A4U9HUX4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS19665
gene id: 61652:I6G83_RS19665
uniprot id: A0A4U9HH38
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

61652:I6G83 RS06440
gene id: 61652:I6G83_RS06440
uniprot id: A0A448S7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

61652:I6G83 RS22200
gene id: 61652:I6G83_RS22200
uniprot id: A0A3S4FMJ0
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

61652:I6G83 RS12405
gene id: 61652:I6G83_RS12405
uniprot id: A0A4U9HFD4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

61652:I6G83 RS09130
gene id: 61652:I6G83_RS09130
uniprot id: A0A126VDF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

61652:I6G83 RS17755
gene id: 61652:I6G83_RS17755
uniprot id: A0A447QU15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

61652:I6G83 RS12260
gene id: 61652:I6G83_RS12260
uniprot id: A0A447QQB1
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

61652:I6G83 RS05100
gene id: 61652:I6G83_RS05100
uniprot id: A0A447QKV1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

61652:I6G83 RS03900
gene id: 61652:I6G83_RS03900
uniprot id: A0A4U9HSH6
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

61652:I6G83 RS23060
gene id: 61652:I6G83_RS23060
uniprot id: A0A126VHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS21060
gene id: 61652:I6G83_RS21060
uniprot id: A0A3S4GEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

61652:I6G83 RS14855
gene id: 61652:I6G83_RS14855
uniprot id: A0A4U9HEB4
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

61652:I6G83 RS15795
gene id: 61652:I6G83_RS15795
uniprot id: A0A3S4FW14
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS20725
gene id: 61652:I6G83_RS20725
uniprot id: A0A447QW20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

61652:I6G83 RS05720
gene id: 61652:I6G83_RS05720
uniprot id: A0A4U9HUW1
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

61652:I6G83 RS22260
gene id: 61652:I6G83_RS22260
uniprot id: A0A4V6JHM7
names: Similarity
messages: Belongs to the DSD1 family.

61652:I6G83 RS14515
gene id: 61652:I6G83_RS14515
uniprot id: A0A4U9HE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

61652:I6G83 RS08445
gene id: 61652:I6G83_RS08445
uniprot id: A0A3S4XVG7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

61652:I6G83 RS04145
gene id: 61652:I6G83_RS04145
uniprot id: A0A447QJR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS02620
gene id: 61652:I6G83_RS02620
uniprot id: A0A448SDQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

61652:I6G83 RS20305
gene id: 61652:I6G83_RS20305
uniprot id: A0A4U9HHT7
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

61652:I6G83 RS16270
gene id: 61652:I6G83_RS16270
uniprot id: A0A448SUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

61652:I6G83 RS04135
gene id: 61652:I6G83_RS04135
uniprot id: A0A447QK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

61652:I6G83 RS00590
gene id: 61652:I6G83_RS00590
uniprot id: A0A3S4YRW0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

61652:I6G83 RS11090
gene id: 61652:I6G83_RS11090
uniprot id: A0A140F0X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

61652:I6G83 RS12475
gene id: 61652:I6G83_RS12475
uniprot id: A0A4U9HAY1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS16380
gene id: 61652:I6G83_RS16380
uniprot id: A0A4U9HDN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

61652:I6G83 RS16100
gene id: 61652:I6G83_RS16100
uniprot id: A0A3S4Y8F1
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

61652:I6G83 RS19750
gene id: 61652:I6G83_RS19750
uniprot id: A0A3S4GGQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

61652:I6G83 RS10530
gene id: 61652:I6G83_RS10530
uniprot id: A0A140F161
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

61652:I6G83 RS05120
gene id: 61652:I6G83_RS05120
uniprot id: A0A126VE39
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

61652:I6G83 RS11815
gene id: 61652:I6G83_RS11815
uniprot id: A0A3S4JTF1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS06685
gene id: 61652:I6G83_RS06685
uniprot id: A0A448S7M0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

61652:I6G83 RS20930
gene id: 61652:I6G83_RS20930
uniprot id: A0A447QCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS00510
gene id: 61652:I6G83_RS00510
uniprot id: A0A126VH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

61652:I6G83 RS13350
gene id: 61652:I6G83_RS13350
uniprot id: A0A140EZS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS09020
gene id: 61652:I6G83_RS09020
uniprot id: A0A2X5FGD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS17775
gene id: 61652:I6G83_RS17775
uniprot id: A0A126VK98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

61652:I6G83 RS19760
gene id: 61652:I6G83_RS19760
uniprot id: A0A4U9HHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

61652:I6G83 RS03740
gene id: 61652:I6G83_RS03740
uniprot id: A0A4U9HTQ6
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

61652:I6G83 RS03410
gene id: 61652:I6G83_RS03410
uniprot id: A0A447QJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS19445
gene id: 61652:I6G83_RS19445
uniprot id: A0A3S4I5X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

61652:I6G83 RS08690
gene id: 61652:I6G83_RS08690
uniprot id: A0A3S4JV98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61652:I6G83 RS18875
gene id: 61652:I6G83_RS18875
uniprot id: A0A4U9HG41
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS19405
gene id: 61652:I6G83_RS19405
uniprot id: A0A126VJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

61652:I6G83 RS20195
gene id: 61652:I6G83_RS20195
uniprot id: A0A126VKY0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

61652:I6G83 RS12730
gene id: 61652:I6G83_RS12730
uniprot id: A0A140F036
names: Similarity
messages: Belongs to the PhoH family.

61652:I6G83 RS12365
gene id: 61652:I6G83_RS12365
uniprot id: A0A3S4FUI3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61652:I6G83 RS03755
gene id: 61652:I6G83_RS03755
uniprot id: A0A126VF90
names: Similarity
messages: Belongs to the transglycosylase Slt family.

61652:I6G83 RS10270
gene id: 61652:I6G83_RS10270
uniprot id: A0A4U9HA00
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

61652:I6G83 RS17875
gene id: 61652:I6G83_RS17875
uniprot id: A0A447QU61
names: Similarity
messages: Belongs to the PspA/IM30 family.

61652:I6G83 RS08670
gene id: 61652:I6G83_RS08670
uniprot id: A0A126VCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

61652:I6G83 RS23405
gene id: 61652:I6G83_RS23405
uniprot id: A0A4U9HPP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS16910
gene id: 61652:I6G83_RS16910
uniprot id: A0A126VKR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

61652:I6G83 RS08080
gene id: 61652:I6G83_RS08080
uniprot id: A0A447QMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

61652:I6G83 RS22310
gene id: 61652:I6G83_RS22310
uniprot id: A0A4U9HQT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

61652:I6G83 RS13280
gene id: 61652:I6G83_RS13280
uniprot id: A0A4U9HBR9
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

61652:I6G83 RS21460
gene id: 61652:I6G83_RS21460
uniprot id: A0A126VI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

61652:I6G83 RS12295
gene id: 61652:I6G83_RS12295
uniprot id: A0A140F0B3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

61652:I6G83 RS22575
gene id: 61652:I6G83_RS22575
uniprot id: A0A126VIY4
names: Similarity
messages: Belongs to the UPF0352 family.

61652:I6G83 RS13495
gene id: 61652:I6G83_RS13495
uniprot id: A0A4U9HG54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS06325
gene id: 61652:I6G83_RS06325
uniprot id: A0A126VDZ7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

61652:I6G83 RS10510
gene id: 61652:I6G83_RS10510
uniprot id: A0A4U9H9Y9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

61652:I6G83 RS05215
gene id: 61652:I6G83_RS05215
uniprot id: A0A126VEZ1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

61652:I6G83 RS16165
gene id: 61652:I6G83_RS16165
uniprot id: A0A4U9HHX6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

61652:I6G83 RS09905
gene id: 61652:I6G83_RS09905
uniprot id: A0A447QNS8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS18570
gene id: 61652:I6G83_RS18570
uniprot id: A0A4U9HFS6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

61652:I6G83 RS21065
gene id: 61652:I6G83_RS21065
uniprot id: A0A448SMH8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

61652:I6G83 RS04290
gene id: 61652:I6G83_RS04290
uniprot id: A0A3S4WGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

61652:I6G83 RS10500
gene id: 61652:I6G83_RS10500
uniprot id: A0A4U9H9Y3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS11465
gene id: 61652:I6G83_RS11465
uniprot id: A0A3S4FZ64
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

61652:I6G83 RS02750
gene id: 61652:I6G83_RS02750
uniprot id: A0A4U9HTI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

61652:I6G83 RS00445
gene id: 61652:I6G83_RS00445
uniprot id: A0A4U9HQD6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS02570
gene id: 61652:I6G83_RS02570
uniprot id: A0A2X5CZ58
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

61652:I6G83 RS07540
gene id: 61652:I6G83_RS07540
uniprot id: A0A3S4FXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS08930
gene id: 61652:I6G83_RS08930
uniprot id: A0A447QNL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

61652:I6G83 RS15145
gene id: 61652:I6G83_RS15145
uniprot id: A0A126VLH8
names: Similarity
messages: Belongs to the UPF0434 family.

61652:I6G83 RS05895
gene id: 61652:I6G83_RS05895
uniprot id: A0A3S4GJ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

61652:I6G83 RS21550
gene id: 61652:I6G83_RS21550
uniprot id: A0A4U9HK28
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

61652:I6G83 RS11395
gene id: 61652:I6G83_RS11395
uniprot id: A0A3S4YIY5
names: Subunit
messages: Monomer.

61652:I6G83 RS07125
gene id: 61652:I6G83_RS07125
uniprot id: A0A4U9H9I8
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS14385
gene id: 61652:I6G83_RS14385
uniprot id: A0A140EZ88
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

61652:I6G83 RS08840
gene id: 61652:I6G83_RS08840
uniprot id: A0A126VCD3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

61652:I6G83 RS05155
gene id: 61652:I6G83_RS05155
uniprot id: A0A2X5CBN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

61652:I6G83 RS04630
gene id: 61652:I6G83_RS04630
uniprot id: A0A126VES4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04355
gene id: 61652:I6G83_RS04355
uniprot id: A0A4U9HTD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

61652:I6G83 RS07135
gene id: 61652:I6G83_RS07135
uniprot id: A0A4U9H853
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

61652:I6G83 RS12000
gene id: 61652:I6G83_RS12000
uniprot id: A0A140F0G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

61652:I6G83 RS05110
gene id: 61652:I6G83_RS05110
uniprot id: A0A2X5BVQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

61652:I6G83 RS08370
gene id: 61652:I6G83_RS08370
uniprot id: A0A126VEB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

61652:I6G83 RS23485
gene id: 61652:I6G83_RS23485
uniprot id: A0A4U9HNM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS16125
gene id: 61652:I6G83_RS16125
uniprot id: A0A126VL25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

61652:I6G83 RS00240
gene id: 61652:I6G83_RS00240
uniprot id: A0A4U9HMX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

61652:I6G83 RS01000
gene id: 61652:I6G83_RS01000
uniprot id: A0A3S4H4S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

61652:I6G83 RS18560
gene id: 61652:I6G83_RS18560
uniprot id: A0A4U9HI69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS20260
gene id: 61652:I6G83_RS20260
uniprot id: A0A4U9HID1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

61652:I6G83 RS06220
gene id: 61652:I6G83_RS06220
uniprot id: A0A4V6JIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

61652:I6G83 RS10210
gene id: 61652:I6G83_RS10210
uniprot id: A0A448S323
names: Similarity
messages: Belongs to the threonine synthase family.

61652:I6G83 RS07840
gene id: 61652:I6G83_RS07840
uniprot id: A0A4V6JGD8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

61652:I6G83 RS01680
gene id: 61652:I6G83_RS01680
uniprot id: A0A2X5ASQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

61652:I6G83 RS00990
gene id: 61652:I6G83_RS00990
uniprot id: A0A126VGS0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

61652:I6G83 RS02630
gene id: 61652:I6G83_RS02630
uniprot id: A0A448SDL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS01515
gene id: 61652:I6G83_RS01515
uniprot id: A0A4U9HPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

61652:I6G83 RS08505
gene id: 61652:I6G83_RS08505
uniprot id: A0A447QME1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

61652:I6G83 RS05165
gene id: 61652:I6G83_RS05165
uniprot id: A0A126VF02
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

61652:I6G83 RS22170
gene id: 61652:I6G83_RS22170
uniprot id: A0A448SKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

61652:I6G83 RS00380
gene id: 61652:I6G83_RS00380
uniprot id: A0A4U9HN43
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS21610
gene id: 61652:I6G83_RS21610
uniprot id: A0A4U9HKJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61652:I6G83 RS00665
gene id: 61652:I6G83_RS00665
uniprot id: A0A4V6JHW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

61652:I6G83 RS12595
gene id: 61652:I6G83_RS12595
uniprot id: A0A3S4H8H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

61652:I6G83 RS03835
gene id: 61652:I6G83_RS03835
uniprot id: A0A126VG73
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

61652:I6G83 RS08605
gene id: 61652:I6G83_RS08605
uniprot id: A0A3S4FXY0
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

61652:I6G83 RS10205
gene id: 61652:I6G83_RS10205
uniprot id: A0A4U9HBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

61652:I6G83 RS04635
gene id: 61652:I6G83_RS04635
uniprot id: A0A126VEG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS07680
gene id: 61652:I6G83_RS07680
uniprot id: A0A448S638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS11460
gene id: 61652:I6G83_RS11460
uniprot id: A0A447QPT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

61652:I6G83 RS05495
gene id: 61652:I6G83_RS05495
uniprot id: A0A126VE14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

61652:I6G83 RS02550
gene id: 61652:I6G83_RS02550
uniprot id: A0A4U9HQU9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS11840
gene id: 61652:I6G83_RS11840
uniprot id: A0A4U9HAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

61652:I6G83 RS10390
gene id: 61652:I6G83_RS10390
uniprot id: A0A448S2Y2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

61652:I6G83 RS04940
gene id: 61652:I6G83_RS04940
uniprot id: A0A447QKI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

61652:I6G83 RS00860
gene id: 61652:I6G83_RS00860
uniprot id: A0A4U9HNF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

61652:I6G83 RS11760
gene id: 61652:I6G83_RS11760
uniprot id: A0A448S1K7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

61652:I6G83 RS08650
gene id: 61652:I6G83_RS08650
uniprot id: A0A4V6JGF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

61652:I6G83 RS05480
gene id: 61652:I6G83_RS05480
uniprot id: A0A4V6JIG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

61652:I6G83 RS02255
gene id: 61652:I6G83_RS02255
uniprot id: A0A3S4FVG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

61652:I6G83 RS14090
gene id: 61652:I6G83_RS14090
uniprot id: A0A4U9HDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS00025
gene id: 61652:I6G83_RS00025
uniprot id: A0A4U9HSD1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS10540
gene id: 61652:I6G83_RS10540
uniprot id: A0A448S267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

61652:I6G83 RS02775
gene id: 61652:I6G83_RS02775
uniprot id: A0A126VFD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

61652:I6G83 RS10000
gene id: 61652:I6G83_RS10000
uniprot id: A0A3S4FSL5
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS05880
gene id: 61652:I6G83_RS05880
uniprot id: A0A2X5BY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

61652:I6G83 RS09325
gene id: 61652:I6G83_RS09325
uniprot id: A0A4U9H944
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

61652:I6G83 RS09930
gene id: 61652:I6G83_RS09930
uniprot id: A0A447QNV0
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS22985
gene id: 61652:I6G83_RS22985
uniprot id: A0A126VHM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

61652:I6G83 RS07640
gene id: 61652:I6G83_RS07640
uniprot id: A0A448S5X1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

61652:I6G83 RS09745
gene id: 61652:I6G83_RS09745
uniprot id: A0A448S3K9
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

61652:I6G83 RS16475
gene id: 61652:I6G83_RS16475
uniprot id: A0A3S4FVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

61652:I6G83 RS13790
gene id: 61652:I6G83_RS13790
uniprot id: A0A3S5F113
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS13190
gene id: 61652:I6G83_RS13190
uniprot id: A0A3S4H8Q2
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

61652:I6G83 RS03705
gene id: 61652:I6G83_RS03705
uniprot id: A0A4U9HXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

61652:I6G83 RS01030
gene id: 61652:I6G83_RS01030
uniprot id: A0A126VGF9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

61652:I6G83 RS16970
gene id: 61652:I6G83_RS16970
uniprot id: A0A447QTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

61652:I6G83 RS12640
gene id: 61652:I6G83_RS12640
uniprot id: A0A2X5BXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

61652:I6G83 RS17840
gene id: 61652:I6G83_RS17840
uniprot id: A0A448SSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

61652:I6G83 RS03785
gene id: 61652:I6G83_RS03785
uniprot id: A0A4V6YXY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

61652:I6G83 RS12880
gene id: 61652:I6G83_RS12880
uniprot id: A0A4U9HBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

61652:I6G83 RS06255
gene id: 61652:I6G83_RS06255
uniprot id: A0A126VDS8
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

61652:I6G83 RS02705
gene id: 61652:I6G83_RS02705
uniprot id: A0A126VFS6
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

61652:I6G83 RS05580
gene id: 61652:I6G83_RS05580
uniprot id: A0A3S4FWN0
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS15280
gene id: 61652:I6G83_RS15280
uniprot id: A0A3S4GF26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

61652:I6G83 RS14675
gene id: 61652:I6G83_RS14675
uniprot id: A0A448SXU2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

61652:I6G83 RS17525
gene id: 61652:I6G83_RS17525
uniprot id: A0A126VKJ5
names: Similarity
messages: Belongs to the CFA/CMAS family.

61652:I6G83 RS12715
gene id: 61652:I6G83_RS12715
uniprot id: A0A4U9HB21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS20750
gene id: 61652:I6G83_RS20750
uniprot id: A0A4U9HKR6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

61652:I6G83 RS05305
gene id: 61652:I6G83_RS05305
uniprot id: A0A4U9HZE6
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

61652:I6G83 RS01945
gene id: 61652:I6G83_RS01945
uniprot id: A0A4U9HQ44
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS01185
gene id: 61652:I6G83_RS01185
uniprot id: A0A4U9HPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

61652:I6G83 RS23005
gene id: 61652:I6G83_RS23005
uniprot id: A0A126VH89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

61652:I6G83 RS17795
gene id: 61652:I6G83_RS17795
uniprot id: A0A3S4HAE4
names: Similarity
messages: Belongs to the glyoxalase I family.

61652:I6G83 RS14755
gene id: 61652:I6G83_RS14755
uniprot id: A0A4U9HC56
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

61652:I6G83 RS07770
gene id: 61652:I6G83_RS07770
uniprot id: A0A3S4I137
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

61652:I6G83 RS05130
gene id: 61652:I6G83_RS05130
uniprot id: A0A447QK97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

61652:I6G83 RS04965
gene id: 61652:I6G83_RS04965
uniprot id: A0A4U9HU71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

61652:I6G83 RS01765
gene id: 61652:I6G83_RS01765
uniprot id: A0A3S4HZ03
names: Similarity
messages: Belongs to the SufE family.

