583355:CAKA RS12780
gene id: 583355:CAKA_RS12780
uniprot id: D5EP78
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

583355:CAKA RS10225
gene id: 583355:CAKA_RS10225
uniprot id: D5ELE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

583355:CAKA RS11380
gene id: 583355:CAKA_RS11380
uniprot id: D5EMR9
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS04100
gene id: 583355:CAKA_RS04100
uniprot id: D5EQ95
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

583355:CAKA RS07680
gene id: 583355:CAKA_RS07680
uniprot id: D5EJH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

583355:CAKA RS09160
gene id: 583355:CAKA_RS09160
uniprot id: D5EKB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

583355:CAKA RS09600
gene id: 583355:CAKA_RS09600
uniprot id: D5EKP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS03930
gene id: 583355:CAKA_RS03930
uniprot id: D5EQ62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS00780
gene id: 583355:CAKA_RS00780
uniprot id: D5EL90
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

583355:CAKA RS10810
gene id: 583355:CAKA_RS10810
uniprot id: D5EM36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

583355:CAKA RS07820
gene id: 583355:CAKA_RS07820
uniprot id: D5EJK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS15270
gene id: 583355:CAKA_RS15270
uniprot id: D5EI47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

583355:CAKA RS12120
gene id: 583355:CAKA_RS12120
uniprot id: D5ENI0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

583355:CAKA RS04190
gene id: 583355:CAKA_RS04190
uniprot id: D5EQB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

583355:CAKA RS10235
gene id: 583355:CAKA_RS10235
uniprot id: D5ELE2
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

583355:CAKA RS05070
gene id: 583355:CAKA_RS05070
uniprot id: D5EHM5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

583355:CAKA RS03010
gene id: 583355:CAKA_RS03010
uniprot id: D5ENZ1
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS01740
gene id: 583355:CAKA_RS01740
uniprot id: D5EMI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

583355:CAKA RS12340
gene id: 583355:CAKA_RS12340
uniprot id: D5ENM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

583355:CAKA RS06225
gene id: 583355:CAKA_RS06225
uniprot id: D5EIN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583355:CAKA RS08790
gene id: 583355:CAKA_RS08790
uniprot id: D5EK44
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS11875
gene id: 583355:CAKA_RS11875
uniprot id: D5END1
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS00800
gene id: 583355:CAKA_RS00800
uniprot id: D5ELM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

583355:CAKA RS05565
gene id: 583355:CAKA_RS05565
uniprot id: D5EI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583355:CAKA RS00770
gene id: 583355:CAKA_RS00770
uniprot id: D5EL88
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

583355:CAKA RS10035
gene id: 583355:CAKA_RS10035
uniprot id: D5ELA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

583355:CAKA RS03515
gene id: 583355:CAKA_RS03515
uniprot id: D5EPL0
names: Similarity
messages: Belongs to the thioredoxin family.

583355:CAKA RS03320
gene id: 583355:CAKA_RS03320
uniprot id: D5EPH1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

583355:CAKA RS03900
gene id: 583355:CAKA_RS03900
uniprot id: D5EQ56
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

583355:CAKA RS07695
gene id: 583355:CAKA_RS07695
uniprot id: D5EJH3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS09370
gene id: 583355:CAKA_RS09370
uniprot id: D5EKJ8
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

583355:CAKA RS05205
gene id: 583355:CAKA_RS05205
uniprot id: D5EHQ2
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

583355:CAKA RS10470
gene id: 583355:CAKA_RS10470
uniprot id: D5ELJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

583355:CAKA RS09110
gene id: 583355:CAKA_RS09110
uniprot id: D5EKA4
names: Similarity
messages: Belongs to the RecJ family.

583355:CAKA RS07870
gene id: 583355:CAKA_RS07870
uniprot id: D5EJL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

583355:CAKA RS11685
gene id: 583355:CAKA_RS11685
uniprot id: D5EMY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

583355:CAKA RS01050
gene id: 583355:CAKA_RS01050
uniprot id: D5ELS3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

583355:CAKA RS15055
gene id: 583355:CAKA_RS15055
uniprot id: D5EI02
names: Similarity
messages: Belongs to the UPRTase family.

583355:CAKA RS05860
gene id: 583355:CAKA_RS05860
uniprot id: D5EIF4
names: Similarity
messages: Belongs to the universal stress protein A family.

583355:CAKA RS01150
gene id: 583355:CAKA_RS01150
uniprot id: D5ELU5
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS03550
gene id: 583355:CAKA_RS03550
uniprot id: D5EPL7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

583355:CAKA RS13190
gene id: 583355:CAKA_RS13190
uniprot id: D5EPT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

583355:CAKA RS05035
gene id: 583355:CAKA_RS05035
uniprot id: D5EHL7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

583355:CAKA RS10865
gene id: 583355:CAKA_RS10865
uniprot id: D5EM46
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS09115
gene id: 583355:CAKA_RS09115
uniprot id: D5EKA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

583355:CAKA RS07790
gene id: 583355:CAKA_RS07790
uniprot id: D5EJJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS11100
gene id: 583355:CAKA_RS11100
uniprot id: D5EM90
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

583355:CAKA RS08045
gene id: 583355:CAKA_RS08045
uniprot id: D5EJP5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

583355:CAKA RS02970
gene id: 583355:CAKA_RS02970
uniprot id: D5ENY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583355:CAKA RS03400
gene id: 583355:CAKA_RS03400
uniprot id: D5EPI6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

583355:CAKA RS07845
gene id: 583355:CAKA_RS07845
uniprot id: D5EJK5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

583355:CAKA RS07690
gene id: 583355:CAKA_RS07690
uniprot id: D5EJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

583355:CAKA RS08725
gene id: 583355:CAKA_RS08725
uniprot id: D5EK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

583355:CAKA RS07075
gene id: 583355:CAKA_RS07075
uniprot id: D5EJ54
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS06975
gene id: 583355:CAKA_RS06975
uniprot id: D5EJ34
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583355:CAKA RS13600
gene id: 583355:CAKA_RS13600
uniprot id: D5EQ18
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS15065
gene id: 583355:CAKA_RS15065
uniprot id: D5EI04
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

583355:CAKA RS05870
gene id: 583355:CAKA_RS05870
uniprot id: D5EIF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

583355:CAKA RS14850
gene id: 583355:CAKA_RS14850
uniprot id: D5ERF6
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS10205
gene id: 583355:CAKA_RS10205
uniprot id: D5ELD6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

583355:CAKA RS16015
gene id: 583355:CAKA_RS16015
uniprot id: D5EJL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583355:CAKA RS05255
gene id: 583355:CAKA_RS05255
uniprot id: D5EHR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

583355:CAKA RS14515
gene id: 583355:CAKA_RS14515
uniprot id: D5ER88
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583355:CAKA RS08460
gene id: 583355:CAKA_RS08460
uniprot id: D5EJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

583355:CAKA RS06625
gene id: 583355:CAKA_RS06625
uniprot id: D5EIW2
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07990
gene id: 583355:CAKA_RS07990
uniprot id: D5EJN4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

583355:CAKA RS01260
gene id: 583355:CAKA_RS01260
uniprot id: D5ELW8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

583355:CAKA RS03490
gene id: 583355:CAKA_RS03490
uniprot id: D5EPK5
names: Similarity
messages: Belongs to the UxaA family.

583355:CAKA RS12005
gene id: 583355:CAKA_RS12005
uniprot id: D5ENF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

583355:CAKA RS04105
gene id: 583355:CAKA_RS04105
uniprot id: D5EQ96
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS10015
gene id: 583355:CAKA_RS10015
uniprot id: D5EL98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

583355:CAKA RS01065
gene id: 583355:CAKA_RS01065
uniprot id: D5ELS6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

583355:CAKA RS13510
gene id: 583355:CAKA_RS13510
uniprot id: D5EQ00
names: Similarity
messages: Belongs to the UPF0502 family.

583355:CAKA RS10050
gene id: 583355:CAKA_RS10050
uniprot id: D5ELA5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

583355:CAKA RS13515
gene id: 583355:CAKA_RS13515
uniprot id: D5EQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

583355:CAKA RS00765
gene id: 583355:CAKA_RS00765
uniprot id: D5EL87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

583355:CAKA RS03260
gene id: 583355:CAKA_RS03260
uniprot id: D5EPG2
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS14500
gene id: 583355:CAKA_RS14500
uniprot id: D5ER85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

583355:CAKA RS14970
gene id: 583355:CAKA_RS14970
uniprot id: D5EHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583355:CAKA RS03145
gene id: 583355:CAKA_RS03145
uniprot id: D5EPD9
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS03185
gene id: 583355:CAKA_RS03185
uniprot id: D5EPE7
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS15260
gene id: 583355:CAKA_RS15260
uniprot id: D5EI45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS00200
gene id: 583355:CAKA_RS00200
uniprot id: D5EKI9
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS03840
gene id: 583355:CAKA_RS03840
uniprot id: D5EQ44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS08910
gene id: 583355:CAKA_RS08910
uniprot id: D5EK68
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

583355:CAKA RS01580
gene id: 583355:CAKA_RS01580
uniprot id: D5EMF1
names: Similarity
messages: Belongs to the MoaD family.

583355:CAKA RS04335
gene id: 583355:CAKA_RS04335
uniprot id: D5EQE3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

583355:CAKA RS03125
gene id: 583355:CAKA_RS03125
uniprot id: D5EPD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583355:CAKA RS08500
gene id: 583355:CAKA_RS08500
uniprot id: D5EJY5
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS09245
gene id: 583355:CAKA_RS09245
uniprot id: D5EKD1
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS06280
gene id: 583355:CAKA_RS06280
uniprot id: D5EIP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

583355:CAKA RS08340
gene id: 583355:CAKA_RS08340
uniprot id: D5EJV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

583355:CAKA RS13925
gene id: 583355:CAKA_RS13925
uniprot id: D5EQJ9
names: Similarity
messages: Belongs to the peptidase S8 family.

583355:CAKA RS12230
gene id: 583355:CAKA_RS12230
uniprot id: D5ENK1
names: Similarity
messages: Belongs to the universal stress protein A family.

583355:CAKA RS11060
gene id: 583355:CAKA_RS11060
uniprot id: D5EM82
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

583355:CAKA RS01780
gene id: 583355:CAKA_RS01780
uniprot id: D5EMJ2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS14530
gene id: 583355:CAKA_RS14530
uniprot id: D5ER91
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

583355:CAKA RS03565
gene id: 583355:CAKA_RS03565
uniprot id: D5EPM0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

583355:CAKA RS11280
gene id: 583355:CAKA_RS11280
uniprot id: D5EMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583355:CAKA RS10130
gene id: 583355:CAKA_RS10130
uniprot id: D5ELC1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

583355:CAKA RS02300
gene id: 583355:CAKA_RS02300
uniprot id: D5EN67
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS07255
gene id: 583355:CAKA_RS07255
uniprot id: D5EJ89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

583355:CAKA RS07555
gene id: 583355:CAKA_RS07555
uniprot id: D5EJE7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

583355:CAKA RS08285
gene id: 583355:CAKA_RS08285
uniprot id: D5EJU2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

583355:CAKA RS03415
gene id: 583355:CAKA_RS03415
uniprot id: D5EPJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583355:CAKA RS12815
gene id: 583355:CAKA_RS12815
uniprot id: D5EP85
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS12720
gene id: 583355:CAKA_RS12720
uniprot id: D5EP66
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

583355:CAKA RS04140
gene id: 583355:CAKA_RS04140
uniprot id: D5EQA3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

583355:CAKA RS00395
gene id: 583355:CAKA_RS00395
uniprot id: D5EL08
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

583355:CAKA RS10340
gene id: 583355:CAKA_RS10340
uniprot id: D5ELG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

583355:CAKA RS14955
gene id: 583355:CAKA_RS14955
uniprot id: D5EHY0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

583355:CAKA RS12450
gene id: 583355:CAKA_RS12450
uniprot id: D5EP12
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS04785
gene id: 583355:CAKA_RS04785
uniprot id: D5ER12
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

583355:CAKA RS03530
gene id: 583355:CAKA_RS03530
uniprot id: D5EPL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

583355:CAKA RS13465
gene id: 583355:CAKA_RS13465
uniprot id: D5EPZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

583355:CAKA RS09320
gene id: 583355:CAKA_RS09320
uniprot id: D5EKE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

583355:CAKA RS10980
gene id: 583355:CAKA_RS10980
uniprot id: D5EM67
names: Similarity
messages: Belongs to the pyruvate kinase family.

