590998:CELF RS10620
gene id: 590998:CELF_RS10620
uniprot id: F4H0Y2
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS04815
gene id: 590998:CELF_RS04815
uniprot id: F4H1C5
names: Similarity
messages: Belongs to the EccD/Snm4 family.

590998:CELF RS01375
gene id: 590998:CELF_RS01375
uniprot id: F4H6B1
names: Similarity
messages: Belongs to the RutC family.

590998:CELF RS13465
gene id: 590998:CELF_RS13465
uniprot id: F4H6N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

590998:CELF RS18180
gene id: 590998:CELF_RS18180
uniprot id: F4H3N9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

590998:CELF RS04555
gene id: 590998:CELF_RS04555
uniprot id: F4H0R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

590998:CELF RS12125
gene id: 590998:CELF_RS12125
uniprot id: F4H3I4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

590998:CELF RS19540
gene id: 590998:CELF_RS19540
uniprot id: F4H2W3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07200
gene id: 590998:CELF_RS07200
uniprot id: F4H5W4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

590998:CELF RS04620
gene id: 590998:CELF_RS04620
uniprot id: F4H0T1
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS08125
gene id: 590998:CELF_RS08125
uniprot id: F4H7R3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05465
gene id: 590998:CELF_RS05465
uniprot id: F4H2J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

590998:CELF RS04025
gene id: 590998:CELF_RS04025
uniprot id: F4H023
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS10060
gene id: 590998:CELF_RS10060
uniprot id: F4H074
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS02720
gene id: 590998:CELF_RS02720
uniprot id: F4GY18
names: Similarity
messages: Belongs to the UPF0045 family.

590998:CELF RS14715
gene id: 590998:CELF_RS14715
uniprot id: F4H8N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

590998:CELF RS12130
gene id: 590998:CELF_RS12130
uniprot id: F4H3I5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

590998:CELF RS14830
gene id: 590998:CELF_RS14830
uniprot id: F4H8Q3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS15450
gene id: 590998:CELF_RS15450
uniprot id: F4GZ61
names: Similarity
messages: Belongs to the group II decarboxylase family.

590998:CELF RS08180
gene id: 590998:CELF_RS08180
uniprot id: F4H7S4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

590998:CELF RS05055
gene id: 590998:CELF_RS05055
uniprot id: F4H1X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

590998:CELF RS14315
gene id: 590998:CELF_RS14315
uniprot id: F4H7Z8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

590998:CELF RS18490
gene id: 590998:CELF_RS18490
uniprot id: F4H4H1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

590998:CELF RS04895
gene id: 590998:CELF_RS04895
uniprot id: F4H1D8
names: Similarity
messages: Belongs to the UPF0336 family.

590998:CELF RS10185
gene id: 590998:CELF_RS10185
uniprot id: F4H099
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07520
gene id: 590998:CELF_RS07520
uniprot id: F4H6J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

590998:CELF RS07695
gene id: 590998:CELF_RS07695
uniprot id: F4H730
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

590998:CELF RS17205
gene id: 590998:CELF_RS17205
uniprot id: F4H1V2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS16095
gene id: 590998:CELF_RS16095
uniprot id: F4H0D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

590998:CELF RS05440
gene id: 590998:CELF_RS05440
uniprot id: F4H2I9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

590998:CELF RS07680
gene id: 590998:CELF_RS07680
uniprot id: F4H727
names: Similarity
messages: Belongs to the FPG family.

590998:CELF RS08280
gene id: 590998:CELF_RS08280
uniprot id: F4H7U4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

590998:CELF RS02320
gene id: 590998:CELF_RS02320
uniprot id: F4H851
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

590998:CELF RS09420
gene id: 590998:CELF_RS09420
uniprot id: F4GZ03
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

590998:CELF RS17700
gene id: 590998:CELF_RS17700
uniprot id: F4H2Z6
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

590998:CELF RS11125
gene id: 590998:CELF_RS11125
uniprot id: F4H1N2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS06575
gene id: 590998:CELF_RS06575
uniprot id: F4H4W5
names: Similarity
messages: Belongs to the acylphosphatase family.

590998:CELF RS15035
gene id: 590998:CELF_RS15035
uniprot id: F4GYI4
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

590998:CELF RS04495
gene id: 590998:CELF_RS04495
uniprot id: F4H0Q6
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS18420
gene id: 590998:CELF_RS18420
uniprot id: F4H4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

590998:CELF RS15490
gene id: 590998:CELF_RS15490
uniprot id: F4GZ70
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

590998:CELF RS12880
gene id: 590998:CELF_RS12880
uniprot id: F4H570
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

590998:CELF RS09960
gene id: 590998:CELF_RS09960
uniprot id: F4GZQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS05460
gene id: 590998:CELF_RS05460
uniprot id: F4H2J3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

590998:CELF RS13150
gene id: 590998:CELF_RS13150
uniprot id: F4H601
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS19100
gene id: 590998:CELF_RS19100
uniprot id: F4H5G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

590998:CELF RS10880
gene id: 590998:CELF_RS10880
uniprot id: F4H1I2
names: Similarity
messages: Belongs to the thymidine kinase family.

590998:CELF RS05025
gene id: 590998:CELF_RS05025
uniprot id: F4H1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

590998:CELF RS11320
gene id: 590998:CELF_RS11320
uniprot id: F4H271
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

590998:CELF RS09935
gene id: 590998:CELF_RS09935
uniprot id: F4GZQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

590998:CELF RS20150
gene id: 590998:CELF_RS20150
uniprot id: F4H2M6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

590998:CELF RS05125
gene id: 590998:CELF_RS05125
uniprot id: F4H1Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

590998:CELF RS05865
gene id: 590998:CELF_RS05865
uniprot id: F4H379
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

590998:CELF RS04845
gene id: 590998:CELF_RS04845
uniprot id: F4H1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

590998:CELF RS14090
gene id: 590998:CELF_RS14090
uniprot id: F4H7F5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

590998:CELF RS10140
gene id: 590998:CELF_RS10140
uniprot id: F4H090
names: Similarity
messages: Belongs to the GSP E family.

590998:CELF RS06730
gene id: 590998:CELF_RS06730
uniprot id: F4H4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

590998:CELF RS09000
gene id: 590998:CELF_RS09000
uniprot id: F4GYC4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

590998:CELF RS08405
gene id: 590998:CELF_RS08405
uniprot id: F4H7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS01620
gene id: 590998:CELF_RS01620
uniprot id: F4H6W3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS15480
gene id: 590998:CELF_RS15480
uniprot id: F4GZ68
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

590998:CELF RS11600
gene id: 590998:CELF_RS11600
uniprot id: F4H2S4
names: Similarity
messages: Belongs to the manganese catalase family.

590998:CELF RS12710
gene id: 590998:CELF_RS12710
uniprot id: F4H536
names: Similarity
messages: Belongs to the ABC transporter superfamily.

590998:CELF RS14050
gene id: 590998:CELF_RS14050
uniprot id: F4H7E7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

590998:CELF RS01525
gene id: 590998:CELF_RS01525
uniprot id: F4H6E1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

590998:CELF RS10260
gene id: 590998:CELF_RS10260
uniprot id: F4H0B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

590998:CELF RS05790
gene id: 590998:CELF_RS05790
uniprot id: F4H364
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

590998:CELF RS02025
gene id: 590998:CELF_RS02025
uniprot id: F4H7J5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

590998:CELF RS19545
gene id: 590998:CELF_RS19545
uniprot id: F4H3H6
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS19500
gene id: 590998:CELF_RS19500
uniprot id: F4GZL9
names: Similarity
messages: Belongs to the UPF0749 family.

590998:CELF RS11090
gene id: 590998:CELF_RS11090
uniprot id: F4H1M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

590998:CELF RS09525
gene id: 590998:CELF_RS09525
uniprot id: F4GZ24
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

590998:CELF RS03300
gene id: 590998:CELF_RS03300
uniprot id: F4GYT2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

590998:CELF RS14055
gene id: 590998:CELF_RS14055
uniprot id: F4H7E8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

590998:CELF RS10090
gene id: 590998:CELF_RS10090
uniprot id: F4H080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

590998:CELF RS03345
gene id: 590998:CELF_RS03345
uniprot id: F4GYU1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

590998:CELF RS14850
gene id: 590998:CELF_RS14850
uniprot id: F4H8Q7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

590998:CELF RS08685
gene id: 590998:CELF_RS08685
uniprot id: F4H8H3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS11460
gene id: 590998:CELF_RS11460
uniprot id: F4H299
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

590998:CELF RS05750
gene id: 590998:CELF_RS05750
uniprot id: F4H2Q1
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09095
gene id: 590998:CELF_RS09095
uniprot id: F4GYE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS08770
gene id: 590998:CELF_RS08770
uniprot id: F4H8I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

590998:CELF RS14155
gene id: 590998:CELF_RS14155
uniprot id: F4H7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

590998:CELF RS02100
gene id: 590998:CELF_RS02100
uniprot id: F4H7L0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS12395
gene id: 590998:CELF_RS12395
uniprot id: F4H4A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

590998:CELF RS12135
gene id: 590998:CELF_RS12135
uniprot id: F4H3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

590998:CELF RS07700
gene id: 590998:CELF_RS07700
uniprot id: F4H731
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

590998:CELF RS11745
gene id: 590998:CELF_RS11745
uniprot id: F4H2V3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

590998:CELF RS19020
gene id: 590998:CELF_RS19020
uniprot id: F4H5E9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

590998:CELF RS09515
gene id: 590998:CELF_RS09515
uniprot id: F4GZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

590998:CELF RS00005
gene id: 590998:CELF_RS00005
uniprot id: F4H357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

590998:CELF RS05375
gene id: 590998:CELF_RS05375
uniprot id: F4H234
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

590998:CELF RS10195
gene id: 590998:CELF_RS10195
uniprot id: F4H0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS10245
gene id: 590998:CELF_RS10245
uniprot id: F4H0B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

590998:CELF RS08990
gene id: 590998:CELF_RS08990
uniprot id: F4GYC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

590998:CELF RS16860
gene id: 590998:CELF_RS16860
uniprot id: F4H1N4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

590998:CELF RS18505
gene id: 590998:CELF_RS18505
uniprot id: F4H4H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

590998:CELF RS02920
gene id: 590998:CELF_RS02920
uniprot id: F4GY58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

590998:CELF RS02975
gene id: 590998:CELF_RS02975
uniprot id: F4GY69
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

590998:CELF RS04395
gene id: 590998:CELF_RS04395
uniprot id: F4H0N7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

590998:CELF RS11055
gene id: 590998:CELF_RS11055
uniprot id: F4H1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

590998:CELF RS10985
gene id: 590998:CELF_RS10985
uniprot id: F4H1K3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS09630
gene id: 590998:CELF_RS09630
uniprot id: F4GZJ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS14400
gene id: 590998:CELF_RS14400
uniprot id: F4H815
names: Similarity
messages: Belongs to the phosphohexose mutase family.

590998:CELF RS02890
gene id: 590998:CELF_RS02890
uniprot id: F4GY52
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS09370
gene id: 590998:CELF_RS09370
uniprot id: F4GYZ3
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS16510
gene id: 590998:CELF_RS16510
uniprot id: F4H115
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

590998:CELF RS05000
gene id: 590998:CELF_RS05000
uniprot id: F4H1V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

590998:CELF RS08060
gene id: 590998:CELF_RS08060
uniprot id: F4H7Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

590998:CELF RS13430
gene id: 590998:CELF_RS13430
uniprot id: F4H6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

590998:CELF RS10130
gene id: 590998:CELF_RS10130
uniprot id: F4H088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

590998:CELF RS02775
gene id: 590998:CELF_RS02775
uniprot id: F4GY29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

590998:CELF RS07465
gene id: 590998:CELF_RS07465
uniprot id: F4H6I5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

590998:CELF RS07060
gene id: 590998:CELF_RS07060
uniprot id: F4H5T8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

590998:CELF RS00090
gene id: 590998:CELF_RS00090
uniprot id: F4H3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS15980
gene id: 590998:CELF_RS15980
uniprot id: F4GZW6
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS01695
gene id: 590998:CELF_RS01695
uniprot id: F4H6X8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS04730
gene id: 590998:CELF_RS04730
uniprot id: F4H1A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

590998:CELF RS05190
gene id: 590998:CELF_RS05190
uniprot id: F4H1Z7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

590998:CELF RS20850
gene id: 590998:CELF_RS20850
uniprot id: F4H3X2
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

590998:CELF RS01635
gene id: 590998:CELF_RS01635
uniprot id: F4H6W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

590998:CELF RS14185
gene id: 590998:CELF_RS14185
uniprot id: F4H7X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

590998:CELF RS12715
gene id: 590998:CELF_RS12715
uniprot id: F4H537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS14475
gene id: 590998:CELF_RS14475
uniprot id: F4H830
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

590998:CELF RS18415
gene id: 590998:CELF_RS18415
uniprot id: F4H4F5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

590998:CELF RS09415
gene id: 590998:CELF_RS09415
uniprot id: F4GZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

590998:CELF RS01865
gene id: 590998:CELF_RS01865
uniprot id: F4H712
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

590998:CELF RS13655
gene id: 590998:CELF_RS13655
uniprot id: F4H6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS17385
gene id: 590998:CELF_RS17385
uniprot id: F4H2D9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS14215
gene id: 590998:CELF_RS14215
uniprot id: F4H7Y0
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

590998:CELF RS10690
gene id: 590998:CELF_RS10690
uniprot id: F4H0Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

590998:CELF RS11900
gene id: 590998:CELF_RS11900
uniprot id: F4H3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

590998:CELF RS15425
gene id: 590998:CELF_RS15425
uniprot id: F4GZ56
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS03400
gene id: 590998:CELF_RS03400
uniprot id: F4GYV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS12780
gene id: 590998:CELF_RS12780
uniprot id: F4H550
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS13265
gene id: 590998:CELF_RS13265
uniprot id: F4H624
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

590998:CELF RS04435
gene id: 590998:CELF_RS04435
uniprot id: F4H0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS12935
gene id: 590998:CELF_RS12935
uniprot id: F4H582
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

590998:CELF RS19660
gene id: 590998:CELF_RS19660
uniprot id: F4GZ63
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

590998:CELF RS01625
gene id: 590998:CELF_RS01625
uniprot id: F4H6W4
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS13230
gene id: 590998:CELF_RS13230
uniprot id: F4H617
names: Similarity
messages: Belongs to the GSP E family.

