610130:CLOSA RS19590
gene id: 610130:CLOSA_RS19590
uniprot id: D9R0I2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

610130:CLOSA RS08060
gene id: 610130:CLOSA_RS08060
uniprot id: D9RAA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

610130:CLOSA RS20685
gene id: 610130:CLOSA_RS20685
uniprot id: D9R2K0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS15255
gene id: 610130:CLOSA_RS15255
uniprot id: D9R7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02130
gene id: 610130:CLOSA_RS02130
uniprot id: D9R3T1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

610130:CLOSA RS08870
gene id: 610130:CLOSA_RS08870
uniprot id: D9QZ92
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

610130:CLOSA RS11760
gene id: 610130:CLOSA_RS11760
uniprot id: D9R3F3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS12420
gene id: 610130:CLOSA_RS12420
uniprot id: D9R4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

610130:CLOSA RS07695
gene id: 610130:CLOSA_RS07695
uniprot id: D9R9R7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

610130:CLOSA RS07590
gene id: 610130:CLOSA_RS07590
uniprot id: D9R9P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

610130:CLOSA RS08160
gene id: 610130:CLOSA_RS08160
uniprot id: D9RAC9
names: Similarity
messages: Belongs to the GARS family.

610130:CLOSA RS04785
gene id: 610130:CLOSA_RS04785
uniprot id: D9R6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS08315
gene id: 610130:CLOSA_RS08315
uniprot id: D9RAF8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11860
gene id: 610130:CLOSA_RS11860
uniprot id: D9R3H3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

610130:CLOSA RS20375
gene id: 610130:CLOSA_RS20375
uniprot id: D9R1P4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS08150
gene id: 610130:CLOSA_RS08150
uniprot id: D9RAC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

610130:CLOSA RS17360
gene id: 610130:CLOSA_RS17360
uniprot id: D9RA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

610130:CLOSA RS10575
gene id: 610130:CLOSA_RS10575
uniprot id: D9R224
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

610130:CLOSA RS16490
gene id: 610130:CLOSA_RS16490
uniprot id: D9R967
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS20655
gene id: 610130:CLOSA_RS20655
uniprot id: D9R2J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

610130:CLOSA RS19890
gene id: 610130:CLOSA_RS19890
uniprot id: D9R1F2
names: Similarity
messages: Belongs to the TPP enzyme family.

610130:CLOSA RS14845
gene id: 610130:CLOSA_RS14845
uniprot id: D9R765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS12385
gene id: 610130:CLOSA_RS12385
uniprot id: D9R4F3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

610130:CLOSA RS10435
gene id: 610130:CLOSA_RS10435
uniprot id: D9R198
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS05570
gene id: 610130:CLOSA_RS05570
uniprot id: D9R7H1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

610130:CLOSA RS06300
gene id: 610130:CLOSA_RS06300
uniprot id: D9R890
names: Similarity
messages: Belongs to the LacAB/RpiB family.

610130:CLOSA RS03145
gene id: 610130:CLOSA_RS03145
uniprot id: D9R4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

610130:CLOSA RS14885
gene id: 610130:CLOSA_RS14885
uniprot id: D9R773
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS18900
gene id: 610130:CLOSA_RS18900
uniprot id: D9QZQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

610130:CLOSA RS03630
gene id: 610130:CLOSA_RS03630
uniprot id: D9R5B5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

610130:CLOSA RS04880
gene id: 610130:CLOSA_RS04880
uniprot id: D9R6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05215
gene id: 610130:CLOSA_RS05215
uniprot id: D9R6X3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02115
gene id: 610130:CLOSA_RS02115
uniprot id: D9R3S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS21080
gene id: 610130:CLOSA_RS21080
uniprot id: D9R3I2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

610130:CLOSA RS08365
gene id: 610130:CLOSA_RS08365
uniprot id: D9RAG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

610130:CLOSA RS18500
gene id: 610130:CLOSA_RS18500
uniprot id: D9QZH0
names: Similarity
messages: Belongs to the PemK/MazF family.

610130:CLOSA RS09680
gene id: 610130:CLOSA_RS09680
uniprot id: D9R041
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS16750
gene id: 610130:CLOSA_RS16750
uniprot id: D9R9B8
names: Similarity
messages: Belongs to the peptidase M56 family.

610130:CLOSA RS12165
gene id: 610130:CLOSA_RS12165
uniprot id: D9R4B3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

610130:CLOSA RS07325
gene id: 610130:CLOSA_RS07325
uniprot id: D9R9J2
names: Subcellular Location Annotation
messages: Cell membrane

610130:CLOSA RS16855
gene id: 610130:CLOSA_RS16855
uniprot id: D9R9D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

610130:CLOSA RS05210
gene id: 610130:CLOSA_RS05210
uniprot id: D9R6X2
names: Similarity
messages: Belongs to the GerABKA family.

610130:CLOSA RS02650
gene id: 610130:CLOSA_RS02650
uniprot id: D9R435
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

610130:CLOSA RS18855
gene id: 610130:CLOSA_RS18855
uniprot id: D9QZP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

610130:CLOSA RS17375
gene id: 610130:CLOSA_RS17375
uniprot id: D9RA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

610130:CLOSA RS16880
gene id: 610130:CLOSA_RS16880
uniprot id: D9R9E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS09400
gene id: 610130:CLOSA_RS09400
uniprot id: D9QZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

610130:CLOSA RS13145
gene id: 610130:CLOSA_RS13145
uniprot id: D9R568
names: Similarity
messages: Belongs to the HypE family.

610130:CLOSA RS17080
gene id: 610130:CLOSA_RS17080
uniprot id: D9R9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS01330
gene id: 610130:CLOSA_RS01330
uniprot id: D9R1Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

610130:CLOSA RS15785
gene id: 610130:CLOSA_RS15785
uniprot id: D9R827
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS21630
gene id: 610130:CLOSA_RS21630
uniprot id: D9R4M3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

610130:CLOSA RS04125
gene id: 610130:CLOSA_RS04125
uniprot id: D9R5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

610130:CLOSA RS08045
gene id: 610130:CLOSA_RS08045
uniprot id: D9RAA6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

610130:CLOSA RS07730
gene id: 610130:CLOSA_RS07730
uniprot id: D9R9S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

610130:CLOSA RS10490
gene id: 610130:CLOSA_RS10490
uniprot id: D9R1B0
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

610130:CLOSA RS19025
gene id: 610130:CLOSA_RS19025
uniprot id: D9QZS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

610130:CLOSA RS09915
gene id: 610130:CLOSA_RS09915
uniprot id: D9R0Z2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

610130:CLOSA RS09925
gene id: 610130:CLOSA_RS09925
uniprot id: D9R0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

610130:CLOSA RS02485
gene id: 610130:CLOSA_RS02485
uniprot id: D9R403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS04465
gene id: 610130:CLOSA_RS04465
uniprot id: D9R647
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS21050
gene id: 610130:CLOSA_RS21050
uniprot id: D9R3H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

610130:CLOSA RS13065
gene id: 610130:CLOSA_RS13065
uniprot id: D9R551
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

610130:CLOSA RS01340
gene id: 610130:CLOSA_RS01340
uniprot id: D9R200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Membrane

610130:CLOSA RS13025
gene id: 610130:CLOSA_RS13025
uniprot id: D9R544
names: Similarity
messages: Belongs to the hemerythrin family.

610130:CLOSA RS00500
gene id: 610130:CLOSA_RS00500
uniprot id: D9R0T4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20150
gene id: 610130:CLOSA_RS20150
uniprot id: D9R1K3
names: Similarity
messages: Belongs to the EutP/PduV family.

610130:CLOSA RS14990
gene id: 610130:CLOSA_RS14990
uniprot id: D9R794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09320
gene id: 610130:CLOSA_RS09320
uniprot id: D9QZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

610130:CLOSA RS08340
gene id: 610130:CLOSA_RS08340
uniprot id: D9RAG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

610130:CLOSA RS18215
gene id: 610130:CLOSA_RS18215
uniprot id: D9RAU5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

610130:CLOSA RS12700
gene id: 610130:CLOSA_RS12700
uniprot id: D9R4Y1
names: Similarity
messages: Belongs to the carbamate kinase family.

610130:CLOSA RS04065
gene id: 610130:CLOSA_RS04065
uniprot id: D9R5X7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS04590
gene id: 610130:CLOSA_RS04590
uniprot id: D9R673
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

610130:CLOSA RS07885
gene id: 610130:CLOSA_RS07885
uniprot id: D9R9V2
names: Similarity
messages: Belongs to the RutC family.

610130:CLOSA RS01310
gene id: 610130:CLOSA_RS01310
uniprot id: D9R1Z4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06525
gene id: 610130:CLOSA_RS06525
uniprot id: D9R8D2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

610130:CLOSA RS00915
gene id: 610130:CLOSA_RS00915
uniprot id: D9R1S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

610130:CLOSA RS18695
gene id: 610130:CLOSA_RS18695
uniprot id: D9QZK8
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS14160
gene id: 610130:CLOSA_RS14160
uniprot id: D9R6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11845
gene id: 610130:CLOSA_RS11845
uniprot id: D9R3H0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS05425
gene id: 610130:CLOSA_RS05425
uniprot id: D9R7E3
names: Subcellular Location Annotation
messages: Cell membrane

610130:CLOSA RS18930
gene id: 610130:CLOSA_RS18930
uniprot id: D9QZQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

610130:CLOSA RS14680
gene id: 610130:CLOSA_RS14680
uniprot id: D9R732
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

610130:CLOSA RS06560
gene id: 610130:CLOSA_RS06560
uniprot id: D9R8D9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS09060
gene id: 610130:CLOSA_RS09060
uniprot id: D9QZC4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

610130:CLOSA RS05355
gene id: 610130:CLOSA_RS05355
uniprot id: D9R7C8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

610130:CLOSA RS00250
gene id: 610130:CLOSA_RS00250
uniprot id: D9R0N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Belongs to the AccA family.
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

610130:CLOSA RS12755
gene id: 610130:CLOSA_RS12755
uniprot id: D9R4Z2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

610130:CLOSA RS11185
gene id: 610130:CLOSA_RS11185
uniprot id: D9R2E3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

610130:CLOSA RS02675
gene id: 610130:CLOSA_RS02675
uniprot id: D9R440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09875
gene id: 610130:CLOSA_RS09875
uniprot id: D9R079
names: Similarity
messages: Belongs to the CinA family.

610130:CLOSA RS09205
gene id: 610130:CLOSA_RS09205
uniprot id: D9QZF3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS19955
gene id: 610130:CLOSA_RS19955
uniprot id: D9R1G5
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10855
gene id: 610130:CLOSA_RS10855
uniprot id: D9R280
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS08425
gene id: 610130:CLOSA_RS08425
uniprot id: D9RAI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

610130:CLOSA RS03510
gene id: 610130:CLOSA_RS03510
uniprot id: D9R592
names: Similarity
messages: Belongs to the pyruvate kinase family.

610130:CLOSA RS02980
gene id: 610130:CLOSA_RS02980
uniprot id: D9R4M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

610130:CLOSA RS09655
gene id: 610130:CLOSA_RS09655
uniprot id: D9R036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS03575
gene id: 610130:CLOSA_RS03575
uniprot id: D9R5A4
names: Subcellular Location Annotation
messages: Cell membrane

610130:CLOSA RS01350
gene id: 610130:CLOSA_RS01350
uniprot id: D9R202
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS06695
gene id: 610130:CLOSA_RS06695
uniprot id: D9R8U0
names: Similarity
messages: Belongs to the UPF0473 family.

610130:CLOSA RS13605
gene id: 610130:CLOSA_RS13605
uniprot id: D9R5S9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS10380
gene id: 610130:CLOSA_RS10380
uniprot id: D9R188
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS11570
gene id: 610130:CLOSA_RS11570
uniprot id: D9R3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

610130:CLOSA RS14520
gene id: 610130:CLOSA_RS14520
uniprot id: D9R702
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

610130:CLOSA RS18985
gene id: 610130:CLOSA_RS18985
uniprot id: D9QZR7
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS17680
gene id: 610130:CLOSA_RS17680
uniprot id: D9RA67
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS15510
gene id: 610130:CLOSA_RS15510
uniprot id: D9R7X3
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS01325
gene id: 610130:CLOSA_RS01325
uniprot id: D9R1Z7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS21295
gene id: 610130:CLOSA_RS21295
uniprot id: D9R3M4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS16195
gene id: 610130:CLOSA_RS16195
uniprot id: D9R8N1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS05635
gene id: 610130:CLOSA_RS05635
uniprot id: D9R7I4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

610130:CLOSA RS20025
gene id: 610130:CLOSA_RS20025
uniprot id: D9R1H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS14915
gene id: 610130:CLOSA_RS14915
uniprot id: D9R779
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS10710
gene id: 610130:CLOSA_RS10710
uniprot id: D9R251
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

610130:CLOSA RS21485
gene id: 610130:CLOSA_RS21485
uniprot id: D9R3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

610130:CLOSA RS07860
gene id: 610130:CLOSA_RS07860
uniprot id: D9R9U7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

610130:CLOSA RS18150
gene id: 610130:CLOSA_RS18150
uniprot id: D9RAT4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

610130:CLOSA RS01110
gene id: 610130:CLOSA_RS01110
uniprot id: D9R1V4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS01195
gene id: 610130:CLOSA_RS01195
uniprot id: D9R1X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

610130:CLOSA RS08410
gene id: 610130:CLOSA_RS08410
uniprot id: D9RAH7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07255
gene id: 610130:CLOSA_RS07255
uniprot id: D9R954
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS01675
gene id: 610130:CLOSA_RS01675
uniprot id: D9R2W7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS04875
gene id: 610130:CLOSA_RS04875
uniprot id: D9R6Q8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

610130:CLOSA RS10900
gene id: 610130:CLOSA_RS10900
uniprot id: D9R289
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

610130:CLOSA RS12455
gene id: 610130:CLOSA_RS12455
uniprot id: D9R4G7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07130
gene id: 610130:CLOSA_RS07130
uniprot id: D9R926
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

610130:CLOSA RS11625
gene id: 610130:CLOSA_RS11625
uniprot id: D9R3C7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

610130:CLOSA RS19775
gene id: 610130:CLOSA_RS19775
uniprot id: D9R1D1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

610130:CLOSA RS19575
gene id: 610130:CLOSA_RS19575
uniprot id: D9R0H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS03360
gene id: 610130:CLOSA_RS03360
uniprot id: D9R4T4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10620
gene id: 610130:CLOSA_RS10620
uniprot id: D9R233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02350
gene id: 610130:CLOSA_RS02350
uniprot id: D9R3X6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

610130:CLOSA RS12305
gene id: 610130:CLOSA_RS12305
uniprot id: D9R4D8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

610130:CLOSA RS18670
gene id: 610130:CLOSA_RS18670
uniprot id: D9QZK3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

610130:CLOSA RS10725
gene id: 610130:CLOSA_RS10725
uniprot id: D9R254
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

610130:CLOSA RS18745
gene id: 610130:CLOSA_RS18745
uniprot id: D9QZL8
names: Similarity
messages: Belongs to the ParB family.

610130:CLOSA RS05840
gene id: 610130:CLOSA_RS05840
uniprot id: D9R7M5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

610130:CLOSA RS09145
gene id: 610130:CLOSA_RS09145
uniprot id: D9QZE1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS11850
gene id: 610130:CLOSA_RS11850
uniprot id: D9R3H1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

610130:CLOSA RS01255
gene id: 610130:CLOSA_RS01255
uniprot id: D9R1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS20070
gene id: 610130:CLOSA_RS20070
uniprot id: D9R1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

610130:CLOSA RS09375
gene id: 610130:CLOSA_RS09375
uniprot id: D9QZY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

610130:CLOSA RS19825
gene id: 610130:CLOSA_RS19825
uniprot id: D9R1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11360
gene id: 610130:CLOSA_RS11360
uniprot id: D9R381
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS00365
gene id: 610130:CLOSA_RS00365
uniprot id: D9R0Q7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

610130:CLOSA RS03505
gene id: 610130:CLOSA_RS03505
uniprot id: D9R591
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18295
gene id: 610130:CLOSA_RS18295
uniprot id: D9RAW0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

610130:CLOSA RS05895
gene id: 610130:CLOSA_RS05895
uniprot id: D9R7N3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS06920
gene id: 610130:CLOSA_RS06920
uniprot id: D9R8Y3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

610130:CLOSA RS10255
gene id: 610130:CLOSA_RS10255
uniprot id: D9R161
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

610130:CLOSA RS02015
gene id: 610130:CLOSA_RS02015
uniprot id: D9R331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

610130:CLOSA RS06705
gene id: 610130:CLOSA_RS06705
uniprot id: D9R8U2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

610130:CLOSA RS10000
gene id: 610130:CLOSA_RS10000
uniprot id: D9R109
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

610130:CLOSA RS06815
gene id: 610130:CLOSA_RS06815
uniprot id: D9R8W4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

610130:CLOSA RS15935
gene id: 610130:CLOSA_RS15935
uniprot id: D9R8I3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

610130:CLOSA RS08100
gene id: 610130:CLOSA_RS08100
uniprot id: D9RAB7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

610130:CLOSA RS16730
gene id: 610130:CLOSA_RS16730
uniprot id: D9R9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS04995
gene id: 610130:CLOSA_RS04995
uniprot id: D9R6T1
names: Similarity
messages: Belongs to the UPF0045 family.

610130:CLOSA RS01170
gene id: 610130:CLOSA_RS01170
uniprot id: D9R1W6
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

610130:CLOSA RS16450
gene id: 610130:CLOSA_RS16450
uniprot id: D9R8T1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

610130:CLOSA RS09175
gene id: 610130:CLOSA_RS09175
uniprot id: D9QZE7
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

610130:CLOSA RS04095
gene id: 610130:CLOSA_RS04095
uniprot id: D9R5Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

610130:CLOSA RS10410
gene id: 610130:CLOSA_RS10410
uniprot id: D9R193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

610130:CLOSA RS15140
gene id: 610130:CLOSA_RS15140
uniprot id: D9R7C3
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19225
gene id: 610130:CLOSA_RS19225
uniprot id: D9R0A9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS01595
gene id: 610130:CLOSA_RS01595
uniprot id: D9R2V1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

610130:CLOSA RS15470
gene id: 610130:CLOSA_RS15470
uniprot id: D9R7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

610130:CLOSA RS05250
gene id: 610130:CLOSA_RS05250
uniprot id: D9R6Y0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS22330
gene id: 610130:CLOSA_RS22330
uniprot id: D9QZN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

610130:CLOSA RS16915
gene id: 610130:CLOSA_RS16915
uniprot id: D9R9E7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

610130:CLOSA RS17655
gene id: 610130:CLOSA_RS17655
uniprot id: D9RA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

610130:CLOSA RS19965
gene id: 610130:CLOSA_RS19965
uniprot id: D9R1G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

610130:CLOSA RS05535
gene id: 610130:CLOSA_RS05535
uniprot id: D9R7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

610130:CLOSA RS10735
gene id: 610130:CLOSA_RS10735
uniprot id: D9R256
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

610130:CLOSA RS18260
gene id: 610130:CLOSA_RS18260
uniprot id: D9RAV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

610130:CLOSA RS20715
gene id: 610130:CLOSA_RS20715
uniprot id: D9R2K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

610130:CLOSA RS06720
gene id: 610130:CLOSA_RS06720
uniprot id: D9R8U5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

610130:CLOSA RS19860
gene id: 610130:CLOSA_RS19860
uniprot id: D9R1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02100
gene id: 610130:CLOSA_RS02100
uniprot id: D9R348
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

610130:CLOSA RS10630
gene id: 610130:CLOSA_RS10630
uniprot id: D9R235
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

610130:CLOSA RS04235
gene id: 610130:CLOSA_RS04235
uniprot id: D9R605
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

610130:CLOSA RS00045
gene id: 610130:CLOSA_RS00045
uniprot id: D9QZV3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

610130:CLOSA RS06655
gene id: 610130:CLOSA_RS06655
uniprot id: D9R8T3
names: Similarity
messages: Belongs to the GSP E family.