61652:I6G83 RS21255
gene id: 61652:I6G83_RS21255
uniprot id: A0A3S4JLK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

61652:I6G83 RS14975
gene id: 61652:I6G83_RS14975
uniprot id: A0A447QS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

61652:I6G83 RS10805
gene id: 61652:I6G83_RS10805
uniprot id: A0A4U9H9S6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04455
gene id: 61652:I6G83_RS04455
uniprot id: A0A126VEM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

61652:I6G83 RS09070
gene id: 61652:I6G83_RS09070
uniprot id: A0A126VCK6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

61652:I6G83 RS06295
gene id: 61652:I6G83_RS06295
uniprot id: A0A126VDH3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

61652:I6G83 RS12505
gene id: 61652:I6G83_RS12505
uniprot id: A0A4U9HAU2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS18995
gene id: 61652:I6G83_RS18995
uniprot id: A0A4U9HG91
names: Similarity
messages: Belongs to the hyi family.

61652:I6G83 RS16275
gene id: 61652:I6G83_RS16275
uniprot id: A0A4U9HFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS13235
gene id: 61652:I6G83_RS13235
uniprot id: A0A3S4JX01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS10635
gene id: 61652:I6G83_RS10635
uniprot id: A0A4U9HA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

61652:I6G83 RS21080
gene id: 61652:I6G83_RS21080
uniprot id: A0A126VI79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

61652:I6G83 RS01495
gene id: 61652:I6G83_RS01495
uniprot id: A0A448SFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

61652:I6G83 RS06300
gene id: 61652:I6G83_RS06300
uniprot id: A0A126VDR8
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS00880
gene id: 61652:I6G83_RS00880
uniprot id: A0A3S4FPA2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

61652:I6G83 RS13025
gene id: 61652:I6G83_RS13025
uniprot id: A0A2X5BZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

61652:I6G83 RS11255
gene id: 61652:I6G83_RS11255
uniprot id: A0A126VNR2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

61652:I6G83 RS19720
gene id: 61652:I6G83_RS19720
uniprot id: A0A3S4G2L9
names: Similarity
messages: Belongs to the LOG family.

61652:I6G83 RS19380
gene id: 61652:I6G83_RS19380
uniprot id: A0A126VJG6
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

61652:I6G83 RS14430
gene id: 61652:I6G83_RS14430
uniprot id: A0A447QRP1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS16750
gene id: 61652:I6G83_RS16750
uniprot id: A0A126VLA4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS07005
gene id: 61652:I6G83_RS07005
uniprot id: A0A448S732
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

61652:I6G83 RS22760
gene id: 61652:I6G83_RS22760
uniprot id: A0A4U9HNL8
names: Similarity
messages: Belongs to the GcvT family.

61652:I6G83 RS09100
gene id: 61652:I6G83_RS09100
uniprot id: A0A4U9HD47
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS15095
gene id: 61652:I6G83_RS15095
uniprot id: A0A3S5DFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

61652:I6G83 RS12620
gene id: 61652:I6G83_RS12620
uniprot id: A0A447QQM0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

61652:I6G83 RS19940
gene id: 61652:I6G83_RS19940
uniprot id: A0A3S4GPS8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

61652:I6G83 RS22895
gene id: 61652:I6G83_RS22895
uniprot id: A0A3S4JMX9
names: Similarity
messages: Belongs to the CinA family.

61652:I6G83 RS18985
gene id: 61652:I6G83_RS18985
uniprot id: A0A4U9HGV5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

61652:I6G83 RS05015
gene id: 61652:I6G83_RS05015
uniprot id: A0A126VEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

61652:I6G83 RS23400
gene id: 61652:I6G83_RS23400
uniprot id: A0A3S5DEW8
names: Similarity
messages: Belongs to the UPF0381 family.

61652:I6G83 RS03245
gene id: 61652:I6G83_RS03245
uniprot id: A0A4U9HT19
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS12050
gene id: 61652:I6G83_RS12050
uniprot id: A0A3S4WB61
names: Similarity
messages: Belongs to the UPF0234 family.

61652:I6G83 RS22720
gene id: 61652:I6G83_RS22720
uniprot id: A0A4U9HLW6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

61652:I6G83 RS01245
gene id: 61652:I6G83_RS01245
uniprot id: A0A4U9HP27
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

61652:I6G83 RS07890
gene id: 61652:I6G83_RS07890
uniprot id: A0A3S4H6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

61652:I6G83 RS03455
gene id: 61652:I6G83_RS03455
uniprot id: A0A4U9HX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS12110
gene id: 61652:I6G83_RS12110
uniprot id: A0A3S5F130
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

61652:I6G83 RS10280
gene id: 61652:I6G83_RS10280
uniprot id: A0A4U9HBY5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

61652:I6G83 RS10680
gene id: 61652:I6G83_RS10680
uniprot id: A0A140F134
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

61652:I6G83 RS01930
gene id: 61652:I6G83_RS01930
uniprot id: A0A126VGC4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

61652:I6G83 RS08570
gene id: 61652:I6G83_RS08570
uniprot id: A0A4U9H8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

61652:I6G83 RS22535
gene id: 61652:I6G83_RS22535
uniprot id: A0A3S4G885
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS19420
gene id: 61652:I6G83_RS19420
uniprot id: A0A126VLE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

61652:I6G83 RS11000
gene id: 61652:I6G83_RS11000
uniprot id: A0A447QPJ3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS14750
gene id: 61652:I6G83_RS14750
uniprot id: A0A4U9HCG0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

61652:I6G83 RS00855
gene id: 61652:I6G83_RS00855
uniprot id: A0A4U9HQM3
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

61652:I6G83 RS16205
gene id: 61652:I6G83_RS16205
uniprot id: A0A126VL11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoB family.
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

61652:I6G83 RS19545
gene id: 61652:I6G83_RS19545
uniprot id: A0A448SQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

61652:I6G83 RS21590
gene id: 61652:I6G83_RS21590
uniprot id: A0A4U9HM97
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

61652:I6G83 RS04235
gene id: 61652:I6G83_RS04235
uniprot id: A0A448SBE8
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

61652:I6G83 RS00580
gene id: 61652:I6G83_RS00580
uniprot id: A0A3S5F1X7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

61652:I6G83 RS04800
gene id: 61652:I6G83_RS04800
uniprot id: A0A126VEC8
names: Similarity
messages: Belongs to the Fur family.

61652:I6G83 RS03465
gene id: 61652:I6G83_RS03465
uniprot id: A0A3S4WTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS07675
gene id: 61652:I6G83_RS07675
uniprot id: A0A3S4GC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

61652:I6G83 RS08115
gene id: 61652:I6G83_RS08115
uniprot id: A0A448S571
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

61652:I6G83 RS09560
gene id: 61652:I6G83_RS09560
uniprot id: A0A3S4FSE6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS08055
gene id: 61652:I6G83_RS08055
uniprot id: A0A4U9H8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

61652:I6G83 RS19195
gene id: 61652:I6G83_RS19195
uniprot id: A0A126VJI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS05885
gene id: 61652:I6G83_RS05885
uniprot id: A0A126VFM9
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

61652:I6G83 RS01120
gene id: 61652:I6G83_RS01120
uniprot id: A0A4U9HNV8
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

61652:I6G83 RS04365
gene id: 61652:I6G83_RS04365
uniprot id: A0A126VFY3
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

61652:I6G83 RS10845
gene id: 61652:I6G83_RS10845
uniprot id: A0A447QPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS06115
gene id: 61652:I6G83_RS06115
uniprot id: A0A2X5FKJ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

61652:I6G83 RS23170
gene id: 61652:I6G83_RS23170
uniprot id: A0A447QG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

61652:I6G83 RS21530
gene id: 61652:I6G83_RS21530
uniprot id: A0A126VIA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

61652:I6G83 RS12850
gene id: 61652:I6G83_RS12850
uniprot id: A0A447QQR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

61652:I6G83 RS01010
gene id: 61652:I6G83_RS01010
uniprot id: A0A126VGI6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

61652:I6G83 RS06815
gene id: 61652:I6G83_RS06815
uniprot id: A0A126VDH7
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

61652:I6G83 RS11970
gene id: 61652:I6G83_RS11970
uniprot id: A0A140F0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

61652:I6G83 RS04580
gene id: 61652:I6G83_RS04580
uniprot id: A0A126VET4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

61652:I6G83 RS08960
gene id: 61652:I6G83_RS08960
uniprot id: A0A126VC85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

61652:I6G83 RS10590
gene id: 61652:I6G83_RS10590
uniprot id: A0A140F150
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

61652:I6G83 RS10700
gene id: 61652:I6G83_RS10700
uniprot id: A0A4U9H9P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

61652:I6G83 RS16440
gene id: 61652:I6G83_RS16440
uniprot id: A0A447QT07
names: Similarity
messages: Belongs to the class A bacterial acid phosphatase family.

61652:I6G83 RS17975
gene id: 61652:I6G83_RS17975
uniprot id: A0A3S5F2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS03045
gene id: 61652:I6G83_RS03045
uniprot id: A0A4U9HSU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS00285
gene id: 61652:I6G83_RS00285
uniprot id: A0A447QGK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

61652:I6G83 RS09285
gene id: 61652:I6G83_RS09285
uniprot id: A0A3S5F176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

61652:I6G83 RS08610
gene id: 61652:I6G83_RS08610
uniprot id: A0A3S5F192
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

61652:I6G83 RS15765
gene id: 61652:I6G83_RS15765
uniprot id: A0A3S4JV29
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS19865
gene id: 61652:I6G83_RS19865
uniprot id: A0A126VJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

61652:I6G83 RS22095
gene id: 61652:I6G83_RS22095
uniprot id: A0A4U9HKH8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

61652:I6G83 RS20390
gene id: 61652:I6G83_RS20390
uniprot id: A0A4U9HMX3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS05140
gene id: 61652:I6G83_RS05140
uniprot id: A0A126VE87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

61652:I6G83 RS22550
gene id: 61652:I6G83_RS22550
uniprot id: A0A4U9HLA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS12910
gene id: 61652:I6G83_RS12910
uniprot id: A0A4U9HB12
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

61652:I6G83 RS17450
gene id: 61652:I6G83_RS17450
uniprot id: A0A126VKG5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

61652:I6G83 RS04360
gene id: 61652:I6G83_RS04360
uniprot id: A0A447QJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

61652:I6G83 RS00360
gene id: 61652:I6G83_RS00360
uniprot id: A0A126VIR2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

61652:I6G83 RS13550
gene id: 61652:I6G83_RS13550
uniprot id: A0A4U9HDH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS03750
gene id: 61652:I6G83_RS03750
uniprot id: A0A447QJD6
names: Subunit
messages: Monomer.

61652:I6G83 RS09385
gene id: 61652:I6G83_RS09385
uniprot id: A0A448S3P9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

61652:I6G83 RS01015
gene id: 61652:I6G83_RS01015
uniprot id: A0A126VGV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

61652:I6G83 RS10135
gene id: 61652:I6G83_RS10135
uniprot id: A0A448S370
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

61652:I6G83 RS16950
gene id: 61652:I6G83_RS16950
uniprot id: A0A126VKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

61652:I6G83 RS00410
gene id: 61652:I6G83_RS00410
uniprot id: A0A126VGV3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

61652:I6G83 RS14360
gene id: 61652:I6G83_RS14360
uniprot id: A0A4U9HGR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS08220
gene id: 61652:I6G83_RS08220
uniprot id: A0A4U9HA51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS08990
gene id: 61652:I6G83_RS08990
uniprot id: A0A447QN31
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

61652:I6G83 RS23440
gene id: 61652:I6G83_RS23440
uniprot id: A0A447QGF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

61652:I6G83 RS09330
gene id: 61652:I6G83_RS09330
uniprot id: A0A126VC15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

61652:I6G83 RS10055
gene id: 61652:I6G83_RS10055
uniprot id: A0A140F1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

61652:I6G83 RS00265
gene id: 61652:I6G83_RS00265
uniprot id: A0A448SHZ7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

61652:I6G83 RS03760
gene id: 61652:I6G83_RS03760
uniprot id: A0A4V6JI90
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

61652:I6G83 RS05855
gene id: 61652:I6G83_RS05855
uniprot id: A0A3S4FR02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61652:I6G83 RS01605
gene id: 61652:I6G83_RS01605
uniprot id: A0A3S5AU71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

61652:I6G83 RS06245
gene id: 61652:I6G83_RS06245
uniprot id: A0A126VDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

61652:I6G83 RS21180
gene id: 61652:I6G83_RS21180
uniprot id: A0A447QD36
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

61652:I6G83 RS06160
gene id: 61652:I6G83_RS06160
uniprot id: A0A126VFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

61652:I6G83 RS05160
gene id: 61652:I6G83_RS05160
uniprot id: A0A126VFH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

61652:I6G83 RS00670
gene id: 61652:I6G83_RS00670
uniprot id: A0A4U9HPL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

61652:I6G83 RS07220
gene id: 61652:I6G83_RS07220
uniprot id: A0A4V6JGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

61652:I6G83 RS15750
gene id: 61652:I6G83_RS15750
uniprot id: A0A126VL99
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

61652:I6G83 RS11535
gene id: 61652:I6G83_RS11535
uniprot id: A0A4U9HAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

61652:I6G83 RS14460
gene id: 61652:I6G83_RS14460
uniprot id: A0A126VLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

61652:I6G83 RS11425
gene id: 61652:I6G83_RS11425
uniprot id: A0A448S1L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

61652:I6G83 RS13265
gene id: 61652:I6G83_RS13265
uniprot id: A0A3S4GE79
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

61652:I6G83 RS16105
gene id: 61652:I6G83_RS16105
uniprot id: A0A2X5EQR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

61652:I6G83 RS13565
gene id: 61652:I6G83_RS13565
uniprot id: A0A140EZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LsrG family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).

61652:I6G83 RS01740
gene id: 61652:I6G83_RS01740
uniprot id: A0A126VFZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS05505
gene id: 61652:I6G83_RS05505
uniprot id: A0A2X5CBW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS06840
gene id: 61652:I6G83_RS06840
uniprot id: A0A126VDR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

61652:I6G83 RS11025
gene id: 61652:I6G83_RS11025
uniprot id: A0A2X5CFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

61652:I6G83 RS17480
gene id: 61652:I6G83_RS17480
uniprot id: A0A126VKF9
names: Similarity
messages: Belongs to the pyruvate kinase family.

61652:I6G83 RS14215
gene id: 61652:I6G83_RS14215
uniprot id: A0A3S5F109
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS10695
gene id: 61652:I6G83_RS10695
uniprot id: A0A3S5DFB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

61652:I6G83 RS01600
gene id: 61652:I6G83_RS01600
uniprot id: A0A448SFK9
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS10550
gene id: 61652:I6G83_RS10550
uniprot id: A0A4U9H9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

61652:I6G83 RS04700
gene id: 61652:I6G83_RS04700
uniprot id: A0A447QK06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

61652:I6G83 RS10485
gene id: 61652:I6G83_RS10485
uniprot id: A0A3S5DFB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS01195
gene id: 61652:I6G83_RS01195
uniprot id: A0A447QI29
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

61652:I6G83 RS05180
gene id: 61652:I6G83_RS05180
uniprot id: A0A2X5BVY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

61652:I6G83 RS11430
gene id: 61652:I6G83_RS11430
uniprot id: A0A140F0R5
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

61652:I6G83 RS14365
gene id: 61652:I6G83_RS14365
uniprot id: A0A447QRU8
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

61652:I6G83 RS21170
gene id: 61652:I6G83_RS21170
uniprot id: A0A4U9HJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

61652:I6G83 RS12615
gene id: 61652:I6G83_RS12615
uniprot id: A0A126VN05
names: Similarity
messages: Belongs to the UPF0250 family.

61652:I6G83 RS21240
gene id: 61652:I6G83_RS21240
uniprot id: A0A126VI64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

61652:I6G83 RS04865
gene id: 61652:I6G83_RS04865
uniprot id: A0A447QKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

61652:I6G83 RS06670
gene id: 61652:I6G83_RS06670
uniprot id: A0A447QM65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS04485
gene id: 61652:I6G83_RS04485
uniprot id: A0A448SB40
names: Similarity
messages: Belongs to the barstar family.

61652:I6G83 RS03875
gene id: 61652:I6G83_RS03875
uniprot id: A0A4U9HTY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

61652:I6G83 RS05445
gene id: 61652:I6G83_RS05445
uniprot id: A0A448S9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

61652:I6G83 RS10165
gene id: 61652:I6G83_RS10165
uniprot id: A0A4U9H9Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

61652:I6G83 RS19725
gene id: 61652:I6G83_RS19725
uniprot id: A0A126VJ73
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

61652:I6G83 RS04150
gene id: 61652:I6G83_RS04150
uniprot id: A0A447QJP7
names: Similarity
messages: Belongs to the pirin family.

61652:I6G83 RS11940
gene id: 61652:I6G83_RS11940
uniprot id: A0A140F0H8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

61652:I6G83 RS04900
gene id: 61652:I6G83_RS04900
uniprot id: A0A4U9HVS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS11910
gene id: 61652:I6G83_RS11910
uniprot id: A0A448S1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

61652:I6G83 RS19540
gene id: 61652:I6G83_RS19540
uniprot id: A0A3S4I5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

61652:I6G83 RS13480
gene id: 61652:I6G83_RS13480
uniprot id: A0A4U9HDU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

61652:I6G83 RS09355
gene id: 61652:I6G83_RS09355
uniprot id: A0A447QNC5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

61652:I6G83 RS08410
gene id: 61652:I6G83_RS08410
uniprot id: A0A448S4U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

61652:I6G83 RS02380
gene id: 61652:I6G83_RS02380
uniprot id: A0A3S4JPS3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS21030
gene id: 61652:I6G83_RS21030
uniprot id: A0A126VI90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

61652:I6G83 RS23045
gene id: 61652:I6G83_RS23045
uniprot id: A0A2X5B924
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

61652:I6G83 RS21140
gene id: 61652:I6G83_RS21140
uniprot id: A0A4U9HL97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

61652:I6G83 RS14635
gene id: 61652:I6G83_RS14635
uniprot id: A0A447QRU4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

61652:I6G83 RS16565
gene id: 61652:I6G83_RS16565
uniprot id: A0A448SUC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

61652:I6G83 RS11965
gene id: 61652:I6G83_RS11965
uniprot id: A0A140F0H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

61652:I6G83 RS11390
gene id: 61652:I6G83_RS11390
uniprot id: A0A4U9HA48
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

61652:I6G83 RS14835
gene id: 61652:I6G83_RS14835
uniprot id: A0A3S4JUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

61652:I6G83 RS00415
gene id: 61652:I6G83_RS00415
uniprot id: A0A4U9HP96
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

61652:I6G83 RS13295
gene id: 61652:I6G83_RS13295
uniprot id: A0A140EZT1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS15055
gene id: 61652:I6G83_RS15055
uniprot id: A0A126VLJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

61652:I6G83 RS10450
gene id: 61652:I6G83_RS10450
uniprot id: A0A4U9H9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

61652:I6G83 RS08955
gene id: 61652:I6G83_RS08955
uniprot id: A0A2X5BUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

61652:I6G83 RS07205
gene id: 61652:I6G83_RS07205
uniprot id: A0A447QLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

61652:I6G83 RS03795
gene id: 61652:I6G83_RS03795
uniprot id: A0A448SBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

61652:I6G83 RS12980
gene id: 61652:I6G83_RS12980
uniprot id: A0A4U9HBG9
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

61652:I6G83 RS07525
gene id: 61652:I6G83_RS07525
uniprot id: A0A4U9H7U7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS05290
gene id: 61652:I6G83_RS05290
uniprot id: A0A126VE27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

61652:I6G83 RS15320
gene id: 61652:I6G83_RS15320
uniprot id: A0A4U9HCF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS16210
gene id: 61652:I6G83_RS16210
uniprot id: A0A3S4JV96
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

61652:I6G83 RS01665
gene id: 61652:I6G83_RS01665
uniprot id: A0A126VHF1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS01550
gene id: 61652:I6G83_RS01550
uniprot id: A0A126VG47
names: Similarity
messages: Belongs to the UPF0253 family.