590998:CELF RS06285
gene id: 590998:CELF_RS06285
uniprot id: F4H435
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

590998:CELF RS00735
gene id: 590998:CELF_RS00735
uniprot id: F4H4U4
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS12255
gene id: 590998:CELF_RS12255
uniprot id: F4H479
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

590998:CELF RS09405
gene id: 590998:CELF_RS09405
uniprot id: F4GZ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

590998:CELF RS13885
gene id: 590998:CELF_RS13885
uniprot id: F4H7B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS10065
gene id: 590998:CELF_RS10065
uniprot id: F4H075
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

590998:CELF RS14530
gene id: 590998:CELF_RS14530
uniprot id: F4H841
names: Similarity
messages: Belongs to the peptidase S1C family.

590998:CELF RS09990
gene id: 590998:CELF_RS09990
uniprot id: F4H060
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11015
gene id: 590998:CELF_RS11015
uniprot id: F4H1K9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS07580
gene id: 590998:CELF_RS07580
uniprot id: F4H6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

590998:CELF RS13600
gene id: 590998:CELF_RS13600
uniprot id: F4H6R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS03070
gene id: 590998:CELF_RS03070
uniprot id: F4GY89
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

590998:CELF RS15275
gene id: 590998:CELF_RS15275
uniprot id: F4GYM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

590998:CELF RS07455
gene id: 590998:CELF_RS07455
uniprot id: F4H6I3
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

590998:CELF RS14145
gene id: 590998:CELF_RS14145
uniprot id: F4H7G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

590998:CELF RS02885
gene id: 590998:CELF_RS02885
uniprot id: F4GY51
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

590998:CELF RS14440
gene id: 590998:CELF_RS14440
uniprot id: F4H823
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09280
gene id: 590998:CELF_RS09280
uniprot id: F4GYX5
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS12905
gene id: 590998:CELF_RS12905
uniprot id: F4H576
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

590998:CELF RS04760
gene id: 590998:CELF_RS04760
uniprot id: F4H1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

590998:CELF RS15655
gene id: 590998:CELF_RS15655
uniprot id: F4GZA2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

590998:CELF RS00270
gene id: 590998:CELF_RS00270
uniprot id: F4H3X9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS15770
gene id: 590998:CELF_RS15770
uniprot id: F4GZS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

590998:CELF RS15360
gene id: 590998:CELF_RS15360
uniprot id: F4GZ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

590998:CELF RS02030
gene id: 590998:CELF_RS02030
uniprot id: F4H7J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

590998:CELF RS07620
gene id: 590998:CELF_RS07620
uniprot id: F4H6L6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

590998:CELF RS10460
gene id: 590998:CELF_RS10460
uniprot id: F4H0V0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

590998:CELF RS12315
gene id: 590998:CELF_RS12315
uniprot id: F4H491
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

590998:CELF RS12885
gene id: 590998:CELF_RS12885
uniprot id: F4H571
names: Similarity
messages: Belongs to the citrate synthase family.

590998:CELF RS06455
gene id: 590998:CELF_RS06455
uniprot id: F4H469
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

590998:CELF RS17085
gene id: 590998:CELF_RS17085
uniprot id: F4H1T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

590998:CELF RS09750
gene id: 590998:CELF_RS09750
uniprot id: F4GZL4
names: Similarity
messages: Belongs to the DEAD box helicase family.

590998:CELF RS19145
gene id: 590998:CELF_RS19145
uniprot id: F4H5H2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS05130
gene id: 590998:CELF_RS05130
uniprot id: F4H1Y5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

590998:CELF RS08295
gene id: 590998:CELF_RS08295
uniprot id: F4H7U7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

590998:CELF RS11850
gene id: 590998:CELF_RS11850
uniprot id: F4H2X4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

590998:CELF RS03000
gene id: 590998:CELF_RS03000
uniprot id: F4GY75
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

590998:CELF RS04915
gene id: 590998:CELF_RS04915
uniprot id: F4H1E2
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS03525
gene id: 590998:CELF_RS03525
uniprot id: F4GZC5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

590998:CELF RS08720
gene id: 590998:CELF_RS08720
uniprot id: F4H8I0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

590998:CELF RS13155
gene id: 590998:CELF_RS13155
uniprot id: F4H602
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09940
gene id: 590998:CELF_RS09940
uniprot id: F4GZQ3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

590998:CELF RS11990
gene id: 590998:CELF_RS11990
uniprot id: F4H3F7
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS02845
gene id: 590998:CELF_RS02845
uniprot id: F4GY43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

590998:CELF RS03375
gene id: 590998:CELF_RS03375
uniprot id: F4GYU7
names: Similarity
messages: Belongs to the peptidase C40 family.

590998:CELF RS04280
gene id: 590998:CELF_RS04280
uniprot id: F4H0L5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

590998:CELF RS16615
gene id: 590998:CELF_RS16615
uniprot id: F4H136
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

590998:CELF RS12290
gene id: 590998:CELF_RS12290
uniprot id: F4H486
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

590998:CELF RS13075
gene id: 590998:CELF_RS13075
uniprot id: F4H5Y6
names: Similarity
messages: Belongs to the NodU/CmcH family.

590998:CELF RS08690
gene id: 590998:CELF_RS08690
uniprot id: F4H8H4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

590998:CELF RS10765
gene id: 590998:CELF_RS10765
uniprot id: F4H1F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

590998:CELF RS03160
gene id: 590998:CELF_RS03160
uniprot id: F4GYQ5
names: Subcellular Location Annotation
messages: Cytoplasm

590998:CELF RS17015
gene id: 590998:CELF_RS17015
uniprot id: F4H1R5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

590998:CELF RS13040
gene id: 590998:CELF_RS13040
uniprot id: F4H5X9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

590998:CELF RS16995
gene id: 590998:CELF_RS16995
uniprot id: F4H1R1
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS04680
gene id: 590998:CELF_RS04680
uniprot id: F4H196
names: Similarity
messages: Belongs to the isochorismate synthase family.

590998:CELF RS09425
gene id: 590998:CELF_RS09425
uniprot id: F4GZ04
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

590998:CELF RS12200
gene id: 590998:CELF_RS12200
uniprot id: F4H3J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS08455
gene id: 590998:CELF_RS08455
uniprot id: F4H8C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS13445
gene id: 590998:CELF_RS13445
uniprot id: F4H6N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

590998:CELF RS02525
gene id: 590998:CELF_RS02525
uniprot id: F4H890
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

590998:CELF RS00655
gene id: 590998:CELF_RS00655
uniprot id: F4H4S8
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05550
gene id: 590998:CELF_RS05550
uniprot id: F4H2L1
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS16365
gene id: 590998:CELF_RS16365
uniprot id: F4H0I6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

590998:CELF RS00480
gene id: 590998:CELF_RS00480
uniprot id: F4H4P4
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS12945
gene id: 590998:CELF_RS12945
uniprot id: F4H584
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

590998:CELF RS09470
gene id: 590998:CELF_RS09470
uniprot id: F4GZ13
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

590998:CELF RS15545
gene id: 590998:CELF_RS15545
uniprot id: F4GZ82
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

590998:CELF RS08945
gene id: 590998:CELF_RS08945
uniprot id: F4GYB3
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

590998:CELF RS16620
gene id: 590998:CELF_RS16620
uniprot id: F4H137
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

590998:CELF RS07285
gene id: 590998:CELF_RS07285
uniprot id: F4H6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS03210
gene id: 590998:CELF_RS03210
uniprot id: F4GYR5
names: Similarity
messages: Belongs to the WXG100 family.

590998:CELF RS12455
gene id: 590998:CELF_RS12455
uniprot id: F4H4B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

590998:CELF RS05605
gene id: 590998:CELF_RS05605
uniprot id: F4H2M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

590998:CELF RS12165
gene id: 590998:CELF_RS12165
uniprot id: F4H3J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

590998:CELF RS04200
gene id: 590998:CELF_RS04200
uniprot id: F4H051
names: Similarity
messages: Belongs to the malic enzymes family.

590998:CELF RS05680
gene id: 590998:CELF_RS05680
uniprot id: F4H2N7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

590998:CELF RS17075
gene id: 590998:CELF_RS17075
uniprot id: F4H1S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

590998:CELF RS05480
gene id: 590998:CELF_RS05480
uniprot id: F4H2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

590998:CELF RS01775
gene id: 590998:CELF_RS01775
uniprot id: F4H6Z4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

590998:CELF RS14740
gene id: 590998:CELF_RS14740
uniprot id: F4H8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS10965
gene id: 590998:CELF_RS10965
uniprot id: F4H1J9
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

590998:CELF RS16295
gene id: 590998:CELF_RS16295
uniprot id: F4H0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

590998:CELF RS02855
gene id: 590998:CELF_RS02855
uniprot id: F4GY45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

590998:CELF RS17445
gene id: 590998:CELF_RS17445
uniprot id: F4H2F1
names: Similarity
messages: Belongs to the FPG family.

590998:CELF RS20640
gene id: 590998:CELF_RS20640
uniprot id: F4H7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

590998:CELF RS04700
gene id: 590998:CELF_RS04700
uniprot id: F4H1A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

590998:CELF RS11430
gene id: 590998:CELF_RS11430
uniprot id: F4H293
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

590998:CELF RS04145
gene id: 590998:CELF_RS04145
uniprot id: F4H045
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

590998:CELF RS03465
gene id: 590998:CELF_RS03465
uniprot id: F4GZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

590998:CELF RS09995
gene id: 590998:CELF_RS09995
uniprot id: F4H061
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

590998:CELF RS06680
gene id: 590998:CELF_RS06680
uniprot id: F4H4Y6
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS04685
gene id: 590998:CELF_RS04685
uniprot id: F4H197
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

590998:CELF RS04630
gene id: 590998:CELF_RS04630
uniprot id: F4H185
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

590998:CELF RS00835
gene id: 590998:CELF_RS00835
uniprot id: F4H5J1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

590998:CELF RS03170
gene id: 590998:CELF_RS03170
uniprot id: F4GYQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

590998:CELF RS13555
gene id: 590998:CELF_RS13555
uniprot id: F4H6Q2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

590998:CELF RS10070
gene id: 590998:CELF_RS10070
uniprot id: F4H076
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

590998:CELF RS04610
gene id: 590998:CELF_RS04610
uniprot id: F4H0S9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05520
gene id: 590998:CELF_RS05520
uniprot id: F4H2K5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

590998:CELF RS10270
gene id: 590998:CELF_RS10270
uniprot id: F4H0B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

590998:CELF RS08305
gene id: 590998:CELF_RS08305
uniprot id: F4H7U9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

590998:CELF RS04725
gene id: 590998:CELF_RS04725
uniprot id: F4H1A5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

590998:CELF RS19305
gene id: 590998:CELF_RS19305
uniprot id: F4H6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

590998:CELF RS16440
gene id: 590998:CELF_RS16440
uniprot id: F4H0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

590998:CELF RS03685
gene id: 590998:CELF_RS03685
uniprot id: F4GZF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS10820
gene id: 590998:CELF_RS10820
uniprot id: F4H1H0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

590998:CELF RS12295
gene id: 590998:CELF_RS12295
uniprot id: F4H487
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

590998:CELF RS05450
gene id: 590998:CELF_RS05450
uniprot id: F4H2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

590998:CELF RS05385
gene id: 590998:CELF_RS05385
uniprot id: F4H2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

590998:CELF RS06920
gene id: 590998:CELF_RS06920
uniprot id: F4H5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

590998:CELF RS09710
gene id: 590998:CELF_RS09710
uniprot id: F4GZK6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

590998:CELF RS09865
gene id: 590998:CELF_RS09865
uniprot id: F4GZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

590998:CELF RS14455
gene id: 590998:CELF_RS14455
uniprot id: F4H826
names: Similarity
messages: Belongs to the BMP lipoprotein family.

590998:CELF RS03425
gene id: 590998:CELF_RS03425
uniprot id: F4GYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

590998:CELF RS06965
gene id: 590998:CELF_RS06965
uniprot id: F4H5R9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

590998:CELF RS01615
gene id: 590998:CELF_RS01615
uniprot id: F4H6W2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

590998:CELF RS02260
gene id: 590998:CELF_RS02260
uniprot id: F4H7N9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

590998:CELF RS13550
gene id: 590998:CELF_RS13550
uniprot id: F4H6Q1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

590998:CELF RS05885
gene id: 590998:CELF_RS05885
uniprot id: F4H383
names: Similarity
messages: Belongs to the Nudix hydrolase family.

590998:CELF RS20940
gene id: 590998:CELF_RS20940
uniprot id: F4H8R2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

590998:CELF RS14940
gene id: 590998:CELF_RS14940
uniprot id: F4GYG6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

590998:CELF RS10205
gene id: 590998:CELF_RS10205
uniprot id: F4H0A3
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

590998:CELF RS17235
gene id: 590998:CELF_RS17235
uniprot id: F4H2A8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

590998:CELF RS03270
gene id: 590998:CELF_RS03270
uniprot id: F4GYS6
names: Subcellular Location Annotation
messages: Cytoplasm

590998:CELF RS15390
gene id: 590998:CELF_RS15390
uniprot id: F4GZ50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

590998:CELF RS12655
gene id: 590998:CELF_RS12655
uniprot id: F4H525
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

590998:CELF RS12370
gene id: 590998:CELF_RS12370
uniprot id: F4H4A2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

590998:CELF RS16830
gene id: 590998:CELF_RS16830
uniprot id: F4H179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS07220
gene id: 590998:CELF_RS07220
uniprot id: F4H5W8
names: Subcellular Location Annotation
messages: Cell membrane

590998:CELF RS17315
gene id: 590998:CELF_RS17315
uniprot id: F4H2C6
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

590998:CELF RS15135
gene id: 590998:CELF_RS15135
uniprot id: F4GYK3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

590998:CELF RS16760
gene id: 590998:CELF_RS16760
uniprot id: F4H166
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

590998:CELF RS02870
gene id: 590998:CELF_RS02870
uniprot id: F4GY48
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS06220
gene id: 590998:CELF_RS06220
uniprot id: F4H422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS05210
gene id: 590998:CELF_RS05210
uniprot id: F4H201
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS14280
gene id: 590998:CELF_RS14280
uniprot id: F4H7Z1
names: Cofactor
messages: Can also use Mn(2+) ion.

