593907:CELGI RS07265
gene id: 593907:CELGI_RS07265
uniprot id: F8A3Q1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

593907:CELGI RS09805
gene id: 593907:CELGI_RS09805
uniprot id: F7ZZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS10480
gene id: 593907:CELGI_RS10480
uniprot id: F7ZZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

593907:CELGI RS10025
gene id: 593907:CELGI_RS10025
uniprot id: F7ZZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

593907:CELGI RS12055
gene id: 593907:CELGI_RS12055
uniprot id: F8A1K6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS09505
gene id: 593907:CELGI_RS09505
uniprot id: F8A7I6
names: Similarity
messages: Belongs to the UPF0098 family.

593907:CELGI RS15260
gene id: 593907:CELGI_RS15260
uniprot id: F8A734
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS14760
gene id: 593907:CELGI_RS14760
uniprot id: F8A5Y1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

593907:CELGI RS06875
gene id: 593907:CELGI_RS06875
uniprot id: F8A320
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

593907:CELGI RS08455
gene id: 593907:CELGI_RS08455
uniprot id: F8A5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS02290
gene id: 593907:CELGI_RS02290
uniprot id: F8A5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

593907:CELGI RS02265
gene id: 593907:CELGI_RS02265
uniprot id: F8A5F2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

593907:CELGI RS05835
gene id: 593907:CELGI_RS05835
uniprot id: F8A1C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

593907:CELGI RS00445
gene id: 593907:CELGI_RS00445
uniprot id: F8A2A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

593907:CELGI RS14860
gene id: 593907:CELGI_RS14860
uniprot id: F8A6F3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

593907:CELGI RS04180
gene id: 593907:CELGI_RS04180
uniprot id: F7ZZJ3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

593907:CELGI RS07645
gene id: 593907:CELGI_RS07645
uniprot id: F8A4C6
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS03025
gene id: 593907:CELGI_RS03025
uniprot id: F8A6Q6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS07850
gene id: 593907:CELGI_RS07850
uniprot id: F8A4W4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

593907:CELGI RS04770
gene id: 593907:CELGI_RS04770
uniprot id: F8A0B3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

593907:CELGI RS10060
gene id: 593907:CELGI_RS10060
uniprot id: F7ZZ80
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS14790
gene id: 593907:CELGI_RS14790
uniprot id: F8A6D9
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

593907:CELGI RS01800
gene id: 593907:CELGI_RS01800
uniprot id: F8A4Q9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

593907:CELGI RS14265
gene id: 593907:CELGI_RS14265
uniprot id: F8A579
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

593907:CELGI RS09045
gene id: 593907:CELGI_RS09045
uniprot id: F8A6U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

593907:CELGI RS10605
gene id: 593907:CELGI_RS10605
uniprot id: F8A039
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

593907:CELGI RS13650
gene id: 593907:CELGI_RS13650
uniprot id: F8A4F9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

593907:CELGI RS08915
gene id: 593907:CELGI_RS08915
uniprot id: F8A6C0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

593907:CELGI RS09500
gene id: 593907:CELGI_RS09500
uniprot id: F8A7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

593907:CELGI RS03030
gene id: 593907:CELGI_RS03030
uniprot id: F8A6Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

593907:CELGI RS01920
gene id: 593907:CELGI_RS01920
uniprot id: F8A4T4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS14810
gene id: 593907:CELGI_RS14810
uniprot id: F8A6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

593907:CELGI RS04700
gene id: 593907:CELGI_RS04700
uniprot id: F8A024
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

593907:CELGI RS03170
gene id: 593907:CELGI_RS03170
uniprot id: F8A6T5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

593907:CELGI RS08080
gene id: 593907:CELGI_RS08080
uniprot id: F8A509
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

593907:CELGI RS10035
gene id: 593907:CELGI_RS10035
uniprot id: F7ZZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

593907:CELGI RS12930
gene id: 593907:CELGI_RS12930
uniprot id: F8A370
names: Similarity
messages: Belongs to the histone deacetylase family.

593907:CELGI RS05250
gene id: 593907:CELGI_RS05250
uniprot id: F8A0T0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

593907:CELGI RS08890
gene id: 593907:CELGI_RS08890
uniprot id: F8A6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

593907:CELGI RS04275
gene id: 593907:CELGI_RS04275
uniprot id: F7ZZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

593907:CELGI RS11060
gene id: 593907:CELGI_RS11060
uniprot id: F8A0K7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

593907:CELGI RS10945
gene id: 593907:CELGI_RS10945
uniprot id: F8A0A8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

593907:CELGI RS08955
gene id: 593907:CELGI_RS08955
uniprot id: F8A6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

593907:CELGI RS07660
gene id: 593907:CELGI_RS07660
uniprot id: F8A4C9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

593907:CELGI RS10575
gene id: 593907:CELGI_RS10575
uniprot id: F7ZZV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

593907:CELGI RS03745
gene id: 593907:CELGI_RS03745
uniprot id: F7ZYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

593907:CELGI RS02460
gene id: 593907:CELGI_RS02460
uniprot id: F8A5Z2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

593907:CELGI RS10320
gene id: 593907:CELGI_RS10320
uniprot id: F7ZZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

593907:CELGI RS03585
gene id: 593907:CELGI_RS03585
uniprot id: F7ZYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS11345
gene id: 593907:CELGI_RS11345
uniprot id: F8A0R1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

593907:CELGI RS07000
gene id: 593907:CELGI_RS07000
uniprot id: F8A345
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

593907:CELGI RS05010
gene id: 593907:CELGI_RS05010
uniprot id: F8A0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

593907:CELGI RS09250
gene id: 593907:CELGI_RS09250
uniprot id: F8A6Y8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

593907:CELGI RS12525
gene id: 593907:CELGI_RS12525
uniprot id: F8A2I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS07680
gene id: 593907:CELGI_RS07680
uniprot id: F8A4D3
names: Similarity
messages: Belongs to the TelA family.

593907:CELGI RS13510
gene id: 593907:CELGI_RS13510
uniprot id: F8A3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 62 family.
messages: Involved in the degradation of xylan and is a key enzyme in the complete degradation of the plant cell wall. It has a specific arabinofuranose-debranching activity on xylan from gramineae. Acts synergistically with the xylanases and binds specifically to xylan. From small arabinoxylo-oligosides (ranging from arabinoxylotriose to arabinoxylohexaose), it liberates arabinose and, after prolonged incubation, the purified enzyme exhibits some xylanolytic activity as well.
messages: Secreted

593907:CELGI RS00195
gene id: 593907:CELGI_RS00195
uniprot id: F8A251
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

593907:CELGI RS16245
gene id: 593907:CELGI_RS16245
uniprot id: F8A5G8
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

593907:CELGI RS04420
gene id: 593907:CELGI_RS04420
uniprot id: F7ZZW8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

593907:CELGI RS04965
gene id: 593907:CELGI_RS04965
uniprot id: F8A0F2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

593907:CELGI RS13250
gene id: 593907:CELGI_RS13250
uniprot id: F8A3D2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS13940
gene id: 593907:CELGI_RS13940
uniprot id: F8A4L2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

593907:CELGI RS15560
gene id: 593907:CELGI_RS15560
uniprot id: F8A7P7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

593907:CELGI RS13895
gene id: 593907:CELGI_RS13895
uniprot id: F8A4K3
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS09690
gene id: 593907:CELGI_RS09690
uniprot id: F8A7M3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

593907:CELGI RS09145
gene id: 593907:CELGI_RS09145
uniprot id: F8A6W8
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

593907:CELGI RS00100
gene id: 593907:CELGI_RS00100
uniprot id: F8A233
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

593907:CELGI RS13780
gene id: 593907:CELGI_RS13780
uniprot id: F8A4I1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

593907:CELGI RS01430
gene id: 593907:CELGI_RS01430
uniprot id: F8A440
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

593907:CELGI RS14295
gene id: 593907:CELGI_RS14295
uniprot id: F8A586
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

593907:CELGI RS12635
gene id: 593907:CELGI_RS12635
uniprot id: F8A2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

593907:CELGI RS03860
gene id: 593907:CELGI_RS03860
uniprot id: F7ZZ12
names: Similarity
messages: Belongs to the WXG100 family.

593907:CELGI RS01775
gene id: 593907:CELGI_RS01775
uniprot id: F8A4Q4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

593907:CELGI RS07335
gene id: 593907:CELGI_RS07335
uniprot id: F8A3R5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

593907:CELGI RS05875
gene id: 593907:CELGI_RS05875
uniprot id: F8A1C8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

593907:CELGI RS12505
gene id: 593907:CELGI_RS12505
uniprot id: F8A2I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

593907:CELGI RS15355
gene id: 593907:CELGI_RS15355
uniprot id: F8A753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS11850
gene id: 593907:CELGI_RS11850
uniprot id: F8A1G5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

593907:CELGI RS11030
gene id: 593907:CELGI_RS11030
uniprot id: F8A0K1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

593907:CELGI RS10660
gene id: 593907:CELGI_RS10660
uniprot id: F8A050
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

593907:CELGI RS10555
gene id: 593907:CELGI_RS10555
uniprot id: F7ZZV0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

593907:CELGI RS04060
gene id: 593907:CELGI_RS04060
uniprot id: F7ZZH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

593907:CELGI RS11890
gene id: 593907:CELGI_RS11890
uniprot id: F8A1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

593907:CELGI RS07200
gene id: 593907:CELGI_RS07200
uniprot id: F8A3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

593907:CELGI RS03765
gene id: 593907:CELGI_RS03765
uniprot id: F7ZYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

593907:CELGI RS02865
gene id: 593907:CELGI_RS02865
uniprot id: F8A6M6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

593907:CELGI RS03795
gene id: 593907:CELGI_RS03795
uniprot id: F7ZZ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

593907:CELGI RS03875
gene id: 593907:CELGI_RS03875
uniprot id: F7ZZ15
names: Similarity
messages: Belongs to the peptidase S8 family.

593907:CELGI RS04720
gene id: 593907:CELGI_RS04720
uniprot id: F8A028
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

593907:CELGI RS12225
gene id: 593907:CELGI_RS12225
uniprot id: F8A1Y0
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

593907:CELGI RS04300
gene id: 593907:CELGI_RS04300
uniprot id: F7ZZL7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

593907:CELGI RS12240
gene id: 593907:CELGI_RS12240
uniprot id: F8A1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS03790
gene id: 593907:CELGI_RS03790
uniprot id: F7ZYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

593907:CELGI RS04840
gene id: 593907:CELGI_RS04840
uniprot id: F8A0C7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

593907:CELGI RS07110
gene id: 593907:CELGI_RS07110
uniprot id: F8A3L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

593907:CELGI RS06895
gene id: 593907:CELGI_RS06895
uniprot id: F8A324
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

593907:CELGI RS01410
gene id: 593907:CELGI_RS01410
uniprot id: F8A436
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS12790
gene id: 593907:CELGI_RS12790
uniprot id: F8A2P0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS13935
gene id: 593907:CELGI_RS13935
uniprot id: F8A4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS13855
gene id: 593907:CELGI_RS13855
uniprot id: F8A4J5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

593907:CELGI RS10695
gene id: 593907:CELGI_RS10695
uniprot id: F8A057
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

593907:CELGI RS08110
gene id: 593907:CELGI_RS08110
uniprot id: F8A515
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

593907:CELGI RS00900
gene id: 593907:CELGI_RS00900
uniprot id: F8A3E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

593907:CELGI RS10015
gene id: 593907:CELGI_RS10015
uniprot id: F7ZZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

593907:CELGI RS08935
gene id: 593907:CELGI_RS08935
uniprot id: F8A6C4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS16075
gene id: 593907:CELGI_RS16075
uniprot id: F7ZZD4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

593907:CELGI RS16225
gene id: 593907:CELGI_RS16225
uniprot id: F8A470
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

593907:CELGI RS06255
gene id: 593907:CELGI_RS06255
uniprot id: F8A1U4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

593907:CELGI RS04805
gene id: 593907:CELGI_RS04805
uniprot id: F8A0C0
names: Similarity
messages: Belongs to the AHA1 family.

593907:CELGI RS02910
gene id: 593907:CELGI_RS02910
uniprot id: F8A6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

593907:CELGI RS09085
gene id: 593907:CELGI_RS09085
uniprot id: F8A6V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

593907:CELGI RS09285
gene id: 593907:CELGI_RS09285
uniprot id: F8A6Z5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

593907:CELGI RS08220
gene id: 593907:CELGI_RS08220
uniprot id: F8A5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

593907:CELGI RS01155
gene id: 593907:CELGI_RS01155
uniprot id: F8A3I7
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS16020
gene id: 593907:CELGI_RS16020
uniprot id: F7ZZC3
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS00330
gene id: 593907:CELGI_RS00330
uniprot id: F8A278
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS02775
gene id: 593907:CELGI_RS02775
uniprot id: F8A653
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

593907:CELGI RS12180
gene id: 593907:CELGI_RS12180
uniprot id: F8A1X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS03730
gene id: 593907:CELGI_RS03730
uniprot id: F7ZYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

593907:CELGI RS04250
gene id: 593907:CELGI_RS04250
uniprot id: F7ZZK7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

593907:CELGI RS04025
gene id: 593907:CELGI_RS04025
uniprot id: F7ZZG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

593907:CELGI RS07980
gene id: 593907:CELGI_RS07980
uniprot id: F8A4Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

593907:CELGI RS08275
gene id: 593907:CELGI_RS08275
uniprot id: F8A5J6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

593907:CELGI RS13710
gene id: 593907:CELGI_RS13710
uniprot id: F8A4G8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

593907:CELGI RS12860
gene id: 593907:CELGI_RS12860
uniprot id: F8A2Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

593907:CELGI RS05595
gene id: 593907:CELGI_RS05595
uniprot id: F8A174
names: Similarity
messages: Belongs to the ABC transporter superfamily.