583355:CAKA RS11125
gene id: 583355:CAKA_RS11125
uniprot id: D5EM95
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS03165
gene id: 583355:CAKA_RS03165
uniprot id: D5EPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

583355:CAKA RS09730
gene id: 583355:CAKA_RS09730
uniprot id: D5EKR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS15050
gene id: 583355:CAKA_RS15050
uniprot id: D5EI01
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

583355:CAKA RS00985
gene id: 583355:CAKA_RS00985
uniprot id: D5ELR0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

583355:CAKA RS08375
gene id: 583355:CAKA_RS08375
uniprot id: D5EJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

583355:CAKA RS06260
gene id: 583355:CAKA_RS06260
uniprot id: D5EIP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

583355:CAKA RS08335
gene id: 583355:CAKA_RS08335
uniprot id: D5EJV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

583355:CAKA RS07370
gene id: 583355:CAKA_RS07370
uniprot id: D5EJB1
names: Similarity
messages: Belongs to the MYG1 family.

583355:CAKA RS06545
gene id: 583355:CAKA_RS06545
uniprot id: D5EIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

583355:CAKA RS06845
gene id: 583355:CAKA_RS06845
uniprot id: D5EJ08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS12115
gene id: 583355:CAKA_RS12115
uniprot id: D5ENH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

583355:CAKA RS00285
gene id: 583355:CAKA_RS00285
uniprot id: D5EKY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

583355:CAKA RS14900
gene id: 583355:CAKA_RS14900
uniprot id: D5EHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

583355:CAKA RS13450
gene id: 583355:CAKA_RS13450
uniprot id: D5EPY7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

583355:CAKA RS10440
gene id: 583355:CAKA_RS10440
uniprot id: D5ELI5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS14005
gene id: 583355:CAKA_RS14005
uniprot id: D5EQL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

583355:CAKA RS13030
gene id: 583355:CAKA_RS13030
uniprot id: D5EPC8
names: Similarity
messages: Belongs to the OprB family.

583355:CAKA RS04120
gene id: 583355:CAKA_RS04120
uniprot id: D5EQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

583355:CAKA RS01750
gene id: 583355:CAKA_RS01750
uniprot id: D5EMI6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS06275
gene id: 583355:CAKA_RS06275
uniprot id: D5EIP3
names: Similarity
messages: Belongs to the Fur family.

583355:CAKA RS10840
gene id: 583355:CAKA_RS10840
uniprot id: D5EM41
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS00005
gene id: 583355:CAKA_RS00005
uniprot id: D5EKE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

583355:CAKA RS12660
gene id: 583355:CAKA_RS12660
uniprot id: D5EP54
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

583355:CAKA RS14330
gene id: 583355:CAKA_RS14330
uniprot id: D5ER51
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

583355:CAKA RS13005
gene id: 583355:CAKA_RS13005
uniprot id: D5EPC3
names: Similarity
messages: Belongs to the OprB family.

583355:CAKA RS04160
gene id: 583355:CAKA_RS04160
uniprot id: D5EQA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS05780
gene id: 583355:CAKA_RS05780
uniprot id: D5EID8
names: Similarity
messages: Belongs to the peptidase S41A family.

583355:CAKA RS08050
gene id: 583355:CAKA_RS08050
uniprot id: D5EJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

583355:CAKA RS08345
gene id: 583355:CAKA_RS08345
uniprot id: D5EJV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

583355:CAKA RS07100
gene id: 583355:CAKA_RS07100
uniprot id: D5EJ59
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583355:CAKA RS03635
gene id: 583355:CAKA_RS03635
uniprot id: D5EPN5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

583355:CAKA RS13665
gene id: 583355:CAKA_RS13665
uniprot id: D5EQE8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

583355:CAKA RS12010
gene id: 583355:CAKA_RS12010
uniprot id: D5ENF8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS05095
gene id: 583355:CAKA_RS05095
uniprot id: D5EHN0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

583355:CAKA RS07710
gene id: 583355:CAKA_RS07710
uniprot id: D5EJH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS12475
gene id: 583355:CAKA_RS12475
uniprot id: D5EP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

583355:CAKA RS08465
gene id: 583355:CAKA_RS08465
uniprot id: D5EJX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

583355:CAKA RS03450
gene id: 583355:CAKA_RS03450
uniprot id: D5EPJ7
names: Similarity
messages: Belongs to the TlyA family.

583355:CAKA RS11540
gene id: 583355:CAKA_RS11540
uniprot id: D5EMV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

583355:CAKA RS13720
gene id: 583355:CAKA_RS13720
uniprot id: D5EQG0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

583355:CAKA RS02000
gene id: 583355:CAKA_RS02000
uniprot id: D5EN07
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS03670
gene id: 583355:CAKA_RS03670
uniprot id: D5EPP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

583355:CAKA RS12950
gene id: 583355:CAKA_RS12950
uniprot id: D5EPB2
names: Similarity
messages: Belongs to the ArsC family.

583355:CAKA RS10010
gene id: 583355:CAKA_RS10010
uniprot id: D5EL97
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

583355:CAKA RS12800
gene id: 583355:CAKA_RS12800
uniprot id: D5EP82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583355:CAKA RS10585
gene id: 583355:CAKA_RS10585
uniprot id: D5ELL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

583355:CAKA RS08900
gene id: 583355:CAKA_RS08900
uniprot id: D5EK66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

583355:CAKA RS07270
gene id: 583355:CAKA_RS07270
uniprot id: D5EJ92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

583355:CAKA RS00815
gene id: 583355:CAKA_RS00815
uniprot id: D5ELM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS09710
gene id: 583355:CAKA_RS09710
uniprot id: D5EKR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS13765
gene id: 583355:CAKA_RS13765
uniprot id: D5EQG9
names: Similarity
messages: Belongs to the pirin family.

583355:CAKA RS03150
gene id: 583355:CAKA_RS03150
uniprot id: D5EPE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS05320
gene id: 583355:CAKA_RS05320
uniprot id: D5EHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

583355:CAKA RS05835
gene id: 583355:CAKA_RS05835
uniprot id: D5EIE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

583355:CAKA RS03695
gene id: 583355:CAKA_RS03695
uniprot id: D5EPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

583355:CAKA RS10565
gene id: 583355:CAKA_RS10565
uniprot id: D5ELL0
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS10505
gene id: 583355:CAKA_RS10505
uniprot id: D5ELJ8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

583355:CAKA RS02330
gene id: 583355:CAKA_RS02330
uniprot id: D5EN73
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS13455
gene id: 583355:CAKA_RS13455
uniprot id: D5EPY8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

583355:CAKA RS02030
gene id: 583355:CAKA_RS02030
uniprot id: D5EN12
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS01125
gene id: 583355:CAKA_RS01125
uniprot id: D5ELT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS04625
gene id: 583355:CAKA_RS04625
uniprot id: D5EQY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS01835
gene id: 583355:CAKA_RS01835
uniprot id: D5EMK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

583355:CAKA RS04400
gene id: 583355:CAKA_RS04400
uniprot id: D5EQT3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

583355:CAKA RS14480
gene id: 583355:CAKA_RS14480
uniprot id: D5ER81
names: Similarity
messages: Belongs to the cytochrome c-552 family.

583355:CAKA RS08290
gene id: 583355:CAKA_RS08290
uniprot id: D5EJU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

583355:CAKA RS12775
gene id: 583355:CAKA_RS12775
uniprot id: D5EP77
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

583355:CAKA RS13395
gene id: 583355:CAKA_RS13395
uniprot id: D5EPX7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS13290
gene id: 583355:CAKA_RS13290
uniprot id: D5EPV6
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS08680
gene id: 583355:CAKA_RS08680
uniprot id: D5EK22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

583355:CAKA RS10815
gene id: 583355:CAKA_RS10815
uniprot id: D5EM37
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS16315
gene id: 583355:CAKA_RS16315
uniprot id: D5EQ04
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS03520
gene id: 583355:CAKA_RS03520
uniprot id: D5EPL1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

583355:CAKA RS06635
gene id: 583355:CAKA_RS06635
uniprot id: D5EIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

583355:CAKA RS03640
gene id: 583355:CAKA_RS03640
uniprot id: D5EPN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

583355:CAKA RS05475
gene id: 583355:CAKA_RS05475
uniprot id: D5EHV6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

583355:CAKA RS12500
gene id: 583355:CAKA_RS12500
uniprot id: D5EP23
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

583355:CAKA RS03740
gene id: 583355:CAKA_RS03740
uniprot id: D5EPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

583355:CAKA RS08735
gene id: 583355:CAKA_RS08735
uniprot id: D5EK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS15085
gene id: 583355:CAKA_RS15085
uniprot id: D5EI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

583355:CAKA RS02145
gene id: 583355:CAKA_RS02145
uniprot id: D5EN35
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

583355:CAKA RS15120
gene id: 583355:CAKA_RS15120
uniprot id: D5EI15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

583355:CAKA RS01775
gene id: 583355:CAKA_RS01775
uniprot id: D5EMJ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

583355:CAKA RS15095
gene id: 583355:CAKA_RS15095
uniprot id: D5EI10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS11625
gene id: 583355:CAKA_RS11625
uniprot id: D5EMW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

583355:CAKA RS13435
gene id: 583355:CAKA_RS13435
uniprot id: D5EPY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

583355:CAKA RS06835
gene id: 583355:CAKA_RS06835
uniprot id: D5EJ06
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS11900
gene id: 583355:CAKA_RS11900
uniprot id: D5END6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

583355:CAKA RS05630
gene id: 583355:CAKA_RS05630
uniprot id: D5EIA9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

583355:CAKA RS03160
gene id: 583355:CAKA_RS03160
uniprot id: D5EPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS06940
gene id: 583355:CAKA_RS06940
uniprot id: D5EJ27
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

583355:CAKA RS08880
gene id: 583355:CAKA_RS08880
uniprot id: D5EK62
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

583355:CAKA RS09835
gene id: 583355:CAKA_RS09835
uniprot id: D5EKT9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

583355:CAKA RS11055
gene id: 583355:CAKA_RS11055
uniprot id: D5EM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583355:CAKA RS14870
gene id: 583355:CAKA_RS14870
uniprot id: D5ERG0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

583355:CAKA RS08675
gene id: 583355:CAKA_RS08675
uniprot id: D5EK21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

583355:CAKA RS08250
gene id: 583355:CAKA_RS08250
uniprot id: D5EJT5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

583355:CAKA RS01995
gene id: 583355:CAKA_RS01995
uniprot id: D5EN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

583355:CAKA RS14690
gene id: 583355:CAKA_RS14690
uniprot id: D5ERC2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

583355:CAKA RS12430
gene id: 583355:CAKA_RS12430
uniprot id: D5ENP1
names: Similarity
messages: Belongs to the SufE family.

583355:CAKA RS06420
gene id: 583355:CAKA_RS06420
uniprot id: D5EIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS09130
gene id: 583355:CAKA_RS09130
uniprot id: D5EKA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

583355:CAKA RS07560
gene id: 583355:CAKA_RS07560
uniprot id: D5EJE8
names: Similarity
messages: Belongs to the CFA/CMAS family.