61652:I6G83 RS08725
gene id: 61652:I6G83_RS08725
uniprot id: A0A126VC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

61652:I6G83 RS02275
gene id: 61652:I6G83_RS02275
uniprot id: A0A4U9HVF8
names: Similarity
messages: Belongs to the UPF0149 family.

61652:I6G83 RS06620
gene id: 61652:I6G83_RS06620
uniprot id: A0A126VDG2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

61652:I6G83 RS02925
gene id: 61652:I6G83_RS02925
uniprot id: A0A447QJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

61652:I6G83 RS18705
gene id: 61652:I6G83_RS18705
uniprot id: A0A4U9HIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

61652:I6G83 RS08845
gene id: 61652:I6G83_RS08845
uniprot id: A0A4U9H8X9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

61652:I6G83 RS14680
gene id: 61652:I6G83_RS14680
uniprot id: A0A447QRZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61652:I6G83 RS02015
gene id: 61652:I6G83_RS02015
uniprot id: A0A4U9HQ67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS21385
gene id: 61652:I6G83_RS21385
uniprot id: A0A4U9HM12
names: Similarity
messages: Belongs to the ClpA/ClpB family.

61652:I6G83 RS18430
gene id: 61652:I6G83_RS18430
uniprot id: A0A3S4FW32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS02315
gene id: 61652:I6G83_RS02315
uniprot id: A0A447QJ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

61652:I6G83 RS07505
gene id: 61652:I6G83_RS07505
uniprot id: A0A4U9H871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

61652:I6G83 RS09840
gene id: 61652:I6G83_RS09840
uniprot id: A0A4U9HBQ5
names: Similarity
messages: Belongs to the histone deacetylase family.

61652:I6G83 RS09320
gene id: 61652:I6G83_RS09320
uniprot id: A0A448S3F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

61652:I6G83 RS00145
gene id: 61652:I6G83_RS00145
uniprot id: A0A3S5AVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61652:I6G83 RS09055
gene id: 61652:I6G83_RS09055
uniprot id: A0A447QMV3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

61652:I6G83 RS03680
gene id: 61652:I6G83_RS03680
uniprot id: A0A3S4GAN6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS10670
gene id: 61652:I6G83_RS10670
uniprot id: A0A4U9H9W0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS07070
gene id: 61652:I6G83_RS07070
uniprot id: A0A126VD39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

61652:I6G83 RS13700
gene id: 61652:I6G83_RS13700
uniprot id: A0A3S4H8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

61652:I6G83 RS10715
gene id: 61652:I6G83_RS10715
uniprot id: A0A4U9HA96
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

61652:I6G83 RS18250
gene id: 61652:I6G83_RS18250
uniprot id: A0A4U9HFP5
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS18595
gene id: 61652:I6G83_RS18595
uniprot id: A0A4U9HFT0
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

61652:I6G83 RS01595
gene id: 61652:I6G83_RS01595
uniprot id: A0A448SFA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

61652:I6G83 RS02665
gene id: 61652:I6G83_RS02665
uniprot id: A0A4U9HSB8
names: Similarity
messages: Belongs to the fabD family.

61652:I6G83 RS05055
gene id: 61652:I6G83_RS05055
uniprot id: A0A3S4YN97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

61652:I6G83 RS07740
gene id: 61652:I6G83_RS07740
uniprot id: A0A4U9H874
names: Function
messages: Required for maximal bacterial cellulose synthesis.

61652:I6G83 RS08265
gene id: 61652:I6G83_RS08265
uniprot id: A0A448S4V9
names: Similarity
messages: Belongs to the IMPACT family.

61652:I6G83 RS08155
gene id: 61652:I6G83_RS08155
uniprot id: A0A3S4GK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

61652:I6G83 RS09855
gene id: 61652:I6G83_RS09855
uniprot id: A0A4U9HDN0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

61652:I6G83 RS08350
gene id: 61652:I6G83_RS08350
uniprot id: A0A126VCG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS23430
gene id: 61652:I6G83_RS23430
uniprot id: A0A3S4WYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS15730
gene id: 61652:I6G83_RS15730
uniprot id: A0A3S4WRE4
names: Similarity
messages: Belongs to the PhoH family.

61652:I6G83 RS05555
gene id: 61652:I6G83_RS05555
uniprot id: A0A4V6JIW6
names: Similarity
messages: Belongs to the HSP15 family.

61652:I6G83 RS10410
gene id: 61652:I6G83_RS10410
uniprot id: A0A4U9H9W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

61652:I6G83 RS11360
gene id: 61652:I6G83_RS11360
uniprot id: A0A4V6JGL3
names: Subunit
messages: Monomer.

61652:I6G83 RS08195
gene id: 61652:I6G83_RS08195
uniprot id: A0A448S539
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

61652:I6G83 RS20030
gene id: 61652:I6G83_RS20030
uniprot id: A0A126VJ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

61652:I6G83 RS15260
gene id: 61652:I6G83_RS15260
uniprot id: A0A126VLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

61652:I6G83 RS15385
gene id: 61652:I6G83_RS15385
uniprot id: A0A4U9HF00
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61652:I6G83 RS07285
gene id: 61652:I6G83_RS07285
uniprot id: A0A447QMC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

61652:I6G83 RS11820
gene id: 61652:I6G83_RS11820
uniprot id: A0A4U9HCW6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

61652:I6G83 RS00945
gene id: 61652:I6G83_RS00945
uniprot id: A0A448SGH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS22330
gene id: 61652:I6G83_RS22330
uniprot id: A0A447QEG7
names: Similarity
messages: Belongs to the UPF0265 family.

61652:I6G83 RS00955
gene id: 61652:I6G83_RS00955
uniprot id: A0A3S4X6S4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RodZ family.
messages: Cell inner membrane
messages: Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
messages: The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.

61652:I6G83 RS00640
gene id: 61652:I6G83_RS00640
uniprot id: A0A448SH84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

61652:I6G83 RS15845
gene id: 61652:I6G83_RS15845
uniprot id: A0A3S4X3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

61652:I6G83 RS19990
gene id: 61652:I6G83_RS19990
uniprot id: A0A126VJ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

61652:I6G83 RS05035
gene id: 61652:I6G83_RS05035
uniprot id: A0A3S5F1J5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

61652:I6G83 RS06165
gene id: 61652:I6G83_RS06165
uniprot id: A0A448S8H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS02800
gene id: 61652:I6G83_RS02800
uniprot id: A0A126VG75
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

61652:I6G83 RS20615
gene id: 61652:I6G83_RS20615
uniprot id: A0A3S4I6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

61652:I6G83 RS21570
gene id: 61652:I6G83_RS21570
uniprot id: A0A4U9HJW7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

61652:I6G83 RS12095
gene id: 61652:I6G83_RS12095
uniprot id: A0A140F0E9
names: Similarity
messages: Belongs to the BolA/IbaG family.

61652:I6G83 RS20900
gene id: 61652:I6G83_RS20900
uniprot id: A0A4U9HNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS10710
gene id: 61652:I6G83_RS10710
uniprot id: A0A2X5BQZ8
names: Similarity
messages: Belongs to the CdaR family.

61652:I6G83 RS08630
gene id: 61652:I6G83_RS08630
uniprot id: A0A126VCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

61652:I6G83 RS04625
gene id: 61652:I6G83_RS04625
uniprot id: A0A126VEF8
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS03495
gene id: 61652:I6G83_RS03495
uniprot id: A0A4U9HRZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS15960
gene id: 61652:I6G83_RS15960
uniprot id: A0A4U9HD65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

61652:I6G83 RS11105
gene id: 61652:I6G83_RS11105
uniprot id: A0A4U9H9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

61652:I6G83 RS10160
gene id: 61652:I6G83_RS10160
uniprot id: A0A3S5F161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

61652:I6G83 RS18840
gene id: 61652:I6G83_RS18840
uniprot id: A0A4U9HG39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS01955
gene id: 61652:I6G83_RS01955
uniprot id: A0A3S4Y075
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS08160
gene id: 61652:I6G83_RS08160
uniprot id: A0A4U9H894
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

61652:I6G83 RS16785
gene id: 61652:I6G83_RS16785
uniprot id: A0A126VKQ0
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS14800
gene id: 61652:I6G83_RS14800
uniprot id: A0A4U9HH21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS17475
gene id: 61652:I6G83_RS17475
uniprot id: A0A2X5BR34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

61652:I6G83 RS07830
gene id: 61652:I6G83_RS07830
uniprot id: A0A126VCZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

61652:I6G83 RS23240
gene id: 61652:I6G83_RS23240
uniprot id: A0A126VH58
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS18580
gene id: 61652:I6G83_RS18580
uniprot id: A0A3S4I5J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

61652:I6G83 RS19180
gene id: 61652:I6G83_RS19180
uniprot id: A0A126VJH5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

61652:I6G83 RS02280
gene id: 61652:I6G83_RS02280
uniprot id: A0A2X5DNM9
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

61652:I6G83 RS22495
gene id: 61652:I6G83_RS22495
uniprot id: A0A126VHJ7
names: Similarity
messages: Belongs to the elongation factor P family.

61652:I6G83 RS21560
gene id: 61652:I6G83_RS21560
uniprot id: A0A4U9HKG7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

61652:I6G83 RS03730
gene id: 61652:I6G83_RS03730
uniprot id: A0A126VFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS07465
gene id: 61652:I6G83_RS07465
uniprot id: A0A4U9H863
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS17015
gene id: 61652:I6G83_RS17015
uniprot id: A0A448SU08
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

61652:I6G83 RS10600
gene id: 61652:I6G83_RS10600
uniprot id: A0A447QPA3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

61652:I6G83 RS05085
gene id: 61652:I6G83_RS05085
uniprot id: A0A2X5FHE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

61652:I6G83 RS07240
gene id: 61652:I6G83_RS07240
uniprot id: A0A4U9H7X8
names: Similarity
messages: Belongs to the VgrG protein family.

61652:I6G83 RS04230
gene id: 61652:I6G83_RS04230
uniprot id: A0A126VF06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

61652:I6G83 RS07895
gene id: 61652:I6G83_RS07895
uniprot id: A0A447QMF3
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

61652:I6G83 RS05485
gene id: 61652:I6G83_RS05485
uniprot id: A0A126VE44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

61652:I6G83 RS09395
gene id: 61652:I6G83_RS09395
uniprot id: A0A126VCS0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.

61652:I6G83 RS11870
gene id: 61652:I6G83_RS11870
uniprot id: A0A4U9HCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

61652:I6G83 RS10170
gene id: 61652:I6G83_RS10170
uniprot id: A0A140F1E0
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS11780
gene id: 61652:I6G83_RS11780
uniprot id: A0A140F0K7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS20625
gene id: 61652:I6G83_RS20625
uniprot id: A0A447QVV0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

61652:I6G83 RS07775
gene id: 61652:I6G83_RS07775
uniprot id: A0A3S4FSR9
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

61652:I6G83 RS01820
gene id: 61652:I6G83_RS01820
uniprot id: A0A4U9HSA3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

61652:I6G83 RS07750
gene id: 61652:I6G83_RS07750
uniprot id: A0A4U9HC90
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS05285
gene id: 61652:I6G83_RS05285
uniprot id: A0A447QKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

61652:I6G83 RS18670
gene id: 61652:I6G83_RS18670
uniprot id: A0A4U9HIA9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61652:I6G83 RS14495
gene id: 61652:I6G83_RS14495
uniprot id: A0A4U9HCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS01625
gene id: 61652:I6G83_RS01625
uniprot id: A0A448SF92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

61652:I6G83 RS12625
gene id: 61652:I6G83_RS12625
uniprot id: A0A4U9HBF0
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

61652:I6G83 RS10240
gene id: 61652:I6G83_RS10240
uniprot id: A0A140F1C9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

61652:I6G83 RS13515
gene id: 61652:I6G83_RS13515
uniprot id: A0A140EZP0
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS11680
gene id: 61652:I6G83_RS11680
uniprot id: A0A4U9HAC2
names: Similarity
messages: Belongs to the YkuD family.

61652:I6G83 RS19925
gene id: 61652:I6G83_RS19925
uniprot id: A0A447QVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

61652:I6G83 RS17800
gene id: 61652:I6G83_RS17800
uniprot id: A0A4U9HF44
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

61652:I6G83 RS02840
gene id: 61652:I6G83_RS02840
uniprot id: A0A126VFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

61652:I6G83 RS08250
gene id: 61652:I6G83_RS08250
uniprot id: A0A3S4WD66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

61652:I6G83 RS04690
gene id: 61652:I6G83_RS04690
uniprot id: A0A4U9HVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

61652:I6G83 RS04470
gene id: 61652:I6G83_RS04470
uniprot id: A0A126VFE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

61652:I6G83 RS20225
gene id: 61652:I6G83_RS20225
uniprot id: A0A126VKC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

61652:I6G83 RS13645
gene id: 61652:I6G83_RS13645
uniprot id: A0A140EZL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS06000
gene id: 61652:I6G83_RS06000
uniprot id: A0A3S5AQK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS04340
gene id: 61652:I6G83_RS04340
uniprot id: A0A4U9HV41
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS22935
gene id: 61652:I6G83_RS22935
uniprot id: A0A4U9HLU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

61652:I6G83 RS16730
gene id: 61652:I6G83_RS16730
uniprot id: A0A3S5F2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

61652:I6G83 RS12725
gene id: 61652:I6G83_RS12725
uniprot id: A0A4U9HBG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

61652:I6G83 RS10265
gene id: 61652:I6G83_RS10265
uniprot id: A0A448S2Q0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

61652:I6G83 RS01420
gene id: 61652:I6G83_RS01420
uniprot id: A0A447QI08
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

61652:I6G83 RS14480
gene id: 61652:I6G83_RS14480
uniprot id: A0A4U9HCH9
names: Similarity
messages: Belongs to the UPF0053 family.

61652:I6G83 RS09145
gene id: 61652:I6G83_RS09145
uniprot id: A0A4U9HD60
names: Similarity
messages: Belongs to the UPF0213 family.

61652:I6G83 RS07755
gene id: 61652:I6G83_RS07755
uniprot id: A0A4U9H7Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

61652:I6G83 RS06800
gene id: 61652:I6G83_RS06800
uniprot id: A0A126VE58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

61652:I6G83 RS06920
gene id: 61652:I6G83_RS06920
uniprot id: A0A447QLV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS19255
gene id: 61652:I6G83_RS19255
uniprot id: A0A4U9HGL8
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

61652:I6G83 RS17000
gene id: 61652:I6G83_RS17000
uniprot id: A0A126VKK0
names: Similarity
messages: Belongs to the peptidase C40 family.

61652:I6G83 RS06945
gene id: 61652:I6G83_RS06945
uniprot id: A0A447QLU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS07780
gene id: 61652:I6G83_RS07780
uniprot id: A0A3S4GK22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

61652:I6G83 RS06595
gene id: 61652:I6G83_RS06595
uniprot id: A0A126VDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

61652:I6G83 RS21095
gene id: 61652:I6G83_RS21095
uniprot id: A0A447QCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

61652:I6G83 RS21035
gene id: 61652:I6G83_RS21035
uniprot id: A0A447QCW2
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS09360
gene id: 61652:I6G83_RS09360
uniprot id: A0A126VC26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

61652:I6G83 RS11365
gene id: 61652:I6G83_RS11365
uniprot id: A0A4U9HAP2
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS16370
gene id: 61652:I6G83_RS16370
uniprot id: A0A126VKX7
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS02595
gene id: 61652:I6G83_RS02595
uniprot id: A0A126VFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

61652:I6G83 RS15115
gene id: 61652:I6G83_RS15115
uniprot id: A0A4U9HEU7
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS22655
gene id: 61652:I6G83_RS22655
uniprot id: A0A4U9HL56
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

61652:I6G83 RS09650
gene id: 61652:I6G83_RS09650
uniprot id: A0A4U9H9C0
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

61652:I6G83 RS13125
gene id: 61652:I6G83_RS13125
uniprot id: A0A140EZW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

61652:I6G83 RS22645
gene id: 61652:I6G83_RS22645
uniprot id: A0A447QFB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS18590
gene id: 61652:I6G83_RS18590
uniprot id: A0A4U9HFT2
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

61652:I6G83 RS18965
gene id: 61652:I6G83_RS18965
uniprot id: A0A4U9HG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

61652:I6G83 RS17740
gene id: 61652:I6G83_RS17740
uniprot id: A0A448ST64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

61652:I6G83 RS10640
gene id: 61652:I6G83_RS10640
uniprot id: A0A140F141
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

61652:I6G83 RS08890
gene id: 61652:I6G83_RS08890
uniprot id: A0A126VCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

61652:I6G83 RS11980
gene id: 61652:I6G83_RS11980
uniprot id: A0A140F0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

61652:I6G83 RS11915
gene id: 61652:I6G83_RS11915
uniprot id: A0A448S1J3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS12440
gene id: 61652:I6G83_RS12440
uniprot id: A0A447QQI7
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS08070
gene id: 61652:I6G83_RS08070
uniprot id: A0A4U9H8J0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

61652:I6G83 RS15805
gene id: 61652:I6G83_RS15805
uniprot id: A0A126VL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

61652:I6G83 RS22425
gene id: 61652:I6G83_RS22425
uniprot id: A0A126VHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61652:I6G83 RS23200
gene id: 61652:I6G83_RS23200
uniprot id: A0A4U9HPF3
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

61652:I6G83 RS22055
gene id: 61652:I6G83_RS22055
uniprot id: A0A4U9HKP0
names: Similarity
messages: Belongs to the pyruvate kinase family.

