583358:TMATH RS04510
gene id: 583358:TMATH_RS04510
uniprot id: D7AN70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

583358:TMATH RS05630
gene id: 583358:TMATH_RS05630
uniprot id: D7ANT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

583358:TMATH RS09720
gene id: 583358:TMATH_RS09720
uniprot id: D7AS55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

583358:TMATH RS02570
gene id: 583358:TMATH_RS02570
uniprot id: D7ASQ1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

583358:TMATH RS03070
gene id: 583358:TMATH_RS03070
uniprot id: D7ATC4
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

583358:TMATH RS01450
gene id: 583358:TMATH_RS01450
uniprot id: D7ARS1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

583358:TMATH RS06750
gene id: 583358:TMATH_RS06750
uniprot id: D7APF6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

583358:TMATH RS04675
gene id: 583358:TMATH_RS04675
uniprot id: D7ANA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

583358:TMATH RS04835
gene id: 583358:TMATH_RS04835
uniprot id: D7AND5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

583358:TMATH RS10100
gene id: 583358:TMATH_RS10100
uniprot id: D7ASC9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

583358:TMATH RS10070
gene id: 583358:TMATH_RS10070
uniprot id: D7ASC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS06130
gene id: 583358:TMATH_RS06130
uniprot id: D7AP31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

583358:TMATH RS07405
gene id: 583358:TMATH_RS07405
uniprot id: D7APS4
names: Similarity
messages: Belongs to the transpeptidase family.

583358:TMATH RS05470
gene id: 583358:TMATH_RS05470
uniprot id: D7ANQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

583358:TMATH RS03810
gene id: 583358:TMATH_RS03810
uniprot id: D7ATZ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

583358:TMATH RS08105
gene id: 583358:TMATH_RS08105
uniprot id: D7AQ79
names: Similarity
messages: Belongs to the ABC transporter superfamily.

583358:TMATH RS01685
gene id: 583358:TMATH_RS01685
uniprot id: D7ARW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

583358:TMATH RS05530
gene id: 583358:TMATH_RS05530
uniprot id: D7ANR2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS05370
gene id: 583358:TMATH_RS05370
uniprot id: D7ANN0
names: Similarity
messages: Belongs to the RecJ family.

583358:TMATH RS00850
gene id: 583358:TMATH_RS00850
uniprot id: D7AR38
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS02205
gene id: 583358:TMATH_RS02205
uniprot id: D7ASI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

583358:TMATH RS01500
gene id: 583358:TMATH_RS01500
uniprot id: D7ART1
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS05375
gene id: 583358:TMATH_RS05375
uniprot id: D7ANN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS02975
gene id: 583358:TMATH_RS02975
uniprot id: D7ATA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

583358:TMATH RS07120
gene id: 583358:TMATH_RS07120
uniprot id: D7APL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

583358:TMATH RS02985
gene id: 583358:TMATH_RS02985
uniprot id: D7ATA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

583358:TMATH RS02260
gene id: 583358:TMATH_RS02260
uniprot id: D7ASJ7
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

583358:TMATH RS04090
gene id: 583358:TMATH_RS04090
uniprot id: D7AMY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS07710
gene id: 583358:TMATH_RS07710
uniprot id: D7AQ05
names: Subcellular Location Annotation
messages: Cytoplasm

583358:TMATH RS04405
gene id: 583358:TMATH_RS04405
uniprot id: D7AN50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

583358:TMATH RS09125
gene id: 583358:TMATH_RS09125
uniprot id: D7ARI1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

583358:TMATH RS07450
gene id: 583358:TMATH_RS07450
uniprot id: D7APT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

583358:TMATH RS09100
gene id: 583358:TMATH_RS09100
uniprot id: D7ARH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

583358:TMATH RS00975
gene id: 583358:TMATH_RS00975
uniprot id: D7AR63
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

583358:TMATH RS03465
gene id: 583358:TMATH_RS03465
uniprot id: D7ATS8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

583358:TMATH RS09650
gene id: 583358:TMATH_RS09650
uniprot id: D7ARR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

583358:TMATH RS04165
gene id: 583358:TMATH_RS04165
uniprot id: D7AN04
names: Similarity
messages: Belongs to the peptidase S49 family.

583358:TMATH RS08460
gene id: 583358:TMATH_RS08460
uniprot id: D7AQS3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

583358:TMATH RS08365
gene id: 583358:TMATH_RS08365
uniprot id: D7AQQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

583358:TMATH RS06105
gene id: 583358:TMATH_RS06105
uniprot id: D7AP26
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

583358:TMATH RS08570
gene id: 583358:TMATH_RS08570
uniprot id: D7AQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

583358:TMATH RS03450
gene id: 583358:TMATH_RS03450
uniprot id: D7ATS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

583358:TMATH RS06685
gene id: 583358:TMATH_RS06685
uniprot id: D7APE3
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

583358:TMATH RS00980
gene id: 583358:TMATH_RS00980
uniprot id: D7AR64
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS09070
gene id: 583358:TMATH_RS09070
uniprot id: D7ARH0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS11050
gene id: 583358:TMATH_RS11050
uniprot id: D7ATK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS03130
gene id: 583358:TMATH_RS03130
uniprot id: D7ATD6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

583358:TMATH RS04265
gene id: 583358:TMATH_RS04265
uniprot id: D7AN23
names: Similarity
messages: Belongs to the NadC/ModD family.

583358:TMATH RS06305
gene id: 583358:TMATH_RS06305
uniprot id: D7AP66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

583358:TMATH RS03120
gene id: 583358:TMATH_RS03120
uniprot id: D7ATD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

583358:TMATH RS03100
gene id: 583358:TMATH_RS03100
uniprot id: D7ATD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

583358:TMATH RS10470
gene id: 583358:TMATH_RS10470
uniprot id: D7ASW7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

583358:TMATH RS09605
gene id: 583358:TMATH_RS09605
uniprot id: D7ARQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

583358:TMATH RS04395
gene id: 583358:TMATH_RS04395
uniprot id: D7AN48
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

583358:TMATH RS06465
gene id: 583358:TMATH_RS06465
uniprot id: D7AP98
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

583358:TMATH RS03630
gene id: 583358:TMATH_RS03630
uniprot id: D7ATW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

583358:TMATH RS06210
gene id: 583358:TMATH_RS06210
uniprot id: D7AP47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

583358:TMATH RS08965
gene id: 583358:TMATH_RS08965
uniprot id: D7AR19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

583358:TMATH RS04250
gene id: 583358:TMATH_RS04250
uniprot id: D7AN21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

583358:TMATH RS05355
gene id: 583358:TMATH_RS05355
uniprot id: D7ANM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

583358:TMATH RS00510
gene id: 583358:TMATH_RS00510
uniprot id: D7AQK1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

583358:TMATH RS01910
gene id: 583358:TMATH_RS01910
uniprot id: D7AS12
names: Similarity
messages: Belongs to the CapA family.

583358:TMATH RS01230
gene id: 583358:TMATH_RS01230
uniprot id: D7ARB6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

583358:TMATH RS09860
gene id: 583358:TMATH_RS09860
uniprot id: D7AS82
names: Similarity
messages: Belongs to the CtsR family.

583358:TMATH RS09695
gene id: 583358:TMATH_RS09695
uniprot id: D7AS50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

583358:TMATH RS11145
gene id: 583358:TMATH_RS11145
uniprot id: D7ATM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

583358:TMATH RS06790
gene id: 583358:TMATH_RS06790
uniprot id: D7APG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583358:TMATH RS07110
gene id: 583358:TMATH_RS07110
uniprot id: D7APL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS08800
gene id: 583358:TMATH_RS08800
uniprot id: D7AQY8
names: Similarity
messages: Belongs to the CdaR family.

583358:TMATH RS05610
gene id: 583358:TMATH_RS05610
uniprot id: D7ANS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

583358:TMATH RS07875
gene id: 583358:TMATH_RS07875
uniprot id: D7AQ32
names: Similarity
messages: Belongs to the sigma-54 factor family.

583358:TMATH RS04365
gene id: 583358:TMATH_RS04365
uniprot id: D7AN42
names: Similarity
messages: Belongs to the UPF0758 family.

583358:TMATH RS06015
gene id: 583358:TMATH_RS06015
uniprot id: D7AP08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

583358:TMATH RS10030
gene id: 583358:TMATH_RS10030
uniprot id: D7ASB5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

583358:TMATH RS09710
gene id: 583358:TMATH_RS09710
uniprot id: D7AS53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

583358:TMATH RS08425
gene id: 583358:TMATH_RS08425
uniprot id: D7AQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

583358:TMATH RS08165
gene id: 583358:TMATH_RS08165
uniprot id: D7AQ91
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

583358:TMATH RS02015
gene id: 583358:TMATH_RS02015
uniprot id: D7AS33
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

583358:TMATH RS02765
gene id: 583358:TMATH_RS02765
uniprot id: D7AT63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

583358:TMATH RS09830
gene id: 583358:TMATH_RS09830
uniprot id: D7AS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS08195
gene id: 583358:TMATH_RS08195
uniprot id: D7AQ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS09165
gene id: 583358:TMATH_RS09165
uniprot id: D7ARI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09890
gene id: 583358:TMATH_RS09890
uniprot id: D7AS88
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

583358:TMATH RS00630
gene id: 583358:TMATH_RS00630
uniprot id: D7AQM0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

583358:TMATH RS06440
gene id: 583358:TMATH_RS06440
uniprot id: D7AP93
names: Similarity
messages: Belongs to the DprA/Smf family.

583358:TMATH RS09930
gene id: 583358:TMATH_RS09930
uniprot id: D7AS95
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS01700
gene id: 583358:TMATH_RS01700
uniprot id: D7ARX1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

583358:TMATH RS00190
gene id: 583358:TMATH_RS00190
uniprot id: D7AQD9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

583358:TMATH RS05285
gene id: 583358:TMATH_RS05285
uniprot id: D7ANL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

583358:TMATH RS02595
gene id: 583358:TMATH_RS02595
uniprot id: D7ASQ6
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS03975
gene id: 583358:TMATH_RS03975
uniprot id: D7AU24
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

583358:TMATH RS08215
gene id: 583358:TMATH_RS08215
uniprot id: D7AQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

583358:TMATH RS07615
gene id: 583358:TMATH_RS07615
uniprot id: D7APW6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583358:TMATH RS01125
gene id: 583358:TMATH_RS01125
uniprot id: D7AR94
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

583358:TMATH RS07630
gene id: 583358:TMATH_RS07630
uniprot id: D7APW9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

583358:TMATH RS00575
gene id: 583358:TMATH_RS00575
uniprot id: D7AQK9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

583358:TMATH RS02295
gene id: 583358:TMATH_RS02295
uniprot id: D7ASK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS06335
gene id: 583358:TMATH_RS06335
uniprot id: D7AP72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

583358:TMATH RS02810
gene id: 583358:TMATH_RS02810
uniprot id: D7AT72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

583358:TMATH RS10875
gene id: 583358:TMATH_RS10875
uniprot id: D7AT50
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

583358:TMATH RS04465
gene id: 583358:TMATH_RS04465
uniprot id: D7AN62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

583358:TMATH RS03580
gene id: 583358:TMATH_RS03580
uniprot id: D7ATV1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

583358:TMATH RS07900
gene id: 583358:TMATH_RS07900
uniprot id: D7AQ37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

583358:TMATH RS08070
gene id: 583358:TMATH_RS08070
uniprot id: D7AQ72
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

583358:TMATH RS08265
gene id: 583358:TMATH_RS08265
uniprot id: D7AQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06380
gene id: 583358:TMATH_RS06380
uniprot id: D7AP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS05050
gene id: 583358:TMATH_RS05050
uniprot id: D7ANG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

583358:TMATH RS04765
gene id: 583358:TMATH_RS04765
uniprot id: D7ANC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

583358:TMATH RS06655
gene id: 583358:TMATH_RS06655
uniprot id: D7APD7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

583358:TMATH RS10180
gene id: 583358:TMATH_RS10180
uniprot id: D7ASE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

583358:TMATH RS06195
gene id: 583358:TMATH_RS06195
uniprot id: D7AP44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

583358:TMATH RS10495
gene id: 583358:TMATH_RS10495
uniprot id: D7ASX2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

583358:TMATH RS02080
gene id: 583358:TMATH_RS02080
uniprot id: D7AS43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583358:TMATH RS00905
gene id: 583358:TMATH_RS00905
uniprot id: D7AR49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583358:TMATH RS02200
gene id: 583358:TMATH_RS02200
uniprot id: D7ASI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

583358:TMATH RS00115
gene id: 583358:TMATH_RS00115
uniprot id: D7AQ00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

583358:TMATH RS10970
gene id: 583358:TMATH_RS10970
uniprot id: D7ATI5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

583358:TMATH RS01150
gene id: 583358:TMATH_RS01150
uniprot id: D7AR99
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS09155
gene id: 583358:TMATH_RS09155
uniprot id: D7ARI7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

583358:TMATH RS10895
gene id: 583358:TMATH_RS10895
uniprot id: D7AT54
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

583358:TMATH RS02575
gene id: 583358:TMATH_RS02575
uniprot id: D7ASQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

583358:TMATH RS06480
gene id: 583358:TMATH_RS06480
uniprot id: D7APA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

583358:TMATH RS03395
gene id: 583358:TMATH_RS03395
uniprot id: D7ATH7
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

583358:TMATH RS09755
gene id: 583358:TMATH_RS09755
uniprot id: D7AS61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

583358:TMATH RS08770
gene id: 583358:TMATH_RS08770
uniprot id: D7AQY2
names: Similarity
messages: Belongs to the ComB family.

583358:TMATH RS00885
gene id: 583358:TMATH_RS00885
uniprot id: D7AR45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583358:TMATH RS02610
gene id: 583358:TMATH_RS02610
uniprot id: D7ASQ9
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

583358:TMATH RS03140
gene id: 583358:TMATH_RS03140
uniprot id: D7ATD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

583358:TMATH RS06800
gene id: 583358:TMATH_RS06800
uniprot id: D7APG6
names: Similarity
messages: Belongs to the RemA family.