590998:CELF RS16080
gene id: 590998:CELF_RS16080
uniprot id: F4GZY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

590998:CELF RS17870
gene id: 590998:CELF_RS17870
uniprot id: F4H329
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS14445
gene id: 590998:CELF_RS14445
uniprot id: F4H824
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS15230
gene id: 590998:CELF_RS15230
uniprot id: F4GYL7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

590998:CELF RS04890
gene id: 590998:CELF_RS04890
uniprot id: F4H1D7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

590998:CELF RS14210
gene id: 590998:CELF_RS14210
uniprot id: F4H7X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

590998:CELF RS07530
gene id: 590998:CELF_RS07530
uniprot id: F4H6J8
names: Similarity
messages: Belongs to the P(II) protein family.

590998:CELF RS04745
gene id: 590998:CELF_RS04745
uniprot id: F4H1A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

590998:CELF RS12355
gene id: 590998:CELF_RS12355
uniprot id: F4H499
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

590998:CELF RS19315
gene id: 590998:CELF_RS19315
uniprot id: F4H6V1
names: Similarity
messages: Belongs to the peptidase S8 family.

590998:CELF RS06080
gene id: 590998:CELF_RS06080
uniprot id: F4H3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

590998:CELF RS15460
gene id: 590998:CELF_RS15460
uniprot id: F4GZ64
names: Similarity
messages: Belongs to the IucA/IucC family.

590998:CELF RS09460
gene id: 590998:CELF_RS09460
uniprot id: F4GZ11
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS07420
gene id: 590998:CELF_RS07420
uniprot id: F4H6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

590998:CELF RS08340
gene id: 590998:CELF_RS08340
uniprot id: F4H7V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

590998:CELF RS07215
gene id: 590998:CELF_RS07215
uniprot id: F4H5W7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

590998:CELF RS08270
gene id: 590998:CELF_RS08270
uniprot id: F4H7U2
names: Similarity
messages: Belongs to the Fur family.

590998:CELF RS13260
gene id: 590998:CELF_RS13260
uniprot id: F4H623
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

590998:CELF RS14575
gene id: 590998:CELF_RS14575
uniprot id: F4H8K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

590998:CELF RS10255
gene id: 590998:CELF_RS10255
uniprot id: F4H0B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

590998:CELF RS14430
gene id: 590998:CELF_RS14430
uniprot id: F4H821
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

590998:CELF RS13365
gene id: 590998:CELF_RS13365
uniprot id: F4H644
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS16460
gene id: 590998:CELF_RS16460
uniprot id: F4H0K5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

590998:CELF RS04300
gene id: 590998:CELF_RS04300
uniprot id: F4H0L9
names: Similarity
messages: Belongs to the peptidase S33 family.

590998:CELF RS14840
gene id: 590998:CELF_RS14840
uniprot id: F4H8Q5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS17885
gene id: 590998:CELF_RS17885
uniprot id: F4H332
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09255
gene id: 590998:CELF_RS09255
uniprot id: F4GYX0
names: Similarity
messages: Belongs to the leucine-binding protein family.

590998:CELF RS14075
gene id: 590998:CELF_RS14075
uniprot id: F4H7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS19045
gene id: 590998:CELF_RS19045
uniprot id: F4H5F4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS05075
gene id: 590998:CELF_RS05075
uniprot id: F4H1X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

590998:CELF RS18455
gene id: 590998:CELF_RS18455
uniprot id: F4H4G3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

590998:CELF RS11075
gene id: 590998:CELF_RS11075
uniprot id: F4H1M1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

590998:CELF RS01805
gene id: 590998:CELF_RS01805
uniprot id: F4H700
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS03485
gene id: 590998:CELF_RS03485
uniprot id: F4GZB7
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS11035
gene id: 590998:CELF_RS11035
uniprot id: F4H1L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

590998:CELF RS13220
gene id: 590998:CELF_RS13220
uniprot id: F4H615
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS04965
gene id: 590998:CELF_RS04965
uniprot id: F4H1F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

590998:CELF RS11135
gene id: 590998:CELF_RS11135
uniprot id: F4H236
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

590998:CELF RS04480
gene id: 590998:CELF_RS04480
uniprot id: F4H0Q4
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07335
gene id: 590998:CELF_RS07335
uniprot id: F4H6F8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

590998:CELF RS16530
gene id: 590998:CELF_RS16530
uniprot id: F4H119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS13770
gene id: 590998:CELF_RS13770
uniprot id: F4H6U4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

590998:CELF RS12940
gene id: 590998:CELF_RS12940
uniprot id: F4H583
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

590998:CELF RS16000
gene id: 590998:CELF_RS16000
uniprot id: F4GZX0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

590998:CELF RS06185
gene id: 590998:CELF_RS06185
uniprot id: F4H415
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

590998:CELF RS14870
gene id: 590998:CELF_RS14870
uniprot id: F4H8R1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

590998:CELF RS06840
gene id: 590998:CELF_RS06840
uniprot id: F4H519
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

590998:CELF RS08360
gene id: 590998:CELF_RS08360
uniprot id: F4H7W0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

590998:CELF RS08205
gene id: 590998:CELF_RS08205
uniprot id: F4H7S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

590998:CELF RS08485
gene id: 590998:CELF_RS08485
uniprot id: F4H8D3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11225
gene id: 590998:CELF_RS11225
uniprot id: F4H254
names: Similarity
messages: Belongs to the glutamine synthetase family.

590998:CELF RS08165
gene id: 590998:CELF_RS08165
uniprot id: F4H7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

590998:CELF RS10250
gene id: 590998:CELF_RS10250
uniprot id: F4H0B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

590998:CELF RS07710
gene id: 590998:CELF_RS07710
uniprot id: F4H732
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

590998:CELF RS07915
gene id: 590998:CELF_RS07915
uniprot id: F4H773
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

590998:CELF RS01660
gene id: 590998:CELF_RS01660
uniprot id: F4H6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS10675
gene id: 590998:CELF_RS10675
uniprot id: F4H0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

590998:CELF RS08555
gene id: 590998:CELF_RS08555
uniprot id: F4H8E7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

590998:CELF RS09365
gene id: 590998:CELF_RS09365
uniprot id: F4GYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

590998:CELF RS19175
gene id: 590998:CELF_RS19175
uniprot id: F4H651
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS17525
gene id: 590998:CELF_RS17525
uniprot id: F4H2G5
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS13800
gene id: 590998:CELF_RS13800
uniprot id: F4H7A0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

590998:CELF RS10330
gene id: 590998:CELF_RS10330
uniprot id: F4H0C7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS09325
gene id: 590998:CELF_RS09325
uniprot id: F4GYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

590998:CELF RS03430
gene id: 590998:CELF_RS03430
uniprot id: F4GYV8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

590998:CELF RS09645
gene id: 590998:CELF_RS09645
uniprot id: F4GZJ3
names: Similarity
messages: Belongs to the pirin family.

590998:CELF RS06280
gene id: 590998:CELF_RS06280
uniprot id: F4H434
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

590998:CELF RS14220
gene id: 590998:CELF_RS14220
uniprot id: F4H7Y1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

590998:CELF RS00545
gene id: 590998:CELF_RS00545
uniprot id: F4H4Q7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

590998:CELF RS06765
gene id: 590998:CELF_RS06765
uniprot id: F4H503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS15270
gene id: 590998:CELF_RS15270
uniprot id: F4GYM5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

590998:CELF RS13135
gene id: 590998:CELF_RS13135
uniprot id: F4H5Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

590998:CELF RS01455
gene id: 590998:CELF_RS01455
uniprot id: F4H6C7
names: Similarity
messages: Belongs to the group II decarboxylase family.

590998:CELF RS06270
gene id: 590998:CELF_RS06270
uniprot id: F4H432
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

590998:CELF RS16885
gene id: 590998:CELF_RS16885
uniprot id: F4H1N9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

590998:CELF RS16785
gene id: 590998:CELF_RS16785
uniprot id: F4H171
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

590998:CELF RS14810
gene id: 590998:CELF_RS14810
uniprot id: F4H8P9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS03385
gene id: 590998:CELF_RS03385
uniprot id: F4GYU9
names: Similarity
messages: Belongs to the FlgD family.

590998:CELF RS15745
gene id: 590998:CELF_RS15745
uniprot id: F4GZR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

590998:CELF RS09135
gene id: 590998:CELF_RS09135
uniprot id: F4GYE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

590998:CELF RS06465
gene id: 590998:CELF_RS06465
uniprot id: F4H471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS12695
gene id: 590998:CELF_RS12695
uniprot id: F4H533
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

590998:CELF RS19475
gene id: 590998:CELF_RS19475
uniprot id: F4H8I4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

590998:CELF RS19295
gene id: 590998:CELF_RS19295
uniprot id: F4H667
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

590998:CELF RS00770
gene id: 590998:CELF_RS00770
uniprot id: F4H5H7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS04530
gene id: 590998:CELF_RS04530
uniprot id: F4H0R3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

590998:CELF RS10945
gene id: 590998:CELF_RS10945
uniprot id: F4H1J5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

590998:CELF RS08365
gene id: 590998:CELF_RS08365
uniprot id: F4H7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

590998:CELF RS05010
gene id: 590998:CELF_RS05010
uniprot id: F4H1W1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

590998:CELF RS07255
gene id: 590998:CELF_RS07255
uniprot id: F4H6E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

590998:CELF RS19110
gene id: 590998:CELF_RS19110
uniprot id: F4H5G6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

590998:CELF RS16670
gene id: 590998:CELF_RS16670
uniprot id: F4H147
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07910
gene id: 590998:CELF_RS07910
uniprot id: F4H772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

590998:CELF RS12795
gene id: 590998:CELF_RS12795
uniprot id: F4H553
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

590998:CELF RS05180
gene id: 590998:CELF_RS05180
uniprot id: F4H1Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

590998:CELF RS07755
gene id: 590998:CELF_RS07755
uniprot id: F4H741
names: Similarity
messages: Belongs to the peptidase M16 family.

590998:CELF RS09360
gene id: 590998:CELF_RS09360
uniprot id: F4GYZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

590998:CELF RS07945
gene id: 590998:CELF_RS07945
uniprot id: F4H779
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

590998:CELF RS08375
gene id: 590998:CELF_RS08375
uniprot id: F4H7W3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS08045
gene id: 590998:CELF_RS08045
uniprot id: F4H7P8
names: Subcellular Location Annotation
messages: Cytoplasm

590998:CELF RS13890
gene id: 590998:CELF_RS13890
uniprot id: F4H7B8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

590998:CELF RS20635
gene id: 590998:CELF_RS20635
uniprot id: F4H7R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11530
gene id: 590998:CELF_RS11530
uniprot id: F4H2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS08505
gene id: 590998:CELF_RS08505
uniprot id: F4H8D7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

590998:CELF RS05410
gene id: 590998:CELF_RS05410
uniprot id: F4H2I3
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

590998:CELF RS02955
gene id: 590998:CELF_RS02955
uniprot id: F4GY65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

590998:CELF RS19105
gene id: 590998:CELF_RS19105
uniprot id: F4H5G5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS16825
gene id: 590998:CELF_RS16825
uniprot id: F4H178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS07505
gene id: 590998:CELF_RS07505
uniprot id: F4H6J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

590998:CELF RS16850
gene id: 590998:CELF_RS16850
uniprot id: F4H183
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS11860
gene id: 590998:CELF_RS11860
uniprot id: F4H2X6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

590998:CELF RS17655
gene id: 590998:CELF_RS17655
uniprot id: F4H2Y7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS12950
gene id: 590998:CELF_RS12950
uniprot id: F4H585
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

590998:CELF RS07810
gene id: 590998:CELF_RS07810
uniprot id: F4H752
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

590998:CELF RS07525
gene id: 590998:CELF_RS07525
uniprot id: F4H6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

590998:CELF RS00370
gene id: 590998:CELF_RS00370
uniprot id: F4H3Z9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

590998:CELF RS09430
gene id: 590998:CELF_RS09430
uniprot id: F4GZ05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

590998:CELF RS13645
gene id: 590998:CELF_RS13645
uniprot id: F4H6S0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

590998:CELF RS10570
gene id: 590998:CELF_RS10570
uniprot id: F4H0X2
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

590998:CELF RS09060
gene id: 590998:CELF_RS09060
uniprot id: F4GYD4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

590998:CELF RS12650
gene id: 590998:CELF_RS12650
uniprot id: F4H524
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

590998:CELF RS11455
gene id: 590998:CELF_RS11455
uniprot id: F4H298
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

590998:CELF RS08155
gene id: 590998:CELF_RS08155
uniprot id: F4H7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

590998:CELF RS06180
gene id: 590998:CELF_RS06180
uniprot id: F4H414
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

590998:CELF RS04995
gene id: 590998:CELF_RS04995
uniprot id: F4H1V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

590998:CELF RS00125
gene id: 590998:CELF_RS00125
uniprot id: F4H3V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

590998:CELF RS18000
gene id: 590998:CELF_RS18000
uniprot id: F4H353
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS08560
gene id: 590998:CELF_RS08560
uniprot id: F4H8E8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

590998:CELF RS08980
gene id: 590998:CELF_RS08980
uniprot id: F4GYC0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

590998:CELF RS13780
gene id: 590998:CELF_RS13780
uniprot id: F4H796
names: Similarity
messages: Belongs to the DNA photolyase family.

590998:CELF RS16055
gene id: 590998:CELF_RS16055
uniprot id: F4GZX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

590998:CELF RS08890
gene id: 590998:CELF_RS08890
uniprot id: F4GYA3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

590998:CELF RS05115
gene id: 590998:CELF_RS05115
uniprot id: F4H1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

590998:CELF RS05835
gene id: 590998:CELF_RS05835
uniprot id: F4H373
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

590998:CELF RS17450
gene id: 590998:CELF_RS17450
uniprot id: F4H2F2
names: Similarity
messages: Belongs to the AAA ATPase family.