583355:CAKA RS07630
gene id: 583355:CAKA_RS07630
uniprot id: D5EJG1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS14915
gene id: 583355:CAKA_RS14915
uniprot id: D5EHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

583355:CAKA RS13595
gene id: 583355:CAKA_RS13595
uniprot id: D5EQ17
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS12045
gene id: 583355:CAKA_RS12045
uniprot id: D5ENG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS10905
gene id: 583355:CAKA_RS10905
uniprot id: D5EM52
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS12395
gene id: 583355:CAKA_RS12395
uniprot id: D5ENN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

583355:CAKA RS05435
gene id: 583355:CAKA_RS05435
uniprot id: D5EHU8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

583355:CAKA RS05620
gene id: 583355:CAKA_RS05620
uniprot id: D5EIA7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

583355:CAKA RS13650
gene id: 583355:CAKA_RS13650
uniprot id: D5EQ26
names: Similarity
messages: Belongs to the glutamine synthetase family.

583355:CAKA RS11340
gene id: 583355:CAKA_RS11340
uniprot id: D5EMR0
names: Similarity
messages: Belongs to the AIR synthase family.

583355:CAKA RS05305
gene id: 583355:CAKA_RS05305
uniprot id: D5EHS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

583355:CAKA RS08325
gene id: 583355:CAKA_RS08325
uniprot id: D5EJV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

583355:CAKA RS12735
gene id: 583355:CAKA_RS12735
uniprot id: D5EP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS09010
gene id: 583355:CAKA_RS09010
uniprot id: D5EK83
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

583355:CAKA RS02100
gene id: 583355:CAKA_RS02100
uniprot id: D5EN26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

583355:CAKA RS11110
gene id: 583355:CAKA_RS11110
uniprot id: D5EM92
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

583355:CAKA RS13875
gene id: 583355:CAKA_RS13875
uniprot id: D5EQI9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583355:CAKA RS02045
gene id: 583355:CAKA_RS02045
uniprot id: D5EN15
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS07975
gene id: 583355:CAKA_RS07975
uniprot id: D5EJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

583355:CAKA RS12835
gene id: 583355:CAKA_RS12835
uniprot id: D5EP89
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583355:CAKA RS12355
gene id: 583355:CAKA_RS12355
uniprot id: D5ENM6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

583355:CAKA RS14695
gene id: 583355:CAKA_RS14695
uniprot id: D5ERC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS00035
gene id: 583355:CAKA_RS00035
uniprot id: D5EKF5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

583355:CAKA RS02110
gene id: 583355:CAKA_RS02110
uniprot id: D5EN28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

583355:CAKA RS12305
gene id: 583355:CAKA_RS12305
uniprot id: D5ENL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

583355:CAKA RS08255
gene id: 583355:CAKA_RS08255
uniprot id: D5EJT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

583355:CAKA RS05940
gene id: 583355:CAKA_RS05940
uniprot id: D5EIG9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

583355:CAKA RS14910
gene id: 583355:CAKA_RS14910
uniprot id: D5EHX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

583355:CAKA RS04240
gene id: 583355:CAKA_RS04240
uniprot id: D5EQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

583355:CAKA RS00550
gene id: 583355:CAKA_RS00550
uniprot id: D5EL41
names: Subcellular Location Annotation
messages: Cytoplasm

583355:CAKA RS11715
gene id: 583355:CAKA_RS11715
uniprot id: D5EMY6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

583355:CAKA RS00095
gene id: 583355:CAKA_RS00095
uniprot id: D5EKG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

583355:CAKA RS01755
gene id: 583355:CAKA_RS01755
uniprot id: D5EMI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

583355:CAKA RS12365
gene id: 583355:CAKA_RS12365
uniprot id: D5ENM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

583355:CAKA RS14975
gene id: 583355:CAKA_RS14975
uniprot id: D5EHY5
names: Similarity
messages: Belongs to the DEAD box helicase family.

583355:CAKA RS07350
gene id: 583355:CAKA_RS07350
uniprot id: D5EJA6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

583355:CAKA RS04430
gene id: 583355:CAKA_RS04430
uniprot id: D5EQT9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583355:CAKA RS08540
gene id: 583355:CAKA_RS08540
uniprot id: D5EJZ3
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07760
gene id: 583355:CAKA_RS07760
uniprot id: D5EJI7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

583355:CAKA RS11355
gene id: 583355:CAKA_RS11355
uniprot id: D5EMR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583355:CAKA RS11525
gene id: 583355:CAKA_RS11525
uniprot id: D5EMU7
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS12110
gene id: 583355:CAKA_RS12110
uniprot id: D5ENH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

583355:CAKA RS07005
gene id: 583355:CAKA_RS07005
uniprot id: D5EJ40
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

583355:CAKA RS14645
gene id: 583355:CAKA_RS14645
uniprot id: D5ERB3
names: Similarity
messages: Belongs to the bacterial secretin family.

583355:CAKA RS07605
gene id: 583355:CAKA_RS07605
uniprot id: D5EJF7
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS10380
gene id: 583355:CAKA_RS10380
uniprot id: D5ELH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS13760
gene id: 583355:CAKA_RS13760
uniprot id: D5EQG8
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS06665
gene id: 583355:CAKA_RS06665
uniprot id: D5EIX0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583355:CAKA RS14820
gene id: 583355:CAKA_RS14820
uniprot id: D5ERF0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

583355:CAKA RS14785
gene id: 583355:CAKA_RS14785
uniprot id: D5ERE3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

583355:CAKA RS09210
gene id: 583355:CAKA_RS09210
uniprot id: D5EKC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

583355:CAKA RS07475
gene id: 583355:CAKA_RS07475
uniprot id: D5EJD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

583355:CAKA RS05220
gene id: 583355:CAKA_RS05220
uniprot id: D5EHQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

583355:CAKA RS02490
gene id: 583355:CAKA_RS02490
uniprot id: D5ENA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

583355:CAKA RS01265
gene id: 583355:CAKA_RS01265
uniprot id: D5ELW9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

583355:CAKA RS11965
gene id: 583355:CAKA_RS11965
uniprot id: D5ENE9
names: Similarity
messages: Belongs to the SurE nucleotidase family.

583355:CAKA RS12830
gene id: 583355:CAKA_RS12830
uniprot id: D5EP88
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583355:CAKA RS10480
gene id: 583355:CAKA_RS10480
uniprot id: D5ELJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

583355:CAKA RS05930
gene id: 583355:CAKA_RS05930
uniprot id: D5EIG7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

583355:CAKA RS11465
gene id: 583355:CAKA_RS11465
uniprot id: D5EMT5
names: Similarity
messages: Belongs to the CinA family.

583355:CAKA RS04440
gene id: 583355:CAKA_RS04440
uniprot id: D5EQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

583355:CAKA RS09810
gene id: 583355:CAKA_RS09810
uniprot id: D5EKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

583355:CAKA RS13985
gene id: 583355:CAKA_RS13985
uniprot id: D5EQL1
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

583355:CAKA RS00360
gene id: 583355:CAKA_RS00360
uniprot id: D5EL01
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

583355:CAKA RS06820
gene id: 583355:CAKA_RS06820
uniprot id: D5EJ03
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS02930
gene id: 583355:CAKA_RS02930
uniprot id: D5ENX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

583355:CAKA RS12350
gene id: 583355:CAKA_RS12350
uniprot id: D5ENM5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

583355:CAKA RS11325
gene id: 583355:CAKA_RS11325
uniprot id: D5EMQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

583355:CAKA RS04740
gene id: 583355:CAKA_RS04740
uniprot id: D5ER03
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

583355:CAKA RS06725
gene id: 583355:CAKA_RS06725
uniprot id: D5EIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583355:CAKA RS12445
gene id: 583355:CAKA_RS12445
uniprot id: D5EP11
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

583355:CAKA RS11195
gene id: 583355:CAKA_RS11195
uniprot id: D5EMA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

583355:CAKA RS13270
gene id: 583355:CAKA_RS13270
uniprot id: D5EPV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

583355:CAKA RS11235
gene id: 583355:CAKA_RS11235
uniprot id: D5EMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583355:CAKA RS04355
gene id: 583355:CAKA_RS04355
uniprot id: D5EQS2
names: Similarity
messages: Belongs to the cytochrome P450 family.

583355:CAKA RS05905
gene id: 583355:CAKA_RS05905
uniprot id: D5EIG2
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

583355:CAKA RS07585
gene id: 583355:CAKA_RS07585
uniprot id: D5EJF3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

583355:CAKA RS00040
gene id: 583355:CAKA_RS00040
uniprot id: D5EKF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS00735
gene id: 583355:CAKA_RS00735
uniprot id: D5EL82
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583355:CAKA RS14810
gene id: 583355:CAKA_RS14810
uniprot id: D5ERE8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

583355:CAKA RS14760
gene id: 583355:CAKA_RS14760
uniprot id: D5ERD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583355:CAKA RS06950
gene id: 583355:CAKA_RS06950
uniprot id: D5EJ29
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

583355:CAKA RS15445
gene id: 583355:CAKA_RS15445
uniprot id: D5EI87
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583355:CAKA RS13305
gene id: 583355:CAKA_RS13305
uniprot id: D5EPV9
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS08775
gene id: 583355:CAKA_RS08775
uniprot id: D5EK41
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

583355:CAKA RS00465
gene id: 583355:CAKA_RS00465
uniprot id: D5EL24
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

583355:CAKA RS10365
gene id: 583355:CAKA_RS10365
uniprot id: D5ELH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS15040
gene id: 583355:CAKA_RS15040
uniprot id: D5EHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

583355:CAKA RS02085
gene id: 583355:CAKA_RS02085
uniprot id: D5EN23
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

583355:CAKA RS09120
gene id: 583355:CAKA_RS09120
uniprot id: D5EKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

583355:CAKA RS09165
gene id: 583355:CAKA_RS09165
uniprot id: D5EKB5
names: Similarity
messages: Belongs to the peptidase S1C family.

583355:CAKA RS08275
gene id: 583355:CAKA_RS08275
uniprot id: D5EJU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

583355:CAKA RS02055
gene id: 583355:CAKA_RS02055
uniprot id: D5EN17
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS03555
gene id: 583355:CAKA_RS03555
uniprot id: D5EPL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS14090
gene id: 583355:CAKA_RS14090
uniprot id: D5EQN3
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

583355:CAKA RS11895
gene id: 583355:CAKA_RS11895
uniprot id: D5END5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

583355:CAKA RS16985
gene id: 583355:CAKA_RS16985
uniprot id: D5EM00
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

583355:CAKA RS14680
gene id: 583355:CAKA_RS14680
uniprot id: D5ERC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

583355:CAKA RS10210
gene id: 583355:CAKA_RS10210
uniprot id: D5ELD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

583355:CAKA RS00990
gene id: 583355:CAKA_RS00990
uniprot id: D5ELR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS10700
gene id: 583355:CAKA_RS10700
uniprot id: D5EM14
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

583355:CAKA RS12980
gene id: 583355:CAKA_RS12980
uniprot id: D5EPB8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

583355:CAKA RS01890
gene id: 583355:CAKA_RS01890
uniprot id: D5EML4
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS11915
gene id: 583355:CAKA_RS11915
uniprot id: D5END9
names: Subcellular Location Annotation
messages: Nucleus

583355:CAKA RS11485
gene id: 583355:CAKA_RS11485
uniprot id: D5EMT9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

583355:CAKA RS12435
gene id: 583355:CAKA_RS12435
uniprot id: D5ENP3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

583355:CAKA RS07935
gene id: 583355:CAKA_RS07935
uniprot id: D5EJM3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

583355:CAKA RS06505
gene id: 583355:CAKA_RS06505
uniprot id: D5EIT8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

583355:CAKA RS01095
gene id: 583355:CAKA_RS01095
uniprot id: D5ELT2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS05735
gene id: 583355:CAKA_RS05735
uniprot id: D5EIC9
names: Similarity
messages: Belongs to the HsdR family.

583355:CAKA RS14755
gene id: 583355:CAKA_RS14755
uniprot id: D5ERD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS05925
gene id: 583355:CAKA_RS05925
uniprot id: D5EIG6
names: Similarity
messages: Belongs to the Fur family.

583355:CAKA RS10220
gene id: 583355:CAKA_RS10220
uniprot id: D5ELD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS12880
gene id: 583355:CAKA_RS12880
uniprot id: D5EP98
names: Similarity
messages: Belongs to the peptidase M24B family.