583358:TMATH RS01095
gene id: 583358:TMATH_RS01095
uniprot id: D7AR88
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS05005
gene id: 583358:TMATH_RS05005
uniprot id: D7ANF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

583358:TMATH RS01560
gene id: 583358:TMATH_RS01560
uniprot id: D7ARU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

583358:TMATH RS02835
gene id: 583358:TMATH_RS02835
uniprot id: D7AT76
names: Similarity
messages: Belongs to the asparagine synthetase family.

583358:TMATH RS10510
gene id: 583358:TMATH_RS10510
uniprot id: D7ASX5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

583358:TMATH RS09665
gene id: 583358:TMATH_RS09665
uniprot id: D7ARR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

583358:TMATH RS04825
gene id: 583358:TMATH_RS04825
uniprot id: D7AND3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS08990
gene id: 583358:TMATH_RS08990
uniprot id: D7AR24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

583358:TMATH RS07205
gene id: 583358:TMATH_RS07205
uniprot id: D7APN6
names: Similarity
messages: Belongs to the RutC family.

583358:TMATH RS08285
gene id: 583358:TMATH_RS08285
uniprot id: D7AQB7
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS05850
gene id: 583358:TMATH_RS05850
uniprot id: D7ANX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

583358:TMATH RS10660
gene id: 583358:TMATH_RS10660
uniprot id: D7AT04
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583358:TMATH RS00515
gene id: 583358:TMATH_RS00515
uniprot id: D7AQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

583358:TMATH RS08590
gene id: 583358:TMATH_RS08590
uniprot id: D7AQU9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

583358:TMATH RS03990
gene id: 583358:TMATH_RS03990
uniprot id: D7AU27
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

583358:TMATH RS12035
gene id: 583358:TMATH_RS12035
uniprot id: D7APS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

583358:TMATH RS06625
gene id: 583358:TMATH_RS06625
uniprot id: D7APD1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

583358:TMATH RS11010
gene id: 583358:TMATH_RS11010
uniprot id: D7ATJ3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

583358:TMATH RS10065
gene id: 583358:TMATH_RS10065
uniprot id: D7ASC2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583358:TMATH RS01725
gene id: 583358:TMATH_RS01725
uniprot id: D7ARX6
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS09210
gene id: 583358:TMATH_RS09210
uniprot id: D7ARJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

583358:TMATH RS02005
gene id: 583358:TMATH_RS02005
uniprot id: D7AS31
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

583358:TMATH RS01170
gene id: 583358:TMATH_RS01170
uniprot id: D7ARA3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583358:TMATH RS07240
gene id: 583358:TMATH_RS07240
uniprot id: D7APP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

583358:TMATH RS00590
gene id: 583358:TMATH_RS00590
uniprot id: D7AQL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

583358:TMATH RS03260
gene id: 583358:TMATH_RS03260
uniprot id: D7ATG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

583358:TMATH RS07440
gene id: 583358:TMATH_RS07440
uniprot id: D7APT1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

583358:TMATH RS06415
gene id: 583358:TMATH_RS06415
uniprot id: D7AP88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

583358:TMATH RS09900
gene id: 583358:TMATH_RS09900
uniprot id: D7AS90
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

583358:TMATH RS03155
gene id: 583358:TMATH_RS03155
uniprot id: D7ATE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

583358:TMATH RS09730
gene id: 583358:TMATH_RS09730
uniprot id: D7AS57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

583358:TMATH RS00665
gene id: 583358:TMATH_RS00665
uniprot id: D7AQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

583358:TMATH RS06915
gene id: 583358:TMATH_RS06915
uniprot id: D7API4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS06475
gene id: 583358:TMATH_RS06475
uniprot id: D7APA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

583358:TMATH RS06935
gene id: 583358:TMATH_RS06935
uniprot id: D7API8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

583358:TMATH RS02255
gene id: 583358:TMATH_RS02255
uniprot id: D7ASJ6
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

583358:TMATH RS09065
gene id: 583358:TMATH_RS09065
uniprot id: D7ARG9
names: Similarity
messages: Belongs to the peptidase M20A family.

583358:TMATH RS03840
gene id: 583358:TMATH_RS03840
uniprot id: D7ATZ8
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS07645
gene id: 583358:TMATH_RS07645
uniprot id: D7APX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

583358:TMATH RS08720
gene id: 583358:TMATH_RS08720
uniprot id: D7AQX2
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

583358:TMATH RS08820
gene id: 583358:TMATH_RS08820
uniprot id: D7AQZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

583358:TMATH RS05015
gene id: 583358:TMATH_RS05015
uniprot id: D7ANG0
names: Similarity
messages: Belongs to the peptidase C56 family.

583358:TMATH RS06785
gene id: 583358:TMATH_RS06785
uniprot id: D7APG3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS06205
gene id: 583358:TMATH_RS06205
uniprot id: D7AP46
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS07410
gene id: 583358:TMATH_RS07410
uniprot id: D7APS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

583358:TMATH RS00175
gene id: 583358:TMATH_RS00175
uniprot id: D7AQD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS01065
gene id: 583358:TMATH_RS01065
uniprot id: D7AR82
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

583358:TMATH RS09170
gene id: 583358:TMATH_RS09170
uniprot id: D7ARJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

583358:TMATH RS05680
gene id: 583358:TMATH_RS05680
uniprot id: D7ANU2
names: Similarity
messages: Belongs to the asp23 family.

583358:TMATH RS00830
gene id: 583358:TMATH_RS00830
uniprot id: D7AR34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

583358:TMATH RS06065
gene id: 583358:TMATH_RS06065
uniprot id: D7AP18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

583358:TMATH RS00705
gene id: 583358:TMATH_RS00705
uniprot id: D7AQN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583358:TMATH RS07330
gene id: 583358:TMATH_RS07330
uniprot id: D7APQ9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

583358:TMATH RS05975
gene id: 583358:TMATH_RS05975
uniprot id: D7AP01
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

583358:TMATH RS11395
gene id: 583358:TMATH_RS11395
uniprot id: D7ATR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

583358:TMATH RS00155
gene id: 583358:TMATH_RS00155
uniprot id: D7AQD2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09055
gene id: 583358:TMATH_RS09055
uniprot id: D7ARG7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583358:TMATH RS03345
gene id: 583358:TMATH_RS03345
uniprot id: D7ATG8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

583358:TMATH RS02455
gene id: 583358:TMATH_RS02455
uniprot id: D7ASN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

583358:TMATH RS01905
gene id: 583358:TMATH_RS01905
uniprot id: D7AS11
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

583358:TMATH RS03245
gene id: 583358:TMATH_RS03245
uniprot id: D7ATF8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

583358:TMATH RS01050
gene id: 583358:TMATH_RS01050
uniprot id: D7AR78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

583358:TMATH RS10320
gene id: 583358:TMATH_RS10320
uniprot id: D7AST7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

583358:TMATH RS07845
gene id: 583358:TMATH_RS07845
uniprot id: D7AQ26
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

583358:TMATH RS00045
gene id: 583358:TMATH_RS00045
uniprot id: D7APY8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

583358:TMATH RS01120
gene id: 583358:TMATH_RS01120
uniprot id: D7AR93
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583358:TMATH RS07285
gene id: 583358:TMATH_RS07285
uniprot id: D7APQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

583358:TMATH RS07090
gene id: 583358:TMATH_RS07090
uniprot id: D7APL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

583358:TMATH RS00720
gene id: 583358:TMATH_RS00720
uniprot id: D7AQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

583358:TMATH RS08615
gene id: 583358:TMATH_RS08615
uniprot id: D7AQV2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

583358:TMATH RS10590
gene id: 583358:TMATH_RS10590
uniprot id: D7ASZ0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

583358:TMATH RS01580
gene id: 583358:TMATH_RS01580
uniprot id: D7ARU7
names: Similarity
messages: Belongs to the Fur family.

583358:TMATH RS03425
gene id: 583358:TMATH_RS03425
uniprot id: D7ATS3
names: Similarity
messages: Belongs to the leucine-binding protein family.

583358:TMATH RS04290
gene id: 583358:TMATH_RS04290
uniprot id: D7AN27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS06615
gene id: 583358:TMATH_RS06615
uniprot id: D7APC9
names: Similarity
messages: Belongs to the fabD family.

583358:TMATH RS06310
gene id: 583358:TMATH_RS06310
uniprot id: D7AP67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

583358:TMATH RS08025
gene id: 583358:TMATH_RS08025
uniprot id: D7AQ63
names: Similarity
messages: Belongs to the HypE family.

583358:TMATH RS10335
gene id: 583358:TMATH_RS10335
uniprot id: D7ASU0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS08765
gene id: 583358:TMATH_RS08765
uniprot id: D7AQY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

583358:TMATH RS10890
gene id: 583358:TMATH_RS10890
uniprot id: D7AT53
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

583358:TMATH RS07370
gene id: 583358:TMATH_RS07370
uniprot id: D7APR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS02970
gene id: 583358:TMATH_RS02970
uniprot id: D7ATA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

583358:TMATH RS10120
gene id: 583358:TMATH_RS10120
uniprot id: D7ASD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

583358:TMATH RS10745
gene id: 583358:TMATH_RS10745
uniprot id: D7AT21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

583358:TMATH RS03005
gene id: 583358:TMATH_RS03005
uniprot id: D7ATB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

583358:TMATH RS00205
gene id: 583358:TMATH_RS00205
uniprot id: D7AQE2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

583358:TMATH RS10870
gene id: 583358:TMATH_RS10870
uniprot id: D7AT49
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

583358:TMATH RS04855
gene id: 583358:TMATH_RS04855
uniprot id: D7AND9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

583358:TMATH RS02865
gene id: 583358:TMATH_RS02865
uniprot id: D7AT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

583358:TMATH RS07480
gene id: 583358:TMATH_RS07480
uniprot id: D7APT9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

583358:TMATH RS02100
gene id: 583358:TMATH_RS02100
uniprot id: D7ASG7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

583358:TMATH RS11225
gene id: 583358:TMATH_RS11225
uniprot id: D7ATN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

583358:TMATH RS02625
gene id: 583358:TMATH_RS02625
uniprot id: D7ASR1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

583358:TMATH RS11215
gene id: 583358:TMATH_RS11215
uniprot id: D7ATN5
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

583358:TMATH RS04370
gene id: 583358:TMATH_RS04370
uniprot id: D7AN43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS06010
gene id: 583358:TMATH_RS06010
uniprot id: D7AP07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

583358:TMATH RS00215
gene id: 583358:TMATH_RS00215
uniprot id: D7AQE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS04715
gene id: 583358:TMATH_RS04715
uniprot id: D7ANB0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

583358:TMATH RS09635
gene id: 583358:TMATH_RS09635
uniprot id: D7ARR1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

583358:TMATH RS06640
gene id: 583358:TMATH_RS06640
uniprot id: D7APD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

583358:TMATH RS06630
gene id: 583358:TMATH_RS06630
uniprot id: D7APD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

583358:TMATH RS05800
gene id: 583358:TMATH_RS05800
uniprot id: D7ANW7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

583358:TMATH RS07100
gene id: 583358:TMATH_RS07100
uniprot id: D7APL5
names: Similarity
messages: Belongs to the TrpF family.

583358:TMATH RS06040
gene id: 583358:TMATH_RS06040
uniprot id: D7AP13
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583358:TMATH RS06675
gene id: 583358:TMATH_RS06675
uniprot id: D7APE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

583358:TMATH RS06295
gene id: 583358:TMATH_RS06295
uniprot id: D7AP64
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

583358:TMATH RS10110
gene id: 583358:TMATH_RS10110
uniprot id: D7ASD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

583358:TMATH RS08230
gene id: 583358:TMATH_RS08230
uniprot id: D7AQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

583358:TMATH RS03490
gene id: 583358:TMATH_RS03490
uniprot id: D7ATT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

583358:TMATH RS07830
gene id: 583358:TMATH_RS07830
uniprot id: D7AQ23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

583358:TMATH RS08375
gene id: 583358:TMATH_RS08375
uniprot id: D7AQQ5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

583358:TMATH RS05120
gene id: 583358:TMATH_RS05120
uniprot id: D7ANI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

583358:TMATH RS00150
gene id: 583358:TMATH_RS00150
uniprot id: D7AQD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

583358:TMATH RS06005
gene id: 583358:TMATH_RS06005
uniprot id: D7AP06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

583358:TMATH RS09615
gene id: 583358:TMATH_RS09615
uniprot id: D7ARQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

583358:TMATH RS08565
gene id: 583358:TMATH_RS08565
uniprot id: D7AQU4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

583358:TMATH RS08960
gene id: 583358:TMATH_RS08960
uniprot id: D7AR18
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

583358:TMATH RS05090
gene id: 583358:TMATH_RS05090
uniprot id: D7ANH5
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

583358:TMATH RS02815
gene id: 583358:TMATH_RS02815
uniprot id: D7AT73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

583358:TMATH RS10730
gene id: 583358:TMATH_RS10730
uniprot id: D7AT18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

583358:TMATH RS02215
gene id: 583358:TMATH_RS02215
uniprot id: D7ASJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

583358:TMATH RS00810
gene id: 583358:TMATH_RS00810
uniprot id: D7AR30
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

583358:TMATH RS02990
gene id: 583358:TMATH_RS02990
uniprot id: D7ATA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

583358:TMATH RS08040
gene id: 583358:TMATH_RS08040
uniprot id: D7AQ66
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

583358:TMATH RS02115
gene id: 583358:TMATH_RS02115
uniprot id: D7ASH0
names: Similarity
messages: Belongs to the CobH/CbiC family.

583358:TMATH RS06710
gene id: 583358:TMATH_RS06710
uniprot id: D7APE8
names: Similarity
messages: Belongs to the asp23 family.