610130:CLOSA RS04560
gene id: 610130:CLOSA_RS04560
uniprot id: D9R667
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

610130:CLOSA RS06675
gene id: 610130:CLOSA_RS06675
uniprot id: D9R8T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

610130:CLOSA RS18405
gene id: 610130:CLOSA_RS18405
uniprot id: D9RAY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS12870
gene id: 610130:CLOSA_RS12870
uniprot id: D9R514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS00890
gene id: 610130:CLOSA_RS00890
uniprot id: D9R1R9
names: Similarity
messages: Belongs to the hemerythrin family.

610130:CLOSA RS17460
gene id: 610130:CLOSA_RS17460
uniprot id: D9RA24
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

610130:CLOSA RS04555
gene id: 610130:CLOSA_RS04555
uniprot id: D9R666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

610130:CLOSA RS20895
gene id: 610130:CLOSA_RS20895
uniprot id: D9R2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

610130:CLOSA RS09080
gene id: 610130:CLOSA_RS09080
uniprot id: D9QZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

610130:CLOSA RS10295
gene id: 610130:CLOSA_RS10295
uniprot id: D9R169
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS15230
gene id: 610130:CLOSA_RS15230
uniprot id: D9R7R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

610130:CLOSA RS01970
gene id: 610130:CLOSA_RS01970
uniprot id: D9R322
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS04495
gene id: 610130:CLOSA_RS04495
uniprot id: D9R654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15415
gene id: 610130:CLOSA_RS15415
uniprot id: D9R7V4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

610130:CLOSA RS14835
gene id: 610130:CLOSA_RS14835
uniprot id: D9R763
names: Similarity
messages: Belongs to the DSD1 family.

610130:CLOSA RS12570
gene id: 610130:CLOSA_RS12570
uniprot id: D9R4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

610130:CLOSA RS19755
gene id: 610130:CLOSA_RS19755
uniprot id: D9R1C7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

610130:CLOSA RS11830
gene id: 610130:CLOSA_RS11830
uniprot id: D9R3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

610130:CLOSA RS07780
gene id: 610130:CLOSA_RS07780
uniprot id: D9R9T3
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS13695
gene id: 610130:CLOSA_RS13695
uniprot id: D9R5U5
names: Similarity
messages: Belongs to the Fur family.

610130:CLOSA RS00505
gene id: 610130:CLOSA_RS00505
uniprot id: D9R0T5
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

610130:CLOSA RS21245
gene id: 610130:CLOSA_RS21245
uniprot id: D9R3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS07995
gene id: 610130:CLOSA_RS07995
uniprot id: D9RA96
names: Similarity
messages: Belongs to the SAICAR synthetase family.

610130:CLOSA RS20180
gene id: 610130:CLOSA_RS20180
uniprot id: D9R1K9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS16680
gene id: 610130:CLOSA_RS16680
uniprot id: D9R9A4
names: Similarity
messages: Belongs to the IlvD/Edd family.

610130:CLOSA RS02070
gene id: 610130:CLOSA_RS02070
uniprot id: D9R342
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

610130:CLOSA RS09425
gene id: 610130:CLOSA_RS09425
uniprot id: D9QZZ6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

610130:CLOSA RS14610
gene id: 610130:CLOSA_RS14610
uniprot id: D9R718
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

610130:CLOSA RS03080
gene id: 610130:CLOSA_RS03080
uniprot id: D9R4P4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

610130:CLOSA RS17335
gene id: 610130:CLOSA_RS17335
uniprot id: D9RA00
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

610130:CLOSA RS21555
gene id: 610130:CLOSA_RS21555
uniprot id: D9R3S5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

610130:CLOSA RS16900
gene id: 610130:CLOSA_RS16900
uniprot id: D9R9E4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS11105
gene id: 610130:CLOSA_RS11105
uniprot id: D9R2C7
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

610130:CLOSA RS14925
gene id: 610130:CLOSA_RS14925
uniprot id: D9R781
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

610130:CLOSA RS01765
gene id: 610130:CLOSA_RS01765
uniprot id: D9R2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11495
gene id: 610130:CLOSA_RS11495
uniprot id: D9R3A6
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19550
gene id: 610130:CLOSA_RS19550
uniprot id: D9R0H4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

610130:CLOSA RS17435
gene id: 610130:CLOSA_RS17435
uniprot id: D9RA19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS18820
gene id: 610130:CLOSA_RS18820
uniprot id: D9QZN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

610130:CLOSA RS06180
gene id: 610130:CLOSA_RS06180
uniprot id: D9R866
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS00145
gene id: 610130:CLOSA_RS00145
uniprot id: D9QZW2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

610130:CLOSA RS16175
gene id: 610130:CLOSA_RS16175
uniprot id: D9R8M7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS14895
gene id: 610130:CLOSA_RS14895
uniprot id: D9R775
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS09825
gene id: 610130:CLOSA_RS09825
uniprot id: D9R069
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10585
gene id: 610130:CLOSA_RS10585
uniprot id: D9R226
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

610130:CLOSA RS11755
gene id: 610130:CLOSA_RS11755
uniprot id: D9R3F2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

610130:CLOSA RS08505
gene id: 610130:CLOSA_RS08505
uniprot id: D9RAJ6
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS16885
gene id: 610130:CLOSA_RS16885
uniprot id: D9R9E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

610130:CLOSA RS09830
gene id: 610130:CLOSA_RS09830
uniprot id: D9R070
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS12025
gene id: 610130:CLOSA_RS12025
uniprot id: D9R484
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

610130:CLOSA RS12155
gene id: 610130:CLOSA_RS12155
uniprot id: D9R4B1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

610130:CLOSA RS10300
gene id: 610130:CLOSA_RS10300
uniprot id: D9R170
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10365
gene id: 610130:CLOSA_RS10365
uniprot id: D9R184
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS11775
gene id: 610130:CLOSA_RS11775
uniprot id: D9R3F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

610130:CLOSA RS15300
gene id: 610130:CLOSA_RS15300
uniprot id: D9R7T3
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

610130:CLOSA RS05185
gene id: 610130:CLOSA_RS05185
uniprot id: D9R6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

610130:CLOSA RS04585
gene id: 610130:CLOSA_RS04585
uniprot id: D9R672
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

610130:CLOSA RS04675
gene id: 610130:CLOSA_RS04675
uniprot id: D9R690
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

610130:CLOSA RS00005
gene id: 610130:CLOSA_RS00005
uniprot id: D9QZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

610130:CLOSA RS14670
gene id: 610130:CLOSA_RS14670
uniprot id: D9R730
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS21750
gene id: 610130:CLOSA_RS21750
uniprot id: D9R3F4
names: Subcellular Location Annotation
messages: Cell membrane

610130:CLOSA RS20610
gene id: 610130:CLOSA_RS20610
uniprot id: D9R2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

610130:CLOSA RS06760
gene id: 610130:CLOSA_RS06760
uniprot id: D9R8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

610130:CLOSA RS19690
gene id: 610130:CLOSA_RS19690
uniprot id: D9R0K2
names: Similarity
messages: Belongs to the DEAD box helicase family.

610130:CLOSA RS08040
gene id: 610130:CLOSA_RS08040
uniprot id: D9RAA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

610130:CLOSA RS06135
gene id: 610130:CLOSA_RS06135
uniprot id: D9R857
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18880
gene id: 610130:CLOSA_RS18880
uniprot id: D9QZP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

610130:CLOSA RS09855
gene id: 610130:CLOSA_RS09855
uniprot id: D9R075
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

610130:CLOSA RS20235
gene id: 610130:CLOSA_RS20235
uniprot id: D9R1M0
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS14985
gene id: 610130:CLOSA_RS14985
uniprot id: D9R793
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

610130:CLOSA RS02615
gene id: 610130:CLOSA_RS02615
uniprot id: D9R429
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

610130:CLOSA RS02120
gene id: 610130:CLOSA_RS02120
uniprot id: D9R3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05365
gene id: 610130:CLOSA_RS05365
uniprot id: D9R7D0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

610130:CLOSA RS10610
gene id: 610130:CLOSA_RS10610
uniprot id: D9R231
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

610130:CLOSA RS08805
gene id: 610130:CLOSA_RS08805
uniprot id: D9QZ81
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS16785
gene id: 610130:CLOSA_RS16785
uniprot id: D9R9C3
names: Similarity
messages: Belongs to the transpeptidase family.

610130:CLOSA RS14055
gene id: 610130:CLOSA_RS14055
uniprot id: D9R6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

610130:CLOSA RS18905
gene id: 610130:CLOSA_RS18905
uniprot id: D9QZQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

610130:CLOSA RS14775
gene id: 610130:CLOSA_RS14775
uniprot id: D9R751
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS17035
gene id: 610130:CLOSA_RS17035
uniprot id: D9R9H2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

610130:CLOSA RS17535
gene id: 610130:CLOSA_RS17535
uniprot id: D9RA39
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS04275
gene id: 610130:CLOSA_RS04275
uniprot id: D9R613
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

610130:CLOSA RS13445
gene id: 610130:CLOSA_RS13445
uniprot id: D9R5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

610130:CLOSA RS13715
gene id: 610130:CLOSA_RS13715
uniprot id: D9R5U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

610130:CLOSA RS21610
gene id: 610130:CLOSA_RS21610
uniprot id: D9R449
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

610130:CLOSA RS10635
gene id: 610130:CLOSA_RS10635
uniprot id: D9R236
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

610130:CLOSA RS17820
gene id: 610130:CLOSA_RS17820
uniprot id: D9RAM0
names: Similarity
messages: Belongs to the peptidase A24 family.

610130:CLOSA RS18390
gene id: 610130:CLOSA_RS18390
uniprot id: D9RAX8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

610130:CLOSA RS11190
gene id: 610130:CLOSA_RS11190
uniprot id: D9R2E4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

610130:CLOSA RS05300
gene id: 610130:CLOSA_RS05300
uniprot id: D9R6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

610130:CLOSA RS10375
gene id: 610130:CLOSA_RS10375
uniprot id: D9R187
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

610130:CLOSA RS16205
gene id: 610130:CLOSA_RS16205
uniprot id: D9R8N2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

610130:CLOSA RS14920
gene id: 610130:CLOSA_RS14920
uniprot id: D9R780
names: Similarity
messages: Belongs to the ribF family.

610130:CLOSA RS11945
gene id: 610130:CLOSA_RS11945
uniprot id: D9R469
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

610130:CLOSA RS05070
gene id: 610130:CLOSA_RS05070
uniprot id: D9R6U4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18055
gene id: 610130:CLOSA_RS18055
uniprot id: D9RAR5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

610130:CLOSA RS16485
gene id: 610130:CLOSA_RS16485
uniprot id: D9R966
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

610130:CLOSA RS18490
gene id: 610130:CLOSA_RS18490
uniprot id: D9QZG8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS12580
gene id: 610130:CLOSA_RS12580
uniprot id: D9R4V7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

610130:CLOSA RS00370
gene id: 610130:CLOSA_RS00370
uniprot id: D9R0Q8
names: Similarity
messages: Belongs to the EamA transporter family.

610130:CLOSA RS06105
gene id: 610130:CLOSA_RS06105
uniprot id: D9R851
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS21885
gene id: 610130:CLOSA_RS21885
uniprot id: D9R9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

610130:CLOSA RS03150
gene id: 610130:CLOSA_RS03150
uniprot id: D9R4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

610130:CLOSA RS02570
gene id: 610130:CLOSA_RS02570
uniprot id: D9R420
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

610130:CLOSA RS11230
gene id: 610130:CLOSA_RS11230
uniprot id: D9R355
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20935
gene id: 610130:CLOSA_RS20935
uniprot id: D9R2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05595
gene id: 610130:CLOSA_RS05595
uniprot id: D9R7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

610130:CLOSA RS10265
gene id: 610130:CLOSA_RS10265
uniprot id: D9R163
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS18365
gene id: 610130:CLOSA_RS18365
uniprot id: D9RAX4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

610130:CLOSA RS17400
gene id: 610130:CLOSA_RS17400
uniprot id: D9RA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

610130:CLOSA RS04795
gene id: 610130:CLOSA_RS04795
uniprot id: D9R6P1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

610130:CLOSA RS08010
gene id: 610130:CLOSA_RS08010
uniprot id: D9RA99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS13475
gene id: 610130:CLOSA_RS13475
uniprot id: D9R5Q4
names: Similarity
messages: Belongs to the CdaR family.

610130:CLOSA RS04720
gene id: 610130:CLOSA_RS04720
uniprot id: D9R6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

610130:CLOSA RS20630
gene id: 610130:CLOSA_RS20630
uniprot id: D9R2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS18960
gene id: 610130:CLOSA_RS18960
uniprot id: D9QZR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

610130:CLOSA RS01640
gene id: 610130:CLOSA_RS01640
uniprot id: D9R2W1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

610130:CLOSA RS05615
gene id: 610130:CLOSA_RS05615
uniprot id: D9R7I0
names: Similarity
messages: Belongs to the UxaA family.

610130:CLOSA RS20560
gene id: 610130:CLOSA_RS20560
uniprot id: D9R2H8
names: Similarity
messages: Belongs to the Fur family.

610130:CLOSA RS01865
gene id: 610130:CLOSA_RS01865
uniprot id: D9R304
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS11225
gene id: 610130:CLOSA_RS11225
uniprot id: D9R354
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS14735
gene id: 610130:CLOSA_RS14735
uniprot id: D9R743
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

610130:CLOSA RS09635
gene id: 610130:CLOSA_RS09635
uniprot id: D9R033
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

610130:CLOSA RS03110
gene id: 610130:CLOSA_RS03110
uniprot id: D9R4Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09395
gene id: 610130:CLOSA_RS09395
uniprot id: D9QZZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

610130:CLOSA RS04820
gene id: 610130:CLOSA_RS04820
uniprot id: D9R6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

610130:CLOSA RS05815
gene id: 610130:CLOSA_RS05815
uniprot id: D9R7M0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

610130:CLOSA RS12735
gene id: 610130:CLOSA_RS12735
uniprot id: D9R4Y8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS11935
gene id: 610130:CLOSA_RS11935
uniprot id: D9R467
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

610130:CLOSA RS10355
gene id: 610130:CLOSA_RS10355
uniprot id: D9R182
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

610130:CLOSA RS10545
gene id: 610130:CLOSA_RS10545
uniprot id: D9R1C1
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10925
gene id: 610130:CLOSA_RS10925
uniprot id: D9R294
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19140
gene id: 610130:CLOSA_RS19140
uniprot id: D9R091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05830
gene id: 610130:CLOSA_RS05830
uniprot id: D9R7M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

610130:CLOSA RS18120
gene id: 610130:CLOSA_RS18120
uniprot id: D9RAS8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS09720
gene id: 610130:CLOSA_RS09720
uniprot id: D9R049
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

610130:CLOSA RS15105
gene id: 610130:CLOSA_RS15105
uniprot id: D9R7B6
names: Similarity
messages: Belongs to the archaeal-type GPI family.

610130:CLOSA RS12330
gene id: 610130:CLOSA_RS12330
uniprot id: D9R4E3
names: Similarity
messages: Belongs to the CFA/CMAS family.

610130:CLOSA RS08455
gene id: 610130:CLOSA_RS08455
uniprot id: D9RAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS00225
gene id: 610130:CLOSA_RS00225
uniprot id: D9R0M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

610130:CLOSA RS03040
gene id: 610130:CLOSA_RS03040
uniprot id: D9R4N6
names: Similarity
messages: Belongs to the UPF0751 family.

610130:CLOSA RS04550
gene id: 610130:CLOSA_RS04550
uniprot id: D9R665
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

610130:CLOSA RS18175
gene id: 610130:CLOSA_RS18175
uniprot id: D9RAT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS07450
gene id: 610130:CLOSA_RS07450
uniprot id: D9R9L7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20890
gene id: 610130:CLOSA_RS20890
uniprot id: D9R2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

610130:CLOSA RS13240
gene id: 610130:CLOSA_RS13240
uniprot id: D9R5L1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

610130:CLOSA RS11290
gene id: 610130:CLOSA_RS11290
uniprot id: D9R367
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

610130:CLOSA RS06055
gene id: 610130:CLOSA_RS06055
uniprot id: D9R841
names: Similarity
messages: Belongs to the MT-A70-like family.

610130:CLOSA RS06605
gene id: 610130:CLOSA_RS06605
uniprot id: D9R8E6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS11600
gene id: 610130:CLOSA_RS11600
uniprot id: D9R3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

610130:CLOSA RS11740
gene id: 610130:CLOSA_RS11740
uniprot id: D9R3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02535
gene id: 610130:CLOSA_RS02535
uniprot id: D9R413
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS21415
gene id: 610130:CLOSA_RS21415
uniprot id: D9R3P7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS14960
gene id: 610130:CLOSA_RS14960
uniprot id: D9R788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

610130:CLOSA RS01885
gene id: 610130:CLOSA_RS01885
uniprot id: D9R308
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS18845
gene id: 610130:CLOSA_RS18845
uniprot id: D9QZN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

610130:CLOSA RS16800
gene id: 610130:CLOSA_RS16800
uniprot id: D9R9C5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

610130:CLOSA RS01420
gene id: 610130:CLOSA_RS01420
uniprot id: D9R216
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

610130:CLOSA RS06430
gene id: 610130:CLOSA_RS06430
uniprot id: D9R8B3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

610130:CLOSA RS12010
gene id: 610130:CLOSA_RS12010
uniprot id: D9R481
names: Similarity
messages: Belongs to the CobH/CbiC family.

610130:CLOSA RS07595
gene id: 610130:CLOSA_RS07595
uniprot id: D9R9P6
names: Subcellular Location Annotation
messages: Bacterial microcompartment

610130:CLOSA RS19280
gene id: 610130:CLOSA_RS19280
uniprot id: D9R0C0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07610
gene id: 610130:CLOSA_RS07610
uniprot id: D9R9P9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS00715
gene id: 610130:CLOSA_RS00715
uniprot id: D9R0X7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS04610
gene id: 610130:CLOSA_RS04610
uniprot id: D9R677
names: Similarity
messages: Belongs to the UPF0297 family.

610130:CLOSA RS02970
gene id: 610130:CLOSA_RS02970
uniprot id: D9R4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

610130:CLOSA RS08885
gene id: 610130:CLOSA_RS08885
uniprot id: D9QZ95
names: Similarity
messages: Belongs to the peptidase S14 family.

610130:CLOSA RS00530
gene id: 610130:CLOSA_RS00530
uniprot id: D9R0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS18955
gene id: 610130:CLOSA_RS18955
uniprot id: D9QZR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

610130:CLOSA RS12015
gene id: 610130:CLOSA_RS12015
uniprot id: D9R482
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

610130:CLOSA RS04960
gene id: 610130:CLOSA_RS04960
uniprot id: D9R6S4
names: Similarity
messages: Belongs to the peptidase M13 family.

610130:CLOSA RS01855
gene id: 610130:CLOSA_RS01855
uniprot id: D9R302
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS00275
gene id: 610130:CLOSA_RS00275
uniprot id: D9R0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

610130:CLOSA RS09370
gene id: 610130:CLOSA_RS09370
uniprot id: D9QZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

610130:CLOSA RS06585
gene id: 610130:CLOSA_RS06585
uniprot id: D9R8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS13505
gene id: 610130:CLOSA_RS13505
uniprot id: D9R5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS19565
gene id: 610130:CLOSA_RS19565
uniprot id: D9R0H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

610130:CLOSA RS07585
gene id: 610130:CLOSA_RS07585
uniprot id: D9R9P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

610130:CLOSA RS12190
gene id: 610130:CLOSA_RS12190
uniprot id: D9R4B6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

610130:CLOSA RS09870
gene id: 610130:CLOSA_RS09870
uniprot id: D9R078
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

610130:CLOSA RS11175
gene id: 610130:CLOSA_RS11175
uniprot id: D9R2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

610130:CLOSA RS01895
gene id: 610130:CLOSA_RS01895
uniprot id: D9R310
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

610130:CLOSA RS02790
gene id: 610130:CLOSA_RS02790
uniprot id: D9R4J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS03465
gene id: 610130:CLOSA_RS03465
uniprot id: D9R584
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS11590
gene id: 610130:CLOSA_RS11590
uniprot id: D9R3C0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

610130:CLOSA RS00650
gene id: 610130:CLOSA_RS00650
uniprot id: D9R0W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

610130:CLOSA RS02460
gene id: 610130:CLOSA_RS02460
uniprot id: D9R3Z8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

610130:CLOSA RS08105
gene id: 610130:CLOSA_RS08105
uniprot id: D9RAB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

610130:CLOSA RS08285
gene id: 610130:CLOSA_RS08285
uniprot id: D9RAF3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

610130:CLOSA RS22740
gene id: 610130:CLOSA_RS22740
uniprot id: D9RA15
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

610130:CLOSA RS00485
gene id: 610130:CLOSA_RS00485
uniprot id: D9R0T1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

610130:CLOSA RS09540
gene id: 610130:CLOSA_RS09540
uniprot id: D9R015
names: Similarity
messages: Belongs to the UPF0237 family.

