594679:SD28 RS01630
gene id: 594679:SD28_RS01630
uniprot id: A0A0A8E8G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

594679:SD28 RS03530
gene id: 594679:SD28_RS03530
uniprot id: A0A0A8E444
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

594679:SD28 RS00215
gene id: 594679:SD28_RS00215
uniprot id: A0A0A8E1V7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

594679:SD28 RS06290
gene id: 594679:SD28_RS06290
uniprot id: A0A0A8E4U8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

594679:SD28 RS05110
gene id: 594679:SD28_RS05110
uniprot id: A0A0A8E526
names: Similarity
messages: Belongs to the YjdM family.

594679:SD28 RS05175
gene id: 594679:SD28_RS05175
uniprot id: A0A0A8E686
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

594679:SD28 RS00765
gene id: 594679:SD28_RS00765
uniprot id: A0A0A8E3U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

594679:SD28 RS03975
gene id: 594679:SD28_RS03975
uniprot id: A0A0A8E3N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS05495
gene id: 594679:SD28_RS05495
uniprot id: A0A0A8EAE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

594679:SD28 RS00770
gene id: 594679:SD28_RS00770
uniprot id: A0A0A8E2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

594679:SD28 RS03450
gene id: 594679:SD28_RS03450
uniprot id: A0A0A8E481
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

594679:SD28 RS04500
gene id: 594679:SD28_RS04500
uniprot id: L8BTB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

594679:SD28 RS06540
gene id: 594679:SD28_RS06540
uniprot id: A0A0A8E5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

594679:SD28 RS05485
gene id: 594679:SD28_RS05485
uniprot id: A0A0A8E5B6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

594679:SD28 RS02400
gene id: 594679:SD28_RS02400
uniprot id: A0A0A8E8Y8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

594679:SD28 RS00675
gene id: 594679:SD28_RS00675
uniprot id: A0A0A8E2U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS02420
gene id: 594679:SD28_RS02420
uniprot id: A0A0A8E329
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

594679:SD28 RS06345
gene id: 594679:SD28_RS06345
uniprot id: A0A0A8E5N3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

594679:SD28 RS06220
gene id: 594679:SD28_RS06220
uniprot id: A0A0A8E5H3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

594679:SD28 RS05200
gene id: 594679:SD28_RS05200
uniprot id: A0A0A8E692
names: Subcellular Location Annotation
messages: Cytoplasm

594679:SD28 RS06130
gene id: 594679:SD28_RS06130
uniprot id: A0A0A8E5G0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

594679:SD28 RS02890
gene id: 594679:SD28_RS02890
uniprot id: A0A0A8E375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS06165
gene id: 594679:SD28_RS06165
uniprot id: A0A0A8E6L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

594679:SD28 RS07150
gene id: 594679:SD28_RS07150
uniprot id: A0A0A8E728
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

594679:SD28 RS02300
gene id: 594679:SD28_RS02300
uniprot id: A0A0A8E4S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

594679:SD28 RS00425
gene id: 594679:SD28_RS00425
uniprot id: A0A0A8E1Z9
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS01635
gene id: 594679:SD28_RS01635
uniprot id: A0A0A8E4B1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

594679:SD28 RS07340
gene id: 594679:SD28_RS07340
uniprot id: A0A0A8E764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS00415
gene id: 594679:SD28_RS00415
uniprot id: A0A0A8E2L7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS01610
gene id: 594679:SD28_RS01610
uniprot id: A0A0A8E4A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

594679:SD28 RS03395
gene id: 594679:SD28_RS03395
uniprot id: A0A0A8E473
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

594679:SD28 RS02695
gene id: 594679:SD28_RS02695
uniprot id: A0A0A8E3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS01970
gene id: 594679:SD28_RS01970
uniprot id: A0A0A8E3H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS05390
gene id: 594679:SD28_RS05390
uniprot id: A0A0A8EAD5
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

594679:SD28 RS01295
gene id: 594679:SD28_RS01295
uniprot id: A0A0A8E339
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

594679:SD28 RS02395
gene id: 594679:SD28_RS02395
uniprot id: A0A0A8E326
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

594679:SD28 RS03480
gene id: 594679:SD28_RS03480
uniprot id: A0A0A8E3G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

594679:SD28 RS03195
gene id: 594679:SD28_RS03195
uniprot id: A0A0A8E540
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

594679:SD28 RS07185
gene id: 594679:SD28_RS07185
uniprot id: A0A0A8E608
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

594679:SD28 RS04985
gene id: 594679:SD28_RS04985
uniprot id: A0A0A8E4V6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

594679:SD28 RS02285
gene id: 594679:SD28_RS02285
uniprot id: A0A0A8E3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

594679:SD28 RS06375
gene id: 594679:SD28_RS06375
uniprot id: A0A0A8E4W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

594679:SD28 RS05395
gene id: 594679:SD28_RS05395
uniprot id: A0A0A8E6B8
names: Similarity
messages: Belongs to the peptidase M17 family.

594679:SD28 RS02175
gene id: 594679:SD28_RS02175
uniprot id: A0A0A8E3M2
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS03345
gene id: 594679:SD28_RS03345
uniprot id: A0A0A8E560
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

594679:SD28 RS05475
gene id: 594679:SD28_RS05475
uniprot id: A0A0A8E6C7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS01770
gene id: 594679:SD28_RS01770
uniprot id: A0A0A8E3D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

594679:SD28 RS03680
gene id: 594679:SD28_RS03680
uniprot id: A0A0A8E9E2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS03825
gene id: 594679:SD28_RS03825
uniprot id: A0A0A8E9G6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

594679:SD28 RS06200
gene id: 594679:SD28_RS06200
uniprot id: A0A0A8E5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

594679:SD28 RS02345
gene id: 594679:SD28_RS02345
uniprot id: A0A0A8E320
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

594679:SD28 RS07650
gene id: 594679:SD28_RS07650
uniprot id: A0A0A8EBG6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

594679:SD28 RS06270
gene id: 594679:SD28_RS06270
uniprot id: A0A0A8EAQ7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

594679:SD28 RS00420
gene id: 594679:SD28_RS00420
uniprot id: A0A0A8E2Q7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

594679:SD28 RS00540
gene id: 594679:SD28_RS00540
uniprot id: A0A0A8E7W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

594679:SD28 RS07615
gene id: 594679:SD28_RS07615
uniprot id: A0A0A8E5J3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

594679:SD28 RS02410
gene id: 594679:SD28_RS02410
uniprot id: A0A0A8E3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

594679:SD28 RS07225
gene id: 594679:SD28_RS07225
uniprot id: A0A0A8EB76
names: Subcellular Location Annotation
messages: Cytoplasm

594679:SD28 RS02830
gene id: 594679:SD28_RS02830
uniprot id: A0A0A8E369
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

594679:SD28 RS01065
gene id: 594679:SD28_RS01065
uniprot id: L8BTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

594679:SD28 RS02020
gene id: 594679:SD28_RS02020
uniprot id: A0A0A8E3J2
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05640
gene id: 594679:SD28_RS05640
uniprot id: A0A0A8EAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

594679:SD28 RS05075
gene id: 594679:SD28_RS05075
uniprot id: A0A0A8E637
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

594679:SD28 RS01430
gene id: 594679:SD28_RS01430
uniprot id: A0A0A8E8D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

594679:SD28 RS02580
gene id: 594679:SD28_RS02580
uniprot id: A0A0A8E3R4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

594679:SD28 RS05345
gene id: 594679:SD28_RS05345
uniprot id: A0A0A8E549
names: Similarity
messages: Belongs to the thioredoxin family.

594679:SD28 RS01985
gene id: 594679:SD28_RS01985
uniprot id: A0A0A8E4H9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

594679:SD28 RS04065
gene id: 594679:SD28_RS04065
uniprot id: A0A0A8E3P8
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS03005
gene id: 594679:SD28_RS03005
uniprot id: A0A0A8E956
names: Similarity
messages: Belongs to the SufE family.

594679:SD28 RS05960
gene id: 594679:SD28_RS05960
uniprot id: A0A0A8E5D2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

594679:SD28 RS03285
gene id: 594679:SD28_RS03285
uniprot id: A0A0A8E409
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

594679:SD28 RS01255
gene id: 594679:SD28_RS01255
uniprot id: A0A0A8E8A0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

594679:SD28 RS00030
gene id: 594679:SD28_RS00030
uniprot id: A0A0A8EBI0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

594679:SD28 RS04885
gene id: 594679:SD28_RS04885
uniprot id: A0A0A8E483
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

594679:SD28 RS01750
gene id: 594679:SD28_RS01750
uniprot id: A0A0A8E2N7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

594679:SD28 RS04615
gene id: 594679:SD28_RS04615
uniprot id: A0A0A8E423
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

594679:SD28 RS00310
gene id: 594679:SD28_RS00310
uniprot id: A0A0A8EBI5
names: Similarity
messages: Belongs to the YfgM family.

594679:SD28 RS02650
gene id: 594679:SD28_RS02650
uniprot id: A0A0A8E913
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

594679:SD28 RS02490
gene id: 594679:SD28_RS02490
uniprot id: A0A0A8E3V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

594679:SD28 RS05825
gene id: 594679:SD28_RS05825
uniprot id: A0A0A8E5G1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

594679:SD28 RS01810
gene id: 594679:SD28_RS01810
uniprot id: A0A0A8E8K7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS02860
gene id: 594679:SD28_RS02860
uniprot id: A0A0A8E402
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

594679:SD28 RS05080
gene id: 594679:SD28_RS05080
uniprot id: A0A0A8E4X5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

594679:SD28 RS03590
gene id: 594679:SD28_RS03590
uniprot id: A0A0A8E3H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

594679:SD28 RS02565
gene id: 594679:SD28_RS02565
uniprot id: A0A0A8E904
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

594679:SD28 RS06025
gene id: 594679:SD28_RS06025
uniprot id: A0A0A8E4R0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

594679:SD28 RS05580
gene id: 594679:SD28_RS05580
uniprot id: A0A0A8EAF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

594679:SD28 RS02530
gene id: 594679:SD28_RS02530
uniprot id: A0A0A8E4W6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

594679:SD28 RS04920
gene id: 594679:SD28_RS04920
uniprot id: A0A0A8E5Z9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

594679:SD28 RS00975
gene id: 594679:SD28_RS00975
uniprot id: A0A0A8E2V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

594679:SD28 RS06110
gene id: 594679:SD28_RS06110
uniprot id: A0A0A8E4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

594679:SD28 RS06640
gene id: 594679:SD28_RS06640
uniprot id: A0A0A8E6U4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS05900
gene id: 594679:SD28_RS05900
uniprot id: A0A0A8E6H9
names: Similarity
messages: Belongs to the RutC family.

594679:SD28 RS04635
gene id: 594679:SD28_RS04635
uniprot id: A0A0A8E4S7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05040
gene id: 594679:SD28_RS05040
uniprot id: A0A0A8EA52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS03835
gene id: 594679:SD28_RS03835
uniprot id: A0A0A8E487
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

594679:SD28 RS03155
gene id: 594679:SD28_RS03155
uniprot id: A0A0A8E440
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

594679:SD28 RS05115
gene id: 594679:SD28_RS05115
uniprot id: A0A0A8E4D1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

594679:SD28 RS07475
gene id: 594679:SD28_RS07475
uniprot id: A0A0A8EBD2
names: Similarity
messages: Belongs to the thioredoxin family.