583358:TMATH RS10600
gene id: 583358:TMATH_RS10600
uniprot id: D7ASZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS07305
gene id: 583358:TMATH_RS07305
uniprot id: D7APQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

583358:TMATH RS08150
gene id: 583358:TMATH_RS08150
uniprot id: D7AQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

583358:TMATH RS03150
gene id: 583358:TMATH_RS03150
uniprot id: D7ATE0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

583358:TMATH RS05965
gene id: 583358:TMATH_RS05965
uniprot id: D7ANZ9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

583358:TMATH RS02420
gene id: 583358:TMATH_RS02420
uniprot id: D7ASM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06540
gene id: 583358:TMATH_RS06540
uniprot id: D7APB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

583358:TMATH RS01880
gene id: 583358:TMATH_RS01880
uniprot id: D7AS06
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

583358:TMATH RS08970
gene id: 583358:TMATH_RS08970
uniprot id: D7AR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

583358:TMATH RS02525
gene id: 583358:TMATH_RS02525
uniprot id: D7ASP2
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS02685
gene id: 583358:TMATH_RS02685
uniprot id: D7ASS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06830
gene id: 583358:TMATH_RS06830
uniprot id: D7APH2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

583358:TMATH RS06225
gene id: 583358:TMATH_RS06225
uniprot id: D7AP50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

583358:TMATH RS02160
gene id: 583358:TMATH_RS02160
uniprot id: D7ASH9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

583358:TMATH RS01535
gene id: 583358:TMATH_RS01535
uniprot id: D7ART8
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS00130
gene id: 583358:TMATH_RS00130
uniprot id: D7AQ03
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

583358:TMATH RS05455
gene id: 583358:TMATH_RS05455
uniprot id: D7ANP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583358:TMATH RS00640
gene id: 583358:TMATH_RS00640
uniprot id: D7AQM2
names: Similarity
messages: Belongs to the class-I fumarase family.

583358:TMATH RS04175
gene id: 583358:TMATH_RS04175
uniprot id: D7AN06
names: Similarity
messages: Belongs to the HepT RNase toxin family.

583358:TMATH RS01455
gene id: 583358:TMATH_RS01455
uniprot id: D7ARS2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583358:TMATH RS01885
gene id: 583358:TMATH_RS01885
uniprot id: D7AS07
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

583358:TMATH RS01840
gene id: 583358:TMATH_RS01840
uniprot id: D7ARZ8
names: Similarity
messages: Belongs to the Tlp family.

583358:TMATH RS01915
gene id: 583358:TMATH_RS01915
uniprot id: D7AS13
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

583358:TMATH RS10500
gene id: 583358:TMATH_RS10500
uniprot id: D7ASX3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

583358:TMATH RS01225
gene id: 583358:TMATH_RS01225
uniprot id: D7ARB5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

583358:TMATH RS01940
gene id: 583358:TMATH_RS01940
uniprot id: D7AS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS04080
gene id: 583358:TMATH_RS04080
uniprot id: D7AU45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

583358:TMATH RS04130
gene id: 583358:TMATH_RS04130
uniprot id: D7AMZ6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583358:TMATH RS08380
gene id: 583358:TMATH_RS08380
uniprot id: D7AQQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

583358:TMATH RS08465
gene id: 583358:TMATH_RS08465
uniprot id: D7AQS4
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

583358:TMATH RS01180
gene id: 583358:TMATH_RS01180
uniprot id: D7ARA5
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS02855
gene id: 583358:TMATH_RS02855
uniprot id: D7AT80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

583358:TMATH RS03185
gene id: 583358:TMATH_RS03185
uniprot id: D7ATE7
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS07400
gene id: 583358:TMATH_RS07400
uniprot id: D7APS3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09765
gene id: 583358:TMATH_RS09765
uniprot id: D7AS63
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

583358:TMATH RS09800
gene id: 583358:TMATH_RS09800
uniprot id: D7AS70
names: Similarity
messages: Belongs to the ycf81 family.

583358:TMATH RS01490
gene id: 583358:TMATH_RS01490
uniprot id: D7ARS9
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS03025
gene id: 583358:TMATH_RS03025
uniprot id: D7ATB4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS11220
gene id: 583358:TMATH_RS11220
uniprot id: D7ATN6
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS05765
gene id: 583358:TMATH_RS05765
uniprot id: D7ANV9
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS11185
gene id: 583358:TMATH_RS11185
uniprot id: D7ATM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

583358:TMATH RS05715
gene id: 583358:TMATH_RS05715
uniprot id: D7ANU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

583358:TMATH RS07350
gene id: 583358:TMATH_RS07350
uniprot id: D7APR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

583358:TMATH RS01765
gene id: 583358:TMATH_RS01765
uniprot id: D7ARY3
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

583358:TMATH RS07140
gene id: 583358:TMATH_RS07140
uniprot id: D7APM3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

583358:TMATH RS06470
gene id: 583358:TMATH_RS06470
uniprot id: D7AP99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

583358:TMATH RS07935
gene id: 583358:TMATH_RS07935
uniprot id: D7AQ44
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

583358:TMATH RS04035
gene id: 583358:TMATH_RS04035
uniprot id: D7AU36
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

583358:TMATH RS04850
gene id: 583358:TMATH_RS04850
uniprot id: D7AND8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

583358:TMATH RS07980
gene id: 583358:TMATH_RS07980
uniprot id: D7AQ53
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

583358:TMATH RS02175
gene id: 583358:TMATH_RS02175
uniprot id: D7ASI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

583358:TMATH RS11370
gene id: 583358:TMATH_RS11370
uniprot id: D7ATR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

583358:TMATH RS03375
gene id: 583358:TMATH_RS03375
uniprot id: D7ATH3
names: Similarity
messages: Belongs to the ThiD family.

583358:TMATH RS06585
gene id: 583358:TMATH_RS06585
uniprot id: D7APC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS02580
gene id: 583358:TMATH_RS02580
uniprot id: D7ASQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

583358:TMATH RS11280
gene id: 583358:TMATH_RS11280
uniprot id: D7ATP6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

583358:TMATH RS06135
gene id: 583358:TMATH_RS06135
uniprot id: D7AP32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

583358:TMATH RS02460
gene id: 583358:TMATH_RS02460
uniprot id: D7ASN1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

583358:TMATH RS04505
gene id: 583358:TMATH_RS04505
uniprot id: D7AN69
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

583358:TMATH RS06140
gene id: 583358:TMATH_RS06140
uniprot id: D7AP33
names: Similarity
messages: Belongs to the ribF family.

583358:TMATH RS10765
gene id: 583358:TMATH_RS10765
uniprot id: D7AT25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

583358:TMATH RS01680
gene id: 583358:TMATH_RS01680
uniprot id: D7ARW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

583358:TMATH RS00900
gene id: 583358:TMATH_RS00900
uniprot id: D7AR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583358:TMATH RS06000
gene id: 583358:TMATH_RS06000
uniprot id: D7AP05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583358:TMATH RS01005
gene id: 583358:TMATH_RS01005
uniprot id: D7AR69
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

583358:TMATH RS02070
gene id: 583358:TMATH_RS02070
uniprot id: D7AS41
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

583358:TMATH RS05695
gene id: 583358:TMATH_RS05695
uniprot id: D7ANU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

583358:TMATH RS04240
gene id: 583358:TMATH_RS04240
uniprot id: D7AN19
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583358:TMATH RS08075
gene id: 583358:TMATH_RS08075
uniprot id: D7AQ73
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS00785
gene id: 583358:TMATH_RS00785
uniprot id: D7AR25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

583358:TMATH RS07375
gene id: 583358:TMATH_RS07375
uniprot id: D7APR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS04040
gene id: 583358:TMATH_RS04040
uniprot id: D7AU37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S8 family.
messages: Monomer.
messages: Serine protease with a broad substrate specificity.

583358:TMATH RS09545
gene id: 583358:TMATH_RS09545
uniprot id: D7ARP3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

583358:TMATH RS11335
gene id: 583358:TMATH_RS11335
uniprot id: D7ATQ7
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

583358:TMATH RS05335
gene id: 583358:TMATH_RS05335
uniprot id: D7ANM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

583358:TMATH RS00220
gene id: 583358:TMATH_RS00220
uniprot id: D7AQE6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS11070
gene id: 583358:TMATH_RS11070
uniprot id: D7ATK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09840
gene id: 583358:TMATH_RS09840
uniprot id: D7AS78
names: Similarity
messages: Belongs to the DtxR/MntR family.

583358:TMATH RS09795
gene id: 583358:TMATH_RS09795
uniprot id: D7AS69
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

583358:TMATH RS01040
gene id: 583358:TMATH_RS01040
uniprot id: D7AR76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

583358:TMATH RS06500
gene id: 583358:TMATH_RS06500
uniprot id: D7APA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

583358:TMATH RS03550
gene id: 583358:TMATH_RS03550
uniprot id: D7ATU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583358:TMATH RS01145
gene id: 583358:TMATH_RS01145
uniprot id: D7AR98
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS10575
gene id: 583358:TMATH_RS10575
uniprot id: D7ASY7
names: Similarity
messages: Belongs to the peptidase C40 family.

583358:TMATH RS00920
gene id: 583358:TMATH_RS00920
uniprot id: D7AR53
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS00890
gene id: 583358:TMATH_RS00890
uniprot id: D7AR46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583358:TMATH RS03500
gene id: 583358:TMATH_RS03500
uniprot id: D7ATT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

583358:TMATH RS11065
gene id: 583358:TMATH_RS11065
uniprot id: D7ATK5
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS04770
gene id: 583358:TMATH_RS04770
uniprot id: D7ANC2
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS02465
gene id: 583358:TMATH_RS02465
uniprot id: D7ASN2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

583358:TMATH RS02210
gene id: 583358:TMATH_RS02210
uniprot id: D7ASI9
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS03700
gene id: 583358:TMATH_RS03700
uniprot id: D7ATX4
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

583358:TMATH RS09660
gene id: 583358:TMATH_RS09660
uniprot id: D7ARR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

583358:TMATH RS05620
gene id: 583358:TMATH_RS05620
uniprot id: D7ANT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

583358:TMATH RS10000
gene id: 583358:TMATH_RS10000
uniprot id: D7ASA9
names: Similarity
messages: Belongs to the SfsA family.

583358:TMATH RS03135
gene id: 583358:TMATH_RS03135
uniprot id: D7ATD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

583358:TMATH RS06215
gene id: 583358:TMATH_RS06215
uniprot id: D7AP48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

583358:TMATH RS04535
gene id: 583358:TMATH_RS04535
uniprot id: D7AN75
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

583358:TMATH RS11300
gene id: 583358:TMATH_RS11300
uniprot id: D7ATQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

583358:TMATH RS06395
gene id: 583358:TMATH_RS06395
uniprot id: D7AP84
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

583358:TMATH RS00790
gene id: 583358:TMATH_RS00790
uniprot id: D7AR26
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS00250
gene id: 583358:TMATH_RS00250
uniprot id: D7AQE9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

583358:TMATH RS04020
gene id: 583358:TMATH_RS04020
uniprot id: D7AU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS09685
gene id: 583358:TMATH_RS09685
uniprot id: D7AS48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

583358:TMATH RS00035
gene id: 583358:TMATH_RS00035
uniprot id: D7APY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

583358:TMATH RS07860
gene id: 583358:TMATH_RS07860
uniprot id: D7AQ29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS08955
gene id: 583358:TMATH_RS08955
uniprot id: D7AR17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09760
gene id: 583358:TMATH_RS09760
uniprot id: D7AS62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS09825
gene id: 583358:TMATH_RS09825
uniprot id: D7AS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS02375
gene id: 583358:TMATH_RS02375
uniprot id: D7ASL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS10155
gene id: 583358:TMATH_RS10155
uniprot id: D7ASE0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

583358:TMATH RS02655
gene id: 583358:TMATH_RS02655
uniprot id: D7ASR7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

583358:TMATH RS08925
gene id: 583358:TMATH_RS08925
uniprot id: D7AR12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

583358:TMATH RS08640
gene id: 583358:TMATH_RS08640
uniprot id: D7AQV7
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

583358:TMATH RS11405
gene id: 583358:TMATH_RS11405
uniprot id: D7ATS1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

583358:TMATH RS05540
gene id: 583358:TMATH_RS05540
uniprot id: D7ANR4
names: Similarity
messages: Belongs to the GSP E family.

583358:TMATH RS07345
gene id: 583358:TMATH_RS07345
uniprot id: D7APR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

583358:TMATH RS09120
gene id: 583358:TMATH_RS09120
uniprot id: D7ARI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS05870
gene id: 583358:TMATH_RS05870
uniprot id: D7ANY0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

583358:TMATH RS04705
gene id: 583358:TMATH_RS04705
uniprot id: D7ANA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

583358:TMATH RS01565
gene id: 583358:TMATH_RS01565
uniprot id: D7ARU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

583358:TMATH RS11155
gene id: 583358:TMATH_RS11155
uniprot id: D7ATM2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583358:TMATH RS06635
gene id: 583358:TMATH_RS06635
uniprot id: D7APD3
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

583358:TMATH RS10685
gene id: 583358:TMATH_RS10685
uniprot id: D7AT09
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

583358:TMATH RS01705
gene id: 583358:TMATH_RS01705
uniprot id: D7ARX2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

583358:TMATH RS07220
gene id: 583358:TMATH_RS07220
uniprot id: D7APN9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

583358:TMATH RS05990
gene id: 583358:TMATH_RS05990
uniprot id: D7AP04
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

583358:TMATH RS08725
gene id: 583358:TMATH_RS08725
uniprot id: D7AQX3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

583358:TMATH RS04530
gene id: 583358:TMATH_RS04530
uniprot id: D7AN74
names: Similarity
messages: Belongs to the asparagine synthetase family.