610130:CLOSA RS08230
gene id: 610130:CLOSA_RS08230
uniprot id: D9RAE2
names: Similarity
messages: Belongs to the ArsC family.

610130:CLOSA RS16120
gene id: 610130:CLOSA_RS16120
uniprot id: D9R8L6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

610130:CLOSA RS19250
gene id: 610130:CLOSA_RS19250
uniprot id: D9R0B4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

610130:CLOSA RS03430
gene id: 610130:CLOSA_RS03430
uniprot id: D9R576
names: Similarity
messages: Belongs to the RecJ family.

610130:CLOSA RS20210
gene id: 610130:CLOSA_RS20210
uniprot id: D9R1L5
names: Similarity
messages: Belongs to the thioredoxin family.

610130:CLOSA RS06770
gene id: 610130:CLOSA_RS06770
uniprot id: D9R8V5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06200
gene id: 610130:CLOSA_RS06200
uniprot id: D9R870
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

610130:CLOSA RS14955
gene id: 610130:CLOSA_RS14955
uniprot id: D9R787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

610130:CLOSA RS10010
gene id: 610130:CLOSA_RS10010
uniprot id: D9R111
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

610130:CLOSA RS14345
gene id: 610130:CLOSA_RS14345
uniprot id: D9R6J1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

610130:CLOSA RS02455
gene id: 610130:CLOSA_RS02455
uniprot id: D9R3Z7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

610130:CLOSA RS08740
gene id: 610130:CLOSA_RS08740
uniprot id: D9QZ72
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

610130:CLOSA RS09390
gene id: 610130:CLOSA_RS09390
uniprot id: D9QZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

610130:CLOSA RS10740
gene id: 610130:CLOSA_RS10740
uniprot id: D9R257
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

610130:CLOSA RS08950
gene id: 610130:CLOSA_RS08950
uniprot id: D9QZA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

610130:CLOSA RS15940
gene id: 610130:CLOSA_RS15940
uniprot id: D9R8I4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

610130:CLOSA RS15950
gene id: 610130:CLOSA_RS15950
uniprot id: D9R8I6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

610130:CLOSA RS00450
gene id: 610130:CLOSA_RS00450
uniprot id: D9R0S4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS15395
gene id: 610130:CLOSA_RS15395
uniprot id: D9R7V0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

610130:CLOSA RS05375
gene id: 610130:CLOSA_RS05375
uniprot id: D9R7D2
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

610130:CLOSA RS18810
gene id: 610130:CLOSA_RS18810
uniprot id: D9QZN1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

610130:CLOSA RS14050
gene id: 610130:CLOSA_RS14050
uniprot id: D9R6D2
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS09270
gene id: 610130:CLOSA_RS09270
uniprot id: D9QZW7
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS08965
gene id: 610130:CLOSA_RS08965
uniprot id: D9QZA8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02640
gene id: 610130:CLOSA_RS02640
uniprot id: D9R433
names: Similarity
messages: Belongs to the peptidase C59 family.

610130:CLOSA RS08280
gene id: 610130:CLOSA_RS08280
uniprot id: D9RAF2
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02270
gene id: 610130:CLOSA_RS02270
uniprot id: D9R3W0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

610130:CLOSA RS03585
gene id: 610130:CLOSA_RS03585
uniprot id: D9R5A6
names: Similarity
messages: Belongs to the FBPase class 3 family.

610130:CLOSA RS10275
gene id: 610130:CLOSA_RS10275
uniprot id: D9R165
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

610130:CLOSA RS16385
gene id: 610130:CLOSA_RS16385
uniprot id: D9R8R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

610130:CLOSA RS06335
gene id: 610130:CLOSA_RS06335
uniprot id: D9R895
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18350
gene id: 610130:CLOSA_RS18350
uniprot id: D9RAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05485
gene id: 610130:CLOSA_RS05485
uniprot id: D9R7F4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

610130:CLOSA RS04705
gene id: 610130:CLOSA_RS04705
uniprot id: D9R6M4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18790
gene id: 610130:CLOSA_RS18790
uniprot id: D9QZM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06065
gene id: 610130:CLOSA_RS06065
uniprot id: D9R843
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

610130:CLOSA RS11165
gene id: 610130:CLOSA_RS11165
uniprot id: D9R2D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

610130:CLOSA RS00235
gene id: 610130:CLOSA_RS00235
uniprot id: D9R0N0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

610130:CLOSA RS18410
gene id: 610130:CLOSA_RS18410
uniprot id: D9RAY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS12585
gene id: 610130:CLOSA_RS12585
uniprot id: D9R4V8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10050
gene id: 610130:CLOSA_RS10050
uniprot id: D9R119
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02285
gene id: 610130:CLOSA_RS02285
uniprot id: D9R3W3
names: Similarity
messages: Belongs to the UPF0597 family.

610130:CLOSA RS01770
gene id: 610130:CLOSA_RS01770
uniprot id: D9R2Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS07705
gene id: 610130:CLOSA_RS07705
uniprot id: D9R9R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

610130:CLOSA RS20080
gene id: 610130:CLOSA_RS20080
uniprot id: D9R1I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

610130:CLOSA RS09365
gene id: 610130:CLOSA_RS09365
uniprot id: D9QZY6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS04515
gene id: 610130:CLOSA_RS04515
uniprot id: D9R658
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

610130:CLOSA RS18775
gene id: 610130:CLOSA_RS18775
uniprot id: D9QZM5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS07670
gene id: 610130:CLOSA_RS07670
uniprot id: D9R9R1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

610130:CLOSA RS04290
gene id: 610130:CLOSA_RS04290
uniprot id: D9R616
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS16525
gene id: 610130:CLOSA_RS16525
uniprot id: D9R974
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS03635
gene id: 610130:CLOSA_RS03635
uniprot id: D9R5B6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

610130:CLOSA RS16150
gene id: 610130:CLOSA_RS16150
uniprot id: D9R8M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

610130:CLOSA RS16830
gene id: 610130:CLOSA_RS16830
uniprot id: D9R9D0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

610130:CLOSA RS05240
gene id: 610130:CLOSA_RS05240
uniprot id: D9R6X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

610130:CLOSA RS18325
gene id: 610130:CLOSA_RS18325
uniprot id: D9RAW6
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS06495
gene id: 610130:CLOSA_RS06495
uniprot id: D9R8C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

610130:CLOSA RS15240
gene id: 610130:CLOSA_RS15240
uniprot id: D9R7S1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

610130:CLOSA RS21175
gene id: 610130:CLOSA_RS21175
uniprot id: D9R3K1
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS04210
gene id: 610130:CLOSA_RS04210
uniprot id: D9R600
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

610130:CLOSA RS03380
gene id: 610130:CLOSA_RS03380
uniprot id: D9R4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS17380
gene id: 610130:CLOSA_RS17380
uniprot id: D9RA09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

610130:CLOSA RS10560
gene id: 610130:CLOSA_RS10560
uniprot id: D9R221
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS14040
gene id: 610130:CLOSA_RS14040
uniprot id: D9R6D0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS02935
gene id: 610130:CLOSA_RS02935
uniprot id: D9R4L5
names: Similarity
messages: Belongs to the TPP enzyme family.

610130:CLOSA RS01660
gene id: 610130:CLOSA_RS01660
uniprot id: D9R2W5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS19585
gene id: 610130:CLOSA_RS19585
uniprot id: D9R0I1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

610130:CLOSA RS09315
gene id: 610130:CLOSA_RS09315
uniprot id: D9QZX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

610130:CLOSA RS16435
gene id: 610130:CLOSA_RS16435
uniprot id: D9R8S8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS06670
gene id: 610130:CLOSA_RS06670
uniprot id: D9R8T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

610130:CLOSA RS06660
gene id: 610130:CLOSA_RS06660
uniprot id: D9R8T4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

610130:CLOSA RS09340
gene id: 610130:CLOSA_RS09340
uniprot id: D9QZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS01700
gene id: 610130:CLOSA_RS01700
uniprot id: D9R2X1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

610130:CLOSA RS06340
gene id: 610130:CLOSA_RS06340
uniprot id: D9R896
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10020
gene id: 610130:CLOSA_RS10020
uniprot id: D9R113
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

610130:CLOSA RS08275
gene id: 610130:CLOSA_RS08275
uniprot id: D9RAF1
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS01690
gene id: 610130:CLOSA_RS01690
uniprot id: D9R2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

610130:CLOSA RS21975
gene id: 610130:CLOSA_RS21975
uniprot id: D9R0J5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS13480
gene id: 610130:CLOSA_RS13480
uniprot id: D9R5Q5
names: Similarity
messages: Belongs to the UPF0178 family.

610130:CLOSA RS09545
gene id: 610130:CLOSA_RS09545
uniprot id: D9R016
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

610130:CLOSA RS10260
gene id: 610130:CLOSA_RS10260
uniprot id: D9R162
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

610130:CLOSA RS03535
gene id: 610130:CLOSA_RS03535
uniprot id: D9R596
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

610130:CLOSA RS17235
gene id: 610130:CLOSA_RS17235
uniprot id: D9R9Y0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

610130:CLOSA RS01240
gene id: 610130:CLOSA_RS01240
uniprot id: D9R1Y0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

610130:CLOSA RS21405
gene id: 610130:CLOSA_RS21405
uniprot id: D9R3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS00245
gene id: 610130:CLOSA_RS00245
uniprot id: D9R0N2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

610130:CLOSA RS03435
gene id: 610130:CLOSA_RS03435
uniprot id: D9R577
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS06440
gene id: 610130:CLOSA_RS06440
uniprot id: D9R8B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

610130:CLOSA RS01385
gene id: 610130:CLOSA_RS01385
uniprot id: D9R209
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

610130:CLOSA RS07725
gene id: 610130:CLOSA_RS07725
uniprot id: D9R9S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

610130:CLOSA RS12030
gene id: 610130:CLOSA_RS12030
uniprot id: D9R485
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

610130:CLOSA RS14510
gene id: 610130:CLOSA_RS14510
uniprot id: D9R700
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

610130:CLOSA RS10110
gene id: 610130:CLOSA_RS10110
uniprot id: D9R132
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

610130:CLOSA RS01820
gene id: 610130:CLOSA_RS01820
uniprot id: D9R2Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

610130:CLOSA RS18765
gene id: 610130:CLOSA_RS18765
uniprot id: D9QZM3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

610130:CLOSA RS11560
gene id: 610130:CLOSA_RS11560
uniprot id: D9R3B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

610130:CLOSA RS17365
gene id: 610130:CLOSA_RS17365
uniprot id: D9RA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

610130:CLOSA RS08155
gene id: 610130:CLOSA_RS08155
uniprot id: D9RAC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS02625
gene id: 610130:CLOSA_RS02625
uniprot id: D9R431
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

610130:CLOSA RS11695
gene id: 610130:CLOSA_RS11695
uniprot id: D9R3E0
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

610130:CLOSA RS09900
gene id: 610130:CLOSA_RS09900
uniprot id: D9R085
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

610130:CLOSA RS16095
gene id: 610130:CLOSA_RS16095
uniprot id: D9R8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15260
gene id: 610130:CLOSA_RS15260
uniprot id: D9R7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS19310
gene id: 610130:CLOSA_RS19310
uniprot id: D9R0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

610130:CLOSA RS08370
gene id: 610130:CLOSA_RS08370
uniprot id: D9RAG9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

610130:CLOSA RS02595
gene id: 610130:CLOSA_RS02595
uniprot id: D9R425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15475
gene id: 610130:CLOSA_RS15475
uniprot id: D9R7W6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS21760
gene id: 610130:CLOSA_RS21760
uniprot id: D9R4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS10695
gene id: 610130:CLOSA_RS10695
uniprot id: D9R248
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

610130:CLOSA RS07805
gene id: 610130:CLOSA_RS07805
uniprot id: D9R9T8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

610130:CLOSA RS10730
gene id: 610130:CLOSA_RS10730
uniprot id: D9R255
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

610130:CLOSA RS08710
gene id: 610130:CLOSA_RS08710
uniprot id: D9QZ65
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

610130:CLOSA RS19925
gene id: 610130:CLOSA_RS19925
uniprot id: D9R1F9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS16445
gene id: 610130:CLOSA_RS16445
uniprot id: D9R8T0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

610130:CLOSA RS00665
gene id: 610130:CLOSA_RS00665
uniprot id: D9R0W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

610130:CLOSA RS01220
gene id: 610130:CLOSA_RS01220
uniprot id: D9R1X6
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18210
gene id: 610130:CLOSA_RS18210
uniprot id: D9RAU4
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Homodimer.

610130:CLOSA RS10920
gene id: 610130:CLOSA_RS10920
uniprot id: D9R293
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS16620
gene id: 610130:CLOSA_RS16620
uniprot id: D9R992
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

610130:CLOSA RS18860
gene id: 610130:CLOSA_RS18860
uniprot id: D9QZP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

610130:CLOSA RS04580
gene id: 610130:CLOSA_RS04580
uniprot id: D9R671
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

610130:CLOSA RS04895
gene id: 610130:CLOSA_RS04895
uniprot id: D9R6R2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS03440
gene id: 610130:CLOSA_RS03440
uniprot id: D9R579
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

610130:CLOSA RS18245
gene id: 610130:CLOSA_RS18245
uniprot id: D9RAV0
names: Similarity
messages: Belongs to the TrpF family.

610130:CLOSA RS07520
gene id: 610130:CLOSA_RS07520
uniprot id: D9R9N1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

610130:CLOSA RS06245
gene id: 610130:CLOSA_RS06245
uniprot id: D9R879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10415
gene id: 610130:CLOSA_RS10415
uniprot id: D9R194
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS13440
gene id: 610130:CLOSA_RS13440
uniprot id: D9R5P7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

610130:CLOSA RS00030
gene id: 610130:CLOSA_RS00030
uniprot id: D9QZV0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

610130:CLOSA RS16210
gene id: 610130:CLOSA_RS16210
uniprot id: D9R8N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

610130:CLOSA RS04915
gene id: 610130:CLOSA_RS04915
uniprot id: D9R6R6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

610130:CLOSA RS16770
gene id: 610130:CLOSA_RS16770
uniprot id: D9R9C1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS16470
gene id: 610130:CLOSA_RS16470
uniprot id: D9R963
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

610130:CLOSA RS09125
gene id: 610130:CLOSA_RS09125
uniprot id: D9QZD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

610130:CLOSA RS09335
gene id: 610130:CLOSA_RS09335
uniprot id: D9QZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02995
gene id: 610130:CLOSA_RS02995
uniprot id: D9R4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS03165
gene id: 610130:CLOSA_RS03165
uniprot id: D9R4R1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

610130:CLOSA RS02160
gene id: 610130:CLOSA_RS02160
uniprot id: D9R3T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

610130:CLOSA RS10580
gene id: 610130:CLOSA_RS10580
uniprot id: D9R225
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

610130:CLOSA RS11770
gene id: 610130:CLOSA_RS11770
uniprot id: D9R3F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

610130:CLOSA RS21355
gene id: 610130:CLOSA_RS21355
uniprot id: D9R3N6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS11810
gene id: 610130:CLOSA_RS11810
uniprot id: D9R3G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS19495
gene id: 610130:CLOSA_RS19495
uniprot id: D9R0G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS01590
gene id: 610130:CLOSA_RS01590
uniprot id: D9R2V0
names: Similarity
messages: Belongs to the ParB family.

610130:CLOSA RS03540
gene id: 610130:CLOSA_RS03540
uniprot id: D9R597
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

610130:CLOSA RS19055
gene id: 610130:CLOSA_RS19055
uniprot id: D9QZT1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

610130:CLOSA RS06590
gene id: 610130:CLOSA_RS06590
uniprot id: D9R8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11715
gene id: 610130:CLOSA_RS11715
uniprot id: D9R3E4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS17385
gene id: 610130:CLOSA_RS17385
uniprot id: D9RA10
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS08355
gene id: 610130:CLOSA_RS08355
uniprot id: D9RAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

610130:CLOSA RS09180
gene id: 610130:CLOSA_RS09180
uniprot id: D9QZE8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

610130:CLOSA RS21960
gene id: 610130:CLOSA_RS21960
uniprot id: D9R0F7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02405
gene id: 610130:CLOSA_RS02405
uniprot id: D9R3Y7
names: Similarity
messages: Belongs to the threonine synthase family.

610130:CLOSA RS20530
gene id: 610130:CLOSA_RS20530
uniprot id: D9R2H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS21135
gene id: 610130:CLOSA_RS21135
uniprot id: D9R3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS08735
gene id: 610130:CLOSA_RS08735
uniprot id: D9QZ71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS20640
gene id: 610130:CLOSA_RS20640
uniprot id: D9R2J3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

610130:CLOSA RS15975
gene id: 610130:CLOSA_RS15975
uniprot id: D9R8J1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

610130:CLOSA RS10500
gene id: 610130:CLOSA_RS10500
uniprot id: D9R1B2
names: Similarity
messages: Belongs to the FGGY kinase family.

610130:CLOSA RS14795
gene id: 610130:CLOSA_RS14795
uniprot id: D9R755
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

610130:CLOSA RS09210
gene id: 610130:CLOSA_RS09210
uniprot id: D9QZF4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS01785
gene id: 610130:CLOSA_RS01785
uniprot id: D9R2Y8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

610130:CLOSA RS03500
gene id: 610130:CLOSA_RS03500
uniprot id: D9R590
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

610130:CLOSA RS11940
gene id: 610130:CLOSA_RS11940
uniprot id: D9R468
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

610130:CLOSA RS14970
gene id: 610130:CLOSA_RS14970
uniprot id: D9R790
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09110
gene id: 610130:CLOSA_RS09110
uniprot id: D9QZD4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

610130:CLOSA RS12415
gene id: 610130:CLOSA_RS12415
uniprot id: D9R4F9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS04155
gene id: 610130:CLOSA_RS04155
uniprot id: D9R5Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

610130:CLOSA RS18870
gene id: 610130:CLOSA_RS18870
uniprot id: D9QZP4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

610130:CLOSA RS10120
gene id: 610130:CLOSA_RS10120
uniprot id: D9R134
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

610130:CLOSA RS16190
gene id: 610130:CLOSA_RS16190
uniprot id: D9R8N0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS10655
gene id: 610130:CLOSA_RS10655
uniprot id: D9R240
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

610130:CLOSA RS13035
gene id: 610130:CLOSA_RS13035
uniprot id: D9R546
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS17500
gene id: 610130:CLOSA_RS17500
uniprot id: D9RA32
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

610130:CLOSA RS18065
gene id: 610130:CLOSA_RS18065
uniprot id: D9RAR7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

610130:CLOSA RS20515
gene id: 610130:CLOSA_RS20515
uniprot id: D9R2G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS12475
gene id: 610130:CLOSA_RS12475
uniprot id: D9R4H1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS10175
gene id: 610130:CLOSA_RS10175
uniprot id: D9R145
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

610130:CLOSA RS12540
gene id: 610130:CLOSA_RS12540
uniprot id: D9R4U9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

610130:CLOSA RS07975
gene id: 610130:CLOSA_RS07975
uniprot id: D9RA92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

610130:CLOSA RS01965
gene id: 610130:CLOSA_RS01965
uniprot id: D9R321
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

610130:CLOSA RS12940
gene id: 610130:CLOSA_RS12940
uniprot id: D9R528
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02155
gene id: 610130:CLOSA_RS02155
uniprot id: D9R3T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

610130:CLOSA RS18180
gene id: 610130:CLOSA_RS18180
uniprot id: D9RAT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

610130:CLOSA RS02715
gene id: 610130:CLOSA_RS02715
uniprot id: D9R448
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

610130:CLOSA RS15465
gene id: 610130:CLOSA_RS15465
uniprot id: D9R7W4
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

610130:CLOSA RS10185
gene id: 610130:CLOSA_RS10185
uniprot id: D9R147
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

610130:CLOSA RS21075
gene id: 610130:CLOSA_RS21075
uniprot id: D9R3I1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

610130:CLOSA RS05000
gene id: 610130:CLOSA_RS05000
uniprot id: D9R6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06030
gene id: 610130:CLOSA_RS06030
uniprot id: D9R836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10825
gene id: 610130:CLOSA_RS10825
uniprot id: D9R274
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS16825
gene id: 610130:CLOSA_RS16825
uniprot id: D9R9C9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

610130:CLOSA RS04490
gene id: 610130:CLOSA_RS04490
uniprot id: D9R653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10220
gene id: 610130:CLOSA_RS10220
uniprot id: D9R154
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS20760
gene id: 610130:CLOSA_RS20760
uniprot id: D9R2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05410
gene id: 610130:CLOSA_RS05410
uniprot id: D9R7D9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02065
gene id: 610130:CLOSA_RS02065
uniprot id: D9R341
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS01130
gene id: 610130:CLOSA_RS01130
uniprot id: D9R1V8
names: Similarity
messages: Belongs to the DtxR/MntR family.