590998:CELF RS18125
gene id: 590998:CELF_RS18125
uniprot id: F4H3M9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

590998:CELF RS05370
gene id: 590998:CELF_RS05370
uniprot id: F4H233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS11045
gene id: 590998:CELF_RS11045
uniprot id: F4H1L5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

590998:CELF RS05085
gene id: 590998:CELF_RS05085
uniprot id: F4H1X6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

590998:CELF RS14165
gene id: 590998:CELF_RS14165
uniprot id: F4H7X0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09045
gene id: 590998:CELF_RS09045
uniprot id: F4GYD3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

590998:CELF RS08665
gene id: 590998:CELF_RS08665
uniprot id: F4H8G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

590998:CELF RS01795
gene id: 590998:CELF_RS01795
uniprot id: F4H6Z8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS19245
gene id: 590998:CELF_RS19245
uniprot id: F4H664
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

590998:CELF RS19230
gene id: 590998:CELF_RS19230
uniprot id: F4H661
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

590998:CELF RS05895
gene id: 590998:CELF_RS05895
uniprot id: F4H385
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

590998:CELF RS10595
gene id: 590998:CELF_RS10595
uniprot id: F4H0X7
names: Subcellular Location Annotation
messages: Cell membrane

590998:CELF RS10325
gene id: 590998:CELF_RS10325
uniprot id: F4H0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

590998:CELF RS05470
gene id: 590998:CELF_RS05470
uniprot id: F4H2J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

590998:CELF RS19375
gene id: 590998:CELF_RS19375
uniprot id: F4H025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

590998:CELF RS05110
gene id: 590998:CELF_RS05110
uniprot id: F4H1Y1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

590998:CELF RS07630
gene id: 590998:CELF_RS07630
uniprot id: F4H6L8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS10825
gene id: 590998:CELF_RS10825
uniprot id: F4H1H1
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS18945
gene id: 590998:CELF_RS18945
uniprot id: F4H5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS00935
gene id: 590998:CELF_RS00935
uniprot id: F4H5L0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

590998:CELF RS13225
gene id: 590998:CELF_RS13225
uniprot id: F4H616
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS19215
gene id: 590998:CELF_RS19215
uniprot id: F4H659
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

590998:CELF RS03235
gene id: 590998:CELF_RS03235
uniprot id: F4GYS0
names: Similarity
messages: Belongs to the PspA/IM30 family.

590998:CELF RS03690
gene id: 590998:CELF_RS03690
uniprot id: F4GZF7
names: Similarity
messages: Belongs to the peptidase C40 family.

590998:CELF RS04290
gene id: 590998:CELF_RS04290
uniprot id: F4H0L7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS09970
gene id: 590998:CELF_RS09970
uniprot id: F4GZQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

590998:CELF RS08540
gene id: 590998:CELF_RS08540
uniprot id: F4H8E4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

590998:CELF RS10025
gene id: 590998:CELF_RS10025
uniprot id: F4H067
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS04695
gene id: 590998:CELF_RS04695
uniprot id: F4H199
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

590998:CELF RS12745
gene id: 590998:CELF_RS12745
uniprot id: F4H543
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

590998:CELF RS12590
gene id: 590998:CELF_RS12590
uniprot id: F4H4E3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

590998:CELF RS05045
gene id: 590998:CELF_RS05045
uniprot id: F4H1W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

590998:CELF RS07000
gene id: 590998:CELF_RS07000
uniprot id: F4H5S6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

590998:CELF RS08755
gene id: 590998:CELF_RS08755
uniprot id: F4H8I6
names: Similarity
messages: Belongs to the UPF0098 family.

590998:CELF RS01000
gene id: 590998:CELF_RS01000
uniprot id: F4H5M3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS12235
gene id: 590998:CELF_RS12235
uniprot id: F4H3K6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

590998:CELF RS14585
gene id: 590998:CELF_RS14585
uniprot id: F4H8K6
names: Similarity
messages: Belongs to the citrate synthase family.

590998:CELF RS13805
gene id: 590998:CELF_RS13805
uniprot id: F4H7A1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

590998:CELF RS00435
gene id: 590998:CELF_RS00435
uniprot id: F4H4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS07895
gene id: 590998:CELF_RS07895
uniprot id: F4H769
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

590998:CELF RS01120
gene id: 590998:CELF_RS01120
uniprot id: F4H5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

590998:CELF RS05630
gene id: 590998:CELF_RS05630
uniprot id: F4H2M7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

590998:CELF RS13725
gene id: 590998:CELF_RS13725
uniprot id: F4H6T6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS06695
gene id: 590998:CELF_RS06695
uniprot id: F4H4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

590998:CELF RS08000
gene id: 590998:CELF_RS08000
uniprot id: F4H790
names: Similarity
messages: Belongs to the peptidase S9C family.

590998:CELF RS11040
gene id: 590998:CELF_RS11040
uniprot id: F4H1L4
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS03320
gene id: 590998:CELF_RS03320
uniprot id: F4GYT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

590998:CELF RS17245
gene id: 590998:CELF_RS17245
uniprot id: F4H2B1
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

590998:CELF RS03180
gene id: 590998:CELF_RS03180
uniprot id: F4GYQ9
names: Similarity
messages: Belongs to the peptidase S66 family.

590998:CELF RS19405
gene id: 590998:CELF_RS19405
uniprot id: F4H1C3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS14140
gene id: 590998:CELF_RS14140
uniprot id: F4H7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

590998:CELF RS03450
gene id: 590998:CELF_RS03450
uniprot id: F4GYW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

590998:CELF RS14590
gene id: 590998:CELF_RS14590
uniprot id: F4H8K7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS10180
gene id: 590998:CELF_RS10180
uniprot id: F4H098
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

590998:CELF RS08230
gene id: 590998:CELF_RS08230
uniprot id: F4H7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

590998:CELF RS07585
gene id: 590998:CELF_RS07585
uniprot id: F4H6K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

590998:CELF RS05995
gene id: 590998:CELF_RS05995
uniprot id: F4H3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS02515
gene id: 590998:CELF_RS02515
uniprot id: F4H888
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

590998:CELF RS13650
gene id: 590998:CELF_RS13650
uniprot id: F4H6S1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

590998:CELF RS05060
gene id: 590998:CELF_RS05060
uniprot id: F4H1X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

590998:CELF RS05905
gene id: 590998:CELF_RS05905
uniprot id: F4H387
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

590998:CELF RS07750
gene id: 590998:CELF_RS07750
uniprot id: F4H740
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

590998:CELF RS11205
gene id: 590998:CELF_RS11205
uniprot id: F4H250
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

590998:CELF RS17690
gene id: 590998:CELF_RS17690
uniprot id: F4H2Z4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

590998:CELF RS09330
gene id: 590998:CELF_RS09330
uniprot id: F4GYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

590998:CELF RS05140
gene id: 590998:CELF_RS05140
uniprot id: F4H1Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

590998:CELF RS07950
gene id: 590998:CELF_RS07950
uniprot id: F4H780
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS00360
gene id: 590998:CELF_RS00360
uniprot id: F4H3Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

590998:CELF RS07595
gene id: 590998:CELF_RS07595
uniprot id: F4H6L1
names: Similarity
messages: Belongs to the UPF0102 family.

590998:CELF RS16255
gene id: 590998:CELF_RS16255
uniprot id: F4H0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

590998:CELF RS04450
gene id: 590998:CELF_RS04450
uniprot id: F4H0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS13360
gene id: 590998:CELF_RS13360
uniprot id: F4H643
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05645
gene id: 590998:CELF_RS05645
uniprot id: F4H2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

590998:CELF RS12730
gene id: 590998:CELF_RS12730
uniprot id: F4H540
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

590998:CELF RS09770
gene id: 590998:CELF_RS09770
uniprot id: F4GZL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

590998:CELF RS04655
gene id: 590998:CELF_RS04655
uniprot id: F4H191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

590998:CELF RS13055
gene id: 590998:CELF_RS13055
uniprot id: F4H5Y2
names: Similarity
messages: Belongs to the peptidase S1C family.

590998:CELF RS04465
gene id: 590998:CELF_RS04465
uniprot id: F4H0Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

590998:CELF RS09920
gene id: 590998:CELF_RS09920
uniprot id: F4GZP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

590998:CELF RS17855
gene id: 590998:CELF_RS17855
uniprot id: F4H327
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

590998:CELF RS17150
gene id: 590998:CELF_RS17150
uniprot id: P50899
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 48 (cellulase L) family.
messages: Hydrolyzes cellohexaose to a mixture of cellotetraose, cellotriose and cellobiose, with only a trace of glucose. It hydrolyzed cellopentaose to cellotriose and cellobiose, and cellotetraose to cellobiose, but it did not hydrolyze cellotriose. Has also weak endoglucanase activity. Hydrolyzes glucosidic bonds with inversion of anomeric configuration.

590998:CELF RS03835
gene id: 590998:CELF_RS03835
uniprot id: F4GZI5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

590998:CELF RS10015
gene id: 590998:CELF_RS10015
uniprot id: F4H065
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

590998:CELF RS09600
gene id: 590998:CELF_RS09600
uniprot id: F4GZ39
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS08210
gene id: 590998:CELF_RS08210
uniprot id: F4H7T0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

590998:CELF RS19520
gene id: 590998:CELF_RS19520
uniprot id: F4H257
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS06885
gene id: 590998:CELF_RS06885
uniprot id: F4H5Q6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

590998:CELF RS19125
gene id: 590998:CELF_RS19125
uniprot id: F4H5G9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

590998:CELF RS09975
gene id: 590998:CELF_RS09975
uniprot id: F4GZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

590998:CELF RS04755
gene id: 590998:CELF_RS04755
uniprot id: F4H1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

590998:CELF RS09845
gene id: 590998:CELF_RS09845
uniprot id: F4GZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

590998:CELF RS10590
gene id: 590998:CELF_RS10590
uniprot id: F4H0X6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

590998:CELF RS13245
gene id: 590998:CELF_RS13245
uniprot id: F4H620
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

590998:CELF RS10770
gene id: 590998:CELF_RS10770
uniprot id: F4H1G0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS03315
gene id: 590998:CELF_RS03315
uniprot id: F4GYT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

590998:CELF RS05105
gene id: 590998:CELF_RS05105
uniprot id: F4H1Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

590998:CELF RS14705
gene id: 590998:CELF_RS14705
uniprot id: F4H8N0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

590998:CELF RS12300
gene id: 590998:CELF_RS12300
uniprot id: F4H488
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

590998:CELF RS05145
gene id: 590998:CELF_RS05145
uniprot id: F4H1Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

590998:CELF RS15455
gene id: 590998:CELF_RS15455
uniprot id: F4GZ62
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

590998:CELF RS02380
gene id: 590998:CELF_RS02380
uniprot id: F4H863
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

590998:CELF RS01180
gene id: 590998:CELF_RS01180
uniprot id: F4H671
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

590998:CELF RS05170
gene id: 590998:CELF_RS05170
uniprot id: F4H1Z3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

590998:CELF RS14890
gene id: 590998:CELF_RS14890
uniprot id: F4H8R5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

590998:CELF RS18250
gene id: 590998:CELF_RS18250
uniprot id: F4H3Q2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

590998:CELF RS02865
gene id: 590998:CELF_RS02865
uniprot id: F4GY47
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

590998:CELF RS00750
gene id: 590998:CELF_RS00750
uniprot id: F4H4U7
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07800
gene id: 590998:CELF_RS07800
uniprot id: F4H750
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

590998:CELF RS05970
gene id: 590998:CELF_RS05970
uniprot id: F4H3A0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

590998:CELF RS00020
gene id: 590998:CELF_RS00020
uniprot id: F4H3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

590998:CELF RS07325
gene id: 590998:CELF_RS07325
uniprot id: F4H6F6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS15755
gene id: 590998:CELF_RS15755
uniprot id: F4GZS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

590998:CELF RS02785
gene id: 590998:CELF_RS02785
uniprot id: F4GY31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS07790
gene id: 590998:CELF_RS07790
uniprot id: F4H748
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

590998:CELF RS14180
gene id: 590998:CELF_RS14180
uniprot id: F4H7X3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

590998:CELF RS03650
gene id: 590998:CELF_RS03650
uniprot id: F4GZE9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

590998:CELF RS17210
gene id: 590998:CELF_RS17210
uniprot id: F4H1V3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

590998:CELF RS08450
gene id: 590998:CELF_RS08450
uniprot id: F4H8C6
names: Similarity
messages: Belongs to the TlyA family.

590998:CELF RS01910
gene id: 590998:CELF_RS01910
uniprot id: F4H7H2
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS03940
gene id: 590998:CELF_RS03940
uniprot id: F4H006
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

590998:CELF RS07140
gene id: 590998:CELF_RS07140
uniprot id: F4H5V4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

590998:CELF RS07460
gene id: 590998:CELF_RS07460
uniprot id: F4H6I4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

590998:CELF RS05040
gene id: 590998:CELF_RS05040
uniprot id: F4H1W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

590998:CELF RS14485
gene id: 590998:CELF_RS14485
uniprot id: F4H832
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

590998:CELF RS17600
gene id: 590998:CELF_RS17600
uniprot id: F4H2H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

590998:CELF RS17995
gene id: 590998:CELF_RS17995
uniprot id: F4H352
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS15130
gene id: 590998:CELF_RS15130
uniprot id: F4GYK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

590998:CELF RS09945
gene id: 590998:CELF_RS09945
uniprot id: F4GZQ4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

590998:CELF RS02335
gene id: 590998:CELF_RS02335
uniprot id: F4H854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS03910
gene id: 590998:CELF_RS03910
uniprot id: F4H000
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

590998:CELF RS11315
gene id: 590998:CELF_RS11315
uniprot id: F4H270
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11030
gene id: 590998:CELF_RS11030
uniprot id: F4H1L2
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

590998:CELF RS13285
gene id: 590998:CELF_RS13285
uniprot id: F4H628
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

590998:CELF RS01945
gene id: 590998:CELF_RS01945
uniprot id: F4H7H9
names: Similarity
messages: Belongs to the peptidase S33 family.

590998:CELF RS10265
gene id: 590998:CELF_RS10265
uniprot id: F4H0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

590998:CELF RS14135
gene id: 590998:CELF_RS14135
uniprot id: F4H7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

590998:CELF RS17220
gene id: 590998:CELF_RS17220
uniprot id: F4H1V5
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS08480
gene id: 590998:CELF_RS08480
uniprot id: F4H8D2
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS16455
gene id: 590998:CELF_RS16455
uniprot id: F4H0K4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS08765
gene id: 590998:CELF_RS08765
uniprot id: F4H8I8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

590998:CELF RS01275
gene id: 590998:CELF_RS01275
uniprot id: F4H690
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07345
gene id: 590998:CELF_RS07345
uniprot id: F4H6G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS15595
gene id: 590998:CELF_RS15595
uniprot id: F4GZ91
names: Similarity
messages: Belongs to the UDPGP type 1 family.

590998:CELF RS09900
gene id: 590998:CELF_RS09900
uniprot id: F4GZP5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

590998:CELF RS04800
gene id: 590998:CELF_RS04800
uniprot id: F4H1C1
names: Similarity
messages: Belongs to the WXG100 family.

590998:CELF RS09435
gene id: 590998:CELF_RS09435
uniprot id: F4GZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

590998:CELF RS08910
gene id: 590998:CELF_RS08910
uniprot id: F4GYA7
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS04835
gene id: 590998:CELF_RS04835
uniprot id: F4H1C9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

590998:CELF RS05675
gene id: 590998:CELF_RS05675
uniprot id: F4H2N6
names: Similarity
messages: Belongs to the peptidase S1 family.