61652:I6G83 RS00440
gene id: 61652:I6G83_RS00440
uniprot id: A0A4U9HSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

61652:I6G83 RS18895
gene id: 61652:I6G83_RS18895
uniprot id: A0A447QUT8
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

61652:I6G83 RS05900
gene id: 61652:I6G83_RS05900
uniprot id: A0A447QKQ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

61652:I6G83 RS10045
gene id: 61652:I6G83_RS10045
uniprot id: A0A4U9H9P7
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

61652:I6G83 RS21205
gene id: 61652:I6G83_RS21205
uniprot id: A0A447QCX6
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

61652:I6G83 RS14710
gene id: 61652:I6G83_RS14710
uniprot id: A0A4U9HGZ9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS19370
gene id: 61652:I6G83_RS19370
uniprot id: A0A4U9HHC5
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS20245
gene id: 61652:I6G83_RS20245
uniprot id: A0A4U9HK31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

61652:I6G83 RS05185
gene id: 61652:I6G83_RS05185
uniprot id: A0A447QKN9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

61652:I6G83 RS19410
gene id: 61652:I6G83_RS19410
uniprot id: A0A126VJJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS11620
gene id: 61652:I6G83_RS11620
uniprot id: A0A140F0N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

61652:I6G83 RS05175
gene id: 61652:I6G83_RS05175
uniprot id: A0A126VE26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

61652:I6G83 RS10960
gene id: 61652:I6G83_RS10960
uniprot id: A0A447QPI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

61652:I6G83 RS22465
gene id: 61652:I6G83_RS22465
uniprot id: A0A4U9HL54
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

61652:I6G83 RS06995
gene id: 61652:I6G83_RS06995
uniprot id: A0A3S4GBY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

61652:I6G83 RS07035
gene id: 61652:I6G83_RS07035
uniprot id: A0A3S5DF71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

61652:I6G83 RS15340
gene id: 61652:I6G83_RS15340
uniprot id: A0A448SWM7
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS21785
gene id: 61652:I6G83_RS21785
uniprot id: A0A4U9HMH3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

61652:I6G83 RS19655
gene id: 61652:I6G83_RS19655
uniprot id: A0A447QVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

61652:I6G83 RS04640
gene id: 61652:I6G83_RS04640
uniprot id: A0A126VEG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

61652:I6G83 RS09090
gene id: 61652:I6G83_RS09090
uniprot id: A0A4U9H923
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

61652:I6G83 RS23410
gene id: 61652:I6G83_RS23410
uniprot id: A0A3S4FNH9
names: Similarity
messages: Belongs to the MlaA family.

61652:I6G83 RS10475
gene id: 61652:I6G83_RS10475
uniprot id: A0A4U9H9H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

61652:I6G83 RS17655
gene id: 61652:I6G83_RS17655
uniprot id: A0A4U9HFB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

61652:I6G83 RS22130
gene id: 61652:I6G83_RS22130
uniprot id: A0A4U9HL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS04955
gene id: 61652:I6G83_RS04955
uniprot id: A0A4U9HTT0
names: Cofactor
messages: Can also use Mn(2+) ion.

61652:I6G83 RS13475
gene id: 61652:I6G83_RS13475
uniprot id: A0A4U9HBT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS18155
gene id: 61652:I6G83_RS18155
uniprot id: A0A4U9HFL0
names: Similarity
messages: Belongs to the peptidase S11 family.

61652:I6G83 RS06170
gene id: 61652:I6G83_RS06170
uniprot id: A0A447QL06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

61652:I6G83 RS05190
gene id: 61652:I6G83_RS05190
uniprot id: A0A126VE82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

61652:I6G83 RS12800
gene id: 61652:I6G83_RS12800
uniprot id: A0A4U9HBH6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS03145
gene id: 61652:I6G83_RS03145
uniprot id: A0A4U9HSY0
names: Similarity
messages: Belongs to the UPF0276 family.

61652:I6G83 RS08395
gene id: 61652:I6G83_RS08395
uniprot id: A0A448S4T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

61652:I6G83 RS03775
gene id: 61652:I6G83_RS03775
uniprot id: A0A4U9HXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

61652:I6G83 RS12175
gene id: 61652:I6G83_RS12175
uniprot id: A0A140F0D5
names: Similarity
messages: Belongs to the P(II) protein family.

61652:I6G83 RS02650
gene id: 61652:I6G83_RS02650
uniprot id: A0A448SDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

61652:I6G83 RS11075
gene id: 61652:I6G83_RS11075
uniprot id: A0A140F0X3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

61652:I6G83 RS10525
gene id: 61652:I6G83_RS10525
uniprot id: A0A3S5AM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

61652:I6G83 RS08085
gene id: 61652:I6G83_RS08085
uniprot id: A0A126VCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

61652:I6G83 RS00530
gene id: 61652:I6G83_RS00530
uniprot id: A0A447QH50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

61652:I6G83 RS13450
gene id: 61652:I6G83_RS13450
uniprot id: A0A4U9HBC2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

61652:I6G83 RS05405
gene id: 61652:I6G83_RS05405
uniprot id: A0A4U9HZI6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS03655
gene id: 61652:I6G83_RS03655
uniprot id: A0A4U9HXA9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS02890
gene id: 61652:I6G83_RS02890
uniprot id: A0A126VFM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

61652:I6G83 RS10225
gene id: 61652:I6G83_RS10225
uniprot id: A0A4U9H9S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

61652:I6G83 RS05490
gene id: 61652:I6G83_RS05490
uniprot id: A0A126VFV0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

61652:I6G83 RS19615
gene id: 61652:I6G83_RS19615
uniprot id: A0A126VJ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS05475
gene id: 61652:I6G83_RS05475
uniprot id: A0A126VE74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS22445
gene id: 61652:I6G83_RS22445
uniprot id: A0A4U9HN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

61652:I6G83 RS16815
gene id: 61652:I6G83_RS16815
uniprot id: A0A3S4GNP1
names: Similarity
messages: Belongs to the fructosamine kinase family.

61652:I6G83 RS00030
gene id: 61652:I6G83_RS00030
uniprot id: A0A126VIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

61652:I6G83 RS06335
gene id: 61652:I6G83_RS06335
uniprot id: A0A126VED2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

61652:I6G83 RS15365
gene id: 61652:I6G83_RS15365
uniprot id: A0A126VLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

61652:I6G83 RS09050
gene id: 61652:I6G83_RS09050
uniprot id: A0A126VC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

61652:I6G83 RS01920
gene id: 61652:I6G83_RS01920
uniprot id: A0A4V6JI17
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

61652:I6G83 RS21730
gene id: 61652:I6G83_RS21730
uniprot id: A0A447QDB3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS05635
gene id: 61652:I6G83_RS05635
uniprot id: A0A126VDY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

61652:I6G83 RS08500
gene id: 61652:I6G83_RS08500
uniprot id: A0A448S4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS16505
gene id: 61652:I6G83_RS16505
uniprot id: A0A448SUS9
names: Similarity
messages: Belongs to the glutamine synthetase family.

61652:I6G83 RS12905
gene id: 61652:I6G83_RS12905
uniprot id: A0A4U9HFQ4
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

61652:I6G83 RS01750
gene id: 61652:I6G83_RS01750
uniprot id: A0A126VHX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS01050
gene id: 61652:I6G83_RS01050
uniprot id: A0A448SG93
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS14395
gene id: 61652:I6G83_RS14395
uniprot id: A0A447QRT4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

61652:I6G83 RS01415
gene id: 61652:I6G83_RS01415
uniprot id: A0A126VGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS01575
gene id: 61652:I6G83_RS01575
uniprot id: A0A3S4WIB7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

61652:I6G83 RS18520
gene id: 61652:I6G83_RS18520
uniprot id: A0A4U9HFR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

61652:I6G83 RS09270
gene id: 61652:I6G83_RS09270
uniprot id: A0A126VBY8
names: Similarity
messages: Belongs to the RutC family.

61652:I6G83 RS23165
gene id: 61652:I6G83_RS23165
uniprot id: A0A126VH46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

61652:I6G83 RS09945
gene id: 61652:I6G83_RS09945
uniprot id: A0A140F1H7
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
messages: Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion.

61652:I6G83 RS16610
gene id: 61652:I6G83_RS16610
uniprot id: A0A4V6JGX4
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

61652:I6G83 RS14270
gene id: 61652:I6G83_RS14270
uniprot id: A0A4U9HBV0
names: Similarity
messages: Belongs to the MQO family.

61652:I6G83 RS04565
gene id: 61652:I6G83_RS04565
uniprot id: A0A448SAW7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

61652:I6G83 RS12965
gene id: 61652:I6G83_RS12965
uniprot id: A0A448S0M9
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

61652:I6G83 RS11470
gene id: 61652:I6G83_RS11470
uniprot id: A0A4U9HAS0
names: Similarity
messages: Belongs to the IucA/IucC family.

61652:I6G83 RS23175
gene id: 61652:I6G83_RS23175
uniprot id: A0A447QFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

61652:I6G83 RS12485
gene id: 61652:I6G83_RS12485
uniprot id: A0A4U9HBC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

61652:I6G83 RS06230
gene id: 61652:I6G83_RS06230
uniprot id: A0A4U9HVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

61652:I6G83 RS20280
gene id: 61652:I6G83_RS20280
uniprot id: A0A4U9HID9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

61652:I6G83 RS02655
gene id: 61652:I6G83_RS02655
uniprot id: A0A126VFT5
names: Similarity
messages: Belongs to the UPF0231 family.

61652:I6G83 RS06610
gene id: 61652:I6G83_RS06610
uniprot id: A0A126VDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

61652:I6G83 RS09175
gene id: 61652:I6G83_RS09175
uniprot id: A0A447QN84
names: Caution
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS07785
gene id: 61652:I6G83_RS07785
uniprot id: A0A447QME9
names: Similarity
messages: Belongs to the thioredoxin family.

61652:I6G83 RS02535
gene id: 61652:I6G83_RS02535
uniprot id: A0A448SDN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

61652:I6G83 RS02850
gene id: 61652:I6G83_RS02850
uniprot id: A0A126VG65
names: Similarity
messages: Belongs to the UPF0235 family.

61652:I6G83 RS15850
gene id: 61652:I6G83_RS15850
uniprot id: A0A126VL80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

61652:I6G83 RS11865
gene id: 61652:I6G83_RS11865
uniprot id: A0A140F0J2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

61652:I6G83 RS21850
gene id: 61652:I6G83_RS21850
uniprot id: A0A4U9HMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

61652:I6G83 RS01835
gene id: 61652:I6G83_RS01835
uniprot id: A0A447QIE3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS00790
gene id: 61652:I6G83_RS00790
uniprot id: A0A447QH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

61652:I6G83 RS02855
gene id: 61652:I6G83_RS02855
uniprot id: A0A126VFC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

61652:I6G83 RS12695
gene id: 61652:I6G83_RS12695
uniprot id: A0A448S0Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS15925
gene id: 61652:I6G83_RS15925
uniprot id: A0A447QSW3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS22410
gene id: 61652:I6G83_RS22410
uniprot id: A0A4U9HLG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

61652:I6G83 RS15325
gene id: 61652:I6G83_RS15325
uniprot id: A0A3S4G0Y5
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

61652:I6G83 RS06125
gene id: 61652:I6G83_RS06125
uniprot id: A0A126VE42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS14935
gene id: 61652:I6G83_RS14935
uniprot id: A0A4U9HC80
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

61652:I6G83 RS08810
gene id: 61652:I6G83_RS08810
uniprot id: A0A126VCQ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

61652:I6G83 RS09375
gene id: 61652:I6G83_RS09375
uniprot id: A0A3S4FTC2
names: Similarity
messages: Belongs to the CcmL/EutN family.

61652:I6G83 RS04110
gene id: 61652:I6G83_RS04110
uniprot id: A0A448SBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

61652:I6G83 RS05235
gene id: 61652:I6G83_RS05235
uniprot id: A0A126VE36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

61652:I6G83 RS11285
gene id: 61652:I6G83_RS11285
uniprot id: A0A447QPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

61652:I6G83 RS17415
gene id: 61652:I6G83_RS17415
uniprot id: A0A3S4GNW8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

61652:I6G83 RS00310
gene id: 61652:I6G83_RS00310
uniprot id: A0A3S4X7D9
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

61652:I6G83 RS14655
gene id: 61652:I6G83_RS14655
uniprot id: A0A447QS16
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

61652:I6G83 RS02215
gene id: 61652:I6G83_RS02215
uniprot id: A0A4V6JI76
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS00325
gene id: 61652:I6G83_RS00325
uniprot id: A0A126VHJ5
names: Similarity
messages: Belongs to the UPF0178 family.

61652:I6G83 RS10050
gene id: 61652:I6G83_RS10050
uniprot id: A0A4U9H9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

61652:I6G83 RS21505
gene id: 61652:I6G83_RS21505
uniprot id: A0A3S4G7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

61652:I6G83 RS11590
gene id: 61652:I6G83_RS11590
uniprot id: A0A3S4I2K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

61652:I6G83 RS05435
gene id: 61652:I6G83_RS05435
uniprot id: A0A4V6JIH3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

61652:I6G83 RS01735
gene id: 61652:I6G83_RS01735
uniprot id: A0A4U9HPU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

61652:I6G83 RS06205
gene id: 61652:I6G83_RS06205
uniprot id: A0A2X5CEB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

61652:I6G83 RS06020
gene id: 61652:I6G83_RS06020
uniprot id: A0A126VDU4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

61652:I6G83 RS10575
gene id: 61652:I6G83_RS10575
uniprot id: A0A4U9H9J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

61652:I6G83 RS22800
gene id: 61652:I6G83_RS22800
uniprot id: A0A4U9HLL2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

61652:I6G83 RS21230
gene id: 61652:I6G83_RS21230
uniprot id: A0A447QD72
names: Similarity
messages: Belongs to the MotB family.

61652:I6G83 RS10215
gene id: 61652:I6G83_RS10215
uniprot id: A0A140F1D4
names: Similarity
messages: Belongs to the UPF0246 family.

61652:I6G83 RS03155
gene id: 61652:I6G83_RS03155
uniprot id: A0A4U9HWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

61652:I6G83 RS21190
gene id: 61652:I6G83_RS21190
uniprot id: A0A126VI74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

61652:I6G83 RS01635
gene id: 61652:I6G83_RS01635
uniprot id: A0A3S5DF04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

61652:I6G83 RS06050
gene id: 61652:I6G83_RS06050
uniprot id: A0A126VEH7
names: Similarity
messages: Belongs to the UPF0438 family.

61652:I6G83 RS05150
gene id: 61652:I6G83_RS05150
uniprot id: A0A126VE86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

61652:I6G83 RS05545
gene id: 61652:I6G83_RS05545
uniprot id: A0A4U9HZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS00980
gene id: 61652:I6G83_RS00980
uniprot id: A0A448SGB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

61652:I6G83 RS16385
gene id: 61652:I6G83_RS16385
uniprot id: A0A126VM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

61652:I6G83 RS10560
gene id: 61652:I6G83_RS10560
uniprot id: A0A4U9H9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

61652:I6G83 RS10250
gene id: 61652:I6G83_RS10250
uniprot id: A0A4U9HBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

61652:I6G83 RS00390
gene id: 61652:I6G83_RS00390
uniprot id: A0A448SHL0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

61652:I6G83 RS03280
gene id: 61652:I6G83_RS03280
uniprot id: A0A4U9HU48
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

61652:I6G83 RS20920
gene id: 61652:I6G83_RS20920
uniprot id: A0A3S5DEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS19965
gene id: 61652:I6G83_RS19965
uniprot id: A0A4U9HJY6
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

61652:I6G83 RS05760
gene id: 61652:I6G83_RS05760
uniprot id: A0A3S4JU86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

61652:I6G83 RS00405
gene id: 61652:I6G83_RS00405
uniprot id: A0A4U9HQB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudK subfamily.
messages: Homodimer.
messages: Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.

61652:I6G83 RS03420
gene id: 61652:I6G83_RS03420
uniprot id: A0A4V6JID7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

61652:I6G83 RS05810
gene id: 61652:I6G83_RS05810
uniprot id: A0A4U9HWI6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

61652:I6G83 RS13140
gene id: 61652:I6G83_RS13140
uniprot id: A0A4U9HDM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS02035
gene id: 61652:I6G83_RS02035
uniprot id: A0A4U9HQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

61652:I6G83 RS10750
gene id: 61652:I6G83_RS10750
uniprot id: A0A3S4X9R7
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS11710
gene id: 61652:I6G83_RS11710
uniprot id: A0A4U9HAX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiD family. UbiD-like/FDC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the reversible decarboxylation of aromatic carboxylic acids.
messages: Homodimer.

61652:I6G83 RS00735
gene id: 61652:I6G83_RS00735
uniprot id: A0A3S4WY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

61652:I6G83 RS16115
gene id: 61652:I6G83_RS16115
uniprot id: A0A3S4H9T7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

61652:I6G83 RS22570
gene id: 61652:I6G83_RS22570
uniprot id: A0A126VHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

61652:I6G83 RS10120
gene id: 61652:I6G83_RS10120
uniprot id: A0A140F1F0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

61652:I6G83 RS03885
gene id: 61652:I6G83_RS03885
uniprot id: A0A447QJJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

61652:I6G83 RS07025
gene id: 61652:I6G83_RS07025
uniprot id: A0A126VD51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

61652:I6G83 RS06850
gene id: 61652:I6G83_RS06850
uniprot id: A0A2X5FLA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

61652:I6G83 RS21930
gene id: 61652:I6G83_RS21930
uniprot id: A0A4U9HKL7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

61652:I6G83 RS16250
gene id: 61652:I6G83_RS16250
uniprot id: A0A448SV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

61652:I6G83 RS18420
gene id: 61652:I6G83_RS18420
uniprot id: A0A4U9HG73
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

61652:I6G83 RS10425
gene id: 61652:I6G83_RS10425
uniprot id: A0A3S5DFB5
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

61652:I6G83 RS06155
gene id: 61652:I6G83_RS06155
uniprot id: A0A447QL45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS10110
gene id: 61652:I6G83_RS10110
uniprot id: A0A3S4GD45
names: Similarity
messages: Belongs to the Smp family.