610130:CLOSA RS00800
gene id: 610130:CLOSA_RS00800
uniprot id: D9R1Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS04615
gene id: 610130:CLOSA_RS04615
uniprot id: D9R678
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

610130:CLOSA RS01915
gene id: 610130:CLOSA_RS01915
uniprot id: D9R314
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

610130:CLOSA RS14710
gene id: 610130:CLOSA_RS14710
uniprot id: D9R738
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

610130:CLOSA RS20885
gene id: 610130:CLOSA_RS20885
uniprot id: D9R2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

610130:CLOSA RS01720
gene id: 610130:CLOSA_RS01720
uniprot id: D9R2X5
names: Similarity
messages: Belongs to the MecA family.

610130:CLOSA RS16325
gene id: 610130:CLOSA_RS16325
uniprot id: D9R8Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

610130:CLOSA RS16170
gene id: 610130:CLOSA_RS16170
uniprot id: D9R8M6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

610130:CLOSA RS18895
gene id: 610130:CLOSA_RS18895
uniprot id: D9QZP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

610130:CLOSA RS01920
gene id: 610130:CLOSA_RS01920
uniprot id: D9R315
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

610130:CLOSA RS08345
gene id: 610130:CLOSA_RS08345
uniprot id: D9RAG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

610130:CLOSA RS04620
gene id: 610130:CLOSA_RS04620
uniprot id: D9R679
names: Similarity
messages: Belongs to the UPF0473 family.

610130:CLOSA RS00785
gene id: 610130:CLOSA_RS00785
uniprot id: D9R0Z1
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS05040
gene id: 610130:CLOSA_RS05040
uniprot id: D9R6T8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS21530
gene id: 610130:CLOSA_RS21530
uniprot id: D9R3R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

610130:CLOSA RS07340
gene id: 610130:CLOSA_RS07340
uniprot id: D9R9J5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

610130:CLOSA RS17295
gene id: 610130:CLOSA_RS17295
uniprot id: D9R9Z2
names: Similarity
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.

610130:CLOSA RS04690
gene id: 610130:CLOSA_RS04690
uniprot id: D9R6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS11720
gene id: 610130:CLOSA_RS11720
uniprot id: D9R3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

610130:CLOSA RS07505
gene id: 610130:CLOSA_RS07505
uniprot id: D9R9M8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS05075
gene id: 610130:CLOSA_RS05075
uniprot id: D9R6U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS20710
gene id: 610130:CLOSA_RS20710
uniprot id: D9R2K5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

610130:CLOSA RS20470
gene id: 610130:CLOSA_RS20470
uniprot id: D9R2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

610130:CLOSA RS19555
gene id: 610130:CLOSA_RS19555
uniprot id: D9R0H5
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

610130:CLOSA RS17095
gene id: 610130:CLOSA_RS17095
uniprot id: D9R9I5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

610130:CLOSA RS21130
gene id: 610130:CLOSA_RS21130
uniprot id: D9R3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09480
gene id: 610130:CLOSA_RS09480
uniprot id: D9R004
names: Similarity
messages: Belongs to the aldose epimerase family.

610130:CLOSA RS06805
gene id: 610130:CLOSA_RS06805
uniprot id: D9R8W2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

610130:CLOSA RS11035
gene id: 610130:CLOSA_RS11035
uniprot id: D9R2B3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

610130:CLOSA RS00025
gene id: 610130:CLOSA_RS00025
uniprot id: D9QZU9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

610130:CLOSA RS19145
gene id: 610130:CLOSA_RS19145
uniprot id: D9R092
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

610130:CLOSA RS10025
gene id: 610130:CLOSA_RS10025
uniprot id: D9R114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

610130:CLOSA RS16540
gene id: 610130:CLOSA_RS16540
uniprot id: D9R977
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

610130:CLOSA RS20005
gene id: 610130:CLOSA_RS20005
uniprot id: D9R1H5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

610130:CLOSA RS12335
gene id: 610130:CLOSA_RS12335
uniprot id: D9R4E4
names: Similarity
messages: Belongs to the EamA transporter family.

610130:CLOSA RS09500
gene id: 610130:CLOSA_RS09500
uniprot id: D9R008
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19730
gene id: 610130:CLOSA_RS19730
uniprot id: D9R0L2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

610130:CLOSA RS21150
gene id: 610130:CLOSA_RS21150
uniprot id: D9R3J6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS10015
gene id: 610130:CLOSA_RS10015
uniprot id: D9R112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

610130:CLOSA RS21475
gene id: 610130:CLOSA_RS21475
uniprot id: D9R3Q8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

610130:CLOSA RS19770
gene id: 610130:CLOSA_RS19770
uniprot id: D9R1D0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

610130:CLOSA RS04740
gene id: 610130:CLOSA_RS04740
uniprot id: D9R6N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

610130:CLOSA RS11390
gene id: 610130:CLOSA_RS11390
uniprot id: D9R386
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS06370
gene id: 610130:CLOSA_RS06370
uniprot id: D9R8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

610130:CLOSA RS15410
gene id: 610130:CLOSA_RS15410
uniprot id: D9R7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

610130:CLOSA RS11735
gene id: 610130:CLOSA_RS11735
uniprot id: D9R3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS16700
gene id: 610130:CLOSA_RS16700
uniprot id: D9R9A8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18885
gene id: 610130:CLOSA_RS18885
uniprot id: D9QZP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

610130:CLOSA RS20195
gene id: 610130:CLOSA_RS20195
uniprot id: D9R1L2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS20085
gene id: 610130:CLOSA_RS20085
uniprot id: D9R1J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

610130:CLOSA RS09575
gene id: 610130:CLOSA_RS09575
uniprot id: D9R022
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

610130:CLOSA RS10445
gene id: 610130:CLOSA_RS10445
uniprot id: D9R1A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

610130:CLOSA RS19275
gene id: 610130:CLOSA_RS19275
uniprot id: D9R0B9
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

610130:CLOSA RS08705
gene id: 610130:CLOSA_RS08705
uniprot id: D9QZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS20050
gene id: 610130:CLOSA_RS20050
uniprot id: D9R1I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

610130:CLOSA RS20135
gene id: 610130:CLOSA_RS20135
uniprot id: D9R1K0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

610130:CLOSA RS10525
gene id: 610130:CLOSA_RS10525
uniprot id: D9R1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS20950
gene id: 610130:CLOSA_RS20950
uniprot id: D9R2Q4
names: Similarity
messages: Belongs to the Fur family.

610130:CLOSA RS05480
gene id: 610130:CLOSA_RS05480
uniprot id: D9R7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

610130:CLOSA RS16630
gene id: 610130:CLOSA_RS16630
uniprot id: D9R994
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

610130:CLOSA RS15750
gene id: 610130:CLOSA_RS15750
uniprot id: D9R820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

610130:CLOSA RS11985
gene id: 610130:CLOSA_RS11985
uniprot id: D9R476
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

610130:CLOSA RS03770
gene id: 610130:CLOSA_RS03770
uniprot id: D9R5E1
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

610130:CLOSA RS17185
gene id: 610130:CLOSA_RS17185
uniprot id: D9R9X0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS20730
gene id: 610130:CLOSA_RS20730
uniprot id: D9R2K9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS16795
gene id: 610130:CLOSA_RS16795
uniprot id: D9R9C4
names: Similarity
messages: Belongs to the DtxR/MntR family.

610130:CLOSA RS08540
gene id: 610130:CLOSA_RS08540
uniprot id: D9RAK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS21185
gene id: 610130:CLOSA_RS21185
uniprot id: D9R3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS18235
gene id: 610130:CLOSA_RS18235
uniprot id: D9RAU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS17065
gene id: 610130:CLOSA_RS17065
uniprot id: D9R9H9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

610130:CLOSA RS19725
gene id: 610130:CLOSA_RS19725
uniprot id: D9R0L1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

610130:CLOSA RS12710
gene id: 610130:CLOSA_RS12710
uniprot id: D9R4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

610130:CLOSA RS20495
gene id: 610130:CLOSA_RS20495
uniprot id: D9R2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11080
gene id: 610130:CLOSA_RS11080
uniprot id: D9R2C2
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS12630
gene id: 610130:CLOSA_RS12630
uniprot id: D9R4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

610130:CLOSA RS09820
gene id: 610130:CLOSA_RS09820
uniprot id: D9R068
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS05305
gene id: 610130:CLOSA_RS05305
uniprot id: D9R6Z1
names: Similarity
messages: Belongs to the carbamate kinase family.

610130:CLOSA RS16835
gene id: 610130:CLOSA_RS16835
uniprot id: D9R9D1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

610130:CLOSA RS19040
gene id: 610130:CLOSA_RS19040
uniprot id: D9QZS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

610130:CLOSA RS18250
gene id: 610130:CLOSA_RS18250
uniprot id: D9RAV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

610130:CLOSA RS11500
gene id: 610130:CLOSA_RS11500
uniprot id: D9R3A7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS05805
gene id: 610130:CLOSA_RS05805
uniprot id: D9R7L8
names: Similarity
messages: Belongs to the NDK family.

610130:CLOSA RS20945
gene id: 610130:CLOSA_RS20945
uniprot id: D9R2Q3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

610130:CLOSA RS04115
gene id: 610130:CLOSA_RS04115
uniprot id: D9R5Y4
names: Similarity
messages: Belongs to the CdaR family.

610130:CLOSA RS19255
gene id: 610130:CLOSA_RS19255
uniprot id: D9R0B5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

610130:CLOSA RS04305
gene id: 610130:CLOSA_RS04305
uniprot id: D9R619
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

610130:CLOSA RS18825
gene id: 610130:CLOSA_RS18825
uniprot id: D9QZN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

610130:CLOSA RS02435
gene id: 610130:CLOSA_RS02435
uniprot id: D9R3Z3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

610130:CLOSA RS00335
gene id: 610130:CLOSA_RS00335
uniprot id: D9R0Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS14980
gene id: 610130:CLOSA_RS14980
uniprot id: D9R792
names: Similarity
messages: Belongs to the phosphohexose mutase family.

610130:CLOSA RS00660
gene id: 610130:CLOSA_RS00660
uniprot id: D9R0W6
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

610130:CLOSA RS02125
gene id: 610130:CLOSA_RS02125
uniprot id: D9R3T0
names: Function
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

610130:CLOSA RS20725
gene id: 610130:CLOSA_RS20725
uniprot id: D9R2K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

610130:CLOSA RS08510
gene id: 610130:CLOSA_RS08510
uniprot id: D9RAJ7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20115
gene id: 610130:CLOSA_RS20115
uniprot id: D9R1J6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS12000
gene id: 610130:CLOSA_RS12000
uniprot id: D9R479
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07410
gene id: 610130:CLOSA_RS07410
uniprot id: D9R9K9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS04715
gene id: 610130:CLOSA_RS04715
uniprot id: D9R6M6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

610130:CLOSA RS15275
gene id: 610130:CLOSA_RS15275
uniprot id: D9R7S8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

610130:CLOSA RS19735
gene id: 610130:CLOSA_RS19735
uniprot id: D9R0L3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

610130:CLOSA RS02145
gene id: 610130:CLOSA_RS02145
uniprot id: D9R3T4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

610130:CLOSA RS00260
gene id: 610130:CLOSA_RS00260
uniprot id: D9R0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

610130:CLOSA RS12375
gene id: 610130:CLOSA_RS12375
uniprot id: D9R4F1
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

610130:CLOSA RS21110
gene id: 610130:CLOSA_RS21110
uniprot id: D9R3I8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS06480
gene id: 610130:CLOSA_RS06480
uniprot id: D9R8C3
names: Similarity
messages: Belongs to the glutamine synthetase family.

610130:CLOSA RS01990
gene id: 610130:CLOSA_RS01990
uniprot id: D9R326
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

610130:CLOSA RS07500
gene id: 610130:CLOSA_RS07500
uniprot id: D9R9M7
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS20615
gene id: 610130:CLOSA_RS20615
uniprot id: D9R2I8
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

610130:CLOSA RS18865
gene id: 610130:CLOSA_RS18865
uniprot id: D9QZP3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

610130:CLOSA RS11470
gene id: 610130:CLOSA_RS11470
uniprot id: D9R3A2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

610130:CLOSA RS03330
gene id: 610130:CLOSA_RS03330
uniprot id: D9R4S8
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

610130:CLOSA RS21860
gene id: 610130:CLOSA_RS21860
uniprot id: D9R8Q3
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS07840
gene id: 610130:CLOSA_RS07840
uniprot id: D9R9U5
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS06415
gene id: 610130:CLOSA_RS06415
uniprot id: D9R8B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS20360
gene id: 610130:CLOSA_RS20360
uniprot id: D9R1P0
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

610130:CLOSA RS09490
gene id: 610130:CLOSA_RS09490
uniprot id: D9R006
names: Similarity
messages: Belongs to the type IA topoisomerase family.

610130:CLOSA RS14170
gene id: 610130:CLOSA_RS14170
uniprot id: D9R6F8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS11990
gene id: 610130:CLOSA_RS11990
uniprot id: D9R477
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

610130:CLOSA RS13820
gene id: 610130:CLOSA_RS13820
uniprot id: D9R5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05530
gene id: 610130:CLOSA_RS05530
uniprot id: D9R7G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

610130:CLOSA RS04765
gene id: 610130:CLOSA_RS04765
uniprot id: D9R6N6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS19400
gene id: 610130:CLOSA_RS19400
uniprot id: D9R0E4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

610130:CLOSA RS00425
gene id: 610130:CLOSA_RS00425
uniprot id: D9R0R8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

610130:CLOSA RS07710
gene id: 610130:CLOSA_RS07710
uniprot id: D9R9S0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

610130:CLOSA RS12055
gene id: 610130:CLOSA_RS12055
uniprot id: D9R490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS14145
gene id: 610130:CLOSA_RS14145
uniprot id: D9R6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

610130:CLOSA RS05045
gene id: 610130:CLOSA_RS05045
uniprot id: D9R6T9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS01405
gene id: 610130:CLOSA_RS01405
uniprot id: D9R213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15285
gene id: 610130:CLOSA_RS15285
uniprot id: D9R7T0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19970
gene id: 610130:CLOSA_RS19970
uniprot id: D9R1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10570
gene id: 610130:CLOSA_RS10570
uniprot id: D9R223
names: Similarity
messages: Belongs to the leucine-binding protein family.

610130:CLOSA RS05310
gene id: 610130:CLOSA_RS05310
uniprot id: D9R6Z2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

610130:CLOSA RS04240
gene id: 610130:CLOSA_RS04240
uniprot id: D9R606
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

610130:CLOSA RS15225
gene id: 610130:CLOSA_RS15225
uniprot id: D9R7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

610130:CLOSA RS05600
gene id: 610130:CLOSA_RS05600
uniprot id: D9R7H7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS18275
gene id: 610130:CLOSA_RS18275
uniprot id: D9RAV6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

610130:CLOSA RS12875
gene id: 610130:CLOSA_RS12875
uniprot id: D9R515
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

610130:CLOSA RS10330
gene id: 610130:CLOSA_RS10330
uniprot id: D9R176
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

610130:CLOSA RS09710
gene id: 610130:CLOSA_RS09710
uniprot id: D9R047
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

610130:CLOSA RS07750
gene id: 610130:CLOSA_RS07750
uniprot id: D9R9S8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

610130:CLOSA RS01710
gene id: 610130:CLOSA_RS01710
uniprot id: D9R2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

610130:CLOSA RS08090
gene id: 610130:CLOSA_RS08090
uniprot id: D9RAB5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

610130:CLOSA RS01095
gene id: 610130:CLOSA_RS01095
uniprot id: D9R1V1
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS17010
gene id: 610130:CLOSA_RS17010
uniprot id: D9R9G6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

610130:CLOSA RS11875
gene id: 610130:CLOSA_RS11875
uniprot id: D9R455
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

610130:CLOSA RS21170
gene id: 610130:CLOSA_RS21170
uniprot id: D9R3K0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS12410
gene id: 610130:CLOSA_RS12410
uniprot id: D9R4F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS08655
gene id: 610130:CLOSA_RS08655
uniprot id: D9QZ54
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20490
gene id: 610130:CLOSA_RS20490
uniprot id: D9R2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10830
gene id: 610130:CLOSA_RS10830
uniprot id: D9R275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

610130:CLOSA RS15175
gene id: 610130:CLOSA_RS15175
uniprot id: D9R7Q8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS00525
gene id: 610130:CLOSA_RS00525
uniprot id: D9R0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10765
gene id: 610130:CLOSA_RS10765
uniprot id: D9R262
names: Similarity
messages: Belongs to the citrate synthase family.

610130:CLOSA RS00230
gene id: 610130:CLOSA_RS00230
uniprot id: D9R0M9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

610130:CLOSA RS02035
gene id: 610130:CLOSA_RS02035
uniprot id: D9R335
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS06410
gene id: 610130:CLOSA_RS06410
uniprot id: D9R8A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

610130:CLOSA RS20240
gene id: 610130:CLOSA_RS20240
uniprot id: D9R1M1
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS13470
gene id: 610130:CLOSA_RS13470
uniprot id: D9R5Q3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

610130:CLOSA RS21430
gene id: 610130:CLOSA_RS21430
uniprot id: D9R3Q0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07600
gene id: 610130:CLOSA_RS07600
uniprot id: D9R9P7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS13150
gene id: 610130:CLOSA_RS13150
uniprot id: D9R569
names: Similarity
messages: Belongs to the HypD family.

610130:CLOSA RS19315
gene id: 610130:CLOSA_RS19315
uniprot id: D9R0C6
names: Similarity
messages: Belongs to the TelA family.

610130:CLOSA RS04535
gene id: 610130:CLOSA_RS04535
uniprot id: D9R662
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

610130:CLOSA RS06425
gene id: 610130:CLOSA_RS06425
uniprot id: D9R8B2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

610130:CLOSA RS20245
gene id: 610130:CLOSA_RS20245
uniprot id: D9R1M2
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS00810
gene id: 610130:CLOSA_RS00810
uniprot id: D9R1Q4
names: Similarity
messages: Belongs to the ArsC family.

610130:CLOSA RS12995
gene id: 610130:CLOSA_RS12995
uniprot id: D9R538
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

610130:CLOSA RS05970
gene id: 610130:CLOSA_RS05970
uniprot id: D9R7P7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

610130:CLOSA RS01800
gene id: 610130:CLOSA_RS01800
uniprot id: D9R2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

610130:CLOSA RS07895
gene id: 610130:CLOSA_RS07895
uniprot id: D9R9V3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

610130:CLOSA RS00410
gene id: 610130:CLOSA_RS00410
uniprot id: D9R0R6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

610130:CLOSA RS10305
gene id: 610130:CLOSA_RS10305
uniprot id: D9R171
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

610130:CLOSA RS15970
gene id: 610130:CLOSA_RS15970
uniprot id: D9R8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS19960
gene id: 610130:CLOSA_RS19960
uniprot id: D9R1G6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

610130:CLOSA RS13155
gene id: 610130:CLOSA_RS13155
uniprot id: D9R570
names: Similarity
messages: Belongs to the HupF/HypC family.