583358:TMATH RS08060
gene id: 583358:TMATH_RS08060
uniprot id: D7AQ70
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

583358:TMATH RS08395
gene id: 583358:TMATH_RS08395
uniprot id: D7AQQ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

583358:TMATH RS04495
gene id: 583358:TMATH_RS04495
uniprot id: D7AN67
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

583358:TMATH RS07865
gene id: 583358:TMATH_RS07865
uniprot id: D7AQ30
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

583358:TMATH RS07850
gene id: 583358:TMATH_RS07850
uniprot id: D7AQ27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

583358:TMATH RS00970
gene id: 583358:TMATH_RS00970
uniprot id: D7AR62
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

583358:TMATH RS01820
gene id: 583358:TMATH_RS01820
uniprot id: D7ARZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

583358:TMATH RS05705
gene id: 583358:TMATH_RS05705
uniprot id: D7ANU7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

583358:TMATH RS03215
gene id: 583358:TMATH_RS03215
uniprot id: D7ATF3
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

583358:TMATH RS07475
gene id: 583358:TMATH_RS07475
uniprot id: D7APT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

583358:TMATH RS03635
gene id: 583358:TMATH_RS03635
uniprot id: D7ATW2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

583358:TMATH RS00200
gene id: 583358:TMATH_RS00200
uniprot id: D7AQE1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

583358:TMATH RS01615
gene id: 583358:TMATH_RS01615
uniprot id: D7ARV4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS05885
gene id: 583358:TMATH_RS05885
uniprot id: D7ANY3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

583358:TMATH RS06840
gene id: 583358:TMATH_RS06840
uniprot id: D7APH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS04000
gene id: 583358:TMATH_RS04000
uniprot id: D7AU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS09905
gene id: 583358:TMATH_RS09905
uniprot id: D7AS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

583358:TMATH RS07570
gene id: 583358:TMATH_RS07570
uniprot id: D7APV8
names: Similarity
messages: Belongs to the peptidase M18 family.

583358:TMATH RS09655
gene id: 583358:TMATH_RS09655
uniprot id: D7ARR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

583358:TMATH RS07320
gene id: 583358:TMATH_RS07320
uniprot id: D7APQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

583358:TMATH RS09680
gene id: 583358:TMATH_RS09680
uniprot id: D7AS47
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

583358:TMATH RS11375
gene id: 583358:TMATH_RS11375
uniprot id: D7ATR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

583358:TMATH RS06230
gene id: 583358:TMATH_RS06230
uniprot id: D7AP51
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS03455
gene id: 583358:TMATH_RS03455
uniprot id: D7ATS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

583358:TMATH RS06035
gene id: 583358:TMATH_RS06035
uniprot id: D7AP12
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

583358:TMATH RS08030
gene id: 583358:TMATH_RS08030
uniprot id: D7AQ64
names: Similarity
messages: Belongs to the HypD family.

583358:TMATH RS05505
gene id: 583358:TMATH_RS05505
uniprot id: D7ANQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS11350
gene id: 583358:TMATH_RS11350
uniprot id: D7ATR0
names: Similarity
messages: Belongs to the ParB family.

583358:TMATH RS00585
gene id: 583358:TMATH_RS00585
uniprot id: D7AQL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

583358:TMATH RS06155
gene id: 583358:TMATH_RS06155
uniprot id: D7AP36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

583358:TMATH RS02220
gene id: 583358:TMATH_RS02220
uniprot id: D7ASJ1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

583358:TMATH RS07030
gene id: 583358:TMATH_RS07030
uniprot id: D7APK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583358:TMATH RS04585
gene id: 583358:TMATH_RS04585
uniprot id: D7AN83
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

583358:TMATH RS09040
gene id: 583358:TMATH_RS09040
uniprot id: D7ARG4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09305
gene id: 583358:TMATH_RS09305
uniprot id: D7ARL2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

583358:TMATH RS03160
gene id: 583358:TMATH_RS03160
uniprot id: D7ATE2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS07655
gene id: 583358:TMATH_RS07655
uniprot id: D7APX4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS04120
gene id: 583358:TMATH_RS04120
uniprot id: D7AMZ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS02660
gene id: 583358:TMATH_RS02660
uniprot id: D7ASR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

583358:TMATH RS06905
gene id: 583358:TMATH_RS06905
uniprot id: D7API2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

583358:TMATH RS03675
gene id: 583358:TMATH_RS03675
uniprot id: D7ATW9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

583358:TMATH RS03095
gene id: 583358:TMATH_RS03095
uniprot id: D7ATD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

583358:TMATH RS06345
gene id: 583358:TMATH_RS06345
uniprot id: D7AP74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

583358:TMATH RS02880
gene id: 583358:TMATH_RS02880
uniprot id: D7AT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS03470
gene id: 583358:TMATH_RS03470
uniprot id: D7ATS9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

583358:TMATH RS09785
gene id: 583358:TMATH_RS09785
uniprot id: D7AS67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS11360
gene id: 583358:TMATH_RS11360
uniprot id: D7ATR2
names: Similarity
messages: Belongs to the ParB family.

583358:TMATH RS06145
gene id: 583358:TMATH_RS06145
uniprot id: D7AP34
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

583358:TMATH RS04125
gene id: 583358:TMATH_RS04125
uniprot id: D7AMZ5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

583358:TMATH RS01240
gene id: 583358:TMATH_RS01240
uniprot id: D7ARB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS08045
gene id: 583358:TMATH_RS08045
uniprot id: D7AQ67
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

583358:TMATH RS03170
gene id: 583358:TMATH_RS03170
uniprot id: D7ATE4
names: Similarity
messages: Belongs to the GARS family.

583358:TMATH RS06780
gene id: 583358:TMATH_RS06780
uniprot id: D7APG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

583358:TMATH RS09385
gene id: 583358:TMATH_RS09385
uniprot id: D7ARM5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

583358:TMATH RS11095
gene id: 583358:TMATH_RS11095
uniprot id: D7ATL1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS06495
gene id: 583358:TMATH_RS06495
uniprot id: D7APA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

583358:TMATH RS06425
gene id: 583358:TMATH_RS06425
uniprot id: D7AP90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

583358:TMATH RS05960
gene id: 583358:TMATH_RS05960
uniprot id: D7ANZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

583358:TMATH RS02530
gene id: 583358:TMATH_RS02530
uniprot id: D7ASP3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS08505
gene id: 583358:TMATH_RS08505
uniprot id: D7AQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS09870
gene id: 583358:TMATH_RS09870
uniprot id: D7AS84
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

583358:TMATH RS05685
gene id: 583358:TMATH_RS05685
uniprot id: D7ANU3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

583358:TMATH RS04865
gene id: 583358:TMATH_RS04865
uniprot id: D7ANE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

583358:TMATH RS05395
gene id: 583358:TMATH_RS05395
uniprot id: D7ANN5
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS09700
gene id: 583358:TMATH_RS09700
uniprot id: D7AS51
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

583358:TMATH RS01100
gene id: 583358:TMATH_RS01100
uniprot id: D7AR89
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583358:TMATH RS03825
gene id: 583358:TMATH_RS03825
uniprot id: D7ATZ5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

583358:TMATH RS07800
gene id: 583358:TMATH_RS07800
uniprot id: D7AQ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

583358:TMATH RS10465
gene id: 583358:TMATH_RS10465
uniprot id: D7ASW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

583358:TMATH RS03125
gene id: 583358:TMATH_RS03125
uniprot id: D7ATD5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

583358:TMATH RS10805
gene id: 583358:TMATH_RS10805
uniprot id: D7AT34
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

583358:TMATH RS00645
gene id: 583358:TMATH_RS00645
uniprot id: D7AQM3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

583358:TMATH RS01985
gene id: 583358:TMATH_RS01985
uniprot id: D7AS27
names: Similarity
messages: Belongs to the Fur family.

583358:TMATH RS03235
gene id: 583358:TMATH_RS03235
uniprot id: D7ATF6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

583358:TMATH RS06900
gene id: 583358:TMATH_RS06900
uniprot id: D7API1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

583358:TMATH RS09585
gene id: 583358:TMATH_RS09585
uniprot id: D7ARQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

583358:TMATH RS05460
gene id: 583358:TMATH_RS05460
uniprot id: D7ANP8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

583358:TMATH RS01470
gene id: 583358:TMATH_RS01470
uniprot id: D7ARS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

583358:TMATH RS06610
gene id: 583358:TMATH_RS06610
uniprot id: D7APC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

583358:TMATH RS01485
gene id: 583358:TMATH_RS01485
uniprot id: D7ARS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

583358:TMATH RS02095
gene id: 583358:TMATH_RS02095
uniprot id: D7AS46
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

583358:TMATH RS05735
gene id: 583358:TMATH_RS05735
uniprot id: D7ANV3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

583358:TMATH RS09880
gene id: 583358:TMATH_RS09880
uniprot id: D7AS86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

583358:TMATH RS10025
gene id: 583358:TMATH_RS10025
uniprot id: D7ASB4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS01325
gene id: 583358:TMATH_RS01325
uniprot id: D7ARD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

583358:TMATH RS05420
gene id: 583358:TMATH_RS05420
uniprot id: D7ANN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS06590
gene id: 583358:TMATH_RS06590
uniprot id: D7APC3
names: Similarity
messages: Belongs to the glutamine synthetase family.

583358:TMATH RS03920
gene id: 583358:TMATH_RS03920
uniprot id: D7AU14
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS07095
gene id: 583358:TMATH_RS07095
uniprot id: D7APL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

583358:TMATH RS04230
gene id: 583358:TMATH_RS04230
uniprot id: D7AN17
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS09220
gene id: 583358:TMATH_RS09220
uniprot id: D7ARK0
names: Similarity
messages: Belongs to the UPF0047 family.

583358:TMATH RS09645
gene id: 583358:TMATH_RS09645
uniprot id: D7ARR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

583358:TMATH RS05155
gene id: 583358:TMATH_RS05155
uniprot id: D7ANI9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583358:TMATH RS07915
gene id: 583358:TMATH_RS07915
uniprot id: D7AQ40
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

583358:TMATH RS08390
gene id: 583358:TMATH_RS08390
uniprot id: D7AQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS10790
gene id: 583358:TMATH_RS10790
uniprot id: D7AT31
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

583358:TMATH RS11180
gene id: 583358:TMATH_RS11180
uniprot id: D7ATM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

583358:TMATH RS00710
gene id: 583358:TMATH_RS00710
uniprot id: D7AQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

583358:TMATH RS01160
gene id: 583358:TMATH_RS01160
uniprot id: D7ARA1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583358:TMATH RS00700
gene id: 583358:TMATH_RS00700
uniprot id: D7AQN1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

583358:TMATH RS07245
gene id: 583358:TMATH_RS07245
uniprot id: D7APP3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

583358:TMATH RS05625
gene id: 583358:TMATH_RS05625
uniprot id: D7ANT1
names: Similarity
messages: Belongs to the peptidase M24B family.

583358:TMATH RS06795
gene id: 583358:TMATH_RS06795
uniprot id: D7APG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

583358:TMATH RS11025
gene id: 583358:TMATH_RS11025
uniprot id: D7ATJ6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

583358:TMATH RS07080
gene id: 583358:TMATH_RS07080
uniprot id: D7APL1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583358:TMATH RS05195
gene id: 583358:TMATH_RS05195
uniprot id: D7ANJ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS10760
gene id: 583358:TMATH_RS10760
uniprot id: D7AT24
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

583358:TMATH RS03010
gene id: 583358:TMATH_RS03010
uniprot id: D7ATB1
names: Similarity
messages: Belongs to the MotB family.

583358:TMATH RS07160
gene id: 583358:TMATH_RS07160
uniprot id: D7APM7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09075
gene id: 583358:TMATH_RS09075
uniprot id: D7ARH1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS05520
gene id: 583358:TMATH_RS05520
uniprot id: D7ANR0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

583358:TMATH RS03175
gene id: 583358:TMATH_RS03175
uniprot id: D7ATE5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

583358:TMATH RS08250
gene id: 583358:TMATH_RS08250
uniprot id: D7AQA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

583358:TMATH RS05795
gene id: 583358:TMATH_RS05795
uniprot id: D7ANW6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

583358:TMATH RS05700
gene id: 583358:TMATH_RS05700
uniprot id: D7ANU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

583358:TMATH RS04010
gene id: 583358:TMATH_RS04010
uniprot id: D7AU31
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

583358:TMATH RS04005
gene id: 583358:TMATH_RS04005
uniprot id: D7AU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06940
gene id: 583358:TMATH_RS06940
uniprot id: D7API9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

583358:TMATH RS09060
gene id: 583358:TMATH_RS09060
uniprot id: D7ARG8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

583358:TMATH RS05790
gene id: 583358:TMATH_RS05790
uniprot id: D7ANW5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

583358:TMATH RS01770
gene id: 583358:TMATH_RS01770
uniprot id: D7ARY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

583358:TMATH RS09715
gene id: 583358:TMATH_RS09715
uniprot id: D7AS54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

583358:TMATH RS10815
gene id: 583358:TMATH_RS10815
uniprot id: D7AT36
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

583358:TMATH RS08780
gene id: 583358:TMATH_RS08780
uniprot id: D7AQY4
names: Similarity
messages: Belongs to the peptidase S41A family.

583358:TMATH RS04075
gene id: 583358:TMATH_RS04075
uniprot id: D7AU44
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

583358:TMATH RS09335
gene id: 583358:TMATH_RS09335
uniprot id: D7ARL7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

583358:TMATH RS11060
gene id: 583358:TMATH_RS11060
uniprot id: D7ATK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

583358:TMATH RS11310
gene id: 583358:TMATH_RS11310
uniprot id: D7ATQ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

583358:TMATH RS02195
gene id: 583358:TMATH_RS02195
uniprot id: D7ASI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS10900
gene id: 583358:TMATH_RS10900
uniprot id: D7AT55
names: Similarity
messages: Belongs to the UPF0735 family.

583358:TMATH RS00240
gene id: 583358:TMATH_RS00240
uniprot id: D7AQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

583358:TMATH RS03525
gene id: 583358:TMATH_RS03525
uniprot id: D7ATU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06300
gene id: 583358:TMATH_RS06300
uniprot id: D7AP65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

583358:TMATH RS03865
gene id: 583358:TMATH_RS03865
uniprot id: D7AU03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS01960
gene id: 583358:TMATH_RS01960
uniprot id: D7AS22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

583358:TMATH RS05405
gene id: 583358:TMATH_RS05405
uniprot id: D7ANN7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583358:TMATH RS01275
gene id: 583358:TMATH_RS01275
uniprot id: D7ARC5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

583358:TMATH RS04845
gene id: 583358:TMATH_RS04845
uniprot id: D7AND7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS00520
gene id: 583358:TMATH_RS00520
uniprot id: D7AQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

583358:TMATH RS00775
gene id: 583358:TMATH_RS00775
uniprot id: D7AQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

583358:TMATH RS02510
gene id: 583358:TMATH_RS02510
uniprot id: D7ASN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS07315
gene id: 583358:TMATH_RS07315
uniprot id: D7APQ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS06240
gene id: 583358:TMATH_RS06240
uniprot id: D7AP53
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

583358:TMATH RS01290
gene id: 583358:TMATH_RS01290
uniprot id: D7ARC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06060
gene id: 583358:TMATH_RS06060
uniprot id: D7AP17
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

583358:TMATH RS06260
gene id: 583358:TMATH_RS06260
uniprot id: D7AP57
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

583358:TMATH RS06565
gene id: 583358:TMATH_RS06565
uniprot id: D7APB8
names: Similarity
messages: Belongs to the glutamate synthase family.