594679:SD28 RS07205
gene id: 594679:SD28_RS07205
uniprot id: A0A0A8E738
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

594679:SD28 RS04715
gene id: 594679:SD28_RS04715
uniprot id: A0A0A8E449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS00145
gene id: 594679:SD28_RS00145
uniprot id: A0A0A8E2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

594679:SD28 RS06000
gene id: 594679:SD28_RS06000
uniprot id: A0A0A8E4Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

594679:SD28 RS01980
gene id: 594679:SD28_RS01980
uniprot id: A0A0A8E8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS04475
gene id: 594679:SD28_RS04475
uniprot id: A0A0A8E4I8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

594679:SD28 RS00690
gene id: 594679:SD28_RS00690
uniprot id: A0A0A8E3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

594679:SD28 RS00410
gene id: 594679:SD28_RS00410
uniprot id: A0A0A8E3N5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

594679:SD28 RS00710
gene id: 594679:SD28_RS00710
uniprot id: A0A0A8E7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

594679:SD28 RS01720
gene id: 594679:SD28_RS01720
uniprot id: A0A0A8E3C0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

594679:SD28 RS02660
gene id: 594679:SD28_RS02660
uniprot id: A0A0A8E4Y0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

594679:SD28 RS06910
gene id: 594679:SD28_RS06910
uniprot id: A0A0A8E5S8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

594679:SD28 RS06445
gene id: 594679:SD28_RS06445
uniprot id: A0A0A8EAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

594679:SD28 RS05615
gene id: 594679:SD28_RS05615
uniprot id: A0A0A8E6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

594679:SD28 RS02375
gene id: 594679:SD28_RS02375
uniprot id: A0A0A8E8Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

594679:SD28 RS06760
gene id: 594679:SD28_RS06760
uniprot id: A0A0A8E523
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

594679:SD28 RS00205
gene id: 594679:SD28_RS00205
uniprot id: A0A0A8E2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

594679:SD28 RS00865
gene id: 594679:SD28_RS00865
uniprot id: L8BSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS04800
gene id: 594679:SD28_RS04800
uniprot id: A0A0A8E5X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

594679:SD28 RS00025
gene id: 594679:SD28_RS00025
uniprot id: A0A0A8E3I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

594679:SD28 RS05145
gene id: 594679:SD28_RS05145
uniprot id: A0A0A8EA92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

594679:SD28 RS01675
gene id: 594679:SD28_RS01675
uniprot id: A0A0A8E2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

594679:SD28 RS06630
gene id: 594679:SD28_RS06630
uniprot id: A0A0A8EAW1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

594679:SD28 RS00905
gene id: 594679:SD28_RS00905
uniprot id: A0A0A8E3X8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS05065
gene id: 594679:SD28_RS05065
uniprot id: A0A0A8E4B9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

594679:SD28 RS07565
gene id: 594679:SD28_RS07565
uniprot id: A0A0A8EBE9
names: Similarity
messages: Belongs to the bacterial glucokinase family.

594679:SD28 RS01865
gene id: 594679:SD28_RS01865
uniprot id: A0A0A8E8M0
names: Similarity
messages: Belongs to the IucA/IucC family.

594679:SD28 RS04235
gene id: 594679:SD28_RS04235
uniprot id: A0A0A8E4J2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

594679:SD28 RS05140
gene id: 594679:SD28_RS05140
uniprot id: A0A0A8E4E9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

594679:SD28 RS06075
gene id: 594679:SD28_RS06075
uniprot id: A0A0A8E4R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS05710
gene id: 594679:SD28_RS05710
uniprot id: A0A0A8E595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

594679:SD28 RS00695
gene id: 594679:SD28_RS00695
uniprot id: A0A0A8E2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

594679:SD28 RS05895
gene id: 594679:SD28_RS05895
uniprot id: A0A0A8EAK1
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS06340
gene id: 594679:SD28_RS06340
uniprot id: A0A0A8E5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

594679:SD28 RS05295
gene id: 594679:SD28_RS05295
uniprot id: A0A0A8E4H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

594679:SD28 RS03400
gene id: 594679:SD28_RS03400
uniprot id: A0A0A8E3E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

594679:SD28 RS00430
gene id: 594679:SD28_RS00430
uniprot id: A0A0A8E7V4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

594679:SD28 RS02835
gene id: 594679:SD28_RS02835
uniprot id: A0A0A8E932
names: Similarity
messages: Belongs to the UPF0246 family.

594679:SD28 RS02330
gene id: 594679:SD28_RS02330
uniprot id: A0A0A8E4T3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

594679:SD28 RS07700
gene id: 594679:SD28_RS07700
uniprot id: A0A0A8EBH5
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05745
gene id: 594679:SD28_RS05745
uniprot id: A0A0A8E5F0
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04075
gene id: 594679:SD28_RS04075
uniprot id: A0A0A8E5I5
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS00160
gene id: 594679:SD28_RS00160
uniprot id: A0A0A8E1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS03475
gene id: 594679:SD28_RS03475
uniprot id: A0A0A8E485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

594679:SD28 RS03460
gene id: 594679:SD28_RS03460
uniprot id: A0A0A8E9B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

594679:SD28 RS05315
gene id: 594679:SD28_RS05315
uniprot id: A0A0A8E6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

594679:SD28 RS07045
gene id: 594679:SD28_RS07045
uniprot id: A0A0A8E5U4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

594679:SD28 RS02200
gene id: 594679:SD28_RS02200
uniprot id: A0A0A8E3M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

594679:SD28 RS01590
gene id: 594679:SD28_RS01590
uniprot id: A0A0A8E338
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

594679:SD28 RS04505
gene id: 594679:SD28_RS04505
uniprot id: A0A0A8E4Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS04700
gene id: 594679:SD28_RS04700
uniprot id: A0A0A8E5V5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

594679:SD28 RS01875
gene id: 594679:SD28_RS01875
uniprot id: A0A0A8E4F7
names: Similarity
messages: Belongs to the IucA/IucC family.

594679:SD28 RS03500
gene id: 594679:SD28_RS03500
uniprot id: A0A0A8E583
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

594679:SD28 RS03715
gene id: 594679:SD28_RS03715
uniprot id: A0A0A8E5B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

594679:SD28 RS06380
gene id: 594679:SD28_RS06380
uniprot id: A0A0A8EAS3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

594679:SD28 RS04250
gene id: 594679:SD28_RS04250
uniprot id: A0A0A8E9Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

594679:SD28 RS01940
gene id: 594679:SD28_RS01940
uniprot id: A0A0A8E3H3
names: Similarity
messages: Belongs to the YoeB family.

594679:SD28 RS00035
gene id: 594679:SD28_RS00035
uniprot id: A0A0A8E2F8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

594679:SD28 RS07230
gene id: 594679:SD28_RS07230
uniprot id: A0A0A8E743
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

594679:SD28 RS00600
gene id: 594679:SD28_RS00600
uniprot id: A0A0A8E3R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

594679:SD28 RS03645
gene id: 594679:SD28_RS03645
uniprot id: A0A0A8E4A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

594679:SD28 RS01025
gene id: 594679:SD28_RS01025
uniprot id: A0A0A8E403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

594679:SD28 RS00720
gene id: 594679:SD28_RS00720
uniprot id: A0A0A8E2R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

594679:SD28 RS04195
gene id: 594679:SD28_RS04195
uniprot id: A0A0A8E9N9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

594679:SD28 RS04575
gene id: 594679:SD28_RS04575
uniprot id: A0A0A8E5S9
names: Similarity
messages: Belongs to the UPF0434 family.

594679:SD28 RS03535
gene id: 594679:SD28_RS03535
uniprot id: A0A0A8E492
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

594679:SD28 RS00365
gene id: 594679:SD28_RS00365
uniprot id: A0A0A8E2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

594679:SD28 RS00315
gene id: 594679:SD28_RS00315
uniprot id: A0A0A8E2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

594679:SD28 RS05185
gene id: 594679:SD28_RS05185
uniprot id: A0A0A8E576
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

594679:SD28 RS03350
gene id: 594679:SD28_RS03350
uniprot id: A0A0A8E417
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

594679:SD28 RS00715
gene id: 594679:SD28_RS00715
uniprot id: A0A0A8E3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

594679:SD28 RS02260
gene id: 594679:SD28_RS02260
uniprot id: A0A0A8E3P2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS02975
gene id: 594679:SD28_RS02975
uniprot id: A0A0A8E516
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS02575
gene id: 594679:SD28_RS02575
uniprot id: A0A0A8E4X1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS02605
gene id: 594679:SD28_RS02605
uniprot id: A0A0A8E3R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

594679:SD28 RS07405
gene id: 594679:SD28_RS07405
uniprot id: A0A0A8E657
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

594679:SD28 RS04350
gene id: 594679:SD28_RS04350
uniprot id: A0A0A8E9S1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS06550
gene id: 594679:SD28_RS06550
uniprot id: A0A0A8E4Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

594679:SD28 RS04360
gene id: 594679:SD28_RS04360
uniprot id: A0A0A8E4G7
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

594679:SD28 RS04015
gene id: 594679:SD28_RS04015
uniprot id: A0A0A8E9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

594679:SD28 RS00830
gene id: 594679:SD28_RS00830
uniprot id: A0A0A8E2T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

594679:SD28 RS01730
gene id: 594679:SD28_RS01730
uniprot id: A0A0A8E8J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

594679:SD28 RS00730
gene id: 594679:SD28_RS00730
uniprot id: A0A0A8E251
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS02320
gene id: 594679:SD28_RS02320
uniprot id: A0A0A8E314
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

594679:SD28 RS06795
gene id: 594679:SD28_RS06795
uniprot id: A0A0A8EAY8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

594679:SD28 RS06045
gene id: 594679:SD28_RS06045
uniprot id: A0A0A8E5J2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

594679:SD28 RS06240
gene id: 594679:SD28_RS06240
uniprot id: A0A0A8E6M9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

594679:SD28 RS06115
gene id: 594679:SD28_RS06115
uniprot id: A0A0A8EAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

594679:SD28 RS00620
gene id: 594679:SD28_RS00620
uniprot id: A0A0A8E682
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

594679:SD28 RS00320
gene id: 594679:SD28_RS00320
uniprot id: A0A0A8E2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS03265
gene id: 594679:SD28_RS03265
uniprot id: A0A0A8E456
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

594679:SD28 RS00995
gene id: 594679:SD28_RS00995
uniprot id: A0A0A8E3Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

594679:SD28 RS05770
gene id: 594679:SD28_RS05770
uniprot id: A0A0A8E5F4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

594679:SD28 RS03405
gene id: 594679:SD28_RS03405
uniprot id: A0A0A8E9A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

594679:SD28 RS04665
gene id: 594679:SD28_RS04665
uniprot id: A0A0A8E438
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

594679:SD28 RS04855
gene id: 594679:SD28_RS04855
uniprot id: A0A0A8E478
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

594679:SD28 RS06265
gene id: 594679:SD28_RS06265
uniprot id: A0A0A8E4U5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS03515
gene id: 594679:SD28_RS03515
uniprot id: A0A0A8E3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

594679:SD28 RS07215
gene id: 594679:SD28_RS07215
uniprot id: A0A0A8E615
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

594679:SD28 RS02480
gene id: 594679:SD28_RS02480
uniprot id: A0A0A8E4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

594679:SD28 RS06480
gene id: 594679:SD28_RS06480
uniprot id: A0A0A8E6I0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

594679:SD28 RS05735
gene id: 594679:SD28_RS05735
uniprot id: A0A0A8E6F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

594679:SD28 RS06525
gene id: 594679:SD28_RS06525
uniprot id: A0A0A8E4Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

594679:SD28 RS00300
gene id: 594679:SD28_RS00300
uniprot id: A0A0A8E7T3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

594679:SD28 RS00325
gene id: 594679:SD28_RS00325
uniprot id: A0A0A8E1X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

594679:SD28 RS05995
gene id: 594679:SD28_RS05995
uniprot id: A0A0A8E7L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

594679:SD28 RS04795
gene id: 594679:SD28_RS04795
uniprot id: A0A0A8EA14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

594679:SD28 RS06085
gene id: 594679:SD28_RS06085
uniprot id: A0A0A8E6K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

594679:SD28 RS01315
gene id: 594679:SD28_RS01315
uniprot id: A0A0A8E304
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

594679:SD28 RS01775
gene id: 594679:SD28_RS01775
uniprot id: A0A0A8E2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS07040
gene id: 594679:SD28_RS07040
uniprot id: A0A0A8E709
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

594679:SD28 RS02545
gene id: 594679:SD28_RS02545
uniprot id: A0A0A8E341
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

594679:SD28 RS07465
gene id: 594679:SD28_RS07465
uniprot id: A0A0A8E666
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

594679:SD28 RS03360
gene id: 594679:SD28_RS03360
uniprot id: A0A0A8E468
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

594679:SD28 RS04225
gene id: 594679:SD28_RS04225
uniprot id: A0A0A8E5L7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS00705
gene id: 594679:SD28_RS00705
uniprot id: A0A0A8E246
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

594679:SD28 RS03760
gene id: 594679:SD28_RS03760
uniprot id: A0A0A8E4C1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

594679:SD28 RS06955
gene id: 594679:SD28_RS06955
uniprot id: A0A0A8EB24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

594679:SD28 RS06805
gene id: 594679:SD28_RS06805
uniprot id: A0A0A8E5R0
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS06365
gene id: 594679:SD28_RS06365
uniprot id: A0A0A8E5J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

594679:SD28 RS02460
gene id: 594679:SD28_RS02460
uniprot id: A0A0A8E3Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

594679:SD28 RS06590
gene id: 594679:SD28_RS06590
uniprot id: A0A0A8E4Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

594679:SD28 RS01455
gene id: 594679:SD28_RS01455
uniprot id: A0A0A8E2H9
names: Similarity
messages: Belongs to the UPF0235 family.

594679:SD28 RS02915
gene id: 594679:SD28_RS02915
uniprot id: A0A0A8E379
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

594679:SD28 RS00135
gene id: 594679:SD28_RS00135
uniprot id: A0A0A8E7Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

594679:SD28 RS02225
gene id: 594679:SD28_RS02225
uniprot id: A0A0A8E3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

594679:SD28 RS04880
gene id: 594679:SD28_RS04880
uniprot id: A0A0A8E4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

594679:SD28 RS02690
gene id: 594679:SD28_RS02690
uniprot id: A0A0A8E4Y4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

594679:SD28 RS00055
gene id: 594679:SD28_RS00055
uniprot id: A0A0A8E3I6
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

594679:SD28 RS04815
gene id: 594679:SD28_RS04815
uniprot id: A0A0A8E472
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

594679:SD28 RS07310
gene id: 594679:SD28_RS07310
uniprot id: A0A0A8E5Z3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

594679:SD28 RS02450
gene id: 594679:SD28_RS02450
uniprot id: A0A0A8E8Z3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS01870
gene id: 594679:SD28_RS01870
uniprot id: A0A0A8EBK7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

594679:SD28 RS02140
gene id: 594679:SD28_RS02140
uniprot id: A0A0A8E3G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

594679:SD28 RS03705
gene id: 594679:SD28_RS03705
uniprot id: A0A0A8E3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

594679:SD28 RS06325
gene id: 594679:SD28_RS06325
uniprot id: A0A0A8E4V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

594679:SD28 RS05955
gene id: 594679:SD28_RS05955
uniprot id: A0A0A8E6I5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

594679:SD28 RS06080
gene id: 594679:SD28_RS06080
uniprot id: A0A0A8EAN2
names: Similarity
messages: Belongs to the pyruvate kinase family.

594679:SD28 RS04990
gene id: 594679:SD28_RS04990
uniprot id: A0A0A8E505
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

594679:SD28 RS04765
gene id: 594679:SD28_RS04765
uniprot id: A0A0A8E461
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

594679:SD28 RS07080
gene id: 594679:SD28_RS07080
uniprot id: A0A0A8E5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

594679:SD28 RS05425
gene id: 594679:SD28_RS05425
uniprot id: A0A0A8E558
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS00495
gene id: 594679:SD28_RS00495
uniprot id: A0A0A8E2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

594679:SD28 RS03455
gene id: 594679:SD28_RS03455
uniprot id: A0A0A8E3F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

594679:SD28 RS03425
gene id: 594679:SD28_RS03425
uniprot id: L8BT06
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

594679:SD28 RS03750
gene id: 594679:SD28_RS03750
uniprot id: A0A0A8E6G5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

594679:SD28 RS07605
gene id: 594679:SD28_RS07605
uniprot id: A0A0A8E648
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

594679:SD28 RS05360
gene id: 594679:SD28_RS05360
uniprot id: A0A0A8EAD4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

594679:SD28 RS02815
gene id: 594679:SD28_RS02815
uniprot id: A0A0A8E3U1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

594679:SD28 RS05760
gene id: 594679:SD28_RS05760
uniprot id: A0A0A8E6G1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

594679:SD28 RS00785
gene id: 594679:SD28_RS00785
uniprot id: A0A0A8E259
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

594679:SD28 RS02000
gene id: 594679:SD28_RS02000
uniprot id: A0A0A8E2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

594679:SD28 RS06845
gene id: 594679:SD28_RS06845
uniprot id: A0A0A8E535
names: Similarity
messages: Belongs to the NAPRTase family.

594679:SD28 RS03665
gene id: 594679:SD28_RS03665
uniprot id: A0A0A8E462
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

594679:SD28 RS01885
gene id: 594679:SD28_RS01885
uniprot id: A0A0A8E3F9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

594679:SD28 RS03465
gene id: 594679:SD28_RS03465
uniprot id: A0A0A8E579
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

594679:SD28 RS02305
gene id: 594679:SD28_RS02305
uniprot id: A0A0A8E7G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

594679:SD28 RS05010
gene id: 594679:SD28_RS05010
uniprot id: A0A0A8E4W1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

594679:SD28 RS01545
gene id: 594679:SD28_RS01545
uniprot id: A0A0A8E377
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

594679:SD28 RS06475
gene id: 594679:SD28_RS06475
uniprot id: A0A0A8E6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

594679:SD28 RS05285
gene id: 594679:SD28_RS05285
uniprot id: A0A0A8E542
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

594679:SD28 RS02350
gene id: 594679:SD28_RS02350
uniprot id: A0A0A8E8Y1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

594679:SD28 RS04335
gene id: 594679:SD28_RS04335
uniprot id: A0A0A8E4G3
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

594679:SD28 RS03880
gene id: 594679:SD28_RS03880
uniprot id: A0A0A8E5F1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

594679:SD28 RS04455
gene id: 594679:SD28_RS04455
uniprot id: A0A0A8E3Y6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

594679:SD28 RS06060
gene id: 594679:SD28_RS06060
uniprot id: A0A0A8E6K2
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

594679:SD28 RS02535
gene id: 594679:SD28_RS02535
uniprot id: A0A0A8E3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

594679:SD28 RS06535
gene id: 594679:SD28_RS06535
uniprot id: A0A0A8E6S8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

594679:SD28 RS01890
gene id: 594679:SD28_RS01890
uniprot id: A0A0A8E2R7
names: Similarity
messages: Belongs to the aspartokinase family.

594679:SD28 RS02590
gene id: 594679:SD28_RS02590
uniprot id: A0A0A8E344
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

594679:SD28 RS06355
gene id: 594679:SD28_RS06355
uniprot id: A0A0A8EAR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

594679:SD28 RS00295
gene id: 594679:SD28_RS00295
uniprot id: A0A0A8E1X3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

594679:SD28 RS03355
gene id: 594679:SD28_RS03355
uniprot id: A0A0A8E7G6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS05685
gene id: 594679:SD28_RS05685
uniprot id: A0A0A8E590
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

594679:SD28 RS06455
gene id: 594679:SD28_RS06455
uniprot id: A0A0A8E5L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

594679:SD28 RS07320
gene id: 594679:SD28_RS07320
uniprot id: A0A0A8E5E0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

594679:SD28 RS07170
gene id: 594679:SD28_RS07170
uniprot id: A0A0A8EB67
names: Similarity
messages: Belongs to the peptidase S49 family.

594679:SD28 RS04915
gene id: 594679:SD28_RS04915
uniprot id: A0A0A8EA33
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

594679:SD28 RS07135
gene id: 594679:SD28_RS07135
uniprot id: A0A0A8E5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

594679:SD28 RS03820
gene id: 594679:SD28_RS03820
uniprot id: A0A0A8E3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

594679:SD28 RS02960
gene id: 594679:SD28_RS02960
uniprot id: A0A0A8E416
names: Similarity
messages: Belongs to the NusB family.