590998:CELF RS04375
gene id: 590998:CELF_RS04375
uniprot id: F4H0N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

590998:CELF RS21045
gene id: 590998:CELF_RS21045
uniprot id: F4H7J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the faeC family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.
messages: Secreted

590998:CELF RS08085
gene id: 590998:CELF_RS08085
uniprot id: F4H7Q5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

590998:CELF RS09760
gene id: 590998:CELF_RS09760
uniprot id: F4GZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

590998:CELF RS18805
gene id: 590998:CELF_RS18805
uniprot id: F4H5A4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

590998:CELF RS11705
gene id: 590998:CELF_RS11705
uniprot id: F4H2U5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

590998:CELF RS05185
gene id: 590998:CELF_RS05185
uniprot id: F4H1Z6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

590998:CELF RS12870
gene id: 590998:CELF_RS12870
uniprot id: F4H568
names: Similarity
messages: Belongs to the alkaline phosphatase family.

590998:CELF RS18770
gene id: 590998:CELF_RS18770
uniprot id: F4H4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS14355
gene id: 590998:CELF_RS14355
uniprot id: F4H806
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

590998:CELF RS19350
gene id: 590998:CELF_RS19350
uniprot id: F4H8A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

590998:CELF RS02755
gene id: 590998:CELF_RS02755
uniprot id: F4GY25
names: Similarity
messages: Belongs to the peptidase C40 family.

590998:CELF RS06470
gene id: 590998:CELF_RS06470
uniprot id: F4H472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS04340
gene id: 590998:CELF_RS04340
uniprot id: F4H0M7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

590998:CELF RS10160
gene id: 590998:CELF_RS10160
uniprot id: F4H094
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

590998:CELF RS07925
gene id: 590998:CELF_RS07925
uniprot id: F4H775
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

590998:CELF RS04720
gene id: 590998:CELF_RS04720
uniprot id: F4H1A4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

590998:CELF RS06820
gene id: 590998:CELF_RS06820
uniprot id: F4H515
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

590998:CELF RS04855
gene id: 590998:CELF_RS04855
uniprot id: F4H1D3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

590998:CELF RS16250
gene id: 590998:CELF_RS16250
uniprot id: F4H0G4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

590998:CELF RS02445
gene id: 590998:CELF_RS02445
uniprot id: F4H875
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

590998:CELF RS15400
gene id: 590998:CELF_RS15400
uniprot id: F4GZ52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

590998:CELF RS15095
gene id: 590998:CELF_RS15095
uniprot id: F4GYJ5
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05430
gene id: 590998:CELF_RS05430
uniprot id: F4H2I7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

590998:CELF RS02440
gene id: 590998:CELF_RS02440
uniprot id: F4H874
names: Similarity
messages: Belongs to the thioredoxin family.

590998:CELF RS13740
gene id: 590998:CELF_RS13740
uniprot id: F4H6T8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS18020
gene id: 590998:CELF_RS18020
uniprot id: F4H3K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS02230
gene id: 590998:CELF_RS02230
uniprot id: F4H7N4
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS08510
gene id: 590998:CELF_RS08510
uniprot id: F4H8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS07605
gene id: 590998:CELF_RS07605
uniprot id: F4H6L3
names: Similarity
messages: Belongs to the DprA/Smf family.

590998:CELF RS05405
gene id: 590998:CELF_RS05405
uniprot id: F4H2I2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

590998:CELF RS07665
gene id: 590998:CELF_RS07665
uniprot id: F4H724
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

590998:CELF RS13945
gene id: 590998:CELF_RS13945
uniprot id: F4H7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS18820
gene id: 590998:CELF_RS18820
uniprot id: F4H5A7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

590998:CELF RS15015
gene id: 590998:CELF_RS15015
uniprot id: F4GYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS08195
gene id: 590998:CELF_RS08195
uniprot id: F4H7S7
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS13975
gene id: 590998:CELF_RS13975
uniprot id: F4H7D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

590998:CELF RS02760
gene id: 590998:CELF_RS02760
uniprot id: F4GY26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

590998:CELF RS11555
gene id: 590998:CELF_RS11555
uniprot id: F4H2R5
names: Similarity
messages: Belongs to the CsoR family.

590998:CELF RS19185
gene id: 590998:CELF_RS19185
uniprot id: F4H653
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

590998:CELF RS17750
gene id: 590998:CELF_RS17750
uniprot id: F4H306
names: Similarity
messages: Belongs to the Nth/MutY family.

590998:CELF RS04305
gene id: 590998:CELF_RS04305
uniprot id: F4H0M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

590998:CELF RS15555
gene id: 590998:CELF_RS15555
uniprot id: F4GZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

590998:CELF RS08105
gene id: 590998:CELF_RS08105
uniprot id: F4H7Q9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11065
gene id: 590998:CELF_RS11065
uniprot id: F4H1L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

590998:CELF RS18140
gene id: 590998:CELF_RS18140
uniprot id: F4H3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

590998:CELF RS11525
gene id: 590998:CELF_RS11525
uniprot id: F4H2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS18670
gene id: 590998:CELF_RS18670
uniprot id: F4H4K8
names: Similarity
messages: Belongs to the peptidase S33 family.

590998:CELF RS08385
gene id: 590998:CELF_RS08385
uniprot id: F4H7W5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS13905
gene id: 590998:CELF_RS13905
uniprot id: F4H7C1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

590998:CELF RS13110
gene id: 590998:CELF_RS13110
uniprot id: F4H5Z3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

590998:CELF RS06995
gene id: 590998:CELF_RS06995
uniprot id: F4H5S5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

590998:CELF RS15715
gene id: 590998:CELF_RS15715
uniprot id: F4GZR4
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS02675
gene id: 590998:CELF_RS02675
uniprot id: F4H8C0
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

590998:CELF RS14845
gene id: 590998:CELF_RS14845
uniprot id: F4H8Q6
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07510
gene id: 590998:CELF_RS07510
uniprot id: F4H6J4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

590998:CELF RS03350
gene id: 590998:CELF_RS03350
uniprot id: F4GYU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

590998:CELF RS10005
gene id: 590998:CELF_RS10005
uniprot id: F4H063
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

590998:CELF RS09075
gene id: 590998:CELF_RS09075
uniprot id: F4GYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

590998:CELF RS02480
gene id: 590998:CELF_RS02480
uniprot id: F4H881
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

590998:CELF RS14045
gene id: 590998:CELF_RS14045
uniprot id: F4H7E6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

590998:CELF RS13125
gene id: 590998:CELF_RS13125
uniprot id: F4H5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

590998:CELF RS03340
gene id: 590998:CELF_RS03340
uniprot id: F4GYU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

590998:CELF RS16480
gene id: 590998:CELF_RS16480
uniprot id: F4H109
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS18300
gene id: 590998:CELF_RS18300
uniprot id: F4H3R2
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS13815
gene id: 590998:CELF_RS13815
uniprot id: F4H7A3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

590998:CELF RS18510
gene id: 590998:CELF_RS18510
uniprot id: F4H4H6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

590998:CELF RS16720
gene id: 590998:CELF_RS16720
uniprot id: F4H158
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

590998:CELF RS08145
gene id: 590998:CELF_RS08145
uniprot id: F4H7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

590998:CELF RS10745
gene id: 590998:CELF_RS10745
uniprot id: F4H107
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

590998:CELF RS03255
gene id: 590998:CELF_RS03255
uniprot id: F4GYS3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

590998:CELF RS00375
gene id: 590998:CELF_RS00375
uniprot id: F4H400
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS04955
gene id: 590998:CELF_RS04955
uniprot id: F4H1E9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

590998:CELF RS05420
gene id: 590998:CELF_RS05420
uniprot id: F4H2I5
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

590998:CELF RS02945
gene id: 590998:CELF_RS02945
uniprot id: F4GY63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

590998:CELF RS15750
gene id: 590998:CELF_RS15750
uniprot id: F4GZS0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

590998:CELF RS08150
gene id: 590998:CELF_RS08150
uniprot id: F4H7R8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

590998:CELF RS16685
gene id: 590998:CELF_RS16685
uniprot id: F4H150
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS17610
gene id: 590998:CELF_RS17610
uniprot id: F4H2H6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

590998:CELF RS14625
gene id: 590998:CELF_RS14625
uniprot id: F4H8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

590998:CELF RS18105
gene id: 590998:CELF_RS18105
uniprot id: F4H3M5
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS10490
gene id: 590998:CELF_RS10490
uniprot id: F4H0V6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

590998:CELF RS04485
gene id: 590998:CELF_RS04485
uniprot id: F4H0Q5
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS06490
gene id: 590998:CELF_RS06490
uniprot id: F4H476
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11980
gene id: 590998:CELF_RS11980
uniprot id: F4H3F5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS15395
gene id: 590998:CELF_RS15395
uniprot id: F4GZ51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

590998:CELF RS10695
gene id: 590998:CELF_RS10695
uniprot id: F4H0Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

590998:CELF RS02895
gene id: 590998:CELF_RS02895
uniprot id: F4GY53
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS08820
gene id: 590998:CELF_RS08820
uniprot id: F4H8J7
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

590998:CELF RS14815
gene id: 590998:CELF_RS14815
uniprot id: F4H8Q0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07575
gene id: 590998:CELF_RS07575
uniprot id: F4H6K7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

590998:CELF RS11150
gene id: 590998:CELF_RS11150
uniprot id: F4H239
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

590998:CELF RS09870
gene id: 590998:CELF_RS09870
uniprot id: F4GZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

590998:CELF RS18050
gene id: 590998:CELF_RS18050
uniprot id: F4H3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

590998:CELF RS07655
gene id: 590998:CELF_RS07655
uniprot id: F4H722
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS06310
gene id: 590998:CELF_RS06310
uniprot id: F4H440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

590998:CELF RS00035
gene id: 590998:CELF_RS00035
uniprot id: F4H3T5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

590998:CELF RS06525
gene id: 590998:CELF_RS06525
uniprot id: F4H4V5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

590998:CELF RS11165
gene id: 590998:CELF_RS11165
uniprot id: F4H242
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

590998:CELF RS05715
gene id: 590998:CELF_RS05715
uniprot id: F4H2P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS00685
gene id: 590998:CELF_RS00685
uniprot id: F4H4T4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS15470
gene id: 590998:CELF_RS15470
uniprot id: F4GZ66
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

590998:CELF RS15760
gene id: 590998:CELF_RS15760
uniprot id: F4GZS2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

590998:CELF RS11995
gene id: 590998:CELF_RS11995
uniprot id: F4H3F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS01190
gene id: 590998:CELF_RS01190
uniprot id: F4H673
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS17775
gene id: 590998:CELF_RS17775
uniprot id: F4H311
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

590998:CELF RS06715
gene id: 590998:CELF_RS06715
uniprot id: F4H4Z3
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

590998:CELF RS08090
gene id: 590998:CELF_RS08090
uniprot id: F4H7Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

590998:CELF RS18530
gene id: 590998:CELF_RS18530
uniprot id: F4H4I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

590998:CELF RS00130
gene id: 590998:CELF_RS00130
uniprot id: F4H3V3
names: Similarity
messages: Belongs to the UPF0749 family.

590998:CELF RS12470
gene id: 590998:CELF_RS12470
uniprot id: F4H4B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

590998:CELF RS07300
gene id: 590998:CELF_RS07300
uniprot id: F4H6F1
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

590998:CELF RS06900
gene id: 590998:CELF_RS06900
uniprot id: F4H5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS05165
gene id: 590998:CELF_RS05165
uniprot id: F4H1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

590998:CELF RS03700
gene id: 590998:CELF_RS03700
uniprot id: F4GZF9
names: Similarity
messages: Belongs to the universal stress protein A family.

590998:CELF RS08460
gene id: 590998:CELF_RS08460
uniprot id: F4H8C8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

590998:CELF RS02390
gene id: 590998:CELF_RS02390
uniprot id: F4H865
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

590998:CELF RS08520
gene id: 590998:CELF_RS08520
uniprot id: F4H8E0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS06725
gene id: 590998:CELF_RS06725
uniprot id: F4H4Z5
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

590998:CELF RS18320
gene id: 590998:CELF_RS18320
uniprot id: F4H3R6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

590998:CELF RS08840
gene id: 590998:CELF_RS08840
uniprot id: F4GY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS05120
gene id: 590998:CELF_RS05120
uniprot id: F4H1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

590998:CELF RS13910
gene id: 590998:CELF_RS13910
uniprot id: F4H7C2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

590998:CELF RS11305
gene id: 590998:CELF_RS11305
uniprot id: F4H268
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

590998:CELF RS04210
gene id: 590998:CELF_RS04210
uniprot id: F4H053
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

590998:CELF RS10150
gene id: 590998:CELF_RS10150
uniprot id: F4H092
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

590998:CELF RS04765
gene id: 590998:CELF_RS04765
uniprot id: F4H1B3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

590998:CELF RS11865
gene id: 590998:CELF_RS11865
uniprot id: F4H2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

590998:CELF RS15405
gene id: 590998:CELF_RS15405
uniprot id: F4GZ53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS16405
gene id: 590998:CELF_RS16405
uniprot id: F4H0J4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

590998:CELF RS01800
gene id: 590998:CELF_RS01800
uniprot id: F4H6Z9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS08650
gene id: 590998:CELF_RS08650
uniprot id: F4H8G6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

590998:CELF RS11680
gene id: 590998:CELF_RS11680
uniprot id: F4H2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS15150
gene id: 590998:CELF_RS15150
uniprot id: F4GYK6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

590998:CELF RS17155
gene id: 590998:CELF_RS17155
uniprot id: F4H1U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS18995
gene id: 590998:CELF_RS18995
uniprot id: F4H5E4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

590998:CELF RS15600
gene id: 590998:CELF_RS15600
uniprot id: F4GZ92
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

590998:CELF RS05975
gene id: 590998:CELF_RS05975
uniprot id: F4H3A1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

590998:CELF RS03610
gene id: 590998:CELF_RS03610
uniprot id: F4GZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

590998:CELF RS05955
gene id: 590998:CELF_RS05955
uniprot id: F4H397
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

590998:CELF RS12245
gene id: 590998:CELF_RS12245
uniprot id: F4H3K8
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05100
gene id: 590998:CELF_RS05100
uniprot id: F4H1X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

590998:CELF RS10315
gene id: 590998:CELF_RS10315
uniprot id: F4H0C5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS09065
gene id: 590998:CELF_RS09065
uniprot id: F4GYD5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

590998:CELF RS05070
gene id: 590998:CELF_RS05070
uniprot id: F4H1X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

590998:CELF RS13140
gene id: 590998:CELF_RS13140
uniprot id: F4H5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

590998:CELF RS18185
gene id: 590998:CELF_RS18185
uniprot id: F4H3P0
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

590998:CELF RS06665
gene id: 590998:CELF_RS06665
uniprot id: F4H4Y3
names: Similarity
messages: Belongs to the HSP15 family.