610130:CLOSA RS20775
gene id: 610130:CLOSA_RS20775
uniprot id: D9R2L8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS02140
gene id: 610130:CLOSA_RS02140
uniprot id: D9R3T3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

610130:CLOSA RS08050
gene id: 610130:CLOSA_RS08050
uniprot id: D9RAA7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

610130:CLOSA RS06680
gene id: 610130:CLOSA_RS06680
uniprot id: D9R8T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS18445
gene id: 610130:CLOSA_RS18445
uniprot id: D9RAY9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

610130:CLOSA RS00900
gene id: 610130:CLOSA_RS00900
uniprot id: D9R1S1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS17555
gene id: 610130:CLOSA_RS17555
uniprot id: D9RA43
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

610130:CLOSA RS16865
gene id: 610130:CLOSA_RS16865
uniprot id: D9R9D7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18460
gene id: 610130:CLOSA_RS18460
uniprot id: D9RAZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS09310
gene id: 610130:CLOSA_RS09310
uniprot id: D9QZX5
names: Similarity
messages: Belongs to the DprA/Smf family.

610130:CLOSA RS19830
gene id: 610130:CLOSA_RS19830
uniprot id: D9R1E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS04575
gene id: 610130:CLOSA_RS04575
uniprot id: D9R670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06275
gene id: 610130:CLOSA_RS06275
uniprot id: D9R885
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

610130:CLOSA RS12250
gene id: 610130:CLOSA_RS12250
uniprot id: D9R4C8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

610130:CLOSA RS19720
gene id: 610130:CLOSA_RS19720
uniprot id: D9R0K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

610130:CLOSA RS21220
gene id: 610130:CLOSA_RS21220
uniprot id: D9R3L0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS07955
gene id: 610130:CLOSA_RS07955
uniprot id: D9RA88
names: Similarity
messages: Belongs to the IMPACT family.

610130:CLOSA RS00710
gene id: 610130:CLOSA_RS00710
uniprot id: D9R0X6
names: Similarity
messages: Belongs to the GSP E family.

610130:CLOSA RS03550
gene id: 610130:CLOSA_RS03550
uniprot id: D9R599
names: Similarity
messages: Belongs to the peptidase S11 family.

610130:CLOSA RS04295
gene id: 610130:CLOSA_RS04295
uniprot id: D9R617
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

610130:CLOSA RS10100
gene id: 610130:CLOSA_RS10100
uniprot id: D9R130
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS21510
gene id: 610130:CLOSA_RS21510
uniprot id: D9R3R5
names: Similarity
messages: Belongs to the ParB family.

610130:CLOSA RS02090
gene id: 610130:CLOSA_RS02090
uniprot id: D9R346
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

610130:CLOSA RS06035
gene id: 610130:CLOSA_RS06035
uniprot id: D9R837
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS21900
gene id: 610130:CLOSA_RS21900
uniprot id: D9RA17
names: Similarity
messages: Belongs to the FlgD family.

610130:CLOSA RS10360
gene id: 610130:CLOSA_RS10360
uniprot id: D9R183
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

610130:CLOSA RS04260
gene id: 610130:CLOSA_RS04260
uniprot id: D9R610
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19185
gene id: 610130:CLOSA_RS19185
uniprot id: D9R0A1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS21330
gene id: 610130:CLOSA_RS21330
uniprot id: D9R3N1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

610130:CLOSA RS06715
gene id: 610130:CLOSA_RS06715
uniprot id: D9R8U4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

610130:CLOSA RS18095
gene id: 610130:CLOSA_RS18095
uniprot id: D9RAS3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

610130:CLOSA RS08650
gene id: 610130:CLOSA_RS08650
uniprot id: D9QZ53
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

610130:CLOSA RS08525
gene id: 610130:CLOSA_RS08525
uniprot id: D9RAK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

610130:CLOSA RS05170
gene id: 610130:CLOSA_RS05170
uniprot id: D9R6W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

610130:CLOSA RS11670
gene id: 610130:CLOSA_RS11670
uniprot id: D9R3D7
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

610130:CLOSA RS16265
gene id: 610130:CLOSA_RS16265
uniprot id: D9R8P4
names: Similarity
messages: Belongs to the asp23 family.

610130:CLOSA RS06615
gene id: 610130:CLOSA_RS06615
uniprot id: D9R8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

610130:CLOSA RS08720
gene id: 610130:CLOSA_RS08720
uniprot id: D9QZ67
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

610130:CLOSA RS10690
gene id: 610130:CLOSA_RS10690
uniprot id: D9R247
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

610130:CLOSA RS16840
gene id: 610130:CLOSA_RS16840
uniprot id: D9R9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS18995
gene id: 610130:CLOSA_RS18995
uniprot id: D9QZR9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19870
gene id: 610130:CLOSA_RS19870
uniprot id: D9R1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

610130:CLOSA RS06735
gene id: 610130:CLOSA_RS06735
uniprot id: D9R8U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

610130:CLOSA RS13075
gene id: 610130:CLOSA_RS13075
uniprot id: D9R554
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS09170
gene id: 610130:CLOSA_RS09170
uniprot id: D9QZE6
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS21070
gene id: 610130:CLOSA_RS21070
uniprot id: D9R3I0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

610130:CLOSA RS01980
gene id: 610130:CLOSA_RS01980
uniprot id: D9R324
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS04070
gene id: 610130:CLOSA_RS04070
uniprot id: D9R5X8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

610130:CLOSA RS19570
gene id: 610130:CLOSA_RS19570
uniprot id: D9R0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS04850
gene id: 610130:CLOSA_RS04850
uniprot id: D9R6Q3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

610130:CLOSA RS15670
gene id: 610130:CLOSA_RS15670
uniprot id: D9R804
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

610130:CLOSA RS20160
gene id: 610130:CLOSA_RS20160
uniprot id: D9R1K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

610130:CLOSA RS08495
gene id: 610130:CLOSA_RS08495
uniprot id: D9RAJ4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

610130:CLOSA RS10150
gene id: 610130:CLOSA_RS10150
uniprot id: D9R140
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

610130:CLOSA RS18140
gene id: 610130:CLOSA_RS18140
uniprot id: D9RAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11450
gene id: 610130:CLOSA_RS11450
uniprot id: D9R397
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS02030
gene id: 610130:CLOSA_RS02030
uniprot id: D9R334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

610130:CLOSA RS17350
gene id: 610130:CLOSA_RS17350
uniprot id: D9RA03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

610130:CLOSA RS15955
gene id: 610130:CLOSA_RS15955
uniprot id: D9R8I7
names: Subcellular Location Annotation
messages: Cell membrane

610130:CLOSA RS16925
gene id: 610130:CLOSA_RS16925
uniprot id: D9R9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

610130:CLOSA RS21100
gene id: 610130:CLOSA_RS21100
uniprot id: D9R3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10005
gene id: 610130:CLOSA_RS10005
uniprot id: D9R110
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

610130:CLOSA RS09360
gene id: 610130:CLOSA_RS09360
uniprot id: D9QZY5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

610130:CLOSA RS16055
gene id: 610130:CLOSA_RS16055
uniprot id: D9R8K3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

610130:CLOSA RS19340
gene id: 610130:CLOSA_RS19340
uniprot id: D9R0D2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

610130:CLOSA RS01850
gene id: 610130:CLOSA_RS01850
uniprot id: D9R301
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

610130:CLOSA RS14515
gene id: 610130:CLOSA_RS14515
uniprot id: D9R701
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

610130:CLOSA RS15885
gene id: 610130:CLOSA_RS15885
uniprot id: D9R8H2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

610130:CLOSA RS18850
gene id: 610130:CLOSA_RS18850
uniprot id: D9QZP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS18025
gene id: 610130:CLOSA_RS18025
uniprot id: D9RAQ9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

610130:CLOSA RS14900
gene id: 610130:CLOSA_RS14900
uniprot id: D9R776
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02905
gene id: 610130:CLOSA_RS02905
uniprot id: D9R4L1
names: Similarity
messages: Belongs to the pirin family.

610130:CLOSA RS05100
gene id: 610130:CLOSA_RS05100
uniprot id: D9R6V1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

610130:CLOSA RS01250
gene id: 610130:CLOSA_RS01250
uniprot id: D9R1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

610130:CLOSA RS18785
gene id: 610130:CLOSA_RS18785
uniprot id: D9QZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

610130:CLOSA RS02685
gene id: 610130:CLOSA_RS02685
uniprot id: D9R442
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

610130:CLOSA RS09135
gene id: 610130:CLOSA_RS09135
uniprot id: D9QZD9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS06090
gene id: 610130:CLOSA_RS06090
uniprot id: D9R848
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

610130:CLOSA RS15600
gene id: 610130:CLOSA_RS15600
uniprot id: D9R7Y8
names: Similarity
messages: Belongs to the GSP E family.

610130:CLOSA RS16920
gene id: 610130:CLOSA_RS16920
uniprot id: D9R9E8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09030
gene id: 610130:CLOSA_RS09030
uniprot id: D9QZB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09715
gene id: 610130:CLOSA_RS09715
uniprot id: D9R048
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

610130:CLOSA RS15870
gene id: 610130:CLOSA_RS15870
uniprot id: D9R8G9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS16050
gene id: 610130:CLOSA_RS16050
uniprot id: D9R8K2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

610130:CLOSA RS04565
gene id: 610130:CLOSA_RS04565
uniprot id: D9R668
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

610130:CLOSA RS04790
gene id: 610130:CLOSA_RS04790
uniprot id: D9R6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS16215
gene id: 610130:CLOSA_RS16215
uniprot id: D9R8N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS11140
gene id: 610130:CLOSA_RS11140
uniprot id: D9R2D4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS00355
gene id: 610130:CLOSA_RS00355
uniprot id: D9R0Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06630
gene id: 610130:CLOSA_RS06630
uniprot id: D9R8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

610130:CLOSA RS22690
gene id: 610130:CLOSA_RS22690
uniprot id: D9R5N2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS16345
gene id: 610130:CLOSA_RS16345
uniprot id: D9R8R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

610130:CLOSA RS06900
gene id: 610130:CLOSA_RS06900
uniprot id: D9R8X9
names: Similarity
messages: Belongs to the asparagine synthetase family.

610130:CLOSA RS13775
gene id: 610130:CLOSA_RS13775
uniprot id: D9R5V5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS09730
gene id: 610130:CLOSA_RS09730
uniprot id: D9R051
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

610130:CLOSA RS00645
gene id: 610130:CLOSA_RS00645
uniprot id: D9R0W3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS01415
gene id: 610130:CLOSA_RS01415
uniprot id: D9R215
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

610130:CLOSA RS09355
gene id: 610130:CLOSA_RS09355
uniprot id: D9QZY4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

610130:CLOSA RS19715
gene id: 610130:CLOSA_RS19715
uniprot id: D9R0K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS04825
gene id: 610130:CLOSA_RS04825
uniprot id: D9R6P8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

610130:CLOSA RS06530
gene id: 610130:CLOSA_RS06530
uniprot id: D9R8D3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS17390
gene id: 610130:CLOSA_RS17390
uniprot id: D9RA11
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

610130:CLOSA RS04700
gene id: 610130:CLOSA_RS04700
uniprot id: D9R6M3
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10815
gene id: 610130:CLOSA_RS10815
uniprot id: D9R272
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20165
gene id: 610130:CLOSA_RS20165
uniprot id: D9R1K6
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-822 that is involved in catalysis.

610130:CLOSA RS18920
gene id: 610130:CLOSA_RS18920
uniprot id: D9QZQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

610130:CLOSA RS08480
gene id: 610130:CLOSA_RS08480
uniprot id: D9RAJ1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

610130:CLOSA RS08265
gene id: 610130:CLOSA_RS08265
uniprot id: D9RAE9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

610130:CLOSA RS14740
gene id: 610130:CLOSA_RS14740
uniprot id: D9R744
names: Similarity
messages: Belongs to the EamA transporter family.

610130:CLOSA RS19865
gene id: 610130:CLOSA_RS19865
uniprot id: D9R1E7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

610130:CLOSA RS21325
gene id: 610130:CLOSA_RS21325
uniprot id: D9R3N0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

610130:CLOSA RS16520
gene id: 610130:CLOSA_RS16520
uniprot id: D9R973
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

610130:CLOSA RS02380
gene id: 610130:CLOSA_RS02380
uniprot id: D9R3Y2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

610130:CLOSA RS17935
gene id: 610130:CLOSA_RS17935
uniprot id: D9RAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS20100
gene id: 610130:CLOSA_RS20100
uniprot id: D9R1J3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS17330
gene id: 610130:CLOSA_RS17330
uniprot id: D9R9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

610130:CLOSA RS13330
gene id: 610130:CLOSA_RS13330
uniprot id: D9R5M8
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

610130:CLOSA RS01795
gene id: 610130:CLOSA_RS01795
uniprot id: D9R2Z0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS11515
gene id: 610130:CLOSA_RS11515
uniprot id: D9R3B0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS20075
gene id: 610130:CLOSA_RS20075
uniprot id: D9R1I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

610130:CLOSA RS02680
gene id: 610130:CLOSA_RS02680
uniprot id: D9R441
names: Similarity
messages: Belongs to the P(II) protein family.

610130:CLOSA RS11870
gene id: 610130:CLOSA_RS11870
uniprot id: D9R454
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

610130:CLOSA RS12650
gene id: 610130:CLOSA_RS12650
uniprot id: D9R4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

610130:CLOSA RS19135
gene id: 610130:CLOSA_RS19135
uniprot id: D9R090
names: Similarity
messages: Belongs to the ABC transporter superfamily.

610130:CLOSA RS06080
gene id: 610130:CLOSA_RS06080
uniprot id: D9R846
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS01695
gene id: 610130:CLOSA_RS01695
uniprot id: D9R2X0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

610130:CLOSA RS16735
gene id: 610130:CLOSA_RS16735
uniprot id: D9R9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS03230
gene id: 610130:CLOSA_RS03230
uniprot id: D9R4S3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

610130:CLOSA RS09755
gene id: 610130:CLOSA_RS09755
uniprot id: D9R056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS03765
gene id: 610130:CLOSA_RS03765
uniprot id: D9R5D9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS15125
gene id: 610130:CLOSA_RS15125
uniprot id: D9R7C0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02305
gene id: 610130:CLOSA_RS02305
uniprot id: D9R3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

610130:CLOSA RS18310
gene id: 610130:CLOSA_RS18310
uniprot id: D9RAW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

610130:CLOSA RS12080
gene id: 610130:CLOSA_RS12080
uniprot id: D9R496
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS14850
gene id: 610130:CLOSA_RS14850
uniprot id: D9R766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05095
gene id: 610130:CLOSA_RS05095
uniprot id: D9R6V0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

610130:CLOSA RS14800
gene id: 610130:CLOSA_RS14800
uniprot id: D9R756
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

610130:CLOSA RS00780
gene id: 610130:CLOSA_RS00780
uniprot id: D9R0Z0
names: Similarity
messages: Belongs to the Fur family.

610130:CLOSA RS18770
gene id: 610130:CLOSA_RS18770
uniprot id: D9QZM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

610130:CLOSA RS00010
gene id: 610130:CLOSA_RS00010
uniprot id: D9QZU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

610130:CLOSA RS05820
gene id: 610130:CLOSA_RS05820
uniprot id: D9R7M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

610130:CLOSA RS10605
gene id: 610130:CLOSA_RS10605
uniprot id: D9R230
names: Similarity
messages: Belongs to the UPF0102 family.

610130:CLOSA RS02335
gene id: 610130:CLOSA_RS02335
uniprot id: D9R3X3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

610130:CLOSA RS04595
gene id: 610130:CLOSA_RS04595
uniprot id: D9R674
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

610130:CLOSA RS04630
gene id: 610130:CLOSA_RS04630
uniprot id: D9R681
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

610130:CLOSA RS00855
gene id: 610130:CLOSA_RS00855
uniprot id: D9R1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

610130:CLOSA RS15930
gene id: 610130:CLOSA_RS15930
uniprot id: D9R8I2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

610130:CLOSA RS17450
gene id: 610130:CLOSA_RS17450
uniprot id: D9RA22
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

610130:CLOSA RS10125
gene id: 610130:CLOSA_RS10125
uniprot id: D9R135
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS03065
gene id: 610130:CLOSA_RS03065
uniprot id: D9R4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

610130:CLOSA RS04145
gene id: 610130:CLOSA_RS04145
uniprot id: D9R5Y9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

610130:CLOSA RS03495
gene id: 610130:CLOSA_RS03495
uniprot id: D9R589
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

610130:CLOSA RS03060
gene id: 610130:CLOSA_RS03060
uniprot id: D9R4P0
names: Similarity
messages: Belongs to the peptidase A8 family.

610130:CLOSA RS20060
gene id: 610130:CLOSA_RS20060
uniprot id: D9R1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

610130:CLOSA RS21535
gene id: 610130:CLOSA_RS21535
uniprot id: D9R3S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS10405
gene id: 610130:CLOSA_RS10405
uniprot id: D9R192
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

610130:CLOSA RS17545
gene id: 610130:CLOSA_RS17545
uniprot id: D9RA41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS17345
gene id: 610130:CLOSA_RS17345
uniprot id: D9RA02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

610130:CLOSA RS06240
gene id: 610130:CLOSA_RS06240
uniprot id: D9R878
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS08000
gene id: 610130:CLOSA_RS08000
uniprot id: D9RA97
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

610130:CLOSA RS18725
gene id: 610130:CLOSA_RS18725
uniprot id: D9QZL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

610130:CLOSA RS00240
gene id: 610130:CLOSA_RS00240
uniprot id: D9R0N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

610130:CLOSA RS10480
gene id: 610130:CLOSA_RS10480
uniprot id: D9R1A8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

610130:CLOSA RS12730
gene id: 610130:CLOSA_RS12730
uniprot id: D9R4Y7
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

610130:CLOSA RS05575
gene id: 610130:CLOSA_RS05575
uniprot id: D9R7H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

610130:CLOSA RS12595
gene id: 610130:CLOSA_RS12595
uniprot id: D9R4W0
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

610130:CLOSA RS08565
gene id: 610130:CLOSA_RS08565
uniprot id: D9RAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

610130:CLOSA RS01910
gene id: 610130:CLOSA_RS01910
uniprot id: D9R313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS07405
gene id: 610130:CLOSA_RS07405
uniprot id: D9R9K8
names: Similarity
messages: Belongs to the FGGY kinase family.

610130:CLOSA RS08560
gene id: 610130:CLOSA_RS08560
uniprot id: D9RAK8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

610130:CLOSA RS15435
gene id: 610130:CLOSA_RS15435
uniprot id: D9R7V8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

610130:CLOSA RS09590
gene id: 610130:CLOSA_RS09590
uniprot id: D9R025
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

610130:CLOSA RS02520
gene id: 610130:CLOSA_RS02520
uniprot id: D9R410
names: Similarity
messages: Belongs to the BMP lipoprotein family.

610130:CLOSA RS03010
gene id: 610130:CLOSA_RS03010
uniprot id: D9R4N0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

610130:CLOSA RS16720
gene id: 610130:CLOSA_RS16720
uniprot id: D9R9B2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS06000
gene id: 610130:CLOSA_RS06000
uniprot id: D9R7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11640
gene id: 610130:CLOSA_RS11640
uniprot id: D9R3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

610130:CLOSA RS16075
gene id: 610130:CLOSA_RS16075
uniprot id: D9R8K7
names: Similarity
messages: Belongs to the CapA family.

610130:CLOSA RS13045
gene id: 610130:CLOSA_RS13045
uniprot id: D9R548
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

610130:CLOSA RS14095
gene id: 610130:CLOSA_RS14095
uniprot id: D9R6E3
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS02630
gene id: 610130:CLOSA_RS02630
uniprot id: D9R432
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02135
gene id: 610130:CLOSA_RS02135
uniprot id: D9R3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

610130:CLOSA RS12295
gene id: 610130:CLOSA_RS12295
uniprot id: D9R4D6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

610130:CLOSA RS20435
gene id: 610130:CLOSA_RS20435
uniprot id: D9R2F3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

610130:CLOSA RS09905
gene id: 610130:CLOSA_RS09905
uniprot id: D9R086
names: Similarity
messages: Belongs to the asp23 family.

610130:CLOSA RS04860
gene id: 610130:CLOSA_RS04860
uniprot id: D9R6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

610130:CLOSA RS02245
gene id: 610130:CLOSA_RS02245
uniprot id: D9R3V6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

610130:CLOSA RS10940
gene id: 610130:CLOSA_RS10940
uniprot id: D9R298
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS03875
gene id: 610130:CLOSA_RS03875
uniprot id: D9R5G2
names: Similarity
messages: Belongs to the peptidase S14 family.

610130:CLOSA RS00055
gene id: 610130:CLOSA_RS00055
uniprot id: D9QZV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

610130:CLOSA RS13100
gene id: 610130:CLOSA_RS13100
uniprot id: D9R559
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS17835
gene id: 610130:CLOSA_RS17835
uniprot id: D9RAM2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

610130:CLOSA RS12045
gene id: 610130:CLOSA_RS12045
uniprot id: D9R488
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09750
gene id: 610130:CLOSA_RS09750
uniprot id: D9R055
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS12240
gene id: 610130:CLOSA_RS12240
uniprot id: D9R4C6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS16460
gene id: 610130:CLOSA_RS16460
uniprot id: D9R961
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

610130:CLOSA RS18255
gene id: 610130:CLOSA_RS18255
uniprot id: D9RAV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

610130:CLOSA RS14675
gene id: 610130:CLOSA_RS14675
uniprot id: D9R731
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

610130:CLOSA RS09705
gene id: 610130:CLOSA_RS09705
uniprot id: D9R046
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

610130:CLOSA RS07700
gene id: 610130:CLOSA_RS07700
uniprot id: D9R9R8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS02440
gene id: 610130:CLOSA_RS02440
uniprot id: D9R3Z4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

610130:CLOSA RS21125
gene id: 610130:CLOSA_RS21125
uniprot id: D9R3J1
names: Similarity
messages: Belongs to the glycosyl hydrolase.

610130:CLOSA RS02225
gene id: 610130:CLOSA_RS02225
uniprot id: D9R3V2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS19375
gene id: 610130:CLOSA_RS19375
uniprot id: D9R0D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05585
gene id: 610130:CLOSA_RS05585
uniprot id: D9R7H4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

610130:CLOSA RS02095
gene id: 610130:CLOSA_RS02095
uniprot id: D9R347
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

610130:CLOSA RS19610
gene id: 610130:CLOSA_RS19610
uniprot id: D9R0I6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS05175
gene id: 610130:CLOSA_RS05175
uniprot id: D9R6W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

610130:CLOSA RS21435
gene id: 610130:CLOSA_RS21435
uniprot id: D9R3Q1
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS19000
gene id: 610130:CLOSA_RS19000
uniprot id: D9QZS0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

610130:CLOSA RS00300
gene id: 610130:CLOSA_RS00300
uniprot id: D9R0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06190
gene id: 610130:CLOSA_RS06190
uniprot id: D9R868
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS09560
gene id: 610130:CLOSA_RS09560
uniprot id: D9R019
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

610130:CLOSA RS07420
gene id: 610130:CLOSA_RS07420
uniprot id: D9R9L1
names: Similarity
messages: Belongs to the BtpA family.

610130:CLOSA RS12805
gene id: 610130:CLOSA_RS12805
uniprot id: D9R502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS03515
gene id: 610130:CLOSA_RS03515
uniprot id: D9R593
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

610130:CLOSA RS03655
gene id: 610130:CLOSA_RS03655
uniprot id: D9R5B9
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS11355
gene id: 610130:CLOSA_RS11355
uniprot id: D9R380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS13250
gene id: 610130:CLOSA_RS13250
uniprot id: D9R5L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

610130:CLOSA RS19170
gene id: 610130:CLOSA_RS19170
uniprot id: D9R098
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

610130:CLOSA RS13580
gene id: 610130:CLOSA_RS13580
uniprot id: D9R5S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: Homotrimer.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

610130:CLOSA RS00875
gene id: 610130:CLOSA_RS00875
uniprot id: D9R1R6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

610130:CLOSA RS04510
gene id: 610130:CLOSA_RS04510
uniprot id: D9R657
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

610130:CLOSA RS01535
gene id: 610130:CLOSA_RS01535
uniprot id: D9R2U0
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS03115
gene id: 610130:CLOSA_RS03115
uniprot id: D9R4Q1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

610130:CLOSA RS15425
gene id: 610130:CLOSA_RS15425
uniprot id: D9R7V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

610130:CLOSA RS16235
gene id: 610130:CLOSA_RS16235
uniprot id: D9R8N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

610130:CLOSA RS18300
gene id: 610130:CLOSA_RS18300
uniprot id: D9RAW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

610130:CLOSA RS11125
gene id: 610130:CLOSA_RS11125
uniprot id: D9R2D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

610130:CLOSA RS20625
gene id: 610130:CLOSA_RS20625
uniprot id: D9R2J0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

610130:CLOSA RS02445
gene id: 610130:CLOSA_RS02445
uniprot id: D9R3Z5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS05265
gene id: 610130:CLOSA_RS05265
uniprot id: D9R6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS17025
gene id: 610130:CLOSA_RS17025
uniprot id: D9R9G9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

610130:CLOSA RS05200
gene id: 610130:CLOSA_RS05200
uniprot id: D9R6X0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

610130:CLOSA RS09285
gene id: 610130:CLOSA_RS09285
uniprot id: D9QZX0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10850
gene id: 610130:CLOSA_RS10850
uniprot id: D9R279
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS08520
gene id: 610130:CLOSA_RS08520
uniprot id: D9RAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

610130:CLOSA RS10980
gene id: 610130:CLOSA_RS10980
uniprot id: D9R2A3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

610130:CLOSA RS08220
gene id: 610130:CLOSA_RS08220
uniprot id: D9RAE0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

610130:CLOSA RS17395
gene id: 610130:CLOSA_RS17395
uniprot id: D9RA12
names: Similarity
messages: Belongs to the MotB family.

610130:CLOSA RS11930
gene id: 610130:CLOSA_RS11930
uniprot id: D9R466
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

610130:CLOSA RS17875
gene id: 610130:CLOSA_RS17875
uniprot id: D9RAN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

610130:CLOSA RS09940
gene id: 610130:CLOSA_RS09940
uniprot id: D9R0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

610130:CLOSA RS01900
gene id: 610130:CLOSA_RS01900
uniprot id: D9R311
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

610130:CLOSA RS00920
gene id: 610130:CLOSA_RS00920
uniprot id: D9R1S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS19380
gene id: 610130:CLOSA_RS19380
uniprot id: D9R0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS21285
gene id: 610130:CLOSA_RS21285
uniprot id: D9R3M3
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

610130:CLOSA RS17455
gene id: 610130:CLOSA_RS17455
uniprot id: D9RA23
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

610130:CLOSA RS16625
gene id: 610130:CLOSA_RS16625
uniprot id: D9R993
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS10310
gene id: 610130:CLOSA_RS10310
uniprot id: D9R172
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

610130:CLOSA RS20780
gene id: 610130:CLOSA_RS20780
uniprot id: D9R2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

610130:CLOSA RS20400
gene id: 610130:CLOSA_RS20400
uniprot id: D9R1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

610130:CLOSA RS18890
gene id: 610130:CLOSA_RS18890
uniprot id: D9QZP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

610130:CLOSA RS08430
gene id: 610130:CLOSA_RS08430
uniprot id: D9RAI1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

610130:CLOSA RS18780
gene id: 610130:CLOSA_RS18780
uniprot id: D9QZM6
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10135
gene id: 610130:CLOSA_RS10135
uniprot id: D9R137
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

610130:CLOSA RS00490
gene id: 610130:CLOSA_RS00490
uniprot id: D9R0T2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS10640
gene id: 610130:CLOSA_RS10640
uniprot id: D9R237
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

610130:CLOSA RS21965
gene id: 610130:CLOSA_RS21965
uniprot id: D9R0G0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20055
gene id: 610130:CLOSA_RS20055
uniprot id: D9R1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

610130:CLOSA RS02400
gene id: 610130:CLOSA_RS02400
uniprot id: D9R3Y6
names: Similarity
messages: Belongs to the SfsA family.

610130:CLOSA RS05135
gene id: 610130:CLOSA_RS05135
uniprot id: D9R6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15350
gene id: 610130:CLOSA_RS15350
uniprot id: D9R7U3
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

610130:CLOSA RS19905
gene id: 610130:CLOSA_RS19905
uniprot id: D9R1F5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

610130:CLOSA RS20190
gene id: 610130:CLOSA_RS20190
uniprot id: D9R1L1
names: Similarity
messages: Belongs to the EamA transporter family.

610130:CLOSA RS20875
gene id: 610130:CLOSA_RS20875
uniprot id: D9R2N9
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS12150
gene id: 610130:CLOSA_RS12150
uniprot id: D9R4B0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS03220
gene id: 610130:CLOSA_RS03220
uniprot id: D9R4S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

610130:CLOSA RS04805
gene id: 610130:CLOSA_RS04805
uniprot id: D9R6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

610130:CLOSA RS12450
gene id: 610130:CLOSA_RS12450
uniprot id: D9R4G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

610130:CLOSA RS05660
gene id: 610130:CLOSA_RS05660
uniprot id: D9R7I9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

610130:CLOSA RS11385
gene id: 610130:CLOSA_RS11385
uniprot id: D9R385
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS04950
gene id: 610130:CLOSA_RS04950
uniprot id: D9R6S2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

610130:CLOSA RS07690
gene id: 610130:CLOSA_RS07690
uniprot id: D9R9R6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS01805
gene id: 610130:CLOSA_RS01805
uniprot id: D9R2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

610130:CLOSA RS11750
gene id: 610130:CLOSA_RS11750
uniprot id: D9R3F1
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

610130:CLOSA RS17270
gene id: 610130:CLOSA_RS17270
uniprot id: D9R9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

610130:CLOSA RS05285
gene id: 610130:CLOSA_RS05285
uniprot id: D9R6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

610130:CLOSA RS00360
gene id: 610130:CLOSA_RS00360
uniprot id: D9R0Q6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

610130:CLOSA RS18935
gene id: 610130:CLOSA_RS18935
uniprot id: D9QZQ7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

610130:CLOSA RS00180
gene id: 610130:CLOSA_RS00180
uniprot id: D9R0L9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS09570
gene id: 610130:CLOSA_RS09570
uniprot id: D9R021
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS04120
gene id: 610130:CLOSA_RS04120
uniprot id: D9R5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

610130:CLOSA RS13280
gene id: 610130:CLOSA_RS13280
uniprot id: D9R5L9
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

610130:CLOSA RS01620
gene id: 610130:CLOSA_RS01620
uniprot id: D9R2V7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

610130:CLOSA RS04285
gene id: 610130:CLOSA_RS04285
uniprot id: D9R615
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

610130:CLOSA RS08750
gene id: 610130:CLOSA_RS08750
uniprot id: D9QZ74
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

610130:CLOSA RS05580
gene id: 610130:CLOSA_RS05580
uniprot id: D9R7H3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

610130:CLOSA RS05360
gene id: 610130:CLOSA_RS05360
uniprot id: D9R7C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

610130:CLOSA RS15325
gene id: 610130:CLOSA_RS15325
uniprot id: D9R7T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS07660
gene id: 610130:CLOSA_RS07660
uniprot id: D9R9Q9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

610130:CLOSA RS17070
gene id: 610130:CLOSA_RS17070
uniprot id: D9R9I0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

610130:CLOSA RS17540
gene id: 610130:CLOSA_RS17540
uniprot id: D9RA40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

610130:CLOSA RS15195
gene id: 610130:CLOSA_RS15195
uniprot id: D9R7R2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

610130:CLOSA RS19030
gene id: 610130:CLOSA_RS19030
uniprot id: D9QZS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

610130:CLOSA RS09380
gene id: 610130:CLOSA_RS09380
uniprot id: D9QZY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

610130:CLOSA RS09605
gene id: 610130:CLOSA_RS09605
uniprot id: D9R027
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

610130:CLOSA RS06170
gene id: 610130:CLOSA_RS06170
uniprot id: D9R864
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

610130:CLOSA RS20980
gene id: 610130:CLOSA_RS20980
uniprot id: D9R2R0
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS18030
gene id: 610130:CLOSA_RS18030
uniprot id: D9RAR0
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

610130:CLOSA RS15160
gene id: 610130:CLOSA_RS15160
uniprot id: D9R7Q5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS09735
gene id: 610130:CLOSA_RS09735
uniprot id: D9R052
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS11235
gene id: 610130:CLOSA_RS11235
uniprot id: D9R356
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

610130:CLOSA RS12285
gene id: 610130:CLOSA_RS12285
uniprot id: D9R4D5
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS13655
gene id: 610130:CLOSA_RS13655
uniprot id: D9R5U1
names: Similarity
messages: Belongs to the UPF0251 family.

610130:CLOSA RS15445
gene id: 610130:CLOSA_RS15445
uniprot id: D9R7W0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

610130:CLOSA RS04100
gene id: 610130:CLOSA_RS04100
uniprot id: D9R5Y1
names: Similarity
messages: Belongs to the CvfB family.

610130:CLOSA RS01475
gene id: 610130:CLOSA_RS01475
uniprot id: D9R2S8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS16240
gene id: 610130:CLOSA_RS16240
uniprot id: D9R8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

610130:CLOSA RS02320
gene id: 610130:CLOSA_RS02320
uniprot id: D9R3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11065
gene id: 610130:CLOSA_RS11065
uniprot id: D9R2B9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

610130:CLOSA RS18395
gene id: 610130:CLOSA_RS18395
uniprot id: D9RAX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS17710
gene id: 610130:CLOSA_RS17710
uniprot id: D9RA73
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS00350
gene id: 610130:CLOSA_RS00350
uniprot id: D9R0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15995
gene id: 610130:CLOSA_RS15995
uniprot id: D9R8J5
names: Similarity
messages: Belongs to the UPF0145 family.

610130:CLOSA RS03050
gene id: 610130:CLOSA_RS03050
uniprot id: D9R4N8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

610130:CLOSA RS03470
gene id: 610130:CLOSA_RS03470
uniprot id: D9R585
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

610130:CLOSA RS20975
gene id: 610130:CLOSA_RS20975
uniprot id: D9R2Q9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07550
gene id: 610130:CLOSA_RS07550
uniprot id: D9R9N7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

610130:CLOSA RS08240
gene id: 610130:CLOSA_RS08240
uniprot id: D9RAE4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

610130:CLOSA RS17290
gene id: 610130:CLOSA_RS17290
uniprot id: D9R9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

610130:CLOSA RS15130
gene id: 610130:CLOSA_RS15130
uniprot id: D9R7C1
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS20720
gene id: 610130:CLOSA_RS20720
uniprot id: D9R2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

610130:CLOSA RS01610
gene id: 610130:CLOSA_RS01610
uniprot id: D9R2V4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS09385
gene id: 610130:CLOSA_RS09385
uniprot id: D9QZZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS00020
gene id: 610130:CLOSA_RS00020
uniprot id: D9QZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

610130:CLOSA RS16930
gene id: 610130:CLOSA_RS16930
uniprot id: D9R9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

610130:CLOSA RS11130
gene id: 610130:CLOSA_RS11130
uniprot id: D9R2D2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

610130:CLOSA RS11315
gene id: 610130:CLOSA_RS11315
uniprot id: D9R372
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

610130:CLOSA RS09725
gene id: 610130:CLOSA_RS09725
uniprot id: D9R050
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

610130:CLOSA RS20970
gene id: 610130:CLOSA_RS20970
uniprot id: D9R2Q8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07375
gene id: 610130:CLOSA_RS07375
uniprot id: D9R9K2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

610130:CLOSA RS20995
gene id: 610130:CLOSA_RS20995
uniprot id: D9R2R3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS01870
gene id: 610130:CLOSA_RS01870
uniprot id: D9R305
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

610130:CLOSA RS11050
gene id: 610130:CLOSA_RS11050
uniprot id: D9R2B6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

610130:CLOSA RS12270
gene id: 610130:CLOSA_RS12270
uniprot id: D9R4D2
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS05940
gene id: 610130:CLOSA_RS05940
uniprot id: D9R7P1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS21215
gene id: 610130:CLOSA_RS21215
uniprot id: D9R3K9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07240
gene id: 610130:CLOSA_RS07240
uniprot id: D9R951
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS11555
gene id: 610130:CLOSA_RS11555
uniprot id: D9R3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

610130:CLOSA RS02275
gene id: 610130:CLOSA_RS02275
uniprot id: D9R3W1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS08605
gene id: 610130:CLOSA_RS08605
uniprot id: D9QZ44
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

610130:CLOSA RS07395
gene id: 610130:CLOSA_RS07395
uniprot id: D9R9K6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS07565
gene id: 610130:CLOSA_RS07565
uniprot id: D9R9P0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

610130:CLOSA RS11240
gene id: 610130:CLOSA_RS11240
uniprot id: D9R357
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

610130:CLOSA RS02735
gene id: 610130:CLOSA_RS02735
uniprot id: D9R452
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

610130:CLOSA RS06175
gene id: 610130:CLOSA_RS06175
uniprot id: D9R865
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS21865
gene id: 610130:CLOSA_RS21865
uniprot id: D9R8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS21045
gene id: 610130:CLOSA_RS21045
uniprot id: D9R3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

610130:CLOSA RS17315
gene id: 610130:CLOSA_RS17315
uniprot id: D9R9Z6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS00420
gene id: 610130:CLOSA_RS00420
uniprot id: D9R0R7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

610130:CLOSA RS09995
gene id: 610130:CLOSA_RS09995
uniprot id: D9R108
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

610130:CLOSA RS02150
gene id: 610130:CLOSA_RS02150
uniprot id: D9R3T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

610130:CLOSA RS08035
gene id: 610130:CLOSA_RS08035
uniprot id: D9RAA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

610130:CLOSA RS09580
gene id: 610130:CLOSA_RS09580
uniprot id: D9R023
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

610130:CLOSA RS21140
gene id: 610130:CLOSA_RS21140
uniprot id: D9R3J4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

610130:CLOSA RS11285
gene id: 610130:CLOSA_RS11285
uniprot id: D9R366
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

610130:CLOSA RS06915
gene id: 610130:CLOSA_RS06915
uniprot id: D9R8Y2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

610130:CLOSA RS19700
gene id: 610130:CLOSA_RS19700
uniprot id: D9R0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05470
gene id: 610130:CLOSA_RS05470
uniprot id: D9R7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS14695
gene id: 610130:CLOSA_RS14695
uniprot id: D9R735
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS08055
gene id: 610130:CLOSA_RS08055
uniprot id: D9RAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

610130:CLOSA RS08185
gene id: 610130:CLOSA_RS08185
uniprot id: D9RAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02355
gene id: 610130:CLOSA_RS02355
uniprot id: D9R3X7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS18270
gene id: 610130:CLOSA_RS18270
uniprot id: D9RAV5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

610130:CLOSA RS11215
gene id: 610130:CLOSA_RS11215
uniprot id: D9R352
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS12490
gene id: 610130:CLOSA_RS12490
uniprot id: D9R4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

610130:CLOSA RS05705
gene id: 610130:CLOSA_RS05705
uniprot id: D9R7J8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS18945
gene id: 610130:CLOSA_RS18945
uniprot id: D9QZQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

610130:CLOSA RS00495
gene id: 610130:CLOSA_RS00495
uniprot id: D9R0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS01945
gene id: 610130:CLOSA_RS01945
uniprot id: D9R317
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

610130:CLOSA RS05630
gene id: 610130:CLOSA_RS05630
uniprot id: D9R7I3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

610130:CLOSA RS12105
gene id: 610130:CLOSA_RS12105
uniprot id: D9R4A1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS18280
gene id: 610130:CLOSA_RS18280
uniprot id: D9RAV7
names: Similarity
messages: Belongs to the ThiD family.

610130:CLOSA RS19490
gene id: 610130:CLOSA_RS19490
uniprot id: D9R0G3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

610130:CLOSA RS17320
gene id: 610130:CLOSA_RS17320
uniprot id: D9R9Z7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

610130:CLOSA RS10335
gene id: 610130:CLOSA_RS10335
uniprot id: D9R177
names: Similarity
messages: Belongs to the UPF0758 family.

610130:CLOSA RS15015
gene id: 610130:CLOSA_RS15015
uniprot id: D9R799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11840
gene id: 610130:CLOSA_RS11840
uniprot id: D9R3G9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS16090
gene id: 610130:CLOSA_RS16090
uniprot id: D9R8L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11090
gene id: 610130:CLOSA_RS11090
uniprot id: D9R2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

610130:CLOSA RS06535
gene id: 610130:CLOSA_RS06535
uniprot id: D9R8D4
names: Similarity
messages: Belongs to the manganese catalase family.

610130:CLOSA RS11070
gene id: 610130:CLOSA_RS11070
uniprot id: D9R2C0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

610130:CLOSA RS09775
gene id: 610130:CLOSA_RS09775
uniprot id: D9R060
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS05140
gene id: 610130:CLOSA_RS05140
uniprot id: D9R6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS20065
gene id: 610130:CLOSA_RS20065
uniprot id: D9R1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

610130:CLOSA RS16365
gene id: 610130:CLOSA_RS16365
uniprot id: D9R8R4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS00605
gene id: 610130:CLOSA_RS00605
uniprot id: D9R0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

610130:CLOSA RS18925
gene id: 610130:CLOSA_RS18925
uniprot id: D9QZQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

610130:CLOSA RS11865
gene id: 610130:CLOSA_RS11865
uniprot id: D9R3H4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

610130:CLOSA RS20090
gene id: 610130:CLOSA_RS20090
uniprot id: D9R1J1
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS21550
gene id: 610130:CLOSA_RS21550
uniprot id: D9R3S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

610130:CLOSA RS15420
gene id: 610130:CLOSA_RS15420
uniprot id: D9R7V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS12310
gene id: 610130:CLOSA_RS12310
uniprot id: D9R4D9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

610130:CLOSA RS08140
gene id: 610130:CLOSA_RS08140
uniprot id: D9RAC5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS09050
gene id: 610130:CLOSA_RS09050
uniprot id: D9QZC2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

610130:CLOSA RS03000
gene id: 610130:CLOSA_RS03000
uniprot id: D9R4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS12460
gene id: 610130:CLOSA_RS12460
uniprot id: D9R4G8
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS01645
gene id: 610130:CLOSA_RS01645
uniprot id: D9R2W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

610130:CLOSA RS16245
gene id: 610130:CLOSA_RS16245
uniprot id: D9R8P0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

610130:CLOSA RS10750
gene id: 610130:CLOSA_RS10750
uniprot id: D9R259
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

610130:CLOSA RS15055
gene id: 610130:CLOSA_RS15055
uniprot id: D9R7A6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

610130:CLOSA RS12400
gene id: 610130:CLOSA_RS12400
uniprot id: D9R4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

610130:CLOSA RS11395
gene id: 610130:CLOSA_RS11395
uniprot id: D9R387
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

610130:CLOSA RS03135
gene id: 610130:CLOSA_RS03135
uniprot id: D9R4Q5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

610130:CLOSA RS14420
gene id: 610130:CLOSA_RS14420
uniprot id: D9R6K5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

610130:CLOSA RS10400
gene id: 610130:CLOSA_RS10400
uniprot id: D9R191
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

610130:CLOSA RS17265
gene id: 610130:CLOSA_RS17265
uniprot id: D9R9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

610130:CLOSA RS07620
gene id: 610130:CLOSA_RS07620
uniprot id: D9R9Q1
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

610130:CLOSA RS15265
gene id: 610130:CLOSA_RS15265
uniprot id: D9R7S6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS21250
gene id: 610130:CLOSA_RS21250
uniprot id: D9R3L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS14340
gene id: 610130:CLOSA_RS14340
uniprot id: D9R6J0
names: Similarity
messages: Belongs to the peptidase M24B family.

610130:CLOSA RS03545
gene id: 610130:CLOSA_RS03545
uniprot id: D9R598
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

610130:CLOSA RS20175
gene id: 610130:CLOSA_RS20175
uniprot id: D9R1K8
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

610130:CLOSA RS15490
gene id: 610130:CLOSA_RS15490
uniprot id: D9R7W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10465
gene id: 610130:CLOSA_RS10465
uniprot id: D9R1A4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

610130:CLOSA RS02290
gene id: 610130:CLOSA_RS02290
uniprot id: D9R3W4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS12230
gene id: 610130:CLOSA_RS12230
uniprot id: D9R4C4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19105
gene id: 610130:CLOSA_RS19105
uniprot id: D9QZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

610130:CLOSA RS08350
gene id: 610130:CLOSA_RS08350
uniprot id: D9RAG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

610130:CLOSA RS12050
gene id: 610130:CLOSA_RS12050
uniprot id: D9R489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS08005
gene id: 610130:CLOSA_RS08005
uniprot id: D9RA98
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

610130:CLOSA RS04250
gene id: 610130:CLOSA_RS04250
uniprot id: D9R608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

610130:CLOSA RS04520
gene id: 610130:CLOSA_RS04520
uniprot id: D9R659
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

610130:CLOSA RS02845
gene id: 610130:CLOSA_RS02845
uniprot id: D9R4K1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

610130:CLOSA RS09610
gene id: 610130:CLOSA_RS09610
uniprot id: D9R028
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

610130:CLOSA RS05850
gene id: 610130:CLOSA_RS05850
uniprot id: D9R7M7
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

610130:CLOSA RS12800
gene id: 610130:CLOSA_RS12800
uniprot id: D9R501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS12620
gene id: 610130:CLOSA_RS12620
uniprot id: D9R4W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

610130:CLOSA RS16130
gene id: 610130:CLOSA_RS16130
uniprot id: D9R8L8
names: Similarity
messages: Belongs to the peptidase M18 family.

610130:CLOSA RS01105
gene id: 610130:CLOSA_RS01105
uniprot id: D9R1V3
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS16225
gene id: 610130:CLOSA_RS16225
uniprot id: D9R8N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

610130:CLOSA RS08015
gene id: 610130:CLOSA_RS08015
uniprot id: D9RAA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

610130:CLOSA RS16255
gene id: 610130:CLOSA_RS16255
uniprot id: D9R8P2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

610130:CLOSA RS00295
gene id: 610130:CLOSA_RS00295
uniprot id: D9R0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS04280
gene id: 610130:CLOSA_RS04280
uniprot id: D9R614
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

610130:CLOSA RS12135
gene id: 610130:CLOSA_RS12135
uniprot id: D9R4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS04530
gene id: 610130:CLOSA_RS04530
uniprot id: D9R661
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

610130:CLOSA RS01230
gene id: 610130:CLOSA_RS01230
uniprot id: D9R1X8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

610130:CLOSA RS09835
gene id: 610130:CLOSA_RS09835
uniprot id: D9R071
names: Similarity
messages: Belongs to the BtpA family.

610130:CLOSA RS01160
gene id: 610130:CLOSA_RS01160
uniprot id: D9R1W4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

610130:CLOSA RS20660
gene id: 610130:CLOSA_RS20660
uniprot id: D9R2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

610130:CLOSA RS05190
gene id: 610130:CLOSA_RS05190
uniprot id: D9R6W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

610130:CLOSA RS12210
gene id: 610130:CLOSA_RS12210
uniprot id: D9R4C0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10530
gene id: 610130:CLOSA_RS10530
uniprot id: D9R1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06230
gene id: 610130:CLOSA_RS06230
uniprot id: D9R876
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

610130:CLOSA RS09485
gene id: 610130:CLOSA_RS09485
uniprot id: D9R005
names: Similarity
messages: Belongs to the EamA transporter family.

610130:CLOSA RS11785
gene id: 610130:CLOSA_RS11785
uniprot id: D9R3F8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

610130:CLOSA RS00220
gene id: 610130:CLOSA_RS00220
uniprot id: D9R0M7
names: Similarity
messages: Belongs to the fabD family.

610130:CLOSA RS06685
gene id: 610130:CLOSA_RS06685
uniprot id: D9R8T8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

610130:CLOSA RS17465
gene id: 610130:CLOSA_RS17465
uniprot id: D9RA25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

610130:CLOSA RS00930
gene id: 610130:CLOSA_RS00930
uniprot id: D9R1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

610130:CLOSA RS04725
gene id: 610130:CLOSA_RS04725
uniprot id: D9R6M8
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

610130:CLOSA RS21345
gene id: 610130:CLOSA_RS21345
uniprot id: D9R3N4
names: Similarity
messages: Belongs to the UbiD family.

610130:CLOSA RS04160
gene id: 610130:CLOSA_RS04160
uniprot id: D9R5Z2
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

610130:CLOSA RS04165
gene id: 610130:CLOSA_RS04165
uniprot id: D9R5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

610130:CLOSA RS15010
gene id: 610130:CLOSA_RS15010
uniprot id: D9R798
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

610130:CLOSA RS05545
gene id: 610130:CLOSA_RS05545
uniprot id: D9R7G6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

610130:CLOSA RS10190
gene id: 610130:CLOSA_RS10190
uniprot id: D9R148
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS16320
gene id: 610130:CLOSA_RS16320
uniprot id: D9R8Q5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

610130:CLOSA RS10625
gene id: 610130:CLOSA_RS10625
uniprot id: D9R234
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

610130:CLOSA RS11605
gene id: 610130:CLOSA_RS11605
uniprot id: D9R3C3
names: Similarity
messages: Belongs to the EamA transporter family.

610130:CLOSA RS03400
gene id: 610130:CLOSA_RS03400
uniprot id: D9R4U2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS14325
gene id: 610130:CLOSA_RS14325
uniprot id: D9R6I7
names: Similarity
messages: Belongs to the PRORSD1 family.

610130:CLOSA RS07365
gene id: 610130:CLOSA_RS07365
uniprot id: D9R9K0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

610130:CLOSA RS08360
gene id: 610130:CLOSA_RS08360
uniprot id: D9RAG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

610130:CLOSA RS15390
gene id: 610130:CLOSA_RS15390
uniprot id: D9R7U9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

610130:CLOSA RS09035
gene id: 610130:CLOSA_RS09035
uniprot id: D9QZB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15320
gene id: 610130:CLOSA_RS15320
uniprot id: D9R7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS11020
gene id: 610130:CLOSA_RS11020
uniprot id: D9R2B0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS13665
gene id: 610130:CLOSA_RS13665
uniprot id: D9R5U3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

610130:CLOSA RS16040
gene id: 610130:CLOSA_RS16040
uniprot id: D9R8K0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

610130:CLOSA RS09020
gene id: 610130:CLOSA_RS09020
uniprot id: D9QZB6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS09765
gene id: 610130:CLOSA_RS09765
uniprot id: D9R058
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

610130:CLOSA RS11135
gene id: 610130:CLOSA_RS11135
uniprot id: D9R2D3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS20465
gene id: 610130:CLOSA_RS20465
uniprot id: D9R2F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

610130:CLOSA RS15585
gene id: 610130:CLOSA_RS15585
uniprot id: D9R7Y5
names: Similarity
messages: Belongs to the peptidase A24 family.

610130:CLOSA RS02420
gene id: 610130:CLOSA_RS02420
uniprot id: D9R3Z0
names: Similarity
messages: Belongs to the glutamine synthetase family.

610130:CLOSA RS15455
gene id: 610130:CLOSA_RS15455
uniprot id: D9R7W2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

610130:CLOSA RS21055
gene id: 610130:CLOSA_RS21055
uniprot id: D9R3H7
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

610130:CLOSA RS02415
gene id: 610130:CLOSA_RS02415
uniprot id: D9R3Y9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

610130:CLOSA RS04975
gene id: 610130:CLOSA_RS04975
uniprot id: D9R6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

610130:CLOSA RS09465
gene id: 610130:CLOSA_RS09465
uniprot id: D9R001
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

610130:CLOSA RS06600
gene id: 610130:CLOSA_RS06600
uniprot id: D9R8E5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

610130:CLOSA RS08970
gene id: 610130:CLOSA_RS08970
uniprot id: D9QZA9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

610130:CLOSA RS15045
gene id: 610130:CLOSA_RS15045
uniprot id: D9R7A4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

610130:CLOSA RS08385
gene id: 610130:CLOSA_RS08385
uniprot id: D9RAH2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

610130:CLOSA RS21210
gene id: 610130:CLOSA_RS21210
uniprot id: D9R3K8
names: Similarity
messages: Belongs to the peptidase S11 family.

610130:CLOSA RS10650
gene id: 610130:CLOSA_RS10650
uniprot id: D9R239
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

610130:CLOSA RS19760
gene id: 610130:CLOSA_RS19760
uniprot id: D9R1C8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

610130:CLOSA RS13260
gene id: 610130:CLOSA_RS13260
uniprot id: D9R5L5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

610130:CLOSA RS12545
gene id: 610130:CLOSA_RS12545
uniprot id: D9R4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

610130:CLOSA RS06390
gene id: 610130:CLOSA_RS06390
uniprot id: D9R8A5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS17615
gene id: 610130:CLOSA_RS17615
uniprot id: D9RA55
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS21495
gene id: 610130:CLOSA_RS21495
uniprot id: D9R3R2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

610130:CLOSA RS10885
gene id: 610130:CLOSA_RS10885
uniprot id: D9R286
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS06745
gene id: 610130:CLOSA_RS06745
uniprot id: D9R8V0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS10270
gene id: 610130:CLOSA_RS10270
uniprot id: D9R164
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

610130:CLOSA RS18240
gene id: 610130:CLOSA_RS18240
uniprot id: D9RAU9
names: Similarity
messages: Belongs to the TrpC family.

610130:CLOSA RS02020
gene id: 610130:CLOSA_RS02020
uniprot id: D9R332
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

610130:CLOSA RS11340
gene id: 610130:CLOSA_RS11340
uniprot id: D9R377
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

610130:CLOSA RS05975
gene id: 610130:CLOSA_RS05975
uniprot id: D9R7P8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

610130:CLOSA RS11895
gene id: 610130:CLOSA_RS11895
uniprot id: D9R459
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

610130:CLOSA RS03340
gene id: 610130:CLOSA_RS03340
uniprot id: D9R4T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02545
gene id: 610130:CLOSA_RS02545
uniprot id: D9R415
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

610130:CLOSA RS16665
gene id: 610130:CLOSA_RS16665
uniprot id: D9R9A1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

610130:CLOSA RS03160
gene id: 610130:CLOSA_RS03160
uniprot id: D9R4R0
names: Similarity
messages: Belongs to the UPF0735 family.

610130:CLOSA RS07735
gene id: 610130:CLOSA_RS07735
uniprot id: D9R9S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

610130:CLOSA RS20405
gene id: 610130:CLOSA_RS20405
uniprot id: D9R1P8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

610130:CLOSA RS12530
gene id: 610130:CLOSA_RS12530
uniprot id: D9R4U7
names: Similarity
messages: Belongs to the glutamate synthase family.

610130:CLOSA RS18485
gene id: 610130:CLOSA_RS18485
uniprot id: D9QZG7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

610130:CLOSA RS00840
gene id: 610130:CLOSA_RS00840
uniprot id: D9R1Q9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS09520
gene id: 610130:CLOSA_RS09520
uniprot id: D9R011
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

610130:CLOSA RS09700
gene id: 610130:CLOSA_RS09700
uniprot id: D9R045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

610130:CLOSA RS12265
gene id: 610130:CLOSA_RS12265
uniprot id: D9R4D1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

610130:CLOSA RS04640
gene id: 610130:CLOSA_RS04640
uniprot id: D9R683
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

610130:CLOSA RS09930
gene id: 610130:CLOSA_RS09930
uniprot id: D9R0Z5
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

610130:CLOSA RS14255
gene id: 610130:CLOSA_RS14255
uniprot id: D9R6H4
names: Similarity
messages: Belongs to the peptidase A24 family.

610130:CLOSA RS10645
gene id: 610130:CLOSA_RS10645
uniprot id: D9R238
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

610130:CLOSA RS13050
gene id: 610130:CLOSA_RS13050
uniprot id: D9R549
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

610130:CLOSA RS12550
gene id: 610130:CLOSA_RS12550
uniprot id: D9R4V1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

610130:CLOSA RS04030
gene id: 610130:CLOSA_RS04030
uniprot id: D9R5X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

610130:CLOSA RS13085
gene id: 610130:CLOSA_RS13085
uniprot id: D9R556
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

610130:CLOSA RS02510
gene id: 610130:CLOSA_RS02510
uniprot id: D9R408
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

610130:CLOSA RS04815
gene id: 610130:CLOSA_RS04815
uniprot id: D9R6P6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

610130:CLOSA RS04060
gene id: 610130:CLOSA_RS04060
uniprot id: D9R5X6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS23320
gene id: 610130:CLOSA_RS23320
uniprot id: D9R0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS01100
gene id: 610130:CLOSA_RS01100
uniprot id: D9R1V2
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS02230
gene id: 610130:CLOSA_RS02230
uniprot id: D9R3V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

610130:CLOSA RS09860
gene id: 610130:CLOSA_RS09860
uniprot id: D9R076
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

610130:CLOSA RS19175
gene id: 610130:CLOSA_RS19175
uniprot id: D9R099
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

610130:CLOSA RS04310
gene id: 610130:CLOSA_RS04310
uniprot id: D9R620
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

610130:CLOSA RS18400
gene id: 610130:CLOSA_RS18400
uniprot id: D9RAY0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

610130:CLOSA RS11270
gene id: 610130:CLOSA_RS11270
uniprot id: D9R363
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02330
gene id: 610130:CLOSA_RS02330
uniprot id: D9R3X2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

610130:CLOSA RS18045
gene id: 610130:CLOSA_RS18045
uniprot id: D9RAR3
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

610130:CLOSA RS01115
gene id: 610130:CLOSA_RS01115
uniprot id: D9R1V5
names: Similarity
messages: Belongs to the UPF0309 family.

610130:CLOSA RS12760
gene id: 610130:CLOSA_RS12760
uniprot id: D9R4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS15085
gene id: 610130:CLOSA_RS15085
uniprot id: D9R7B2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

610130:CLOSA RS13230
gene id: 610130:CLOSA_RS13230
uniprot id: D9R5K9
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS07350
gene id: 610130:CLOSA_RS07350
uniprot id: D9R9J7
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

610130:CLOSA RS16250
gene id: 610130:CLOSA_RS16250
uniprot id: D9R8P1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

610130:CLOSA RS14935
gene id: 610130:CLOSA_RS14935
uniprot id: D9R783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

610130:CLOSA RS11150
gene id: 610130:CLOSA_RS11150
uniprot id: D9R2D6
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS19520
gene id: 610130:CLOSA_RS19520
uniprot id: D9R0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

610130:CLOSA RS16400
gene id: 610130:CLOSA_RS16400
uniprot id: D9R8S1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

610130:CLOSA RS13310
gene id: 610130:CLOSA_RS13310
uniprot id: D9R5M5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS16430
gene id: 610130:CLOSA_RS16430
uniprot id: D9R8S7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02425
gene id: 610130:CLOSA_RS02425
uniprot id: D9R3Z1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

610130:CLOSA RS16545
gene id: 610130:CLOSA_RS16545
uniprot id: D9R978
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

610130:CLOSA RS01410
gene id: 610130:CLOSA_RS01410
uniprot id: D9R214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05455
gene id: 610130:CLOSA_RS05455
uniprot id: D9R7E8
names: Similarity
messages: Belongs to the LOR family.