583358:TMATH RS06605
gene id: 583358:TMATH_RS06605
uniprot id: D7APC7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

583358:TMATH RS03230
gene id: 583358:TMATH_RS03230
uniprot id: D7ATF5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

583358:TMATH RS05345
gene id: 583358:TMATH_RS05345
uniprot id: D7ANM5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

583358:TMATH RS08530
gene id: 583358:TMATH_RS08530
uniprot id: D7AQT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

583358:TMATH RS05060
gene id: 583358:TMATH_RS05060
uniprot id: D7ANG9
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

583358:TMATH RS07835
gene id: 583358:TMATH_RS07835
uniprot id: D7AQ24
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

583358:TMATH RS10885
gene id: 583358:TMATH_RS10885
uniprot id: D7AT52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

583358:TMATH RS02475
gene id: 583358:TMATH_RS02475
uniprot id: D7ASN4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

583358:TMATH RS00715
gene id: 583358:TMATH_RS00715
uniprot id: D7AQN4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

583358:TMATH RS08585
gene id: 583358:TMATH_RS08585
uniprot id: D7AQU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

583358:TMATH RS08385
gene id: 583358:TMATH_RS08385
uniprot id: D7AQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS05615
gene id: 583358:TMATH_RS05615
uniprot id: D7ANS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

583358:TMATH RS06455
gene id: 583358:TMATH_RS06455
uniprot id: D7AP96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS03940
gene id: 583358:TMATH_RS03940
uniprot id: D7AU18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

583358:TMATH RS08630
gene id: 583358:TMATH_RS08630
uniprot id: D7AQV5
names: Similarity
messages: Belongs to the FGGY kinase family.

583358:TMATH RS08080
gene id: 583358:TMATH_RS08080
uniprot id: D7AQ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

583358:TMATH RS02140
gene id: 583358:TMATH_RS02140
uniprot id: D7ASH5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

583358:TMATH RS01000
gene id: 583358:TMATH_RS01000
uniprot id: D7AR68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS05545
gene id: 583358:TMATH_RS05545
uniprot id: D7ANR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS02675
gene id: 583358:TMATH_RS02675
uniprot id: D7ASS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

583358:TMATH RS10015
gene id: 583358:TMATH_RS10015
uniprot id: D7ASB2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

583358:TMATH RS09810
gene id: 583358:TMATH_RS09810
uniprot id: D7AS72
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

583358:TMATH RS06660
gene id: 583358:TMATH_RS06660
uniprot id: D7APD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS11320
gene id: 583358:TMATH_RS11320
uniprot id: D7ATQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583358:TMATH RS02075
gene id: 583358:TMATH_RS02075
uniprot id: D7AS42
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

583358:TMATH RS12040
gene id: 583358:TMATH_RS12040
uniprot id: D7APS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

583358:TMATH RS08815
gene id: 583358:TMATH_RS08815
uniprot id: D7AQZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

583358:TMATH RS01835
gene id: 583358:TMATH_RS01835
uniprot id: D7ARZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

583358:TMATH RS07990
gene id: 583358:TMATH_RS07990
uniprot id: D7AQ56
names: Similarity
messages: Belongs to the manganese catalase family.

583358:TMATH RS08210
gene id: 583358:TMATH_RS08210
uniprot id: D7AQA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

583358:TMATH RS03415
gene id: 583358:TMATH_RS03415
uniprot id: D7ATI1
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS06730
gene id: 583358:TMATH_RS06730
uniprot id: D7APF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

583358:TMATH RS10645
gene id: 583358:TMATH_RS10645
uniprot id: D7AT01
names: Similarity
messages: Belongs to the SleB family.

583358:TMATH RS06920
gene id: 583358:TMATH_RS06920
uniprot id: D7API5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

583358:TMATH RS07210
gene id: 583358:TMATH_RS07210
uniprot id: D7APN7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

583358:TMATH RS09835
gene id: 583358:TMATH_RS09835
uniprot id: D7AS77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

583358:TMATH RS09445
gene id: 583358:TMATH_RS09445
uniprot id: D7ARN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

583358:TMATH RS11275
gene id: 583358:TMATH_RS11275
uniprot id: D7ATP5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

583358:TMATH RS09190
gene id: 583358:TMATH_RS09190
uniprot id: D7ARJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

583358:TMATH RS06075
gene id: 583358:TMATH_RS06075
uniprot id: D7AP20
names: Similarity
messages: Belongs to the CinA family.

583358:TMATH RS04390
gene id: 583358:TMATH_RS04390
uniprot id: D7AN47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

583358:TMATH RS01320
gene id: 583358:TMATH_RS01320
uniprot id: D7ARD4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

583358:TMATH RS04680
gene id: 583358:TMATH_RS04680
uniprot id: D7ANA3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

583358:TMATH RS01260
gene id: 583358:TMATH_RS01260
uniprot id: D7ARC2
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

583358:TMATH RS07795
gene id: 583358:TMATH_RS07795
uniprot id: D7AQ18
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

583358:TMATH RS08000
gene id: 583358:TMATH_RS08000
uniprot id: D7AQ58
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

583358:TMATH RS11165
gene id: 583358:TMATH_RS11165
uniprot id: D7ATM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

583358:TMATH RS01790
gene id: 583358:TMATH_RS01790
uniprot id: D7ARY8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

583358:TMATH RS00020
gene id: 583358:TMATH_RS00020
uniprot id: D7APY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

583358:TMATH RS01990
gene id: 583358:TMATH_RS01990
uniprot id: D7AS28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

583358:TMATH RS03510
gene id: 583358:TMATH_RS03510
uniprot id: D7ATT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

583358:TMATH RS07805
gene id: 583358:TMATH_RS07805
uniprot id: D7AQ20
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

583358:TMATH RS03075
gene id: 583358:TMATH_RS03075
uniprot id: D7ATC5
names: Similarity
messages: Belongs to the peptidase S8 family.

583358:TMATH RS02955
gene id: 583358:TMATH_RS02955
uniprot id: D7ATA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS08160
gene id: 583358:TMATH_RS08160
uniprot id: D7AQ90
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

583358:TMATH RS03640
gene id: 583358:TMATH_RS03640
uniprot id: D7ATW3
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS09970
gene id: 583358:TMATH_RS09970
uniprot id: D7ASA2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

583358:TMATH RS08010
gene id: 583358:TMATH_RS08010
uniprot id: D7AQ60
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

583358:TMATH RS08445
gene id: 583358:TMATH_RS08445
uniprot id: D7AQR9
names: Similarity
messages: Belongs to the ribulokinase family.

583358:TMATH RS03240
gene id: 583358:TMATH_RS03240
uniprot id: D7ATF7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

583358:TMATH RS04380
gene id: 583358:TMATH_RS04380
uniprot id: D7AN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

583358:TMATH RS04485
gene id: 583358:TMATH_RS04485
uniprot id: D7AN66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS06505
gene id: 583358:TMATH_RS06505
uniprot id: D7APA6
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

583358:TMATH RS10715
gene id: 583358:TMATH_RS10715
uniprot id: D7AT15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

583358:TMATH RS01865
gene id: 583358:TMATH_RS01865
uniprot id: D7AS03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

583358:TMATH RS04115
gene id: 583358:TMATH_RS04115
uniprot id: D7AMZ3
names: Similarity
messages: Belongs to the glutamine synthetase family.

583358:TMATH RS00750
gene id: 583358:TMATH_RS00750
uniprot id: D7AQP1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

583358:TMATH RS01555
gene id: 583358:TMATH_RS01555
uniprot id: D7ARU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

583358:TMATH RS01165
gene id: 583358:TMATH_RS01165
uniprot id: D7ARA2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

583358:TMATH RS09690
gene id: 583358:TMATH_RS09690
uniprot id: D7AS49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

583358:TMATH RS10740
gene id: 583358:TMATH_RS10740
uniprot id: D7AT20
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS05730
gene id: 583358:TMATH_RS05730
uniprot id: D7ANV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

583358:TMATH RS07580
gene id: 583358:TMATH_RS07580
uniprot id: D7APW0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

583358:TMATH RS07415
gene id: 583358:TMATH_RS07415
uniprot id: D7APS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

583358:TMATH RS01110
gene id: 583358:TMATH_RS01110
uniprot id: D7AR91
names: Similarity
messages: Belongs to the UxaA family.

583358:TMATH RS09000
gene id: 583358:TMATH_RS09000
uniprot id: D7ARF6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

583358:TMATH RS00050
gene id: 583358:TMATH_RS00050
uniprot id: D7APY9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

583358:TMATH RS03495
gene id: 583358:TMATH_RS03495
uniprot id: D7ATT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

583358:TMATH RS09345
gene id: 583358:TMATH_RS09345
uniprot id: D7ARL9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

583358:TMATH RS07175
gene id: 583358:TMATH_RS07175
uniprot id: D7APN0
names: Subcellular Location Annotation
messages: Cytoplasm

583358:TMATH RS01175
gene id: 583358:TMATH_RS01175
uniprot id: D7ARA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

583358:TMATH RS11330
gene id: 583358:TMATH_RS11330
uniprot id: D7ATQ6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

583358:TMATH RS06120
gene id: 583358:TMATH_RS06120
uniprot id: D7AP29
names: Similarity
messages: Belongs to the peptidase M16 family.

583358:TMATH RS01995
gene id: 583358:TMATH_RS01995
uniprot id: D7AS29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583358:TMATH RS00635
gene id: 583358:TMATH_RS00635
uniprot id: D7AQM1
names: Similarity
messages: Belongs to the class-I fumarase family.

583358:TMATH RS08310
gene id: 583358:TMATH_RS08310
uniprot id: D7AQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

583358:TMATH RS02120
gene id: 583358:TMATH_RS02120
uniprot id: D7ASH1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

583358:TMATH RS07135
gene id: 583358:TMATH_RS07135
uniprot id: D7APM2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

583358:TMATH RS08255
gene id: 583358:TMATH_RS08255
uniprot id: D7AQB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09780
gene id: 583358:TMATH_RS09780
uniprot id: D7AS66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS01845
gene id: 583358:TMATH_RS01845
uniprot id: D7ARZ9
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS08100
gene id: 583358:TMATH_RS08100
uniprot id: D7AQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS02795
gene id: 583358:TMATH_RS02795
uniprot id: D7AT69
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

583358:TMATH RS05170
gene id: 583358:TMATH_RS05170
uniprot id: D7ANJ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS11305
gene id: 583358:TMATH_RS11305
uniprot id: D7ATQ1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

583358:TMATH RS00385
gene id: 583358:TMATH_RS00385
uniprot id: D7AQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

583358:TMATH RS07235
gene id: 583358:TMATH_RS07235
uniprot id: D7APP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

583358:TMATH RS10440
gene id: 583358:TMATH_RS10440
uniprot id: D7ASW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

583358:TMATH RS08200
gene id: 583358:TMATH_RS08200
uniprot id: D7AQ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS10655
gene id: 583358:TMATH_RS10655
uniprot id: D7AT03
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

583358:TMATH RS07395
gene id: 583358:TMATH_RS07395
uniprot id: D7APS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

583358:TMATH RS05190
gene id: 583358:TMATH_RS05190
uniprot id: D7ANJ5
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

583358:TMATH RS08005
gene id: 583358:TMATH_RS08005
uniprot id: D7AQ59
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

583358:TMATH RS05260
gene id: 583358:TMATH_RS05260
uniprot id: D7ANK7
names: Similarity
messages: Belongs to the IMPACT family.

583358:TMATH RS09570
gene id: 583358:TMATH_RS09570
uniprot id: D7ARP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

583358:TMATH RS01980
gene id: 583358:TMATH_RS01980
uniprot id: D7AS26
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

583358:TMATH RS04630
gene id: 583358:TMATH_RS04630
uniprot id: D7AN92
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS10020
gene id: 583358:TMATH_RS10020
uniprot id: D7ASB3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

583358:TMATH RS01970
gene id: 583358:TMATH_RS01970
uniprot id: D7AS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06385
gene id: 583358:TMATH_RS06385
uniprot id: D7AP82
names: Subcellular Location Annotation
messages: Cytoplasm

583358:TMATH RS04185
gene id: 583358:TMATH_RS04185
uniprot id: D7AN08
names: Similarity
messages: Belongs to the UPF0340 family.

583358:TMATH RS08870
gene id: 583358:TMATH_RS08870
uniprot id: D7AR01
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

583358:TMATH RS06925
gene id: 583358:TMATH_RS06925
uniprot id: D7API6
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

583358:TMATH RS03950
gene id: 583358:TMATH_RS03950
uniprot id: D7AU20
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

583358:TMATH RS03380
gene id: 583358:TMATH_RS03380
uniprot id: D7ATH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

583358:TMATH RS02560
gene id: 583358:TMATH_RS02560
uniprot id: D7ASP9
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS00465
gene id: 583358:TMATH_RS00465
uniprot id: D7AQJ4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

583358:TMATH RS08975
gene id: 583358:TMATH_RS08975
uniprot id: D7AR21
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

583358:TMATH RS00950
gene id: 583358:TMATH_RS00950
uniprot id: D7AR59
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS10755
gene id: 583358:TMATH_RS10755
uniprot id: D7AT23
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

583358:TMATH RS10370
gene id: 583358:TMATH_RS10370
uniprot id: D7ASU7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

583358:TMATH RS03890
gene id: 583358:TMATH_RS03890
uniprot id: D7AU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

583358:TMATH RS08730
gene id: 583358:TMATH_RS08730
uniprot id: D7AQX4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

583358:TMATH RS10390
gene id: 583358:TMATH_RS10390
uniprot id: D7ASV1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

583358:TMATH RS08535
gene id: 583358:TMATH_RS08535
uniprot id: D7AQT8
names: Similarity
messages: Belongs to the glycosyl hydrolase.