583355:CAKA RS02065
gene id: 583355:CAKA_RS02065
uniprot id: D5EN19
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS13555
gene id: 583355:CAKA_RS13555
uniprot id: D5EQ09
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

583355:CAKA RS05980
gene id: 583355:CAKA_RS05980
uniprot id: D5EIH7
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS12915
gene id: 583355:CAKA_RS12915
uniprot id: D5EPA5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583355:CAKA RS14735
gene id: 583355:CAKA_RS14735
uniprot id: D5ERD2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

583355:CAKA RS10075
gene id: 583355:CAKA_RS10075
uniprot id: D5ELB0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

583355:CAKA RS03980
gene id: 583355:CAKA_RS03980
uniprot id: D5EQ72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

583355:CAKA RS00775
gene id: 583355:CAKA_RS00775
uniprot id: D5EL89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

583355:CAKA RS06510
gene id: 583355:CAKA_RS06510
uniprot id: D5EIT9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

583355:CAKA RS08155
gene id: 583355:CAKA_RS08155
uniprot id: D5EJR7
names: Similarity
messages: Belongs to the NDK family.

583355:CAKA RS06335
gene id: 583355:CAKA_RS06335
uniprot id: D5EIQ5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

583355:CAKA RS12165
gene id: 583355:CAKA_RS12165
uniprot id: D5ENI9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

583355:CAKA RS07460
gene id: 583355:CAKA_RS07460
uniprot id: D5EJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583355:CAKA RS06920
gene id: 583355:CAKA_RS06920
uniprot id: D5EJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

583355:CAKA RS12760
gene id: 583355:CAKA_RS12760
uniprot id: D5EP74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583355:CAKA RS12415
gene id: 583355:CAKA_RS12415
uniprot id: D5ENN8
names: Similarity
messages: Belongs to the MlaA family.

583355:CAKA RS12795
gene id: 583355:CAKA_RS12795
uniprot id: D5EP81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

583355:CAKA RS10790
gene id: 583355:CAKA_RS10790
uniprot id: D5EM32
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

583355:CAKA RS08670
gene id: 583355:CAKA_RS08670
uniprot id: D5EK20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

583355:CAKA RS09300
gene id: 583355:CAKA_RS09300
uniprot id: D5EKE2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

583355:CAKA RS10080
gene id: 583355:CAKA_RS10080
uniprot id: D5ELB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583355:CAKA RS13770
gene id: 583355:CAKA_RS13770
uniprot id: D5EQH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS11815
gene id: 583355:CAKA_RS11815
uniprot id: D5ENB9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

583355:CAKA RS09470
gene id: 583355:CAKA_RS09470
uniprot id: D5EKL7
names: Similarity
messages: Belongs to the DNA photolyase family.

583355:CAKA RS08355
gene id: 583355:CAKA_RS08355
uniprot id: D5EJV6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

583355:CAKA RS14225
gene id: 583355:CAKA_RS14225
uniprot id: D5EQQ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583355:CAKA RS07050
gene id: 583355:CAKA_RS07050
uniprot id: D5EJ49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

583355:CAKA RS05675
gene id: 583355:CAKA_RS05675
uniprot id: D5EIB8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

583355:CAKA RS11950
gene id: 583355:CAKA_RS11950
uniprot id: D5ENE6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

583355:CAKA RS04050
gene id: 583355:CAKA_RS04050
uniprot id: D5EQ86
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

583355:CAKA RS08095
gene id: 583355:CAKA_RS08095
uniprot id: D5EJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

583355:CAKA RS01640
gene id: 583355:CAKA_RS01640
uniprot id: D5EMG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583355:CAKA RS09220
gene id: 583355:CAKA_RS09220
uniprot id: D5EKC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

583355:CAKA RS12000
gene id: 583355:CAKA_RS12000
uniprot id: D5ENF6
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS00750
gene id: 583355:CAKA_RS00750
uniprot id: D5EL84
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583355:CAKA RS14100
gene id: 583355:CAKA_RS14100
uniprot id: D5EQN5
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

583355:CAKA RS13745
gene id: 583355:CAKA_RS13745
uniprot id: D5EQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS01170
gene id: 583355:CAKA_RS01170
uniprot id: D5ELU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

583355:CAKA RS07230
gene id: 583355:CAKA_RS07230
uniprot id: D5EJ83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

583355:CAKA RS01255
gene id: 583355:CAKA_RS01255
uniprot id: D5ELW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

583355:CAKA RS14965
gene id: 583355:CAKA_RS14965
uniprot id: D5EHY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

583355:CAKA RS13905
gene id: 583355:CAKA_RS13905
uniprot id: D5EQJ5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

583355:CAKA RS05110
gene id: 583355:CAKA_RS05110
uniprot id: D5EHN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

583355:CAKA RS11870
gene id: 583355:CAKA_RS11870
uniprot id: D5END0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS01310
gene id: 583355:CAKA_RS01310
uniprot id: D5ELX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS15895
gene id: 583355:CAKA_RS15895
uniprot id: D5EHW5
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07150
gene id: 583355:CAKA_RS07150
uniprot id: D5EJ68
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS06830
gene id: 583355:CAKA_RS06830
uniprot id: D5EJ05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS14105
gene id: 583355:CAKA_RS14105
uniprot id: D5EQN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

583355:CAKA RS02220
gene id: 583355:CAKA_RS02220
uniprot id: D5EN51
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS12195
gene id: 583355:CAKA_RS12195
uniprot id: D5ENJ5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

583355:CAKA RS11860
gene id: 583355:CAKA_RS11860
uniprot id: D5ENC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

583355:CAKA RS12510
gene id: 583355:CAKA_RS12510
uniprot id: D5EP25
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

583355:CAKA RS12825
gene id: 583355:CAKA_RS12825
uniprot id: D5EP87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583355:CAKA RS15240
gene id: 583355:CAKA_RS15240
uniprot id: D5EI41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

583355:CAKA RS13075
gene id: 583355:CAKA_RS13075
uniprot id: D5EPR5
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS10775
gene id: 583355:CAKA_RS10775
uniprot id: D5EM29
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

583355:CAKA RS03875
gene id: 583355:CAKA_RS03875
uniprot id: D5EQ51
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

583355:CAKA RS12910
gene id: 583355:CAKA_RS12910
uniprot id: D5EPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

583355:CAKA RS07565
gene id: 583355:CAKA_RS07565
uniprot id: D5EJE9
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS08985
gene id: 583355:CAKA_RS08985
uniprot id: D5EK78
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

583355:CAKA RS12930
gene id: 583355:CAKA_RS12930
uniprot id: D5EPA8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

583355:CAKA RS07365
gene id: 583355:CAKA_RS07365
uniprot id: D5EJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

583355:CAKA RS08995
gene id: 583355:CAKA_RS08995
uniprot id: D5EK80
names: Subunit
messages: Homodimer.

583355:CAKA RS11925
gene id: 583355:CAKA_RS11925
uniprot id: D5ENE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS12140
gene id: 583355:CAKA_RS12140
uniprot id: D5ENI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583355:CAKA RS10240
gene id: 583355:CAKA_RS10240
uniprot id: D5ELE3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

583355:CAKA RS11920
gene id: 583355:CAKA_RS11920
uniprot id: D5ENE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

583355:CAKA RS07055
gene id: 583355:CAKA_RS07055
uniprot id: D5EJ50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

583355:CAKA RS02050
gene id: 583355:CAKA_RS02050
uniprot id: D5EN16
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS00050
gene id: 583355:CAKA_RS00050
uniprot id: D5EKF8
names: Similarity
messages: Belongs to the ArsC family.

583355:CAKA RS11350
gene id: 583355:CAKA_RS11350
uniprot id: D5EMR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

583355:CAKA RS12750
gene id: 583355:CAKA_RS12750
uniprot id: D5EP72
names: Similarity
messages: Belongs to the P(II) protein family.

583355:CAKA RS14905
gene id: 583355:CAKA_RS14905
uniprot id: D5EHX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS11680
gene id: 583355:CAKA_RS11680
uniprot id: D5EMX9
names: Similarity
messages: Belongs to the LOG family.

583355:CAKA RS02180
gene id: 583355:CAKA_RS02180
uniprot id: D5EN43
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS02910
gene id: 583355:CAKA_RS02910
uniprot id: D5ENX1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS07910
gene id: 583355:CAKA_RS07910
uniprot id: D5EJL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS01980
gene id: 583355:CAKA_RS01980
uniprot id: D5EMN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583355:CAKA RS03000
gene id: 583355:CAKA_RS03000
uniprot id: D5ENY9
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

583355:CAKA RS05090
gene id: 583355:CAKA_RS05090
uniprot id: D5EHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

583355:CAKA RS07985
gene id: 583355:CAKA_RS07985
uniprot id: D5EJN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

583355:CAKA RS08905
gene id: 583355:CAKA_RS08905
uniprot id: D5EK67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS15235
gene id: 583355:CAKA_RS15235
uniprot id: D5EI40
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

583355:CAKA RS11560
gene id: 583355:CAKA_RS11560
uniprot id: D5EMV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS09965
gene id: 583355:CAKA_RS09965
uniprot id: D5EKW6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

583355:CAKA RS14300
gene id: 583355:CAKA_RS14300
uniprot id: D5ER45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583355:CAKA RS16205
gene id: 583355:CAKA_RS16205
uniprot id: D5EMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583355:CAKA RS08625
gene id: 583355:CAKA_RS08625
uniprot id: D5EK11
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS04135
gene id: 583355:CAKA_RS04135
uniprot id: D5EQA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

583355:CAKA RS12555
gene id: 583355:CAKA_RS12555
uniprot id: D5EP34
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

583355:CAKA RS06520
gene id: 583355:CAKA_RS06520
uniprot id: D5EIU1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

583355:CAKA RS05785
gene id: 583355:CAKA_RS05785
uniprot id: D5EID9
names: Subcellular Location Annotation
messages: Mitochondrion

583355:CAKA RS09040
gene id: 583355:CAKA_RS09040
uniprot id: D5EK89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

583355:CAKA RS01605
gene id: 583355:CAKA_RS01605
uniprot id: D5EMF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

583355:CAKA RS08470
gene id: 583355:CAKA_RS08470
uniprot id: D5EJX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

583355:CAKA RS01185
gene id: 583355:CAKA_RS01185
uniprot id: D5ELV2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

583355:CAKA RS13400
gene id: 583355:CAKA_RS13400
uniprot id: D5EPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

583355:CAKA RS05160
gene id: 583355:CAKA_RS05160
uniprot id: D5EHP4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

583355:CAKA RS13420
gene id: 583355:CAKA_RS13420
uniprot id: D5EPY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

583355:CAKA RS05510
gene id: 583355:CAKA_RS05510
uniprot id: D5EHW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

583355:CAKA RS08305
gene id: 583355:CAKA_RS08305
uniprot id: D5EJU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

583355:CAKA RS13475
gene id: 583355:CAKA_RS13475
uniprot id: D5EPZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583355:CAKA RS14715
gene id: 583355:CAKA_RS14715
uniprot id: D5ERC8
names: Similarity
messages: Belongs to the TrpF family.

583355:CAKA RS09090
gene id: 583355:CAKA_RS09090
uniprot id: D5EK99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

583355:CAKA RS10460
gene id: 583355:CAKA_RS10460
uniprot id: D5ELI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

583355:CAKA RS08975
gene id: 583355:CAKA_RS08975
uniprot id: D5EK76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

583355:CAKA RS10675
gene id: 583355:CAKA_RS10675
uniprot id: D5EM09
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS09105
gene id: 583355:CAKA_RS09105
uniprot id: D5EKA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

583355:CAKA RS01110
gene id: 583355:CAKA_RS01110
uniprot id: D5ELT5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS10320
gene id: 583355:CAKA_RS10320
uniprot id: D5ELG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcriptional regulator.