610130:CLOSA RS06475
gene id: 610130:CLOSA_RS06475
uniprot id: D9R8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

610130:CLOSA RS14715
gene id: 610130:CLOSA_RS14715
uniprot id: D9R739
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

610130:CLOSA RS09330
gene id: 610130:CLOSA_RS09330
uniprot id: D9QZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

610130:CLOSA RS20645
gene id: 610130:CLOSA_RS20645
uniprot id: D9R2J4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS10315
gene id: 610130:CLOSA_RS10315
uniprot id: D9R173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

610130:CLOSA RS19940
gene id: 610130:CLOSA_RS19940
uniprot id: D9R1G2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

610130:CLOSA RS09975
gene id: 610130:CLOSA_RS09975
uniprot id: D9R104
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

610130:CLOSA RS06860
gene id: 610130:CLOSA_RS06860
uniprot id: D9R8X2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS02000
gene id: 610130:CLOSA_RS02000
uniprot id: D9R328
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

610130:CLOSA RS03170
gene id: 610130:CLOSA_RS03170
uniprot id: D9R4R2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

610130:CLOSA RS06435
gene id: 610130:CLOSA_RS06435
uniprot id: D9R8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

610130:CLOSA RS12670
gene id: 610130:CLOSA_RS12670
uniprot id: D9R4X5
names: Similarity
messages: Belongs to the peptidase S11 family.

610130:CLOSA RS01200
gene id: 610130:CLOSA_RS01200
uniprot id: D9R1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

610130:CLOSA RS00430
gene id: 610130:CLOSA_RS00430
uniprot id: D9R0R9
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS12070
gene id: 610130:CLOSA_RS12070
uniprot id: D9R493
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS08955
gene id: 610130:CLOSA_RS08955
uniprot id: D9QZA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS19035
gene id: 610130:CLOSA_RS19035
uniprot id: D9QZS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

610130:CLOSA RS02055
gene id: 610130:CLOSA_RS02055
uniprot id: D9R339
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS04945
gene id: 610130:CLOSA_RS04945
uniprot id: D9R6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

610130:CLOSA RS07560
gene id: 610130:CLOSA_RS07560
uniprot id: D9R9N9
names: Similarity
messages: Belongs to the EutP/PduV family.

610130:CLOSA RS21065
gene id: 610130:CLOSA_RS21065
uniprot id: D9R3H9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

610130:CLOSA RS10540
gene id: 610130:CLOSA_RS10540
uniprot id: D9R1C0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS11000
gene id: 610130:CLOSA_RS11000
uniprot id: D9R2A7
names: Similarity
messages: Belongs to the peptidase A31 family.

610130:CLOSA RS00155
gene id: 610130:CLOSA_RS00155
uniprot id: D9R0L4
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS09525
gene id: 610130:CLOSA_RS09525
uniprot id: D9R012
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

610130:CLOSA RS07510
gene id: 610130:CLOSA_RS07510
uniprot id: D9R9M9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS08110
gene id: 610130:CLOSA_RS08110
uniprot id: D9RAB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

610130:CLOSA RS19500
gene id: 610130:CLOSA_RS19500
uniprot id: D9R0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS20880
gene id: 610130:CLOSA_RS20880
uniprot id: D9R2P0
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS11040
gene id: 610130:CLOSA_RS11040
uniprot id: D9R2B4
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

610130:CLOSA RS00625
gene id: 610130:CLOSA_RS00625
uniprot id: D9R0V9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

610130:CLOSA RS14780
gene id: 610130:CLOSA_RS14780
uniprot id: D9R752
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS02850
gene id: 610130:CLOSA_RS02850
uniprot id: D9R4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

610130:CLOSA RS08250
gene id: 610130:CLOSA_RS08250
uniprot id: D9RAE6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

610130:CLOSA RS01375
gene id: 610130:CLOSA_RS01375
uniprot id: D9R207
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS20105
gene id: 610130:CLOSA_RS20105
uniprot id: D9R1J4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

610130:CLOSA RS15120
gene id: 610130:CLOSA_RS15120
uniprot id: D9R7B9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10160
gene id: 610130:CLOSA_RS10160
uniprot id: D9R142
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

610130:CLOSA RS07740
gene id: 610130:CLOSA_RS07740
uniprot id: D9R9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

610130:CLOSA RS02540
gene id: 610130:CLOSA_RS02540
uniprot id: D9R414
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

610130:CLOSA RS03615
gene id: 610130:CLOSA_RS03615
uniprot id: D9R5B2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

610130:CLOSA RS00925
gene id: 610130:CLOSA_RS00925
uniprot id: D9R1S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

610130:CLOSA RS19695
gene id: 610130:CLOSA_RS19695
uniprot id: D9R0K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS05235
gene id: 610130:CLOSA_RS05235
uniprot id: D9R6X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

610130:CLOSA RS16815
gene id: 610130:CLOSA_RS16815
uniprot id: D9R9C7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS01875
gene id: 610130:CLOSA_RS01875
uniprot id: D9R306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

610130:CLOSA RS04670
gene id: 610130:CLOSA_RS04670
uniprot id: D9R689
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS18135
gene id: 610130:CLOSA_RS18135
uniprot id: D9RAT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS21545
gene id: 610130:CLOSA_RS21545
uniprot id: D9R3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

610130:CLOSA RS16745
gene id: 610130:CLOSA_RS16745
uniprot id: D9R9B7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

610130:CLOSA RS06800
gene id: 610130:CLOSA_RS06800
uniprot id: D9R8W1
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS06445
gene id: 610130:CLOSA_RS06445
uniprot id: D9R8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

610130:CLOSA RS08530
gene id: 610130:CLOSA_RS08530
uniprot id: D9RAK1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

610130:CLOSA RS04135
gene id: 610130:CLOSA_RS04135
uniprot id: D9R5Y7
names: Similarity
messages: Belongs to the peptidase S41A family.

610130:CLOSA RS07800
gene id: 610130:CLOSA_RS07800
uniprot id: D9R9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS02310
gene id: 610130:CLOSA_RS02310
uniprot id: D9R3W8
names: Similarity
messages: Belongs to the asparaginase 1 family.

610130:CLOSA RS13170
gene id: 610130:CLOSA_RS13170
uniprot id: D9R573
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS00655
gene id: 610130:CLOSA_RS00655
uniprot id: D9R0W5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

610130:CLOSA RS12445
gene id: 610130:CLOSA_RS12445
uniprot id: D9R4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

610130:CLOSA RS13795
gene id: 610130:CLOSA_RS13795
uniprot id: D9R5V9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS18815
gene id: 610130:CLOSA_RS18815
uniprot id: D9QZN2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

610130:CLOSA RS12495
gene id: 610130:CLOSA_RS12495
uniprot id: D9R4H6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

610130:CLOSA RS19165
gene id: 610130:CLOSA_RS19165
uniprot id: D9R096
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS04265
gene id: 610130:CLOSA_RS04265
uniprot id: D9R611
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

610130:CLOSA RS11965
gene id: 610130:CLOSA_RS11965
uniprot id: D9R472
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

610130:CLOSA RS09990
gene id: 610130:CLOSA_RS09990
uniprot id: D9R107
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

610130:CLOSA RS02530
gene id: 610130:CLOSA_RS02530
uniprot id: D9R412
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS12425
gene id: 610130:CLOSA_RS12425
uniprot id: D9R4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS16895
gene id: 610130:CLOSA_RS16895
uniprot id: D9R9E3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

610130:CLOSA RS12005
gene id: 610130:CLOSA_RS12005
uniprot id: D9R480
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS09100
gene id: 610130:CLOSA_RS09100
uniprot id: D9QZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

610130:CLOSA RS00375
gene id: 610130:CLOSA_RS00375
uniprot id: D9R0Q9
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

610130:CLOSA RS01245
gene id: 610130:CLOSA_RS01245
uniprot id: D9R1Y1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS02705
gene id: 610130:CLOSA_RS02705
uniprot id: D9R446
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

610130:CLOSA RS06490
gene id: 610130:CLOSA_RS06490
uniprot id: D9R8C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS20765
gene id: 610130:CLOSA_RS20765
uniprot id: D9R2L6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

610130:CLOSA RS21200
gene id: 610130:CLOSA_RS21200
uniprot id: D9R3K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

610130:CLOSA RS12140
gene id: 610130:CLOSA_RS12140
uniprot id: D9R4A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS12195
gene id: 610130:CLOSA_RS12195
uniprot id: D9R4B7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

610130:CLOSA RS15080
gene id: 610130:CLOSA_RS15080
uniprot id: D9R7B1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

610130:CLOSA RS11455
gene id: 610130:CLOSA_RS11455
uniprot id: D9R399
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS12945
gene id: 610130:CLOSA_RS12945
uniprot id: D9R529
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

610130:CLOSA RS21425
gene id: 610130:CLOSA_RS21425
uniprot id: D9R3P9
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10595
gene id: 610130:CLOSA_RS10595
uniprot id: D9R228
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

610130:CLOSA RS14660
gene id: 610130:CLOSA_RS14660
uniprot id: D9R728
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

610130:CLOSA RS18875
gene id: 610130:CLOSA_RS18875
uniprot id: D9QZP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

610130:CLOSA RS09660
gene id: 610130:CLOSA_RS09660
uniprot id: D9R037
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS19075
gene id: 610130:CLOSA_RS19075
uniprot id: D9QZT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

610130:CLOSA RS08590
gene id: 610130:CLOSA_RS08590
uniprot id: D9QZ41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

610130:CLOSA RS20525
gene id: 610130:CLOSA_RS20525
uniprot id: D9R2H1
names: Similarity
messages: Belongs to the peptidase M18 family.

610130:CLOSA RS18195
gene id: 610130:CLOSA_RS18195
uniprot id: D9RAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

610130:CLOSA RS18830
gene id: 610130:CLOSA_RS18830
uniprot id: D9QZN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

610130:CLOSA RS18035
gene id: 610130:CLOSA_RS18035
uniprot id: D9RAR1
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS05450
gene id: 610130:CLOSA_RS05450
uniprot id: D9R7E7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

610130:CLOSA RS05245
gene id: 610130:CLOSA_RS05245
uniprot id: D9R6X9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

610130:CLOSA RS07525
gene id: 610130:CLOSA_RS07525
uniprot id: D9R9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

610130:CLOSA RS18075
gene id: 610130:CLOSA_RS18075
uniprot id: D9RAR9
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

610130:CLOSA RS06730
gene id: 610130:CLOSA_RS06730
uniprot id: D9R8U7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS06610
gene id: 610130:CLOSA_RS06610
uniprot id: D9R8E7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS02165
gene id: 610130:CLOSA_RS02165
uniprot id: D9R3T8
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS11925
gene id: 610130:CLOSA_RS11925
uniprot id: D9R465
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

610130:CLOSA RS08080
gene id: 610130:CLOSA_RS08080
uniprot id: D9RAB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

610130:CLOSA RS20905
gene id: 610130:CLOSA_RS20905
uniprot id: D9R2P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

610130:CLOSA RS10745
gene id: 610130:CLOSA_RS10745
uniprot id: D9R258
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS01985
gene id: 610130:CLOSA_RS01985
uniprot id: D9R325
names: Similarity
messages: Belongs to the agmatine deiminase family.

610130:CLOSA RS00795
gene id: 610130:CLOSA_RS00795
uniprot id: D9R1Q1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

610130:CLOSA RS09625
gene id: 610130:CLOSA_RS09625
uniprot id: D9R031
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS04735
gene id: 610130:CLOSA_RS04735
uniprot id: D9R6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

610130:CLOSA RS13625
gene id: 610130:CLOSA_RS13625
uniprot id: D9R5T5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS00685
gene id: 610130:CLOSA_RS00685
uniprot id: D9R0X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

610130:CLOSA RS11805
gene id: 610130:CLOSA_RS11805
uniprot id: D9R3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

610130:CLOSA RS14395
gene id: 610130:CLOSA_RS14395
uniprot id: D9R6J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

610130:CLOSA RS02580
gene id: 610130:CLOSA_RS02580
uniprot id: D9R422
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS10790
gene id: 610130:CLOSA_RS10790
uniprot id: D9R267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

610130:CLOSA RS05295
gene id: 610130:CLOSA_RS05295
uniprot id: D9R6Y9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

610130:CLOSA RS09530
gene id: 610130:CLOSA_RS09530
uniprot id: D9R013
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

610130:CLOSA RS08690
gene id: 610130:CLOSA_RS08690
uniprot id: D9QZ61
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS12370
gene id: 610130:CLOSA_RS12370
uniprot id: D9R4F0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

610130:CLOSA RS14540
gene id: 610130:CLOSA_RS14540
uniprot id: D9R705
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

610130:CLOSA RS07960
gene id: 610130:CLOSA_RS07960
uniprot id: D9RA89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS03225
gene id: 610130:CLOSA_RS03225
uniprot id: D9R4S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

610130:CLOSA RS09150
gene id: 610130:CLOSA_RS09150
uniprot id: D9QZE2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

610130:CLOSA RS20665
gene id: 610130:CLOSA_RS20665
uniprot id: D9R2J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

610130:CLOSA RS04770
gene id: 610130:CLOSA_RS04770
uniprot id: D9R6N7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

610130:CLOSA RS13390
gene id: 610130:CLOSA_RS13390
uniprot id: D9R5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

610130:CLOSA RS08700
gene id: 610130:CLOSA_RS08700
uniprot id: D9QZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS12160
gene id: 610130:CLOSA_RS12160
uniprot id: D9R4B2
names: Similarity
messages: Belongs to the CobT family.

610130:CLOSA RS14390
gene id: 610130:CLOSA_RS14390
uniprot id: D9R6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

610130:CLOSA RS13030
gene id: 610130:CLOSA_RS13030
uniprot id: D9R545
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

610130:CLOSA RS19325
gene id: 610130:CLOSA_RS19325
uniprot id: D9R0C8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

610130:CLOSA RS19980
gene id: 610130:CLOSA_RS19980
uniprot id: D9R1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS18345
gene id: 610130:CLOSA_RS18345
uniprot id: D9RAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS00680
gene id: 610130:CLOSA_RS00680
uniprot id: D9R0X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

610130:CLOSA RS01625
gene id: 610130:CLOSA_RS01625
uniprot id: D9R2V8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

610130:CLOSA RS14755
gene id: 610130:CLOSA_RS14755
uniprot id: D9R747
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS00630
gene id: 610130:CLOSA_RS00630
uniprot id: D9R0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

610130:CLOSA RS17355
gene id: 610130:CLOSA_RS17355
uniprot id: D9RA04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

610130:CLOSA RS21370
gene id: 610130:CLOSA_RS21370
uniprot id: D9R3N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

610130:CLOSA RS13195
gene id: 610130:CLOSA_RS13195
uniprot id: D9R5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

610130:CLOSA RS13640
gene id: 610130:CLOSA_RS13640
uniprot id: D9R5T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

610130:CLOSA RS12470
gene id: 610130:CLOSA_RS12470
uniprot id: D9R4H0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

610130:CLOSA RS12035
gene id: 610130:CLOSA_RS12035
uniprot id: D9R486
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

610130:CLOSA RS03595
gene id: 610130:CLOSA_RS03595
uniprot id: D9R5A8
names: Similarity
messages: Belongs to the peptidase C40 family.

610130:CLOSA RS02770
gene id: 610130:CLOSA_RS02770
uniprot id: D9R4I7
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS12980
gene id: 610130:CLOSA_RS12980
uniprot id: D9R535
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS14730
gene id: 610130:CLOSA_RS14730
uniprot id: D9R742
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

610130:CLOSA RS11260
gene id: 610130:CLOSA_RS11260
uniprot id: D9R361
names: Similarity
messages: Belongs to the Nudix hydrolase family.

610130:CLOSA RS11120
gene id: 610130:CLOSA_RS11120
uniprot id: D9R2D0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

610130:CLOSA RS17440
gene id: 610130:CLOSA_RS17440
uniprot id: D9RA20
names: Subcellular Location Annotation
messages: Cytoplasm

610130:CLOSA RS01615
gene id: 610130:CLOSA_RS01615
uniprot id: D9R2V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

610130:CLOSA RS20225
gene id: 610130:CLOSA_RS20225
uniprot id: D9R1L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

610130:CLOSA RS05785
gene id: 610130:CLOSA_RS05785
uniprot id: D9R7L4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

610130:CLOSA RS09845
gene id: 610130:CLOSA_RS09845
uniprot id: D9R073
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

610130:CLOSA RS11615
gene id: 610130:CLOSA_RS11615
uniprot id: D9R3C5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

610130:CLOSA RS21525
gene id: 610130:CLOSA_RS21525
uniprot id: D9R3R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

610130:CLOSA RS18835
gene id: 610130:CLOSA_RS18835
uniprot id: D9QZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

610130:CLOSA RS09325
gene id: 610130:CLOSA_RS09325
uniprot id: D9QZX8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

610130:CLOSA RS03200
gene id: 610130:CLOSA_RS03200
uniprot id: D9R4R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

610130:CLOSA RS00935
gene id: 610130:CLOSA_RS00935
uniprot id: D9R1S8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

610130:CLOSA RS02730
gene id: 610130:CLOSA_RS02730
uniprot id: D9R451
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

610130:CLOSA RS20910
gene id: 610130:CLOSA_RS20910
uniprot id: D9R2P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

610130:CLOSA RS03140
gene id: 610130:CLOSA_RS03140
uniprot id: D9R4Q6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

610130:CLOSA RS18940
gene id: 610130:CLOSA_RS18940
uniprot id: D9QZQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

610130:CLOSA RS06320
gene id: 610130:CLOSA_RS06320
uniprot id: D9R892
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

610130:CLOSA RS10615
gene id: 610130:CLOSA_RS10615
uniprot id: D9R232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

610130:CLOSA RS19895
gene id: 610130:CLOSA_RS19895
uniprot id: D9R1F3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).

610130:CLOSA RS18950
gene id: 610130:CLOSA_RS18950
uniprot id: D9QZR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

610130:CLOSA RS09115
gene id: 610130:CLOSA_RS09115
uniprot id: D9QZD5
names: Similarity
messages: Belongs to the sigma-54 factor family.

610130:CLOSA RS20860
gene id: 610130:CLOSA_RS20860
uniprot id: D9R2N6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

610130:CLOSA RS08145
gene id: 610130:CLOSA_RS08145
uniprot id: D9RAC6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

610130:CLOSA RS17520
gene id: 610130:CLOSA_RS17520
uniprot id: D9RA36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

610130:CLOSA RS00620
gene id: 610130:CLOSA_RS00620
uniprot id: D9R0V8
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS20920
gene id: 610130:CLOSA_RS20920
uniprot id: D9R2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

610130:CLOSA RS19370
gene id: 610130:CLOSA_RS19370
uniprot id: D9R0D8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

610130:CLOSA RS04835
gene id: 610130:CLOSA_RS04835
uniprot id: D9R6Q0
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

610130:CLOSA RS01345
gene id: 610130:CLOSA_RS01345
uniprot id: D9R201
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

610130:CLOSA RS06165
gene id: 610130:CLOSA_RS06165
uniprot id: D9R863
names: Subcellular Location Annotation
messages: Membrane

610130:CLOSA RS07265
gene id: 610130:CLOSA_RS07265
uniprot id: D9R956
names: Similarity
messages: Belongs to the peptidase S8 family.

610130:CLOSA RS12675
gene id: 610130:CLOSA_RS12675
uniprot id: D9R4X6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

610130:CLOSA RS11145
gene id: 610130:CLOSA_RS11145
uniprot id: D9R2D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

610130:CLOSA RS19020
gene id: 610130:CLOSA_RS19020
uniprot id: D9QZS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

610130:CLOSA RS20555
gene id: 610130:CLOSA_RS20555
uniprot id: D9R2H7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

610130:CLOSA RS16935
gene id: 610130:CLOSA_RS16935
uniprot id: D9R9F1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

610130:CLOSA RS12430
gene id: 610130:CLOSA_RS12430
uniprot id: D9R4G2
names: Similarity
messages: Belongs to the transpeptidase family.

610130:CLOSA RS04300
gene id: 610130:CLOSA_RS04300
uniprot id: D9R618
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

610130:CLOSA RS07910
gene id: 610130:CLOSA_RS07910
uniprot id: D9R9V6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

610130:CLOSA RS11595
gene id: 610130:CLOSA_RS11595
uniprot id: D9R3C1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.