590998:CELF RS04950
gene id: 590998:CELF_RS04950
uniprot id: F4H1E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

590998:CELF RS16075
gene id: 590998:CELF_RS16075
uniprot id: F4GZY2
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

590998:CELF RS10930
gene id: 590998:CELF_RS10930
uniprot id: F4H1J2
names: Similarity
messages: Belongs to the universal stress protein A family.

590998:CELF RS04665
gene id: 590998:CELF_RS04665
uniprot id: F4H193
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

590998:CELF RS09465
gene id: 590998:CELF_RS09465
uniprot id: F4GZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

590998:CELF RS07670
gene id: 590998:CELF_RS07670
uniprot id: F4H725
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

590998:CELF RS07570
gene id: 590998:CELF_RS07570
uniprot id: F4H6K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

590998:CELF RS10485
gene id: 590998:CELF_RS10485
uniprot id: F4H0V5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

590998:CELF RS05280
gene id: 590998:CELF_RS05280
uniprot id: F4H215
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS13320
gene id: 590998:CELF_RS13320
uniprot id: F4H635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

590998:CELF RS18255
gene id: 590998:CELF_RS18255
uniprot id: F4H3Q3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

590998:CELF RS09235
gene id: 590998:CELF_RS09235
uniprot id: F4GYW7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

590998:CELF RS08400
gene id: 590998:CELF_RS08400
uniprot id: F4H7W8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

590998:CELF RS04940
gene id: 590998:CELF_RS04940
uniprot id: F4H1E7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS10225
gene id: 590998:CELF_RS10225
uniprot id: F4H0A7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

590998:CELF RS16115
gene id: 590998:CELF_RS16115
uniprot id: F4H0D7
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

590998:CELF RS00445
gene id: 590998:CELF_RS00445
uniprot id: F4H4N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

590998:CELF RS02635
gene id: 590998:CELF_RS02635
uniprot id: F4H8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS03535
gene id: 590998:CELF_RS03535
uniprot id: F4GZC7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

590998:CELF RS05175
gene id: 590998:CELF_RS05175
uniprot id: F4H1Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

590998:CELF RS06345
gene id: 590998:CELF_RS06345
uniprot id: F4H447
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

590998:CELF RS10035
gene id: 590998:CELF_RS10035
uniprot id: F4H069
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

590998:CELF RS14110
gene id: 590998:CELF_RS14110
uniprot id: F4H7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

590998:CELF RS15965
gene id: 590998:CELF_RS15965
uniprot id: F4GZW3
names: Similarity
messages: Belongs to the SurE nucleotidase family.

590998:CELF RS07540
gene id: 590998:CELF_RS07540
uniprot id: F4H6K0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

590998:CELF RS00680
gene id: 590998:CELF_RS00680
uniprot id: F4H4T3
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS07965
gene id: 590998:CELF_RS07965
uniprot id: F4H783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

590998:CELF RS07975
gene id: 590998:CELF_RS07975
uniprot id: F4H785
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS08710
gene id: 590998:CELF_RS08710
uniprot id: F4H8H8
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS00100
gene id: 590998:CELF_RS00100
uniprot id: F4H3U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

590998:CELF RS13595
gene id: 590998:CELF_RS13595
uniprot id: F4H6R0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS15465
gene id: 590998:CELF_RS15465
uniprot id: F4GZ65
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

590998:CELF RS03890
gene id: 590998:CELF_RS03890
uniprot id: F4GZZ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS01905
gene id: 590998:CELF_RS01905
uniprot id: F4H7H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

590998:CELF RS16985
gene id: 590998:CELF_RS16985
uniprot id: F4H1Q9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS10040
gene id: 590998:CELF_RS10040
uniprot id: F4H070
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

590998:CELF RS16575
gene id: 590998:CELF_RS16575
uniprot id: F4H128
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS07040
gene id: 590998:CELF_RS07040
uniprot id: F4H5T4
names: Similarity
messages: Belongs to the peptidase M1 family.

590998:CELF RS14710
gene id: 590998:CELF_RS14710
uniprot id: F4H8N1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

590998:CELF RS10055
gene id: 590998:CELF_RS10055
uniprot id: F4H073
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

590998:CELF RS18695
gene id: 590998:CELF_RS18695
uniprot id: F4H4L2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

590998:CELF RS16060
gene id: 590998:CELF_RS16060
uniprot id: F4GZX9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

590998:CELF RS14255
gene id: 590998:CELF_RS14255
uniprot id: F4H7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

590998:CELF RS10725
gene id: 590998:CELF_RS10725
uniprot id: F4H103
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

590998:CELF RS17895
gene id: 590998:CELF_RS17895
uniprot id: F4H334
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11670
gene id: 590998:CELF_RS11670
uniprot id: F4H2T8
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

590998:CELF RS13300
gene id: 590998:CELF_RS13300
uniprot id: F4H631
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS01285
gene id: 590998:CELF_RS01285
uniprot id: F4H692
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

590998:CELF RS05825
gene id: 590998:CELF_RS05825
uniprot id: F4H371
names: Similarity
messages: Belongs to the peptidase M24B family.

590998:CELF RS07030
gene id: 590998:CELF_RS07030
uniprot id: F4H5T2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

590998:CELF RS07610
gene id: 590998:CELF_RS07610
uniprot id: F4H6L4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

590998:CELF RS17795
gene id: 590998:CELF_RS17795
uniprot id: F4H315
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

590998:CELF RS05610
gene id: 590998:CELF_RS05610
uniprot id: F4H2M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

590998:CELF RS14595
gene id: 590998:CELF_RS14595
uniprot id: F4H8K8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

590998:CELF RS09160
gene id: 590998:CELF_RS09160
uniprot id: F4GYF4
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

590998:CELF RS04825
gene id: 590998:CELF_RS04825
uniprot id: F4H1C7
names: Similarity
messages: Belongs to the peptidase S8 family.

590998:CELF RS08630
gene id: 590998:CELF_RS08630
uniprot id: F4H8G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS07600
gene id: 590998:CELF_RS07600
uniprot id: F4H6L2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

590998:CELF RS05015
gene id: 590998:CELF_RS05015
uniprot id: F4H1W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

590998:CELF RS08605
gene id: 590998:CELF_RS08605
uniprot id: F4H8F7
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS00165
gene id: 590998:CELF_RS00165
uniprot id: F4H3W0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07765
gene id: 590998:CELF_RS07765
uniprot id: F4H743
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

590998:CELF RS06315
gene id: 590998:CELF_RS06315
uniprot id: F4H441
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

590998:CELF RS17790
gene id: 590998:CELF_RS17790
uniprot id: F4H314
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS17680
gene id: 590998:CELF_RS17680
uniprot id: F4H2Z2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

590998:CELF RS00940
gene id: 590998:CELF_RS00940
uniprot id: F4H5L1
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

590998:CELF RS11840
gene id: 590998:CELF_RS11840
uniprot id: F4H2X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

590998:CELF RS14275
gene id: 590998:CELF_RS14275
uniprot id: F4H7Z0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

590998:CELF RS05030
gene id: 590998:CELF_RS05030
uniprot id: F4H1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

590998:CELF RS11780
gene id: 590998:CELF_RS11780
uniprot id: F4H2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

590998:CELF RS09835
gene id: 590998:CELF_RS09835
uniprot id: F4GZN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

590998:CELF RS07135
gene id: 590998:CELF_RS07135
uniprot id: F4H5V3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

590998:CELF RS19310
gene id: 590998:CELF_RS19310
uniprot id: F4H6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

590998:CELF RS09955
gene id: 590998:CELF_RS09955
uniprot id: F4GZQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS18640
gene id: 590998:CELF_RS18640
uniprot id: F4H4K2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

590998:CELF RS00095
gene id: 590998:CELF_RS00095
uniprot id: F4H3U6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

590998:CELF RS10900
gene id: 590998:CELF_RS10900
uniprot id: F4H1I6
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

590998:CELF RS10010
gene id: 590998:CELF_RS10010
uniprot id: F4H064
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

590998:CELF RS07890
gene id: 590998:CELF_RS07890
uniprot id: F4H768
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

590998:CELF RS15975
gene id: 590998:CELF_RS15975
uniprot id: F4GZW5
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05135
gene id: 590998:CELF_RS05135
uniprot id: F4H1Y6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

590998:CELF RS02005
gene id: 590998:CELF_RS02005
uniprot id: F4H7J1
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS12545
gene id: 590998:CELF_RS12545
uniprot id: F4H4D4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

590998:CELF RS07470
gene id: 590998:CELF_RS07470
uniprot id: F4H6I6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

590998:CELF RS09440
gene id: 590998:CELF_RS09440
uniprot id: F4GZ07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

590998:CELF RS18705
gene id: 590998:CELF_RS18705
uniprot id: F4H4L3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS19065
gene id: 590998:CELF_RS19065
uniprot id: F4H5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

590998:CELF RS09965
gene id: 590998:CELF_RS09965
uniprot id: F4GZQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS12385
gene id: 590998:CELF_RS12385
uniprot id: F4H4A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS14955
gene id: 590998:CELF_RS14955
uniprot id: F4GYG9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07100
gene id: 590998:CELF_RS07100
uniprot id: F4H5U6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

590998:CELF RS18890
gene id: 590998:CELF_RS18890
uniprot id: F4H5C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

590998:CELF RS08495
gene id: 590998:CELF_RS08495
uniprot id: F4H8D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS18335
gene id: 590998:CELF_RS18335
uniprot id: F4H3R8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS06175
gene id: 590998:CELF_RS06175
uniprot id: F4H413
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

590998:CELF RS14370
gene id: 590998:CELF_RS14370
uniprot id: F4H809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

590998:CELF RS11655
gene id: 590998:CELF_RS11655
uniprot id: F4H2T5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

590998:CELF RS08780
gene id: 590998:CELF_RS08780
uniprot id: F4H8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

590998:CELF RS01835
gene id: 590998:CELF_RS01835
uniprot id: F4H706
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS15650
gene id: 590998:CELF_RS15650
uniprot id: F4GZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

590998:CELF RS12100
gene id: 590998:CELF_RS12100
uniprot id: F4H3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

590998:CELF RS01950
gene id: 590998:CELF_RS01950
uniprot id: F4H7I0
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS10305
gene id: 590998:CELF_RS10305
uniprot id: F4H0C3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

590998:CELF RS14565
gene id: 590998:CELF_RS14565
uniprot id: F4H8K2
names: Similarity
messages: Belongs to the LOG family.

590998:CELF RS18260
gene id: 590998:CELF_RS18260
uniprot id: F4H3Q4
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

590998:CELF RS07555
gene id: 590998:CELF_RS07555
uniprot id: F4H6K3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

590998:CELF RS11060
gene id: 590998:CELF_RS11060
uniprot id: F4H1L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

590998:CELF RS18830
gene id: 590998:CELF_RS18830
uniprot id: F4H5A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

590998:CELF RS11845
gene id: 590998:CELF_RS11845
uniprot id: F4H2X3
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09355
gene id: 590998:CELF_RS09355
uniprot id: F4GYZ0
names: Similarity
messages: Belongs to the peptidase C15 family.

590998:CELF RS00780
gene id: 590998:CELF_RS00780
uniprot id: F4H5H9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

590998:CELF RS18315
gene id: 590998:CELF_RS18315
uniprot id: F4H3R5
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

590998:CELF RS00640
gene id: 590998:CELF_RS00640
uniprot id: F4H4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS14120
gene id: 590998:CELF_RS14120
uniprot id: F4H7G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

590998:CELF RS06700
gene id: 590998:CELF_RS06700
uniprot id: F4H4Z0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS20945
gene id: 590998:CELF_RS20945
uniprot id: F4H8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

590998:CELF RS06755
gene id: 590998:CELF_RS06755
uniprot id: F4H501
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS17650
gene id: 590998:CELF_RS17650
uniprot id: F4H2Y6
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS02915
gene id: 590998:CELF_RS02915
uniprot id: F4GY57
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

590998:CELF RS07020
gene id: 590998:CELF_RS07020
uniprot id: F4H5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

590998:CELF RS17305
gene id: 590998:CELF_RS17305
uniprot id: F4H2C4
names: Similarity
messages: Belongs to the peptidase S51 family.

590998:CELF RS09910
gene id: 590998:CELF_RS09910
uniprot id: F4GZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

590998:CELF RS09690
gene id: 590998:CELF_RS09690
uniprot id: F4GZK2
names: Similarity
messages: Belongs to the Dps family.

590998:CELF RS12225
gene id: 590998:CELF_RS12225
uniprot id: F4H3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

590998:CELF RS09915
gene id: 590998:CELF_RS09915
uniprot id: F4GZP8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

590998:CELF RS14685
gene id: 590998:CELF_RS14685
uniprot id: F4H8M6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

590998:CELF RS07565
gene id: 590998:CELF_RS07565
uniprot id: F4H6K5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

590998:CELF RS05390
gene id: 590998:CELF_RS05390
uniprot id: F4H2I0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

590998:CELF RS00115
gene id: 590998:CELF_RS00115
uniprot id: F4H3V0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

590998:CELF RS10155
gene id: 590998:CELF_RS10155
uniprot id: F4H093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

590998:CELF RS04750
gene id: 590998:CELF_RS04750
uniprot id: F4H1B0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS14175
gene id: 590998:CELF_RS14175
uniprot id: F4H7X2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

590998:CELF RS19490
gene id: 590998:CELF_RS19490
uniprot id: F4GYG2
names: Similarity
messages: Belongs to the universal stress protein A family.

590998:CELF RS08285
gene id: 590998:CELF_RS08285
uniprot id: F4H7U5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

590998:CELF RS15540
gene id: 590998:CELF_RS15540
uniprot id: F4GZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

590998:CELF RS10925
gene id: 590998:CELF_RS10925
uniprot id: F4H1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

590998:CELF RS14375
gene id: 590998:CELF_RS14375
uniprot id: F4H810
names: Similarity
messages: Belongs to the EfeM/EfeO family.