583355:CAKA RS02450
gene id: 583355:CAKA_RS02450
uniprot id: D5EN97
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

583355:CAKA RS08895
gene id: 583355:CAKA_RS08895
uniprot id: D5EK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

583355:CAKA RS09755
gene id: 583355:CAKA_RS09755
uniprot id: D5EKS4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

583355:CAKA RS03940
gene id: 583355:CAKA_RS03940
uniprot id: D5EQ64
names: Similarity
messages: Belongs to the aldose epimerase family.

583355:CAKA RS14565
gene id: 583355:CAKA_RS14565
uniprot id: D5ER98
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

583355:CAKA RS05540
gene id: 583355:CAKA_RS05540
uniprot id: D5EI93
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

583355:CAKA RS06600
gene id: 583355:CAKA_RS06600
uniprot id: D5EIV7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

583355:CAKA RS02210
gene id: 583355:CAKA_RS02210
uniprot id: D5EN49
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

583355:CAKA RS09795
gene id: 583355:CAKA_RS09795
uniprot id: D5EKT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS08455
gene id: 583355:CAKA_RS08455
uniprot id: D5EJX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

583355:CAKA RS06755
gene id: 583355:CAKA_RS06755
uniprot id: D5EIY8
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

583355:CAKA RS06815
gene id: 583355:CAKA_RS06815
uniprot id: D5EJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS00755
gene id: 583355:CAKA_RS00755
uniprot id: D5EL85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

583355:CAKA RS04295
gene id: 583355:CAKA_RS04295
uniprot id: D5EQD4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS13970
gene id: 583355:CAKA_RS13970
uniprot id: D5EQK8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

583355:CAKA RS11105
gene id: 583355:CAKA_RS11105
uniprot id: D5EM91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

583355:CAKA RS01845
gene id: 583355:CAKA_RS01845
uniprot id: D5EMK5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

583355:CAKA RS10485
gene id: 583355:CAKA_RS10485
uniprot id: D5ELJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

583355:CAKA RS02020
gene id: 583355:CAKA_RS02020
uniprot id: D5EN10
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

583355:CAKA RS10385
gene id: 583355:CAKA_RS10385
uniprot id: D5ELH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

583355:CAKA RS15130
gene id: 583355:CAKA_RS15130
uniprot id: D5EI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583355:CAKA RS10455
gene id: 583355:CAKA_RS10455
uniprot id: D5ELI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

583355:CAKA RS05105
gene id: 583355:CAKA_RS05105
uniprot id: D5EHN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

583355:CAKA RS00980
gene id: 583355:CAKA_RS00980
uniprot id: D5ELQ9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

583355:CAKA RS04645
gene id: 583355:CAKA_RS04645
uniprot id: D5EQY5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

583355:CAKA RS06945
gene id: 583355:CAKA_RS06945
uniprot id: D5EJ28
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

583355:CAKA RS15555
gene id: 583355:CAKA_RS15555
uniprot id: D5EIM8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

583355:CAKA RS08170
gene id: 583355:CAKA_RS08170
uniprot id: D5EJS0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583355:CAKA RS11095
gene id: 583355:CAKA_RS11095
uniprot id: D5EM89
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583355:CAKA RS09005
gene id: 583355:CAKA_RS09005
uniprot id: D5EK82
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

583355:CAKA RS14125
gene id: 583355:CAKA_RS14125
uniprot id: D5EQP0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

583355:CAKA RS01120
gene id: 583355:CAKA_RS01120
uniprot id: D5ELT8
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS12080
gene id: 583355:CAKA_RS12080
uniprot id: D5ENH2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

583355:CAKA RS16195
gene id: 583355:CAKA_RS16195
uniprot id: D5EMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

583355:CAKA RS05820
gene id: 583355:CAKA_RS05820
uniprot id: D5EIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

583355:CAKA RS08685
gene id: 583355:CAKA_RS08685
uniprot id: D5EK23
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583355:CAKA RS13795
gene id: 583355:CAKA_RS13795
uniprot id: D5EQH3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS13955
gene id: 583355:CAKA_RS13955
uniprot id: D5EQK5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

583355:CAKA RS01280
gene id: 583355:CAKA_RS01280
uniprot id: D5ELX2
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS12740
gene id: 583355:CAKA_RS12740
uniprot id: D5EP69
names: Similarity
messages: Belongs to the P(II) protein family.

583355:CAKA RS09185
gene id: 583355:CAKA_RS09185
uniprot id: D5EKB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

583355:CAKA RS03370
gene id: 583355:CAKA_RS03370
uniprot id: D5EPI0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

583355:CAKA RS07165
gene id: 583355:CAKA_RS07165
uniprot id: D5EJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

583355:CAKA RS09410
gene id: 583355:CAKA_RS09410
uniprot id: D5EKK5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

583355:CAKA RS13175
gene id: 583355:CAKA_RS13175
uniprot id: D5EPT4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

583355:CAKA RS10990
gene id: 583355:CAKA_RS10990
uniprot id: D5EM69
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

583355:CAKA RS01005
gene id: 583355:CAKA_RS01005
uniprot id: D5ELR4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

583355:CAKA RS11275
gene id: 583355:CAKA_RS11275
uniprot id: D5EMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS00305
gene id: 583355:CAKA_RS00305
uniprot id: D5EKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

583355:CAKA RS07335
gene id: 583355:CAKA_RS07335
uniprot id: D5EJA3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

583355:CAKA RS05815
gene id: 583355:CAKA_RS05815
uniprot id: D5EIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

583355:CAKA RS09715
gene id: 583355:CAKA_RS09715
uniprot id: D5EKR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

583355:CAKA RS11985
gene id: 583355:CAKA_RS11985
uniprot id: D5ENF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

583355:CAKA RS12865
gene id: 583355:CAKA_RS12865
uniprot id: D5EP95
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583355:CAKA RS00195
gene id: 583355:CAKA_RS00195
uniprot id: D5EKI8
names: Similarity
messages: Belongs to the DEAD box helicase family.

583355:CAKA RS00745
gene id: 583355:CAKA_RS00745
uniprot id: D5EL83
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583355:CAKA RS02435
gene id: 583355:CAKA_RS02435
uniprot id: D5EN94
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS05375
gene id: 583355:CAKA_RS05375
uniprot id: D5EHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

583355:CAKA RS02895
gene id: 583355:CAKA_RS02895
uniprot id: D5ENW8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS15540
gene id: 583355:CAKA_RS15540
uniprot id: D5EIM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS10410
gene id: 583355:CAKA_RS10410
uniprot id: D5ELH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

583355:CAKA RS03820
gene id: 583355:CAKA_RS03820
uniprot id: D5EQ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

583355:CAKA RS13460
gene id: 583355:CAKA_RS13460
uniprot id: D5EPY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

583355:CAKA RS06870
gene id: 583355:CAKA_RS06870
uniprot id: D5EJ13
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

583355:CAKA RS03495
gene id: 583355:CAKA_RS03495
uniprot id: D5EPK6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

583355:CAKA RS05455
gene id: 583355:CAKA_RS05455
uniprot id: D5EHV2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

583355:CAKA RS10040
gene id: 583355:CAKA_RS10040
uniprot id: D5ELA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

583355:CAKA RS08330
gene id: 583355:CAKA_RS08330
uniprot id: D5EJV1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

583355:CAKA RS11025
gene id: 583355:CAKA_RS11025
uniprot id: D5EM76
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

583355:CAKA RS11670
gene id: 583355:CAKA_RS11670
uniprot id: D5EMX7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

583355:CAKA RS14085
gene id: 583355:CAKA_RS14085
uniprot id: D5EQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

583355:CAKA RS04665
gene id: 583355:CAKA_RS04665
uniprot id: D5EQY9
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

583355:CAKA RS04175
gene id: 583355:CAKA_RS04175
uniprot id: D5EQA9
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS02920
gene id: 583355:CAKA_RS02920
uniprot id: D5ENX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

583355:CAKA RS08225
gene id: 583355:CAKA_RS08225
uniprot id: D5EJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS06530
gene id: 583355:CAKA_RS06530
uniprot id: D5EIU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

583355:CAKA RS13265
gene id: 583355:CAKA_RS13265
uniprot id: D5EPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

583355:CAKA RS01235
gene id: 583355:CAKA_RS01235
uniprot id: D5ELW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS02185
gene id: 583355:CAKA_RS02185
uniprot id: D5EN44
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

583355:CAKA RS07860
gene id: 583355:CAKA_RS07860
uniprot id: D5EJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

583355:CAKA RS05395
gene id: 583355:CAKA_RS05395
uniprot id: D5EHU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

583355:CAKA RS12385
gene id: 583355:CAKA_RS12385
uniprot id: D5ENN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

583355:CAKA RS14230
gene id: 583355:CAKA_RS14230
uniprot id: D5EQQ9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

583355:CAKA RS01735
gene id: 583355:CAKA_RS01735
uniprot id: D5EMI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

583355:CAKA RS06400
gene id: 583355:CAKA_RS06400
uniprot id: D5EIR8
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS01985
gene id: 583355:CAKA_RS01985
uniprot id: D5EN04
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

583355:CAKA RS16795
gene id: 583355:CAKA_RS16795
uniprot id: D5ELN2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583355:CAKA RS05325
gene id: 583355:CAKA_RS05325
uniprot id: D5EHS6
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

583355:CAKA RS02905
gene id: 583355:CAKA_RS02905
uniprot id: D5ENX0
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS01155
gene id: 583355:CAKA_RS01155
uniprot id: D5ELU6
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS10190
gene id: 583355:CAKA_RS10190
uniprot id: D5ELD3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

583355:CAKA RS03310
gene id: 583355:CAKA_RS03310
uniprot id: D5EPH0
names: Subcellular Location Annotation
messages: Secreted

583355:CAKA RS13675
gene id: 583355:CAKA_RS13675
uniprot id: D5EQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS03570
gene id: 583355:CAKA_RS03570
uniprot id: D5EPM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

583355:CAKA RS03990
gene id: 583355:CAKA_RS03990
uniprot id: D5EQ74
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS08295
gene id: 583355:CAKA_RS08295
uniprot id: D5EJU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

583355:CAKA RS03575
gene id: 583355:CAKA_RS03575
uniprot id: D5EPM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

583355:CAKA RS09255
gene id: 583355:CAKA_RS09255
uniprot id: D5EKD3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

583355:CAKA RS08210
gene id: 583355:CAKA_RS08210
uniprot id: D5EJS7
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07915
gene id: 583355:CAKA_RS07915
uniprot id: D5EJL9
names: Similarity
messages: Belongs to the CutA family.

583355:CAKA RS09095
gene id: 583355:CAKA_RS09095
uniprot id: D5EKA0
names: Similarity
messages: Belongs to the DprA/Smf family.

583355:CAKA RS08230
gene id: 583355:CAKA_RS08230
uniprot id: D5EJT1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

583355:CAKA RS02565
gene id: 583355:CAKA_RS02565
uniprot id: D5ENP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

583355:CAKA RS00680
gene id: 583355:CAKA_RS00680
uniprot id: D5EL70
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS09085
gene id: 583355:CAKA_RS09085
uniprot id: D5EK98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

583355:CAKA RS09480
gene id: 583355:CAKA_RS09480
uniprot id: D5EKL9
names: Similarity
messages: Belongs to the UDPGP type 1 family.

