59505:FB03 RS06215
gene id: 59505:FB03_RS06215
uniprot id: A0A068NHI2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

59505:FB03 RS02355
gene id: 59505:FB03_RS02355
uniprot id: A0A068NFR5
names: Similarity
messages: Belongs to the HSP15 family.

59505:FB03 RS03845
gene id: 59505:FB03_RS03845
uniprot id: A0A068NG51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

59505:FB03 RS00750
gene id: 59505:FB03_RS00750
uniprot id: A0A068NEZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

59505:FB03 RS08635
gene id: 59505:FB03_RS08635
uniprot id: A0A068NP11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS04060
gene id: 59505:FB03_RS04060
uniprot id: A0A068NM83
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

59505:FB03 RS03640
gene id: 59505:FB03_RS03640
uniprot id: A0A068NGE8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS00865
gene id: 59505:FB03_RS00865
uniprot id: A0A068NF65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

59505:FB03 RS05940
gene id: 59505:FB03_RS05940
uniprot id: A0A068NH74
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS02520
gene id: 59505:FB03_RS02520
uniprot id: A0A068NFU6
names: Similarity
messages: Belongs to the UPF0098 family.

59505:FB03 RS06440
gene id: 59505:FB03_RS06440
uniprot id: A0A068NN55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

59505:FB03 RS02990
gene id: 59505:FB03_RS02990
uniprot id: A0A068NFW9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

59505:FB03 RS01565
gene id: 59505:FB03_RS01565
uniprot id: A0A068NFE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

59505:FB03 RS07960
gene id: 59505:FB03_RS07960
uniprot id: A0A068NIB2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

59505:FB03 RS06385
gene id: 59505:FB03_RS06385
uniprot id: A0A068NH66
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS08655
gene id: 59505:FB03_RS08655
uniprot id: A0A068NIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

59505:FB03 RS08020
gene id: 59505:FB03_RS08020
uniprot id: A0A068NNS5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

59505:FB03 RS02865
gene id: 59505:FB03_RS02865
uniprot id: A0A068NFU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS03105
gene id: 59505:FB03_RS03105
uniprot id: A0A068NLS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

59505:FB03 RS04770
gene id: 59505:FB03_RS04770
uniprot id: A0A068NGX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

59505:FB03 RS03000
gene id: 59505:FB03_RS03000
uniprot id: A0A068NFL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

59505:FB03 RS05255
gene id: 59505:FB03_RS05255
uniprot id: A0A068NGL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59505:FB03 RS03270
gene id: 59505:FB03_RS03270
uniprot id: A0A068NG17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

59505:FB03 RS01280
gene id: 59505:FB03_RS01280
uniprot id: A0A068NF54
names: Similarity
messages: Belongs to the glutamine synthetase family.

59505:FB03 RS02750
gene id: 59505:FB03_RS02750
uniprot id: A0A068NLL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

59505:FB03 RS00305
gene id: 59505:FB03_RS00305
uniprot id: A0A068NEN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59505:FB03 RS01235
gene id: 59505:FB03_RS01235
uniprot id: A0A068NFA4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

59505:FB03 RS01965
gene id: 59505:FB03_RS01965
uniprot id: A0A068NF29
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

59505:FB03 RS07920
gene id: 59505:FB03_RS07920
uniprot id: A0A068NIA8
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS06465
gene id: 59505:FB03_RS06465
uniprot id: A0A068NH80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

59505:FB03 RS08590
gene id: 59505:FB03_RS08590
uniprot id: A0A068NI57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

59505:FB03 RS00475
gene id: 59505:FB03_RS00475
uniprot id: A0A068NGZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

59505:FB03 RS08940
gene id: 59505:FB03_RS08940
uniprot id: A0A068NIB4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

59505:FB03 RS08255
gene id: 59505:FB03_RS08255
uniprot id: A0A068NNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

59505:FB03 RS03835
gene id: 59505:FB03_RS03835
uniprot id: A0A068NGE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

59505:FB03 RS05280
gene id: 59505:FB03_RS05280
uniprot id: A0A068NH45
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

59505:FB03 RS05950
gene id: 59505:FB03_RS05950
uniprot id: A0A068NGY9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

59505:FB03 RS02975
gene id: 59505:FB03_RS02975
uniprot id: A0A068NFL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

59505:FB03 RS00900
gene id: 59505:FB03_RS00900
uniprot id: A0A068NKW4
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS05985
gene id: 59505:FB03_RS05985
uniprot id: A0A068NJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS06610
gene id: 59505:FB03_RS06610
uniprot id: A0A068NHR5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

59505:FB03 RS02320
gene id: 59505:FB03_RS02320
uniprot id: A0A068NFR0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

59505:FB03 RS00505
gene id: 59505:FB03_RS00505
uniprot id: A0A068NKQ0
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

59505:FB03 RS07165
gene id: 59505:FB03_RS07165
uniprot id: A0A068NHL7
names: Subcellular Location Annotation
messages: Cell membrane

59505:FB03 RS00625
gene id: 59505:FB03_RS00625
uniprot id: A0A068NKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

59505:FB03 RS05375
gene id: 59505:FB03_RS05375
uniprot id: A0A068NGY8
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

59505:FB03 RS08700
gene id: 59505:FB03_RS08700
uniprot id: A0A068NKK8
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS06880
gene id: 59505:FB03_RS06880
uniprot id: A0A068NHZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

59505:FB03 RS07460
gene id: 59505:FB03_RS07460
uniprot id: A0A068NHQ3
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

59505:FB03 RS04660
gene id: 59505:FB03_RS04660
uniprot id: A0A068NIY5
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS02795
gene id: 59505:FB03_RS02795
uniprot id: A0A068NFH5
names: Similarity
messages: Belongs to the FPG family.

59505:FB03 RS05860
gene id: 59505:FB03_RS05860
uniprot id: A0A068NMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

59505:FB03 RS03945
gene id: 59505:FB03_RS03945
uniprot id: A0A068NGM6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

59505:FB03 RS08670
gene id: 59505:FB03_RS08670
uniprot id: A0A068NKK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

59505:FB03 RS04265
gene id: 59505:FB03_RS04265
uniprot id: A0A068NIU6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

59505:FB03 RS02235
gene id: 59505:FB03_RS02235
uniprot id: A0A068NFP7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

59505:FB03 RS04435
gene id: 59505:FB03_RS04435
uniprot id: A0A068NIW4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

59505:FB03 RS01645
gene id: 59505:FB03_RS01645
uniprot id: A0A068NFG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS00940
gene id: 59505:FB03_RS00940
uniprot id: A0A068NHA4
names: Similarity
messages: Belongs to the YggT family.

59505:FB03 RS04955
gene id: 59505:FB03_RS04955
uniprot id: A0A068NGI0
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS04210
gene id: 59505:FB03_RS04210
uniprot id: A0A068NIT9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

59505:FB03 RS02000
gene id: 59505:FB03_RS02000
uniprot id: A0A068NHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

59505:FB03 RS02345
gene id: 59505:FB03_RS02345
uniprot id: A0A068NHT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

59505:FB03 RS01045
gene id: 59505:FB03_RS01045
uniprot id: A0A068NF85
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

59505:FB03 RS08840
gene id: 59505:FB03_RS08840
uniprot id: A0A068NIP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

59505:FB03 RS08300
gene id: 59505:FB03_RS08300
uniprot id: A0A068NI05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

59505:FB03 RS04235
gene id: 59505:FB03_RS04235
uniprot id: A0A068NIU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

59505:FB03 RS03960
gene id: 59505:FB03_RS03960
uniprot id: A0A068NM74
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

59505:FB03 RS03745
gene id: 59505:FB03_RS03745
uniprot id: A0A068NG25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

59505:FB03 RS02765
gene id: 59505:FB03_RS02765
uniprot id: A0A068NFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

59505:FB03 RS03785
gene id: 59505:FB03_RS03785
uniprot id: A0A068NGD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

59505:FB03 RS07140
gene id: 59505:FB03_RS07140
uniprot id: A0A068NK39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

59505:FB03 RS01260
gene id: 59505:FB03_RS01260
uniprot id: A0A068NFA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

59505:FB03 RS00270
gene id: 59505:FB03_RS00270
uniprot id: A0A068NGV7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

59505:FB03 RS00215
gene id: 59505:FB03_RS00215
uniprot id: A0A068NGU6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

59505:FB03 RS02415
gene id: 59505:FB03_RS02415
uniprot id: A0A068NLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS03890
gene id: 59505:FB03_RS03890
uniprot id: A0A068NGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

59505:FB03 RS02405
gene id: 59505:FB03_RS02405
uniprot id: A0A068NFS3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

59505:FB03 RS08095
gene id: 59505:FB03_RS08095
uniprot id: A0A068NKD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

59505:FB03 RS01985
gene id: 59505:FB03_RS01985
uniprot id: A0A068NFK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

59505:FB03 RS03495
gene id: 59505:FB03_RS03495
uniprot id: A0A068NFV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

59505:FB03 RS01835
gene id: 59505:FB03_RS01835
uniprot id: A0A068NL77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

59505:FB03 RS03480
gene id: 59505:FB03_RS03480
uniprot id: A0A068NIE3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS01345
gene id: 59505:FB03_RS01345
uniprot id: A0A068NL19
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

59505:FB03 RS02100
gene id: 59505:FB03_RS02100
uniprot id: A0A068NLB3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

59505:FB03 RS03770
gene id: 59505:FB03_RS03770
uniprot id: A0A068NG38
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

59505:FB03 RS04785
gene id: 59505:FB03_RS04785
uniprot id: A0A068NJ01
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

59505:FB03 RS03695
gene id: 59505:FB03_RS03695
uniprot id: A0A068NII8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

59505:FB03 RS03720
gene id: 59505:FB03_RS03720
uniprot id: A0A068NG00
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

59505:FB03 RS01635
gene id: 59505:FB03_RS01635
uniprot id: A0A068NHI5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

59505:FB03 RS06490
gene id: 59505:FB03_RS06490
uniprot id: A0A068NHP5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

59505:FB03 RS08170
gene id: 59505:FB03_RS08170
uniprot id: A0A068NIE5
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS03485
gene id: 59505:FB03_RS03485
uniprot id: A0A068NG50
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

59505:FB03 RS05525
gene id: 59505:FB03_RS05525
uniprot id: A0A068NJ94
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

59505:FB03 RS00690
gene id: 59505:FB03_RS00690
uniprot id: A0A068NEW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

59505:FB03 RS08005
gene id: 59505:FB03_RS08005
uniprot id: A0A068NI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

59505:FB03 RS04490
gene id: 59505:FB03_RS04490
uniprot id: A0A068NIX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

59505:FB03 RS03190
gene id: 59505:FB03_RS03190
uniprot id: A0A068NG64
names: Similarity
messages: Belongs to the DEAD box helicase family.

59505:FB03 RS08495
gene id: 59505:FB03_RS08495
uniprot id: A0A068NID8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

59505:FB03 RS07665
gene id: 59505:FB03_RS07665
uniprot id: A0A068NI19
names: Similarity
messages: Belongs to the peptidase C1 family.

59505:FB03 RS00815
gene id: 59505:FB03_RS00815
uniprot id: A0A068NH89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

59505:FB03 RS04205
gene id: 59505:FB03_RS04205
uniprot id: A0A068NMA0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

59505:FB03 RS08405
gene id: 59505:FB03_RS08405
uniprot id: A0A068NIC1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

59505:FB03 RS03940
gene id: 59505:FB03_RS03940
uniprot id: A0A068NGF8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

59505:FB03 RS08265
gene id: 59505:FB03_RS08265
uniprot id: A0A068NI96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

59505:FB03 RS03700
gene id: 59505:FB03_RS03700
uniprot id: A0A068NG96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

59505:FB03 RS08195
gene id: 59505:FB03_RS08195
uniprot id: A0A068NNU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

59505:FB03 RS00925
gene id: 59505:FB03_RS00925
uniprot id: A0A068NEQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

59505:FB03 RS06470
gene id: 59505:FB03_RS06470
uniprot id: A0A068NN61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

59505:FB03 RS04980
gene id: 59505:FB03_RS04980
uniprot id: A0A068NH04
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

59505:FB03 RS04390
gene id: 59505:FB03_RS04390
uniprot id: A0A068NMC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

59505:FB03 RS08860
gene id: 59505:FB03_RS08860
uniprot id: A0A068NKN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

59505:FB03 RS07825
gene id: 59505:FB03_RS07825
uniprot id: A0A068NNQ3
names: Similarity
messages: Belongs to the peptidase C40 family.

59505:FB03 RS08230
gene id: 59505:FB03_RS08230
uniprot id: A0A068NKE7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

59505:FB03 RS00360
gene id: 59505:FB03_RS00360
uniprot id: A0A068NEV3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

59505:FB03 RS01455
gene id: 59505:FB03_RS01455
uniprot id: A0A068NEX2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

59505:FB03 RS03820
gene id: 59505:FB03_RS03820
uniprot id: A0A068NG48
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

59505:FB03 RS01300
gene id: 59505:FB03_RS01300
uniprot id: A0A068NHE6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

59505:FB03 RS08015
gene id: 59505:FB03_RS08015
uniprot id: A0A068NHW6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

59505:FB03 RS00520
gene id: 59505:FB03_RS00520
uniprot id: A0A068NEY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

59505:FB03 RS07095
gene id: 59505:FB03_RS07095
uniprot id: A0A068NHV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

59505:FB03 RS06915
gene id: 59505:FB03_RS06915
uniprot id: A0A068NHJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

59505:FB03 RS02850
gene id: 59505:FB03_RS02850
uniprot id: A0A068NLN5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

59505:FB03 RS06290
gene id: 59505:FB03_RS06290
uniprot id: A0A068NJL0
names: Similarity
messages: Belongs to the peptidase S33 family.

59505:FB03 RS07610
gene id: 59505:FB03_RS07610
uniprot id: A0A068NK81
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

59505:FB03 RS02845
gene id: 59505:FB03_RS02845
uniprot id: A0A068NFI6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59505:FB03 RS05135
gene id: 59505:FB03_RS05135
uniprot id: A0A068NH26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

59505:FB03 RS04680
gene id: 59505:FB03_RS04680
uniprot id: A0A068NMF2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

59505:FB03 RS08110
gene id: 59505:FB03_RS08110
uniprot id: A0A068NHX7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

59505:FB03 RS01745
gene id: 59505:FB03_RS01745
uniprot id: A0A068NHJ8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

59505:FB03 RS08210
gene id: 59505:FB03_RS08210
uniprot id: A0A068NIF1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

59505:FB03 RS08280
gene id: 59505:FB03_RS08280
uniprot id: A0A068NNW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

59505:FB03 RS06840
gene id: 59505:FB03_RS06840
uniprot id: A0A068NNB9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

59505:FB03 RS00995
gene id: 59505:FB03_RS00995
uniprot id: A0A068NF79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

59505:FB03 RS08830
gene id: 59505:FB03_RS08830
uniprot id: A0A068NKM8
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