61652:I6G83 RS04220
gene id: 61652:I6G83_RS04220
uniprot id: A0A126VEN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

61652:I6G83 RS19085
gene id: 61652:I6G83_RS19085
uniprot id: A0A4U9HIR9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61652:I6G83 RS15315
gene id: 61652:I6G83_RS15315
uniprot id: A0A4U9HHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

61652:I6G83 RS08900
gene id: 61652:I6G83_RS08900
uniprot id: A0A3S4FS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

61652:I6G83 RS10895
gene id: 61652:I6G83_RS10895
uniprot id: A0A140F101
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS00525
gene id: 61652:I6G83_RS00525
uniprot id: A0A126VIN3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

61652:I6G83 RS04475
gene id: 61652:I6G83_RS04475
uniprot id: A0A448SB19
names: Similarity
messages: Belongs to the peptidase U62 family.

61652:I6G83 RS22870
gene id: 61652:I6G83_RS22870
uniprot id: A0A3S4X885
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

61652:I6G83 RS12830
gene id: 61652:I6G83_RS12830
uniprot id: A0A126VMW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS13335
gene id: 61652:I6G83_RS13335
uniprot id: A0A447QQY7
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS17440
gene id: 61652:I6G83_RS17440
uniprot id: A0A126VL19
names: Similarity
messages: Belongs to the HesB/IscA family.

61652:I6G83 RS02325
gene id: 61652:I6G83_RS02325
uniprot id: A0A126VHK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

61652:I6G83 RS17570
gene id: 61652:I6G83_RS17570
uniprot id: A0A448STE5
names: Similarity
messages: Belongs to the glyoxalase I family.

61652:I6G83 RS17885
gene id: 61652:I6G83_RS17885
uniprot id: A0A4U9HF89
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS13830
gene id: 61652:I6G83_RS13830
uniprot id: A0A448S0C1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

61652:I6G83 RS03520
gene id: 61652:I6G83_RS03520
uniprot id: A0A4U9HX51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

61652:I6G83 RS08355
gene id: 61652:I6G83_RS08355
uniprot id: A0A126VCM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

61652:I6G83 RS19790
gene id: 61652:I6G83_RS19790
uniprot id: A0A4U9HJJ8
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

61652:I6G83 RS18105
gene id: 61652:I6G83_RS18105
uniprot id: A0A4U9HFI9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

61652:I6G83 RS06365
gene id: 61652:I6G83_RS06365
uniprot id: A0A126VFE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

61652:I6G83 RS23160
gene id: 61652:I6G83_RS23160
uniprot id: A0A126VH64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS06030
gene id: 61652:I6G83_RS06030
uniprot id: A0A3S4FWW8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

61652:I6G83 RS08170
gene id: 61652:I6G83_RS08170
uniprot id: A0A126VCJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

61652:I6G83 RS17595
gene id: 61652:I6G83_RS17595
uniprot id: A0A3S4XNA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS21835
gene id: 61652:I6G83_RS21835
uniprot id: A0A4U9HLC1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS06040
gene id: 61652:I6G83_RS06040
uniprot id: A0A126VE48
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS05730
gene id: 61652:I6G83_RS05730
uniprot id: A0A126VFQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

61652:I6G83 RS09750
gene id: 61652:I6G83_RS09750
uniprot id: A0A4U9H9D6
names: Similarity
messages: Belongs to the glutamine synthetase family.

61652:I6G83 RS05410
gene id: 61652:I6G83_RS05410
uniprot id: A0A4V6JIH5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

61652:I6G83 RS12805
gene id: 61652:I6G83_RS12805
uniprot id: A0A447QQQ4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS20580
gene id: 61652:I6G83_RS20580
uniprot id: A0A126VIR4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

61652:I6G83 RS16990
gene id: 61652:I6G83_RS16990
uniprot id: A0A448STR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

61652:I6G83 RS13095
gene id: 61652:I6G83_RS13095
uniprot id: A0A4U9HBM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

61652:I6G83 RS03290
gene id: 61652:I6G83_RS03290
uniprot id: A0A4U9HT38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

61652:I6G83 RS12150
gene id: 61652:I6G83_RS12150
uniprot id: A0A3S4FTD4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

61652:I6G83 RS07185
gene id: 61652:I6G83_RS07185
uniprot id: A0A3S4H6N4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

61652:I6G83 RS05655
gene id: 61652:I6G83_RS05655
uniprot id: A0A447QLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

61652:I6G83 RS07645
gene id: 61652:I6G83_RS07645
uniprot id: A0A126VE94
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS13005
gene id: 61652:I6G83_RS13005
uniprot id: A0A140EZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

61652:I6G83 RS14615
gene id: 61652:I6G83_RS14615
uniprot id: A0A447QRW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

61652:I6G83 RS02830
gene id: 61652:I6G83_RS02830
uniprot id: A0A3S4GAE1
names: Similarity
messages: Belongs to the GSP E family.

61652:I6G83 RS18010
gene id: 61652:I6G83_RS18010
uniprot id: A0A3S4XMX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

61652:I6G83 RS10660
gene id: 61652:I6G83_RS10660
uniprot id: A0A4U9H9L6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

61652:I6G83 RS04460
gene id: 61652:I6G83_RS04460
uniprot id: A0A4U9HTI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS08205
gene id: 61652:I6G83_RS08205
uniprot id: A0A126VCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

61652:I6G83 RS10970
gene id: 61652:I6G83_RS10970
uniprot id: A0A4U9HAG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

61652:I6G83 RS19780
gene id: 61652:I6G83_RS19780
uniprot id: A0A126VJD2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

61652:I6G83 RS12195
gene id: 61652:I6G83_RS12195
uniprot id: A0A4U9HB72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS21110
gene id: 61652:I6G83_RS21110
uniprot id: A0A448SMF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

61652:I6G83 RS10580
gene id: 61652:I6G83_RS10580
uniprot id: A0A4U9HBN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

61652:I6G83 RS14450
gene id: 61652:I6G83_RS14450
uniprot id: A0A448SY23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

61652:I6G83 RS12645
gene id: 61652:I6G83_RS12645
uniprot id: A0A140F051
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

61652:I6G83 RS02590
gene id: 61652:I6G83_RS02590
uniprot id: A0A126VGB3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

61652:I6G83 RS11525
gene id: 61652:I6G83_RS11525
uniprot id: A0A140F0Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

61652:I6G83 RS05875
gene id: 61652:I6G83_RS05875
uniprot id: A0A3S4I0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

61652:I6G83 RS15175
gene id: 61652:I6G83_RS15175
uniprot id: A0A4U9HCP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

61652:I6G83 RS20955
gene id: 61652:I6G83_RS20955
uniprot id: A0A4U9HL10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

61652:I6G83 RS04745
gene id: 61652:I6G83_RS04745
uniprot id: A0A3S4WUK3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

61652:I6G83 RS02320
gene id: 61652:I6G83_RS02320
uniprot id: A0A126VFN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

61652:I6G83 RS04385
gene id: 61652:I6G83_RS04385
uniprot id: A0A126VEX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

61652:I6G83 RS06200
gene id: 61652:I6G83_RS06200
uniprot id: A0A126VDJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

61652:I6G83 RS16635
gene id: 61652:I6G83_RS16635
uniprot id: A0A4V6JGX7
names: Similarity
messages: Belongs to the PrpF family.

61652:I6G83 RS05660
gene id: 61652:I6G83_RS05660
uniprot id: A0A448S983
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

61652:I6G83 RS00430
gene id: 61652:I6G83_RS00430
uniprot id: A0A448SHI9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

61652:I6G83 RS08935
gene id: 61652:I6G83_RS08935
uniprot id: A0A126VC55
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

61652:I6G83 RS20395
gene id: 61652:I6G83_RS20395
uniprot id: A0A447QVU4
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS19065
gene id: 61652:I6G83_RS19065
uniprot id: A0A447QV10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS08315
gene id: 61652:I6G83_RS08315
uniprot id: A0A126VDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

61652:I6G83 RS23370
gene id: 61652:I6G83_RS23370
uniprot id: A0A448SI76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

61652:I6G83 RS22785
gene id: 61652:I6G83_RS22785
uniprot id: A0A4U9HLZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

61652:I6G83 RS08695
gene id: 61652:I6G83_RS08695
uniprot id: A0A4U9H8P7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS20670
gene id: 61652:I6G83_RS20670
uniprot id: A0A126VJ37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61652:I6G83 RS18915
gene id: 61652:I6G83_RS18915
uniprot id: A0A447QUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

61652:I6G83 RS18400
gene id: 61652:I6G83_RS18400
uniprot id: A0A3S4GP80
names: Subunit
messages: Monomer.

61652:I6G83 RS20970
gene id: 61652:I6G83_RS20970
uniprot id: A0A4U9HIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

61652:I6G83 RS01580
gene id: 61652:I6G83_RS01580
uniprot id: A0A448SFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

61652:I6G83 RS05535
gene id: 61652:I6G83_RS05535
uniprot id: A0A4U9HW75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

61652:I6G83 RS06330
gene id: 61652:I6G83_RS06330
uniprot id: A0A447QL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

61652:I6G83 RS01070
gene id: 61652:I6G83_RS01070
uniprot id: A0A3S5AMI9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS08565
gene id: 61652:I6G83_RS08565
uniprot id: A0A3S5AFR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

61652:I6G83 RS16400
gene id: 61652:I6G83_RS16400
uniprot id: A0A4U9HD22
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

61652:I6G83 RS17915
gene id: 61652:I6G83_RS17915
uniprot id: A0A447QU74
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

61652:I6G83 RS05040
gene id: 61652:I6G83_RS05040
uniprot id: A0A4U9HU90
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

61652:I6G83 RS12525
gene id: 61652:I6G83_RS12525
uniprot id: A0A140F074
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS10620
gene id: 61652:I6G83_RS10620
uniprot id: A0A448S2B2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61652:I6G83 RS08210
gene id: 61652:I6G83_RS08210
uniprot id: A0A4U9HCL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

61652:I6G83 RS06615
gene id: 61652:I6G83_RS06615
uniprot id: A0A126VFA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

61652:I6G83 RS23015
gene id: 61652:I6G83_RS23015
uniprot id: A0A126VH86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

61652:I6G83 RS08235
gene id: 61652:I6G83_RS08235
uniprot id: A0A126VCL1
names: Similarity
messages: Belongs to the peptidase S51 family.

61652:I6G83 RS01145
gene id: 61652:I6G83_RS01145
uniprot id: A0A4U9HNW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

61652:I6G83 RS11785
gene id: 61652:I6G83_RS11785
uniprot id: A0A4U9HEZ3
names: Similarity
messages: Belongs to the pirin family.

61652:I6G83 RS20945
gene id: 61652:I6G83_RS20945
uniprot id: A0A2X5BBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS09280
gene id: 61652:I6G83_RS09280
uniprot id: A0A3S4FY89
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

61652:I6G83 RS09340
gene id: 61652:I6G83_RS09340
uniprot id: A0A448S3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS16735
gene id: 61652:I6G83_RS16735
uniprot id: A0A126VL10
names: Similarity
messages: Belongs to the peptidase S41A family.

61652:I6G83 RS09275
gene id: 61652:I6G83_RS09275
uniprot id: A0A447QNA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

61652:I6G83 RS06790
gene id: 61652:I6G83_RS06790
uniprot id: A0A4U9HYK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

61652:I6G83 RS20025
gene id: 61652:I6G83_RS20025
uniprot id: A0A126VJ22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

61652:I6G83 RS04085
gene id: 61652:I6G83_RS04085
uniprot id: A0A4U9HT25
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

61652:I6G83 RS15160
gene id: 61652:I6G83_RS15160
uniprot id: A0A126VLH3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

61652:I6G83 RS06480
gene id: 61652:I6G83_RS06480
uniprot id: A0A126VEA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

61652:I6G83 RS13630
gene id: 61652:I6G83_RS13630
uniprot id: A0A4U9HBK8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61652:I6G83 RS13030
gene id: 61652:I6G83_RS13030
uniprot id: A0A140EZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

61652:I6G83 RS23115
gene id: 61652:I6G83_RS23115
uniprot id: A0A126VH55
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS16260
gene id: 61652:I6G83_RS16260
uniprot id: A0A126VL47
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

61652:I6G83 RS16830
gene id: 61652:I6G83_RS16830
uniprot id: A0A3S4G1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS07130
gene id: 61652:I6G83_RS07130
uniprot id: A0A126VD60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

61652:I6G83 RS18425
gene id: 61652:I6G83_RS18425
uniprot id: A0A4U9HI11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61652:I6G83 RS15090
gene id: 61652:I6G83_RS15090
uniprot id: A0A3S4JXR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

61652:I6G83 RS13270
gene id: 61652:I6G83_RS13270
uniprot id: A0A448S0I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

61652:I6G83 RS00650
gene id: 61652:I6G83_RS00650
uniprot id: A0A448SH64
names: Similarity
messages: Belongs to the heat shock protein 70 family.

61652:I6G83 RS11575
gene id: 61652:I6G83_RS11575
uniprot id: A0A4U9HCB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

61652:I6G83 RS19680
gene id: 61652:I6G83_RS19680
uniprot id: A0A4U9HH40
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS22300
gene id: 61652:I6G83_RS22300
uniprot id: A0A4U9HM04
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

61652:I6G83 RS01235
gene id: 61652:I6G83_RS01235
uniprot id: A0A4U9HP03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

61652:I6G83 RS14250
gene id: 61652:I6G83_RS14250
uniprot id: A0A3S4I3Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS07810
gene id: 61652:I6G83_RS07810
uniprot id: A0A4U9HAK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

61652:I6G83 RS04575
gene id: 61652:I6G83_RS04575
uniprot id: A0A447QK85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

61652:I6G83 RS08645
gene id: 61652:I6G83_RS08645
uniprot id: A0A4U9H8N6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

61652:I6G83 RS06150
gene id: 61652:I6G83_RS06150
uniprot id: A0A126VDM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

61652:I6G83 RS20780
gene id: 61652:I6G83_RS20780
uniprot id: A0A2X5BDR4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04265
gene id: 61652:I6G83_RS04265
uniprot id: A0A126VFI0
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

61652:I6G83 RS04760
gene id: 61652:I6G83_RS04760
uniprot id: A0A3S4YNH8
names: Similarity
messages: Belongs to the FGGY kinase family.

61652:I6G83 RS07925
gene id: 61652:I6G83_RS07925
uniprot id: A0A4U9HCD2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

61652:I6G83 RS02160
gene id: 61652:I6G83_RS02160
uniprot id: A0A126VG32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS20575
gene id: 61652:I6G83_RS20575
uniprot id: A0A3S4WZL8
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

61652:I6G83 RS21050
gene id: 61652:I6G83_RS21050
uniprot id: A0A3S4FN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

61652:I6G83 RS07090
gene id: 61652:I6G83_RS07090
uniprot id: A0A4U9H846
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS15030
gene id: 61652:I6G83_RS15030
uniprot id: A0A126VNJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

61652:I6G83 RS07685
gene id: 61652:I6G83_RS07685
uniprot id: A0A3S4I127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS04695
gene id: 61652:I6G83_RS04695
uniprot id: A0A4U9HTC7
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

61652:I6G83 RS05610
gene id: 61652:I6G83_RS05610
uniprot id: A0A4U9HUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

61652:I6G83 RS10470
gene id: 61652:I6G83_RS10470
uniprot id: A0A3S4WBR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

61652:I6G83 RS12635
gene id: 61652:I6G83_RS12635
uniprot id: A0A140F053
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

61652:I6G83 RS01455
gene id: 61652:I6G83_RS01455
uniprot id: A0A4U9HRU5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

61652:I6G83 RS06315
gene id: 61652:I6G83_RS06315
uniprot id: A0A3S4XCY9
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS04030
gene id: 61652:I6G83_RS04030
uniprot id: A0A447QJV4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61652:I6G83 RS20980
gene id: 61652:I6G83_RS20980
uniprot id: A0A126VIA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

61652:I6G83 RS14355
gene id: 61652:I6G83_RS14355
uniprot id: A0A140EZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS08820
gene id: 61652:I6G83_RS08820
uniprot id: A0A126VDL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

61652:I6G83 RS08730
gene id: 61652:I6G83_RS08730
uniprot id: A0A447QMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

61652:I6G83 RS00500
gene id: 61652:I6G83_RS00500
uniprot id: A0A3S4FQ49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

61652:I6G83 RS10400
gene id: 61652:I6G83_RS10400
uniprot id: A0A448S2E9
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

61652:I6G83 RS11010
gene id: 61652:I6G83_RS11010
uniprot id: A0A3S4WYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

61652:I6G83 RS02530
gene id: 61652:I6G83_RS02530
uniprot id: A0A126VFM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

61652:I6G83 RS05300
gene id: 61652:I6G83_RS05300
uniprot id: A0A4U9HUC2
names: Similarity
messages: Belongs to the NAPRTase family.

61652:I6G83 RS12135
gene id: 61652:I6G83_RS12135
uniprot id: A0A448S120
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

61652:I6G83 RS04810
gene id: 61652:I6G83_RS04810
uniprot id: A0A126VEE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

61652:I6G83 RS14110
gene id: 61652:I6G83_RS14110
uniprot id: A0A3S4JXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

61652:I6G83 RS12825
gene id: 61652:I6G83_RS12825
uniprot id: A0A4U9HD15
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

61652:I6G83 RS10725
gene id: 61652:I6G83_RS10725
uniprot id: A0A4U9HA39
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

61652:I6G83 RS01400
gene id: 61652:I6G83_RS01400
uniprot id: A0A447QHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

61652:I6G83 RS22725
gene id: 61652:I6G83_RS22725
uniprot id: A0A3S4WZF1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS00335
gene id: 61652:I6G83_RS00335
uniprot id: A0A447QGN4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS14670
gene id: 61652:I6G83_RS14670
uniprot id: A0A3S4JXJ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS10920
gene id: 61652:I6G83_RS10920
uniprot id: A0A4V6JGK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

61652:I6G83 RS06270
gene id: 61652:I6G83_RS06270
uniprot id: A0A3S4FS91
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

61652:I6G83 RS20230
gene id: 61652:I6G83_RS20230
uniprot id: A0A4U9HHR7
names: Similarity
messages: Belongs to the UPF0162 family.

61652:I6G83 RS15375
gene id: 61652:I6G83_RS15375
uniprot id: A0A4U9HD26
names: Similarity
messages: Belongs to the acylphosphatase family.