583355:CAKA RS03245
gene id: 583355:CAKA_RS03245
uniprot id: D5EPF9
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

583355:CAKA RS13920
gene id: 583355:CAKA_RS13920
uniprot id: D5EQJ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583355:CAKA RS04425
gene id: 583355:CAKA_RS04425
uniprot id: D5EQT8
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07000
gene id: 583355:CAKA_RS07000
uniprot id: D5EJ39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

583355:CAKA RS06555
gene id: 583355:CAKA_RS06555
uniprot id: D5EIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS06285
gene id: 583355:CAKA_RS06285
uniprot id: D5EIP5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

583355:CAKA RS16885
gene id: 583355:CAKA_RS16885
uniprot id: D5EMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

583355:CAKA RS06970
gene id: 583355:CAKA_RS06970
uniprot id: D5EJ33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583355:CAKA RS14165
gene id: 583355:CAKA_RS14165
uniprot id: D5EQP8
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS03255
gene id: 583355:CAKA_RS03255
uniprot id: D5EPG1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

583355:CAKA RS12960
gene id: 583355:CAKA_RS12960
uniprot id: D5EPB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

583355:CAKA RS11080
gene id: 583355:CAKA_RS11080
uniprot id: D5EM86
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

583355:CAKA RS14795
gene id: 583355:CAKA_RS14795
uniprot id: D5ERE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

583355:CAKA RS07570
gene id: 583355:CAKA_RS07570
uniprot id: D5EJF0
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS04600
gene id: 583355:CAKA_RS04600
uniprot id: D5EQX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

583355:CAKA RS04505
gene id: 583355:CAKA_RS04505
uniprot id: D5EQV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

583355:CAKA RS08265
gene id: 583355:CAKA_RS08265
uniprot id: D5EJT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

583355:CAKA RS08750
gene id: 583355:CAKA_RS08750
uniprot id: D5EK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

583355:CAKA RS08300
gene id: 583355:CAKA_RS08300
uniprot id: D5EJU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

583355:CAKA RS12745
gene id: 583355:CAKA_RS12745
uniprot id: D5EP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS09660
gene id: 583355:CAKA_RS09660
uniprot id: D5EKQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

583355:CAKA RS06515
gene id: 583355:CAKA_RS06515
uniprot id: D5EIU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

583355:CAKA RS14875
gene id: 583355:CAKA_RS14875
uniprot id: D5ERG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS05290
gene id: 583355:CAKA_RS05290
uniprot id: D5EHR9
names: Similarity
messages: Belongs to the SUI1 family.

583355:CAKA RS08510
gene id: 583355:CAKA_RS08510
uniprot id: D5EJY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

583355:CAKA RS04080
gene id: 583355:CAKA_RS04080
uniprot id: D5EQ91
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

583355:CAKA RS16115
gene id: 583355:CAKA_RS16115
uniprot id: D5EKV6
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS09155
gene id: 583355:CAKA_RS09155
uniprot id: D5EKB3
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

583355:CAKA RS04130
gene id: 583355:CAKA_RS04130
uniprot id: D5EQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

583355:CAKA RS10575
gene id: 583355:CAKA_RS10575
uniprot id: D5ELL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

583355:CAKA RS11705
gene id: 583355:CAKA_RS11705
uniprot id: D5EMY4
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

583355:CAKA RS08030
gene id: 583355:CAKA_RS08030
uniprot id: D5EJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

583355:CAKA RS13895
gene id: 583355:CAKA_RS13895
uniprot id: D5EQJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583355:CAKA RS03745
gene id: 583355:CAKA_RS03745
uniprot id: D5EQ28
names: Similarity
messages: Belongs to the acetyltransferase family. ArgA subfamily.

583355:CAKA RS03625
gene id: 583355:CAKA_RS03625
uniprot id: D5EPN3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

583355:CAKA RS04560
gene id: 583355:CAKA_RS04560
uniprot id: D5EQW6
names: Similarity
messages: Belongs to the thioredoxin family.

583355:CAKA RS11980
gene id: 583355:CAKA_RS11980
uniprot id: D5ENF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

583355:CAKA RS13425
gene id: 583355:CAKA_RS13425
uniprot id: D5EPY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

583355:CAKA RS14670
gene id: 583355:CAKA_RS14670
uniprot id: D5ERB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

583355:CAKA RS04450
gene id: 583355:CAKA_RS04450
uniprot id: D5EQU3
names: Similarity
messages: Belongs to the UPF0758 family.

583355:CAKA RS07305
gene id: 583355:CAKA_RS07305
uniprot id: D5EJ99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

583355:CAKA RS12295
gene id: 583355:CAKA_RS12295
uniprot id: D5ENL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

583355:CAKA RS13580
gene id: 583355:CAKA_RS13580
uniprot id: D5EQ14
names: Similarity
messages: Belongs to the histone deacetylase family.

583355:CAKA RS06055
gene id: 583355:CAKA_RS06055
uniprot id: D5EIJ0
names: Similarity
messages: Belongs to the peptidase S24 family.

583355:CAKA RS02590
gene id: 583355:CAKA_RS02590
uniprot id: D5ENQ3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

583355:CAKA RS03410
gene id: 583355:CAKA_RS03410
uniprot id: D5EPI9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583355:CAKA RS14675
gene id: 583355:CAKA_RS14675
uniprot id: D5ERB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

583355:CAKA RS05215
gene id: 583355:CAKA_RS05215
uniprot id: D5EHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

583355:CAKA RS00975
gene id: 583355:CAKA_RS00975
uniprot id: D5ELQ8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

583355:CAKA RS13250
gene id: 583355:CAKA_RS13250
uniprot id: D5EPU9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

583355:CAKA RS01225
gene id: 583355:CAKA_RS01225
uniprot id: D5ELW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

583355:CAKA RS08195
gene id: 583355:CAKA_RS08195
uniprot id: D5EJS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

583355:CAKA RS12160
gene id: 583355:CAKA_RS12160
uniprot id: D5ENI7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

583355:CAKA RS07755
gene id: 583355:CAKA_RS07755
uniprot id: D5EJI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

583355:CAKA RS14035
gene id: 583355:CAKA_RS14035
uniprot id: D5EQM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

583355:CAKA RS12765
gene id: 583355:CAKA_RS12765
uniprot id: D5EP75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583355:CAKA RS10930
gene id: 583355:CAKA_RS10930
uniprot id: D5EM57
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS01665
gene id: 583355:CAKA_RS01665
uniprot id: D5EMG8
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

583355:CAKA RS15115
gene id: 583355:CAKA_RS15115
uniprot id: D5EI14
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS14700
gene id: 583355:CAKA_RS14700
uniprot id: D5ERC4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

583355:CAKA RS00210
gene id: 583355:CAKA_RS00210
uniprot id: D5EKX0
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS08645
gene id: 583355:CAKA_RS08645
uniprot id: D5EK15
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS08590
gene id: 583355:CAKA_RS08590
uniprot id: D5EK03
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

583355:CAKA RS03015
gene id: 583355:CAKA_RS03015
uniprot id: D5ENZ2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS02425
gene id: 583355:CAKA_RS02425
uniprot id: D5EN92
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS05805
gene id: 583355:CAKA_RS05805
uniprot id: D5EIE3
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS09785
gene id: 583355:CAKA_RS09785
uniprot id: D5EKT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS12280
gene id: 583355:CAKA_RS12280
uniprot id: D5ENL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS07840
gene id: 583355:CAKA_RS07840
uniprot id: D5EJK4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

583355:CAKA RS15700
gene id: 583355:CAKA_RS15700
uniprot id: D5EN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS04205
gene id: 583355:CAKA_RS04205
uniprot id: D5EQB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583355:CAKA RS10185
gene id: 583355:CAKA_RS10185
uniprot id: D5ELD2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583355:CAKA RS13705
gene id: 583355:CAKA_RS13705
uniprot id: D5EQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS12820
gene id: 583355:CAKA_RS12820
uniprot id: D5EP86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

583355:CAKA RS10670
gene id: 583355:CAKA_RS10670
uniprot id: D5EM08
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07135
gene id: 583355:CAKA_RS07135
uniprot id: D5EJ65
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

583355:CAKA RS07620
gene id: 583355:CAKA_RS07620
uniprot id: D5EJG0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

583355:CAKA RS12285
gene id: 583355:CAKA_RS12285
uniprot id: D5ENL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

583355:CAKA RS00695
gene id: 583355:CAKA_RS00695
uniprot id: D5EL74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

583355:CAKA RS14750
gene id: 583355:CAKA_RS14750
uniprot id: D5ERD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS08570
gene id: 583355:CAKA_RS08570
uniprot id: D5EJZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

583355:CAKA RS11830
gene id: 583355:CAKA_RS11830
uniprot id: D5ENC2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583355:CAKA RS05310
gene id: 583355:CAKA_RS05310
uniprot id: D5EHS3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

583355:CAKA RS15255
gene id: 583355:CAKA_RS15255
uniprot id: D5EI44
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07145
gene id: 583355:CAKA_RS07145
uniprot id: D5EJ67
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS09945
gene id: 583355:CAKA_RS09945
uniprot id: D5EKW2
names: Similarity
messages: Belongs to the HisA/HisF family.

583355:CAKA RS13980
gene id: 583355:CAKA_RS13980
uniprot id: D5EQL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

583355:CAKA RS14195
gene id: 583355:CAKA_RS14195
uniprot id: D5EQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

583355:CAKA RS06105
gene id: 583355:CAKA_RS06105
uniprot id: D5EIJ5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

583355:CAKA RS01130
gene id: 583355:CAKA_RS01130
uniprot id: D5ELU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS12985
gene id: 583355:CAKA_RS12985
uniprot id: D5EPB9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

583355:CAKA RS07595
gene id: 583355:CAKA_RS07595
uniprot id: D5EJF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

583355:CAKA RS10730
gene id: 583355:CAKA_RS10730
uniprot id: D5EM20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

583355:CAKA RS02070
gene id: 583355:CAKA_RS02070
uniprot id: D5EN20
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS10120
gene id: 583355:CAKA_RS10120
uniprot id: D5ELB9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

583355:CAKA RS01100
gene id: 583355:CAKA_RS01100
uniprot id: D5ELT3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS05670
gene id: 583355:CAKA_RS05670
uniprot id: D5EIB7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS03380
gene id: 583355:CAKA_RS03380
uniprot id: D5EPI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

583355:CAKA RS03360
gene id: 583355:CAKA_RS03360
uniprot id: D5EPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

583355:CAKA RS05335
gene id: 583355:CAKA_RS05335
uniprot id: D5EHS8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

583355:CAKA RS12360
gene id: 583355:CAKA_RS12360
uniprot id: D5ENM7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

583355:CAKA RS09260
gene id: 583355:CAKA_RS09260
uniprot id: D5EKD4
names: Similarity
messages: Belongs to the asp23 family.

583355:CAKA RS09405
gene id: 583355:CAKA_RS09405
uniprot id: D5EKK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

583355:CAKA RS10420
gene id: 583355:CAKA_RS10420
uniprot id: D5ELI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS05850
gene id: 583355:CAKA_RS05850
uniprot id: D5EIF2
names: Similarity
messages: Belongs to the sigma-54 factor family.

583355:CAKA RS10020
gene id: 583355:CAKA_RS10020
uniprot id: D5EL99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

583355:CAKA RS11630
gene id: 583355:CAKA_RS11630
uniprot id: D5EMW9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

583355:CAKA RS15245
gene id: 583355:CAKA_RS15245
uniprot id: D5EI42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

583355:CAKA RS03705
gene id: 583355:CAKA_RS03705
uniprot id: D5EPQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS15280
gene id: 583355:CAKA_RS15280
uniprot id: D5EI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

583355:CAKA RS16400
gene id: 583355:CAKA_RS16400
uniprot id: D5EIL6
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS03945
gene id: 583355:CAKA_RS03945
uniprot id: D5EQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

583355:CAKA RS01925
gene id: 583355:CAKA_RS01925
uniprot id: D5EMM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

583355:CAKA RS07980
gene id: 583355:CAKA_RS07980
uniprot id: D5EJN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

583355:CAKA RS00620
gene id: 583355:CAKA_RS00620
uniprot id: D5EL57
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS16220
gene id: 583355:CAKA_RS16220
uniprot id: D5EMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

583355:CAKA RS12335
gene id: 583355:CAKA_RS12335
uniprot id: D5ENM2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

583355:CAKA RS09585
gene id: 583355:CAKA_RS09585
uniprot id: D5EKP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS03880
gene id: 583355:CAKA_RS03880
uniprot id: D5EQ52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS08890
gene id: 583355:CAKA_RS08890
uniprot id: D5EK64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

583355:CAKA RS13350
gene id: 583355:CAKA_RS13350
uniprot id: D5EPW8
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS05195
gene id: 583355:CAKA_RS05195
uniprot id: D5EHQ0
names: Similarity
messages: Belongs to the CapA family.

583355:CAKA RS12710
gene id: 583355:CAKA_RS12710
uniprot id: D5EP64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS02365
gene id: 583355:CAKA_RS02365
uniprot id: D5EN80
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

583355:CAKA RS08640
gene id: 583355:CAKA_RS08640
uniprot id: D5EK14
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

583355:CAKA RS11570
gene id: 583355:CAKA_RS11570
uniprot id: D5EMV7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

583355:CAKA RS02345
gene id: 583355:CAKA_RS02345
uniprot id: D5EN76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS05790
gene id: 583355:CAKA_RS05790
uniprot id: D5EIE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

583355:CAKA RS05170
gene id: 583355:CAKA_RS05170
uniprot id: D5EHP6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

583355:CAKA RS14280
gene id: 583355:CAKA_RS14280
uniprot id: D5EQR9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

583355:CAKA RS09335
gene id: 583355:CAKA_RS09335
uniprot id: D5EKJ1
names: Similarity
messages: Belongs to the UPF0047 family.

583355:CAKA RS07825
gene id: 583355:CAKA_RS07825
uniprot id: D5EJK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

583355:CAKA RS05485
gene id: 583355:CAKA_RS05485
uniprot id: D5EHV8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

583355:CAKA RS00520
gene id: 583355:CAKA_RS00520
uniprot id: D5EL35
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

583355:CAKA RS07500
gene id: 583355:CAKA_RS07500
uniprot id: D5EJD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

583355:CAKA RS01990
gene id: 583355:CAKA_RS01990
uniprot id: D5EN05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS04350
gene id: 583355:CAKA_RS04350
uniprot id: D5EQE6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

583355:CAKA RS14825
gene id: 583355:CAKA_RS14825
uniprot id: D5ERF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

583355:CAKA RS14950
gene id: 583355:CAKA_RS14950
uniprot id: D5EHX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

583355:CAKA RS11165
gene id: 583355:CAKA_RS11165
uniprot id: D5EMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

583355:CAKA RS08870
gene id: 583355:CAKA_RS08870
uniprot id: D5EK60
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

583355:CAKA RS01105
gene id: 583355:CAKA_RS01105
uniprot id: D5ELT4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

583355:CAKA RS04640
gene id: 583355:CAKA_RS04640
uniprot id: D5EQY4
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

583355:CAKA RS15090
gene id: 583355:CAKA_RS15090
uniprot id: D5EI09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

583355:CAKA RS08875
gene id: 583355:CAKA_RS08875
uniprot id: D5EK61
names: Similarity
messages: Belongs to the ribF family.

583355:CAKA RS10785
gene id: 583355:CAKA_RS10785
uniprot id: D5EM31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

583355:CAKA RS14650
gene id: 583355:CAKA_RS14650
uniprot id: D5ERB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

583355:CAKA RS11295
gene id: 583355:CAKA_RS11295
uniprot id: D5EMP9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

583355:CAKA RS13740
gene id: 583355:CAKA_RS13740
uniprot id: D5EQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583355:CAKA RS06480
gene id: 583355:CAKA_RS06480
uniprot id: D5EIT3
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS12260
gene id: 583355:CAKA_RS12260
uniprot id: D5ENK7
names: Similarity
messages: Belongs to the ParB family.

583355:CAKA RS12025
gene id: 583355:CAKA_RS12025
uniprot id: D5ENG1
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS11550
gene id: 583355:CAKA_RS11550
uniprot id: D5EMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

583355:CAKA RS13375
gene id: 583355:CAKA_RS13375
uniprot id: D5EPX3
names: Similarity
messages: Belongs to the Nth/MutY family.

583355:CAKA RS10095
gene id: 583355:CAKA_RS10095
uniprot id: D5ELB4
names: Similarity
messages: Belongs to the Fur family.

583355:CAKA RS08320
gene id: 583355:CAKA_RS08320
uniprot id: D5EJU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

583355:CAKA RS14115
gene id: 583355:CAKA_RS14115
uniprot id: D5EQN8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

583355:CAKA RS10425
gene id: 583355:CAKA_RS10425
uniprot id: D5ELI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

583355:CAKA RS06825
gene id: 583355:CAKA_RS06825
uniprot id: D5EJ04
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS13150
gene id: 583355:CAKA_RS13150
uniprot id: D5EPT0
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS13945
gene id: 583355:CAKA_RS13945
uniprot id: D5EQK3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

583355:CAKA RS10300
gene id: 583355:CAKA_RS10300
uniprot id: D5ELF5
names: Similarity
messages: Belongs to the creatininase superfamily.

583355:CAKA RS13710
gene id: 583355:CAKA_RS13710
uniprot id: D5EQF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

583355:CAKA RS07085
gene id: 583355:CAKA_RS07085
uniprot id: D5EJ56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

583355:CAKA RS01585
gene id: 583355:CAKA_RS01585
uniprot id: D5EMF2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

583355:CAKA RS12900
gene id: 583355:CAKA_RS12900
uniprot id: D5EPA2
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

583355:CAKA RS10105
gene id: 583355:CAKA_RS10105
uniprot id: D5ELB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

583355:CAKA RS11995
gene id: 583355:CAKA_RS11995
uniprot id: D5ENF5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

583355:CAKA RS07020
gene id: 583355:CAKA_RS07020
uniprot id: D5EJ43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

583355:CAKA RS07545
gene id: 583355:CAKA_RS07545
uniprot id: D5EJE5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583355:CAKA RS03710
gene id: 583355:CAKA_RS03710
uniprot id: D5EPQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

583355:CAKA RS07090
gene id: 583355:CAKA_RS07090
uniprot id: D5EJ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

583355:CAKA RS06620
gene id: 583355:CAKA_RS06620
uniprot id: D5EIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

583355:CAKA RS12290
gene id: 583355:CAKA_RS12290
uniprot id: D5ENL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

583355:CAKA RS12945
gene id: 583355:CAKA_RS12945
uniprot id: D5EPB1
names: Similarity
messages: Belongs to the aspartokinase family.

583355:CAKA RS00310
gene id: 583355:CAKA_RS00310
uniprot id: D5EKZ1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

583355:CAKA RS14920
gene id: 583355:CAKA_RS14920
uniprot id: D5EHX3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS11695
gene id: 583355:CAKA_RS11695
uniprot id: D5EMY2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

583355:CAKA RS09780
gene id: 583355:CAKA_RS09780
uniprot id: D5EKS9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS10335
gene id: 583355:CAKA_RS10335
uniprot id: D5ELG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

583355:CAKA RS07140
gene id: 583355:CAKA_RS07140
uniprot id: D5EJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS07120
gene id: 583355:CAKA_RS07120
uniprot id: D5EJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

583355:CAKA RS03870
gene id: 583355:CAKA_RS03870
uniprot id: D5EQ50
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

583355:CAKA RS14945
gene id: 583355:CAKA_RS14945
uniprot id: D5EHX8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

583355:CAKA RS05200
gene id: 583355:CAKA_RS05200
uniprot id: D5EHQ1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

583355:CAKA RS15045
gene id: 583355:CAKA_RS15045
uniprot id: D5EI00
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

583355:CAKA RS10715
gene id: 583355:CAKA_RS10715
uniprot id: D5EM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

583355:CAKA RS10525
gene id: 583355:CAKA_RS10525
uniprot id: D5ELK2
names: Similarity
messages: Belongs to the peptidase S41A family.

583355:CAKA RS14095
gene id: 583355:CAKA_RS14095
uniprot id: D5EQN4
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

583355:CAKA RS07215
gene id: 583355:CAKA_RS07215
uniprot id: D5EJ79
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

583355:CAKA RS00760
gene id: 583355:CAKA_RS00760
uniprot id: D5EL86
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

583355:CAKA RS08280
gene id: 583355:CAKA_RS08280
uniprot id: D5EJU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

583355:CAKA RS07155
gene id: 583355:CAKA_RS07155
uniprot id: D5EJ69
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS04390
gene id: 583355:CAKA_RS04390
uniprot id: D5EQT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

583355:CAKA RS10215
gene id: 583355:CAKA_RS10215
uniprot id: D5ELD8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

583355:CAKA RS10500
gene id: 583355:CAKA_RS10500
uniprot id: D5ELJ7
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

583355:CAKA RS07805
gene id: 583355:CAKA_RS07805
uniprot id: D5EJJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

583355:CAKA RS14190
gene id: 583355:CAKA_RS14190
uniprot id: D5EQQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS07855
gene id: 583355:CAKA_RS07855
uniprot id: D5EJK7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

583355:CAKA RS07485
gene id: 583355:CAKA_RS07485
uniprot id: D5EJD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583355:CAKA RS07830
gene id: 583355:CAKA_RS07830
uniprot id: D5EJK2
names: Similarity
messages: Belongs to the Skp family.

583355:CAKA RS03050
gene id: 583355:CAKA_RS03050
uniprot id: D5ENZ9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

583355:CAKA RS08150
gene id: 583355:CAKA_RS08150
uniprot id: D5EJR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS14285
gene id: 583355:CAKA_RS14285
uniprot id: D5EQS0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

583355:CAKA RS04445
gene id: 583355:CAKA_RS04445
uniprot id: D5EQU2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

583355:CAKA RS03250
gene id: 583355:CAKA_RS03250
uniprot id: D5EPG0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

583355:CAKA RS08315
gene id: 583355:CAKA_RS08315
uniprot id: D5EJU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

583355:CAKA RS12895
gene id: 583355:CAKA_RS12895
uniprot id: D5EPA1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583355:CAKA RS10325
gene id: 583355:CAKA_RS10325
uniprot id: D5ELG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

583355:CAKA RS05775
gene id: 583355:CAKA_RS05775
uniprot id: D5EID7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

583355:CAKA RS09485
gene id: 583355:CAKA_RS09485
uniprot id: D5EKM0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

583355:CAKA RS02105
gene id: 583355:CAKA_RS02105
uniprot id: D5EN27
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

583355:CAKA RS11725
gene id: 583355:CAKA_RS11725
uniprot id: D5EMY8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

583355:CAKA RS11160
gene id: 583355:CAKA_RS11160
uniprot id: D5EMA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

583355:CAKA RS02415
gene id: 583355:CAKA_RS02415
uniprot id: D5EN90
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS09345
gene id: 583355:CAKA_RS09345
uniprot id: D5EKJ3
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

583355:CAKA RS11955
gene id: 583355:CAKA_RS11955
uniprot id: D5ENE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS12770
gene id: 583355:CAKA_RS12770
uniprot id: D5EP76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583355:CAKA RS02570
gene id: 583355:CAKA_RS02570
uniprot id: D5ENP8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS05910
gene id: 583355:CAKA_RS05910
uniprot id: D5EIG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS08220
gene id: 583355:CAKA_RS08220
uniprot id: D5EJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583355:CAKA RS01815
gene id: 583355:CAKA_RS01815
uniprot id: D5EMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

583355:CAKA RS14490
gene id: 583355:CAKA_RS14490
uniprot id: D5ER83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS07810
gene id: 583355:CAKA_RS07810
uniprot id: D5EJJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS15785
gene id: 583355:CAKA_RS15785
uniprot id: D5EPQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS11050
gene id: 583355:CAKA_RS11050
uniprot id: D5EM80
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

583355:CAKA RS01610
gene id: 583355:CAKA_RS01610
uniprot id: D5EMF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583355:CAKA RS05185
gene id: 583355:CAKA_RS05185
uniprot id: D5EHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

583355:CAKA RS02440
gene id: 583355:CAKA_RS02440
uniprot id: D5EN95
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS03920
gene id: 583355:CAKA_RS03920
uniprot id: D5EQ60
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

583355:CAKA RS11410
gene id: 583355:CAKA_RS11410
uniprot id: D5EMS5
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS07300
gene id: 583355:CAKA_RS07300
uniprot id: D5EJ98
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

583355:CAKA RS12250
gene id: 583355:CAKA_RS12250
uniprot id: D5ENK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS12505
gene id: 583355:CAKA_RS12505
uniprot id: D5EP24
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

583355:CAKA RS13470
gene id: 583355:CAKA_RS13470
uniprot id: D5EPZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

583355:CAKA RS15925
gene id: 583355:CAKA_RS15925
uniprot id: D5EIK2
names: Similarity
messages: Belongs to the SCO1/2 family.

583355:CAKA RS02420
gene id: 583355:CAKA_RS02420
uniprot id: D5EN91
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS09180
gene id: 583355:CAKA_RS09180
uniprot id: D5EKB8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

583355:CAKA RS00795
gene id: 583355:CAKA_RS00795
uniprot id: D5ELM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

583355:CAKA RS06360
gene id: 583355:CAKA_RS06360
uniprot id: D5EIR0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

583355:CAKA RS01000
gene id: 583355:CAKA_RS01000
uniprot id: D5ELR3
names: Similarity
messages: Belongs to the peptidase M29 family.

583355:CAKA RS10650
gene id: 583355:CAKA_RS10650
uniprot id: D5EM03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

583355:CAKA RS05585
gene id: 583355:CAKA_RS05585
uniprot id: D5EIA2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

583355:CAKA RS11130
gene id: 583355:CAKA_RS11130
uniprot id: D5EM96
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS06745
gene id: 583355:CAKA_RS06745
uniprot id: D5EIY5
names: Similarity
messages: Belongs to the cytochrome c-552 family.

583355:CAKA RS10310
gene id: 583355:CAKA_RS10310
uniprot id: D5ELF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

583355:CAKA RS00380
gene id: 583355:CAKA_RS00380
uniprot id: D5EL05
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

583355:CAKA RS08950
gene id: 583355:CAKA_RS08950
uniprot id: D5EK71
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583355:CAKA RS09425
gene id: 583355:CAKA_RS09425
uniprot id: D5EKK8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583355:CAKA RS07170
gene id: 583355:CAKA_RS07170
uniprot id: D5EJ72
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

583355:CAKA RS11580
gene id: 583355:CAKA_RS11580
uniprot id: D5EMV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583355:CAKA RS11865
gene id: 583355:CAKA_RS11865
uniprot id: D5ENC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS03455
gene id: 583355:CAKA_RS03455
uniprot id: D5EPJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS03005
gene id: 583355:CAKA_RS03005
uniprot id: D5ENZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

583355:CAKA RS15265
gene id: 583355:CAKA_RS15265
uniprot id: D5EI46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

583355:CAKA RS14890
gene id: 583355:CAKA_RS14890
uniprot id: D5EHW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

583355:CAKA RS15230
gene id: 583355:CAKA_RS15230
uniprot id: D5EI39
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS09355
gene id: 583355:CAKA_RS09355
uniprot id: D5EKJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583355:CAKA RS14725
gene id: 583355:CAKA_RS14725
uniprot id: D5ERD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

583355:CAKA RS03915
gene id: 583355:CAKA_RS03915
uniprot id: D5EQ59
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

583355:CAKA RS04040
gene id: 583355:CAKA_RS04040
uniprot id: D5EQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

583355:CAKA RS14265
gene id: 583355:CAKA_RS14265
uniprot id: D5EQR6
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS06310
gene id: 583355:CAKA_RS06310
uniprot id: D5EIQ0
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS12570
gene id: 583355:CAKA_RS12570
uniprot id: D5EP36
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS08915
gene id: 583355:CAKA_RS08915
uniprot id: D5EK69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

583355:CAKA RS12015
gene id: 583355:CAKA_RS12015
uniprot id: D5ENF9
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

583355:CAKA RS14835
gene id: 583355:CAKA_RS14835
uniprot id: D5ERF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

583355:CAKA RS04935
gene id: 583355:CAKA_RS04935
uniprot id: D5EHJ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS13235
gene id: 583355:CAKA_RS13235
uniprot id: D5EPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

583355:CAKA RS00125
gene id: 583355:CAKA_RS00125
uniprot id: D5EKH3
names: Cofactor
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

583355:CAKA RS08490
gene id: 583355:CAKA_RS08490
uniprot id: D5EJY3
names: Subcellular Location Annotation
messages: Cytoplasm

583355:CAKA RS08365
gene id: 583355:CAKA_RS08365
uniprot id: D5EJV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

583355:CAKA RS08040
gene id: 583355:CAKA_RS08040
uniprot id: D5EJP4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

583355:CAKA RS07800
gene id: 583355:CAKA_RS07800
uniprot id: D5EJJ6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

583355:CAKA RS11720
gene id: 583355:CAKA_RS11720
uniprot id: D5EMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

583355:CAKA RS15575
gene id: 583355:CAKA_RS15575
uniprot id: D5EKI6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS14855
gene id: 583355:CAKA_RS14855
uniprot id: D5ERF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583355:CAKA RS15675
gene id: 583355:CAKA_RS15675
uniprot id: D5EMN1
names: Similarity
messages: Belongs to the peptidase M16 family.

583355:CAKA RS12965
gene id: 583355:CAKA_RS12965
uniprot id: D5EPB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583355:CAKA RS08235
gene id: 583355:CAKA_RS08235
uniprot id: D5EJT2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

583355:CAKA RS10475
gene id: 583355:CAKA_RS10475
uniprot id: D5ELJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

583355:CAKA RS03845
gene id: 583355:CAKA_RS03845
uniprot id: D5EQ45
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

583355:CAKA RS14200
gene id: 583355:CAKA_RS14200
uniprot id: D5EQQ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS11205
gene id: 583355:CAKA_RS11205
uniprot id: D5EMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

583355:CAKA RS12145
gene id: 583355:CAKA_RS12145
uniprot id: D5ENI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS11490
gene id: 583355:CAKA_RS11490
uniprot id: D5EMU0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

583355:CAKA RS16135
gene id: 583355:CAKA_RS16135
uniprot id: D5ELD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

583355:CAKA RS12085
gene id: 583355:CAKA_RS12085
uniprot id: D5ENH3
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS11990
gene id: 583355:CAKA_RS11990
uniprot id: D5ENF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

583355:CAKA RS07850
gene id: 583355:CAKA_RS07850
uniprot id: D5EJK6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS10540
gene id: 583355:CAKA_RS10540
uniprot id: D5ELK5
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS01045
gene id: 583355:CAKA_RS01045
uniprot id: D5ELS2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

583355:CAKA RS10695
gene id: 583355:CAKA_RS10695
uniprot id: D5EM13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

583355:CAKA RS08370
gene id: 583355:CAKA_RS08370
uniprot id: D5EJV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

583355:CAKA RS05025
gene id: 583355:CAKA_RS05025
uniprot id: D5EHL5
names: Similarity
messages: Belongs to the peptidase S49 family.

583355:CAKA RS09550
gene id: 583355:CAKA_RS09550
uniprot id: D5EKN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS10690
gene id: 583355:CAKA_RS10690
uniprot id: D5EM12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

583355:CAKA RS06720
gene id: 583355:CAKA_RS06720
uniprot id: D5EIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS11180
gene id: 583355:CAKA_RS11180
uniprot id: D5EMA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS01625
gene id: 583355:CAKA_RS01625
uniprot id: D5EMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

583355:CAKA RS15645
gene id: 583355:CAKA_RS15645
uniprot id: D5ELX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583355:CAKA RS05050
gene id: 583355:CAKA_RS05050
uniprot id: D5EHM1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS08860
gene id: 583355:CAKA_RS08860
uniprot id: D5EK58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

583355:CAKA RS10495
gene id: 583355:CAKA_RS10495
uniprot id: D5ELJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

583355:CAKA RS14075
gene id: 583355:CAKA_RS14075
uniprot id: D5EQN0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

583355:CAKA RS12490
gene id: 583355:CAKA_RS12490
uniprot id: D5EP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583355:CAKA RS09280
gene id: 583355:CAKA_RS09280
uniprot id: D5EKD8
names: Similarity
messages: Belongs to the glutamate synthase family.

583355:CAKA RS14320
gene id: 583355:CAKA_RS14320
uniprot id: D5ER49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583355:CAKA RS08810
gene id: 583355:CAKA_RS08810
uniprot id: D5EK48
names: Similarity
messages: Belongs to the Fur family.

583355:CAKA RS10770
gene id: 583355:CAKA_RS10770
uniprot id: D5EM28
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

583355:CAKA RS11835
gene id: 583355:CAKA_RS11835
uniprot id: D5ENC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

583355:CAKA RS08360
gene id: 583355:CAKA_RS08360
uniprot id: D5EJV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

583355:CAKA RS09790
gene id: 583355:CAKA_RS09790
uniprot id: D5EKT1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

583355:CAKA RS03865
gene id: 583355:CAKA_RS03865
uniprot id: D5EQ49
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS12545
gene id: 583355:CAKA_RS12545
uniprot id: D5EP32
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

583355:CAKA RS14495
gene id: 583355:CAKA_RS14495
uniprot id: D5ER84
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS01660
gene id: 583355:CAKA_RS01660
uniprot id: D5EMG7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

583355:CAKA RS12690
gene id: 583355:CAKA_RS12690
uniprot id: D5EP60
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

583355:CAKA RS10110
gene id: 583355:CAKA_RS10110
uniprot id: D5ELB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

583355:CAKA RS08130
gene id: 583355:CAKA_RS08130
uniprot id: D5EJR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

583355:CAKA RS05530
gene id: 583355:CAKA_RS05530
uniprot id: D5EHW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

583355:CAKA RS02385
gene id: 583355:CAKA_RS02385
uniprot id: D5EN84
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583355:CAKA RS11090
gene id: 583355:CAKA_RS11090
uniprot id: D5EM88
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

583355:CAKA RS12300
gene id: 583355:CAKA_RS12300
uniprot id: D5ENL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

583355:CAKA RS02890
gene id: 583355:CAKA_RS02890
uniprot id: D5ENW6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

583355:CAKA RS14815
gene id: 583355:CAKA_RS14815
uniprot id: D5ERE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

583355:CAKA RS13860
gene id: 583355:CAKA_RS13860
uniprot id: D5EQI6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

583355:CAKA RS09750
gene id: 583355:CAKA_RS09750
uniprot id: D5EKS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS14880
gene id: 583355:CAKA_RS14880
uniprot id: D5ERG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

583355:CAKA RS12810
gene id: 583355:CAKA_RS12810
uniprot id: D5EP84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583355:CAKA RS00785
gene id: 583355:CAKA_RS00785
uniprot id: D5ELL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

583355:CAKA RS15210
gene id: 583355:CAKA_RS15210
uniprot id: D5EI35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

583355:CAKA RS06560
gene id: 583355:CAKA_RS06560
uniprot id: D5EIU9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

583355:CAKA RS15080
gene id: 583355:CAKA_RS15080
uniprot id: D5EI07
names: Similarity
messages: Belongs to the GSP E family.

583355:CAKA RS07950
gene id: 583355:CAKA_RS07950
uniprot id: D5EJM6
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS13445
gene id: 583355:CAKA_RS13445
uniprot id: D5EPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

583355:CAKA RS05825
gene id: 583355:CAKA_RS05825
uniprot id: D5EIE7
names: Subcellular Location Annotation
messages: Membrane

583355:CAKA RS11730
gene id: 583355:CAKA_RS11730
uniprot id: D5EMY9
names: Similarity
messages: Belongs to the citrate synthase family.

583355:CAKA RS13730
gene id: 583355:CAKA_RS13730
uniprot id: D5EQG2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

583355:CAKA RS00885
gene id: 583355:CAKA_RS00885
uniprot id: D5ELN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583355:CAKA RS09050
gene id: 583355:CAKA_RS09050
uniprot id: D5EK91
names: Similarity
messages: Belongs to the Dps family.

583355:CAKA RS13245
gene id: 583355:CAKA_RS13245
uniprot id: D5EPU8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.