583358:TMATH RS09850
gene id: 583358:TMATH_RS09850
uniprot id: D7AS80
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

583358:TMATH RS03930
gene id: 583358:TMATH_RS03930
uniprot id: D7AU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

583358:TMATH RS00505
gene id: 583358:TMATH_RS00505
uniprot id: D7AQK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

583358:TMATH RS06815
gene id: 583358:TMATH_RS06815
uniprot id: D7APG9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS03870
gene id: 583358:TMATH_RS03870
uniprot id: D7AU04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

583358:TMATH RS09675
gene id: 583358:TMATH_RS09675
uniprot id: D7ARR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

583358:TMATH RS05805
gene id: 583358:TMATH_RS05805
uniprot id: D7ANW8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

583358:TMATH RS05970
gene id: 583358:TMATH_RS05970
uniprot id: D7AP00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

583358:TMATH RS09230
gene id: 583358:TMATH_RS09230
uniprot id: D7ARK2
names: Similarity
messages: Belongs to the PemK/MazF family.

583358:TMATH RS11055
gene id: 583358:TMATH_RS11055
uniprot id: D7ATK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

583358:TMATH RS03145
gene id: 583358:TMATH_RS03145
uniprot id: D7ATD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

583358:TMATH RS01815
gene id: 583358:TMATH_RS01815
uniprot id: D7ARZ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS05330
gene id: 583358:TMATH_RS05330
uniprot id: D7ANM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

583358:TMATH RS01030
gene id: 583358:TMATH_RS01030
uniprot id: D7AR74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS05115
gene id: 583358:TMATH_RS05115
uniprot id: D7ANI0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

583358:TMATH RS03480
gene id: 583358:TMATH_RS03480
uniprot id: D7ATT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

583358:TMATH RS06755
gene id: 583358:TMATH_RS06755
uniprot id: D7APF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

583358:TMATH RS01945
gene id: 583358:TMATH_RS01945
uniprot id: D7AS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS10620
gene id: 583358:TMATH_RS10620
uniprot id: D7ASZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS06085
gene id: 583358:TMATH_RS06085
uniprot id: D7AP22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

583358:TMATH RS09405
gene id: 583358:TMATH_RS09405
uniprot id: D7ARM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably a homodimer.

583358:TMATH RS05555
gene id: 583358:TMATH_RS05555
uniprot id: D7ANR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

583358:TMATH RS08750
gene id: 583358:TMATH_RS08750
uniprot id: D7AQX8
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS03115
gene id: 583358:TMATH_RS03115
uniprot id: D7ATD3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

583358:TMATH RS00030
gene id: 583358:TMATH_RS00030
uniprot id: D7APY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

583358:TMATH RS01360
gene id: 583358:TMATH_RS01360
uniprot id: D7ARE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS00010
gene id: 583358:TMATH_RS00010
uniprot id: D7APY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

583358:TMATH RS08635
gene id: 583358:TMATH_RS08635
uniprot id: D7AQV6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583358:TMATH RS02170
gene id: 583358:TMATH_RS02170
uniprot id: D7ASI1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

583358:TMATH RS10385
gene id: 583358:TMATH_RS10385
uniprot id: D7ASV0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

583358:TMATH RS00480
gene id: 583358:TMATH_RS00480
uniprot id: D7AQJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

583358:TMATH RS06405
gene id: 583358:TMATH_RS06405
uniprot id: D7AP86
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

583358:TMATH RS03110
gene id: 583358:TMATH_RS03110
uniprot id: D7ATD2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

583358:TMATH RS02515
gene id: 583358:TMATH_RS02515
uniprot id: D7ASP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS01715
gene id: 583358:TMATH_RS01715
uniprot id: D7ARX4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583358:TMATH RS04625
gene id: 583358:TMATH_RS04625
uniprot id: D7AN91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

583358:TMATH RS01190
gene id: 583358:TMATH_RS01190
uniprot id: D7ARA8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

583358:TMATH RS05275
gene id: 583358:TMATH_RS05275
uniprot id: D7ANL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS10850
gene id: 583358:TMATH_RS10850
uniprot id: D7AT43
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

583358:TMATH RS01875
gene id: 583358:TMATH_RS01875
uniprot id: D7AS05
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

583358:TMATH RS11030
gene id: 583358:TMATH_RS11030
uniprot id: D7ATJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

583358:TMATH RS05300
gene id: 583358:TMATH_RS05300
uniprot id: D7ANL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

583358:TMATH RS06515
gene id: 583358:TMATH_RS06515
uniprot id: D7APA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

583358:TMATH RS09590
gene id: 583358:TMATH_RS09590
uniprot id: D7ARQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

583358:TMATH RS11205
gene id: 583358:TMATH_RS11205
uniprot id: D7ATN3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

583358:TMATH RS08905
gene id: 583358:TMATH_RS08905
uniprot id: D7AR08
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

583358:TMATH RS00945
gene id: 583358:TMATH_RS00945
uniprot id: D7AR58
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

583358:TMATH RS08490
gene id: 583358:TMATH_RS08490
uniprot id: D7AQS9
names: Similarity
messages: Belongs to the aldose epimerase family.

583358:TMATH RS11400
gene id: 583358:TMATH_RS11400
uniprot id: D7ATS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

583358:TMATH RS04755
gene id: 583358:TMATH_RS04755
uniprot id: D7ANB8
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS02445
gene id: 583358:TMATH_RS02445
uniprot id: D7ASM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06185
gene id: 583358:TMATH_RS06185
uniprot id: D7AP42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

583358:TMATH RS05985
gene id: 583358:TMATH_RS05985
uniprot id: D7AP03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS04580
gene id: 583358:TMATH_RS04580
uniprot id: D7AN82
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

583358:TMATH RS10725
gene id: 583358:TMATH_RS10725
uniprot id: D7AT17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

583358:TMATH RS03830
gene id: 583358:TMATH_RS03830
uniprot id: D7ATZ6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

583358:TMATH RS05215
gene id: 583358:TMATH_RS05215
uniprot id: D7ANK0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

583358:TMATH RS05745
gene id: 583358:TMATH_RS05745
uniprot id: D7ANV5
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS07065
gene id: 583358:TMATH_RS07065
uniprot id: D7APK8
names: Similarity
messages: Belongs to the UPF0047 family.

583358:TMATH RS00005
gene id: 583358:TMATH_RS00005
uniprot id: D7APY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

583358:TMATH RS10925
gene id: 583358:TMATH_RS10925
uniprot id: D7AT60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

583358:TMATH RS05075
gene id: 583358:TMATH_RS05075
uniprot id: D7ANH2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

583358:TMATH RS05500
gene id: 583358:TMATH_RS05500
uniprot id: D7ANQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

583358:TMATH RS06365
gene id: 583358:TMATH_RS06365
uniprot id: D7AP78
names: Similarity
messages: Belongs to the FlgD family.

583358:TMATH RS01670
gene id: 583358:TMATH_RS01670
uniprot id: D7ARW5
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS10350
gene id: 583358:TMATH_RS10350
uniprot id: D7ASU3
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

583358:TMATH RS07340
gene id: 583358:TMATH_RS07340
uniprot id: D7APR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

583358:TMATH RS07230
gene id: 583358:TMATH_RS07230
uniprot id: D7APP0
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

583358:TMATH RS00160
gene id: 583358:TMATH_RS00160
uniprot id: D7AQD3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.

583358:TMATH RS09560
gene id: 583358:TMATH_RS09560
uniprot id: D7ARP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

583358:TMATH RS10115
gene id: 583358:TMATH_RS10115
uniprot id: D7ASD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

583358:TMATH RS10395
gene id: 583358:TMATH_RS10395
uniprot id: D7ASV2
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS11210
gene id: 583358:TMATH_RS11210
uniprot id: D7ATN4
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

583358:TMATH RS06430
gene id: 583358:TMATH_RS06430
uniprot id: D7AP91
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

583358:TMATH RS06910
gene id: 583358:TMATH_RS06910
uniprot id: D7API3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

583358:TMATH RS06175
gene id: 583358:TMATH_RS06175
uniprot id: D7AP40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

583358:TMATH RS07125
gene id: 583358:TMATH_RS07125
uniprot id: D7APM0
names: Similarity
messages: Belongs to the UPF0045 family.

583358:TMATH RS02850
gene id: 583358:TMATH_RS02850
uniprot id: D7AT79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

583358:TMATH RS00730
gene id: 583358:TMATH_RS00730
uniprot id: D7AQN7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

583358:TMATH RS07190
gene id: 583358:TMATH_RS07190
uniprot id: D7APN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

583358:TMATH RS09990
gene id: 583358:TMATH_RS09990
uniprot id: D7ASA8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

583358:TMATH RS10475
gene id: 583358:TMATH_RS10475
uniprot id: D7ASW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

583358:TMATH RS10450
gene id: 583358:TMATH_RS10450
uniprot id: D7ASW3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS06235
gene id: 583358:TMATH_RS06235
uniprot id: D7AP52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

583358:TMATH RS00210
gene id: 583358:TMATH_RS00210
uniprot id: D7AQE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583358:TMATH RS04180
gene id: 583358:TMATH_RS04180
uniprot id: D7AN07
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

583358:TMATH RS06400
gene id: 583358:TMATH_RS06400
uniprot id: D7AP85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

583358:TMATH RS07745
gene id: 583358:TMATH_RS07745
uniprot id: D7AQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

583358:TMATH RS02920
gene id: 583358:TMATH_RS02920
uniprot id: D7AT93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

583358:TMATH RS04830
gene id: 583358:TMATH_RS04830
uniprot id: D7AND4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

583358:TMATH RS03055
gene id: 583358:TMATH_RS03055
uniprot id: D7ATC1
names: Similarity
messages: Belongs to the glutamate synthase family.

583358:TMATH RS07420
gene id: 583358:TMATH_RS07420
uniprot id: D7APS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

583358:TMATH RS00310
gene id: 583358:TMATH_RS00310
uniprot id: D7AQG3
names: Similarity
messages: Belongs to the GSP E family.

583358:TMATH RS02165
gene id: 583358:TMATH_RS02165
uniprot id: D7ASI0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

583358:TMATH RS04700
gene id: 583358:TMATH_RS04700
uniprot id: D7ANA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

583358:TMATH RS00120
gene id: 583358:TMATH_RS00120
uniprot id: D7AQ01
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

583358:TMATH RS02135
gene id: 583358:TMATH_RS02135
uniprot id: D7ASH4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

583358:TMATH RS09565
gene id: 583358:TMATH_RS09565
uniprot id: D7ARP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

583358:TMATH RS01515
gene id: 583358:TMATH_RS01515
uniprot id: D7ART4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

583358:TMATH RS06080
gene id: 583358:TMATH_RS06080
uniprot id: D7AP21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

583358:TMATH RS09050
gene id: 583358:TMATH_RS09050
uniprot id: D7ARG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

583358:TMATH RS04785
gene id: 583358:TMATH_RS04785
uniprot id: D7ANC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

583358:TMATH RS02485
gene id: 583358:TMATH_RS02485
uniprot id: D7ASN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

583358:TMATH RS00040
gene id: 583358:TMATH_RS00040
uniprot id: D7APY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

583358:TMATH RS05280
gene id: 583358:TMATH_RS05280
uniprot id: D7ANL1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

583358:TMATH RS06580
gene id: 583358:TMATH_RS06580
uniprot id: D7APC1
names: Similarity
messages: Belongs to the P(II) protein family.

583358:TMATH RS03165
gene id: 583358:TMATH_RS03165
uniprot id: D7ATE3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

583358:TMATH RS06030
gene id: 583358:TMATH_RS06030
uniprot id: D7AP11
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

583358:TMATH RS00110
gene id: 583358:TMATH_RS00110
uniprot id: D7APZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

583358:TMATH RS08520
gene id: 583358:TMATH_RS08520
uniprot id: D7AQT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

583358:TMATH RS04645
gene id: 583358:TMATH_RS04645
uniprot id: D7AN96
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

583358:TMATH RS03040
gene id: 583358:TMATH_RS03040
uniprot id: D7ATB8
names: Similarity
messages: Belongs to the asp23 family.

583358:TMATH RS06930
gene id: 583358:TMATH_RS06930
uniprot id: D7API7
names: Similarity
messages: Belongs to the HypE family.

583358:TMATH RS06200
gene id: 583358:TMATH_RS06200
uniprot id: D7AP45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

583358:TMATH RS01850
gene id: 583358:TMATH_RS01850
uniprot id: D7AS00
names: Similarity
messages: Belongs to the UPF0111 family.

583358:TMATH RS03265
gene id: 583358:TMATH_RS03265
uniprot id: D7ATG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

583358:TMATH RS05490
gene id: 583358:TMATH_RS05490
uniprot id: D7ANQ4
names: Similarity
messages: Belongs to the UPF0342 family.

583358:TMATH RS04555
gene id: 583358:TMATH_RS04555
uniprot id: D7AN79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583358:TMATH RS03515
gene id: 583358:TMATH_RS03515
uniprot id: D7ATT9
names: Similarity
messages: Belongs to the EamA transporter family.

583358:TMATH RS06510
gene id: 583358:TMATH_RS06510
uniprot id: D7APA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

583358:TMATH RS06325
gene id: 583358:TMATH_RS06325
uniprot id: D7AP70
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

583358:TMATH RS06180
gene id: 583358:TMATH_RS06180
uniprot id: D7AP41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

583358:TMATH RS06845
gene id: 583358:TMATH_RS06845
uniprot id: D7APH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

583358:TMATH RS07650
gene id: 583358:TMATH_RS07650
uniprot id: D7APX3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS10880
gene id: 583358:TMATH_RS10880
uniprot id: D7AT51
names: Similarity
messages: Belongs to the peptidase S41A family.