59505:FB03 RS04510
gene id: 59505:FB03_RS04510
uniprot id: A0A068NGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS08225
gene id: 59505:FB03_RS08225
uniprot id: A0A068NNV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

59505:FB03 RS02010
gene id: 59505:FB03_RS02010
uniprot id: A0A068NFL2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

59505:FB03 RS03245
gene id: 59505:FB03_RS03245
uniprot id: A0A068NG77
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS00965
gene id: 59505:FB03_RS00965
uniprot id: A0A068NKX0
names: Subcellular Location Annotation
messages: Cytoplasm

59505:FB03 RS03935
gene id: 59505:FB03_RS03935
uniprot id: A0A068NIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

59505:FB03 RS02095
gene id: 59505:FB03_RS02095
uniprot id: A0A068NF48
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

59505:FB03 RS03905
gene id: 59505:FB03_RS03905
uniprot id: A0A068NM67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

59505:FB03 RS03460
gene id: 59505:FB03_RS03460
uniprot id: A0A068NG45
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

59505:FB03 RS00680
gene id: 59505:FB03_RS00680
uniprot id: A0A068NH40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

59505:FB03 RS01050
gene id: 59505:FB03_RS01050
uniprot id: A0A068NES1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

59505:FB03 RS01770
gene id: 59505:FB03_RS01770
uniprot id: A0A068NF04
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS02870
gene id: 59505:FB03_RS02870
uniprot id: A0A068NG09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

59505:FB03 RS01550
gene id: 59505:FB03_RS01550
uniprot id: A0A068NL42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

59505:FB03 RS02005
gene id: 59505:FB03_RS02005
uniprot id: A0A068NFE9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

59505:FB03 RS04705
gene id: 59505:FB03_RS04705
uniprot id: A0A068NGF1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

59505:FB03 RS05075
gene id: 59505:FB03_RS05075
uniprot id: A0A068NH18
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

59505:FB03 RS00635
gene id: 59505:FB03_RS00635
uniprot id: A0A068NEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

59505:FB03 RS06025
gene id: 59505:FB03_RS06025
uniprot id: A0A068NMY3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

59505:FB03 RS01560
gene id: 59505:FB03_RS01560
uniprot id: A0A068NF90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

59505:FB03 RS02420
gene id: 59505:FB03_RS02420
uniprot id: A0A068NHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

59505:FB03 RS01685
gene id: 59505:FB03_RS01685
uniprot id: A0A068NFA5
names: Similarity
messages: Belongs to the TlyA family.

59505:FB03 RS02335
gene id: 59505:FB03_RS02335
uniprot id: A0A068NLE5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS06330
gene id: 59505:FB03_RS06330
uniprot id: A0A068NH56
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

59505:FB03 RS04610
gene id: 59505:FB03_RS04610
uniprot id: A0A068NGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

59505:FB03 RS03865
gene id: 59505:FB03_RS03865
uniprot id: A0A068NGL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

59505:FB03 RS00185
gene id: 59505:FB03_RS00185
uniprot id: A0A068NKJ6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

59505:FB03 RS00525
gene id: 59505:FB03_RS00525
uniprot id: A0A068NEG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

59505:FB03 RS04835
gene id: 59505:FB03_RS04835
uniprot id: A0A068NJ05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

59505:FB03 RS08165
gene id: 59505:FB03_RS08165
uniprot id: A0A068NI81
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS01895
gene id: 59505:FB03_RS01895
uniprot id: A0A068NFJ4
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

59505:FB03 RS03735
gene id: 59505:FB03_RS03735
uniprot id: A0A068NGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

59505:FB03 RS03250
gene id: 59505:FB03_RS03250
uniprot id: A0A068NFQ9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

59505:FB03 RS01785
gene id: 59505:FB03_RS01785
uniprot id: A0A068NFB7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS04780
gene id: 59505:FB03_RS04780
uniprot id: A0A068NMG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

59505:FB03 RS00695
gene id: 59505:FB03_RS00695
uniprot id: A0A068NF39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

59505:FB03 RS04665
gene id: 59505:FB03_RS04665
uniprot id: A0A068NGP3
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS01580
gene id: 59505:FB03_RS01580
uniprot id: A0A068NL46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

59505:FB03 RS00275
gene id: 59505:FB03_RS00275
uniprot id: A0A068NEM6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

59505:FB03 RS05740
gene id: 59505:FB03_RS05740
uniprot id: A0A068NMU4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

59505:FB03 RS01405
gene id: 59505:FB03_RS01405
uniprot id: A0A068NL25
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

59505:FB03 RS00905
gene id: 59505:FB03_RS00905
uniprot id: A0A068NHA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS00880
gene id: 59505:FB03_RS00880
uniprot id: A0A068NH96
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS01805
gene id: 59505:FB03_RS01805
uniprot id: A0A068NHK7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

59505:FB03 RS03925
gene id: 59505:FB03_RS03925
uniprot id: A0A068NG63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

59505:FB03 RS04010
gene id: 59505:FB03_RS04010
uniprot id: A0A068NIR2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

59505:FB03 RS08915
gene id: 59505:FB03_RS08915
uniprot id: A0A068NP50
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

59505:FB03 RS01900
gene id: 59505:FB03_RS01900
uniprot id: A0A068NF21
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

59505:FB03 RS03765
gene id: 59505:FB03_RS03765
uniprot id: A0A068NGK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

59505:FB03 RS06135
gene id: 59505:FB03_RS06135
uniprot id: A0A068NJI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

59505:FB03 RS05570
gene id: 59505:FB03_RS05570
uniprot id: A0A068NH82
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

59505:FB03 RS07195
gene id: 59505:FB03_RS07195
uniprot id: A0A068NNI8
names: Similarity
messages: Belongs to the fructosamine kinase family.

59505:FB03 RS00650
gene id: 59505:FB03_RS00650
uniprot id: A0A068NKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

59505:FB03 RS02665
gene id: 59505:FB03_RS02665
uniprot id: A0A068NFR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

59505:FB03 RS02570
gene id: 59505:FB03_RS02570
uniprot id: A0A068NHW8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

59505:FB03 RS02360
gene id: 59505:FB03_RS02360
uniprot id: A0A068NF96
names: Similarity
messages: Belongs to the NusB family.

59505:FB03 RS00180
gene id: 59505:FB03_RS00180
uniprot id: A0A068NEB0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

59505:FB03 RS05475
gene id: 59505:FB03_RS05475
uniprot id: A0A068NH69
names: Similarity
messages: Belongs to the IlvD/Edd family.

59505:FB03 RS00210
gene id: 59505:FB03_RS00210
uniprot id: A0A068NKK1
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS00265
gene id: 59505:FB03_RS00265
uniprot id: A0A068NKL1
names: Similarity
messages: Belongs to the peptidase M13 family.

59505:FB03 RS03455
gene id: 59505:FB03_RS03455
uniprot id: A0A068NID6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

59505:FB03 RS02800
gene id: 59505:FB03_RS02800
uniprot id: A0A068NLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

59505:FB03 RS04385
gene id: 59505:FB03_RS04385
uniprot id: A0A068NGB6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

59505:FB03 RS03350
gene id: 59505:FB03_RS03350
uniprot id: A0A068NFS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

59505:FB03 RS06410
gene id: 59505:FB03_RS06410
uniprot id: A0A068NH71
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

59505:FB03 RS00630
gene id: 59505:FB03_RS00630
uniprot id: A0A068NH27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

59505:FB03 RS02525
gene id: 59505:FB03_RS02525
uniprot id: A0A068NFC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

59505:FB03 RS08305
gene id: 59505:FB03_RS08305
uniprot id: A0A068NNW3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

59505:FB03 RS08825
gene id: 59505:FB03_RS08825
uniprot id: A0A068NP38
names: Similarity
messages: Belongs to the UPF0237 family.