61652:I6G83 RS10455
gene id: 61652:I6G83_RS10455
uniprot id: A0A447QP61
names: Caution
names: Function
messages: Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS15380
gene id: 61652:I6G83_RS15380
uniprot id: A0A126VLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

61652:I6G83 RS07815
gene id: 61652:I6G83_RS07815
uniprot id: A0A4U9H893
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS22135
gene id: 61652:I6G83_RS22135
uniprot id: A0A4U9HMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS03925
gene id: 61652:I6G83_RS03925
uniprot id: A0A126VFA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

61652:I6G83 RS03840
gene id: 61652:I6G83_RS03840
uniprot id: A0A447QJF3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

61652:I6G83 RS20740
gene id: 61652:I6G83_RS20740
uniprot id: A0A126VIE2
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

61652:I6G83 RS17405
gene id: 61652:I6G83_RS17405
uniprot id: A0A447QTX4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

61652:I6G83 RS19470
gene id: 61652:I6G83_RS19470
uniprot id: A0A4U9HGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

61652:I6G83 RS02805
gene id: 61652:I6G83_RS02805
uniprot id: A0A4U9HR68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

61652:I6G83 RS19175
gene id: 61652:I6G83_RS19175
uniprot id: A0A447QV04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS19685
gene id: 61652:I6G83_RS19685
uniprot id: A0A4U9HH47
names: Similarity
messages: Belongs to the UPF0225 family.

61652:I6G83 RS15015
gene id: 61652:I6G83_RS15015
uniprot id: A0A126VLP8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

61652:I6G83 RS21150
gene id: 61652:I6G83_RS21150
uniprot id: A0A4U9HJX4
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

61652:I6G83 RS05735
gene id: 61652:I6G83_RS05735
uniprot id: A0A4V6YXZ1
names: Similarity
messages: Belongs to the TPP enzyme family.

61652:I6G83 RS11750
gene id: 61652:I6G83_RS11750
uniprot id: A0A4V6JGL9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

61652:I6G83 RS10685
gene id: 61652:I6G83_RS10685
uniprot id: A0A4U9HA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

61652:I6G83 RS22920
gene id: 61652:I6G83_RS22920
uniprot id: A0A4U9HM63
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

61652:I6G83 RS16020
gene id: 61652:I6G83_RS16020
uniprot id: A0A126VL44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

61652:I6G83 RS10490
gene id: 61652:I6G83_RS10490
uniprot id: A0A126VP53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

61652:I6G83 RS02455
gene id: 61652:I6G83_RS02455
uniprot id: A0A4U9HS20
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

61652:I6G83 RS08510
gene id: 61652:I6G83_RS08510
uniprot id: A0A447QMT7
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS12400
gene id: 61652:I6G83_RS12400
uniprot id: A0A140F094
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS06885
gene id: 61652:I6G83_RS06885
uniprot id: A0A126VDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

61652:I6G83 RS08975
gene id: 61652:I6G83_RS08975
uniprot id: A0A3S4FS45
names: Subcellular Location Annotation
messages: Cell inner membrane

61652:I6G83 RS14945
gene id: 61652:I6G83_RS14945
uniprot id: A0A4U9HCC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

61652:I6G83 RS05465
gene id: 61652:I6G83_RS05465
uniprot id: A0A4U9HUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

61652:I6G83 RS22770
gene id: 61652:I6G83_RS22770
uniprot id: A0A447QFG8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

61652:I6G83 RS16055
gene id: 61652:I6G83_RS16055
uniprot id: A0A4U9HHV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

61652:I6G83 RS02335
gene id: 61652:I6G83_RS02335
uniprot id: A0A3S4FVI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS15165
gene id: 61652:I6G83_RS15165
uniprot id: A0A448SWR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

61652:I6G83 RS08305
gene id: 61652:I6G83_RS08305
uniprot id: A0A4U9H8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

61652:I6G83 RS10655
gene id: 61652:I6G83_RS10655
uniprot id: A0A140F139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

61652:I6G83 RS20040
gene id: 61652:I6G83_RS20040
uniprot id: A0A4U9HHI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS00175
gene id: 61652:I6G83_RS00175
uniprot id: A0A4U9HNX0
names: Similarity
messages: Belongs to the TPP enzyme family.

61652:I6G83 RS01825
gene id: 61652:I6G83_RS01825
uniprot id: A0A4V6JI21
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS16280
gene id: 61652:I6G83_RS16280
uniprot id: A0A126VKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS08925
gene id: 61652:I6G83_RS08925
uniprot id: A0A126VD06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

61652:I6G83 RS08620
gene id: 61652:I6G83_RS08620
uniprot id: A0A2X5C1N4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

61652:I6G83 RS14985
gene id: 61652:I6G83_RS14985
uniprot id: A0A126VLM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

61652:I6G83 RS00965
gene id: 61652:I6G83_RS00965
uniprot id: A0A126VGJ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

61652:I6G83 RS19620
gene id: 61652:I6G83_RS19620
uniprot id: A0A3S5B019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS17990
gene id: 61652:I6G83_RS17990
uniprot id: A0A126VK72
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

61652:I6G83 RS15110
gene id: 61652:I6G83_RS15110
uniprot id: A0A4U9HCU1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS00275
gene id: 61652:I6G83_RS00275
uniprot id: A0A4V6JHV0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

61652:I6G83 RS17360
gene id: 61652:I6G83_RS17360
uniprot id: A0A4U9HGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

61652:I6G83 RS14275
gene id: 61652:I6G83_RS14275
uniprot id: A0A4U9HGQ1
names: Similarity
messages: Belongs to the GST superfamily.

61652:I6G83 RS09865
gene id: 61652:I6G83_RS09865
uniprot id: A0A3S4FSJ7
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04075
gene id: 61652:I6G83_RS04075
uniprot id: A0A4U9HT05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

61652:I6G83 RS21115
gene id: 61652:I6G83_RS21115
uniprot id: A0A448SMD3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

61652:I6G83 RS01850
gene id: 61652:I6G83_RS01850
uniprot id: A0A4V6JI14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

61652:I6G83 RS19995
gene id: 61652:I6G83_RS19995
uniprot id: A0A3S4XLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

61652:I6G83 RS08430
gene id: 61652:I6G83_RS08430
uniprot id: A0A126VCX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS03860
gene id: 61652:I6G83_RS03860
uniprot id: A0A448SBR0
names: Similarity
messages: Belongs to the UPF0441 family.

61652:I6G83 RS00930
gene id: 61652:I6G83_RS00930
uniprot id: A0A126VH98
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

61652:I6G83 RS13435
gene id: 61652:I6G83_RS13435
uniprot id: A0A4U9HBP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

61652:I6G83 RS10990
gene id: 61652:I6G83_RS10990
uniprot id: A0A4U9H9X2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

61652:I6G83 RS10880
gene id: 61652:I6G83_RS10880
uniprot id: A0A447QPH3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

61652:I6G83 RS04195
gene id: 61652:I6G83_RS04195
uniprot id: A0A448SBG2
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS02720
gene id: 61652:I6G83_RS02720
uniprot id: A0A126VFI7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

61652:I6G83 RS07955
gene id: 61652:I6G83_RS07955
uniprot id: A0A4U9H8C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

61652:I6G83 RS08745
gene id: 61652:I6G83_RS08745
uniprot id: A0A3S4WCU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

61652:I6G83 RS21045
gene id: 61652:I6G83_RS21045
uniprot id: A0A4U9HIW2
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

61652:I6G83 RS20940
gene id: 61652:I6G83_RS20940
uniprot id: A0A4U9HJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS15355
gene id: 61652:I6G83_RS15355
uniprot id: A0A3S4YZL8
names: Similarity
messages: Belongs to the UPF0319 family.

61652:I6G83 RS06340
gene id: 61652:I6G83_RS06340
uniprot id: A0A126VDG4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

61652:I6G83 RS10040
gene id: 61652:I6G83_RS10040
uniprot id: A0A4U9HBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

61652:I6G83 RS21725
gene id: 61652:I6G83_RS21725
uniprot id: A0A4U9HK26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

61652:I6G83 RS03460
gene id: 61652:I6G83_RS03460
uniprot id: A0A126VF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS10570
gene id: 61652:I6G83_RS10570
uniprot id: A0A140F154
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

61652:I6G83 RS17660
gene id: 61652:I6G83_RS17660
uniprot id: A0A3S4JYT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS17430
gene id: 61652:I6G83_RS17430
uniprot id: A0A447QTR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS07825
gene id: 61652:I6G83_RS07825
uniprot id: A0A4U9HCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

61652:I6G83 RS15210
gene id: 61652:I6G83_RS15210
uniprot id: A0A3S4GF17
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

61652:I6G83 RS04275
gene id: 61652:I6G83_RS04275
uniprot id: A0A126VEM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

61652:I6G83 RS13165
gene id: 61652:I6G83_RS13165
uniprot id: A0A140EZV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

61652:I6G83 RS12985
gene id: 61652:I6G83_RS12985
uniprot id: A0A140EZY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

61652:I6G83 RS12060
gene id: 61652:I6G83_RS12060
uniprot id: A0A2X5CAD9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

61652:I6G83 RS22395
gene id: 61652:I6G83_RS22395
uniprot id: A0A4U9HNC0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

61652:I6G83 RS12285
gene id: 61652:I6G83_RS12285
uniprot id: A0A4V6YXR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS19745
gene id: 61652:I6G83_RS19745
uniprot id: A0A448SPP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

61652:I6G83 RS14990
gene id: 61652:I6G83_RS14990
uniprot id: A0A4U9HCD8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

61652:I6G83 RS06430
gene id: 61652:I6G83_RS06430
uniprot id: A0A4U9HY69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

61652:I6G83 RS08385
gene id: 61652:I6G83_RS08385
uniprot id: A0A3S4GCG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

61652:I6G83 RS17515
gene id: 61652:I6G83_RS17515
uniprot id: A0A447QTZ4
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

61652:I6G83 RS17960
gene id: 61652:I6G83_RS17960
uniprot id: A0A126VK56
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

61652:I6G83 RS01645
gene id: 61652:I6G83_RS01645
uniprot id: A0A2X5A8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

61652:I6G83 RS03745
gene id: 61652:I6G83_RS03745
uniprot id: A0A447QJX5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

61652:I6G83 RS02860
gene id: 61652:I6G83_RS02860
uniprot id: A0A126VFC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

61652:I6G83 RS08190
gene id: 61652:I6G83_RS08190
uniprot id: A0A447QMN4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

61652:I6G83 RS15000
gene id: 61652:I6G83_RS15000
uniprot id: A0A4U9HCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

61652:I6G83 RS19650
gene id: 61652:I6G83_RS19650
uniprot id: A0A126VJ82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

61652:I6G83 RS15665
gene id: 61652:I6G83_RS15665
uniprot id: A0A3S4FVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS13290
gene id: 61652:I6G83_RS13290
uniprot id: A0A126VML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS02920
gene id: 61652:I6G83_RS02920
uniprot id: A0A4U9HSQ2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

61652:I6G83 RS14130
gene id: 61652:I6G83_RS14130
uniprot id: A0A140EZD3
names: Subcellular Location Annotation
messages: Cell outer membrane

61652:I6G83 RS07250
gene id: 61652:I6G83_RS07250
uniprot id: A0A4U9HBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family.
messages: Cell inner membrane
messages: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.

61652:I6G83 RS00225
gene id: 61652:I6G83_RS00225
uniprot id: A0A4U9HMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

61652:I6G83 RS01650
gene id: 61652:I6G83_RS01650
uniprot id: A0A3S4FPJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

61652:I6G83 RS20340
gene id: 61652:I6G83_RS20340
uniprot id: A0A4U9HMV8
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

61652:I6G83 RS06235
gene id: 61652:I6G83_RS06235
uniprot id: A0A447QL74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

61652:I6G83 RS06875
gene id: 61652:I6G83_RS06875
uniprot id: A0A126VDF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

61652:I6G83 RS12490
gene id: 61652:I6G83_RS12490
uniprot id: A0A3S5ADM9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

61652:I6G83 RS20150
gene id: 61652:I6G83_RS20150
uniprot id: A0A4U9HI97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

61652:I6G83 RS21965
gene id: 61652:I6G83_RS21965
uniprot id: A0A4U9HKD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS06590
gene id: 61652:I6G83_RS06590
uniprot id: A0A4U9I0V6
names: Similarity
messages: Belongs to the peptidase C59 family.

61652:I6G83 RS23080
gene id: 61652:I6G83_RS23080
uniprot id: A0A3S5AP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

61652:I6G83 RS10105
gene id: 61652:I6G83_RS10105
uniprot id: A0A3S4H7N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

61652:I6G83 RS13040
gene id: 61652:I6G83_RS13040
uniprot id: A0A2X5C6W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

61652:I6G83 RS23000
gene id: 61652:I6G83_RS23000
uniprot id: A0A126VHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

61652:I6G83 RS03920
gene id: 61652:I6G83_RS03920
uniprot id: A0A3S4XET7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS10865
gene id: 61652:I6G83_RS10865
uniprot id: A0A4U9HA74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

61652:I6G83 RS08910
gene id: 61652:I6G83_RS08910
uniprot id: A0A3S4H779
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

61652:I6G83 RS11935
gene id: 61652:I6G83_RS11935
uniprot id: A0A3S5F132
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

61652:I6G83 RS08230
gene id: 61652:I6G83_RS08230
uniprot id: A0A126VED9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

61652:I6G83 RS07985
gene id: 61652:I6G83_RS07985
uniprot id: A0A126VCP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

61652:I6G83 RS12590
gene id: 61652:I6G83_RS12590
uniprot id: A0A3S4JTR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

61652:I6G83 RS15150
gene id: 61652:I6G83_RS15150
uniprot id: A0A4U9HCH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

61652:I6G83 RS00950
gene id: 61652:I6G83_RS00950
uniprot id: A0A126VGG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

61652:I6G83 RS03010
gene id: 61652:I6G83_RS03010
uniprot id: A0A126VGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

61652:I6G83 RS14220
gene id: 61652:I6G83_RS14220
uniprot id: A0A4V6JGS0
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

61652:I6G83 RS06735
gene id: 61652:I6G83_RS06735
uniprot id: A0A4U9HW41
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

61652:I6G83 RS17550
gene id: 61652:I6G83_RS17550
uniprot id: A0A448STD1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

61652:I6G83 RS01250
gene id: 61652:I6G83_RS01250
uniprot id: A0A3S4JSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

61652:I6G83 RS03360
gene id: 61652:I6G83_RS03360
uniprot id: A0A4V6YXX9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

61652:I6G83 RS01630
gene id: 61652:I6G83_RS01630
uniprot id: A0A448SF91
names: Similarity
messages: Belongs to the skp family.

61652:I6G83 RS20010
gene id: 61652:I6G83_RS20010
uniprot id: A0A3S4X053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS18635
gene id: 61652:I6G83_RS18635
uniprot id: A0A4U9HFU9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS10760
gene id: 61652:I6G83_RS10760
uniprot id: A0A4U9HA49
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

61652:I6G83 RS03825
gene id: 61652:I6G83_RS03825
uniprot id: A0A447QK36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

61652:I6G83 RS12775
gene id: 61652:I6G83_RS12775
uniprot id: A0A447QQM1
names: Similarity
messages: Belongs to the asparagine synthetase family.

61652:I6G83 RS02105
gene id: 61652:I6G83_RS02105
uniprot id: A0A4U9HQA4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS09005
gene id: 61652:I6G83_RS09005
uniprot id: A0A447QN80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS00220
gene id: 61652:I6G83_RS00220
uniprot id: A0A4U9HNY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

61652:I6G83 RS19515
gene id: 61652:I6G83_RS19515
uniprot id: A0A126VJA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

61652:I6G83 RS22925
gene id: 61652:I6G83_RS22925
uniprot id: A0A126VHD0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS17750
gene id: 61652:I6G83_RS17750
uniprot id: A0A447QTY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

61652:I6G83 RS17855
gene id: 61652:I6G83_RS17855
uniprot id: A0A4V6JH24
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

61652:I6G83 RS23185
gene id: 61652:I6G83_RS23185
uniprot id: A0A4V6JII2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS02795
gene id: 61652:I6G83_RS02795
uniprot id: A0A447QIU8
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

61652:I6G83 RS14890
gene id: 61652:I6G83_RS14890
uniprot id: A0A126VLY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

61652:I6G83 RS12975
gene id: 61652:I6G83_RS12975
uniprot id: A0A4U9HBK7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

61652:I6G83 RS21075
gene id: 61652:I6G83_RS21075
uniprot id: A0A126VI72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

61652:I6G83 RS18675
gene id: 61652:I6G83_RS18675
uniprot id: A0A3S4GGB5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61652:I6G83 RS02115
gene id: 61652:I6G83_RS02115
uniprot id: A0A4U9HSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

61652:I6G83 RS03170
gene id: 61652:I6G83_RS03170
uniprot id: A0A4U9HSY7
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS06720
gene id: 61652:I6G83_RS06720
uniprot id: A0A4U9I106
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

61652:I6G83 RS22930
gene id: 61652:I6G83_RS22930
uniprot id: A0A4U9HLI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

61652:I6G83 RS11890
gene id: 61652:I6G83_RS11890
uniprot id: A0A140F0I7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

61652:I6G83 RS03105
gene id: 61652:I6G83_RS03105
uniprot id: A0A4U9HWL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS15240
gene id: 61652:I6G83_RS15240
uniprot id: A0A4U9HEJ6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

61652:I6G83 RS03210
gene id: 61652:I6G83_RS03210
uniprot id: A0A4U9HT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS01265
gene id: 61652:I6G83_RS01265
uniprot id: A0A126VG79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

61652:I6G83 RS18620
gene id: 61652:I6G83_RS18620
uniprot id: A0A3S4XCG6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

61652:I6G83 RS21585
gene id: 61652:I6G83_RS21585
uniprot id: A0A3S4Y3L9
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

61652:I6G83 RS22900
gene id: 61652:I6G83_RS22900
uniprot id: A0A447QFS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS08270
gene id: 61652:I6G83_RS08270
uniprot id: A0A3S5ANM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

61652:I6G83 RS00235
gene id: 61652:I6G83_RS00235
uniprot id: A0A126VGW6
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS10675
gene id: 61652:I6G83_RS10675
uniprot id: A0A4V6JGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Membrane
messages: Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.

61652:I6G83 RS00560
gene id: 61652:I6G83_RS00560
uniprot id: A0A4U9HNJ1
names: Similarity
messages: Belongs to the ArsC family.

61652:I6G83 RS23190
gene id: 61652:I6G83_RS23190
uniprot id: A0A2X5ALY9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS07535
gene id: 61652:I6G83_RS07535
uniprot id: A0A4U9H834
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS21515
gene id: 61652:I6G83_RS21515
uniprot id: A0A3S4WYQ4
names: Similarity
messages: Belongs to the MoaD family.

61652:I6G83 RS02250
gene id: 61652:I6G83_RS02250
uniprot id: A0A447QII4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

61652:I6G83 RS16015
gene id: 61652:I6G83_RS16015
uniprot id: A0A447QSZ2
names: Similarity
messages: Belongs to the YciI family.

61652:I6G83 RS16395
gene id: 61652:I6G83_RS16395
uniprot id: A0A4U9HI30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

61652:I6G83 RS16905
gene id: 61652:I6G83_RS16905
uniprot id: A0A2X5BRB4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

61652:I6G83 RS03450
gene id: 61652:I6G83_RS03450
uniprot id: A0A4U9HRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

61652:I6G83 RS11625
gene id: 61652:I6G83_RS11625
uniprot id: A0A3S4FZ93
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

61652:I6G83 RS01860
gene id: 61652:I6G83_RS01860
uniprot id: A0A126VFX5
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

61652:I6G83 RS04500
gene id: 61652:I6G83_RS04500
uniprot id: A0A4U9HVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeB.

61652:I6G83 RS04875
gene id: 61652:I6G83_RS04875
uniprot id: A0A447QKB2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61652:I6G83 RS17865
gene id: 61652:I6G83_RS17865
uniprot id: A0A3S4I598
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS05790
gene id: 61652:I6G83_RS05790
uniprot id: A0A4U9HUY8
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS16920
gene id: 61652:I6G83_RS16920
uniprot id: A0A4U9HG33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

61652:I6G83 RS02330
gene id: 61652:I6G83_RS02330
uniprot id: A0A126VG41
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61652:I6G83 RS00780
gene id: 61652:I6G83_RS00780
uniprot id: A0A4U9HPU4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS12115
gene id: 61652:I6G83_RS12115
uniprot id: A0A4U9HAY2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

61652:I6G83 RS14905
gene id: 61652:I6G83_RS14905
uniprot id: A0A3S4FVM2
names: Similarity
messages: Belongs to the UPF0145 family.

61652:I6G83 RS12630
gene id: 61652:I6G83_RS12630
uniprot id: A0A447QQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

61652:I6G83 RS05365
gene id: 61652:I6G83_RS05365
uniprot id: A0A448S9P5
names: Similarity
messages: Belongs to the phosphoribulokinase family.

61652:I6G83 RS04175
gene id: 61652:I6G83_RS04175
uniprot id: A0A3S4JQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS05360
gene id: 61652:I6G83_RS05360
uniprot id: A0A126VEI1
names: Similarity
messages: Belongs to the UPF0270 family.

61652:I6G83 RS15180
gene id: 61652:I6G83_RS15180
uniprot id: A0A447QS97
names: Similarity
messages: Belongs to the YkuD family.

61652:I6G83 RS19340
gene id: 61652:I6G83_RS19340
uniprot id: A0A126VKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

61652:I6G83 RS07335
gene id: 61652:I6G83_RS07335
uniprot id: A0A4U9H7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS02295
gene id: 61652:I6G83_RS02295
uniprot id: A0A126VGH0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

61652:I6G83 RS23340
gene id: 61652:I6G83_RS23340
uniprot id: A0A447QG72
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

61652:I6G83 RS05975
gene id: 61652:I6G83_RS05975
uniprot id: A0A4U9I094
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS21250
gene id: 61652:I6G83_RS21250
uniprot id: A0A126VJJ1
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

61652:I6G83 RS11270
gene id: 61652:I6G83_RS11270
uniprot id: A0A140F0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

61652:I6G83 RS04880
gene id: 61652:I6G83_RS04880
uniprot id: A0A3S4X3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

61652:I6G83 RS14030
gene id: 61652:I6G83_RS14030
uniprot id: A0A447QRL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS08950
gene id: 61652:I6G83_RS08950
uniprot id: A0A4U9H973
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

61652:I6G83 RS04210
gene id: 61652:I6G83_RS04210
uniprot id: A0A4U9HSS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

61652:I6G83 RS09040
gene id: 61652:I6G83_RS09040
uniprot id: A0A126VC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

61652:I6G83 RS06240
gene id: 61652:I6G83_RS06240
uniprot id: A0A448S8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

61652:I6G83 RS07965
gene id: 61652:I6G83_RS07965
uniprot id: A0A3S4X0Q2
names: Similarity
messages: Belongs to the Rht family.

61652:I6G83 RS11570
gene id: 61652:I6G83_RS11570
uniprot id: A0A4U9HA99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

61652:I6G83 RS10810
gene id: 61652:I6G83_RS10810
uniprot id: A0A140F117
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS09150
gene id: 61652:I6G83_RS09150
uniprot id: A0A4U9HAQ3
names: Similarity
messages: Belongs to the UPF0306 family.

61652:I6G83 RS07020
gene id: 61652:I6G83_RS07020
uniprot id: A0A3S4WSK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

61652:I6G83 RS19460
gene id: 61652:I6G83_RS19460
uniprot id: A0A126VJC4
names: Similarity
messages: Belongs to the peptidase S49 family.

61652:I6G83 RS23010
gene id: 61652:I6G83_RS23010
uniprot id: A0A126VHJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

61652:I6G83 RS11110
gene id: 61652:I6G83_RS11110
uniprot id: A0A140F0W7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

61652:I6G83 RS01465
gene id: 61652:I6G83_RS01465
uniprot id: A0A4U9HQS6
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS18170
gene id: 61652:I6G83_RS18170
uniprot id: A0A4V6JH55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

61652:I6G83 RS10355
gene id: 61652:I6G83_RS10355
uniprot id: A0A3S5F157
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

61652:I6G83 RS00520
gene id: 61652:I6G83_RS00520
uniprot id: A0A126VGP4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS12220
gene id: 61652:I6G83_RS12220
uniprot id: A0A4U9HAP0
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

61652:I6G83 RS02645
gene id: 61652:I6G83_RS02645
uniprot id: A0A4U9HQZ6
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

61652:I6G83 RS12080
gene id: 61652:I6G83_RS12080
uniprot id: A0A3S4XTS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

61652:I6G83 RS04495
gene id: 61652:I6G83_RS04495
uniprot id: A0A3S4YNQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS12990
gene id: 61652:I6G83_RS12990
uniprot id: A0A448S0L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

61652:I6G83 RS17460
gene id: 61652:I6G83_RS17460
uniprot id: A0A4U9HGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
messages: Cytoplasm
messages: Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine.

61652:I6G83 RS01655
gene id: 61652:I6G83_RS01655
uniprot id: A0A4U9HUN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

61652:I6G83 RS05995
gene id: 61652:I6G83_RS05995
uniprot id: A0A126VF09
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS12390
gene id: 61652:I6G83_RS12390
uniprot id: A0A4U9HD83
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

61652:I6G83 RS12675
gene id: 61652:I6G83_RS12675
uniprot id: A0A4U9HBF9
names: Similarity
messages: Belongs to the class A bacterial acid phosphatase family.

61652:I6G83 RS13325
gene id: 61652:I6G83_RS13325
uniprot id: A0A140EZS6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

61652:I6G83 RS11530
gene id: 61652:I6G83_RS11530
uniprot id: A0A4U9HCB1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

61652:I6G83 RS02880
gene id: 61652:I6G83_RS02880
uniprot id: A0A447QJ29
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

61652:I6G83 RS16075
gene id: 61652:I6G83_RS16075
uniprot id: A0A4V6JGW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

61652:I6G83 RS18165
gene id: 61652:I6G83_RS18165
uniprot id: A0A447QUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

61652:I6G83 RS16965
gene id: 61652:I6G83_RS16965
uniprot id: A0A126VKK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

61652:I6G83 RS19625
gene id: 61652:I6G83_RS19625
uniprot id: A0A448SPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

61652:I6G83 RS17665
gene id: 61652:I6G83_RS17665
uniprot id: A0A4U9HJL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

61652:I6G83 RS01055
gene id: 61652:I6G83_RS01055
uniprot id: A0A4U9HP92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS19080
gene id: 61652:I6G83_RS19080
uniprot id: A0A126VJR2
names: Similarity
messages: Belongs to the AHA1 family.

61652:I6G83 RS14620
gene id: 61652:I6G83_RS14620
uniprot id: A0A3S4I3V7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

61652:I6G83 RS14100
gene id: 61652:I6G83_RS14100
uniprot id: A0A3S5AD63
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

61652:I6G83 RS19220
gene id: 61652:I6G83_RS19220
uniprot id: A0A447QV15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

61652:I6G83 RS08665
gene id: 61652:I6G83_RS08665
uniprot id: A0A4U9H8H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

61652:I6G83 RS16895
gene id: 61652:I6G83_RS16895
uniprot id: A0A126VL74
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS13275
gene id: 61652:I6G83_RS13275
uniprot id: A0A3S4FUW1
names: Similarity
messages: Belongs to the MoaD family.

61652:I6G83 RS05915
gene id: 61652:I6G83_RS05915
uniprot id: A0A4U9I066
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

61652:I6G83 RS05645
gene id: 61652:I6G83_RS05645
uniprot id: A0A4U9HX86
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

61652:I6G83 RS03915
gene id: 61652:I6G83_RS03915
uniprot id: A0A447QK18
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

61652:I6G83 RS06455
gene id: 61652:I6G83_RS06455
uniprot id: A0A2X5BZ32
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

61652:I6G83 RS00565
gene id: 61652:I6G83_RS00565
uniprot id: A0A3S4WJ95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

61652:I6G83 RS04240
gene id: 61652:I6G83_RS04240
uniprot id: A0A4U9HUY7
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

61652:I6G83 RS20755
gene id: 61652:I6G83_RS20755
uniprot id: A0A448SN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS21025
gene id: 61652:I6G83_RS21025
uniprot id: A0A447QD62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

61652:I6G83 RS16245
gene id: 61652:I6G83_RS16245
uniprot id: A0A126VLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

61652:I6G83 RS20020
gene id: 61652:I6G83_RS20020
uniprot id: A0A4U9HJU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

61652:I6G83 RS19815
gene id: 61652:I6G83_RS19815
uniprot id: A0A447QVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS18270
gene id: 61652:I6G83_RS18270
uniprot id: A0A4V6JH45
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

61652:I6G83 RS01205
gene id: 61652:I6G83_RS01205
uniprot id: A0A4U9HPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

61652:I6G83 RS15350
gene id: 61652:I6G83_RS15350
uniprot id: A0A447QSF3
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

61652:I6G83 RS21120
gene id: 61652:I6G83_RS21120
uniprot id: A0A447QD84
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

61652:I6G83 RS13510
gene id: 61652:I6G83_RS13510
uniprot id: A0A447QR66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS16130
gene id: 61652:I6G83_RS16130
uniprot id: A0A126VL23
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

61652:I6G83 RS21085
gene id: 61652:I6G83_RS21085
uniprot id: A0A126VK60
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

61652:I6G83 RS02740
gene id: 61652:I6G83_RS02740
uniprot id: A0A4U9HR41
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS12140
gene id: 61652:I6G83_RS12140
uniprot id: A0A140F0E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

61652:I6G83 RS21450
gene id: 61652:I6G83_RS21450
uniprot id: A0A4U9HM40
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS02200
gene id: 61652:I6G83_RS02200
uniprot id: A0A4U9HQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

61652:I6G83 RS12180
gene id: 61652:I6G83_RS12180
uniprot id: A0A140F0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS23425
gene id: 61652:I6G83_RS23425
uniprot id: A0A3S4FPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

61652:I6G83 RS12185
gene id: 61652:I6G83_RS12185
uniprot id: A0A3S4WYB0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

61652:I6G83 RS10545
gene id: 61652:I6G83_RS10545
uniprot id: A0A448S2H2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS08110
gene id: 61652:I6G83_RS08110
uniprot id: A0A4U9H8R0
names: Similarity
messages: Belongs to the leucine-binding protein family.

61652:I6G83 RS07160
gene id: 61652:I6G83_RS07160
uniprot id: A0A4U9H7V5
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

61652:I6G83 RS21540
gene id: 61652:I6G83_RS21540
uniprot id: A0A4U9HM73
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

61652:I6G83 RS16720
gene id: 61652:I6G83_RS16720
uniprot id: A0A126VKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

61652:I6G83 RS02265
gene id: 61652:I6G83_RS02265
uniprot id: A0A4U9HRS8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

61652:I6G83 RS10380
gene id: 61652:I6G83_RS10380
uniprot id: A0A447QNW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

61652:I6G83 RS09195
gene id: 61652:I6G83_RS09195
uniprot id: A0A4U9H8R5
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

61652:I6G83 RS14780
gene id: 61652:I6G83_RS14780
uniprot id: A0A447QS17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

61652:I6G83 RS10650
gene id: 61652:I6G83_RS10650
uniprot id: A0A4U9H9N8
names: Similarity
messages: Belongs to the GSP E family.

61652:I6G83 RS12580
gene id: 61652:I6G83_RS12580
uniprot id: A0A4U9HBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS01505
gene id: 61652:I6G83_RS01505
uniprot id: A0A2X5AXM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS13220
gene id: 61652:I6G83_RS13220
uniprot id: A0A140EZU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

61652:I6G83 RS14845
gene id: 61652:I6G83_RS14845
uniprot id: A0A448SXB7
names: Subunit
messages: Monomer.

61652:I6G83 RS11990
gene id: 61652:I6G83_RS11990
uniprot id: A0A140F0G9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

61652:I6G83 RS01440
gene id: 61652:I6G83_RS01440
uniprot id: A0A3S4YR22
names: Similarity
messages: Belongs to the thioredoxin family.

61652:I6G83 RS22880
gene id: 61652:I6G83_RS22880
uniprot id: A0A126VHP5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

61652:I6G83 RS15040
gene id: 61652:I6G83_RS15040
uniprot id: A0A4U9HET2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS21645
gene id: 61652:I6G83_RS21645
uniprot id: A0A4U9HK61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

61652:I6G83 RS02300
gene id: 61652:I6G83_RS02300
uniprot id: A0A2X5A5K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

61652:I6G83 RS11950
gene id: 61652:I6G83_RS11950
uniprot id: A0A447QQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

61652:I6G83 RS09555
gene id: 61652:I6G83_RS09555
uniprot id: A0A447QNK1
names: Similarity
messages: Belongs to the GSP E family.

61652:I6G83 RS04595
gene id: 61652:I6G83_RS04595
uniprot id: A0A4U9HT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61652:I6G83 RS12310
gene id: 61652:I6G83_RS12310
uniprot id: A0A4U9HFA9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

61652:I6G83 RS12030
gene id: 61652:I6G83_RS12030
uniprot id: A0A140F0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

61652:I6G83 RS19570
gene id: 61652:I6G83_RS19570
uniprot id: A0A448SQ17
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

61652:I6G83 RS01375
gene id: 61652:I6G83_RS01375
uniprot id: A0A126VG64
names: Similarity
messages: Belongs to the ABC transporter superfamily.

61652:I6G83 RS20480
gene id: 61652:I6G83_RS20480
uniprot id: A0A4U9HN08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

61652:I6G83 RS19915
gene id: 61652:I6G83_RS19915
uniprot id: A0A126VJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

61652:I6G83 RS16145
gene id: 61652:I6G83_RS16145
uniprot id: A0A448SV65
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

61652:I6G83 RS19365
gene id: 61652:I6G83_RS19365
uniprot id: A0A4U9HGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

61652:I6G83 RS04860
gene id: 61652:I6G83_RS04860
uniprot id: A0A126VF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS13430
gene id: 61652:I6G83_RS13430
uniprot id: A0A4U9HDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

61652:I6G83 RS03040
gene id: 61652:I6G83_RS03040
uniprot id: A0A4V6JI65
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

61652:I6G83 RS13255
gene id: 61652:I6G83_RS13255
uniprot id: A0A3S4X8X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

61652:I6G83 RS13285
gene id: 61652:I6G83_RS13285
uniprot id: A0A140EZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

61652:I6G83 RS14245
gene id: 61652:I6G83_RS14245
uniprot id: A0A3S4GEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

61652:I6G83 RS05590
gene id: 61652:I6G83_RS05590
uniprot id: A0A447QKX4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

61652:I6G83 RS19275
gene id: 61652:I6G83_RS19275
uniprot id: A0A4U9HGL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

61652:I6G83 RS23040
gene id: 61652:I6G83_RS23040
uniprot id: A0A126VIP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

61652:I6G83 RS07995
gene id: 61652:I6G83_RS07995
uniprot id: A0A4U9HCF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

61652:I6G83 RS01670
gene id: 61652:I6G83_RS01670
uniprot id: A0A447QI63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

61652:I6G83 RS20525
gene id: 61652:I6G83_RS20525
uniprot id: A0A126VIS3
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

61652:I6G83 RS15060
gene id: 61652:I6G83_RS15060
uniprot id: A0A126VLK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS15740
gene id: 61652:I6G83_RS15740
uniprot id: A0A448SVR9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS09125
gene id: 61652:I6G83_RS09125
uniprot id: A0A4U9H943
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

61652:I6G83 RS23445
gene id: 61652:I6G83_RS23445
uniprot id: A0A126VGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

61652:I6G83 RS01380
gene id: 61652:I6G83_RS01380
uniprot id: A0A4U9HPE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61652:I6G83 RS00535
gene id: 61652:I6G83_RS00535
uniprot id: A0A3S4YRY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

61652:I6G83 RS20605
gene id: 61652:I6G83_RS20605
uniprot id: A0A126VIS9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS17465
gene id: 61652:I6G83_RS17465
uniprot id: A0A126VKF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

61652:I6G83 RS02465
gene id: 61652:I6G83_RS02465
uniprot id: A0A126VFJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

61652:I6G83 RS06015
gene id: 61652:I6G83_RS06015
uniprot id: A0A126VDP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS13145
gene id: 61652:I6G83_RS13145
uniprot id: A0A126VMP2
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

61652:I6G83 RS19765
gene id: 61652:I6G83_RS19765
uniprot id: A0A4U9HJJ0
names: Similarity
messages: Belongs to the asparaginase 1 family.

61652:I6G83 RS04280
gene id: 61652:I6G83_RS04280
uniprot id: A0A4U9HSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

61652:I6G83 RS05025
gene id: 61652:I6G83_RS05025
uniprot id: A0A126VE99
names: Similarity
messages: Belongs to the Smg family.

61652:I6G83 RS12600
gene id: 61652:I6G83_RS12600
uniprot id: A0A3S4GDZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

61652:I6G83 RS12120
gene id: 61652:I6G83_RS12120
uniprot id: A0A140F0E5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

61652:I6G83 RS18240
gene id: 61652:I6G83_RS18240
uniprot id: A0A448SS96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS19950
gene id: 61652:I6G83_RS19950
uniprot id: A0A447QVK8
names: Similarity
messages: Belongs to the RutC family.