593907:CELGI RS11665
gene id: 593907:CELGI_RS11665
uniprot id: F8A153
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

593907:CELGI RS10065
gene id: 593907:CELGI_RS10065
uniprot id: F7ZZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

593907:CELGI RS01020
gene id: 593907:CELGI_RS01020
uniprot id: F8A3G4
names: Similarity
messages: Belongs to the AHA1 family.

593907:CELGI RS12640
gene id: 593907:CELGI_RS12640
uniprot id: F8A2L0
names: Similarity
messages: Belongs to the EfeM/EfeO family.

593907:CELGI RS00600
gene id: 593907:CELGI_RS00600
uniprot id: F8A2T4
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS02505
gene id: 593907:CELGI_RS02505
uniprot id: F8A601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

593907:CELGI RS15545
gene id: 593907:CELGI_RS15545
uniprot id: F8A7P4
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

593907:CELGI RS16215
gene id: 593907:CELGI_RS16215
uniprot id: F8A3E0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04225
gene id: 593907:CELGI_RS04225
uniprot id: F7ZZK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

593907:CELGI RS05855
gene id: 593907:CELGI_RS05855
uniprot id: F8A1C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

593907:CELGI RS04055
gene id: 593907:CELGI_RS04055
uniprot id: F7ZZG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

593907:CELGI RS10255
gene id: 593907:CELGI_RS10255
uniprot id: F7ZZP1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

593907:CELGI RS10440
gene id: 593907:CELGI_RS10440
uniprot id: F7ZZS8
names: Similarity
messages: Belongs to the peptidase M16 family.

593907:CELGI RS04635
gene id: 593907:CELGI_RS04635
uniprot id: F8A011
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS00080
gene id: 593907:CELGI_RS00080
uniprot id: F8A229
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

593907:CELGI RS03200
gene id: 593907:CELGI_RS03200
uniprot id: F8A792
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

593907:CELGI RS11535
gene id: 593907:CELGI_RS11535
uniprot id: F8A126
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS16025
gene id: 593907:CELGI_RS16025
uniprot id: F7ZZC4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

593907:CELGI RS08265
gene id: 593907:CELGI_RS08265
uniprot id: F8A5J4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

593907:CELGI RS12465
gene id: 593907:CELGI_RS12465
uniprot id: F8A225
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS15050
gene id: 593907:CELGI_RS15050
uniprot id: F8A6J1
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS07095
gene id: 593907:CELGI_RS07095
uniprot id: F8A3L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

593907:CELGI RS10620
gene id: 593907:CELGI_RS10620
uniprot id: F8A042
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

593907:CELGI RS04795
gene id: 593907:CELGI_RS04795
uniprot id: F8A0B8
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

593907:CELGI RS09175
gene id: 593907:CELGI_RS09175
uniprot id: F8A6X4
names: Similarity
messages: Belongs to the TrpC family.

593907:CELGI RS02395
gene id: 593907:CELGI_RS02395
uniprot id: F8A5H7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

593907:CELGI RS03445
gene id: 593907:CELGI_RS03445
uniprot id: F8A7E0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS14000
gene id: 593907:CELGI_RS14000
uniprot id: F8A4M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS09215
gene id: 593907:CELGI_RS09215
uniprot id: F8A6Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS15640
gene id: 593907:CELGI_RS15640
uniprot id: F8A7R3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

593907:CELGI RS08845
gene id: 593907:CELGI_RS08845
uniprot id: F8A6A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

593907:CELGI RS06995
gene id: 593907:CELGI_RS06995
uniprot id: F8A343
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

593907:CELGI RS07495
gene id: 593907:CELGI_RS07495
uniprot id: F8A494
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

593907:CELGI RS07910
gene id: 593907:CELGI_RS07910
uniprot id: F8A4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

593907:CELGI RS14830
gene id: 593907:CELGI_RS14830
uniprot id: F8A6E7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

593907:CELGI RS07770
gene id: 593907:CELGI_RS07770
uniprot id: F8A4E7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

593907:CELGI RS12700
gene id: 593907:CELGI_RS12700
uniprot id: F8A2M2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS03485
gene id: 593907:CELGI_RS03485
uniprot id: F8A7E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

593907:CELGI RS08595
gene id: 593907:CELGI_RS08595
uniprot id: F8A659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

593907:CELGI RS04695
gene id: 593907:CELGI_RS04695
uniprot id: F8A023
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

593907:CELGI RS09555
gene id: 593907:CELGI_RS09555
uniprot id: F8A7J7
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS06885
gene id: 593907:CELGI_RS06885
uniprot id: F8A322
names: Similarity
messages: Belongs to the CdaR family.

593907:CELGI RS00565
gene id: 593907:CELGI_RS00565
uniprot id: F8A2S7
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS13995
gene id: 593907:CELGI_RS13995
uniprot id: F8A4M3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

593907:CELGI RS08005
gene id: 593907:CELGI_RS08005
uniprot id: F8A4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS03715
gene id: 593907:CELGI_RS03715
uniprot id: F7ZYY4
names: Similarity
messages: Belongs to the isochorismate synthase family.

593907:CELGI RS01980
gene id: 593907:CELGI_RS01980
uniprot id: F8A4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

593907:CELGI RS00940
gene id: 593907:CELGI_RS00940
uniprot id: F8A3F0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

593907:CELGI RS04220
gene id: 593907:CELGI_RS04220
uniprot id: F7ZZK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

593907:CELGI RS04580
gene id: 593907:CELGI_RS04580
uniprot id: F8A000
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

593907:CELGI RS00465
gene id: 593907:CELGI_RS00465
uniprot id: F8A2Q7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

593907:CELGI RS10185
gene id: 593907:CELGI_RS10185
uniprot id: F7ZZA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

593907:CELGI RS10625
gene id: 593907:CELGI_RS10625
uniprot id: F8A043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

593907:CELGI RS09050
gene id: 593907:CELGI_RS09050
uniprot id: F8A6U9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS00405
gene id: 593907:CELGI_RS00405
uniprot id: F8A292
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

593907:CELGI RS10485
gene id: 593907:CELGI_RS10485
uniprot id: F7ZZT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

593907:CELGI RS03720
gene id: 593907:CELGI_RS03720
uniprot id: F7ZYY5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

593907:CELGI RS08880
gene id: 593907:CELGI_RS08880
uniprot id: F8A6B3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

593907:CELGI RS00410
gene id: 593907:CELGI_RS00410
uniprot id: F8A293
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

593907:CELGI RS08100
gene id: 593907:CELGI_RS08100
uniprot id: F8A513
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

593907:CELGI RS05425
gene id: 593907:CELGI_RS05425
uniprot id: F8A0W5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS08035
gene id: 593907:CELGI_RS08035
uniprot id: F8A500
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS13950
gene id: 593907:CELGI_RS13950
uniprot id: F8A4L4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS12735
gene id: 593907:CELGI_RS12735
uniprot id: F8A2M9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

593907:CELGI RS03040
gene id: 593907:CELGI_RS03040
uniprot id: F8A6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

593907:CELGI RS04530
gene id: 593907:CELGI_RS04530
uniprot id: F7ZZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

593907:CELGI RS07535
gene id: 593907:CELGI_RS07535
uniprot id: F8A4A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

593907:CELGI RS06345
gene id: 593907:CELGI_RS06345
uniprot id: F8A2B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

593907:CELGI RS15210
gene id: 593907:CELGI_RS15210
uniprot id: F8A724
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS01785
gene id: 593907:CELGI_RS01785
uniprot id: F8A4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

593907:CELGI RS07080
gene id: 593907:CELGI_RS07080
uniprot id: F8A3L3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

593907:CELGI RS09615
gene id: 593907:CELGI_RS09615
uniprot id: F8A7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

593907:CELGI RS06265
gene id: 593907:CELGI_RS06265
uniprot id: F8A1U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

593907:CELGI RS09595
gene id: 593907:CELGI_RS09595
uniprot id: F8A7K4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

593907:CELGI RS09135
gene id: 593907:CELGI_RS09135
uniprot id: F8A6W6
names: Similarity
messages: Belongs to the GSP E family.

593907:CELGI RS01835
gene id: 593907:CELGI_RS01835
uniprot id: F8A4R7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

593907:CELGI RS04175
gene id: 593907:CELGI_RS04175
uniprot id: F7ZZJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

593907:CELGI RS10205
gene id: 593907:CELGI_RS10205
uniprot id: F7ZZN1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04755
gene id: 593907:CELGI_RS04755
uniprot id: F8A035
names: Similarity
messages: Belongs to the UPF0235 family.

593907:CELGI RS04535
gene id: 593907:CELGI_RS04535
uniprot id: F7ZZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

593907:CELGI RS05545
gene id: 593907:CELGI_RS05545
uniprot id: F8A164
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

593907:CELGI RS02305
gene id: 593907:CELGI_RS02305
uniprot id: F8A5G0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

593907:CELGI RS05965
gene id: 593907:CELGI_RS05965
uniprot id: F8A1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

593907:CELGI RS03965
gene id: 593907:CELGI_RS03965
uniprot id: F7ZZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

593907:CELGI RS14235
gene id: 593907:CELGI_RS14235
uniprot id: F8A573
names: Similarity
messages: Belongs to the serpin family.

593907:CELGI RS14660
gene id: 593907:CELGI_RS14660
uniprot id: F8A5W0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

593907:CELGI RS08975
gene id: 593907:CELGI_RS08975
uniprot id: F8A6D2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

593907:CELGI RS04185
gene id: 593907:CELGI_RS04185
uniprot id: F7ZZJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

593907:CELGI RS03680
gene id: 593907:CELGI_RS03680
uniprot id: F7ZYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

593907:CELGI RS11415
gene id: 593907:CELGI_RS11415
uniprot id: F8A102
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

593907:CELGI RS13320
gene id: 593907:CELGI_RS13320
uniprot id: F8A3U7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

593907:CELGI RS00035
gene id: 593907:CELGI_RS00035
uniprot id: F8A1M0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

593907:CELGI RS02410
gene id: 593907:CELGI_RS02410
uniprot id: F8A5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

593907:CELGI RS09210
gene id: 593907:CELGI_RS09210
uniprot id: F8A6Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

593907:CELGI RS04215
gene id: 593907:CELGI_RS04215
uniprot id: F7ZZK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

593907:CELGI RS00455
gene id: 593907:CELGI_RS00455
uniprot id: F8A2A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

593907:CELGI RS07075
gene id: 593907:CELGI_RS07075
uniprot id: F8A3L2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

593907:CELGI RS15635
gene id: 593907:CELGI_RS15635
uniprot id: F8A7R2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

593907:CELGI RS11380
gene id: 593907:CELGI_RS11380
uniprot id: F8A0Z5
names: Similarity
messages: Belongs to the HSP15 family.

593907:CELGI RS12010
gene id: 593907:CELGI_RS12010
uniprot id: F8A1J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

593907:CELGI RS09520
gene id: 593907:CELGI_RS09520
uniprot id: F8A7J0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

593907:CELGI RS06455
gene id: 593907:CELGI_RS06455
uniprot id: F8A2D4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

593907:CELGI RS10680
gene id: 593907:CELGI_RS10680
uniprot id: F8A054
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

593907:CELGI RS03165
gene id: 593907:CELGI_RS03165
uniprot id: F8A6T4
names: Cofactor
messages: Can also use Mn(2+) ion.

593907:CELGI RS02335
gene id: 593907:CELGI_RS02335
uniprot id: F8A5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS11715
gene id: 593907:CELGI_RS11715
uniprot id: F8A163
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12885
gene id: 593907:CELGI_RS12885
uniprot id: F8A360
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

593907:CELGI RS15235
gene id: 593907:CELGI_RS15235
uniprot id: F8A729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS04010
gene id: 593907:CELGI_RS04010
uniprot id: F7ZZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

593907:CELGI RS10400
gene id: 593907:CELGI_RS10400
uniprot id: F7ZZS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

593907:CELGI RS10075
gene id: 593907:CELGI_RS10075
uniprot id: F7ZZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

593907:CELGI RS08395
gene id: 593907:CELGI_RS08395
uniprot id: F8A5L9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

593907:CELGI RS16420
gene id: 593907:CELGI_RS16420
uniprot id: F8A2Z3
names: Similarity
messages: Belongs to the ParB family.

593907:CELGI RS11275
gene id: 593907:CELGI_RS11275
uniprot id: F8A0P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

593907:CELGI RS05690
gene id: 593907:CELGI_RS05690
uniprot id: F8A193
names: Similarity
messages: Belongs to the phosphohexose mutase family.

593907:CELGI RS15240
gene id: 593907:CELGI_RS15240
uniprot id: F8A730
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

593907:CELGI RS04260
gene id: 593907:CELGI_RS04260
uniprot id: F7ZZK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

593907:CELGI RS07120
gene id: 593907:CELGI_RS07120
uniprot id: F8A3M1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS13860
gene id: 593907:CELGI_RS13860
uniprot id: F8A4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

593907:CELGI RS01745
gene id: 593907:CELGI_RS01745
uniprot id: F8A4P8
names: Similarity
messages: Belongs to the UPF0045 family.