59505:FB03 RS06335
gene id: 59505:FB03_RS06335
uniprot id: A0A068NN35
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS03965
gene id: 59505:FB03_RS03965
uniprot id: A0A068NIQ8
names: Similarity
messages: Belongs to the alkaline phosphatase family.

59505:FB03 RS02485
gene id: 59505:FB03_RS02485
uniprot id: A0A068NFB8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

59505:FB03 RS00220
gene id: 59505:FB03_RS00220
uniprot id: A0A068NEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

59505:FB03 RS05305
gene id: 59505:FB03_RS05305
uniprot id: A0A068NH50
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59505:FB03 RS06350
gene id: 59505:FB03_RS06350
uniprot id: A0A068NHL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

59505:FB03 RS08735
gene id: 59505:FB03_RS08735
uniprot id: A0A068NIH7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

59505:FB03 RS06530
gene id: 59505:FB03_RS06530
uniprot id: A0A068NH93
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

59505:FB03 RS03910
gene id: 59505:FB03_RS03910
uniprot id: A0A068NIQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

59505:FB03 RS02065
gene id: 59505:FB03_RS02065
uniprot id: A0A068NF44
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

59505:FB03 RS07500
gene id: 59505:FB03_RS07500
uniprot id: A0A068NNM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS00080
gene id: 59505:FB03_RS00080
uniprot id: A0A068NEP9
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

59505:FB03 RS05585
gene id: 59505:FB03_RS05585
uniprot id: A0A068NJA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

59505:FB03 RS02725
gene id: 59505:FB03_RS02725
uniprot id: A0A068NHZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

59505:FB03 RS06635
gene id: 59505:FB03_RS06635
uniprot id: A0A068NHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

59505:FB03 RS03985
gene id: 59505:FB03_RS03985
uniprot id: A0A068NG68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

59505:FB03 RS04495
gene id: 59505:FB03_RS04495
uniprot id: A0A068NGL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

59505:FB03 RS07480
gene id: 59505:FB03_RS07480
uniprot id: A0A068NHZ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS04720
gene id: 59505:FB03_RS04720
uniprot id: A0A068NGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

59505:FB03 RS00745
gene id: 59505:FB03_RS00745
uniprot id: A0A068NH81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

59505:FB03 RS00145
gene id: 59505:FB03_RS00145
uniprot id: A0A068NEA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS01590
gene id: 59505:FB03_RS01590
uniprot id: A0A068NF94
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

59505:FB03 RS01695
gene id: 59505:FB03_RS01695
uniprot id: A0A068NEZ5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

59505:FB03 RS02455
gene id: 59505:FB03_RS02455
uniprot id: A0A068NFT4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

59505:FB03 RS06950
gene id: 59505:FB03_RS06950
uniprot id: A0A068NHZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

59505:FB03 RS05260
gene id: 59505:FB03_RS05260
uniprot id: A0A068NMN1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

59505:FB03 RS03920
gene id: 59505:FB03_RS03920
uniprot id: A0A068NGM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

59505:FB03 RS03235
gene id: 59505:FB03_RS03235
uniprot id: A0A068NI90
names: Similarity
messages: Belongs to the LOG family.

59505:FB03 RS07040
gene id: 59505:FB03_RS07040
uniprot id: A0A068NK28
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

59505:FB03 RS03515
gene id: 59505:FB03_RS03515
uniprot id: A0A068NLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

59505:FB03 RS02400
gene id: 59505:FB03_RS02400
uniprot id: A0A068NFL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

59505:FB03 RS04605
gene id: 59505:FB03_RS04605
uniprot id: A0A068NGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

59505:FB03 RS01750
gene id: 59505:FB03_RS01750
uniprot id: A0A068NFB3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

59505:FB03 RS05550
gene id: 59505:FB03_RS05550
uniprot id: A0A068NJ99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

59505:FB03 RS01160
gene id: 59505:FB03_RS01160
uniprot id: A0A068NKZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

59505:FB03 RS08835
gene id: 59505:FB03_RS08835
uniprot id: A0A068NIJ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

59505:FB03 RS01955
gene id: 59505:FB03_RS01955
uniprot id: A0A068NFD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

59505:FB03 RS08390
gene id: 59505:FB03_RS08390
uniprot id: A0A068NI20
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

59505:FB03 RS02895
gene id: 59505:FB03_RS02895
uniprot id: A0A068NI27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

59505:FB03 RS01930
gene id: 59505:FB03_RS01930
uniprot id: A0A068NFJ7
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

59505:FB03 RS07720
gene id: 59505:FB03_RS07720
uniprot id: A0A068NK91
names: Similarity
messages: Belongs to the FPG family.

59505:FB03 RS07160
gene id: 59505:FB03_RS07160
uniprot id: A0A068NI25
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS03415
gene id: 59505:FB03_RS03415
uniprot id: A0A068NFT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

59505:FB03 RS00885
gene id: 59505:FB03_RS00885
uniprot id: A0A068NF09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

59505:FB03 RS03430
gene id: 59505:FB03_RS03430
uniprot id: A0A068NG40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS02840
gene id: 59505:FB03_RS02840
uniprot id: A0A068NG05
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS08285
gene id: 59505:FB03_RS08285
uniprot id: A0A068NKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

59505:FB03 RS00760
gene id: 59505:FB03_RS00760
uniprot id: A0A068NEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

59505:FB03 RS03275
gene id: 59505:FB03_RS03275
uniprot id: A0A068NG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

59505:FB03 RS03900
gene id: 59505:FB03_RS03900
uniprot id: A0A068NG58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

59505:FB03 RS03805
gene id: 59505:FB03_RS03805
uniprot id: A0A068NIN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

59505:FB03 RS05055
gene id: 59505:FB03_RS05055
uniprot id: A0A068NGJ1
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS05960
gene id: 59505:FB03_RS05960
uniprot id: A0A068NJF9
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

59505:FB03 RS03790
gene id: 59505:FB03_RS03790
uniprot id: A0A068NGK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

59505:FB03 RS05120
gene id: 59505:FB03_RS05120
uniprot id: A0A068NJ45
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59505:FB03 RS04300
gene id: 59505:FB03_RS04300
uniprot id: A0A068NGJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS06825
gene id: 59505:FB03_RS06825
uniprot id: A0A068NHN7
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

59505:FB03 RS03725
gene id: 59505:FB03_RS03725
uniprot id: A0A068NM21
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

59505:FB03 RS03850
gene id: 59505:FB03_RS03850
uniprot id: A0A068NM60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

59505:FB03 RS03950
gene id: 59505:FB03_RS03950
uniprot id: A0A068NG66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

59505:FB03 RS02175
gene id: 59505:FB03_RS02175
uniprot id: A0A068NFP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

59505:FB03 RS02240
gene id: 59505:FB03_RS02240
uniprot id: A0A068NF76
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS06895
gene id: 59505:FB03_RS06895
uniprot id: A0A068NK16
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

59505:FB03 RS07845
gene id: 59505:FB03_RS07845
uniprot id: A0A068NHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

59505:FB03 RS05010
gene id: 59505:FB03_RS05010
uniprot id: A0A068NGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS00115
gene id: 59505:FB03_RS00115
uniprot id: A0A068NEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS04915
gene id: 59505:FB03_RS04915
uniprot id: A0A068NGS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS03730
gene id: 59505:FB03_RS03730
uniprot id: A0A068NIJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

59505:FB03 RS03895
gene id: 59505:FB03_RS03895
uniprot id: A0A068NGM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

59505:FB03 RS03755
gene id: 59505:FB03_RS03755
uniprot id: A0A068NIL9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

59505:FB03 RS02555
gene id: 59505:FB03_RS02555
uniprot id: A0A068NFD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

59505:FB03 RS06835
gene id: 59505:FB03_RS06835
uniprot id: A0A068NHG0
names: Similarity
messages: Belongs to the HIBADH-related family.

59505:FB03 RS02465
gene id: 59505:FB03_RS02465
uniprot id: A0A068NLH0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

59505:FB03 RS02755
gene id: 59505:FB03_RS02755
uniprot id: A0A068NHZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

59505:FB03 RS02630
gene id: 59505:FB03_RS02630
uniprot id: A0A068NHX9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

59505:FB03 RS03800
gene id: 59505:FB03_RS03800
uniprot id: A0A068NM53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

59505:FB03 RS04280
gene id: 59505:FB03_RS04280
uniprot id: A0A068NGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

59505:FB03 RS02390
gene id: 59505:FB03_RS02390
uniprot id: A0A068NLF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

59505:FB03 RS04850
gene id: 59505:FB03_RS04850
uniprot id: A0A068NGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

59505:FB03 RS02595
gene id: 59505:FB03_RS02595
uniprot id: A0A068NHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

59505:FB03 RS07830
gene id: 59505:FB03_RS07830
uniprot id: A0A068NKA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

59505:FB03 RS00890
gene id: 59505:FB03_RS00890
uniprot id: A0A068NF71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

59505:FB03 RS06710
gene id: 59505:FB03_RS06710
uniprot id: A0A068NNA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

59505:FB03 RS03750
gene id: 59505:FB03_RS03750
uniprot id: A0A068NM40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

59505:FB03 RS05630
gene id: 59505:FB03_RS05630
uniprot id: A0A068NH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS03435
gene id: 59505:FB03_RS03435
uniprot id: A0A068NGB0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

59505:FB03 RS03450
gene id: 59505:FB03_RS03450
uniprot id: A0A068NLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS07860
gene id: 59505:FB03_RS07860
uniprot id: A0A068NI44
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

59505:FB03 RS06055
gene id: 59505:FB03_RS06055
uniprot id: A0A068NH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS03840
gene id: 59505:FB03_RS03840
uniprot id: A0A068NGL3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

59505:FB03 RS02605
gene id: 59505:FB03_RS02605
uniprot id: A0A068NFQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

59505:FB03 RS04575
gene id: 59505:FB03_RS04575
uniprot id: A0A068NGV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

59505:FB03 RS05655
gene id: 59505:FB03_RS05655
uniprot id: A0A068NH97
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

59505:FB03 RS03980
gene id: 59505:FB03_RS03980
uniprot id: A0A068NGN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

59505:FB03 RS03680
gene id: 59505:FB03_RS03680
uniprot id: A0A068NGF4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS00590
gene id: 59505:FB03_RS00590
uniprot id: A0A068NEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

59505:FB03 RS02145
gene id: 59505:FB03_RS02145
uniprot id: A0A068NFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

59505:FB03 RS05030
gene id: 59505:FB03_RS05030
uniprot id: A0A068NMJ9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

59505:FB03 RS06460
gene id: 59505:FB03_RS06460
uniprot id: A0A068NHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

59505:FB03 RS07690
gene id: 59505:FB03_RS07690
uniprot id: A0A068NI24
names: Similarity
messages: Belongs to the WXG100 family.

59505:FB03 RS03885
gene id: 59505:FB03_RS03885
uniprot id: A0A068NIP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

59505:FB03 RS03120
gene id: 59505:FB03_RS03120
uniprot id: A0A068NG53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

59505:FB03 RS09315
gene id: 59505:FB03_RS09315
uniprot id: A0A068NHL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

59505:FB03 RS01295
gene id: 59505:FB03_RS01295
uniprot id: A0A068NL11
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

59505:FB03 RS04320
gene id: 59505:FB03_RS04320
uniprot id: A0A068NIV3
names: Similarity
messages: Belongs to the peptidase M18 family.

59505:FB03 RS05380
gene id: 59505:FB03_RS05380
uniprot id: A0A068NH57
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

59505:FB03 RS08815
gene id: 59505:FB03_RS08815
uniprot id: A0A068NIP0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS00640
gene id: 59505:FB03_RS00640
uniprot id: A0A068NF10
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS01010
gene id: 59505:FB03_RS01010
uniprot id: A0A068NHB1
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS07550
gene id: 59505:FB03_RS07550
uniprot id: A0A068NI07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS02255
gene id: 59505:FB03_RS02255
uniprot id: A0A068NHS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

59505:FB03 RS03855
gene id: 59505:FB03_RS03855
uniprot id: A0A068NIP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

59505:FB03 RS08595
gene id: 59505:FB03_RS08595
uniprot id: A0A068NP07
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

59505:FB03 RS03780
gene id: 59505:FB03_RS03780
uniprot id: A0A068NIN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

59505:FB03 RS08270
gene id: 59505:FB03_RS08270
uniprot id: A0A068NIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

59505:FB03 RS03630
gene id: 59505:FB03_RS03630
uniprot id: A0A068NG81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

59505:FB03 RS06250
gene id: 59505:FB03_RS06250
uniprot id: A0A068NH42
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

59505:FB03 RS00540
gene id: 59505:FB03_RS00540
uniprot id: A0A068NET0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

59505:FB03 RS01015
gene id: 59505:FB03_RS01015
uniprot id: A0A068NF24
names: Similarity
messages: Belongs to the FemABX family.

59505:FB03 RS08100
gene id: 59505:FB03_RS08100
uniprot id: A0A068NI72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

59505:FB03 RS03685
gene id: 59505:FB03_RS03685
uniprot id: A0A068NFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

59505:FB03 RS07230
gene id: 59505:FB03_RS07230
uniprot id: A0A068NK49
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS01625
gene id: 59505:FB03_RS01625
uniprot id: A0A068NEY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS06380
gene id: 59505:FB03_RS06380
uniprot id: A0A068NHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

59505:FB03 RS00225
gene id: 59505:FB03_RS00225
uniprot id: A0A068NET1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

59505:FB03 RS08810
gene id: 59505:FB03_RS08810
uniprot id: A0A068NII7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

59505:FB03 RS04595
gene id: 59505:FB03_RS04595
uniprot id: A0A068NME1
names: Similarity
messages: Belongs to the carbamate kinase family.

59505:FB03 RS03060
gene id: 59505:FB03_RS03060
uniprot id: A0A068NFM6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

59505:FB03 RS07570
gene id: 59505:FB03_RS07570
uniprot id: A0A068NK78
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

59505:FB03 RS08650
gene id: 59505:FB03_RS08650
uniprot id: A0A068NIG3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

59505:FB03 RS06430
gene id: 59505:FB03_RS06430
uniprot id: A0A068NHN3
names: Similarity
messages: Belongs to the ParB family.

59505:FB03 RS01990
gene id: 59505:FB03_RS01990
uniprot id: A0A068NF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

59505:FB03 RS08185
gene id: 59505:FB03_RS08185
uniprot id: A0A068NHY5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59505:FB03 RS00785
gene id: 59505:FB03_RS00785
uniprot id: A0A068NF60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

59505:FB03 RS03875
gene id: 59505:FB03_RS03875
uniprot id: A0A068NM64
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59505:FB03 RS04125
gene id: 59505:FB03_RS04125
uniprot id: A0A068NIS8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

59505:FB03 RS02425
gene id: 59505:FB03_RS02425
uniprot id: A0A068NFM3
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS00290
gene id: 59505:FB03_RS00290
uniprot id: A0A068NEC7
names: Similarity
messages: Belongs to the IMPACT family.

59505:FB03 RS02330
gene id: 59505:FB03_RS02330
uniprot id: A0A068NF91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

59505:FB03 RS00035
gene id: 59505:FB03_RS00035
uniprot id: A0A068NKH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

59505:FB03 RS06630
gene id: 59505:FB03_RS06630
uniprot id: A0A068NJU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS01520
gene id: 59505:FB03_RS01520
uniprot id: A0A068NHH2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS03710
gene id: 59505:FB03_RS03710
uniprot id: A0A068NGG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS07120
gene id: 59505:FB03_RS07120
uniprot id: A0A068NHW1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

59505:FB03 RS03860
gene id: 59505:FB03_RS03860
uniprot id: A0A068NGE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

59505:FB03 RS08555
gene id: 59505:FB03_RS08555
uniprot id: A0A068NIE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

59505:FB03 RS00340
gene id: 59505:FB03_RS00340
uniprot id: A0A068NGX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

59505:FB03 RS02035
gene id: 59505:FB03_RS02035
uniprot id: A0A068NFL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS04065
gene id: 59505:FB03_RS04065
uniprot id: A0A068NIS0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

59505:FB03 RS03775
gene id: 59505:FB03_RS03775
uniprot id: A0A068NM51
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

59505:FB03 RS03825
gene id: 59505:FB03_RS03825
uniprot id: A0A068NM56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

59505:FB03 RS07070
gene id: 59505:FB03_RS07070
uniprot id: A0A068NHV2
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS00490
gene id: 59505:FB03_RS00490
uniprot id: A0A068NEG0
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS02620
gene id: 59505:FB03_RS02620
uniprot id: A0A068NFE1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

59505:FB03 RS04430
gene id: 59505:FB03_RS04430
uniprot id: A0A068NMC4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

59505:FB03 RS08025
gene id: 59505:FB03_RS08025
uniprot id: A0A068NKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

59505:FB03 RS05725
gene id: 59505:FB03_RS05725
uniprot id: A0A068NHA7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

59505:FB03 RS00580
gene id: 59505:FB03_RS00580
uniprot id: A0A068NEZ6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

59505:FB03 RS05625
gene id: 59505:FB03_RS05625
uniprot id: A0A068NH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS02080
gene id: 59505:FB03_RS02080
uniprot id: A0A068NHP7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

59505:FB03 RS07575
gene id: 59505:FB03_RS07575
uniprot id: A0A068NI11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

59505:FB03 RS08745
gene id: 59505:FB03_RS08745
uniprot id: A0A068NI80
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

59505:FB03 RS06360
gene id: 59505:FB03_RS06360
uniprot id: A0A068NN40
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

59505:FB03 RS01255
gene id: 59505:FB03_RS01255
uniprot id: A0A068NF50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

59505:FB03 RS04710
gene id: 59505:FB03_RS04710
uniprot id: A0A068NMF7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

59505:FB03 RS01485
gene id: 59505:FB03_RS01485
uniprot id: A0A068NEX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

59505:FB03 RS00565
gene id: 59505:FB03_RS00565
uniprot id: A0A068NKR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

59505:FB03 RS02230
gene id: 59505:FB03_RS02230
uniprot id: A0A068NFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

59505:FB03 RS02855
gene id: 59505:FB03_RS02855
uniprot id: A0A068NI21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

59505:FB03 RS02025
gene id: 59505:FB03_RS02025
uniprot id: A0A068NHP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

59505:FB03 RS06570
gene id: 59505:FB03_RS06570
uniprot id: A0A068NHI6
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS04015
gene id: 59505:FB03_RS04015
uniprot id: A0A068NGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

59505:FB03 RS08805
gene id: 59505:FB03_RS08805
uniprot id: A0A068NKM2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

59505:FB03 RS03020
gene id: 59505:FB03_RS03020
uniprot id: A0A068NG34
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

59505:FB03 RS00015
gene id: 59505:FB03_RS00015
uniprot id: A0A068NEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

59505:FB03 RS02490
gene id: 59505:FB03_RS02490
uniprot id: A0A068NLH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

59505:FB03 RS02070
gene id: 59505:FB03_RS02070
uniprot id: A0A068NLB0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

59505:FB03 RS01585
gene id: 59505:FB03_RS01585
uniprot id: A0A068NHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

59505:FB03 RS02950
gene id: 59505:FB03_RS02950
uniprot id: A0A068NLP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS00715
gene id: 59505:FB03_RS00715
uniprot id: A0A068NH67
names: Similarity
messages: Belongs to the ribF family.

59505:FB03 RS02385
gene id: 59505:FB03_RS02385
uniprot id: A0A068NFA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

59505:FB03 RS02430
gene id: 59505:FB03_RS02430
uniprot id: A0A068NFS8
names: Similarity
messages: Belongs to the DEAD box helicase family.

59505:FB03 RS03815
gene id: 59505:FB03_RS03815
uniprot id: A0A068NGL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

59505:FB03 RS00135
gene id: 59505:FB03_RS00135
uniprot id: A0A068NEK1
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

59505:FB03 RS03600
gene id: 59505:FB03_RS03600
uniprot id: A0A068NIG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

59505:FB03 RS01610
gene id: 59505:FB03_RS01610
uniprot id: A0A068NHI3
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

59505:FB03 RS07565
gene id: 59505:FB03_RS07565
uniprot id: A0A068NNM7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

59505:FB03 RS06985
gene id: 59505:FB03_RS06985
uniprot id: A0A068NNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS05545
gene id: 59505:FB03_RS05545
uniprot id: A0A068NMS0
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

59505:FB03 RS02815
gene id: 59505:FB03_RS02815
uniprot id: A0A068NG02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

59505:FB03 RS06450
gene id: 59505:FB03_RS06450
uniprot id: A0A068NHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

59505:FB03 RS01995
gene id: 59505:FB03_RS01995
uniprot id: A0A068NL99
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

59505:FB03 RS08720
gene id: 59505:FB03_RS08720
uniprot id: A0A068NI74
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

59505:FB03 RS04100
gene id: 59505:FB03_RS04100
uniprot id: A0A068NGP2
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS06535
gene id: 59505:FB03_RS06535
uniprot id: A0A068NN71
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

59505:FB03 RS01800
gene id: 59505:FB03_RS01800
uniprot id: A0A068NL74
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS04515
gene id: 59505:FB03_RS04515
uniprot id: A0A068NMD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

59505:FB03 RS01690
gene id: 59505:FB03_RS01690
uniprot id: A0A068NFG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS01555
gene id: 59505:FB03_RS01555
uniprot id: A0A068NHH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

59505:FB03 RS03615
gene id: 59505:FB03_RS03615
uniprot id: A0A068NFY4
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS05735
gene id: 59505:FB03_RS05735
uniprot id: A0A068NGU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

59505:FB03 RS05645
gene id: 59505:FB03_RS05645
uniprot id: A0A068NJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS00480
gene id: 59505:FB03_RS00480
uniprot id: A0A068NER7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59505:FB03 RS00605
gene id: 59505:FB03_RS00605
uniprot id: A0A068NH21
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS00945
gene id: 59505:FB03_RS00945
uniprot id: A0A068NF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

59505:FB03 RS05230
gene id: 59505:FB03_RS05230
uniprot id: A0A068NGL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

59505:FB03 RS00555
gene id: 59505:FB03_RS00555
uniprot id: A0A068NEH1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

59505:FB03 RS04410
gene id: 59505:FB03_RS04410
uniprot id: A0A068NGK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS02575
gene id: 59505:FB03_RS02575
uniprot id: A0A068NFP8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

59505:FB03 RS02015
gene id: 59505:FB03_RS02015
uniprot id: A0A068NF37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

59505:FB03 RS02395
gene id: 59505:FB03_RS02395
uniprot id: A0A068NHU0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

59505:FB03 RS06310
gene id: 59505:FB03_RS06310
uniprot id: A0A068NN30
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

59505:FB03 RS07470
gene id: 59505:FB03_RS07470
uniprot id: A0A068NK69
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

59505:FB03 RS05080
gene id: 59505:FB03_RS05080
uniprot id: A0A068NGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS04305
gene id: 59505:FB03_RS04305
uniprot id: A0A068NGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

59505:FB03 RS01870
gene id: 59505:FB03_RS01870
uniprot id: A0A068NL82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

59505:FB03 RS02450
gene id: 59505:FB03_RS02450
uniprot id: A0A068NFM8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

59505:FB03 RS05575
gene id: 59505:FB03_RS05575
uniprot id: A0A068NGR9
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS06620
gene id: 59505:FB03_RS06620
uniprot id: A0A068NHB2
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS03545
gene id: 59505:FB03_RS03545
uniprot id: A0A068NLZ1
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

59505:FB03 RS08570
gene id: 59505:FB03_RS08570
uniprot id: A0A068NP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

59505:FB03 RS08425
gene id: 59505:FB03_RS08425
uniprot id: A0A068NKG9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

59505:FB03 RS06355
gene id: 59505:FB03_RS06355
uniprot id: A0A068NH60
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS08455
gene id: 59505:FB03_RS08455
uniprot id: A0A068NKH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

59505:FB03 RS08620
gene id: 59505:FB03_RS08620
uniprot id: A0A068NI60
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

59505:FB03 RS01350
gene id: 59505:FB03_RS01350
uniprot id: A0A068NHF3
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

59505:FB03 RS02655
gene id: 59505:FB03_RS02655
uniprot id: A0A068NLJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS06990
gene id: 59505:FB03_RS06990
uniprot id: A0A068NK24
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

59505:FB03 RS04485
gene id: 59505:FB03_RS04485
uniprot id: A0A068NMD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

59505:FB03 RS06760
gene id: 59505:FB03_RS06760
uniprot id: A0A068NJW2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

59505:FB03 RS03425
gene id: 59505:FB03_RS03425
uniprot id: A0A068NID0
names: Similarity
messages: Belongs to the TrpC family.

59505:FB03 RS06280
gene id: 59505:FB03_RS06280
uniprot id: A0A068NH46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

59505:FB03 RS02930
gene id: 59505:FB03_RS02930
uniprot id: A0A068NI34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

59505:FB03 RS02020
gene id: 59505:FB03_RS02020
uniprot id: A0A068NLA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

59505:FB03 RS06800
gene id: 59505:FB03_RS06800
uniprot id: A0A068NHM9
names: Similarity
messages: Belongs to the DapA family.

59505:FB03 RS05515
gene id: 59505:FB03_RS05515
uniprot id: A0A068NMR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Cytoplasm
messages: Homotetramer.

59505:FB03 RS00620
gene id: 59505:FB03_RS00620
uniprot id: A0A068NEI4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

59505:FB03 RS00860
gene id: 59505:FB03_RS00860
uniprot id: A0A068NF06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

59505:FB03 RS08290
gene id: 59505:FB03_RS08290
uniprot id: A0A068NIA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane

59505:FB03 RS01630
gene id: 59505:FB03_RS01630
uniprot id: A0A068NL53
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS02375
gene id: 59505:FB03_RS02375
uniprot id: A0A068NFL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

59505:FB03 RS08380
gene id: 59505:FB03_RS08380
uniprot id: A0A068NII0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

59505:FB03 RS02310
gene id: 59505:FB03_RS02310
uniprot id: A0A068NHS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

59505:FB03 RS04330
gene id: 59505:FB03_RS04330
uniprot id: A0A068NGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

59505:FB03 RS07835
gene id: 59505:FB03_RS07835
uniprot id: A0A068NI41
names: Similarity
messages: Belongs to the peptidase S13 family.

59505:FB03 RS06255
gene id: 59505:FB03_RS06255
uniprot id: A0A068NN20
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

59505:FB03 RS00335
gene id: 59505:FB03_RS00335
uniprot id: A0A068NKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

59505:FB03 RS05685
gene id: 59505:FB03_RS05685
uniprot id: A0A068NMT6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

59505:FB03 RS01830
gene id: 59505:FB03_RS01830
uniprot id: A0A068NF12
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

59505:FB03 RS08795
gene id: 59505:FB03_RS08795
uniprot id: A0A068NI85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS00955
gene id: 59505:FB03_RS00955
uniprot id: A0A068NF77
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

59505:FB03 RS05945
gene id: 59505:FB03_RS05945
uniprot id: A0A068NHE5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59505:FB03 RS04130
gene id: 59505:FB03_RS04130
uniprot id: A0A068NGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS04450
gene id: 59505:FB03_RS04450
uniprot id: A0A068NGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

59505:FB03 RS08205
gene id: 59505:FB03_RS08205
uniprot id: A0A068NI87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

59505:FB03 RS08260
gene id: 59505:FB03_RS08260
uniprot id: A0A068NKE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

59505:FB03 RS08950
gene id: 59505:FB03_RS08950
uniprot id: A0A068NKP4
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

59505:FB03 RS00895
gene id: 59505:FB03_RS00895
uniprot id: A0A068NEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

59505:FB03 RS04630
gene id: 59505:FB03_RS04630
uniprot id: A0A068NIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

59505:FB03 RS03795
gene id: 59505:FB03_RS03795
uniprot id: A0A068NG42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

59505:FB03 RS02565
gene id: 59505:FB03_RS02565
uniprot id: A0A068NLI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

59505:FB03 RS01970
gene id: 59505:FB03_RS01970
uniprot id: A0A068NL94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

59505:FB03 RS08460
gene id: 59505:FB03_RS08460
uniprot id: A0A068NID1
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS07670
gene id: 59505:FB03_RS07670
uniprot id: A0A068NI79
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

59505:FB03 RS01120
gene id: 59505:FB03_RS01120
uniprot id: A0A068NES8
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS00980
gene id: 59505:FB03_RS00980
uniprot id: A0A068NF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

59505:FB03 RS02875
gene id: 59505:FB03_RS02875
uniprot id: A0A068NFJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

59505:FB03 RS05760
gene id: 59505:FB03_RS05760
uniprot id: A0A068NGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

59505:FB03 RS02380
gene id: 59505:FB03_RS02380
uniprot id: A0A068NFR9
names: Similarity
messages: Belongs to the peptidase A24 family.

59505:FB03 RS06890
gene id: 59505:FB03_RS06890
uniprot id: A0A068NNF0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

59505:FB03 RS03560
gene id: 59505:FB03_RS03560
uniprot id: A0A068NGC9
names: Similarity
messages: Belongs to the FemABX family.

59505:FB03 RS04335
gene id: 59505:FB03_RS04335
uniprot id: A0A068NGB2
names: Similarity
messages: Belongs to the peptidase S33 family.

59505:FB03 RS03540
gene id: 59505:FB03_RS03540
uniprot id: A0A068NFW5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

59505:FB03 RS01270
gene id: 59505:FB03_RS01270
uniprot id: A0A068NL07
names: Similarity
messages: Belongs to the glutamine synthetase family.

59505:FB03 RS04070
gene id: 59505:FB03_RS04070
uniprot id: A0A068NGH0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

59505:FB03 RS05130
gene id: 59505:FB03_RS05130
uniprot id: A0A068NGV4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

59505:FB03 RS05970
gene id: 59505:FB03_RS05970
uniprot id: A0A068NHF1
names: Similarity
messages: Belongs to the DapA family.

59505:FB03 RS04920
gene id: 59505:FB03_RS04920
uniprot id: A0A068NGZ4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

59505:FB03 RS01330
gene id: 59505:FB03_RS01330
uniprot id: A0A068NF62
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

59505:FB03 RS07045
gene id: 59505:FB03_RS07045
uniprot id: A0A068NHU8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

59505:FB03 RS02720
gene id: 59505:FB03_RS02720
uniprot id: A0A068NLK9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

59505:FB03 RS00235
gene id: 59505:FB03_RS00235
uniprot id: A0A068NKK6
names: Similarity
messages: Belongs to the peptidase M1 family.

59505:FB03 RS08545
gene id: 59505:FB03_RS08545
uniprot id: A0A068NNZ9
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

59505:FB03 RS01575
gene id: 59505:FB03_RS01575
uniprot id: A0A068NEY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

59505:FB03 RS00280
gene id: 59505:FB03_RS00280
uniprot id: A0A068NEU2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

59505:FB03 RS02305
gene id: 59505:FB03_RS02305
uniprot id: A0A068NLE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

59505:FB03 RS03830
gene id: 59505:FB03_RS03830
uniprot id: A0A068NIN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

59505:FB03 RS02980
gene id: 59505:FB03_RS02980
uniprot id: A0A068NLQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

59505:FB03 RS02370
gene id: 59505:FB03_RS02370
uniprot id: A0A068NHT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

59505:FB03 RS05345
gene id: 59505:FB03_RS05345
uniprot id: A0A068NJ70
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
messages: Reaction proceeds via a syn dehydration.

59505:FB03 RS08740
gene id: 59505:FB03_RS08740
uniprot id: A0A068NIN0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

59505:FB03 RS08275
gene id: 59505:FB03_RS08275
uniprot id: A0A068NI00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

59505:FB03 RS07885
gene id: 59505:FB03_RS07885
uniprot id: A0A068NNR0
names: Similarity
messages: Belongs to the ketopantoate reductase family.

59505:FB03 RS00645
gene id: 59505:FB03_RS00645
uniprot id: A0A068NEJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

59505:FB03 RS02770
gene id: 59505:FB03_RS02770
uniprot id: A0A068NFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

59505:FB03 RS02545
gene id: 59505:FB03_RS02545
uniprot id: A0A068NFP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

59505:FB03 RS02045
gene id: 59505:FB03_RS02045
uniprot id: A0A068NLA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

59505:FB03 RS04375
gene id: 59505:FB03_RS04375
uniprot id: A0A068NGK1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

59505:FB03 RS02040
gene id: 59505:FB03_RS02040
uniprot id: A0A068NF42
names: Similarity
messages: Belongs to the transketolase family.

59505:FB03 RS03675
gene id: 59505:FB03_RS03675
uniprot id: A0A068NG90
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

59505:FB03 RS05445
gene id: 59505:FB03_RS05445
uniprot id: A0A068NH64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

59505:FB03 RS04600
gene id: 59505:FB03_RS04600
uniprot id: A0A068NIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

59505:FB03 RS03760
gene id: 59505:FB03_RS03760
uniprot id: A0A068NGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

59505:FB03 RS03335
gene id: 59505:FB03_RS03335
uniprot id: A0A068NG27
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

59505:FB03 RS02530
gene id: 59505:FB03_RS02530
uniprot id: A0A068NLH9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

59505:FB03 RS00725
gene id: 59505:FB03_RS00725
uniprot id: A0A068NF53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

59505:FB03 RS02190
gene id: 59505:FB03_RS02190
uniprot id: A0A068NLC4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

59505:FB03 RS07980
gene id: 59505:FB03_RS07980
uniprot id: A0A068NI55
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS07840
gene id: 59505:FB03_RS07840
uniprot id: A0A068NI99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

59505:FB03 RS03740
gene id: 59505:FB03_RS03740
uniprot id: A0A068NGI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

59505:FB03 RS03690
gene id: 59505:FB03_RS03690
uniprot id: A0A068NM16
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

59505:FB03 RS02315
gene id: 59505:FB03_RS02315
uniprot id: A0A068NFK3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

59505:FB03 RS06345
gene id: 59505:FB03_RS06345
uniprot id: A0A068NHE4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

59505:FB03 RS04080
gene id: 59505:FB03_RS04080
uniprot id: A0A068NG80
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

59505:FB03 RS10200
gene id: 59505:FB03_RS10200
uniprot id: A0A068NGD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

59505:FB03 RS08395
gene id: 59505:FB03_RS08395
uniprot id: A0A068NNX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

59505:FB03 RS01875
gene id: 59505:FB03_RS01875
uniprot id: A0A068NHL9
names: Subunit
messages: Monomer.

59505:FB03 RS02365
gene id: 59505:FB03_RS02365
uniprot id: A0A068NLF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

59505:FB03 RS01515
gene id: 59505:FB03_RS01515
uniprot id: A0A068NL38
names: Similarity
messages: Belongs to the Dps family.

59505:FB03 RS00535
gene id: 59505:FB03_RS00535
uniprot id: A0A068NH09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

59505:FB03 RS00060
gene id: 59505:FB03_RS00060
uniprot id: A0A068NE89
names: Subcellular Location Annotation
messages: Membrane

59505:FB03 RS01820
gene id: 59505:FB03_RS01820
uniprot id: A0A068NFI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59505:FB03 RS02745
gene id: 59505:FB03_RS02745
uniprot id: A0A068NFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

59505:FB03 RS00405
gene id: 59505:FB03_RS00405
uniprot id: A0A068NEW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

59505:FB03 RS07085
gene id: 59505:FB03_RS07085
uniprot id: A0A068NNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

59505:FB03 RS03810
gene id: 59505:FB03_RS03810
uniprot id: A0A068NGE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

59505:FB03 RS00295
gene id: 59505:FB03_RS00295
uniprot id: A0A068NKL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

59505:FB03 RS03125
gene id: 59505:FB03_RS03125
uniprot id: A0A068NFN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

59505:FB03 RS05290
gene id: 59505:FB03_RS05290
uniprot id: A0A068NMN6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

59505:FB03 RS05605
gene id: 59505:FB03_RS05605
uniprot id: A0A068NMS7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

59505:FB03 RS01640
gene id: 59505:FB03_RS01640
uniprot id: A0A068NFA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

59505:FB03 RS02830
gene id: 59505:FB03_RS02830
uniprot id: A0A068NI15
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

59505:FB03 RS03570
gene id: 59505:FB03_RS03570
uniprot id: A0A068NLZ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

59505:FB03 RS03005
gene id: 59505:FB03_RS03005
uniprot id: A0A068NLQ9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

59505:FB03 RS08215
gene id: 59505:FB03_RS08215
uniprot id: A0A068NHZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

59505:FB03 RS01475
gene id: 59505:FB03_RS01475
uniprot id: A0A068NF83
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

59505:FB03 RS08725
gene id: 59505:FB03_RS08725
uniprot id: A0A068NP24
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.