61652:I6G83 RS19205
gene id: 61652:I6G83_RS19205
uniprot id: A0A3S4GGI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS08040
gene id: 61652:I6G83_RS08040
uniprot id: A0A3S4FSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

61652:I6G83 RS20555
gene id: 61652:I6G83_RS20555
uniprot id: A0A4U9HIA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

61652:I6G83 RS07200
gene id: 61652:I6G83_RS07200
uniprot id: A0A126VD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

61652:I6G83 RS14880
gene id: 61652:I6G83_RS14880
uniprot id: A0A126VNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS06185
gene id: 61652:I6G83_RS06185
uniprot id: A0A447QKY8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

61652:I6G83 RS02510
gene id: 61652:I6G83_RS02510
uniprot id: A0A3S4HZ76
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

61652:I6G83 RS14645
gene id: 61652:I6G83_RS14645
uniprot id: A0A4U9HC68
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

61652:I6G83 RS16595
gene id: 61652:I6G83_RS16595
uniprot id: A0A4U9HDW1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS19675
gene id: 61652:I6G83_RS19675
uniprot id: A0A448SPW2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

61652:I6G83 RS11375
gene id: 61652:I6G83_RS11375
uniprot id: A0A4U9HCM0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

61652:I6G83 RS07945
gene id: 61652:I6G83_RS07945
uniprot id: A0A126VCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

61652:I6G83 RS07435
gene id: 61652:I6G83_RS07435
uniprot id: A0A4U9H7U4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

61652:I6G83 RS02905
gene id: 61652:I6G83_RS02905
uniprot id: A0A3S4WH26
names: Function
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

61652:I6G83 RS19520
gene id: 61652:I6G83_RS19520
uniprot id: A0A3S4FWI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

61652:I6G83 RS17470
gene id: 61652:I6G83_RS17470
uniprot id: A0A448STM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

61652:I6G83 RS07885
gene id: 61652:I6G83_RS07885
uniprot id: A0A4U9H9Y5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

61652:I6G83 RS01210
gene id: 61652:I6G83_RS01210
uniprot id: A0A4U9HR64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

61652:I6G83 RS09740
gene id: 61652:I6G83_RS09740
uniprot id: A0A448S3H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

61652:I6G83 RS23225
gene id: 61652:I6G83_RS23225
uniprot id: A0A4U9HNA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS08200
gene id: 61652:I6G83_RS08200
uniprot id: A0A447QMN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS02900
gene id: 61652:I6G83_RS02900
uniprot id: A0A2X5AE72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

61652:I6G83 RS17065
gene id: 61652:I6G83_RS17065
uniprot id: A0A447QTK5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

61652:I6G83 RS02790
gene id: 61652:I6G83_RS02790
uniprot id: A0A126VFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

61652:I6G83 RS10815
gene id: 61652:I6G83_RS10815
uniprot id: A0A448S2C7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

61652:I6G83 RS20355
gene id: 61652:I6G83_RS20355
uniprot id: A0A4U9HIZ9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS04120
gene id: 61652:I6G83_RS04120
uniprot id: A0A126VER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS05605
gene id: 61652:I6G83_RS05605
uniprot id: A0A126VDU2
names: Similarity
messages: Belongs to the FeoA family.

61652:I6G83 RS01675
gene id: 61652:I6G83_RS01675
uniprot id: A0A3S4X659
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

61652:I6G83 RS06250
gene id: 61652:I6G83_RS06250
uniprot id: A0A3S4WT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

61652:I6G83 RS01255
gene id: 61652:I6G83_RS01255
uniprot id: A0A126VH19
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

61652:I6G83 RS21485
gene id: 61652:I6G83_RS21485
uniprot id: A0A4U9HJZ9
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS02030
gene id: 61652:I6G83_RS02030
uniprot id: A0A4U9HRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

61652:I6G83 RS02235
gene id: 61652:I6G83_RS02235
uniprot id: A0A447QII3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS21395
gene id: 61652:I6G83_RS21395
uniprot id: A0A4U9HJR1
names: Similarity
messages: Belongs to the VgrG protein family.

61652:I6G83 RS01360
gene id: 61652:I6G83_RS01360
uniprot id: A0A448SFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

61652:I6G83 RS14440
gene id: 61652:I6G83_RS14440
uniprot id: A0A4U9HCE1
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS19250
gene id: 61652:I6G83_RS19250
uniprot id: A0A4U9HGK3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

61652:I6G83 RS10950
gene id: 61652:I6G83_RS10950
uniprot id: A0A140F0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

61652:I6G83 RS02375
gene id: 61652:I6G83_RS02375
uniprot id: A0A3S4FPT7
names: Similarity
messages: Belongs to the TPP enzyme family.

61652:I6G83 RS03715
gene id: 61652:I6G83_RS03715
uniprot id: A0A3S4JTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

61652:I6G83 RS19475
gene id: 61652:I6G83_RS19475
uniprot id: A0A3S4JZE3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

61652:I6G83 RS21535
gene id: 61652:I6G83_RS21535
uniprot id: A0A4U9HKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS21470
gene id: 61652:I6G83_RS21470
uniprot id: A0A4U9HKC8
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS19355
gene id: 61652:I6G83_RS19355
uniprot id: A0A4U9HGQ2
names: Similarity
messages: Belongs to the ribulokinase family.

61652:I6G83 RS02110
gene id: 61652:I6G83_RS02110
uniprot id: A0A4U9HV95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

61652:I6G83 RS04505
gene id: 61652:I6G83_RS04505
uniprot id: A0A2X5A5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

61652:I6G83 RS04620
gene id: 61652:I6G83_RS04620
uniprot id: A0A4U9HVF0
names: Similarity
messages: Belongs to the CTP synthase family.

61652:I6G83 RS18110
gene id: 61652:I6G83_RS18110
uniprot id: A0A126VK21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

61652:I6G83 RS01020
gene id: 61652:I6G83_RS01020
uniprot id: A0A3S4HYQ7
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

61652:I6G83 RS19920
gene id: 61652:I6G83_RS19920
uniprot id: A0A3S4GGS8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

61652:I6G83 RS14435
gene id: 61652:I6G83_RS14435
uniprot id: A0A140EZ79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS13050
gene id: 61652:I6G83_RS13050
uniprot id: A0A4U9HB80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

61652:I6G83 RS02245
gene id: 61652:I6G83_RS02245
uniprot id: A0A3S4WWH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

61652:I6G83 RS05270
gene id: 61652:I6G83_RS05270
uniprot id: A0A126VEY0
names: Similarity
messages: Belongs to the SlyX family.

61652:I6G83 RS14625
gene id: 61652:I6G83_RS14625
uniprot id: A0A126VLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

61652:I6G83 RS12445
gene id: 61652:I6G83_RS12445
uniprot id: A0A140F088
names: Similarity
messages: Belongs to the band 7/mec-2 family.

61652:I6G83 RS12410
gene id: 61652:I6G83_RS12410
uniprot id: A0A448S112
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

61652:I6G83 RS22105
gene id: 61652:I6G83_RS22105
uniprot id: A0A4U9HKM0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

61652:I6G83 RS01240
gene id: 61652:I6G83_RS01240
uniprot id: A0A126VI84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61652:I6G83 RS04780
gene id: 61652:I6G83_RS04780
uniprot id: A0A126VEA8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

61652:I6G83 RS12340
gene id: 61652:I6G83_RS12340
uniprot id: A0A448S1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS00280
gene id: 61652:I6G83_RS00280
uniprot id: A0A447QH20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

61652:I6G83 RS02560
gene id: 61652:I6G83_RS02560
uniprot id: A0A447QIK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

61652:I6G83 RS15065
gene id: 61652:I6G83_RS15065
uniprot id: A0A126VLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

61652:I6G83 RS14995
gene id: 61652:I6G83_RS14995
uniprot id: A0A126VMY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

61652:I6G83 RS05970
gene id: 61652:I6G83_RS05970
uniprot id: A0A448S8S4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS21040
gene id: 61652:I6G83_RS21040
uniprot id: A0A3S4G759
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

61652:I6G83 RS07880
gene id: 61652:I6G83_RS07880
uniprot id: A0A126VCQ9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

61652:I6G83 RS01395
gene id: 61652:I6G83_RS01395
uniprot id: A0A3S4Y0M4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS05170
gene id: 61652:I6G83_RS05170
uniprot id: A0A4U9HUI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

61652:I6G83 RS10315
gene id: 61652:I6G83_RS10315
uniprot id: A0A4V6JGK9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

61652:I6G83 RS08560
gene id: 61652:I6G83_RS08560
uniprot id: A0A4U9H8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

61652:I6G83 RS21615
gene id: 61652:I6G83_RS21615
uniprot id: A0A3S4FM15
names: Similarity
messages: Belongs to the ArsC family.

61652:I6G83 RS05200
gene id: 61652:I6G83_RS05200
uniprot id: A0A2X5ENA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

61652:I6G83 RS14640
gene id: 61652:I6G83_RS14640
uniprot id: A0A4U9HE64
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

61652:I6G83 RS12300
gene id: 61652:I6G83_RS12300
uniprot id: A0A140F0B2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

61652:I6G83 RS01225
gene id: 61652:I6G83_RS01225
uniprot id: A0A4U9HPG4
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

61652:I6G83 RS03870
gene id: 61652:I6G83_RS03870
uniprot id: A0A4V6JIA0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

61652:I6G83 RS23050
gene id: 61652:I6G83_RS23050
uniprot id: A0A3S4XIH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS04515
gene id: 61652:I6G83_RS04515
uniprot id: A0A448SB31
names: Similarity
messages: Belongs to the peptidase U62 family.

61652:I6G83 RS14930
gene id: 61652:I6G83_RS14930
uniprot id: A0A4U9HH48
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

61652:I6G83 RS05670
gene id: 61652:I6G83_RS05670
uniprot id: A0A126VDZ8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

61652:I6G83 RS06865
gene id: 61652:I6G83_RS06865
uniprot id: A0A126VDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

61652:I6G83 RS10115
gene id: 61652:I6G83_RS10115
uniprot id: A0A4V6JGI6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

61652:I6G83 RS02710
gene id: 61652:I6G83_RS02710
uniprot id: A0A448SDG9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

61652:I6G83 RS13105
gene id: 61652:I6G83_RS13105
uniprot id: A0A3S4JTY3
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS20000
gene id: 61652:I6G83_RS20000
uniprot id: A0A4U9HHG2
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

61652:I6G83 RS22205
gene id: 61652:I6G83_RS22205
uniprot id: A0A448SKV2
names: Subcellular Location Annotation
messages: Cytoplasm

61652:I6G83 RS18510
gene id: 61652:I6G83_RS18510
uniprot id: A0A4U9HI52
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

61652:I6G83 RS02625
gene id: 61652:I6G83_RS02625
uniprot id: A0A126VFK8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

61652:I6G83 RS05265
gene id: 61652:I6G83_RS05265
uniprot id: A0A126VFF2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

61652:I6G83 RS22745
gene id: 61652:I6G83_RS22745
uniprot id: A0A4U9HLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS10535
gene id: 61652:I6G83_RS10535
uniprot id: A0A140F160
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

61652:I6G83 RS01895
gene id: 61652:I6G83_RS01895
uniprot id: A0A4V6JI16
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

61652:I6G83 RS11415
gene id: 61652:I6G83_RS11415
uniprot id: A0A3S4JTA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

61652:I6G83 RS16420
gene id: 61652:I6G83_RS16420
uniprot id: A0A447QT32
names: Similarity
messages: Belongs to the peptidase S24 family.

61652:I6G83 RS11400
gene id: 61652:I6G83_RS11400
uniprot id: A0A140F0S1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS17565
gene id: 61652:I6G83_RS17565
uniprot id: A0A126VKE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

61652:I6G83 RS05135
gene id: 61652:I6G83_RS05135
uniprot id: A0A126VE64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

61652:I6G83 RS05145
gene id: 61652:I6G83_RS05145
uniprot id: A0A126VG17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

61652:I6G83 RS16220
gene id: 61652:I6G83_RS16220
uniprot id: A0A3S4X364
names: Similarity
messages: Belongs to the UPF0227 family.

61652:I6G83 RS10285
gene id: 61652:I6G83_RS10285
uniprot id: A0A4U9H9U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

61652:I6G83 RS02305
gene id: 61652:I6G83_RS02305
uniprot id: A0A126VFN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

61652:I6G83 RS08625
gene id: 61652:I6G83_RS08625
uniprot id: A0A126VCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS20490
gene id: 61652:I6G83_RS20490
uniprot id: A0A126VKK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

61652:I6G83 RS21915
gene id: 61652:I6G83_RS21915
uniprot id: A0A447QDY1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS02260
gene id: 61652:I6G83_RS02260
uniprot id: A0A4V6JI34
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

61652:I6G83 RS14550
gene id: 61652:I6G83_RS14550
uniprot id: A0A4U9HGV4
names: Subcellular Location Annotation
messages: Membrane

61652:I6G83 RS22875
gene id: 61652:I6G83_RS22875
uniprot id: A0A3S4WZA5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

61652:I6G83 RS12705
gene id: 61652:I6G83_RS12705
uniprot id: A0A447QQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

61652:I6G83 RS21565
gene id: 61652:I6G83_RS21565
uniprot id: A0A4U9HM85
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

61652:I6G83 RS17670
gene id: 61652:I6G83_RS17670
uniprot id: A0A4U9HH01
names: Similarity
messages: Belongs to the GST superfamily.

61652:I6G83 RS11555
gene id: 61652:I6G83_RS11555
uniprot id: A0A448S217
names: Similarity
messages: Belongs to the YkuD family.

61652:I6G83 RS07905
gene id: 61652:I6G83_RS07905
uniprot id: A0A126VEM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS21130
gene id: 61652:I6G83_RS21130
uniprot id: A0A126VI68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

61652:I6G83 RS08770
gene id: 61652:I6G83_RS08770
uniprot id: A0A4U9HCX2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61652:I6G83 RS12450
gene id: 61652:I6G83_RS12450
uniprot id: A0A4U9HD94
names: Similarity
messages: Belongs to the CFA/CMAS family.

61652:I6G83 RS15660
gene id: 61652:I6G83_RS15660
uniprot id: A0A3S4I4B9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

61652:I6G83 RS18795
gene id: 61652:I6G83_RS18795
uniprot id: A0A126VJP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61652:I6G83 RS10480
gene id: 61652:I6G83_RS10480
uniprot id: A0A448S2N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

61652:I6G83 RS13940
gene id: 61652:I6G83_RS13940
uniprot id: A0A3S4GMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61652:I6G83 RS12495
gene id: 61652:I6G83_RS12495
uniprot id: A0A447QQG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

61652:I6G83 RS10300
gene id: 61652:I6G83_RS10300
uniprot id: A0A4U9H9D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
messages: Cell inner membrane
messages: Membrane

61652:I6G83 RS07805
gene id: 61652:I6G83_RS07805
uniprot id: A0A4U9H8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

61652:I6G83 RS02660
gene id: 61652:I6G83_RS02660
uniprot id: A0A4V6JI48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS21245
gene id: 61652:I6G83_RS21245
uniprot id: A0A4U9HNY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

61652:I6G83 RS17200
gene id: 61652:I6G83_RS17200
uniprot id: A0A4U9HJ09
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

61652:I6G83 RS07155
gene id: 61652:I6G83_RS07155
uniprot id: A0A4U9H9J6
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

61652:I6G83 RS21015
gene id: 61652:I6G83_RS21015
uniprot id: A0A448SML1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

61652:I6G83 RS19215
gene id: 61652:I6G83_RS19215
uniprot id: A0A4U9HGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tus family.
messages: Cytoplasm
messages: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

61652:I6G83 RS04815
gene id: 61652:I6G83_RS04815
uniprot id: A0A4U9HU35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61652:I6G83 RS03720
gene id: 61652:I6G83_RS03720
uniprot id: A0A4U9HTP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

61652:I6G83 RS06915
gene id: 61652:I6G83_RS06915
uniprot id: A0A447QLC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

61652:I6G83 RS01005
gene id: 61652:I6G83_RS01005
uniprot id: A0A126VID9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

61652:I6G83 RS17625
gene id: 61652:I6G83_RS17625
uniprot id: A0A447QTZ8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

61652:I6G83 RS10395
gene id: 61652:I6G83_RS10395
uniprot id: A0A4U9H9Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

61652:I6G83 RS05890
gene id: 61652:I6G83_RS05890
uniprot id: A0A4U9HV43
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

61652:I6G83 RS11585
gene id: 61652:I6G83_RS11585
uniprot id: A0A448S1I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

61652:I6G83 RS17900
gene id: 61652:I6G83_RS17900
uniprot id: A0A3S5B1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

61652:I6G83 RS12065
gene id: 61652:I6G83_RS12065
uniprot id: A0A140F0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

61652:I6G83 RS20265
gene id: 61652:I6G83_RS20265
uniprot id: A0A4U9HK39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

61652:I6G83 RS05225
gene id: 61652:I6G83_RS05225
uniprot id: A0A126VE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

61652:I6G83 RS11520
gene id: 61652:I6G83_RS11520
uniprot id: A0A3S5ALU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

61652:I6G83 RS16155
gene id: 61652:I6G83_RS16155
uniprot id: A0A4U9HDA6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

61652:I6G83 RS12665
gene id: 61652:I6G83_RS12665
uniprot id: A0A4U9HB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

61652:I6G83 RS19440
gene id: 61652:I6G83_RS19440
uniprot id: A0A126VKQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS22255
gene id: 61652:I6G83_RS22255
uniprot id: A0A4U9HN60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61652:I6G83 RS21810
gene id: 61652:I6G83_RS21810
uniprot id: A0A126VHT6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

61652:I6G83 RS02180
gene id: 61652:I6G83_RS02180
uniprot id: A0A4U9HVC1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

61652:I6G83 RS16030
gene id: 61652:I6G83_RS16030
uniprot id: A0A126VN29
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

61652:I6G83 RS11580
gene id: 61652:I6G83_RS11580
uniprot id: A0A140F0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

61652:I6G83 RS05560
gene id: 61652:I6G83_RS05560
uniprot id: A0A126VDV5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

61652:I6G83 RS08590
gene id: 61652:I6G83_RS08590
uniprot id: A0A4U9HAB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

61652:I6G83 RS17910
gene id: 61652:I6G83_RS17910
uniprot id: A0A447QU60
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

61652:I6G83 RS13230
gene id: 61652:I6G83_RS13230
uniprot id: A0A4U9HBQ9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

61652:I6G83 RS18490
gene id: 61652:I6G83_RS18490
uniprot id: A0A126VJU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

61652:I6G83 RS05075
gene id: 61652:I6G83_RS05075
uniprot id: A0A2X5CKX0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

61652:I6G83 RS06190
gene id: 61652:I6G83_RS06190
uniprot id: A0A3S4I0K1
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

61652:I6G83 RS05355
gene id: 61652:I6G83_RS05355
uniprot id: A0A4U9HUF2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

61652:I6G83 RS17970
gene id: 61652:I6G83_RS17970
uniprot id: A0A4U9HFC8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

61652:I6G83 RS02520
gene id: 61652:I6G83_RS02520
uniprot id: A0A4V6YXX5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.