593907:CELGI RS11090
gene id: 593907:CELGI_RS11090
uniprot id: F8A0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS10595
gene id: 593907:CELGI_RS10595
uniprot id: F8A037
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

593907:CELGI RS01810
gene id: 593907:CELGI_RS01810
uniprot id: F8A4R1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS01365
gene id: 593907:CELGI_RS01365
uniprot id: F8A428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

593907:CELGI RS08010
gene id: 593907:CELGI_RS08010
uniprot id: F8A4Z5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

593907:CELGI RS10825
gene id: 593907:CELGI_RS10825
uniprot id: F8A083
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS13885
gene id: 593907:CELGI_RS13885
uniprot id: F8A4K1
names: Similarity
messages: Belongs to the GARS family.

593907:CELGI RS03450
gene id: 593907:CELGI_RS03450
uniprot id: F8A7E1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

593907:CELGI RS09740
gene id: 593907:CELGI_RS09740
uniprot id: F8A7N3
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS05205
gene id: 593907:CELGI_RS05205
uniprot id: F8A0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

593907:CELGI RS12515
gene id: 593907:CELGI_RS12515
uniprot id: F8A2I6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

593907:CELGI RS00310
gene id: 593907:CELGI_RS00310
uniprot id: F8A274
names: Similarity
messages: Belongs to the CsoR family.

593907:CELGI RS03520
gene id: 593907:CELGI_RS03520
uniprot id: F8A7F5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

593907:CELGI RS03375
gene id: 593907:CELGI_RS03375
uniprot id: F8A7C6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

593907:CELGI RS06015
gene id: 593907:CELGI_RS06015
uniprot id: F8A1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

593907:CELGI RS02940
gene id: 593907:CELGI_RS02940
uniprot id: F8A6P0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

593907:CELGI RS13335
gene id: 593907:CELGI_RS13335
uniprot id: F8A3V0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS03710
gene id: 593907:CELGI_RS03710
uniprot id: F7ZYY3
names: Similarity
messages: Belongs to the peptidase S1C family.

593907:CELGI RS05415
gene id: 593907:CELGI_RS05415
uniprot id: F8A0W3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

593907:CELGI RS03650
gene id: 593907:CELGI_RS03650
uniprot id: F7ZYX0
names: Similarity
messages: Belongs to the citrate synthase family.

593907:CELGI RS13305
gene id: 593907:CELGI_RS13305
uniprot id: F8A3U4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

593907:CELGI RS01860
gene id: 593907:CELGI_RS01860
uniprot id: F8A4S2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

593907:CELGI RS11690
gene id: 593907:CELGI_RS11690
uniprot id: F8A158
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

593907:CELGI RS05865
gene id: 593907:CELGI_RS05865
uniprot id: F8A1C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

593907:CELGI RS16145
gene id: 593907:CELGI_RS16145
uniprot id: F7ZZE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

593907:CELGI RS03800
gene id: 593907:CELGI_RS03800
uniprot id: F7ZZ01
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

593907:CELGI RS11920
gene id: 593907:CELGI_RS11920
uniprot id: F8A1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS06950
gene id: 593907:CELGI_RS06950
uniprot id: F8A334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS09255
gene id: 593907:CELGI_RS09255
uniprot id: F8A6Y9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

593907:CELGI RS13555
gene id: 593907:CELGI_RS13555
uniprot id: F8A3Z6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

593907:CELGI RS08815
gene id: 593907:CELGI_RS08815
uniprot id: F8A6A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

593907:CELGI RS06865
gene id: 593907:CELGI_RS06865
uniprot id: F8A318
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

593907:CELGI RS04515
gene id: 593907:CELGI_RS04515
uniprot id: F7ZZY7
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

593907:CELGI RS07420
gene id: 593907:CELGI_RS07420
uniprot id: F8A3T2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

593907:CELGI RS03910
gene id: 593907:CELGI_RS03910
uniprot id: F7ZZ22
names: Similarity
messages: Belongs to the UPF0234 family.

593907:CELGI RS12230
gene id: 593907:CELGI_RS12230
uniprot id: F8A1Y1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

593907:CELGI RS08990
gene id: 593907:CELGI_RS08990
uniprot id: F8A6D5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

593907:CELGI RS07175
gene id: 593907:CELGI_RS07175
uniprot id: F8A3N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

593907:CELGI RS10455
gene id: 593907:CELGI_RS10455
uniprot id: F7ZZT1
names: Similarity
messages: Belongs to the ribF family.

593907:CELGI RS07050
gene id: 593907:CELGI_RS07050
uniprot id: F8A355
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

593907:CELGI RS10580
gene id: 593907:CELGI_RS10580
uniprot id: F7ZZV5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

593907:CELGI RS06285
gene id: 593907:CELGI_RS06285
uniprot id: F8A1V0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS06420
gene id: 593907:CELGI_RS06420
uniprot id: F8A2C7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

593907:CELGI RS01225
gene id: 593907:CELGI_RS01225
uniprot id: F8A3K2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS14140
gene id: 593907:CELGI_RS14140
uniprot id: F8A554
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

593907:CELGI RS05210
gene id: 593907:CELGI_RS05210
uniprot id: F8A0S2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

593907:CELGI RS12645
gene id: 593907:CELGI_RS12645
uniprot id: F8A2L1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

593907:CELGI RS02400
gene id: 593907:CELGI_RS02400
uniprot id: F8A5H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

593907:CELGI RS05535
gene id: 593907:CELGI_RS05535
uniprot id: F8A0Y7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

593907:CELGI RS01455
gene id: 593907:CELGI_RS01455
uniprot id: F8A445
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

593907:CELGI RS04210
gene id: 593907:CELGI_RS04210
uniprot id: F7ZZJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

593907:CELGI RS06270
gene id: 593907:CELGI_RS06270
uniprot id: F8A1U7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

593907:CELGI RS11445
gene id: 593907:CELGI_RS11445
uniprot id: F8A108
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

593907:CELGI RS02965
gene id: 593907:CELGI_RS02965
uniprot id: F8A6P5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

593907:CELGI RS09625
gene id: 593907:CELGI_RS09625
uniprot id: F8A7L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

593907:CELGI RS04910
gene id: 593907:CELGI_RS04910
uniprot id: F8A0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

593907:CELGI RS06840
gene id: 593907:CELGI_RS06840
uniprot id: F8A313
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

593907:CELGI RS12780
gene id: 593907:CELGI_RS12780
uniprot id: F8A2N8
names: Similarity
messages: Belongs to the peptidase S1C family.

593907:CELGI RS09845
gene id: 593907:CELGI_RS09845
uniprot id: F7ZZ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

593907:CELGI RS15865
gene id: 593907:CELGI_RS15865
uniprot id: F8A7V7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

593907:CELGI RS01260
gene id: 593907:CELGI_RS01260
uniprot id: F8A410
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

593907:CELGI RS14530
gene id: 593907:CELGI_RS14530
uniprot id: F8A5T5
names: Similarity
messages: Belongs to the AAA ATPase family.

593907:CELGI RS12035
gene id: 593907:CELGI_RS12035
uniprot id: F8A1K2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS05930
gene id: 593907:CELGI_RS05930
uniprot id: F8A1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

593907:CELGI RS09765
gene id: 593907:CELGI_RS09765
uniprot id: F8A7N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS09715
gene id: 593907:CELGI_RS09715
uniprot id: F8A7M8
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS07585
gene id: 593907:CELGI_RS07585
uniprot id: F8A4B3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

593907:CELGI RS07995
gene id: 593907:CELGI_RS07995
uniprot id: F8A4Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

593907:CELGI RS02195
gene id: 593907:CELGI_RS02195
uniprot id: F8A5D8
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS06280
gene id: 593907:CELGI_RS06280
uniprot id: F8A1U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

593907:CELGI RS07190
gene id: 593907:CELGI_RS07190
uniprot id: F8A3N6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

593907:CELGI RS07930
gene id: 593907:CELGI_RS07930
uniprot id: F8A4X9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

593907:CELGI RS02380
gene id: 593907:CELGI_RS02380
uniprot id: F8A5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

593907:CELGI RS08850
gene id: 593907:CELGI_RS08850
uniprot id: F8A6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

593907:CELGI RS10140
gene id: 593907:CELGI_RS10140
uniprot id: F7ZZ96
names: Subcellular Location Annotation
messages: Cytoplasm

593907:CELGI RS15875
gene id: 593907:CELGI_RS15875
uniprot id: F8A7V9
names: Similarity
messages: Belongs to the cytochrome P450 family.

593907:CELGI RS00110
gene id: 593907:CELGI_RS00110
uniprot id: F8A235
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

593907:CELGI RS00005
gene id: 593907:CELGI_RS00005
uniprot id: F8A1L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

593907:CELGI RS09985
gene id: 593907:CELGI_RS09985
uniprot id: F7ZZ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

593907:CELGI RS06650
gene id: 593907:CELGI_RS06650
uniprot id: F8A2H3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

593907:CELGI RS11170
gene id: 593907:CELGI_RS11170
uniprot id: F8A0M9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

593907:CELGI RS07975
gene id: 593907:CELGI_RS07975
uniprot id: F8A4Y8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

593907:CELGI RS06440
gene id: 593907:CELGI_RS06440
uniprot id: F8A2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS11745
gene id: 593907:CELGI_RS11745
uniprot id: F8A1E3
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS05935
gene id: 593907:CELGI_RS05935
uniprot id: F8A1N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

593907:CELGI RS06845
gene id: 593907:CELGI_RS06845
uniprot id: F8A314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS05375
gene id: 593907:CELGI_RS05375
uniprot id: F8A0V5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

593907:CELGI RS06460
gene id: 593907:CELGI_RS06460
uniprot id: F8A2D5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

593907:CELGI RS15625
gene id: 593907:CELGI_RS15625
uniprot id: F8A7R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04940
gene id: 593907:CELGI_RS04940
uniprot id: F8A0E7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

593907:CELGI RS14755
gene id: 593907:CELGI_RS14755
uniprot id: F8A5Y0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

593907:CELGI RS04380
gene id: 593907:CELGI_RS04380
uniprot id: F7ZZW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

593907:CELGI RS00015
gene id: 593907:CELGI_RS00015
uniprot id: F8A1L6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

593907:CELGI RS04460
gene id: 593907:CELGI_RS04460
uniprot id: F7ZZX6
names: Similarity
messages: Belongs to the AHA1 family.

593907:CELGI RS12350
gene id: 593907:CELGI_RS12350
uniprot id: F8A202
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

593907:CELGI RS09635
gene id: 593907:CELGI_RS09635
uniprot id: F8A7L2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS00315
gene id: 593907:CELGI_RS00315
uniprot id: F8A275
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

593907:CELGI RS11940
gene id: 593907:CELGI_RS11940
uniprot id: F8A1I2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS16030
gene id: 593907:CELGI_RS16030
uniprot id: F7ZZC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

593907:CELGI RS08070
gene id: 593907:CELGI_RS08070
uniprot id: F8A507
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12445
gene id: 593907:CELGI_RS12445
uniprot id: F8A221
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

593907:CELGI RS06185
gene id: 593907:CELGI_RS06185
uniprot id: F8A1T0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

593907:CELGI RS13725
gene id: 593907:CELGI_RS13725
uniprot id: F8A4H1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

593907:CELGI RS00030
gene id: 593907:CELGI_RS00030
uniprot id: F8A1L9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

593907:CELGI RS12665
gene id: 593907:CELGI_RS12665
uniprot id: F8A2L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

593907:CELGI RS10045
gene id: 593907:CELGI_RS10045
uniprot id: F7ZZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

593907:CELGI RS10495
gene id: 593907:CELGI_RS10495
uniprot id: F7ZZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

593907:CELGI RS10215
gene id: 593907:CELGI_RS10215
uniprot id: F7ZZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

593907:CELGI RS13115
gene id: 593907:CELGI_RS13115
uniprot id: F8A3A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

593907:CELGI RS12960
gene id: 593907:CELGI_RS12960
uniprot id: F8A376
names: Similarity
messages: Belongs to the glycosyl hydrolase.

593907:CELGI RS04015
gene id: 593907:CELGI_RS04015
uniprot id: F7ZZG1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

593907:CELGI RS11640
gene id: 593907:CELGI_RS11640
uniprot id: F8A148
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

593907:CELGI RS05970
gene id: 593907:CELGI_RS05970
uniprot id: F8A1N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

593907:CELGI RS12905
gene id: 593907:CELGI_RS12905
uniprot id: F8A364
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

593907:CELGI RS11720
gene id: 593907:CELGI_RS11720
uniprot id: F8A1D8
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS15350
gene id: 593907:CELGI_RS15350
uniprot id: F8A752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS17630
gene id: 593907:CELGI_RS17630
uniprot id: F8A211
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

593907:CELGI RS08105
gene id: 593907:CELGI_RS08105
uniprot id: F8A514
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

593907:CELGI RS03270
gene id: 593907:CELGI_RS03270
uniprot id: F8A7A5
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS15730
gene id: 593907:CELGI_RS15730
uniprot id: F8A7T0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS13040
gene id: 593907:CELGI_RS13040
uniprot id: F8A392
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

593907:CELGI RS07435
gene id: 593907:CELGI_RS07435
uniprot id: F8A3T5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

593907:CELGI RS10235
gene id: 593907:CELGI_RS10235
uniprot id: F7ZZN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04830
gene id: 593907:CELGI_RS04830
uniprot id: F8A0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

593907:CELGI RS00190
gene id: 593907:CELGI_RS00190
uniprot id: F8A250
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

593907:CELGI RS10280
gene id: 593907:CELGI_RS10280
uniprot id: F7ZZP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS00925
gene id: 593907:CELGI_RS00925
uniprot id: F8A3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS06165
gene id: 593907:CELGI_RS06165
uniprot id: F8A1S6
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS08210
gene id: 593907:CELGI_RS08210
uniprot id: F8A5I3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

593907:CELGI RS12830
gene id: 593907:CELGI_RS12830
uniprot id: F8A2P9
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS11670
gene id: 593907:CELGI_RS11670
uniprot id: F8A154
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS07960
gene id: 593907:CELGI_RS07960
uniprot id: F8A4Y5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS09245
gene id: 593907:CELGI_RS09245
uniprot id: F8A6Y7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

593907:CELGI RS03970
gene id: 593907:CELGI_RS03970
uniprot id: F7ZZF3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

593907:CELGI RS13130
gene id: 593907:CELGI_RS13130
uniprot id: F8A3A8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS15370
gene id: 593907:CELGI_RS15370
uniprot id: F8A756
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

593907:CELGI RS03405
gene id: 593907:CELGI_RS03405
uniprot id: F8A7D2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS11100
gene id: 593907:CELGI_RS11100
uniprot id: F8A0L5
names: Similarity
messages: Belongs to the peptidase M1 family.

593907:CELGI RS05135
gene id: 593907:CELGI_RS05135
uniprot id: F8A0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

593907:CELGI RS16100
gene id: 593907:CELGI_RS16100
uniprot id: F7ZZD9
names: Similarity
messages: Belongs to the thioredoxin family.

593907:CELGI RS13425
gene id: 593907:CELGI_RS13425
uniprot id: F8A3X0
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

593907:CELGI RS10600
gene id: 593907:CELGI_RS10600
uniprot id: F8A038
names: Similarity
messages: Belongs to the DprA/Smf family.

593907:CELGI RS09925
gene id: 593907:CELGI_RS09925
uniprot id: F7ZZ53
names: Similarity
messages: Belongs to the catalase family.

593907:CELGI RS10385
gene id: 593907:CELGI_RS10385
uniprot id: F7ZZR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

593907:CELGI RS02260
gene id: 593907:CELGI_RS02260
uniprot id: F8A5F1
names: Similarity
messages: Belongs to the bacterial flagellin family.

593907:CELGI RS12530
gene id: 593907:CELGI_RS12530
uniprot id: F8A2I9
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS10380
gene id: 593907:CELGI_RS10380
uniprot id: F7ZZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

593907:CELGI RS07310
gene id: 593907:CELGI_RS07310
uniprot id: F8A3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

593907:CELGI RS04655
gene id: 593907:CELGI_RS04655
uniprot id: F8A015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

593907:CELGI RS08095
gene id: 593907:CELGI_RS08095
uniprot id: F8A512
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

593907:CELGI RS11040
gene id: 593907:CELGI_RS11040
uniprot id: F8A0K3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

593907:CELGI RS04400
gene id: 593907:CELGI_RS04400
uniprot id: F7ZZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

593907:CELGI RS08475
gene id: 593907:CELGI_RS08475
uniprot id: F8A5N6
names: Similarity
messages: Belongs to the pirin family.

593907:CELGI RS03205
gene id: 593907:CELGI_RS03205
uniprot id: F8A793
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

593907:CELGI RS16095
gene id: 593907:CELGI_RS16095
uniprot id: F7ZZD8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

593907:CELGI RS09850
gene id: 593907:CELGI_RS09850
uniprot id: F7ZZ39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

593907:CELGI RS12125
gene id: 593907:CELGI_RS12125
uniprot id: F8A1W0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

593907:CELGI RS16250
gene id: 593907:CELGI_RS16250
uniprot id: F8A6S2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the N-terminal section; belongs to the MobA family.

593907:CELGI RS08995
gene id: 593907:CELGI_RS08995
uniprot id: F8A6T8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

593907:CELGI RS08515
gene id: 593907:CELGI_RS08515
uniprot id: F8A5P4
names: Similarity
messages: Belongs to the Dps family.

593907:CELGI RS10030
gene id: 593907:CELGI_RS10030
uniprot id: F7ZZ74
names: Similarity
messages: Belongs to the YggT family.

593907:CELGI RS15310
gene id: 593907:CELGI_RS15310
uniprot id: F8A744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS11390
gene id: 593907:CELGI_RS11390
uniprot id: F8A0Z7
names: Similarity
messages: Belongs to the YciI family.

593907:CELGI RS08895
gene id: 593907:CELGI_RS08895
uniprot id: F8A6B6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

593907:CELGI RS07060
gene id: 593907:CELGI_RS07060
uniprot id: F8A3K9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS08295
gene id: 593907:CELGI_RS08295
uniprot id: F8A5K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

593907:CELGI RS14650
gene id: 593907:CELGI_RS14650
uniprot id: F8A5V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

593907:CELGI RS11480
gene id: 593907:CELGI_RS11480
uniprot id: F8A115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

593907:CELGI RS08225
gene id: 593907:CELGI_RS08225
uniprot id: F8A5I6
names: Similarity
messages: Belongs to the YciI family.

593907:CELGI RS15680
gene id: 593907:CELGI_RS15680
uniprot id: F8A7S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

593907:CELGI RS15575
gene id: 593907:CELGI_RS15575
uniprot id: F8A7Q0
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

593907:CELGI RS01015
gene id: 593907:CELGI_RS01015
uniprot id: F8A3G3
names: Similarity
messages: Belongs to the UPF0225 family.

593907:CELGI RS04570
gene id: 593907:CELGI_RS04570
uniprot id: F7ZZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

593907:CELGI RS01555
gene id: 593907:CELGI_RS01555
uniprot id: F8A465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS11190
gene id: 593907:CELGI_RS11190
uniprot id: F8A0N3
names: Similarity
messages: Belongs to the AHA1 family.

593907:CELGI RS04330
gene id: 593907:CELGI_RS04330
uniprot id: F7ZZM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS09025
gene id: 593907:CELGI_RS09025
uniprot id: F8A6U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

593907:CELGI RS04855
gene id: 593907:CELGI_RS04855
uniprot id: F8A0D0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS09905
gene id: 593907:CELGI_RS09905
uniprot id: F7ZZ50
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

593907:CELGI RS02960
gene id: 593907:CELGI_RS02960
uniprot id: F8A6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

593907:CELGI RS07965
gene id: 593907:CELGI_RS07965
uniprot id: F8A4Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

593907:CELGI RS08970
gene id: 593907:CELGI_RS08970
uniprot id: F8A6D1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS01495
gene id: 593907:CELGI_RS01495
uniprot id: F8A453
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

593907:CELGI RS06150
gene id: 593907:CELGI_RS06150
uniprot id: F8A1S3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS03780
gene id: 593907:CELGI_RS03780
uniprot id: F7ZYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

593907:CELGI RS17575
gene id: 593907:CELGI_RS17575
uniprot id: F8A5L3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

593907:CELGI RS03370
gene id: 593907:CELGI_RS03370
uniprot id: F8A7C5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

593907:CELGI RS15710
gene id: 593907:CELGI_RS15710
uniprot id: F8A7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

593907:CELGI RS11475
gene id: 593907:CELGI_RS11475
uniprot id: F8A114
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

593907:CELGI RS10705
gene id: 593907:CELGI_RS10705
uniprot id: F8A059
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS07605
gene id: 593907:CELGI_RS07605
uniprot id: F8A4B7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

593907:CELGI RS11255
gene id: 593907:CELGI_RS11255
uniprot id: F8A0P2
names: Similarity
messages: Belongs to the thioredoxin family.

593907:CELGI RS06915
gene id: 593907:CELGI_RS06915
uniprot id: F8A328
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

593907:CELGI RS12410
gene id: 593907:CELGI_RS12410
uniprot id: F8A214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

593907:CELGI RS04415
gene id: 593907:CELGI_RS04415
uniprot id: F7ZZW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04080
gene id: 593907:CELGI_RS04080
uniprot id: F7ZZH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

593907:CELGI RS04190
gene id: 593907:CELGI_RS04190
uniprot id: F7ZZJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

593907:CELGI RS07220
gene id: 593907:CELGI_RS07220
uniprot id: F8A3P2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04450
gene id: 593907:CELGI_RS04450
uniprot id: F7ZZX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

593907:CELGI RS07920
gene id: 593907:CELGI_RS07920
uniprot id: F8A4X7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS05195
gene id: 593907:CELGI_RS05195
uniprot id: F8A0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

593907:CELGI RS07385
gene id: 593907:CELGI_RS07385
uniprot id: F8A3S5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

593907:CELGI RS10125
gene id: 593907:CELGI_RS10125
uniprot id: F7ZZ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

593907:CELGI RS14485
gene id: 593907:CELGI_RS14485
uniprot id: F8A5S6
names: Subcellular Location Annotation
messages: Cytoplasm

593907:CELGI RS12580
gene id: 593907:CELGI_RS12580
uniprot id: F8A2J8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

593907:CELGI RS00450
gene id: 593907:CELGI_RS00450
uniprot id: F8A2A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

593907:CELGI RS01290
gene id: 593907:CELGI_RS01290
uniprot id: F8A415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

593907:CELGI RS05430
gene id: 593907:CELGI_RS05430
uniprot id: F8A0W6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

593907:CELGI RS12185
gene id: 593907:CELGI_RS12185
uniprot id: F8A1X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

593907:CELGI RS08150
gene id: 593907:CELGI_RS08150
uniprot id: F8A523
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS10345
gene id: 593907:CELGI_RS10345
uniprot id: F7ZZQ9
names: Similarity
messages: Belongs to the FPG family.

593907:CELGI RS00870
gene id: 593907:CELGI_RS00870
uniprot id: F8A3D6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

593907:CELGI RS04335
gene id: 593907:CELGI_RS04335
uniprot id: F7ZZM4
names: Subcellular Location Annotation
messages: Cell membrane

593907:CELGI RS03210
gene id: 593907:CELGI_RS03210
uniprot id: F8A794
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

593907:CELGI RS09835
gene id: 593907:CELGI_RS09835
uniprot id: F7ZZ36
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

593907:CELGI RS02225
gene id: 593907:CELGI_RS02225
uniprot id: F8A5E4
names: Subcellular Location Annotation
messages: Cytoplasm

593907:CELGI RS11150
gene id: 593907:CELGI_RS11150
uniprot id: F8A0M5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

593907:CELGI RS01790
gene id: 593907:CELGI_RS01790
uniprot id: F8A4Q7
names: Similarity
messages: Belongs to the peptidase S13 family.

593907:CELGI RS12480
gene id: 593907:CELGI_RS12480
uniprot id: F8A228
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

593907:CELGI RS12935
gene id: 593907:CELGI_RS12935
uniprot id: F8A371
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12995
gene id: 593907:CELGI_RS12995
uniprot id: F8A383
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

593907:CELGI RS12120
gene id: 593907:CELGI_RS12120
uniprot id: F8A1V9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

593907:CELGI RS05550
gene id: 593907:CELGI_RS05550
uniprot id: F8A165
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

593907:CELGI RS11560
gene id: 593907:CELGI_RS11560
uniprot id: F8A131
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

593907:CELGI RS12760
gene id: 593907:CELGI_RS12760
uniprot id: F8A2N4
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS14460
gene id: 593907:CELGI_RS14460
uniprot id: F8A5S1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

593907:CELGI RS09820
gene id: 593907:CELGI_RS09820
uniprot id: F7ZZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

593907:CELGI RS13100
gene id: 593907:CELGI_RS13100
uniprot id: F8A3A2
names: Similarity
messages: Belongs to the DNA photolyase family.

593907:CELGI RS02520
gene id: 593907:CELGI_RS02520
uniprot id: F8A604
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS02390
gene id: 593907:CELGI_RS02390
uniprot id: F8A5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

593907:CELGI RS09890
gene id: 593907:CELGI_RS09890
uniprot id: F7ZZ47
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

593907:CELGI RS04240
gene id: 593907:CELGI_RS04240
uniprot id: F7ZZK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

593907:CELGI RS08945
gene id: 593907:CELGI_RS08945
uniprot id: F8A6C6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS06085
gene id: 593907:CELGI_RS06085
uniprot id: F8A1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS10715
gene id: 593907:CELGI_RS10715
uniprot id: F8A061
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

593907:CELGI RS01575
gene id: 593907:CELGI_RS01575
uniprot id: F8A469
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

593907:CELGI RS10395
gene id: 593907:CELGI_RS10395
uniprot id: F7ZZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS03465
gene id: 593907:CELGI_RS03465
uniprot id: F8A7E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS04550
gene id: 593907:CELGI_RS04550
uniprot id: F7ZZZ4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

593907:CELGI RS03415
gene id: 593907:CELGI_RS03415
uniprot id: F8A7D4
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS13270
gene id: 593907:CELGI_RS13270
uniprot id: F8A3T7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

593907:CELGI RS02330
gene id: 593907:CELGI_RS02330
uniprot id: F8A5G5
names: Subcellular Location Annotation
messages: Cytoplasm

593907:CELGI RS12440
gene id: 593907:CELGI_RS12440
uniprot id: F8A220
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

593907:CELGI RS08530
gene id: 593907:CELGI_RS08530
uniprot id: F8A5P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

593907:CELGI RS13900
gene id: 593907:CELGI_RS13900
uniprot id: F8A4K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

593907:CELGI RS05700
gene id: 593907:CELGI_RS05700
uniprot id: F8A195
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS07675
gene id: 593907:CELGI_RS07675
uniprot id: F8A4D2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS10930
gene id: 593907:CELGI_RS10930
uniprot id: F8A0A5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

593907:CELGI RS03075
gene id: 593907:CELGI_RS03075
uniprot id: F8A6R6
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

593907:CELGI RS08075
gene id: 593907:CELGI_RS08075
uniprot id: F8A508
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

593907:CELGI RS04490
gene id: 593907:CELGI_RS04490
uniprot id: F7ZZY2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

593907:CELGI RS01590
gene id: 593907:CELGI_RS01590
uniprot id: F8A472
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

593907:CELGI RS01360
gene id: 593907:CELGI_RS01360
uniprot id: F8A427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

593907:CELGI RS14515
gene id: 593907:CELGI_RS14515
uniprot id: F8A5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

593907:CELGI RS10740
gene id: 593907:CELGI_RS10740
uniprot id: F8A066
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

593907:CELGI RS15750
gene id: 593907:CELGI_RS15750
uniprot id: F8A7T5
names: Similarity
messages: Belongs to the YciI family.

593907:CELGI RS03835
gene id: 593907:CELGI_RS03835
uniprot id: F7ZZ12
names: Similarity
messages: Belongs to the WXG100 family.

593907:CELGI RS11970
gene id: 593907:CELGI_RS11970
uniprot id: F8A1I8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

593907:CELGI RS03045
gene id: 593907:CELGI_RS03045
uniprot id: F8A6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

593907:CELGI RS08920
gene id: 593907:CELGI_RS08920
uniprot id: F8A6C1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

593907:CELGI RS08000
gene id: 593907:CELGI_RS08000
uniprot id: F8A4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

593907:CELGI RS08560
gene id: 593907:CELGI_RS08560
uniprot id: F8A5Q3
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

593907:CELGI RS15715
gene id: 593907:CELGI_RS15715
uniprot id: F8A7S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

593907:CELGI RS02205
gene id: 593907:CELGI_RS02205
uniprot id: F8A5E0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

593907:CELGI RS02070
gene id: 593907:CELGI_RS02070
uniprot id: F8A5B4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

593907:CELGI RS04090
gene id: 593907:CELGI_RS04090
uniprot id: F7ZZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

593907:CELGI RS06140
gene id: 593907:CELGI_RS06140
uniprot id: F8A1S1
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS01900
gene id: 593907:CELGI_RS01900
uniprot id: F8A4T0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS04370
gene id: 593907:CELGI_RS04370
uniprot id: F7ZZV8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

593907:CELGI RS06335
gene id: 593907:CELGI_RS06335
uniprot id: F8A2B0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS10545
gene id: 593907:CELGI_RS10545
uniprot id: F7ZZU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS16160
gene id: 593907:CELGI_RS16160
uniprot id: F7ZZF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

593907:CELGI RS10675
gene id: 593907:CELGI_RS10675
uniprot id: F8A053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS02040
gene id: 593907:CELGI_RS02040
uniprot id: F8A5A8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS12050
gene id: 593907:CELGI_RS12050
uniprot id: F8A1K5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

593907:CELGI RS11270
gene id: 593907:CELGI_RS11270
uniprot id: F8A0P5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

593907:CELGI RS13705
gene id: 593907:CELGI_RS13705
uniprot id: F8A4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

593907:CELGI RS15080
gene id: 593907:CELGI_RS15080
uniprot id: F8A6J7
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12130
gene id: 593907:CELGI_RS12130
uniprot id: F8A1W1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

593907:CELGI RS15685
gene id: 593907:CELGI_RS15685
uniprot id: F8A7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

593907:CELGI RS04475
gene id: 593907:CELGI_RS04475
uniprot id: F7ZZX9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

593907:CELGI RS11140
gene id: 593907:CELGI_RS11140
uniprot id: F8A0M3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

593907:CELGI RS08200
gene id: 593907:CELGI_RS08200
uniprot id: F8A533
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

593907:CELGI RS01385
gene id: 593907:CELGI_RS01385
uniprot id: F8A432
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

593907:CELGI RS06135
gene id: 593907:CELGI_RS06135
uniprot id: F8A1S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS15035
gene id: 593907:CELGI_RS15035
uniprot id: F8A6I8
names: Similarity
messages: Belongs to the AHA1 family.

593907:CELGI RS17580
gene id: 593907:CELGI_RS17580
uniprot id: F8A5L4
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

593907:CELGI RS06870
gene id: 593907:CELGI_RS06870
uniprot id: F8A319
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

593907:CELGI RS14355
gene id: 593907:CELGI_RS14355
uniprot id: F8A597
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

593907:CELGI RS03935
gene id: 593907:CELGI_RS03935
uniprot id: F7ZZ24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

593907:CELGI RS09235
gene id: 593907:CELGI_RS09235
uniprot id: F8A6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

593907:CELGI RS16040
gene id: 593907:CELGI_RS16040
uniprot id: F7ZZC7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

593907:CELGI RS11845
gene id: 593907:CELGI_RS11845
uniprot id: F8A1G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

593907:CELGI RS01465
gene id: 593907:CELGI_RS01465
uniprot id: F8A447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

593907:CELGI RS04165
gene id: 593907:CELGI_RS04165
uniprot id: F7ZZJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

593907:CELGI RS11400
gene id: 593907:CELGI_RS11400
uniprot id: F8A0Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

593907:CELGI RS04065
gene id: 593907:CELGI_RS04065
uniprot id: F7ZZH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

593907:CELGI RS04505
gene id: 593907:CELGI_RS04505
uniprot id: F7ZZY5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

593907:CELGI RS00965
gene id: 593907:CELGI_RS00965
uniprot id: F8A3F5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

593907:CELGI RS01460
gene id: 593907:CELGI_RS01460
uniprot id: F8A446
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS01265
gene id: 593907:CELGI_RS01265
uniprot id: F8A411
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

593907:CELGI RS07015
gene id: 593907:CELGI_RS07015
uniprot id: F8A348
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

593907:CELGI RS16055
gene id: 593907:CELGI_RS16055
uniprot id: F7ZZD0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

593907:CELGI RS03665
gene id: 593907:CELGI_RS03665
uniprot id: F7ZYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

593907:CELGI RS00580
gene id: 593907:CELGI_RS00580
uniprot id: F8A2T0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

593907:CELGI RS12500
gene id: 593907:CELGI_RS12500
uniprot id: F8A2I3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS14750
gene id: 593907:CELGI_RS14750
uniprot id: F8A5X9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

593907:CELGI RS03885
gene id: 593907:CELGI_RS03885
uniprot id: F7ZZ17
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

593907:CELGI RS00120
gene id: 593907:CELGI_RS00120
uniprot id: F8A237
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

593907:CELGI RS04375
gene id: 593907:CELGI_RS04375
uniprot id: F7ZZV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

593907:CELGI RS04230
gene id: 593907:CELGI_RS04230
uniprot id: F7ZZK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

593907:CELGI RS15445
gene id: 593907:CELGI_RS15445
uniprot id: F8A771
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

593907:CELGI RS12510
gene id: 593907:CELGI_RS12510
uniprot id: F8A2I5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

593907:CELGI RS11655
gene id: 593907:CELGI_RS11655
uniprot id: F8A151
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

593907:CELGI RS05845
gene id: 593907:CELGI_RS05845
uniprot id: F8A1C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS03735
gene id: 593907:CELGI_RS03735
uniprot id: F7ZYY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

593907:CELGI RS02135
gene id: 593907:CELGI_RS02135
uniprot id: F8A5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

593907:CELGI RS09550
gene id: 593907:CELGI_RS09550
uniprot id: F8A7J6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

593907:CELGI RS10640
gene id: 593907:CELGI_RS10640
uniprot id: F8A046
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

593907:CELGI RS06855
gene id: 593907:CELGI_RS06855
uniprot id: F8A316
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

593907:CELGI RS04195
gene id: 593907:CELGI_RS04195
uniprot id: F7ZZJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

593907:CELGI RS03085
gene id: 593907:CELGI_RS03085
uniprot id: F8A6R8
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS04900
gene id: 593907:CELGI_RS04900
uniprot id: F8A0D9
names: Similarity
messages: Belongs to the peptidase M24B family.

593907:CELGI RS02475
gene id: 593907:CELGI_RS02475
uniprot id: F8A5Z5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

593907:CELGI RS12165
gene id: 593907:CELGI_RS12165
uniprot id: F8A1W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04665
gene id: 593907:CELGI_RS04665
uniprot id: F8A017
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

593907:CELGI RS07990
gene id: 593907:CELGI_RS07990
uniprot id: F8A4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

593907:CELGI RS13165
gene id: 593907:CELGI_RS13165
uniprot id: F8A3B5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS11460
gene id: 593907:CELGI_RS11460
uniprot id: F8A111
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

593907:CELGI RS00020
gene id: 593907:CELGI_RS00020
uniprot id: F8A1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

593907:CELGI RS02010
gene id: 593907:CELGI_RS02010
uniprot id: F8A4V3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

593907:CELGI RS07575
gene id: 593907:CELGI_RS07575
uniprot id: F8A4B1
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

593907:CELGI RS13085
gene id: 593907:CELGI_RS13085
uniprot id: F8A399
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS02310
gene id: 593907:CELGI_RS02310
uniprot id: F8A5G1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

593907:CELGI RS05925
gene id: 593907:CELGI_RS05925
uniprot id: F8A1M8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

593907:CELGI RS02780
gene id: 593907:CELGI_RS02780
uniprot id: F8A654
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

593907:CELGI RS10180
gene id: 593907:CELGI_RS10180
uniprot id: F7ZZA4
names: Similarity
messages: Belongs to the peptidase S9C family.

593907:CELGI RS09345
gene id: 593907:CELGI_RS09345
uniprot id: F8A707
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

593907:CELGI RS15480
gene id: 593907:CELGI_RS15480
uniprot id: F8A778
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

593907:CELGI RS03360
gene id: 593907:CELGI_RS03360
uniprot id: F8A7C3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

593907:CELGI RS10170
gene id: 593907:CELGI_RS10170
uniprot id: F7ZZA2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

593907:CELGI RS00010
gene id: 593907:CELGI_RS00010
uniprot id: F8A1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

593907:CELGI RS08540
gene id: 593907:CELGI_RS08540
uniprot id: F8A5P9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

593907:CELGI RS06935
gene id: 593907:CELGI_RS06935
uniprot id: F8A331
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

593907:CELGI RS09470
gene id: 593907:CELGI_RS09470
uniprot id: F8A7H9
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

593907:CELGI RS13315
gene id: 593907:CELGI_RS13315
uniprot id: F8A3U6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

593907:CELGI RS07555
gene id: 593907:CELGI_RS07555
uniprot id: F8A4A6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

593907:CELGI RS12715
gene id: 593907:CELGI_RS12715
uniprot id: F8A2M5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

593907:CELGI RS06090
gene id: 593907:CELGI_RS06090
uniprot id: F8A1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS03505
gene id: 593907:CELGI_RS03505
uniprot id: F8A7F2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

593907:CELGI RS08180
gene id: 593907:CELGI_RS08180
uniprot id: F8A529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

593907:CELGI RS05285
gene id: 593907:CELGI_RS05285
uniprot id: F8A0T7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

593907:CELGI RS11830
gene id: 593907:CELGI_RS11830
uniprot id: F8A1G1
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS03830
gene id: 593907:CELGI_RS03830
uniprot id: F7ZZ06
names: Similarity
messages: Belongs to the WXG100 family.

593907:CELGI RS07590
gene id: 593907:CELGI_RS07590
uniprot id: F8A4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

593907:CELGI RS04390
gene id: 593907:CELGI_RS04390
uniprot id: F7ZZW2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS04355
gene id: 593907:CELGI_RS04355
uniprot id: F7ZZM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

593907:CELGI RS07020
gene id: 593907:CELGI_RS07020
uniprot id: F8A349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

593907:CELGI RS12745
gene id: 593907:CELGI_RS12745
uniprot id: F8A2N1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

593907:CELGI RS02820
gene id: 593907:CELGI_RS02820
uniprot id: F8A6L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

593907:CELGI RS07490
gene id: 593907:CELGI_RS07490
uniprot id: F8A493
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS14480
gene id: 593907:CELGI_RS14480
uniprot id: F8A5S5
names: Similarity
messages: Belongs to the peptidase S51 family.

593907:CELGI RS02030
gene id: 593907:CELGI_RS02030
uniprot id: F8A5A6
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS09155
gene id: 593907:CELGI_RS09155
uniprot id: F8A6X0
names: Similarity
messages: Belongs to the glutamate synthase family.

593907:CELGI RS07510
gene id: 593907:CELGI_RS07510
uniprot id: F8A497
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

593907:CELGI RS04155
gene id: 593907:CELGI_RS04155
uniprot id: F7ZZI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

593907:CELGI RS04485
gene id: 593907:CELGI_RS04485
uniprot id: F7ZZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

593907:CELGI RS07035
gene id: 593907:CELGI_RS07035
uniprot id: F8A352
names: Similarity
messages: Belongs to the glutamine synthetase family.

593907:CELGI RS16480
gene id: 593907:CELGI_RS16480
uniprot id: F8A660
names: Similarity
messages: Belongs to the UPF0749 family.

593907:CELGI RS07250
gene id: 593907:CELGI_RS07250
uniprot id: F8A3P8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

593907:CELGI RS09885
gene id: 593907:CELGI_RS09885
uniprot id: F7ZZ46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

593907:CELGI RS10450
gene id: 593907:CELGI_RS10450
uniprot id: F7ZZT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

593907:CELGI RS12670
gene id: 593907:CELGI_RS12670
uniprot id: F8A2L6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

593907:CELGI RS11840
gene id: 593907:CELGI_RS11840
uniprot id: F8A1G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

593907:CELGI RS15815
gene id: 593907:CELGI_RS15815
uniprot id: F8A7U8
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

593907:CELGI RS12170
gene id: 593907:CELGI_RS12170
uniprot id: F8A1X0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

593907:CELGI RS03905
gene id: 593907:CELGI_RS03905
uniprot id: F7ZZ21
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

593907:CELGI RS02555
gene id: 593907:CELGI_RS02555
uniprot id: F8A611
names: Similarity
messages: Belongs to the universal stress protein A family.

593907:CELGI RS10850
gene id: 593907:CELGI_RS10850
uniprot id: F8A088
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

593907:CELGI RS07700
gene id: 593907:CELGI_RS07700
uniprot id: F8A4D7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

593907:CELGI RS09360
gene id: 593907:CELGI_RS09360
uniprot id: F8A709
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

593907:CELGI RS10465
gene id: 593907:CELGI_RS10465
uniprot id: F7ZZT3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

593907:CELGI RS09920
gene id: 593907:CELGI_RS09920
uniprot id: F7ZZ52
names: Similarity
messages: Belongs to the Fur family.

593907:CELGI RS13015
gene id: 593907:CELGI_RS13015
uniprot id: F8A387
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS11095
gene id: 593907:CELGI_RS11095
uniprot id: F8A0L4
names: Similarity
messages: Belongs to the UPF0045 family.

593907:CELGI RS09575
gene id: 593907:CELGI_RS09575
uniprot id: F8A7K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

593907:CELGI RS13490
gene id: 593907:CELGI_RS13490
uniprot id: F8A3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

593907:CELGI RS08280
gene id: 593907:CELGI_RS08280
uniprot id: F8A5J7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

593907:CELGI RS04365
gene id: 593907:CELGI_RS04365
uniprot id: F7ZZV7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

593907:CELGI RS15160
gene id: 593907:CELGI_RS15160
uniprot id: F8A6L3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

593907:CELGI RS16630
gene id: 593907:CELGI_RS16630
uniprot id: F8A5W2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS10005
gene id: 593907:CELGI_RS10005
uniprot id: F7ZZ69
names: Subcellular Location Annotation
messages: Cytoplasm

593907:CELGI RS06450
gene id: 593907:CELGI_RS06450
uniprot id: F8A2D3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

593907:CELGI RS02570
gene id: 593907:CELGI_RS02570
uniprot id: F8A614
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS12875
gene id: 593907:CELGI_RS12875
uniprot id: F8A358
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

593907:CELGI RS04135
gene id: 593907:CELGI_RS04135
uniprot id: F7ZZI5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

593907:CELGI RS07355
gene id: 593907:CELGI_RS07355
uniprot id: F8A3R9
names: Similarity
messages: Belongs to the thymidine kinase family.

593907:CELGI RS09305
gene id: 593907:CELGI_RS09305
uniprot id: F8A6Z9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

593907:CELGI RS07860
gene id: 593907:CELGI_RS07860
uniprot id: F8A4W6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS03940
gene id: 593907:CELGI_RS03940
uniprot id: F7ZZ25
names: Similarity
messages: Belongs to the UPF0336 family.

593907:CELGI RS13290
gene id: 593907:CELGI_RS13290
uniprot id: F8A3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

593907:CELGI RS04735
gene id: 593907:CELGI_RS04735
uniprot id: F8A031
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

593907:CELGI RS12260
gene id: 593907:CELGI_RS12260
uniprot id: F8A1Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

593907:CELGI RS09055
gene id: 593907:CELGI_RS09055
uniprot id: F8A6V0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

593907:CELGI RS00365
gene id: 593907:CELGI_RS00365
uniprot id: F8A284
names: Similarity
messages: Belongs to the YciI family.

593907:CELGI RS00075
gene id: 593907:CELGI_RS00075
uniprot id: F8A1M7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

593907:CELGI RS08380
gene id: 593907:CELGI_RS08380
uniprot id: F8A5L7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

593907:CELGI RS04285
gene id: 593907:CELGI_RS04285
uniprot id: F7ZZL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

593907:CELGI RS01805
gene id: 593907:CELGI_RS01805
uniprot id: F8A4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

593907:CELGI RS09020
gene id: 593907:CELGI_RS09020
uniprot id: F8A6U3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

593907:CELGI RS07195
gene id: 593907:CELGI_RS07195
uniprot id: F8A3N7
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS17500
gene id: 593907:CELGI_RS17500
uniprot id: F8A3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

593907:CELGI RS16115
gene id: 593907:CELGI_RS16115
uniprot id: F7ZZE2
names: Similarity
messages: Belongs to the ParB family.

593907:CELGI RS10635
gene id: 593907:CELGI_RS10635
uniprot id: F8A045
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

593907:CELGI RS06435
gene id: 593907:CELGI_RS06435
uniprot id: F8A2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS16015
gene id: 593907:CELGI_RS16015
uniprot id: F7ZZC2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

593907:CELGI RS09995
gene id: 593907:CELGI_RS09995
uniprot id: F7ZZ67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

593907:CELGI RS12690
gene id: 593907:CELGI_RS12690
uniprot id: F8A2M0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

593907:CELGI RS12520
gene id: 593907:CELGI_RS12520
uniprot id: F8A2I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

593907:CELGI RS08040
gene id: 593907:CELGI_RS08040
uniprot id: F8A501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

593907:CELGI RS09875
gene id: 593907:CELGI_RS09875
uniprot id: F7ZZ44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

593907:CELGI RS00160
gene id: 593907:CELGI_RS00160
uniprot id: F8A245
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS04825
gene id: 593907:CELGI_RS04825
uniprot id: F8A0C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS04085
gene id: 593907:CELGI_RS04085
uniprot id: F7ZZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

593907:CELGI RS00375
gene id: 593907:CELGI_RS00375
uniprot id: F8A286
names: Subcellular Location Annotation
messages: Cytoplasm

593907:CELGI RS14625
gene id: 593907:CELGI_RS14625
uniprot id: F8A5V4
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS05325
gene id: 593907:CELGI_RS05325
uniprot id: F8A0U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS11065
gene id: 593907:CELGI_RS11065
uniprot id: F8A0K8
names: Similarity
messages: Belongs to the peptidase M13 family.

593907:CELGI RS13925
gene id: 593907:CELGI_RS13925
uniprot id: F8A4K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

593907:CELGI RS09275
gene id: 593907:CELGI_RS09275
uniprot id: F8A6Z3
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

593907:CELGI RS08310
gene id: 593907:CELGI_RS08310
uniprot id: F8A5K3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

593907:CELGI RS13280
gene id: 593907:CELGI_RS13280
uniprot id: F8A3T9
names: Similarity
messages: Belongs to the malic enzymes family.

593907:CELGI RS08925
gene id: 593907:CELGI_RS08925
uniprot id: F8A6C2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

593907:CELGI RS01970
gene id: 593907:CELGI_RS01970
uniprot id: F8A4U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

593907:CELGI RS05065
gene id: 593907:CELGI_RS05065
uniprot id: F8A0H2
names: Similarity
messages: Belongs to the alkaline phosphatase family.

593907:CELGI RS15180
gene id: 593907:CELGI_RS15180
uniprot id: F8A718
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

593907:CELGI RS08985
gene id: 593907:CELGI_RS08985
uniprot id: F8A6D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

593907:CELGI RS11350
gene id: 593907:CELGI_RS11350
uniprot id: F8A0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

593907:CELGI RS00480
gene id: 593907:CELGI_RS00480
uniprot id: F8A2R0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

593907:CELGI RS07650
gene id: 593907:CELGI_RS07650
uniprot id: F8A4C7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

593907:CELGI RS12825
gene id: 593907:CELGI_RS12825
uniprot id: F8A2P8
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS00770
gene id: 593907:CELGI_RS00770
uniprot id: F8A2W3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

593907:CELGI RS10610
gene id: 593907:CELGI_RS10610
uniprot id: F8A040
names: Similarity
messages: Belongs to the UPF0102 family.

593907:CELGI RS10535
gene id: 593907:CELGI_RS10535
uniprot id: F7ZZU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

593907:CELGI RS09965
gene id: 593907:CELGI_RS09965
uniprot id: F7ZZ61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

593907:CELGI RS01205
gene id: 593907:CELGI_RS01205
uniprot id: F8A3J8
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS00390
gene id: 593907:CELGI_RS00390
uniprot id: F8A289
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS10905
gene id: 593907:CELGI_RS10905
uniprot id: F8A0A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

593907:CELGI RS08330
gene id: 593907:CELGI_RS08330
uniprot id: F8A5K7
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

593907:CELGI RS06000
gene id: 593907:CELGI_RS06000
uniprot id: F8A1P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

593907:CELGI RS01875
gene id: 593907:CELGI_RS01875
uniprot id: F8A4S5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

593907:CELGI RS05040
gene id: 593907:CELGI_RS05040
uniprot id: F8A0G8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

593907:CELGI RS10390
gene id: 593907:CELGI_RS10390
uniprot id: F7ZZR8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

593907:CELGI RS09960
gene id: 593907:CELGI_RS09960
uniprot id: F7ZZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

593907:CELGI RS11245
gene id: 593907:CELGI_RS11245
uniprot id: F8A0P0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12420
gene id: 593907:CELGI_RS12420
uniprot id: F8A216
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

593907:CELGI RS09910
gene id: 593907:CELGI_RS09910
uniprot id: F7ZZ51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

593907:CELGI RS11035
gene id: 593907:CELGI_RS11035
uniprot id: F8A0K2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

593907:CELGI RS12145
gene id: 593907:CELGI_RS12145
uniprot id: F8A1W4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

593907:CELGI RS10650
gene id: 593907:CELGI_RS10650
uniprot id: F8A048
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

593907:CELGI RS01815
gene id: 593907:CELGI_RS01815
uniprot id: F8A4R2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

593907:CELGI RS13735
gene id: 593907:CELGI_RS13735
uniprot id: F8A4H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

593907:CELGI RS13580
gene id: 593907:CELGI_RS13580
uniprot id: F8A401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS09480
gene id: 593907:CELGI_RS09480
uniprot id: F8A7I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

593907:CELGI RS10510
gene id: 593907:CELGI_RS10510
uniprot id: F7ZZU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS05600
gene id: 593907:CELGI_RS05600
uniprot id: F8A175
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

593907:CELGI RS05910
gene id: 593907:CELGI_RS05910
uniprot id: F8A1D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

593907:CELGI RS04585
gene id: 593907:CELGI_RS04585
uniprot id: F8A001
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

593907:CELGI RS01925
gene id: 593907:CELGI_RS01925
uniprot id: F8A4T5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

593907:CELGI RS16035
gene id: 593907:CELGI_RS16035
uniprot id: F7ZZC6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS11205
gene id: 593907:CELGI_RS11205
uniprot id: F8A0N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

593907:CELGI RS15320
gene id: 593907:CELGI_RS15320
uniprot id: F8A746
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

593907:CELGI RS10690
gene id: 593907:CELGI_RS10690
uniprot id: F8A056
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

593907:CELGI RS10010
gene id: 593907:CELGI_RS10010
uniprot id: F7ZZ70
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

593907:CELGI RS07180
gene id: 593907:CELGI_RS07180
uniprot id: F8A3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

593907:CELGI RS05990
gene id: 593907:CELGI_RS05990
uniprot id: F8A1P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS03610
gene id: 593907:CELGI_RS03610
uniprot id: F7ZYW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS04290
gene id: 593907:CELGI_RS04290
uniprot id: F7ZZL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

593907:CELGI RS07825
gene id: 593907:CELGI_RS07825
uniprot id: F8A4V8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

593907:CELGI RS10445
gene id: 593907:CELGI_RS10445
uniprot id: F7ZZS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

593907:CELGI RS12975
gene id: 593907:CELGI_RS12975
uniprot id: F8A379
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS08290
gene id: 593907:CELGI_RS08290
uniprot id: F8A5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

593907:CELGI RS09725
gene id: 593907:CELGI_RS09725
uniprot id: F8A7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS12980
gene id: 593907:CELGI_RS12980
uniprot id: F8A380
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS02790
gene id: 593907:CELGI_RS02790
uniprot id: F8A656
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

593907:CELGI RS12375
gene id: 593907:CELGI_RS12375
uniprot id: F8A207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS09260
gene id: 593907:CELGI_RS09260
uniprot id: F8A6Z0
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

593907:CELGI RS08950
gene id: 593907:CELGI_RS08950
uniprot id: F8A6C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

593907:CELGI RS05995
gene id: 593907:CELGI_RS05995
uniprot id: F8A1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

593907:CELGI RS10405
gene id: 593907:CELGI_RS10405
uniprot id: F7ZZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

593907:CELGI RS14525
gene id: 593907:CELGI_RS14525
uniprot id: F8A5T4
names: Similarity
messages: Belongs to the FPG family.

593907:CELGI RS05860
gene id: 593907:CELGI_RS05860
uniprot id: F8A1C5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

593907:CELGI RS13770
gene id: 593907:CELGI_RS13770
uniprot id: F8A4I0
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

593907:CELGI RS07210
gene id: 593907:CELGI_RS07210
uniprot id: F8A3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS14135
gene id: 593907:CELGI_RS14135
uniprot id: F8A553
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

593907:CELGI RS05350
gene id: 593907:CELGI_RS05350
uniprot id: F8A0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS07085
gene id: 593907:CELGI_RS07085
uniprot id: F8A3L4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

593907:CELGI RS04140
gene id: 593907:CELGI_RS04140
uniprot id: F7ZZI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

593907:CELGI RS12355
gene id: 593907:CELGI_RS12355
uniprot id: F8A203
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

593907:CELGI RS01955
gene id: 593907:CELGI_RS01955
uniprot id: F8A4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

593907:CELGI RS12695
gene id: 593907:CELGI_RS12695
uniprot id: F8A2M1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

593907:CELGI RS16295
gene id: 593907:CELGI_RS16295
uniprot id: F7ZZG4
names: Similarity
messages: Belongs to the peptidase S1 family.

593907:CELGI RS12675
gene id: 593907:CELGI_RS12675
uniprot id: F8A2L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

593907:CELGI RS14350
gene id: 593907:CELGI_RS14350
uniprot id: F8A596
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS12400
gene id: 593907:CELGI_RS12400
uniprot id: F8A212
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

593907:CELGI RS01470
gene id: 593907:CELGI_RS01470
uniprot id: F8A448
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

593907:CELGI RS11960
gene id: 593907:CELGI_RS11960
uniprot id: F8A1I6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

593907:CELGI RS02785
gene id: 593907:CELGI_RS02785
uniprot id: F8A655
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

593907:CELGI RS09710
gene id: 593907:CELGI_RS09710
uniprot id: F8A7M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS00665
gene id: 593907:CELGI_RS00665
uniprot id: F8A2U6
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS10645
gene id: 593907:CELGI_RS10645
uniprot id: F8A047
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

593907:CELGI RS16290
gene id: 593907:CELGI_RS16290
uniprot id: F7ZZ05
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS10525
gene id: 593907:CELGI_RS10525
uniprot id: F7ZZU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

593907:CELGI RS09675
gene id: 593907:CELGI_RS09675
uniprot id: F8A7M0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

593907:CELGI RS16125
gene id: 593907:CELGI_RS16125
uniprot id: F7ZZE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

593907:CELGI RS14920
gene id: 593907:CELGI_RS14920
uniprot id: F8A6G5
names: Similarity
messages: Belongs to the YciI family.

593907:CELGI RS12430
gene id: 593907:CELGI_RS12430
uniprot id: F8A218
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

593907:CELGI RS03695
gene id: 593907:CELGI_RS03695
uniprot id: F7ZYY0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS08440
gene id: 593907:CELGI_RS08440
uniprot id: F8A5M9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

593907:CELGI RS00535
gene id: 593907:CELGI_RS00535
uniprot id: F8A2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

593907:CELGI RS02430
gene id: 593907:CELGI_RS02430
uniprot id: F8A5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

593907:CELGI RS16065
gene id: 593907:CELGI_RS16065
uniprot id: F7ZZD2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12740
gene id: 593907:CELGI_RS12740
uniprot id: F8A2N0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

593907:CELGI RS01010
gene id: 593907:CELGI_RS01010
uniprot id: F8A3G2
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS05765
gene id: 593907:CELGI_RS05765
uniprot id: F8A1A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

593907:CELGI RS10070
gene id: 593907:CELGI_RS10070
uniprot id: F7ZZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

593907:CELGI RS04560
gene id: 593907:CELGI_RS04560
uniprot id: F7ZZZ6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

593907:CELGI RS07845
gene id: 593907:CELGI_RS07845
uniprot id: F8A4W3
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12485
gene id: 593907:CELGI_RS12485
uniprot id: F8A2I0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

593907:CELGI RS11440
gene id: 593907:CELGI_RS11440
uniprot id: F8A107
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

593907:CELGI RS12015
gene id: 593907:CELGI_RS12015
uniprot id: F8A1J8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

593907:CELGI RS00475
gene id: 593907:CELGI_RS00475
uniprot id: F8A2Q9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

593907:CELGI RS01475
gene id: 593907:CELGI_RS01475
uniprot id: F8A449
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

593907:CELGI RS11995
gene id: 593907:CELGI_RS11995
uniprot id: F8A1J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS02870
gene id: 593907:CELGI_RS02870
uniprot id: F8A6M7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

593907:CELGI RS02470
gene id: 593907:CELGI_RS02470
uniprot id: F8A5Z4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

593907:CELGI RS07205
gene id: 593907:CELGI_RS07205
uniprot id: F8A3N9
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

593907:CELGI RS13020
gene id: 593907:CELGI_RS13020
uniprot id: F8A388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS11105
gene id: 593907:CELGI_RS11105
uniprot id: F8A0L6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

593907:CELGI RS02280
gene id: 593907:CELGI_RS02280
uniprot id: F8A5F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

593907:CELGI RS15780
gene id: 593907:CELGI_RS15780
uniprot id: F8A7U1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

593907:CELGI RS06290
gene id: 593907:CELGI_RS06290
uniprot id: F8A1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS17480
gene id: 593907:CELGI_RS17480
uniprot id: F8A391
names: Similarity
messages: Belongs to the UPF0145 family.

593907:CELGI RS03130
gene id: 593907:CELGI_RS03130
uniprot id: F8A6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

593907:CELGI RS15045
gene id: 593907:CELGI_RS15045
uniprot id: F8A6J0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

593907:CELGI RS04200
gene id: 593907:CELGI_RS04200
uniprot id: F7ZZJ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

593907:CELGI RS11115
gene id: 593907:CELGI_RS11115
uniprot id: F8A0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

593907:CELGI RS15220
gene id: 593907:CELGI_RS15220
uniprot id: F8A726
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS12620
gene id: 593907:CELGI_RS12620
uniprot id: F8A2K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

593907:CELGI RS12425
gene id: 593907:CELGI_RS12425
uniprot id: F8A217
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

593907:CELGI RS13170
gene id: 593907:CELGI_RS13170
uniprot id: F8A3B6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS03430
gene id: 593907:CELGI_RS03430
uniprot id: F8A7D7
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS04205
gene id: 593907:CELGI_RS04205
uniprot id: F7ZZJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

593907:CELGI RS06395
gene id: 593907:CELGI_RS06395
uniprot id: F8A2C2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS01560
gene id: 593907:CELGI_RS01560
uniprot id: F8A466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS02415
gene id: 593907:CELGI_RS02415
uniprot id: F8A5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

593907:CELGI RS15650
gene id: 593907:CELGI_RS15650
uniprot id: F8A7R5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS10300
gene id: 593907:CELGI_RS10300
uniprot id: F7ZZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS11935
gene id: 593907:CELGI_RS11935
uniprot id: F8A1I1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

593907:CELGI RS06235
gene id: 593907:CELGI_RS06235
uniprot id: F8A1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

593907:CELGI RS08555
gene id: 593907:CELGI_RS08555
uniprot id: F8A5Q2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

593907:CELGI RS07305
gene id: 593907:CELGI_RS07305
uniprot id: F8A3Q9
names: Similarity
messages: Belongs to the universal stress protein A family.

593907:CELGI RS08285
gene id: 593907:CELGI_RS08285
uniprot id: F8A5J8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS05840
gene id: 593907:CELGI_RS05840
uniprot id: F8A1C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

593907:CELGI RS11305
gene id: 593907:CELGI_RS11305
uniprot id: F8A0Q2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

593907:CELGI RS04160
gene id: 593907:CELGI_RS04160
uniprot id: F7ZZI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

593907:CELGI RS03670
gene id: 593907:CELGI_RS03670
uniprot id: F7ZYX4
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS14240
gene id: 593907:CELGI_RS14240
uniprot id: F8A574
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS04050
gene id: 593907:CELGI_RS04050
uniprot id: F7ZZG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

593907:CELGI RS01485
gene id: 593907:CELGI_RS01485
uniprot id: F8A451
names: Similarity
messages: Belongs to the Nth/MutY family.

593907:CELGI RS03990
gene id: 593907:CELGI_RS03990
uniprot id: F7ZZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS04295
gene id: 593907:CELGI_RS04295
uniprot id: F7ZZL6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

593907:CELGI RS07485
gene id: 593907:CELGI_RS07485
uniprot id: F8A492
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

593907:CELGI RS04715
gene id: 593907:CELGI_RS04715
uniprot id: F8A027
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

593907:CELGI RS11930
gene id: 593907:CELGI_RS11930
uniprot id: F8A1I0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

593907:CELGI RS02155
gene id: 593907:CELGI_RS02155
uniprot id: F8A5D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

593907:CELGI RS01915
gene id: 593907:CELGI_RS01915
uniprot id: F8A4T3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

593907:CELGI RS06485
gene id: 593907:CELGI_RS06485
uniprot id: F8A2E0
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS11650
gene id: 593907:CELGI_RS11650
uniprot id: F8A150
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

593907:CELGI RS07185
gene id: 593907:CELGI_RS07185
uniprot id: F8A3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

593907:CELGI RS00125
gene id: 593907:CELGI_RS00125
uniprot id: F8A238
names: Similarity
messages: Belongs to the UPF0749 family.

593907:CELGI RS15120
gene id: 593907:CELGI_RS15120
uniprot id: F8A6K5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

593907:CELGI RS09760
gene id: 593907:CELGI_RS09760
uniprot id: F8A7N7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

593907:CELGI RS05985
gene id: 593907:CELGI_RS05985
uniprot id: F8A1P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

593907:CELGI RS03365
gene id: 593907:CELGI_RS03365
uniprot id: F8A7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

593907:CELGI RS09895
gene id: 593907:CELGI_RS09895
uniprot id: F7ZZ48
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

593907:CELGI RS06385
gene id: 593907:CELGI_RS06385
uniprot id: F8A2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS03160
gene id: 593907:CELGI_RS03160
uniprot id: F8A6T3
names: Similarity
messages: Belongs to the malate synthase family.

593907:CELGI RS08340
gene id: 593907:CELGI_RS08340
uniprot id: F8A5K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

593907:CELGI RS10795
gene id: 593907:CELGI_RS10795
uniprot id: F8A077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS15175
gene id: 593907:CELGI_RS15175
uniprot id: F8A717
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

593907:CELGI RS14815
gene id: 593907:CELGI_RS14815
uniprot id: F8A6E4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

593907:CELGI RS07970
gene id: 593907:CELGI_RS07970
uniprot id: F8A4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

593907:CELGI RS03640
gene id: 593907:CELGI_RS03640
uniprot id: F7ZYW8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

593907:CELGI RS04865
gene id: 593907:CELGI_RS04865
uniprot id: F8A0D2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

593907:CELGI RS10815
gene id: 593907:CELGI_RS10815
uniprot id: F8A081
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

593907:CELGI RS13345
gene id: 593907:CELGI_RS13345
uniprot id: F8A3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

593907:CELGI RS10730
gene id: 593907:CELGI_RS10730
uniprot id: F8A064
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

593907:CELGI RS12660
gene id: 593907:CELGI_RS12660
uniprot id: F8A2L4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

593907:CELGI RS14505
gene id: 593907:CELGI_RS14505
uniprot id: F8A5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

593907:CELGI RS13755
gene id: 593907:CELGI_RS13755
uniprot id: F8A4H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

593907:CELGI RS05110
gene id: 593907:CELGI_RS05110
uniprot id: F8A0I1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

593907:CELGI RS08885
gene id: 593907:CELGI_RS08885
uniprot id: F8A6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

593907:CELGI RS04620
gene id: 593907:CELGI_RS04620
uniprot id: F8A008
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

593907:CELGI RS11320
gene id: 593907:CELGI_RS11320
uniprot id: F8A0Q6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS10365
gene id: 593907:CELGI_RS10365
uniprot id: F7ZZR3
names: Similarity
messages: Belongs to the CapA family.

593907:CELGI RS04255
gene id: 593907:CELGI_RS04255
uniprot id: F7ZZK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

593907:CELGI RS12815
gene id: 593907:CELGI_RS12815
uniprot id: F8A2P6
names: Similarity
messages: Belongs to the LOG family.

593907:CELGI RS03700
gene id: 593907:CELGI_RS03700
uniprot id: F7ZYY1
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

593907:CELGI RS02860
gene id: 593907:CELGI_RS02860
uniprot id: F8A6M5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

593907:CELGI RS09525
gene id: 593907:CELGI_RS09525
uniprot id: F8A7J1
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS04615
gene id: 593907:CELGI_RS04615
uniprot id: F8A007
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

593907:CELGI RS12075
gene id: 593907:CELGI_RS12075
uniprot id: F8A1L0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS10785
gene id: 593907:CELGI_RS10785
uniprot id: F8A075
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS04760
gene id: 593907:CELGI_RS04760
uniprot id: F8A0B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

593907:CELGI RS07690
gene id: 593907:CELGI_RS07690
uniprot id: F8A4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

593907:CELGI RS12005
gene id: 593907:CELGI_RS12005
uniprot id: F8A1J6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS08190
gene id: 593907:CELGI_RS08190
uniprot id: F8A531
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS08050
gene id: 593907:CELGI_RS08050
uniprot id: F8A503
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS04280
gene id: 593907:CELGI_RS04280
uniprot id: F7ZZL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

593907:CELGI RS12880
gene id: 593907:CELGI_RS12880
uniprot id: F8A359
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

593907:CELGI RS15540
gene id: 593907:CELGI_RS15540
uniprot id: F8A789
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS05030
gene id: 593907:CELGI_RS05030
uniprot id: F8A0G6
names: Similarity
messages: Belongs to the Fur family.

593907:CELGI RS08300
gene id: 593907:CELGI_RS08300
uniprot id: F8A5K1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

593907:CELGI RS05385
gene id: 593907:CELGI_RS05385
uniprot id: F8A0V7
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS11300
gene id: 593907:CELGI_RS11300
uniprot id: F8A0Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

593907:CELGI RS10670
gene id: 593907:CELGI_RS10670
uniprot id: F8A052
names: Similarity
messages: Belongs to the P(II) protein family.

593907:CELGI RS04020
gene id: 593907:CELGI_RS04020
uniprot id: F7ZZG2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

593907:CELGI RS04265
gene id: 593907:CELGI_RS04265
uniprot id: F7ZZL0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

593907:CELGI RS10515
gene id: 593907:CELGI_RS10515
uniprot id: F7ZZU2
names: Similarity
messages: Belongs to the FPG family.

593907:CELGI RS02900
gene id: 593907:CELGI_RS02900
uniprot id: F8A6N2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

593907:CELGI RS11330
gene id: 593907:CELGI_RS11330
uniprot id: F8A0Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS08260
gene id: 593907:CELGI_RS08260
uniprot id: F8A5J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

593907:CELGI RS15535
gene id: 593907:CELGI_RS15535
uniprot id: F8A788
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

593907:CELGI RS03500
gene id: 593907:CELGI_RS03500
uniprot id: F8A7F1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

593907:CELGI RS03955
gene id: 593907:CELGI_RS03955
uniprot id: F7ZZ28
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS09125
gene id: 593907:CELGI_RS09125
uniprot id: F8A6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS10805
gene id: 593907:CELGI_RS10805
uniprot id: F8A079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

593907:CELGI RS15360
gene id: 593907:CELGI_RS15360
uniprot id: F8A754
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS13715
gene id: 593907:CELGI_RS13715
uniprot id: F8A4G9
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

593907:CELGI RS04640
gene id: 593907:CELGI_RS04640
uniprot id: F8A012
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS03750
gene id: 593907:CELGI_RS03750
uniprot id: F7ZYZ1
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

593907:CELGI RS08965
gene id: 593907:CELGI_RS08965
uniprot id: F8A6D0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

593907:CELGI RS10240
gene id: 593907:CELGI_RS10240
uniprot id: F7ZZN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

593907:CELGI RS06350
gene id: 593907:CELGI_RS06350
uniprot id: F8A2B3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

593907:CELGI RS13300
gene id: 593907:CELGI_RS13300
uniprot id: F8A3U3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS13600
gene id: 593907:CELGI_RS13600
uniprot id: F8A405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS09065
gene id: 593907:CELGI_RS09065
uniprot id: F8A6V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

593907:CELGI RS11355
gene id: 593907:CELGI_RS11355
uniprot id: F8A0Z0
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

593907:CELGI RS04870
gene id: 593907:CELGI_RS04870
uniprot id: F8A0D3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

593907:CELGI RS02315
gene id: 593907:CELGI_RS02315
uniprot id: F8A5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

593907:CELGI RS06260
gene id: 593907:CELGI_RS06260
uniprot id: F8A1U5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

593907:CELGI RS01895
gene id: 593907:CELGI_RS01895
uniprot id: F8A4S9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS02065
gene id: 593907:CELGI_RS02065
uniprot id: F8A5B3
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

593907:CELGI RS15655
gene id: 593907:CELGI_RS15655
uniprot id: F8A7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS14780
gene id: 593907:CELGI_RS14780
uniprot id: F8A6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS07415
gene id: 593907:CELGI_RS07415
uniprot id: F8A3T1
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS09825
gene id: 593907:CELGI_RS09825
uniprot id: F7ZZ34
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS16415
gene id: 593907:CELGI_RS16415
uniprot id: F8A2Z1
names: Similarity
messages: Belongs to the ParB family.

593907:CELGI RS11285
gene id: 593907:CELGI_RS11285
uniprot id: F8A0P8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

593907:CELGI RS11570
gene id: 593907:CELGI_RS11570
uniprot id: F8A133
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

593907:CELGI RS01950
gene id: 593907:CELGI_RS01950
uniprot id: F8A4U0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

593907:CELGI RS01695
gene id: 593907:CELGI_RS01695
uniprot id: F8A4N9
names: Similarity
messages: Belongs to the peptidase S8 family.

593907:CELGI RS04000
gene id: 593907:CELGI_RS04000
uniprot id: F7ZZF9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS08270
gene id: 593907:CELGI_RS08270
uniprot id: F8A5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

593907:CELGI RS04235
gene id: 593907:CELGI_RS04235
uniprot id: F7ZZK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

593907:CELGI RS05085
gene id: 593907:CELGI_RS05085
uniprot id: F8A0H6
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS15270
gene id: 593907:CELGI_RS15270
uniprot id: F8A736
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS17690
gene id: 593907:CELGI_RS17690
uniprot id: F8A5Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

593907:CELGI RS04945
gene id: 593907:CELGI_RS04945
uniprot id: F8A0E8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

593907:CELGI RS16085
gene id: 593907:CELGI_RS16085
uniprot id: F7ZZD6
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS03900
gene id: 593907:CELGI_RS03900
uniprot id: F7ZZ20
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

593907:CELGI RS10040
gene id: 593907:CELGI_RS10040
uniprot id: F7ZZ76
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

593907:CELGI RS01540
gene id: 593907:CELGI_RS01540
uniprot id: F8A462
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

593907:CELGI RS13750
gene id: 593907:CELGI_RS13750
uniprot id: F8A4H6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

593907:CELGI RS05185
gene id: 593907:CELGI_RS05185
uniprot id: F8A0R7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

593907:CELGI RS14390
gene id: 593907:CELGI_RS14390
uniprot id: F8A5A4
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS02540
gene id: 593907:CELGI_RS02540
uniprot id: F8A608
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

593907:CELGI RS08590
gene id: 593907:CELGI_RS08590
uniprot id: F8A5Q9
names: Similarity
messages: Belongs to the UPF0749 family.

593907:CELGI RS03035
gene id: 593907:CELGI_RS03035
uniprot id: F8A6Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

593907:CELGI RS07270
gene id: 593907:CELGI_RS07270
uniprot id: F8A3Q2
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

593907:CELGI RS13830
gene id: 593907:CELGI_RS13830
uniprot id: F8A4J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

593907:CELGI RS11990
gene id: 593907:CELGI_RS11990
uniprot id: F8A1J3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

593907:CELGI RS11250
gene id: 593907:CELGI_RS11250
uniprot id: F8A0P1
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS15525
gene id: 593907:CELGI_RS15525
uniprot id: F8A787
names: Similarity
messages: Belongs to the peptidase S9C family.

593907:CELGI RS07570
gene id: 593907:CELGI_RS07570
uniprot id: F8A4A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

593907:CELGI RS08320
gene id: 593907:CELGI_RS08320
uniprot id: F8A5K5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

593907:CELGI RS05710
gene id: 593907:CELGI_RS05710
uniprot id: F8A197
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS00860
gene id: 593907:CELGI_RS00860
uniprot id: F8A2Y1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

593907:CELGI RS04785
gene id: 593907:CELGI_RS04785
uniprot id: F8A0B6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

593907:CELGI RS10565
gene id: 593907:CELGI_RS10565
uniprot id: F7ZZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

593907:CELGI RS09375
gene id: 593907:CELGI_RS09375
uniprot id: F8A712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

593907:CELGI RS02855
gene id: 593907:CELGI_RS02855
uniprot id: F8A6M4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

593907:CELGI RS04245
gene id: 593907:CELGI_RS04245
uniprot id: F7ZZK6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

593907:CELGI RS10095
gene id: 593907:CELGI_RS10095
uniprot id: F7ZZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

593907:CELGI RS11725
gene id: 593907:CELGI_RS11725
uniprot id: F8A1D9
names: Similarity
messages: Belongs to the GSP E family.

593907:CELGI RS02300
gene id: 593907:CELGI_RS02300
uniprot id: F8A5F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

593907:CELGI RS08755
gene id: 593907:CELGI_RS08755
uniprot id: F8A688
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

593907:CELGI RS09640
gene id: 593907:CELGI_RS09640
uniprot id: F8A7L3
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS00640
gene id: 593907:CELGI_RS00640
uniprot id: F8A2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

593907:CELGI RS02510
gene id: 593907:CELGI_RS02510
uniprot id: F8A602
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

593907:CELGI RS03755
gene id: 593907:CELGI_RS03755
uniprot id: F7ZYZ2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

593907:CELGI RS10315
gene id: 593907:CELGI_RS10315
uniprot id: F7ZZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

593907:CELGI RS02360
gene id: 593907:CELGI_RS02360
uniprot id: F8A5H0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

593907:CELGI RS13330
gene id: 593907:CELGI_RS13330
uniprot id: F8A3U9
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

593907:CELGI RS10305
gene id: 593907:CELGI_RS10305
uniprot id: F7ZZQ1
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

593907:CELGI RS04575
gene id: 593907:CELGI_RS04575
uniprot id: F7ZZZ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

593907:CELGI RS02795
gene id: 593907:CELGI_RS02795
uniprot id: F8A657
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

593907:CELGI RS03855
gene id: 593907:CELGI_RS03855
uniprot id: F7ZZ11
names: Similarity
messages: Belongs to the WXG100 family.

593907:CELGI RS02285
gene id: 593907:CELGI_RS02285
uniprot id: F8A5F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

593907:CELGI RS12190
gene id: 593907:CELGI_RS12190
uniprot id: F8A1X4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

593907:CELGI RS11530
gene id: 593907:CELGI_RS11530
uniprot id: F8A125
names: Subcellular Location Annotation
messages: Membrane

593907:CELGI RS03740
gene id: 593907:CELGI_RS03740
uniprot id: F7ZYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

593907:CELGI RS14740
gene id: 593907:CELGI_RS14740
uniprot id: F8A5X7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

593907:CELGI RS01185
gene id: 593907:CELGI_RS01185
uniprot id: F8A3J3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

593907:CELGI RS08325
gene id: 593907:CELGI_RS08325
uniprot id: F8A5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

593907:CELGI RS05605
gene id: 593907:CELGI_RS05605
uniprot id: F8A176
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

593907:CELGI RS04360
gene id: 593907:CELGI_RS04360
uniprot id: F7ZZM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

593907:CELGI RS15215
gene id: 593907:CELGI_RS15215
uniprot id: F8A725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

593907:CELGI RS07130
gene id: 593907:CELGI_RS07130
uniprot id: F8A3M4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

593907:CELGI RS05615
gene id: 593907:CELGI_RS05615
uniprot id: F8A178
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

593907:CELGI RS02340
gene id: 593907:CELGI_RS02340
uniprot id: F8A5G7
names: Similarity
messages: Belongs to the peptidase C40 family.

593907:CELGI RS04075
gene id: 593907:CELGI_RS04075
uniprot id: F7ZZH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

593907:CELGI RS12435
gene id: 593907:CELGI_RS12435
uniprot id: F8A219
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

593907:CELGI RS02385
gene id: 593907:CELGI_RS02385
uniprot id: F8A5H5
names: Similarity
messages: Belongs to the MotB family.

593907:CELGI RS07330
gene id: 593907:CELGI_RS07330
uniprot id: F8A3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

593907:CELGI RS08900
gene id: 593907:CELGI_RS08900
uniprot id: F8A6B7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

593907:CELGI RS13955
gene id: 593907:CELGI_RS13955
uniprot id: F8A4L5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

593907:CELGI RS04740
gene id: 593907:CELGI_RS04740
uniprot id: F8A032
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

593907:CELGI RS05895
gene id: 593907:CELGI_RS05895
uniprot id: F8A1D2
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

593907:CELGI RS00700
gene id: 593907:CELGI_RS00700
uniprot id: F8A2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

593907:CELGI RS01125
gene id: 593907:CELGI_RS01125
uniprot id: F8A3I1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

593907:CELGI RS09485
gene id: 593907:CELGI_RS09485
uniprot id: F8A7I2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

593907:CELGI RS06410
gene id: 593907:CELGI_RS06410
uniprot id: F8A2C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

593907:CELGI RS12475
gene id: 593907:CELGI_RS12475
uniprot id: F8A227
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

593907:CELGI RS03175
gene id: 593907:CELGI_RS03175
uniprot id: F8A6T6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

593907:CELGI RS12575
gene id: 593907:CELGI_RS12575
uniprot id: F8A2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

593907:CELGI RS02320
gene id: 593907:CELGI_RS02320
uniprot id: F8A5G3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

593907:CELGI RS12285
gene id: 593907:CELGI_RS12285
uniprot id: F8A1Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

593907:CELGI RS04590
gene id: 593907:CELGI_RS04590
uniprot id: F8A002
names: Similarity
messages: Belongs to the XFP family.

593907:CELGI RS05780
gene id: 593907:CELGI_RS05780
uniprot id: F8A1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

593907:CELGI RS04170
gene id: 593907:CELGI_RS04170
uniprot id: F7ZZJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

593907:CELGI RS03395
gene id: 593907:CELGI_RS03395
uniprot id: F8A7D0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

593907:CELGI RS02545
gene id: 593907:CELGI_RS02545
uniprot id: F8A609
names: Similarity
messages: Belongs to the peptidase C40 family.