583358:TMATH RS06825
gene id: 583358:TMATH_RS06825
uniprot id: D7APH1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

583358:TMATH RS03460
gene id: 583358:TMATH_RS03460
uniprot id: D7ATS7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

583358:TMATH RS08090
gene id: 583358:TMATH_RS08090
uniprot id: D7AQ76
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

583358:TMATH RS03485
gene id: 583358:TMATH_RS03485
uniprot id: D7ATT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

583358:TMATH RS05720
gene id: 583358:TMATH_RS05720
uniprot id: D7ANV0
names: Similarity
messages: Belongs to the TlyA family.

583358:TMATH RS06320
gene id: 583358:TMATH_RS06320
uniprot id: D7AP69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

583358:TMATH RS05385
gene id: 583358:TMATH_RS05385
uniprot id: D7ANN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS00165
gene id: 583358:TMATH_RS00165
uniprot id: D7AQD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

583358:TMATH RS06115
gene id: 583358:TMATH_RS06115
uniprot id: D7AP28
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

583358:TMATH RS03270
gene id: 583358:TMATH_RS03270
uniprot id: D7ATG3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

583358:TMATH RS07040
gene id: 583358:TMATH_RS07040
uniprot id: D7APK4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583358:TMATH RS08740
gene id: 583358:TMATH_RS08740
uniprot id: D7AQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

583358:TMATH RS10570
gene id: 583358:TMATH_RS10570
uniprot id: D7ASY6
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

583358:TMATH RS10920
gene id: 583358:TMATH_RS10920
uniprot id: D7AT59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

583358:TMATH RS06595
gene id: 583358:TMATH_RS06595
uniprot id: D7APC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

583358:TMATH RS00745
gene id: 583358:TMATH_RS00745
uniprot id: D7AQP0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

583358:TMATH RS01055
gene id: 583358:TMATH_RS01055
uniprot id: D7AR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

583358:TMATH RS09600
gene id: 583358:TMATH_RS09600
uniprot id: D7ARQ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

583358:TMATH RS05465
gene id: 583358:TMATH_RS05465
uniprot id: D7ANP9
names: Similarity
messages: Belongs to the UPF0297 family.

583358:TMATH RS00500
gene id: 583358:TMATH_RS00500
uniprot id: D7AQJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

583358:TMATH RS00460
gene id: 583358:TMATH_RS00460
uniprot id: D7AQJ3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

583358:TMATH RS01675
gene id: 583358:TMATH_RS01675
uniprot id: D7ARW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

583358:TMATH RS01235
gene id: 583358:TMATH_RS01235
uniprot id: D7ARB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS02995
gene id: 583358:TMATH_RS02995
uniprot id: D7ATA8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583358:TMATH RS02820
gene id: 583358:TMATH_RS02820
uniprot id: D7AT74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

583358:TMATH RS08855
gene id: 583358:TMATH_RS08855
uniprot id: D7AQZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

583358:TMATH RS08015
gene id: 583358:TMATH_RS08015
uniprot id: D7AQ61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS04690
gene id: 583358:TMATH_RS04690
uniprot id: D7ANA5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

583358:TMATH RS07840
gene id: 583358:TMATH_RS07840
uniprot id: D7AQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

583358:TMATH RS09025
gene id: 583358:TMATH_RS09025
uniprot id: D7ARG1
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS01475
gene id: 583358:TMATH_RS01475
uniprot id: D7ARS6
names: Similarity
messages: Belongs to the UPF0236 family.

583358:TMATH RS08270
gene id: 583358:TMATH_RS08270
uniprot id: D7AQB4
names: Similarity
messages: Belongs to the UPF0251 family.

583358:TMATH RS05440
gene id: 583358:TMATH_RS05440
uniprot id: D7ANP3
names: Similarity
messages: Belongs to the thioredoxin family.

583358:TMATH RS04410
gene id: 583358:TMATH_RS04410
uniprot id: D7AN51
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS04820
gene id: 583358:TMATH_RS04820
uniprot id: D7AND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

583358:TMATH RS08260
gene id: 583358:TMATH_RS08260
uniprot id: D7AQB2
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

583358:TMATH RS00185
gene id: 583358:TMATH_RS00185
uniprot id: D7AQD8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

583358:TMATH RS01590
gene id: 583358:TMATH_RS01590
uniprot id: D7ARU9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

583358:TMATH RS01510
gene id: 583358:TMATH_RS01510
uniprot id: D7ART3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS06420
gene id: 583358:TMATH_RS06420
uniprot id: D7AP89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

583358:TMATH RS04725
gene id: 583358:TMATH_RS04725
uniprot id: D7ANB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS07940
gene id: 583358:TMATH_RS07940
uniprot id: D7AQ45
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

583358:TMATH RS07215
gene id: 583358:TMATH_RS07215
uniprot id: D7APN8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

583358:TMATH RS11235
gene id: 583358:TMATH_RS11235
uniprot id: D7ATN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

583358:TMATH RS01575
gene id: 583358:TMATH_RS01575
uniprot id: D7ARU6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

583358:TMATH RS02960
gene id: 583358:TMATH_RS02960
uniprot id: D7ATA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

583358:TMATH RS08510
gene id: 583358:TMATH_RS08510
uniprot id: D7AQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06690
gene id: 583358:TMATH_RS06690
uniprot id: D7APE4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

583358:TMATH RS10005
gene id: 583358:TMATH_RS10005
uniprot id: D7ASB0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

583358:TMATH RS07635
gene id: 583358:TMATH_RS07635
uniprot id: D7APX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

583358:TMATH RS05310
gene id: 583358:TMATH_RS05310
uniprot id: D7ANL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

583358:TMATH RS10190
gene id: 583358:TMATH_RS10190
uniprot id: D7ASE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

583358:TMATH RS09705
gene id: 583358:TMATH_RS09705
uniprot id: D7AS52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

583358:TMATH RS04360
gene id: 583358:TMATH_RS04360
uniprot id: D7AN41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

583358:TMATH RS09725
gene id: 583358:TMATH_RS09725
uniprot id: D7AS56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

583358:TMATH RS04440
gene id: 583358:TMATH_RS04440
uniprot id: D7AN57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

583358:TMATH RS05035
gene id: 583358:TMATH_RS05035
uniprot id: D7ANG4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

583358:TMATH RS08760
gene id: 583358:TMATH_RS08760
uniprot id: D7AQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

583358:TMATH RS03015
gene id: 583358:TMATH_RS03015
uniprot id: D7ATB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

583358:TMATH RS04235
gene id: 583358:TMATH_RS04235
uniprot id: D7AN18
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS08985
gene id: 583358:TMATH_RS08985
uniprot id: D7AR23
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

583358:TMATH RS10445
gene id: 583358:TMATH_RS10445
uniprot id: D7ASW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS01210
gene id: 583358:TMATH_RS01210
uniprot id: D7ARB2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

583358:TMATH RS07380
gene id: 583358:TMATH_RS07380
uniprot id: D7APR9
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS05095
gene id: 583358:TMATH_RS05095
uniprot id: D7ANH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS07600
gene id: 583358:TMATH_RS07600
uniprot id: D7APW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

583358:TMATH RS08545
gene id: 583358:TMATH_RS08545
uniprot id: D7AQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS04740
gene id: 583358:TMATH_RS04740
uniprot id: D7ANB5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS05895
gene id: 583358:TMATH_RS05895
uniprot id: D7ANY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

583358:TMATH RS11390
gene id: 583358:TMATH_RS11390
uniprot id: D7ATR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

583358:TMATH RS09470
gene id: 583358:TMATH_RS09470
uniprot id: D7ARP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

583358:TMATH RS01860
gene id: 583358:TMATH_RS01860
uniprot id: D7AS02
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

583358:TMATH RS05145
gene id: 583358:TMATH_RS05145
uniprot id: D7ANI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583358:TMATH RS08715
gene id: 583358:TMATH_RS08715
uniprot id: D7AQX1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

583358:TMATH RS06650
gene id: 583358:TMATH_RS06650
uniprot id: D7APD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

583358:TMATH RS09965
gene id: 583358:TMATH_RS09965
uniprot id: D7ASA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS07880
gene id: 583358:TMATH_RS07880
uniprot id: D7AQ33
names: Similarity
messages: Belongs to the acylphosphatase family.

583358:TMATH RS10460
gene id: 583358:TMATH_RS10460
uniprot id: D7ASW5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

583358:TMATH RS07130
gene id: 583358:TMATH_RS07130
uniprot id: D7APM1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583358:TMATH RS05245
gene id: 583358:TMATH_RS05245
uniprot id: D7ANK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

583358:TMATH RS10360
gene id: 583358:TMATH_RS10360
uniprot id: D7ASU5
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS01070
gene id: 583358:TMATH_RS01070
uniprot id: D7AR83
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

583358:TMATH RS02965
gene id: 583358:TMATH_RS02965
uniprot id: D7ATA2
names: Similarity
messages: Belongs to the carbamate kinase family.

583358:TMATH RS08910
gene id: 583358:TMATH_RS08910
uniprot id: D7AR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

583358:TMATH RS01890
gene id: 583358:TMATH_RS01890
uniprot id: D7AS08
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

583358:TMATH RS07705
gene id: 583358:TMATH_RS07705
uniprot id: D7APX9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

583358:TMATH RS07165
gene id: 583358:TMATH_RS07165
uniprot id: D7APM8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

583358:TMATH RS10665
gene id: 583358:TMATH_RS10665
uniprot id: D7AT05
names: Similarity
messages: Belongs to the GerABKA family.

583358:TMATH RS05305
gene id: 583358:TMATH_RS05305
uniprot id: D7ANL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

583358:TMATH RS04670
gene id: 583358:TMATH_RS04670
uniprot id: D7ANA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

583358:TMATH RS10635
gene id: 583358:TMATH_RS10635
uniprot id: D7ASZ9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

583358:TMATH RS04085
gene id: 583358:TMATH_RS04085
uniprot id: D7AMY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

583358:TMATH RS08140
gene id: 583358:TMATH_RS08140
uniprot id: D7AQ86
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS05535
gene id: 583358:TMATH_RS05535
uniprot id: D7ANR3
names: Similarity
messages: Belongs to the GSP E family.

583358:TMATH RS08625
gene id: 583358:TMATH_RS08625
uniprot id: D7AQV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

583358:TMATH RS08560
gene id: 583358:TMATH_RS08560
uniprot id: D7AQU3
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

583358:TMATH RS09630
gene id: 583358:TMATH_RS09630
uniprot id: D7ARR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

583358:TMATH RS00860
gene id: 583358:TMATH_RS00860
uniprot id: D7AR40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

583358:TMATH RS09390
gene id: 583358:TMATH_RS09390
uniprot id: D7ARM6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

583358:TMATH RS10855
gene id: 583358:TMATH_RS10855
uniprot id: D7AT44
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

583358:TMATH RS04255
gene id: 583358:TMATH_RS04255
uniprot id: D7AN22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

583358:TMATH RS00880
gene id: 583358:TMATH_RS00880
uniprot id: D7AR44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583358:TMATH RS08650
gene id: 583358:TMATH_RS08650
uniprot id: D7AQV9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583358:TMATH RS03225
gene id: 583358:TMATH_RS03225
uniprot id: D7ATF4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

583358:TMATH RS09770
gene id: 583358:TMATH_RS09770
uniprot id: D7AS64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583358:TMATH RS09670
gene id: 583358:TMATH_RS09670
uniprot id: D7ARR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

583358:TMATH RS08125
gene id: 583358:TMATH_RS08125
uniprot id: D7AQ83
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

583358:TMATH RS10915
gene id: 583358:TMATH_RS10915
uniprot id: D7AT58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

583358:TMATH RS05920
gene id: 583358:TMATH_RS05920
uniprot id: D7ANZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

583358:TMATH RS01350
gene id: 583358:TMATH_RS01350
uniprot id: D7ARE0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

583358:TMATH RS09440
gene id: 583358:TMATH_RS09440
uniprot id: D7ARN5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

583358:TMATH RS05380
gene id: 583358:TMATH_RS05380
uniprot id: D7ANN2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

583358:TMATH RS01305
gene id: 583358:TMATH_RS01305
uniprot id: D7ARD1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

583358:TMATH RS06715
gene id: 583358:TMATH_RS06715
uniprot id: D7APE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

583358:TMATH RS08795
gene id: 583358:TMATH_RS08795
uniprot id: D7AQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

583358:TMATH RS04750
gene id: 583358:TMATH_RS04750
uniprot id: D7ANB7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

583358:TMATH RS06700
gene id: 583358:TMATH_RS06700
uniprot id: D7APE6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

583358:TMATH RS06100
gene id: 583358:TMATH_RS06100
uniprot id: D7AP25
names: Similarity
messages: Belongs to the peptidase S14 family.

583358:TMATH RS10365
gene id: 583358:TMATH_RS10365
uniprot id: D7ASU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

583358:TMATH RS06485
gene id: 583358:TMATH_RS06485
uniprot id: D7APA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

583358:TMATH RS10205
gene id: 583358:TMATH_RS10205
uniprot id: D7ASF0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

583358:TMATH RS02700
gene id: 583358:TMATH_RS02700
uniprot id: D7ASS6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS09625
gene id: 583358:TMATH_RS09625
uniprot id: D7ARQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

583358:TMATH RS04025
gene id: 583358:TMATH_RS04025
uniprot id: D7AU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS00170
gene id: 583358:TMATH_RS00170
uniprot id: D7AQD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

583358:TMATH RS06435
gene id: 583358:TMATH_RS06435
uniprot id: D7AP92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

583358:TMATH RS04615
gene id: 583358:TMATH_RS04615
uniprot id: D7AN89
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS10595
gene id: 583358:TMATH_RS10595
uniprot id: D7ASZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS00910
gene id: 583358:TMATH_RS00910
uniprot id: D7AR50
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS07360
gene id: 583358:TMATH_RS07360
uniprot id: D7APR5
names: Similarity
messages: Belongs to the UPF0749 family.