590998:CELF RS00030
gene id: 590998:CELF_RS00030
uniprot id: F4H3T4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

590998:CELF RS11280
gene id: 590998:CELF_RS11280
uniprot id: F4H263
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

590998:CELF RS03915
gene id: 590998:CELF_RS03915
uniprot id: F4H001
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

590998:CELF RS05250
gene id: 590998:CELF_RS05250
uniprot id: F4H209
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

590998:CELF RS19235
gene id: 590998:CELF_RS19235
uniprot id: F4H662
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

590998:CELF RS08525
gene id: 590998:CELF_RS08525
uniprot id: F4H8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS14645
gene id: 590998:CELF_RS14645
uniprot id: F4H8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

590998:CELF RS14550
gene id: 590998:CELF_RS14550
uniprot id: F4H8J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

590998:CELF RS07055
gene id: 590998:CELF_RS07055
uniprot id: F4H5T7
names: Similarity
messages: Belongs to the peptidase M13 family.

590998:CELF RS10905
gene id: 590998:CELF_RS10905
uniprot id: F4H1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

590998:CELF RS06255
gene id: 590998:CELF_RS06255
uniprot id: F4H429
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

590998:CELF RS12530
gene id: 590998:CELF_RS12530
uniprot id: F4H4D1
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS10775
gene id: 590998:CELF_RS10775
uniprot id: F4H1G1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

590998:CELF RS07735
gene id: 590998:CELF_RS07735
uniprot id: P14090
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
messages: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.

590998:CELF RS09410
gene id: 590998:CELF_RS09410
uniprot id: F4GZ01
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

590998:CELF RS10240
gene id: 590998:CELF_RS10240
uniprot id: F4H0B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

590998:CELF RS17740
gene id: 590998:CELF_RS17740
uniprot id: F4H304
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

590998:CELF RS08985
gene id: 590998:CELF_RS08985
uniprot id: F4GYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

590998:CELF RS08925
gene id: 590998:CELF_RS08925
uniprot id: F4GYB0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

590998:CELF RS10235
gene id: 590998:CELF_RS10235
uniprot id: F4H0A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

590998:CELF RS13305
gene id: 590998:CELF_RS13305
uniprot id: F4H632
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09310
gene id: 590998:CELF_RS09310
uniprot id: F4GYY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

590998:CELF RS05980
gene id: 590998:CELF_RS05980
uniprot id: F4H3A3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

590998:CELF RS04355
gene id: 590998:CELF_RS04355
uniprot id: F4H0N0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS08335
gene id: 590998:CELF_RS08335
uniprot id: F4H7V5
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

590998:CELF RS20930
gene id: 590998:CELF_RS20930
uniprot id: F4GZK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

590998:CELF RS02355
gene id: 590998:CELF_RS02355
uniprot id: F4H858
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS18910
gene id: 590998:CELF_RS18910
uniprot id: F4H5C5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS07645
gene id: 590998:CELF_RS07645
uniprot id: F4H720
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

590998:CELF RS02765
gene id: 590998:CELF_RS02765
uniprot id: F4GY27
names: Similarity
messages: Belongs to the peptidase S13 family.

590998:CELF RS13870
gene id: 590998:CELF_RS13870
uniprot id: F4H7B4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

590998:CELF RS05065
gene id: 590998:CELF_RS05065
uniprot id: F4H1X2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

590998:CELF RS15295
gene id: 590998:CELF_RS15295
uniprot id: F4GYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

590998:CELF RS12600
gene id: 590998:CELF_RS12600
uniprot id: F4H4E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

590998:CELF RS14420
gene id: 590998:CELF_RS14420
uniprot id: F4H819
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

590998:CELF RS05245
gene id: 590998:CELF_RS05245
uniprot id: F4H208
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

590998:CELF RS12345
gene id: 590998:CELF_RS12345
uniprot id: F4H497
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

590998:CELF RS07105
gene id: 590998:CELF_RS07105
uniprot id: F4H5U7
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS06160
gene id: 590998:CELF_RS06160
uniprot id: F4H409
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

590998:CELF RS08185
gene id: 590998:CELF_RS08185
uniprot id: F4H7S5
names: Subcellular Location Annotation
messages: Cytoplasm

590998:CELF RS04460
gene id: 590998:CELF_RS04460
uniprot id: F4H0Q0
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

590998:CELF RS05770
gene id: 590998:CELF_RS05770
uniprot id: F4H360
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS13860
gene id: 590998:CELF_RS13860
uniprot id: F4H7B2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS07720
gene id: 590998:CELF_RS07720
uniprot id: F4H734
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07560
gene id: 590998:CELF_RS07560
uniprot id: F4H6K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

590998:CELF RS14480
gene id: 590998:CELF_RS14480
uniprot id: F4H831
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

590998:CELF RS14380
gene id: 590998:CELF_RS14380
uniprot id: F4H811
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

590998:CELF RS12740
gene id: 590998:CELF_RS12740
uniprot id: F4H542
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS06895
gene id: 590998:CELF_RS06895
uniprot id: F4H5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS07900
gene id: 590998:CELF_RS07900
uniprot id: F4H770
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

590998:CELF RS09130
gene id: 590998:CELF_RS09130
uniprot id: F4GYE8
names: Similarity
messages: Belongs to the TrpC family.

590998:CELF RS11050
gene id: 590998:CELF_RS11050
uniprot id: F4H1L6
names: Similarity
messages: Belongs to the ComB family.

590998:CELF RS02780
gene id: 590998:CELF_RS02780
uniprot id: F4GY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

590998:CELF RS14540
gene id: 590998:CELF_RS14540
uniprot id: F4H843
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

590998:CELF RS17780
gene id: 590998:CELF_RS17780
uniprot id: F4H312
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

590998:CELF RS14800
gene id: 590998:CELF_RS14800
uniprot id: F4H8P7
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS17365
gene id: 590998:CELF_RS17365
uniprot id: F4H2D5
names: Subcellular Location Annotation
messages: Cytoplasm

590998:CELF RS18155
gene id: 590998:CELF_RS18155
uniprot id: F4H3N4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

590998:CELF RS09035
gene id: 590998:CELF_RS09035
uniprot id: F4GYD1
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

590998:CELF RS03145
gene id: 590998:CELF_RS03145
uniprot id: F4GYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

590998:CELF RS01260
gene id: 590998:CELF_RS01260
uniprot id: F4H687
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

590998:CELF RS09820
gene id: 590998:CELF_RS09820
uniprot id: F4GZM9
names: Similarity
messages: Belongs to the UPF0303 family.

590998:CELF RS01915
gene id: 590998:CELF_RS01915
uniprot id: F4H7H3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

590998:CELF RS02530
gene id: 590998:CELF_RS02530
uniprot id: F4H891
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS00015
gene id: 590998:CELF_RS00015
uniprot id: F4H359
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

590998:CELF RS09905
gene id: 590998:CELF_RS09905
uniprot id: F4GZP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

590998:CELF RS21250
gene id: 590998:CELF_RS21250
uniprot id: F4H0H6
names: Similarity
messages: Belongs to the GARS family.

590998:CELF RS07745
gene id: 590998:CELF_RS07745
uniprot id: F4H739
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

590998:CELF RS07495
gene id: 590998:CELF_RS07495
uniprot id: F4H6J1
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS13120
gene id: 590998:CELF_RS13120
uniprot id: F4H5Z5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

590998:CELF RS08955
gene id: 590998:CELF_RS08955
uniprot id: F4GYB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

590998:CELF RS01165
gene id: 590998:CELF_RS01165
uniprot id: F4H669
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS15960
gene id: 590998:CELF_RS15960
uniprot id: F4GZW2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

590998:CELF RS05020
gene id: 590998:CELF_RS05020
uniprot id: F4H1W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

590998:CELF RS03605
gene id: 590998:CELF_RS03605
uniprot id: F4GZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

590998:CELF RS11310
gene id: 590998:CELF_RS11310
uniprot id: F4H269
names: Similarity
messages: Belongs to the glutamine synthetase family.

590998:CELF RS07865
gene id: 590998:CELF_RS07865
uniprot id: F4H763
names: Similarity
messages: Belongs to the FPG family.

590998:CELF RS03505
gene id: 590998:CELF_RS03505
uniprot id: F4GZC1
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS12400
gene id: 590998:CELF_RS12400
uniprot id: F4H4A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

590998:CELF RS10685
gene id: 590998:CELF_RS10685
uniprot id: F4H0Z5
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

590998:CELF RS02800
gene id: 590998:CELF_RS02800
uniprot id: F4GY34
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

590998:CELF RS07290
gene id: 590998:CELF_RS07290
uniprot id: F4H6E9
names: Similarity
messages: Belongs to the UPF0145 family.

590998:CELF RS12070
gene id: 590998:CELF_RS12070
uniprot id: F4H3H3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

590998:CELF RS11170
gene id: 590998:CELF_RS11170
uniprot id: F4H243
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

590998:CELF RS00530
gene id: 590998:CELF_RS00530
uniprot id: F4H4Q4
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS16595
gene id: 590998:CELF_RS16595
uniprot id: F4H132
names: Similarity
messages: Belongs to the UxaA family.

590998:CELF RS08815
gene id: 590998:CELF_RS08815
uniprot id: F4H8J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

590998:CELF RS18195
gene id: 590998:CELF_RS18195
uniprot id: F4H3P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS16300
gene id: 590998:CELF_RS16300
uniprot id: F4H0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

590998:CELF RS10475
gene id: 590998:CELF_RS10475
uniprot id: F4H0V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

590998:CELF RS03480
gene id: 590998:CELF_RS03480
uniprot id: F4GZB6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

590998:CELF RS12260
gene id: 590998:CELF_RS12260
uniprot id: F4H480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

590998:CELF RS02520
gene id: 590998:CELF_RS02520
uniprot id: F4H889
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

590998:CELF RS10810
gene id: 590998:CELF_RS10810
uniprot id: F4H1G8
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

590998:CELF RS04615
gene id: 590998:CELF_RS04615
uniprot id: F4H0T0
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS11330
gene id: 590998:CELF_RS11330
uniprot id: F4H274
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

590998:CELF RS18635
gene id: 590998:CELF_RS18635
uniprot id: F4H4K1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

590998:CELF RS04715
gene id: 590998:CELF_RS04715
uniprot id: F4H1A3
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

590998:CELF RS02850
gene id: 590998:CELF_RS02850
uniprot id: F4GY44
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

590998:CELF RS05235
gene id: 590998:CELF_RS05235
uniprot id: F4H206
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

590998:CELF RS03325
gene id: 590998:CELF_RS03325
uniprot id: F4GYT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

590998:CELF RS04920
gene id: 590998:CELF_RS04920
uniprot id: F4H1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

590998:CELF RS05050
gene id: 590998:CELF_RS05050
uniprot id: F4H1W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

590998:CELF RS15155
gene id: 590998:CELF_RS15155
uniprot id: F4GYK7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

590998:CELF RS11450
gene id: 590998:CELF_RS11450
uniprot id: F4H297
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

590998:CELF RS13620
gene id: 590998:CELF_RS13620
uniprot id: F4H6R5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

590998:CELF RS05555
gene id: 590998:CELF_RS05555
uniprot id: F4H2L2
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS06225
gene id: 590998:CELF_RS06225
uniprot id: F4H423
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

590998:CELF RS13615
gene id: 590998:CELF_RS13615
uniprot id: F4H6R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

590998:CELF RS03435
gene id: 590998:CELF_RS03435
uniprot id: F4GYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

590998:CELF RS11875
gene id: 590998:CELF_RS11875
uniprot id: F4H2X9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

590998:CELF RS11740
gene id: 590998:CELF_RS11740
uniprot id: F4H2V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS14395
gene id: 590998:CELF_RS14395
uniprot id: F4H814
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

590998:CELF RS09070
gene id: 590998:CELF_RS09070
uniprot id: F4GYD6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

590998:CELF RS11625
gene id: 590998:CELF_RS11625
uniprot id: F4H2S9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

590998:CELF RS16515
gene id: 590998:CELF_RS16515
uniprot id: F4H116
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

590998:CELF RS13015
gene id: 590998:CELF_RS13015
uniprot id: F4H598
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

590998:CELF RS05985
gene id: 590998:CELF_RS05985
uniprot id: F4H3A4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

590998:CELF RS05240
gene id: 590998:CELF_RS05240
uniprot id: F4H207
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

590998:CELF RS09655
gene id: 590998:CELF_RS09655
uniprot id: F4GZJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

590998:CELF RS11115
gene id: 590998:CELF_RS11115
uniprot id: F4H1M9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

590998:CELF RS10175
gene id: 590998:CELF_RS10175
uniprot id: F4H097
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

590998:CELF RS06780
gene id: 590998:CELF_RS06780
uniprot id: F4H506
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS05720
gene id: 590998:CELF_RS05720
uniprot id: F4H2P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

590998:CELF RS00010
gene id: 590998:CELF_RS00010
uniprot id: F4H358
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

590998:CELF RS00400
gene id: 590998:CELF_RS00400
uniprot id: F4H4M7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS14070
gene id: 590998:CELF_RS14070
uniprot id: F4H7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS08390
gene id: 590998:CELF_RS08390
uniprot id: F4H7W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

590998:CELF RS03420
gene id: 590998:CELF_RS03420
uniprot id: F4GYV6
names: Similarity
messages: Belongs to the MotB family.

590998:CELF RS18800
gene id: 590998:CELF_RS18800
uniprot id: F4H5A3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

590998:CELF RS11870
gene id: 590998:CELF_RS11870
uniprot id: F4H2X8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

590998:CELF RS15350
gene id: 590998:CELF_RS15350
uniprot id: F4GZ42
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

590998:CELF RS04520
gene id: 590998:CELF_RS04520
uniprot id: F4H0R2
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

590998:CELF RS01405
gene id: 590998:CELF_RS01405
uniprot id: F4H6B7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

590998:CELF RS09350
gene id: 590998:CELF_RS09350
uniprot id: F4GYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

590998:CELF RS15765
gene id: 590998:CELF_RS15765
uniprot id: F4GZS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

590998:CELF RS00765
gene id: 590998:CELF_RS00765
uniprot id: F4H4U9
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS09340
gene id: 590998:CELF_RS09340
uniprot id: F4GYY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS17925
gene id: 590998:CELF_RS17925
uniprot id: F4H340
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07625
gene id: 590998:CELF_RS07625
uniprot id: F4H6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

590998:CELF RS08160
gene id: 590998:CELF_RS08160
uniprot id: F4H7S0
names: Similarity
messages: Belongs to the YggT family.

590998:CELF RS12875
gene id: 590998:CELF_RS12875
uniprot id: F4H569
names: Similarity
messages: Belongs to the PrpD family.