594679:SD28 RS03230
gene id: 594679:SD28_RS03230
uniprot id: A0A0A8E543
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

594679:SD28 RS07130
gene id: 594679:SD28_RS07130
uniprot id: A0A0A8E5V8
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04045
gene id: 594679:SD28_RS04045
uniprot id: A0A0A8E9K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

594679:SD28 RS04485
gene id: 594679:SD28_RS04485
uniprot id: A0A0A8E3Z3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

594679:SD28 RS02295
gene id: 594679:SD28_RS02295
uniprot id: A0A0A8E8W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

594679:SD28 RS06900
gene id: 594679:SD28_RS06900
uniprot id: A0A0A8EB11
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04805
gene id: 594679:SD28_RS04805
uniprot id: A0A0A8E4R7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

594679:SD28 RS05455
gene id: 594679:SD28_RS05455
uniprot id: A0A0A8E561
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

594679:SD28 RS01060
gene id: 594679:SD28_RS01060
uniprot id: A0A0A8E2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

594679:SD28 RS00525
gene id: 594679:SD28_RS00525
uniprot id: A0A0A8E2N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

594679:SD28 RS00635
gene id: 594679:SD28_RS00635
uniprot id: A0A0A8E3S2
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS02630
gene id: 594679:SD28_RS02630
uniprot id: A0A0A8E3S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS00100
gene id: 594679:SD28_RS00100
uniprot id: A0A0A8E2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

594679:SD28 RS01950
gene id: 594679:SD28_RS01950
uniprot id: A0A0A8E8N5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

594679:SD28 RS02415
gene id: 594679:SD28_RS02415
uniprot id: A0A0A8E3U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

594679:SD28 RS06195
gene id: 594679:SD28_RS06195
uniprot id: A0A0A8E5G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

594679:SD28 RS01660
gene id: 594679:SD28_RS01660
uniprot id: A0A0A8E4B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

594679:SD28 RS05260
gene id: 594679:SD28_RS05260
uniprot id: A0A0A8E589
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

594679:SD28 RS02760
gene id: 594679:SD28_RS02760
uniprot id: A0A0A8E3Z0
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS03470
gene id: 594679:SD28_RS03470
uniprot id: A0A0A8E434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

594679:SD28 RS00790
gene id: 594679:SD28_RS00790
uniprot id: A0A0A8E806
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

594679:SD28 RS00010
gene id: 594679:SD28_RS00010
uniprot id: A0A0A8E1S6
names: Similarity
messages: Belongs to the UPF0102 family.

594679:SD28 RS05210
gene id: 594679:SD28_RS05210
uniprot id: A0A0A8E581
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

594679:SD28 RS02735
gene id: 594679:SD28_RS02735
uniprot id: A0A0A8E3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

594679:SD28 RS06905
gene id: 594679:SD28_RS06905
uniprot id: A0A0A8E6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

594679:SD28 RS07030
gene id: 594679:SD28_RS07030
uniprot id: A0A0A8E566
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

594679:SD28 RS01955
gene id: 594679:SD28_RS01955
uniprot id: A0A0A8E8N5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

594679:SD28 RS05555
gene id: 594679:SD28_RS05555
uniprot id: A0A0A8EAF5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

594679:SD28 RS00585
gene id: 594679:SD28_RS00585
uniprot id: A0A0A8E2T2
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

594679:SD28 RS00560
gene id: 594679:SD28_RS00560
uniprot id: A0A0A8E2S8
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

594679:SD28 RS03145
gene id: 594679:SD28_RS03145
uniprot id: A0A0A8E532
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

594679:SD28 RS00115
gene id: 594679:SD28_RS00115
uniprot id: A0A0A8E3J5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

594679:SD28 RS03490
gene id: 594679:SD28_RS03490
uniprot id: A0A0A8E9B9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

594679:SD28 RS04675
gene id: 594679:SD28_RS04675
uniprot id: A0A0A8E5U9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

594679:SD28 RS02325
gene id: 594679:SD28_RS02325
uniprot id: A0A0A8E8X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

594679:SD28 RS02025
gene id: 594679:SD28_RS02025
uniprot id: A0A0A8E2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

594679:SD28 RS05820
gene id: 594679:SD28_RS05820
uniprot id: A0A0A8E5B2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

594679:SD28 RS00895
gene id: 594679:SD28_RS00895
uniprot id: A0A0A8E830
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

594679:SD28 RS02720
gene id: 594679:SD28_RS02720
uniprot id: A0A0A8E919
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

594679:SD28 RS02525
gene id: 594679:SD28_RS02525
uniprot id: A0A0A8E901
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

594679:SD28 RS00225
gene id: 594679:SD28_RS00225
uniprot id: A0A0A8E3K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

594679:SD28 RS06370
gene id: 594679:SD28_RS06370
uniprot id: A0A0A8E5N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

594679:SD28 RS07300
gene id: 594679:SD28_RS07300
uniprot id: A0A0A8EB92
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS02440
gene id: 594679:SD28_RS02440
uniprot id: A0A0A8E3V0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

594679:SD28 RS02255
gene id: 594679:SD28_RS02255
uniprot id: A0A0A8E3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

594679:SD28 RS02905
gene id: 594679:SD28_RS02905
uniprot id: A0A0A8E3V4
names: Similarity
messages: Belongs to the CvfB family.

594679:SD28 RS00935
gene id: 594679:SD28_RS00935
uniprot id: A0A0A8E837
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05650
gene id: 594679:SD28_RS05650
uniprot id: A0A0A8E587
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

594679:SD28 RS05215
gene id: 594679:SD28_RS05215
uniprot id: A0A0A8E4G5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

594679:SD28 RS05600
gene id: 594679:SD28_RS05600
uniprot id: A0A0A8E4K2
names: Similarity
messages: Belongs to the PhoH family.

594679:SD28 RS06245
gene id: 594679:SD28_RS06245
uniprot id: A0A0A8E5H7
names: Subcellular Location Annotation
messages: Cytoplasm

594679:SD28 RS07020
gene id: 594679:SD28_RS07020
uniprot id: A0A0A8E5X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

594679:SD28 RS03830
gene id: 594679:SD28_RS03830
uniprot id: A0A0A8E5D9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

594679:SD28 RS06280
gene id: 594679:SD28_RS06280
uniprot id: A0A0A8E5I1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

594679:SD28 RS07000
gene id: 594679:SD28_RS07000
uniprot id: A0A0A8E562
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

594679:SD28 RS01355
gene id: 594679:SD28_RS01355
uniprot id: A0A0A8EBK0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

594679:SD28 RS00360
gene id: 594679:SD28_RS00360
uniprot id: A0A0A8E3M7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

594679:SD28 RS02190
gene id: 594679:SD28_RS02190
uniprot id: A0A0A8E4M4
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS02445
gene id: 594679:SD28_RS02445
uniprot id: A0A0A8E332
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

594679:SD28 RS05170
gene id: 594679:SD28_RS05170
uniprot id: A0A0A8EAA6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

594679:SD28 RS02640
gene id: 594679:SD28_RS02640
uniprot id: A0A0A8E349
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

594679:SD28 RS00505
gene id: 594679:SD28_RS00505
uniprot id: A0A0A8E2S1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

594679:SD28 RS01045
gene id: 594679:SD28_RS01045
uniprot id: A0A0A8E296
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

594679:SD28 RS00590
gene id: 594679:SD28_RS00590
uniprot id: A0A0A8E228
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

594679:SD28 RS00045
gene id: 594679:SD28_RS00045
uniprot id: A0A0A8E1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

594679:SD28 RS07015
gene id: 594679:SD28_RS07015
uniprot id: A0A0A8E5T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

594679:SD28 RS03375
gene id: 594679:SD28_RS03375
uniprot id: A0A0A8E9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

594679:SD28 RS05320
gene id: 594679:SD28_RS05320
uniprot id: A0A0A8E545
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

594679:SD28 RS00580
gene id: 594679:SD28_RS00580
uniprot id: A0A0A8E2P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

594679:SD28 RS04840
gene id: 594679:SD28_RS04840
uniprot id: A0A0A8E4X6
names: Similarity
messages: Belongs to the UPF0250 family.

594679:SD28 RS03860
gene id: 594679:SD28_RS03860
uniprot id: A0A0A8E493
names: Similarity
messages: Belongs to the LOG family.

594679:SD28 RS00355
gene id: 594679:SD28_RS00355
uniprot id: A0A0A8E7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

594679:SD28 RS06810
gene id: 594679:SD28_RS06810
uniprot id: A0A0A8E5U6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

594679:SD28 RS01055
gene id: 594679:SD28_RS01055
uniprot id: A0A0A8E408
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

594679:SD28 RS00500
gene id: 594679:SD28_RS00500
uniprot id: A0A0A8E7D7
names: Similarity
messages: Belongs to the GSP E family.

594679:SD28 RS01580
gene id: 594679:SD28_RS01580
uniprot id: A0A0A8E8F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

594679:SD28 RS06940
gene id: 594679:SD28_RS06940
uniprot id: A0A0A8E5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

594679:SD28 RS07435
gene id: 594679:SD28_RS07435
uniprot id: L8BTZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

594679:SD28 RS02340
gene id: 594679:SD28_RS02340
uniprot id: A0A0A8E3T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

594679:SD28 RS05565
gene id: 594679:SD28_RS05565
uniprot id: A0A0A8E575
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

594679:SD28 RS07120
gene id: 594679:SD28_RS07120
uniprot id: A0A0A8EB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

594679:SD28 RS07540
gene id: 594679:SD28_RS07540
uniprot id: A0A0A8E790
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

594679:SD28 RS04845
gene id: 594679:SD28_RS04845
uniprot id: A0A0A8EBP1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

594679:SD28 RS05160
gene id: 594679:SD28_RS05160
uniprot id: A0A0A8E569
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

594679:SD28 RS05245
gene id: 594679:SD28_RS05245
uniprot id: A0A0A8EAB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

594679:SD28 RS00005
gene id: 594679:SD28_RS00005
uniprot id: A0A0A8E5L6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

594679:SD28 RS02010
gene id: 594679:SD28_RS02010
uniprot id: A0A0A8E4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS05100
gene id: 594679:SD28_RS05100
uniprot id: A0A0A8E644
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

594679:SD28 RS05505
gene id: 594679:SD28_RS05505
uniprot id: A0A0A8E6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

594679:SD28 RS06465
gene id: 594679:SD28_RS06465
uniprot id: A0A0A8E4X9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

594679:SD28 RS02485
gene id: 594679:SD28_RS02485
uniprot id: A0A0A8E3Q6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

594679:SD28 RS04265
gene id: 594679:SD28_RS04265
uniprot id: A0A0A8E4J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

594679:SD28 RS03870
gene id: 594679:SD28_RS03870
uniprot id: A0A0A8E3L9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

594679:SD28 RS03775
gene id: 594679:SD28_RS03775
uniprot id: A0A0A8E5C9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

594679:SD28 RS06435
gene id: 594679:SD28_RS06435
uniprot id: A0A0A8E5P7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

594679:SD28 RS01650
gene id: 594679:SD28_RS01650
uniprot id: A0A0A8E2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

594679:SD28 RS01895
gene id: 594679:SD28_RS01895
uniprot id: A0A0A8E8M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS07305
gene id: 594679:SD28_RS07305
uniprot id: A0A0A8E758
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

594679:SD28 RS03415
gene id: 594679:SD28_RS03415
uniprot id: A0A0A8E570
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS02185
gene id: 594679:SD28_RS02185
uniprot id: A0A0A8E8S9
names: Similarity
messages: Belongs to the WrbA family.

594679:SD28 RS05560
gene id: 594679:SD28_RS05560
uniprot id: A0A0A8E6D9
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

594679:SD28 RS05120
gene id: 594679:SD28_RS05120
uniprot id: A0A0A8EA71
names: Similarity
messages: Belongs to the DEAD box helicase family.

594679:SD28 RS00735
gene id: 594679:SD28_RS00735
uniprot id: A0A0A8E7Z6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

594679:SD28 RS00835
gene id: 594679:SD28_RS00835
uniprot id: A0A0A8E2X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

594679:SD28 RS03630
gene id: 594679:SD28_RS03630
uniprot id: A0A0A8E5A2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

594679:SD28 RS05090
gene id: 594679:SD28_RS05090
uniprot id: A0A0A8E4C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

594679:SD28 RS00810
gene id: 594679:SD28_RS00810
uniprot id: A0A0A8E264
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

594679:SD28 RS04875
gene id: 594679:SD28_RS04875
uniprot id: A0A0A8E4S9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

594679:SD28 RS04375
gene id: 594679:SD28_RS04375
uniprot id: A0A0A8E3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS04210
gene id: 594679:SD28_RS04210
uniprot id: A0A0A8E4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

594679:SD28 RS07180
gene id: 594679:SD28_RS07180
uniprot id: A0A0A8E5W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

594679:SD28 RS06850
gene id: 594679:SD28_RS06850
uniprot id: A0A0A8EB02
names: Similarity
messages: Belongs to the arginase family.

594679:SD28 RS00260
gene id: 594679:SD28_RS00260
uniprot id: A0A0A8E2N2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

594679:SD28 RS00760
gene id: 594679:SD28_RS00760
uniprot id: A0A0A8E800
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

594679:SD28 RS03135
gene id: 594679:SD28_RS03135
uniprot id: A0A0A8E3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

594679:SD28 RS06150
gene id: 594679:SD28_RS06150
uniprot id: A0A0A8E6L7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

594679:SD28 RS06825
gene id: 594679:SD28_RS06825
uniprot id: A0A0A8E6I4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

594679:SD28 RS05045
gene id: 594679:SD28_RS05045
uniprot id: A0A0A8EBP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

594679:SD28 RS02595
gene id: 594679:SD28_RS02595
uniprot id: A0A0A8E907
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

594679:SD28 RS07570
gene id: 594679:SD28_RS07570
uniprot id: A0A0A8E796
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

594679:SD28 RS06545
gene id: 594679:SD28_RS06545
uniprot id: A0A0A8E5R4
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

594679:SD28 RS04650
gene id: 594679:SD28_RS04650
uniprot id: A0A0A8E5U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS06990
gene id: 594679:SD28_RS06990
uniprot id: A0A0A8E5T6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

594679:SD28 RS01335
gene id: 594679:SD28_RS01335
uniprot id: A0A0A8E2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

594679:SD28 RS00090
gene id: 594679:SD28_RS00090
uniprot id: A0A0A8E3J1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

594679:SD28 RS05935
gene id: 594679:SD28_RS05935
uniprot id: A0A0A8E5D0
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04055
gene id: 594679:SD28_RS04055
uniprot id: A0A0A8E4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

594679:SD28 RS01815
gene id: 594679:SD28_RS01815
uniprot id: A0A0A8E4E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

594679:SD28 RS01390
gene id: 594679:SD28_RS01390
uniprot id: A0A0A8E353
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

594679:SD28 RS03950
gene id: 594679:SD28_RS03950
uniprot id: A0A0A8E3N0
names: Similarity
messages: Belongs to the peptidase C59 family.

594679:SD28 RS04405
gene id: 594679:SD28_RS04405
uniprot id: A0A0A8E3X4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

594679:SD28 RS03615
gene id: 594679:SD28_RS03615
uniprot id: A0A0A8E499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

594679:SD28 RS01365
gene id: 594679:SD28_RS01365
uniprot id: A0A0A8E2G0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

594679:SD28 RS04980
gene id: 594679:SD28_RS04980
uniprot id: A0A0A8E613
names: Similarity
messages: Belongs to the transposase 7 family.

594679:SD28 RS07190
gene id: 594679:SD28_RS07190
uniprot id: A0A0A8E5A5
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05465
gene id: 594679:SD28_RS05465
uniprot id: A0A0A8E4I9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

594679:SD28 RS02195
gene id: 594679:SD28_RS02195
uniprot id: A0A0A8E3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

594679:SD28 RS03235
gene id: 594679:SD28_RS03235
uniprot id: A0A0A8E400
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

594679:SD28 RS05740
gene id: 594679:SD28_RS05740
uniprot id: A0A0A8E5A1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

594679:SD28 RS00700
gene id: 594679:SD28_RS00700
uniprot id: A0A0A8E2U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

594679:SD28 RS04930
gene id: 594679:SD28_RS04930
uniprot id: A0A0A8E4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS02335
gene id: 594679:SD28_RS02335
uniprot id: A0A0A8E3N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

594679:SD28 RS04020
gene id: 594679:SD28_RS04020
uniprot id: L8BTD6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

594679:SD28 RS07640
gene id: 594679:SD28_RS07640
uniprot id: A0A0A8E695
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

594679:SD28 RS06915
gene id: 594679:SD28_RS06915
uniprot id: A0A0A8E5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

594679:SD28 RS00385
gene id: 594679:SD28_RS00385
uniprot id: A0A0A8E3N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

594679:SD28 RS01745
gene id: 594679:SD28_RS01745
uniprot id: A0A0A8E3C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

594679:SD28 RS01620
gene id: 594679:SD28_RS01620
uniprot id: A0A0A8E394
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

594679:SD28 RS05905
gene id: 594679:SD28_RS05905
uniprot id: A0A0A8E5C5
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS01005
gene id: 594679:SD28_RS01005
uniprot id: A0A0A8E2Z6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

594679:SD28 RS02635
gene id: 594679:SD28_RS02635
uniprot id: A0A0A8E3X6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

594679:SD28 RS02045
gene id: 594679:SD28_RS02045
uniprot id: A0A0A8E3E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

594679:SD28 RS06945
gene id: 594679:SD28_RS06945
uniprot id: A0A0A8E5W8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

594679:SD28 RS04320
gene id: 594679:SD28_RS04320
uniprot id: A0A0A8E3V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

594679:SD28 RS02470
gene id: 594679:SD28_RS02470
uniprot id: A0A0A8E335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

594679:SD28 RS06515
gene id: 594679:SD28_RS06515
uniprot id: A0A0A8E5L9
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

594679:SD28 RS06105
gene id: 594679:SD28_RS06105
uniprot id: A0A0A8E5J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

594679:SD28 RS02880
gene id: 594679:SD28_RS02880
uniprot id: A0A0A8E3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS05730
gene id: 594679:SD28_RS05730
uniprot id: A0A0A8EAH7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04175
gene id: 594679:SD28_RS04175
uniprot id: A0A0A8E5K6
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS02310
gene id: 594679:SD28_RS02310
uniprot id: A0A0A8E3M4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

594679:SD28 RS01145
gene id: 594679:SD28_RS01145
uniprot id: A0A0A8E2X7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04190
gene id: 594679:SD28_RS04190
uniprot id: A0A0A8E3S3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

594679:SD28 RS00880
gene id: 594679:SD28_RS00880
uniprot id: A0A0A8E2T8
names: Similarity
messages: Belongs to the citrate synthase family.

594679:SD28 RS00990
gene id: 594679:SD28_RS00990
uniprot id: A0A0A8E848
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

594679:SD28 RS00860
gene id: 594679:SD28_RS00860
uniprot id: A0A0A8E2X6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

594679:SD28 RS04080
gene id: 594679:SD28_RS04080
uniprot id: A0A0A8E4C2
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS00375
gene id: 594679:SD28_RS00375
uniprot id: A0A0A8E1Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

594679:SD28 RS07645
gene id: 594679:SD28_RS07645
uniprot id: A0A0A8E5J8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

594679:SD28 RS06490
gene id: 594679:SD28_RS06490
uniprot id: A0A0A8E5L4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

594679:SD28 RS00060
gene id: 594679:SD28_RS00060
uniprot id: A0A0A8E2G2
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

594679:SD28 RS02685
gene id: 594679:SD28_RS02685
uniprot id: A0A0A8E915
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

594679:SD28 RS06260
gene id: 594679:SD28_RS06260
uniprot id: A0A0A8E5M0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

594679:SD28 RS02430
gene id: 594679:SD28_RS02430
uniprot id: A0A0A8E4V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

594679:SD28 RS05645
gene id: 594679:SD28_RS05645
uniprot id: A0A0A8E6E9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

594679:SD28 RS05720
gene id: 594679:SD28_RS05720
uniprot id: A0A0A8E6L5
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS03140
gene id: 594679:SD28_RS03140
uniprot id: A0A0A8E971
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS02280
gene id: 594679:SD28_RS02280
uniprot id: A0A0A8E3K4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

594679:SD28 RS01070
gene id: 594679:SD28_RS01070
uniprot id: A0A0A8E303
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

594679:SD28 RS07360
gene id: 594679:SD28_RS07360
uniprot id: A0A0A8EBA6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

594679:SD28 RS06300
gene id: 594679:SD28_RS06300
uniprot id: A0A0A8E6N8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

594679:SD28 RS01080
gene id: 594679:SD28_RS01080
uniprot id: A0A0A8E866
names: Similarity
messages: Belongs to the Skp family.

594679:SD28 RS00800
gene id: 594679:SD28_RS00800
uniprot id: A0A0A8E2S6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

594679:SD28 RS01405
gene id: 594679:SD28_RS01405
uniprot id: A0A0A8E474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

594679:SD28 RS06815
gene id: 594679:SD28_RS06815
uniprot id: A0A0A8E531
names: Similarity
messages: Belongs to the ArsC family.

594679:SD28 RS03580
gene id: 594679:SD28_RS03580
uniprot id: A0A0A8E450
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

594679:SD28 RS01550
gene id: 594679:SD28_RS01550
uniprot id: A0A0A8E2J0
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04550
gene id: 594679:SD28_RS04550
uniprot id: A0A0A8E5S6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

594679:SD28 RS01020
gene id: 594679:SD28_RS01020
uniprot id: A0A0A8E855
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

594679:SD28 RS01795
gene id: 594679:SD28_RS01795
uniprot id: A0A0A8E385
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

594679:SD28 RS05470
gene id: 594679:SD28_RS05470
uniprot id: A0A0A8EAE6
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS01965
gene id: 594679:SD28_RS01965
uniprot id: A0A0A8E7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS00485
gene id: 594679:SD28_RS00485
uniprot id: A0A0A8E7W0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

594679:SD28 RS04410
gene id: 594679:SD28_RS04410
uniprot id: A0A0A8E9T3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS02360
gene id: 594679:SD28_RS02360
uniprot id: A0A0A8E3N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

594679:SD28 RS00150
gene id: 594679:SD28_RS00150
uniprot id: A0A0A8E2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

594679:SD28 RS05805
gene id: 594679:SD28_RS05805
uniprot id: A0A0A8E4M9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS06440
gene id: 594679:SD28_RS06440
uniprot id: A0A0A8E4X4
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

594679:SD28 RS01290
gene id: 594679:SD28_RS01290
uniprot id: A0A0A8E2Z9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

594679:SD28 RS00175
gene id: 594679:SD28_RS00175
uniprot id: A0A0A8E2I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

594679:SD28 RS05885
gene id: 594679:SD28_RS05885
uniprot id: A0A0A8E5G8
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05000
gene id: 594679:SD28_RS05000
uniprot id: A0A0A8EA47
names: Subcellular Location Annotation
messages: Nucleus

594679:SD28 RS00515
gene id: 594679:SD28_RS00515
uniprot id: A0A0A8E7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

594679:SD28 RS02355
gene id: 594679:SD28_RS02355
uniprot id: A0A0A8E4T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

594679:SD28 RS06470
gene id: 594679:SD28_RS06470
uniprot id: A0A0A8EAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

594679:SD28 RS06885
gene id: 594679:SD28_RS06885
uniprot id: A0A0A8E5S2
names: Similarity
messages: Belongs to the CFA/CMAS family.

594679:SD28 RS04120
gene id: 594679:SD28_RS04120
uniprot id: A0A0A8E9M2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

594679:SD28 RS00490
gene id: 594679:SD28_RS00490
uniprot id: A0A0A8E3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS00255
gene id: 594679:SD28_RS00255
uniprot id: A0A0A8E2J2
names: Similarity
messages: Belongs to the MlaA family.

594679:SD28 RS05055
gene id: 594679:SD28_RS05055
uniprot id: A0A0A8E4W8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

594679:SD28 RS02900
gene id: 594679:SD28_RS02900
uniprot id: A0A0A8E506
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS06030
gene id: 594679:SD28_RS06030
uniprot id: A0A0A8EAM4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

594679:SD28 RS05605
gene id: 594679:SD28_RS05605
uniprot id: A0A0A8EAG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

594679:SD28 RS06135
gene id: 594679:SD28_RS06135
uniprot id: A0A0A8E5K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

594679:SD28 RS06015
gene id: 594679:SD28_RS06015
uniprot id: A0A0A8E5E2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS00380
gene id: 594679:SD28_RS00380
uniprot id: A0A0A8E7U7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS01655
gene id: 594679:SD28_RS01655
uniprot id: A0A0A8E8H4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

594679:SD28 RS07680
gene id: 594679:SD28_RS07680
uniprot id: A0A0A8E7B8
names: Similarity
messages: Belongs to the ParB family.

594679:SD28 RS03225
gene id: 594679:SD28_RS03225
uniprot id: A0A0A8E984
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

594679:SD28 RS03385
gene id: 594679:SD28_RS03385
uniprot id: A0A0A8E422
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

594679:SD28 RS00855
gene id: 594679:SD28_RS00855
uniprot id: A0A0A8E2T4
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

594679:SD28 RS00850
gene id: 594679:SD28_RS00850
uniprot id: A0A0A8E3W8
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

594679:SD28 RS01140
gene id: 594679:SD28_RS01140
uniprot id: A0A0A8E424
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

594679:SD28 RS04760
gene id: 594679:SD28_RS04760
uniprot id: A0A0A8E4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

594679:SD28 RS04745
gene id: 594679:SD28_RS04745
uniprot id: A0A0A8EA05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

594679:SD28 RS02435
gene id: 594679:SD28_RS02435
uniprot id: L8BSU7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

594679:SD28 RS02665
gene id: 594679:SD28_RS02665
uniprot id: A0A0A8E3S4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

594679:SD28 RS02970
gene id: 594679:SD28_RS02970
uniprot id: A0A0A8E951
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

594679:SD28 RS01240
gene id: 594679:SD28_RS01240
uniprot id: A0A0A8E328
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS03730
gene id: 594679:SD28_RS03730
uniprot id: A0A0A8E3J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS02230
gene id: 594679:SD28_RS02230
uniprot id: A0A0A8E3N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

594679:SD28 RS02265
gene id: 594679:SD28_RS02265
uniprot id: A0A0A8E2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

594679:SD28 RS04865
gene id: 594679:SD28_RS04865
uniprot id: A0A0A8E6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

594679:SD28 RS05325
gene id: 594679:SD28_RS05325
uniprot id: A0A0A8E596
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

594679:SD28 RS04960
gene id: 594679:SD28_RS04960
uniprot id: A0A0A8E4U9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

594679:SD28 RS04170
gene id: 594679:SD28_RS04170
uniprot id: A0A0A8E9N4
names: Caution
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS03815
gene id: 594679:SD28_RS03815
uniprot id: A0A0A8E4C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

594679:SD28 RS05840
gene id: 594679:SD28_RS05840
uniprot id: A0A0A8EAJ4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

594679:SD28 RS00520
gene id: 594679:SD28_RS00520
uniprot id: A0A0A8E3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

594679:SD28 RS02315
gene id: 594679:SD28_RS02315
uniprot id: A0A0A8E3S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

594679:SD28 RS02030
gene id: 594679:SD28_RS02030
uniprot id: A0A0A8E8P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS02250
gene id: 594679:SD28_RS02250
uniprot id: A0A0A8EBL3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

594679:SD28 RS03035
gene id: 594679:SD28_RS03035
uniprot id: A0A0A8E395
names: Similarity
messages: Belongs to the FeoA family.

594679:SD28 RS03105
gene id: 594679:SD28_RS03105
uniprot id: A0A0A8E3A1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS06190
gene id: 594679:SD28_RS06190
uniprot id: A0A0A8E6L9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

594679:SD28 RS03895
gene id: 594679:SD28_RS03895
uniprot id: A0A0A8E3M5
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

594679:SD28 RS01840
gene id: 594679:SD28_RS01840
uniprot id: A0A0A8E8L4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

594679:SD28 RS07115
gene id: 594679:SD28_RS07115
uniprot id: A0A0A8E586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

594679:SD28 RS05680
gene id: 594679:SD28_RS05680
uniprot id: A0A0A8E6F2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

594679:SD28 RS07035
gene id: 594679:SD28_RS07035
uniprot id: A0A0A8EB37
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

594679:SD28 RS04010
gene id: 594679:SD28_RS04010
uniprot id: A0A0A8E3N8
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

594679:SD28 RS00615
gene id: 594679:SD28_RS00615
uniprot id: A0A0A8E2T7
names: Similarity
messages: Belongs to the glutamine synthetase family.

594679:SD28 RS04085
gene id: 594679:SD28_RS04085
uniprot id: A0A0A8E4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

594679:SD28 RS04685
gene id: 594679:SD28_RS04685
uniprot id: A0A0A8E4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS02655
gene id: 594679:SD28_RS02655
uniprot id: A0A0A8E6A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

594679:SD28 RS04595
gene id: 594679:SD28_RS04595
uniprot id: A0A0A8E9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

594679:SD28 RS05225
gene id: 594679:SD28_RS05225
uniprot id: A0A0A8E697
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

594679:SD28 RS04750
gene id: 594679:SD28_RS04750
uniprot id: A0A0A8E5W7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

594679:SD28 RS05255
gene id: 594679:SD28_RS05255
uniprot id: A0A0A8E539
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

594679:SD28 RS06575
gene id: 594679:SD28_RS06575
uniprot id: A0A0A8E6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

594679:SD28 RS03655
gene id: 594679:SD28_RS03655
uniprot id: A0A0A8E9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS03995
gene id: 594679:SD28_RS03995
uniprot id: A0A0A8E5G7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

594679:SD28 RS01340
gene id: 594679:SD28_RS01340
uniprot id: A0A0A8E8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

594679:SD28 RS04730
gene id: 594679:SD28_RS04730
uniprot id: A0A0A8E4Q1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

594679:SD28 RS01450
gene id: 594679:SD28_RS01450
uniprot id: A0A0A8E366
names: Similarity
messages: Belongs to the YggT family.

594679:SD28 RS01995
gene id: 594679:SD28_RS01995
uniprot id: A0A0A8E3I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS04240
gene id: 594679:SD28_RS04240
uniprot id: A0A0A8E3T5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

594679:SD28 RS03585
gene id: 594679:SD28_RS03585
uniprot id: A0A0A8E498
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

594679:SD28 RS04695
gene id: 594679:SD28_RS04695
uniprot id: A0A0A8E9Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

594679:SD28 RS01820
gene id: 594679:SD28_RS01820
uniprot id: A0A0A8E392
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

594679:SD28 RS02365
gene id: 594679:SD28_RS02365
uniprot id: A0A0A8E3T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

594679:SD28 RS05845
gene id: 594679:SD28_RS05845
uniprot id: A0A0A8E6H1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

594679:SD28 RS05795
gene id: 594679:SD28_RS05795
uniprot id: A0A0A8E5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

594679:SD28 RS03445
gene id: 594679:SD28_RS03445
uniprot id: A0A0A8E431
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

594679:SD28 RS03070
gene id: 594679:SD28_RS03070
uniprot id: A0A0A8E428
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VapD ribonuclease family.
messages: Cleaves ssRNA, mostly between U:A.
messages: Homodimer.

594679:SD28 RS01945
gene id: 594679:SD28_RS01945
uniprot id: A0A0A8E2S9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

594679:SD28 RS07460
gene id: 594679:SD28_RS07460
uniprot id: A0A0A8E624
names: Similarity
messages: Belongs to the RNA polymerase alpha chain family.

594679:SD28 RS06215
gene id: 594679:SD28_RS06215
uniprot id: A0A0A8E6M4
names: Similarity
messages: Belongs to the peptidase M16 family.

594679:SD28 RS03840
gene id: 594679:SD28_RS03840
uniprot id: A0A0A8E4D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

594679:SD28 RS05400
gene id: 594679:SD28_RS05400
uniprot id: A0A0A8E554
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

594679:SD28 RS05480
gene id: 594679:SD28_RS05480
uniprot id: A0A0A8E564
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

594679:SD28 RS02385
gene id: 594679:SD28_RS02385
uniprot id: A0A0A8E3P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

594679:SD28 RS03505
gene id: 594679:SD28_RS03505
uniprot id: A0A0A8E439
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS03710
gene id: 594679:SD28_RS03710
uniprot id: A0A0A8E9E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

594679:SD28 RS05005
gene id: 594679:SD28_RS05005
uniprot id: A0A0A8E620
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

594679:SD28 RS00110
gene id: 594679:SD28_RS00110
uniprot id: A0A0A8E7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

594679:SD28 RS03440
gene id: 594679:SD28_RS03440
uniprot id: A0A0A8E574
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

594679:SD28 RS04390
gene id: 594679:SD28_RS04390
uniprot id: A0A0A8E5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

594679:SD28 RS03370
gene id: 594679:SD28_RS03370
uniprot id: A0A0A8E3E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

594679:SD28 RS06275
gene id: 594679:SD28_RS06275
uniprot id: A0A0A8E6N4
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS01275
gene id: 594679:SD28_RS01275
uniprot id: A0A0A8E2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

594679:SD28 RS00655
gene id: 594679:SD28_RS00655
uniprot id: A0A0A8E237
names: Similarity
messages: Belongs to the BolA/IbaG family.

594679:SD28 RS02585
gene id: 594679:SD28_RS02585
uniprot id: A0A0A8E3W9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

594679:SD28 RS01645
gene id: 594679:SD28_RS01645
uniprot id: A0A0A8E399
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

594679:SD28 RS01625
gene id: 594679:SD28_RS01625
uniprot id: A0A0A8E2K9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS06140
gene id: 594679:SD28_RS06140
uniprot id: A0A0A8E4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

594679:SD28 RS06360
gene id: 594679:SD28_RS06360
uniprot id: A0A0A8E6Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

594679:SD28 RS04910
gene id: 594679:SD28_RS04910
uniprot id: A0A0A8E490
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

594679:SD28 RS06935
gene id: 594679:SD28_RS06935
uniprot id: A0A0A8E6Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

594679:SD28 RS04495
gene id: 594679:SD28_RS04495
uniprot id: A0A0A8E5R6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

594679:SD28 RS02810
gene id: 594679:SD28_RS02810
uniprot id: A0A0A8E4Z7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

594679:SD28 RS00050
gene id: 594679:SD28_RS00050
uniprot id: A0A0A8E7P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

594679:SD28 RS04570
gene id: 594679:SD28_RS04570
uniprot id: A0A0A8E9W7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

594679:SD28 RS04400
gene id: 594679:SD28_RS04400
uniprot id: A0A0A8E4M8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

594679:SD28 RS06180
gene id: 594679:SD28_RS06180
uniprot id: A0A0A8E4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

594679:SD28 RS04545
gene id: 594679:SD28_RS04545
uniprot id: A0A0A8E9W2
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS06055
gene id: 594679:SD28_RS06055
uniprot id: A0A0A8EAM8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

594679:SD28 RS02775
gene id: 594679:SD28_RS02775
uniprot id: A0A0A8E4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS07430
gene id: 594679:SD28_RS07430
uniprot id: A0A0A8E661
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04720
gene id: 594679:SD28_RS04720
uniprot id: A0A0A8E9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS02005
gene id: 594679:SD28_RS02005
uniprot id: A0A0A8E8P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS02405
gene id: 594679:SD28_RS02405
uniprot id: A0A0A8E4U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

594679:SD28 RS03220
gene id: 594679:SD28_RS03220
uniprot id: A0A0A8E3B8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

594679:SD28 RS04125
gene id: 594679:SD28_RS04125
uniprot id: A0A0A8E5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

594679:SD28 RS06020
gene id: 594679:SD28_RS06020
uniprot id: A0A0A8E5I8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS01565
gene id: 594679:SD28_RS01565
uniprot id: A0A0A8E334
names: Similarity
messages: Belongs to the glycosyl hydrolase 14 family.

594679:SD28 RS03510
gene id: 594679:SD28_RS03510
uniprot id: A0A0A8E488
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

594679:SD28 RS02235
gene id: 594679:SD28_RS02235
uniprot id: A0A0A8E2Y5
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS00200
gene id: 594679:SD28_RS00200
uniprot id: A0A0A8E2I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

594679:SD28 RS01855
gene id: 594679:SD28_RS01855
uniprot id: A0A0A8E3F4
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS06035
gene id: 594679:SD28_RS06035
uniprot id: A0A0A8E6J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

594679:SD28 RS07665
gene id: 594679:SD28_RS07665
uniprot id: A0A0A8E6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

594679:SD28 RS01135
gene id: 594679:SD28_RS01135
uniprot id: A0A0A8E876
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.

594679:SD28 RS07690
gene id: 594679:SD28_RS07690
uniprot id: A0A0A8E6B0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

594679:SD28 RS06350
gene id: 594679:SD28_RS06350
uniprot id: A0A0A8E4V8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS05380
gene id: 594679:SD28_RS05380
uniprot id: A0A0A8E5A3
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05330
gene id: 594679:SD28_RS05330
uniprot id: A0A0A8E4H5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

594679:SD28 RS03780
gene id: 594679:SD28_RS03780
uniprot id: A0A0A8E479
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

594679:SD28 RS06950
gene id: 594679:SD28_RS06950
uniprot id: A0A0A8E557
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

594679:SD28 RS02625
gene id: 594679:SD28_RS02625
uniprot id: A0A0A8E4X7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS00345
gene id: 594679:SD28_RS00345
uniprot id: A0A0A8E2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

594679:SD28 RS06235
gene id: 594679:SD28_RS06235
uniprot id: A0A0A8EAQ3
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

594679:SD28 RS07555
gene id: 594679:SD28_RS07555
uniprot id: A0A0A8E677
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

594679:SD28 RS03610
gene id: 594679:SD28_RS03610
uniprot id: A0A0A8E453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

594679:SD28 RS02515
gene id: 594679:SD28_RS02515
uniprot id: A0A0A8E3W1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

594679:SD28 RS00230
gene id: 594679:SD28_RS00230
uniprot id: A0A0A8E2I8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

594679:SD28 RS06310
gene id: 594679:SD28_RS06310
uniprot id: A0A0A8E5N0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

594679:SD28 RS02290
gene id: 594679:SD28_RS02290
uniprot id: A0A0A8E306
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

594679:SD28 RS05430
gene id: 594679:SD28_RS05430
uniprot id: A0A0A8E5B0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

594679:SD28 RS01800
gene id: 594679:SD28_RS01800
uniprot id: A0A0A8E3D9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

594679:SD28 RS03215
gene id: 594679:SD28_RS03215
uniprot id: A0A0A8E447
names: Subcellular Location Annotation
messages: Mitochondrion

594679:SD28 RS06770
gene id: 594679:SD28_RS06770
uniprot id: A0A0A8E6W5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

594679:SD28 RS00075
gene id: 594679:SD28_RS00075
uniprot id: A0A0A8E676
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

594679:SD28 RS03790
gene id: 594679:SD28_RS03790
uniprot id: A0A0A8E3K8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS00890
gene id: 594679:SD28_RS00890
uniprot id: A0A0A8E275
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

594679:SD28 RS01535
gene id: 594679:SD28_RS01535
uniprot id: A0A0A8E491
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS03525
gene id: 594679:SD28_RS03525
uniprot id: A0A0A8E588
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS02275
gene id: 594679:SD28_RS02275
uniprot id: A0A0A8E4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

594679:SD28 RS03955
gene id: 594679:SD28_RS03955
uniprot id: A0A0A8E9I9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS02610
gene id: 594679:SD28_RS02610
uniprot id: L8BTZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

594679:SD28 RS00885
gene id: 594679:SD28_RS00885
uniprot id: A0A0A8E2Y1
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04710
gene id: 594679:SD28_RS04710
uniprot id: A0A0A8E4U3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

594679:SD28 RS06335
gene id: 594679:SD28_RS06335
uniprot id: A0A0A8E6P4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

594679:SD28 RS00965
gene id: 594679:SD28_RS00965
uniprot id: A0A0A8E843
names: Similarity
messages: Belongs to the universal stress protein A family.

594679:SD28 RS01755
gene id: 594679:SD28_RS01755
uniprot id: A0A0A8E8J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

594679:SD28 RS00755
gene id: 594679:SD28_RS00755
uniprot id: A0A0A8E254
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

594679:SD28 RS01975
gene id: 594679:SD28_RS01975
uniprot id: A0A0A8E2T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS02455
gene id: 594679:SD28_RS02455
uniprot id: A0A0A8E4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

594679:SD28 RS07655
gene id: 594679:SD28_RS07655
uniprot id: A0A0A8E7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

594679:SD28 RS00970
gene id: 594679:SD28_RS00970
uniprot id: A0A0A8E3Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

594679:SD28 RS01725
gene id: 594679:SD28_RS01725
uniprot id: A0A0A8E2N1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

594679:SD28 RS03210
gene id: 594679:SD28_RS03210
uniprot id: A0A0A8E3Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

594679:SD28 RS02740
gene id: 594679:SD28_RS02740
uniprot id: A0A0A8E358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

594679:SD28 RS04000
gene id: 594679:SD28_RS04000
uniprot id: A0A0A8E4B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

594679:SD28 RS05970
gene id: 594679:SD28_RS05970
uniprot id: A0A0A8E4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

594679:SD28 RS01740
gene id: 594679:SD28_RS01740
uniprot id: A0A0A8E374
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

594679:SD28 RS03740
gene id: 594679:SD28_RS03740
uniprot id: A0A0A8E6C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

594679:SD28 RS05810
gene id: 594679:SD28_RS05810
uniprot id: A0A0A8EAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

594679:SD28 RS03875
gene id: 594679:SD28_RS03875
uniprot id: A0A0A8E9H7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

594679:SD28 RS03770
gene id: 594679:SD28_RS03770
uniprot id: A0A0A8E9F6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

594679:SD28 RS03175
gene id: 594679:SD28_RS03175
uniprot id: A0A0A8E3Z2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

594679:SD28 RS05365
gene id: 594679:SD28_RS05365
uniprot id: A0A0A8E6E4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

594679:SD28 RS06765
gene id: 594679:SD28_RS06765
uniprot id: A0A0A8EAY2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

594679:SD28 RS07370
gene id: 594679:SD28_RS07370
uniprot id: A0A0A8E604
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS06835
gene id: 594679:SD28_RS06835
uniprot id: A0A0A8E5R5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

594679:SD28 RS05250
gene id: 594679:SD28_RS05250
uniprot id: A0A0A8E6A0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

594679:SD28 RS03025
gene id: 594679:SD28_RS03025
uniprot id: A0A0A8E5Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

594679:SD28 RS01305
gene id: 594679:SD28_RS01305
uniprot id: A0A0A8E8B0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS05870
gene id: 594679:SD28_RS05870
uniprot id: A0A0A8EAJ7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04200
gene id: 594679:SD28_RS04200
uniprot id: A0A0A8E5L2
names: Similarity
messages: Belongs to the HesB/IscA family.

594679:SD28 RS06305
gene id: 594679:SD28_RS06305
uniprot id: A0A0A8E5I6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

594679:SD28 RS04690
gene id: 594679:SD28_RS04690
uniprot id: A0A0A8E443
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

594679:SD28 RS02495
gene id: 594679:SD28_RS02495
uniprot id: A0A0A8E337
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

594679:SD28 RS06920
gene id: 594679:SD28_RS06920
uniprot id: A0A0A8E552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

594679:SD28 RS02600
gene id: 594679:SD28_RS02600
uniprot id: A0A0A8E4X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

594679:SD28 RS00840
gene id: 594679:SD28_RS00840
uniprot id: A0A0A8E267
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

594679:SD28 RS04420
gene id: 594679:SD28_RS04420
uniprot id: A0A0A8E4H7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
messages: In the C-terminal section; belongs to the DHPS family.

594679:SD28 RS00125
gene id: 594679:SD28_RS00125
uniprot id: A0A0A8E2L1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

594679:SD28 RS06205
gene id: 594679:SD28_RS06205
uniprot id: A0A0A8E4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

594679:SD28 RS01560
gene id: 594679:SD28_RS01560
uniprot id: A0A0A8E496
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS02370
gene id: 594679:SD28_RS02370
uniprot id: A0A0A8E323
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

594679:SD28 RS05300
gene id: 594679:SD28_RS05300
uniprot id: A0A0A8EAC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS02145
gene id: 594679:SD28_RS02145
uniprot id: A0A0A8E3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

594679:SD28 RS04060
gene id: 594679:SD28_RS04060
uniprot id: A0A0A8E4G0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

594679:SD28 RS00820
gene id: 594679:SD28_RS00820
uniprot id: A0A0A8E3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS00985
gene id: 594679:SD28_RS00985
uniprot id: A0A0A8E288
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

594679:SD28 RS01880
gene id: 594679:SD28_RS01880
uniprot id: A0A0A8E3A4
names: Similarity
messages: Belongs to the group II decarboxylase family.

594679:SD28 RS02380
gene id: 594679:SD28_RS02380
uniprot id: A0A0A8E4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

594679:SD28 RS02390
gene id: 594679:SD28_RS02390
uniprot id: A0A0A8E3U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

594679:SD28 RS03765
gene id: 594679:SD28_RS03765
uniprot id: A0A0A8E3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

594679:SD28 RS04295
gene id: 594679:SD28_RS04295
uniprot id: A0A0A8E3U8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

594679:SD28 RS04640
gene id: 594679:SD28_RS04640
uniprot id: A0A0A8E429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

594679:SD28 RS07210
gene id: 594679:SD28_RS07210
uniprot id: A0A0A8E5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

594679:SD28 RS05165
gene id: 594679:SD28_RS05165
uniprot id: A0A0A8E4F9
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS03810
gene id: 594679:SD28_RS03810
uniprot id: A0A0A8E482
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

594679:SD28 RS02520
gene id: 594679:SD28_RS02520
uniprot id: A0A0A8E340
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS03320
gene id: 594679:SD28_RS03320
uniprot id: A0A0A8E413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

594679:SD28 RS05550
gene id: 594679:SD28_RS05550
uniprot id: A0A0A8E4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

594679:SD28 RS04355
gene id: 594679:SD28_RS04355
uniprot id: A0A0A8E5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

594679:SD28 RS04725
gene id: 594679:SD28_RS04725
uniprot id: A0A0A8E5W1
names: Similarity
messages: Belongs to the BolA/IbaG family.

594679:SD28 RS01435
gene id: 594679:SD28_RS01435
uniprot id: A0A0A8E480
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

594679:SD28 RS04110
gene id: 594679:SD28_RS04110
uniprot id: A0A0A8E4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

594679:SD28 RS07440
gene id: 594679:SD28_RS07440
uniprot id: A0A0A8EBC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

594679:SD28 RS00530
gene id: 594679:SD28_RS00530
uniprot id: A0A0A8E2S4
names: Similarity
messages: Belongs to the ArsC family.

594679:SD28 RS06050
gene id: 594679:SD28_RS06050
uniprot id: A0A0A8E4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

594679:SD28 RS00845
gene id: 594679:SD28_RS00845
uniprot id: A0A0A8E819
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS04735
gene id: 594679:SD28_RS04735
uniprot id: A0A0A8E4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

594679:SD28 RS00120
gene id: 594679:SD28_RS00120
uniprot id: A0A0A8E2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

594679:SD28 RS03980
gene id: 594679:SD28_RS03980
uniprot id: A0A0A8E9J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

594679:SD28 RS06005
gene id: 594679:SD28_RS06005
uniprot id: A0A0A8EAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

594679:SD28 RS05675
gene id: 594679:SD28_RS05675
uniprot id: A0A0A8EAH0
names: Similarity
messages: Belongs to the peptidase M24B family.

594679:SD28 RS03390
gene id: 594679:SD28_RS03390
uniprot id: A0A0A8E6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

594679:SD28 RS04025
gene id: 594679:SD28_RS04025
uniprot id: A0A0A8E7H5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

594679:SD28 RS06210
gene id: 594679:SD28_RS06210
uniprot id: A0A0A8EAQ0
names: Similarity
messages: Belongs to the peptidase M16 family.

594679:SD28 RS00040
gene id: 594679:SD28_RS00040
uniprot id: A0A0A8E2J9
names: Similarity
messages: Belongs to the GARS family.
messages: Belongs to the SAICAR synthetase family.

594679:SD28 RS04680
gene id: 594679:SD28_RS04680
uniprot id: A0A0A8E4N9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

594679:SD28 RS02270
gene id: 594679:SD28_RS02270
uniprot id: A0A0A8E8U8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS00745
gene id: 594679:SD28_RS00745
uniprot id: A0A0A8E2R8
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05195
gene id: 594679:SD28_RS05195
uniprot id: A0A0A8EAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

594679:SD28 RS05780
gene id: 594679:SD28_RS05780
uniprot id: A0A0A8E4M5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

594679:SD28 RS01990
gene id: 594679:SD28_RS01990
uniprot id: A0A0A8E3D4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

594679:SD28 RS05530
gene id: 594679:SD28_RS05530
uniprot id: A0A0A8EAF3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS05785
gene id: 594679:SD28_RS05785
uniprot id: A0A0A8EAI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

594679:SD28 RS05850
gene id: 594679:SD28_RS05850
uniprot id: A0A0A8E5B7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

594679:SD28 RS05790
gene id: 594679:SD28_RS05790
uniprot id: A0A0A8E6G4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

594679:SD28 RS04670
gene id: 594679:SD28_RS04670
uniprot id: A0A0A8E9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS00305
gene id: 594679:SD28_RS00305
uniprot id: A0A0A8E3M0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

594679:SD28 RS05570
gene id: 594679:SD28_RS05570
uniprot id: A0A0A8E5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

594679:SD28 RS07155
gene id: 594679:SD28_RS07155
uniprot id: A0A0A8E5W3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

594679:SD28 RS02620
gene id: 594679:SD28_RS02620
uniprot id: A0A0A8E910
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

594679:SD28 RS04220
gene id: 594679:SD28_RS04220
uniprot id: L8BT08
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

594679:SD28 RS00575
gene id: 594679:SD28_RS00575
uniprot id: A0A0A8E3R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

594679:SD28 RS04585
gene id: 594679:SD28_RS04585
uniprot id: A0A0A8E4R5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS06170
gene id: 594679:SD28_RS06170
uniprot id: A0A0A8E5G5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

594679:SD28 RS04305
gene id: 594679:SD28_RS04305
uniprot id: A0A0A8E5N1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

594679:SD28 RS01575
gene id: 594679:SD28_RS01575
uniprot id: A0A0A8E2J7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

594679:SD28 RS00570
gene id: 594679:SD28_RS00570
uniprot id: A0A0A8E7X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

594679:SD28 RS07425
gene id: 594679:SD28_RS07425
uniprot id: A0A0A8E617
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

594679:SD28 RS07480
gene id: 594679:SD28_RS07480
uniprot id: A0A0A8E787
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS05965
gene id: 594679:SD28_RS05965
uniprot id: A0A0A8E5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

594679:SD28 RS06620
gene id: 594679:SD28_RS06620
uniprot id: A0A0A8E504
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

594679:SD28 RS00750
gene id: 594679:SD28_RS00750
uniprot id: A0A0A8E2V8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

594679:SD28 RS00805
gene id: 594679:SD28_RS00805
uniprot id: A0A0A8E2W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

594679:SD28 RS05405
gene id: 594679:SD28_RS05405
uniprot id: A0A0A8E5A6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

594679:SD28 RS07730
gene id: 594679:SD28_RS07730
uniprot id: A0A0A8E7N4
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

594679:SD28 RS02425
gene id: 594679:SD28_RS02425
uniprot id: A0A0A8E8Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

594679:SD28 RS02130
gene id: 594679:SD28_RS02130
uniprot id: A0A0A8E8R5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

594679:SD28 RS06395
gene id: 594679:SD28_RS06395
uniprot id: A0A0A8E5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

594679:SD28 RS04835
gene id: 594679:SD28_RS04835
uniprot id: A0A0A8E4S4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

594679:SD28 RS05595
gene id: 594679:SD28_RS05595
uniprot id: A0A0A8E5D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

594679:SD28 RS01360
gene id: 594679:SD28_RS01360
uniprot id: A0A0A8E348
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS03865
gene id: 594679:SD28_RS03865
uniprot id: A0A0A8E4D7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

594679:SD28 RS01050
gene id: 594679:SD28_RS01050
uniprot id: A0A0A8E860
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

594679:SD28 RS03940
gene id: 594679:SD28_RS03940
uniprot id: A0A0A8E4A0
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS07420
gene id: 594679:SD28_RS07420
uniprot id: A0A0A8E779
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

594679:SD28 RS04935
gene id: 594679:SD28_RS04935
uniprot id: A0A0A8E495
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

594679:SD28 RS04890
gene id: 594679:SD28_RS04890
uniprot id: A0A0A8EA29
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

594679:SD28 RS02770
gene id: 594679:SD28_RS02770
uniprot id: A0A0A8E926
names: Similarity
messages: Belongs to the FBPase class 2 family.

594679:SD28 RS06065
gene id: 594679:SD28_RS06065
uniprot id: A0A0A8E5E9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

594679:SD28 RS06555
gene id: 594679:SD28_RS06555
uniprot id: A0A0A8EAV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

594679:SD28 RS02015
gene id: 594679:SD28_RS02015
uniprot id: A0A0A8E3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

594679:SD28 RS07050
gene id: 594679:SD28_RS07050
uniprot id: A0A0A8E5Y1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

594679:SD28 RS03745
gene id: 594679:SD28_RS03745
uniprot id: A0A0A8E5C3
names: Similarity
messages: Belongs to the asparaginase 1 family.

594679:SD28 RS06040
gene id: 594679:SD28_RS06040
uniprot id: A0A0A8E5E6
names: Similarity
messages: Belongs to the fabD family.

594679:SD28 RS03725
gene id: 594679:SD28_RS03725
uniprot id: L8BTA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

594679:SD28 RS07075
gene id: 594679:SD28_RS07075
uniprot id: A0A0A8E714
names: Similarity
messages: Belongs to the RecJ family.

594679:SD28 RS00685
gene id: 594679:SD28_RS00685
uniprot id: A0A0A8E7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

594679:SD28 RS00460
gene id: 594679:SD28_RS00460
uniprot id: A0A0A8E7V7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS05690
gene id: 594679:SD28_RS05690
uniprot id: A0A0A8E5E3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

594679:SD28 RS00780
gene id: 594679:SD28_RS00780
uniprot id: A0A0A8E2W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

594679:SD28 RS05500
gene id: 594679:SD28_RS05500
uniprot id: A0A0A8E6K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

594679:SD28 RS00095
gene id: 594679:SD28_RS00095
uniprot id: A0A0A8E2G7
names: Subcellular Location Annotation
messages: Membrane

594679:SD28 RS04515
gene id: 594679:SD28_RS04515
uniprot id: A0A0A8E9V8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

594679:SD28 RS04580
gene id: 594679:SD28_RS04580
uniprot id: A0A0A8E4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

594679:SD28 RS00250
gene id: 594679:SD28_RS00250
uniprot id: A0A0A8E3L4
names: Similarity
messages: Belongs to the DprA/Smf family.

594679:SD28 RS03845
gene id: 594679:SD28_RS03845
uniprot id: A0A0A8E3L5
names: Similarity
messages: Belongs to the glyoxalase I family.

594679:SD28 RS07010
gene id: 594679:SD28_RS07010
uniprot id: A0A0A8E705
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

594679:SD28 RS05445
gene id: 594679:SD28_RS05445
uniprot id: A0A0A8EAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.