583358:TMATH RS02945
gene id: 583358:TMATH_RS02945
uniprot id: D7AT98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS02470
gene id: 583358:TMATH_RS02470
uniprot id: D7ASN3
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS06460
gene id: 583358:TMATH_RS06460
uniprot id: D7AP97
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS02555
gene id: 583358:TMATH_RS02555
uniprot id: D7ASP8
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS07300
gene id: 583358:TMATH_RS07300
uniprot id: D7APQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

583358:TMATH RS04695
gene id: 583358:TMATH_RS04695
uniprot id: D7ANA6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

583358:TMATH RS01830
gene id: 583358:TMATH_RS01830
uniprot id: D7ARZ6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

583358:TMATH RS08300
gene id: 583358:TMATH_RS08300
uniprot id: D7AQC0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

583358:TMATH RS04400
gene id: 583358:TMATH_RS04400
uniprot id: D7AN49
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

583358:TMATH RS10630
gene id: 583358:TMATH_RS10630
uniprot id: D7ASZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

583358:TMATH RS05600
gene id: 583358:TMATH_RS05600
uniprot id: D7ANS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583358:TMATH RS04870
gene id: 583358:TMATH_RS04870
uniprot id: D7ANE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

583358:TMATH RS01035
gene id: 583358:TMATH_RS01035
uniprot id: D7AR75
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

583358:TMATH RS11285
gene id: 583358:TMATH_RS11285
uniprot id: D7ATP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

583358:TMATH RS08995
gene id: 583358:TMATH_RS08995
uniprot id: D7ARF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

583358:TMATH RS09295
gene id: 583358:TMATH_RS09295
uniprot id: D7ARL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

583358:TMATH RS08130
gene id: 583358:TMATH_RS08130
uniprot id: D7AQ84
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

583358:TMATH RS08935
gene id: 583358:TMATH_RS08935
uniprot id: D7AR14
names: Similarity
messages: Belongs to the phosphohexose mutase family.

583358:TMATH RS08050
gene id: 583358:TMATH_RS08050
uniprot id: D7AQ68
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

583358:TMATH RS09815
gene id: 583358:TMATH_RS09815
uniprot id: D7AS73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

583358:TMATH RS08220
gene id: 583358:TMATH_RS08220
uniprot id: D7AQA2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

583358:TMATH RS05900
gene id: 583358:TMATH_RS05900
uniprot id: D7ANY6
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

583358:TMATH RS06315
gene id: 583358:TMATH_RS06315
uniprot id: D7AP68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

583358:TMATH RS01650
gene id: 583358:TMATH_RS01650
uniprot id: D7ARW1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583358:TMATH RS01295
gene id: 583358:TMATH_RS01295
uniprot id: D7ARC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06490
gene id: 583358:TMATH_RS06490
uniprot id: D7APA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

583358:TMATH RS03540
gene id: 583358:TMATH_RS03540
uniprot id: D7ATU4
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS08940
gene id: 583358:TMATH_RS08940
uniprot id: D7AR15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS03400
gene id: 583358:TMATH_RS03400
uniprot id: D7ATH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

583358:TMATH RS09595
gene id: 583358:TMATH_RS09595
uniprot id: D7ARQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

583358:TMATH RS01965
gene id: 583358:TMATH_RS01965
uniprot id: D7AS23
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

583358:TMATH RS08595
gene id: 583358:TMATH_RS08595
uniprot id: D7AQV0
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS06410
gene id: 583358:TMATH_RS06410
uniprot id: D7AP87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

583358:TMATH RS03880
gene id: 583358:TMATH_RS03880
uniprot id: D7AU06
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS01130
gene id: 583358:TMATH_RS01130
uniprot id: D7AR95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583358:TMATH RS10535
gene id: 583358:TMATH_RS10535
uniprot id: D7ASX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

583358:TMATH RS08120
gene id: 583358:TMATH_RS08120
uniprot id: D7AQ82
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS06355
gene id: 583358:TMATH_RS06355
uniprot id: D7AP76
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

583358:TMATH RS11200
gene id: 583358:TMATH_RS11200
uniprot id: D7ATN2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

583358:TMATH RS05840
gene id: 583358:TMATH_RS05840
uniprot id: D7ANX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS00815
gene id: 583358:TMATH_RS00815
uniprot id: D7AR31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS11195
gene id: 583358:TMATH_RS11195
uniprot id: D7ATN1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

583358:TMATH RS03385
gene id: 583358:TMATH_RS03385
uniprot id: D7ATH5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

583358:TMATH RS04710
gene id: 583358:TMATH_RS04710
uniprot id: D7ANA9
names: Similarity
messages: Belongs to the UPF0237 family.

583358:TMATH RS00940
gene id: 583358:TMATH_RS00940
uniprot id: D7AR57
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

583358:TMATH RS08980
gene id: 583358:TMATH_RS08980
uniprot id: D7AR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

583358:TMATH RS00875
gene id: 583358:TMATH_RS00875
uniprot id: D7AR43
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

583358:TMATH RS06445
gene id: 583358:TMATH_RS06445
uniprot id: D7AP94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

583358:TMATH RS04385
gene id: 583358:TMATH_RS04385
uniprot id: D7AN46
names: Similarity
messages: Belongs to the transpeptidase family.

583358:TMATH RS03750
gene id: 583358:TMATH_RS03750
uniprot id: D7ATY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

583358:TMATH RS03210
gene id: 583358:TMATH_RS03210
uniprot id: D7ATF2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

583358:TMATH RS00955
gene id: 583358:TMATH_RS00955
uniprot id: D7AR60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

583358:TMATH RS02875
gene id: 583358:TMATH_RS02875
uniprot id: D7AT84
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

583358:TMATH RS04330
gene id: 583358:TMATH_RS04330
uniprot id: D7AN35
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

583358:TMATH RS05475
gene id: 583358:TMATH_RS05475
uniprot id: D7ANQ1
names: Similarity
messages: Belongs to the UPF0473 family.

583358:TMATH RS06070
gene id: 583358:TMATH_RS06070
uniprot id: D7AP19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

583358:TMATH RS02505
gene id: 583358:TMATH_RS02505
uniprot id: D7ASN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

583358:TMATH RS01335
gene id: 583358:TMATH_RS01335
uniprot id: D7ARD7
names: Subcellular Location Annotation
messages: Membrane

583358:TMATH RS10565
gene id: 583358:TMATH_RS10565
uniprot id: D7ASY5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

583358:TMATH RS00915
gene id: 583358:TMATH_RS00915
uniprot id: D7AR52
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

583358:TMATH RS10055
gene id: 583358:TMATH_RS10055
uniprot id: D7ASC0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

583358:TMATH RS09820
gene id: 583358:TMATH_RS09820
uniprot id: D7AS74
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

583358:TMATH RS00725
gene id: 583358:TMATH_RS00725
uniprot id: D7AQN6
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

583358:TMATH RS02105
gene id: 583358:TMATH_RS02105
uniprot id: D7ASG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

583358:TMATH RS09330
gene id: 583358:TMATH_RS09330
uniprot id: D7ARL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

583358:TMATH RS02770
gene id: 583358:TMATH_RS02770
uniprot id: D7AT64
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

583358:TMATH RS09550
gene id: 583358:TMATH_RS09550
uniprot id: D7ARP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

583358:TMATH RS00930
gene id: 583358:TMATH_RS00930
uniprot id: D7AR55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

583358:TMATH RS11170
gene id: 583358:TMATH_RS11170
uniprot id: D7ATM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

583358:TMATH RS01505
gene id: 583358:TMATH_RS01505
uniprot id: D7ART2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

583358:TMATH RS03335
gene id: 583358:TMATH_RS03335
uniprot id: D7ATG6
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

583358:TMATH RS00235
gene id: 583358:TMATH_RS00235
uniprot id: D7AQE7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

583358:TMATH RS10710
gene id: 583358:TMATH_RS10710
uniprot id: D7AT14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

583358:TMATH RS05325
gene id: 583358:TMATH_RS05325
uniprot id: D7ANM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

583358:TMATH RS08575
gene id: 583358:TMATH_RS08575
uniprot id: D7AQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

583358:TMATH RS10060
gene id: 583358:TMATH_RS10060
uniprot id: D7ASC1
names: Similarity
messages: Belongs to the GerABKA family.

583358:TMATH RS01810
gene id: 583358:TMATH_RS01810
uniprot id: D7ARZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

583358:TMATH RS07355
gene id: 583358:TMATH_RS07355
uniprot id: D7APR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

583358:TMATH RS07890
gene id: 583358:TMATH_RS07890
uniprot id: D7AQ35
names: Similarity
messages: Belongs to the Fur family.

583358:TMATH RS11020
gene id: 583358:TMATH_RS11020
uniprot id: D7ATJ5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

583358:TMATH RS02890
gene id: 583358:TMATH_RS02890
uniprot id: D7AT87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

583358:TMATH RS03360
gene id: 583358:TMATH_RS03360
uniprot id: D7ATH1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

583358:TMATH RS04285
gene id: 583358:TMATH_RS04285
uniprot id: D7AN26
names: Similarity
messages: Belongs to the peptidase C40 family.

583358:TMATH RS07105
gene id: 583358:TMATH_RS07105
uniprot id: D7APL6
names: Similarity
messages: Belongs to the TrpC family.

583358:TMATH RS08035
gene id: 583358:TMATH_RS08035
uniprot id: D7AQ65
names: Similarity
messages: Belongs to the HupF/HypC family.

583358:TMATH RS02800
gene id: 583358:TMATH_RS02800
uniprot id: D7AT70
names: Similarity
messages: Belongs to the bacterial flagellin family.

583358:TMATH RS06735
gene id: 583358:TMATH_RS06735
uniprot id: D7APF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

583358:TMATH RS09940
gene id: 583358:TMATH_RS09940
uniprot id: D7AS97
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

583358:TMATH RS04815
gene id: 583358:TMATH_RS04815
uniprot id: D7AND1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

583358:TMATH RS00895
gene id: 583358:TMATH_RS00895
uniprot id: D7AR47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583358:TMATH RS06600
gene id: 583358:TMATH_RS06600
uniprot id: D7APC6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

583358:TMATH RS08135
gene id: 583358:TMATH_RS08135
uniprot id: D7AQ85
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

583358:TMATH RS09580
gene id: 583358:TMATH_RS09580
uniprot id: D7ARQ0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

583358:TMATH RS08205
gene id: 583358:TMATH_RS08205
uniprot id: D7AQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

583358:TMATH RS06090
gene id: 583358:TMATH_RS06090
uniprot id: D7AP23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

583358:TMATH RS05360
gene id: 583358:TMATH_RS05360
uniprot id: D7ANM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

583358:TMATH RS08540
gene id: 583358:TMATH_RS08540
uniprot id: D7AQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS06810
gene id: 583358:TMATH_RS06810
uniprot id: D7APG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS06450
gene id: 583358:TMATH_RS06450
uniprot id: D7AP95
names: Similarity
messages: Belongs to the UPF0102 family.

583358:TMATH RS09620
gene id: 583358:TMATH_RS09620
uniprot id: D7ARQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

583358:TMATH RS10860
gene id: 583358:TMATH_RS10860
uniprot id: D7AT45
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

583358:TMATH RS01195
gene id: 583358:TMATH_RS01195
uniprot id: D7ARA9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

583358:TMATH RS02665
gene id: 583358:TMATH_RS02665
uniprot id: D7ASR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

583358:TMATH RS05270
gene id: 583358:TMATH_RS05270
uniprot id: D7ANK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS01690
gene id: 583358:TMATH_RS01690
uniprot id: D7ARW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

583358:TMATH RS03475
gene id: 583358:TMATH_RS03475
uniprot id: D7ATT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

583358:TMATH RS06020
gene id: 583358:TMATH_RS06020
uniprot id: D7AP09
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

583358:TMATH RS08475
gene id: 583358:TMATH_RS08475
uniprot id: D7AQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583358:TMATH RS07185
gene id: 583358:TMATH_RS07185
uniprot id: D7APN2
names: Similarity
messages: Belongs to the YggT family.

583358:TMATH RS05110
gene id: 583358:TMATH_RS05110
uniprot id: D7ANH9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

583358:TMATH RS05480
gene id: 583358:TMATH_RS05480
uniprot id: D7ANQ2
names: Similarity
messages: Belongs to the Fur family.

583358:TMATH RS04685
gene id: 583358:TMATH_RS04685
uniprot id: D7ANA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

583358:TMATH RS03860
gene id: 583358:TMATH_RS03860
uniprot id: D7AU02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

583358:TMATH RS07825
gene id: 583358:TMATH_RS07825
uniprot id: D7AQ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

583358:TMATH RS06340
gene id: 583358:TMATH_RS06340
uniprot id: D7AP73
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

583358:TMATH RS03505
gene id: 583358:TMATH_RS03505
uniprot id: D7ATT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

583358:TMATH RS05930
gene id: 583358:TMATH_RS05930
uniprot id: D7ANZ2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

583358:TMATH RS04295
gene id: 583358:TMATH_RS04295
uniprot id: D7AN28
names: Similarity
messages: Belongs to the transglycosylase Slt family.

583358:TMATH RS02060
gene id: 583358:TMATH_RS02060
uniprot id: D7AS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

583358:TMATH RS04345
gene id: 583358:TMATH_RS04345
uniprot id: D7AN38
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

583358:TMATH RS11345
gene id: 583358:TMATH_RS11345
uniprot id: D7ATQ9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

583358:TMATH RS05425
gene id: 583358:TMATH_RS05425
uniprot id: D7ANP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS09875
gene id: 583358:TMATH_RS09875
uniprot id: D7AS85
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

583358:TMATH RS06775
gene id: 583358:TMATH_RS06775
uniprot id: D7APG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

583358:TMATH RS01545
gene id: 583358:TMATH_RS01545
uniprot id: D7ARU0
names: Similarity
messages: Belongs to the hemerythrin family.

583358:TMATH RS05125
gene id: 583358:TMATH_RS05125
uniprot id: D7ANI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583358:TMATH RS03520
gene id: 583358:TMATH_RS03520
uniprot id: D7ATU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.