590998:CELF RS11085
gene id: 590998:CELF_RS11085
uniprot id: F4H1M3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

590998:CELF RS03010
gene id: 590998:CELF_RS03010
uniprot id: F4GY77
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS02985
gene id: 590998:CELF_RS02985
uniprot id: F4GY72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

590998:CELF RS04705
gene id: 590998:CELF_RS04705
uniprot id: F4H1A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

590998:CELF RS13540
gene id: 590998:CELF_RS13540
uniprot id: F4H6P9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS12230
gene id: 590998:CELF_RS12230
uniprot id: F4H3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

590998:CELF RS13685
gene id: 590998:CELF_RS13685
uniprot id: F4H6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS03665
gene id: 590998:CELF_RS03665
uniprot id: F4GZF2
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS11775
gene id: 590998:CELF_RS11775
uniprot id: F4H2V9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

590998:CELF RS02270
gene id: 590998:CELF_RS02270
uniprot id: F4H7P1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

590998:CELF RS01015
gene id: 590998:CELF_RS01015
uniprot id: F4H5M6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

590998:CELF RS01240
gene id: 590998:CELF_RS01240
uniprot id: F4H683
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

590998:CELF RS02340
gene id: 590998:CELF_RS02340
uniprot id: F4H855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

590998:CELF RS13820
gene id: 590998:CELF_RS13820
uniprot id: F4H7A4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

590998:CELF RS04865
gene id: 590998:CELF_RS04865
uniprot id: F4H1D5
names: Similarity
messages: Belongs to the UPF0234 family.

590998:CELF RS14790
gene id: 590998:CELF_RS14790
uniprot id: F4H8P5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

590998:CELF RS11940
gene id: 590998:CELF_RS11940
uniprot id: F4H3E6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

590998:CELF RS14415
gene id: 590998:CELF_RS14415
uniprot id: F4H818
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

590998:CELF RS17355
gene id: 590998:CELF_RS17355
uniprot id: F4H2D3
names: Subcellular Location Annotation
messages: Cytoplasm

590998:CELF RS13950
gene id: 590998:CELF_RS13950
uniprot id: F4H7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS05095
gene id: 590998:CELF_RS05095
uniprot id: F4H1X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

590998:CELF RS12820
gene id: 590998:CELF_RS12820
uniprot id: F4H558
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

590998:CELF RS17370
gene id: 590998:CELF_RS17370
uniprot id: F4H2D6
names: Similarity
messages: Belongs to the UPF0225 family.

590998:CELF RS08175
gene id: 590998:CELF_RS08175
uniprot id: F4H7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

590998:CELF RS18200
gene id: 590998:CELF_RS18200
uniprot id: F4H3P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS19095
gene id: 590998:CELF_RS19095
uniprot id: F4H5G3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

590998:CELF RS15020
gene id: 590998:CELF_RS15020
uniprot id: F4GYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS08775
gene id: 590998:CELF_RS08775
uniprot id: F4H8J0
names: Similarity
messages: Belongs to the DapA family.

590998:CELF RS17825
gene id: 590998:CELF_RS17825
uniprot id: F4H321
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

590998:CELF RS15280
gene id: 590998:CELF_RS15280
uniprot id: F4GYM7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

590998:CELF RS04650
gene id: 590998:CELF_RS04650
uniprot id: F4H190
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS11640
gene id: 590998:CELF_RS11640
uniprot id: F4H2T2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

590998:CELF RS05285
gene id: 590998:CELF_RS05285
uniprot id: F4H216
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

590998:CELF RS08600
gene id: 590998:CELF_RS08600
uniprot id: F4H8F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

590998:CELF RS12735
gene id: 590998:CELF_RS12735
uniprot id: F4H541
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

590998:CELF RS05275
gene id: 590998:CELF_RS05275
uniprot id: F4H214
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

590998:CELF RS05005
gene id: 590998:CELF_RS05005
uniprot id: F4H1W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

590998:CELF RS14510
gene id: 590998:CELF_RS14510
uniprot id: F4H837
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS03415
gene id: 590998:CELF_RS03415
uniprot id: F4GYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

590998:CELF RS14885
gene id: 590998:CELF_RS14885
uniprot id: F4H8R4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

590998:CELF RS15590
gene id: 590998:CELF_RS15590
uniprot id: F4GZ90
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

590998:CELF RS13960
gene id: 590998:CELF_RS13960
uniprot id: F4H7D2
names: Similarity
messages: Belongs to the glycosyl hydrolase.

590998:CELF RS18070
gene id: 590998:CELF_RS18070
uniprot id: F4H3L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

590998:CELF RS09615
gene id: 590998:CELF_RS09615
uniprot id: F4GZI7
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS03365
gene id: 590998:CELF_RS03365
uniprot id: F4GYU5
names: Subcellular Location Annotation
messages: Cytoplasm

590998:CELF RS01630
gene id: 590998:CELF_RS01630
uniprot id: F4H6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

590998:CELF RS17705
gene id: 590998:CELF_RS17705
uniprot id: F4H2Z7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

590998:CELF RS04960
gene id: 590998:CELF_RS04960
uniprot id: F4H1F0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

590998:CELF RS11755
gene id: 590998:CELF_RS11755
uniprot id: F4H2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS20230
gene id: 590998:CELF_RS20230
uniprot id: F4H124
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

590998:CELF RS16525
gene id: 590998:CELF_RS16525
uniprot id: F4H118
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS02595
gene id: 590998:CELF_RS02595
uniprot id: F4H8A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

590998:CELF RS11160
gene id: 590998:CELF_RS11160
uniprot id: F4H241
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

590998:CELF RS03715
gene id: 590998:CELF_RS03715
uniprot id: F4GZG2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS04795
gene id: 590998:CELF_RS04795
uniprot id: F4H1C0
names: Similarity
messages: Belongs to the WXG100 family.

590998:CELF RS07805
gene id: 590998:CELF_RS07805
uniprot id: F4H751
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

590998:CELF RS05475
gene id: 590998:CELF_RS05475
uniprot id: F4H2J6
names: Similarity
messages: Belongs to the XFP family.

590998:CELF RS19135
gene id: 590998:CELF_RS19135
uniprot id: F4H5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

590998:CELF RS15920
gene id: 590998:CELF_RS15920
uniprot id: F4GZV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

590998:CELF RS04220
gene id: 590998:CELF_RS04220
uniprot id: F4H055
names: Similarity
messages: Belongs to the GSP E family.

590998:CELF RS15040
gene id: 590998:CELF_RS15040
uniprot id: F4GYI5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

590998:CELF RS13610
gene id: 590998:CELF_RS13610
uniprot id: F4H6R3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

590998:CELF RS19690
gene id: 590998:CELF_RS19690
uniprot id: F4H0D2
names: Similarity
messages: Belongs to the peptidase S1B family.

590998:CELF RS04085
gene id: 590998:CELF_RS04085
uniprot id: F4H033
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

590998:CELF RS08310
gene id: 590998:CELF_RS08310
uniprot id: F4H7V0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

590998:CELF RS16340
gene id: 590998:CELF_RS16340
uniprot id: F4H0I1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

590998:CELF RS19205
gene id: 590998:CELF_RS19205
uniprot id: F4H657
names: Similarity
messages: Belongs to the ParB family.

590998:CELF RS08370
gene id: 590998:CELF_RS08370
uniprot id: F4H7W2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

590998:CELF RS01160
gene id: 590998:CELF_RS01160
uniprot id: F4H668
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

590998:CELF RS03370
gene id: 590998:CELF_RS03370
uniprot id: F4GYU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

590998:CELF RS03390
gene id: 590998:CELF_RS03390
uniprot id: F4GYV0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

590998:CELF RS07685
gene id: 590998:CELF_RS07685
uniprot id: F4H728
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

590998:CELF RS13810
gene id: 590998:CELF_RS13810
uniprot id: F4H7A2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

590998:CELF RS13440
gene id: 590998:CELF_RS13440
uniprot id: F4H6M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

590998:CELF RS01870
gene id: 590998:CELF_RS01870
uniprot id: F4H713
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

590998:CELF RS13930
gene id: 590998:CELF_RS13930
uniprot id: F4H7C6
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

590998:CELF RS04710
gene id: 590998:CELF_RS04710
uniprot id: F4H1A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

590998:CELF RS01705
gene id: 590998:CELF_RS01705
uniprot id: F4H6Y0
names: Similarity
messages: Belongs to the YciI family.

590998:CELF RS07715
gene id: 590998:CELF_RS07715
uniprot id: F4H733
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

590998:CELF RS08115
gene id: 590998:CELF_RS08115
uniprot id: F4H7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

590998:CELF RS14235
gene id: 590998:CELF_RS14235
uniprot id: F4H7Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

590998:CELF RS08380
gene id: 590998:CELF_RS08380
uniprot id: F4H7W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

590998:CELF RS15000
gene id: 590998:CELF_RS15000
uniprot id: F4GYH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

590998:CELF RS17405
gene id: 590998:CELF_RS17405
uniprot id: F4H2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

590998:CELF RS08110
gene id: 590998:CELF_RS08110
uniprot id: F4H7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

590998:CELF RS10275
gene id: 590998:CELF_RS10275
uniprot id: F4H0B7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

590998:CELF RS08265
gene id: 590998:CELF_RS08265
uniprot id: F4H7U1
names: Similarity
messages: Belongs to the catalase family.

590998:CELF RS15055
gene id: 590998:CELF_RS15055
uniprot id: F4GYI8
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS06445
gene id: 590998:CELF_RS06445
uniprot id: F4H467
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

590998:CELF RS14660
gene id: 590998:CELF_RS14660
uniprot id: F4H8M1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

590998:CELF RS05150
gene id: 590998:CELF_RS05150
uniprot id: F4H1Y9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

590998:CELF RS05575
gene id: 590998:CELF_RS05575
uniprot id: F4H2L6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

590998:CELF RS19570
gene id: 590998:CELF_RS19570
uniprot id: F4H531
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

590998:CELF RS06405
gene id: 590998:CELF_RS06405
uniprot id: F4H459
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

590998:CELF RS01270
gene id: 590998:CELF_RS01270
uniprot id: F4H689
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

590998:CELF RS15995
gene id: 590998:CELF_RS15995
uniprot id: F4GZW9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

590998:CELF RS14125
gene id: 590998:CELF_RS14125
uniprot id: F4H7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

590998:CELF RS06275
gene id: 590998:CELF_RS06275
uniprot id: F4H433
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS07905
gene id: 590998:CELF_RS07905
uniprot id: F4H771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

590998:CELF RS13705
gene id: 590998:CELF_RS13705
uniprot id: F4H6T2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

590998:CELF RS17860
gene id: 590998:CELF_RS17860
uniprot id: F4H328
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

590998:CELF RS16195
gene id: 590998:CELF_RS16195
uniprot id: F4H0F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

590998:CELF RS02275
gene id: 590998:CELF_RS02275
uniprot id: F4H7P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

590998:CELF RS07995
gene id: 590998:CELF_RS07995
uniprot id: F4H789
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

590998:CELF RS05650
gene id: 590998:CELF_RS05650
uniprot id: F4H2N1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

590998:CELF RS10465
gene id: 590998:CELF_RS10465
uniprot id: F4H0V1
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

590998:CELF RS05525
gene id: 590998:CELF_RS05525
uniprot id: F4H2K6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

590998:CELF RS13565
gene id: 590998:CELF_RS13565
uniprot id: F4H6Q5
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07635
gene id: 590998:CELF_RS07635
uniprot id: F4H718
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

590998:CELF RS10800
gene id: 590998:CELF_RS10800
uniprot id: F4H1G6
names: Similarity
messages: Belongs to the arginase family.

590998:CELF RS17180
gene id: 590998:CELF_RS17180
uniprot id: F4H1U9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

590998:CELF RS03745
gene id: 590998:CELF_RS03745
uniprot id: F4GZG8
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS17945
gene id: 590998:CELF_RS17945
uniprot id: F4H344
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

590998:CELF RS13560
gene id: 590998:CELF_RS13560
uniprot id: F4H6Q4
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS07730
gene id: 590998:CELF_RS07730
uniprot id: F4H736
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

590998:CELF RS05155
gene id: 590998:CELF_RS05155
uniprot id: F4H1Z0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

590998:CELF RS12180
gene id: 590998:CELF_RS12180
uniprot id: F4H3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

590998:CELF RS15505
gene id: 590998:CELF_RS15505
uniprot id: F4GZ73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

590998:CELF RS08620
gene id: 590998:CELF_RS08620
uniprot id: F4H8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

590998:CELF RS03575
gene id: 590998:CELF_RS03575
uniprot id: F4GZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

590998:CELF RS16650
gene id: 590998:CELF_RS16650
uniprot id: F4H143
names: Similarity
messages: Belongs to the AHA1 family.

590998:CELF RS09765
gene id: 590998:CELF_RS09765
uniprot id: F4GZL7
names: Similarity
messages: Belongs to the UPF0749 family.

590998:CELF RS08610
gene id: 590998:CELF_RS08610
uniprot id: F4H8F8
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS09100
gene id: 590998:CELF_RS09100
uniprot id: F4GYE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

590998:CELF RS04500
gene id: 590998:CELF_RS04500
uniprot id: F4H0Q7
names: Similarity
messages: Belongs to the histone deacetylase family.

590998:CELF RS04550
gene id: 590998:CELF_RS04550
uniprot id: F4H0R7
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

590998:CELF RS09285
gene id: 590998:CELF_RS09285
uniprot id: F4GYX6
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS05270
gene id: 590998:CELF_RS05270
uniprot id: F4H213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

590998:CELF RS19290
gene id: 590998:CELF_RS19290
uniprot id: F4H5N9
names: Subcellular Location Annotation
messages: Membrane

590998:CELF RS03985
gene id: 590998:CELF_RS03985
uniprot id: F4H015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS05805
gene id: 590998:CELF_RS05805
uniprot id: F4H367
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

590998:CELF RS00635
gene id: 590998:CELF_RS00635
uniprot id: F4H4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

590998:CELF RS14130
gene id: 590998:CELF_RS14130
uniprot id: F4H7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

590998:CELF RS03825
gene id: 590998:CELF_RS03825
uniprot id: F4GZI3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

590998:CELF RS05080
gene id: 590998:CELF_RS05080
uniprot id: F4H1X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

590998:CELF RS10970
gene id: 590998:CELF_RS10970
uniprot id: F4H1K0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

590998:CELF RS11025
gene id: 590998:CELF_RS11025
uniprot id: F4H1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane