583345:MMOL RS10025
gene id: 583345:MMOL_RS10025
uniprot id: C6WYG1
names: Similarity
messages: Belongs to the pyruvate kinase family.

583345:MMOL RS02845
gene id: 583345:MMOL_RS02845
uniprot id: C6WU72
names: Similarity
messages: Belongs to the UPF0047 family.

583345:MMOL RS03380
gene id: 583345:MMOL_RS03380
uniprot id: C6WUH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583345:MMOL RS08875
gene id: 583345:MMOL_RS08875
uniprot id: C6WXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

583345:MMOL RS07850
gene id: 583345:MMOL_RS07850
uniprot id: C6WX04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

583345:MMOL RS02650
gene id: 583345:MMOL_RS02650
uniprot id: C6WU33
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

583345:MMOL RS03910
gene id: 583345:MMOL_RS03910
uniprot id: C6WUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS11820
gene id: 583345:MMOL_RS11820
uniprot id: C6WTU8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

583345:MMOL RS11815
gene id: 583345:MMOL_RS11815
uniprot id: C6WTU7
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04445
gene id: 583345:MMOL_RS04445
uniprot id: C6WV33
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

583345:MMOL RS05270
gene id: 583345:MMOL_RS05270
uniprot id: C6WVJ9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

583345:MMOL RS07745
gene id: 583345:MMOL_RS07745
uniprot id: C6WWY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS10505
gene id: 583345:MMOL_RS10505
uniprot id: C6WZ29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

583345:MMOL RS09840
gene id: 583345:MMOL_RS09840
uniprot id: C6WYC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

583345:MMOL RS06755
gene id: 583345:MMOL_RS06755
uniprot id: C6WWD5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583345:MMOL RS04875
gene id: 583345:MMOL_RS04875
uniprot id: C6WVB9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

583345:MMOL RS09465
gene id: 583345:MMOL_RS09465
uniprot id: C6WXX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

583345:MMOL RS11800
gene id: 583345:MMOL_RS11800
uniprot id: C6WTU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

583345:MMOL RS03700
gene id: 583345:MMOL_RS03700
uniprot id: C6WUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

583345:MMOL RS03940
gene id: 583345:MMOL_RS03940
uniprot id: C6WUT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

583345:MMOL RS01575
gene id: 583345:MMOL_RS01575
uniprot id: C6WSX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

583345:MMOL RS07610
gene id: 583345:MMOL_RS07610
uniprot id: C6WWV6
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

583345:MMOL RS03615
gene id: 583345:MMOL_RS03615
uniprot id: C6WUM1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

583345:MMOL RS01510
gene id: 583345:MMOL_RS01510
uniprot id: C6WSW5
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS02965
gene id: 583345:MMOL_RS02965
uniprot id: C6WU96
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

583345:MMOL RS01600
gene id: 583345:MMOL_RS01600
uniprot id: C6WSY3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

583345:MMOL RS02615
gene id: 583345:MMOL_RS02615
uniprot id: C6WU26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

583345:MMOL RS03705
gene id: 583345:MMOL_RS03705
uniprot id: C6WUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

583345:MMOL RS10175
gene id: 583345:MMOL_RS10175
uniprot id: C6WYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS02830
gene id: 583345:MMOL_RS02830
uniprot id: C6WU69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

583345:MMOL RS06410
gene id: 583345:MMOL_RS06410
uniprot id: C6WW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

583345:MMOL RS06535
gene id: 583345:MMOL_RS06535
uniprot id: C6WW95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

583345:MMOL RS01370
gene id: 583345:MMOL_RS01370
uniprot id: C6WST7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

583345:MMOL RS02585
gene id: 583345:MMOL_RS02585
uniprot id: C6WU20
names: Similarity
messages: Belongs to the YkuD family.

583345:MMOL RS05820
gene id: 583345:MMOL_RS05820
uniprot id: C6WVV5
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

583345:MMOL RS04745
gene id: 583345:MMOL_RS04745
uniprot id: C6WV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

583345:MMOL RS08110
gene id: 583345:MMOL_RS08110
uniprot id: C6WX54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

583345:MMOL RS08125
gene id: 583345:MMOL_RS08125
uniprot id: C6WX57
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

583345:MMOL RS02970
gene id: 583345:MMOL_RS02970
uniprot id: C6WU97
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

583345:MMOL RS01930
gene id: 583345:MMOL_RS01930
uniprot id: C6WTG5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

583345:MMOL RS05430
gene id: 583345:MMOL_RS05430
uniprot id: C6WVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS00100
gene id: 583345:MMOL_RS00100
uniprot id: C6WY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

583345:MMOL RS11515
gene id: 583345:MMOL_RS11515
uniprot id: C6WTN9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

583345:MMOL RS04600
gene id: 583345:MMOL_RS04600
uniprot id: C6WV64
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

583345:MMOL RS06405
gene id: 583345:MMOL_RS06405
uniprot id: C6WW68
names: Similarity
messages: Belongs to the MotB family.

583345:MMOL RS03405
gene id: 583345:MMOL_RS03405
uniprot id: C6WUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

583345:MMOL RS01065
gene id: 583345:MMOL_RS01065
uniprot id: C6WSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

583345:MMOL RS02260
gene id: 583345:MMOL_RS02260
uniprot id: C6WTN2
names: Similarity
messages: Belongs to the peptidase C40 family.

583345:MMOL RS11525
gene id: 583345:MMOL_RS11525
uniprot id: C6WTP1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

583345:MMOL RS10665
gene id: 583345:MMOL_RS10665
uniprot id: C6WZ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

583345:MMOL RS04540
gene id: 583345:MMOL_RS04540
uniprot id: C6WV53
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

583345:MMOL RS07975
gene id: 583345:MMOL_RS07975
uniprot id: C6WX29
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

583345:MMOL RS04070
gene id: 583345:MMOL_RS04070
uniprot id: C6WUV9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

583345:MMOL RS02420
gene id: 583345:MMOL_RS02420
uniprot id: C6WTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

583345:MMOL RS03335
gene id: 583345:MMOL_RS03335
uniprot id: C6WUG4
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

583345:MMOL RS01965
gene id: 583345:MMOL_RS01965
uniprot id: C6WTH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

583345:MMOL RS06460
gene id: 583345:MMOL_RS06460
uniprot id: C6WW80
names: Similarity
messages: Belongs to the MotB family.

583345:MMOL RS08585
gene id: 583345:MMOL_RS08585
uniprot id: C6WXE9
names: Similarity
messages: Belongs to the peptidase M1 family.

583345:MMOL RS06670
gene id: 583345:MMOL_RS06670
uniprot id: C6WWC2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583345:MMOL RS09495
gene id: 583345:MMOL_RS09495
uniprot id: C6WXX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583345:MMOL RS00440
gene id: 583345:MMOL_RS00440
uniprot id: C6WYM6
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS06060
gene id: 583345:MMOL_RS06060
uniprot id: C6WW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

583345:MMOL RS01475
gene id: 583345:MMOL_RS01475
uniprot id: C6WSV8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

583345:MMOL RS03595
gene id: 583345:MMOL_RS03595
uniprot id: C6WUL6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

583345:MMOL RS03685
gene id: 583345:MMOL_RS03685
uniprot id: C6WUN5
names: Similarity
messages: Belongs to the YkuD family.

583345:MMOL RS05165
gene id: 583345:MMOL_RS05165
uniprot id: C6WVH8
names: Similarity
messages: Belongs to the MoaD family.

583345:MMOL RS04065
gene id: 583345:MMOL_RS04065
uniprot id: C6WUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

583345:MMOL RS07750
gene id: 583345:MMOL_RS07750
uniprot id: C6WWY4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

583345:MMOL RS09280
gene id: 583345:MMOL_RS09280
uniprot id: C6WXT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

583345:MMOL RS06270
gene id: 583345:MMOL_RS06270
uniprot id: C6WW42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

583345:MMOL RS05795
gene id: 583345:MMOL_RS05795
uniprot id: C6WVV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

583345:MMOL RS02930
gene id: 583345:MMOL_RS02930
uniprot id: C6WU89
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

583345:MMOL RS04555
gene id: 583345:MMOL_RS04555
uniprot id: C6WV55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

583345:MMOL RS01360
gene id: 583345:MMOL_RS01360
uniprot id: C6WST5
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

583345:MMOL RS10935
gene id: 583345:MMOL_RS10935
uniprot id: C6WT02
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

583345:MMOL RS05905
gene id: 583345:MMOL_RS05905
uniprot id: C6WVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

583345:MMOL RS07585
gene id: 583345:MMOL_RS07585
uniprot id: C6WWV1
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS10305
gene id: 583345:MMOL_RS10305
uniprot id: C6WYL6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

583345:MMOL RS06005
gene id: 583345:MMOL_RS06005
uniprot id: C6WVZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

583345:MMOL RS00075
gene id: 583345:MMOL_RS00075
uniprot id: C6WY29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS08570
gene id: 583345:MMOL_RS08570
uniprot id: C6WXE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

583345:MMOL RS10920
gene id: 583345:MMOL_RS10920
uniprot id: C6WSZ9
names: Subcellular Location Annotation
messages: Cytoplasm

583345:MMOL RS01830
gene id: 583345:MMOL_RS01830
uniprot id: C6WTE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

583345:MMOL RS06500
gene id: 583345:MMOL_RS06500
uniprot id: C6WW88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

583345:MMOL RS02580
gene id: 583345:MMOL_RS02580
uniprot id: C6WU19
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

583345:MMOL RS07370
gene id: 583345:MMOL_RS07370
uniprot id: C6WWQ9
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS10140
gene id: 583345:MMOL_RS10140
uniprot id: C6WYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

583345:MMOL RS04985
gene id: 583345:MMOL_RS04985
uniprot id: C6WVE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

583345:MMOL RS04890
gene id: 583345:MMOL_RS04890
uniprot id: C6WVC2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

583345:MMOL RS04775
gene id: 583345:MMOL_RS04775
uniprot id: C6WV99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

583345:MMOL RS11740
gene id: 583345:MMOL_RS11740
uniprot id: C6WTT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

583345:MMOL RS10440
gene id: 583345:MMOL_RS10440
uniprot id: C6WZ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

583345:MMOL RS05300
gene id: 583345:MMOL_RS05300
uniprot id: C6WVK4
names: Similarity
messages: Belongs to the MQO family.

583345:MMOL RS08290
gene id: 583345:MMOL_RS08290
uniprot id: C6WX90
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS06700
gene id: 583345:MMOL_RS06700
uniprot id: C6WWC6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

583345:MMOL RS11835
gene id: 583345:MMOL_RS11835
uniprot id: C6WTV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

583345:MMOL RS03660
gene id: 583345:MMOL_RS03660
uniprot id: C6WUN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

583345:MMOL RS06280
gene id: 583345:MMOL_RS06280
uniprot id: C6WW44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

583345:MMOL RS04755
gene id: 583345:MMOL_RS04755
uniprot id: C6WV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

583345:MMOL RS00490
gene id: 583345:MMOL_RS00490
uniprot id: C6WYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583345:MMOL RS07200
gene id: 583345:MMOL_RS07200
uniprot id: C6WWM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

583345:MMOL RS03500
gene id: 583345:MMOL_RS03500
uniprot id: C6WUJ7
names: Similarity
messages: Belongs to the BolA/IbaG family.

583345:MMOL RS09730
gene id: 583345:MMOL_RS09730
uniprot id: C6WYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS10155
gene id: 583345:MMOL_RS10155
uniprot id: C6WYI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

583345:MMOL RS10150
gene id: 583345:MMOL_RS10150
uniprot id: C6WYI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

583345:MMOL RS11810
gene id: 583345:MMOL_RS11810
uniprot id: C6WTU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

583345:MMOL RS07010
gene id: 583345:MMOL_RS07010
uniprot id: C6WWI6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01605
gene id: 583345:MMOL_RS01605
uniprot id: C6WSY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

583345:MMOL RS00495
gene id: 583345:MMOL_RS00495
uniprot id: C6WYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

583345:MMOL RS08295
gene id: 583345:MMOL_RS08295
uniprot id: C6WX91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

583345:MMOL RS08505
gene id: 583345:MMOL_RS08505
uniprot id: C6WXD3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

583345:MMOL RS10185
gene id: 583345:MMOL_RS10185
uniprot id: C6WYJ2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS08750
gene id: 583345:MMOL_RS08750
uniprot id: C6WXI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

583345:MMOL RS03785
gene id: 583345:MMOL_RS03785
uniprot id: C6WUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

583345:MMOL RS09190
gene id: 583345:MMOL_RS09190
uniprot id: C6WXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

583345:MMOL RS10330
gene id: 583345:MMOL_RS10330
uniprot id: C6WYZ2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

583345:MMOL RS08085
gene id: 583345:MMOL_RS08085
uniprot id: C6WX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

583345:MMOL RS11410
gene id: 583345:MMOL_RS11410
uniprot id: C6WT96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

583345:MMOL RS02070
gene id: 583345:MMOL_RS02070
uniprot id: C6WTJ3
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

583345:MMOL RS03005
gene id: 583345:MMOL_RS03005
uniprot id: C6WUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

583345:MMOL RS11550
gene id: 583345:MMOL_RS11550
uniprot id: C6WTP6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

583345:MMOL RS08930
gene id: 583345:MMOL_RS08930
uniprot id: C6WXL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

583345:MMOL RS00725
gene id: 583345:MMOL_RS00725
uniprot id: C6WYT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS00135
gene id: 583345:MMOL_RS00135
uniprot id: C6WY42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS11140
gene id: 583345:MMOL_RS11140
uniprot id: C6WT42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

583345:MMOL RS02365
gene id: 583345:MMOL_RS02365
uniprot id: C6WTX7
names: Similarity
messages: Belongs to the pirin family.

583345:MMOL RS05005
gene id: 583345:MMOL_RS05005
uniprot id: C6WVE5
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04550
gene id: 583345:MMOL_RS04550
uniprot id: C6WV54
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

583345:MMOL RS03525
gene id: 583345:MMOL_RS03525
uniprot id: C6WUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS11320
gene id: 583345:MMOL_RS11320
uniprot id: C6WT78
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

583345:MMOL RS07685
gene id: 583345:MMOL_RS07685
uniprot id: C6WWX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583345:MMOL RS04035
gene id: 583345:MMOL_RS04035
uniprot id: C6WUV2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

583345:MMOL RS11315
gene id: 583345:MMOL_RS11315
uniprot id: C6WT77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

583345:MMOL RS07380
gene id: 583345:MMOL_RS07380
uniprot id: C6WWR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

583345:MMOL RS01925
gene id: 583345:MMOL_RS01925
uniprot id: C6WTG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

583345:MMOL RS04590
gene id: 583345:MMOL_RS04590
uniprot id: C6WV62
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

583345:MMOL RS07500
gene id: 583345:MMOL_RS07500
uniprot id: C6WWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

583345:MMOL RS09850
gene id: 583345:MMOL_RS09850
uniprot id: C6WYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

583345:MMOL RS11420
gene id: 583345:MMOL_RS11420
uniprot id: C6WT98
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

583345:MMOL RS08195
gene id: 583345:MMOL_RS08195
uniprot id: C6WX70
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

583345:MMOL RS00680
gene id: 583345:MMOL_RS00680
uniprot id: C6WYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

583345:MMOL RS05875
gene id: 583345:MMOL_RS05875
uniprot id: C6WVW6
names: Similarity
messages: Belongs to the skp family.

583345:MMOL RS10860
gene id: 583345:MMOL_RS10860
uniprot id: C6WZA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

583345:MMOL RS04805
gene id: 583345:MMOL_RS04805
uniprot id: C6WVA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

583345:MMOL RS03845
gene id: 583345:MMOL_RS03845
uniprot id: C6WUR8
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

583345:MMOL RS06350
gene id: 583345:MMOL_RS06350
uniprot id: C6WW57
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

583345:MMOL RS11575
gene id: 583345:MMOL_RS11575
uniprot id: C6WTQ1
names: Similarity
messages: Belongs to the P(II) protein family.

583345:MMOL RS08395
gene id: 583345:MMOL_RS08395
uniprot id: C6WXB1
names: Similarity
messages: Belongs to the CmpA/NrtA family.

583345:MMOL RS04370
gene id: 583345:MMOL_RS04370
uniprot id: C6WV18
names: Similarity
messages: Belongs to the FwdC/FmdC family.

583345:MMOL RS00140
gene id: 583345:MMOL_RS00140
uniprot id: C6WY43
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

583345:MMOL RS00010
gene id: 583345:MMOL_RS00010
uniprot id: C6WY16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

583345:MMOL RS09265
gene id: 583345:MMOL_RS09265
uniprot id: C6WXT4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

583345:MMOL RS06610
gene id: 583345:MMOL_RS06610
uniprot id: C6WWB0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

583345:MMOL RS08310
gene id: 583345:MMOL_RS08310
uniprot id: C6WX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

583345:MMOL RS01635
gene id: 583345:MMOL_RS01635
uniprot id: C6WSZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

583345:MMOL RS08575
gene id: 583345:MMOL_RS08575
uniprot id: C6WXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS09915
gene id: 583345:MMOL_RS09915
uniprot id: C6WYD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583345:MMOL RS11265
gene id: 583345:MMOL_RS11265
uniprot id: C6WT67
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

583345:MMOL RS06025
gene id: 583345:MMOL_RS06025
uniprot id: C6WVZ5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583345:MMOL RS03290
gene id: 583345:MMOL_RS03290
uniprot id: C6WUG1
names: Similarity
messages: Belongs to the UPF0434 family.

583345:MMOL RS05815
gene id: 583345:MMOL_RS05815
uniprot id: C6WVV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

583345:MMOL RS01835
gene id: 583345:MMOL_RS01835
uniprot id: C6WTE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

583345:MMOL RS08560
gene id: 583345:MMOL_RS08560
uniprot id: C6WXE4
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04710
gene id: 583345:MMOL_RS04710
uniprot id: C6WV86
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

583345:MMOL RS06480
gene id: 583345:MMOL_RS06480
uniprot id: C6WW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

583345:MMOL RS10040
gene id: 583345:MMOL_RS10040
uniprot id: C6WYG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

583345:MMOL RS01460
gene id: 583345:MMOL_RS01460
uniprot id: C6WSV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

583345:MMOL RS04815
gene id: 583345:MMOL_RS04815
uniprot id: C6WVA7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

583345:MMOL RS11385
gene id: 583345:MMOL_RS11385
uniprot id: C6WT91
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

583345:MMOL RS09095
gene id: 583345:MMOL_RS09095
uniprot id: C6WXQ0
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS01495
gene id: 583345:MMOL_RS01495
uniprot id: C6WSW2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

583345:MMOL RS06930
gene id: 583345:MMOL_RS06930
uniprot id: C6WWH0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

583345:MMOL RS09970
gene id: 583345:MMOL_RS09970
uniprot id: C6WYF0
names: Similarity
messages: Belongs to the UPF0276 family.

583345:MMOL RS10725
gene id: 583345:MMOL_RS10725
uniprot id: C6WZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS05790
gene id: 583345:MMOL_RS05790
uniprot id: C6WVU9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

583345:MMOL RS08865
gene id: 583345:MMOL_RS08865
uniprot id: C6WXK5
names: Similarity
messages: Belongs to the peptidase M16 family.

583345:MMOL RS03935
gene id: 583345:MMOL_RS03935
uniprot id: C6WUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

583345:MMOL RS11340
gene id: 583345:MMOL_RS11340
uniprot id: C6WT82
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

583345:MMOL RS04575
gene id: 583345:MMOL_RS04575
uniprot id: C6WV59
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

583345:MMOL RS01170
gene id: 583345:MMOL_RS01170
uniprot id: C6WSP7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

583345:MMOL RS04830
gene id: 583345:MMOL_RS04830
uniprot id: C6WVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

583345:MMOL RS08260
gene id: 583345:MMOL_RS08260
uniprot id: C6WX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

583345:MMOL RS08645
gene id: 583345:MMOL_RS08645
uniprot id: C6WXG1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

583345:MMOL RS10930
gene id: 583345:MMOL_RS10930
uniprot id: C6WT01
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

583345:MMOL RS01785
gene id: 583345:MMOL_RS01785
uniprot id: C6WTD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

583345:MMOL RS11430
gene id: 583345:MMOL_RS11430
uniprot id: C6WTA0
names: Similarity
messages: Belongs to the UPF0250 family.

583345:MMOL RS00900
gene id: 583345:MMOL_RS00900
uniprot id: C6WYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

583345:MMOL RS01895
gene id: 583345:MMOL_RS01895
uniprot id: C6WTF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

583345:MMOL RS05030
gene id: 583345:MMOL_RS05030
uniprot id: C6WVF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS09710
gene id: 583345:MMOL_RS09710
uniprot id: C6WY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS09655
gene id: 583345:MMOL_RS09655
uniprot id: C6WY10
names: Similarity
messages: Belongs to the aspartokinase family.

583345:MMOL RS07660
gene id: 583345:MMOL_RS07660
uniprot id: C6WWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

583345:MMOL RS06425
gene id: 583345:MMOL_RS06425
uniprot id: C6WW73
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

583345:MMOL RS05185
gene id: 583345:MMOL_RS05185
uniprot id: C6WVI2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

583345:MMOL RS11680
gene id: 583345:MMOL_RS11680
uniprot id: C6WTS2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01530
gene id: 583345:MMOL_RS01530
uniprot id: C6WSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS01945
gene id: 583345:MMOL_RS01945
uniprot id: C6WTG8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01865
gene id: 583345:MMOL_RS01865
uniprot id: C6WTF1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

583345:MMOL RS01720
gene id: 583345:MMOL_RS01720
uniprot id: C6WTC2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

583345:MMOL RS08335
gene id: 583345:MMOL_RS08335
uniprot id: C6WX99
names: Similarity
messages: Belongs to the UPF0178 family.

583345:MMOL RS11050
gene id: 583345:MMOL_RS11050
uniprot id: C6WT25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

583345:MMOL RS08355
gene id: 583345:MMOL_RS08355
uniprot id: C6WXA3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

583345:MMOL RS11000
gene id: 583345:MMOL_RS11000
uniprot id: C6WT15
names: Similarity
messages: Belongs to the TrpC family.

583345:MMOL RS03805
gene id: 583345:MMOL_RS03805
uniprot id: C6WUQ9
names: Similarity
messages: Belongs to the PrpD family.

583345:MMOL RS07765
gene id: 583345:MMOL_RS07765
uniprot id: C6WWY7
names: Similarity
messages: Belongs to the threonine synthase family.

583345:MMOL RS02870
gene id: 583345:MMOL_RS02870
uniprot id: C6WU77
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

583345:MMOL RS09595
gene id: 583345:MMOL_RS09595
uniprot id: C6WXZ8
names: Similarity
messages: Belongs to the peptidase U62 family.

583345:MMOL RS04845
gene id: 583345:MMOL_RS04845
uniprot id: C6WVB3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

583345:MMOL RS09205
gene id: 583345:MMOL_RS09205
uniprot id: C6WXS2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

583345:MMOL RS04280
gene id: 583345:MMOL_RS04280
uniprot id: C6WV02
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

583345:MMOL RS08040
gene id: 583345:MMOL_RS08040
uniprot id: C6WX41
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

583345:MMOL RS10195
gene id: 583345:MMOL_RS10195
uniprot id: C6WYJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

583345:MMOL RS02795
gene id: 583345:MMOL_RS02795
uniprot id: C6WU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

583345:MMOL RS05785
gene id: 583345:MMOL_RS05785
uniprot id: C6WVU8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

583345:MMOL RS10275
gene id: 583345:MMOL_RS10275
uniprot id: C6WYL0
names: Similarity
messages: Belongs to the thioredoxin family.

583345:MMOL RS04180
gene id: 583345:MMOL_RS04180
uniprot id: C6WUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

583345:MMOL RS03115
gene id: 583345:MMOL_RS03115
uniprot id: C6WUC6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

583345:MMOL RS01825
gene id: 583345:MMOL_RS01825
uniprot id: C6WTE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

583345:MMOL RS05775
gene id: 583345:MMOL_RS05775
uniprot id: C6WVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

583345:MMOL RS03590
gene id: 583345:MMOL_RS03590
uniprot id: C6WUL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

583345:MMOL RS02240
gene id: 583345:MMOL_RS02240
uniprot id: C6WTM8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

583345:MMOL RS05035
gene id: 583345:MMOL_RS05035
uniprot id: C6WVF1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

583345:MMOL RS00905
gene id: 583345:MMOL_RS00905
uniprot id: C6WYW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583345:MMOL RS05160
gene id: 583345:MMOL_RS05160
uniprot id: C6WVH7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

583345:MMOL RS02960
gene id: 583345:MMOL_RS02960
uniprot id: C6WU95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

583345:MMOL RS01960
gene id: 583345:MMOL_RS01960
uniprot id: C6WTH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

583345:MMOL RS10790
gene id: 583345:MMOL_RS10790
uniprot id: C6WZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

583345:MMOL RS08675
gene id: 583345:MMOL_RS08675
uniprot id: C6WXG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS10020
gene id: 583345:MMOL_RS10020
uniprot id: C6WYG0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

583345:MMOL RS04770
gene id: 583345:MMOL_RS04770
uniprot id: C6WV98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

583345:MMOL RS08455
gene id: 583345:MMOL_RS08455
uniprot id: C6WXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS10535
gene id: 583345:MMOL_RS10535
uniprot id: C6WZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583345:MMOL RS04930
gene id: 583345:MMOL_RS04930
uniprot id: C6WVD0
names: Similarity
messages: Belongs to the UPF0234 family.

583345:MMOL RS00765
gene id: 583345:MMOL_RS00765
uniprot id: C6WYU1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

583345:MMOL RS00445
gene id: 583345:MMOL_RS00445
uniprot id: C6WYM7
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS00485
gene id: 583345:MMOL_RS00485
uniprot id: C6WYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583345:MMOL RS07345
gene id: 583345:MMOL_RS07345
uniprot id: C6WWQ4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

583345:MMOL RS05890
gene id: 583345:MMOL_RS05890
uniprot id: C6WVW9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS06965
gene id: 583345:MMOL_RS06965
uniprot id: C6WWH7
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

583345:MMOL RS05385
gene id: 583345:MMOL_RS05385
uniprot id: C6WVM1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.

583345:MMOL RS00835
gene id: 583345:MMOL_RS00835
uniprot id: C6WYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

583345:MMOL RS03185
gene id: 583345:MMOL_RS03185
uniprot id: C6WUE0
names: Similarity
messages: Belongs to the YggT family.

583345:MMOL RS05070
gene id: 583345:MMOL_RS05070
uniprot id: C6WVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

583345:MMOL RS11005
gene id: 583345:MMOL_RS11005
uniprot id: C6WT16
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

583345:MMOL RS05755
gene id: 583345:MMOL_RS05755
uniprot id: C6WVU2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

583345:MMOL RS03775
gene id: 583345:MMOL_RS03775
uniprot id: C6WUQ3
names: Similarity
messages: Belongs to the WrbA family.

583345:MMOL RS07295
gene id: 583345:MMOL_RS07295
uniprot id: C6WWP4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

583345:MMOL RS07080
gene id: 583345:MMOL_RS07080
uniprot id: C6WWK1
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS02405
gene id: 583345:MMOL_RS02405
uniprot id: C6WTY5
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS01725
gene id: 583345:MMOL_RS01725
uniprot id: C6WTC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

583345:MMOL RS05175
gene id: 583345:MMOL_RS05175
uniprot id: C6WVI0
names: Similarity
messages: Belongs to the peptidase S16 family.

583345:MMOL RS01055
gene id: 583345:MMOL_RS01055
uniprot id: C6WSM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

583345:MMOL RS02190
gene id: 583345:MMOL_RS02190
uniprot id: C6WTL9
names: Similarity
messages: Belongs to the YjdM family.

583345:MMOL RS08690
gene id: 583345:MMOL_RS08690
uniprot id: C6WXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

583345:MMOL RS04980
gene id: 583345:MMOL_RS04980
uniprot id: C6WVE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

583345:MMOL RS10520
gene id: 583345:MMOL_RS10520
uniprot id: C6WZ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

583345:MMOL RS03170
gene id: 583345:MMOL_RS03170
uniprot id: C6WUD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

583345:MMOL RS00940
gene id: 583345:MMOL_RS00940
uniprot id: C6WYX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

583345:MMOL RS02600
gene id: 583345:MMOL_RS02600
uniprot id: C6WU23
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

583345:MMOL RS06835
gene id: 583345:MMOL_RS06835
uniprot id: C6WWF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

583345:MMOL RS10085
gene id: 583345:MMOL_RS10085
uniprot id: C6WYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

583345:MMOL RS05080
gene id: 583345:MMOL_RS05080
uniprot id: C6WVG1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

583345:MMOL RS07700
gene id: 583345:MMOL_RS07700
uniprot id: C6WWX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

583345:MMOL RS03230
gene id: 583345:MMOL_RS03230
uniprot id: C6WUE9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

583345:MMOL RS07160
gene id: 583345:MMOL_RS07160
uniprot id: C6WWL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

583345:MMOL RS00015
gene id: 583345:MMOL_RS00015
uniprot id: C6WY17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

583345:MMOL RS06940
gene id: 583345:MMOL_RS06940
uniprot id: C6WWH2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

583345:MMOL RS09675
gene id: 583345:MMOL_RS09675
uniprot id: C6WY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS07575
gene id: 583345:MMOL_RS07575
uniprot id: C6WWU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

583345:MMOL RS07280
gene id: 583345:MMOL_RS07280
uniprot id: C6WWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

583345:MMOL RS01800
gene id: 583345:MMOL_RS01800
uniprot id: C6WTD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

583345:MMOL RS03370
gene id: 583345:MMOL_RS03370
uniprot id: C6WUH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS08810
gene id: 583345:MMOL_RS08810
uniprot id: C6WXJ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

583345:MMOL RS05810
gene id: 583345:MMOL_RS05810
uniprot id: C6WVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

583345:MMOL RS08275
gene id: 583345:MMOL_RS08275
uniprot id: C6WX87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

583345:MMOL RS03565
gene id: 583345:MMOL_RS03565
uniprot id: C6WUL0
names: Similarity
messages: Belongs to the ArsC family.

583345:MMOL RS07520
gene id: 583345:MMOL_RS07520
uniprot id: C6WWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

583345:MMOL RS04115
gene id: 583345:MMOL_RS04115
uniprot id: C6WUW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

583345:MMOL RS04505
gene id: 583345:MMOL_RS04505
uniprot id: C6WV46
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS05375
gene id: 583345:MMOL_RS05375
uniprot id: C6WVL9
names: Similarity
messages: Belongs to the SCO1/2 family.

583345:MMOL RS05335
gene id: 583345:MMOL_RS05335
uniprot id: C6WVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

583345:MMOL RS09400
gene id: 583345:MMOL_RS09400
uniprot id: C6WXV9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

583345:MMOL RS00045
gene id: 583345:MMOL_RS00045
uniprot id: C6WY23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS03190
gene id: 583345:MMOL_RS03190
uniprot id: C6WUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

583345:MMOL RS03235
gene id: 583345:MMOL_RS03235
uniprot id: C6WUF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

583345:MMOL RS01095
gene id: 583345:MMOL_RS01095
uniprot id: C6WSN5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS02040
gene id: 583345:MMOL_RS02040
uniprot id: C6WTI7
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS01715
gene id: 583345:MMOL_RS01715
uniprot id: C6WTC1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

583345:MMOL RS07705
gene id: 583345:MMOL_RS07705
uniprot id: C6WWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

583345:MMOL RS01640
gene id: 583345:MMOL_RS01640
uniprot id: C6WSZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

583345:MMOL RS10360
gene id: 583345:MMOL_RS10360
uniprot id: C6WYZ8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

583345:MMOL RS08805
gene id: 583345:MMOL_RS08805
uniprot id: C6WXJ3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

583345:MMOL RS06810
gene id: 583345:MMOL_RS06810
uniprot id: C6WWE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

583345:MMOL RS03560
gene id: 583345:MMOL_RS03560
uniprot id: C6WUK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

583345:MMOL RS05505
gene id: 583345:MMOL_RS05505
uniprot id: C6WVP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

583345:MMOL RS02905
gene id: 583345:MMOL_RS02905
uniprot id: C6WU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

583345:MMOL RS10470
gene id: 583345:MMOL_RS10470
uniprot id: C6WZ22
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

583345:MMOL RS01380
gene id: 583345:MMOL_RS01380
uniprot id: C6WST9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

583345:MMOL RS03450
gene id: 583345:MMOL_RS03450
uniprot id: C6WUI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

583345:MMOL RS06360
gene id: 583345:MMOL_RS06360
uniprot id: C6WW59
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

583345:MMOL RS04885
gene id: 583345:MMOL_RS04885
uniprot id: C6WVC1
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

583345:MMOL RS10570
gene id: 583345:MMOL_RS10570
uniprot id: C6WZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

583345:MMOL RS03055
gene id: 583345:MMOL_RS03055
uniprot id: C6WUB4
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

583345:MMOL RS02765
gene id: 583345:MMOL_RS02765
uniprot id: C6WU56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

583345:MMOL RS03810
gene id: 583345:MMOL_RS03810
uniprot id: C6WUR0
names: Similarity
messages: Belongs to the citrate synthase family.

583345:MMOL RS04660
gene id: 583345:MMOL_RS04660
uniprot id: C6WV76
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

583345:MMOL RS09480
gene id: 583345:MMOL_RS09480
uniprot id: C6WXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

583345:MMOL RS10740
gene id: 583345:MMOL_RS10740
uniprot id: C6WZ78
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

583345:MMOL RS11775
gene id: 583345:MMOL_RS11775
uniprot id: C6WTT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

583345:MMOL RS08165
gene id: 583345:MMOL_RS08165
uniprot id: C6WX64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

583345:MMOL RS03015
gene id: 583345:MMOL_RS03015
uniprot id: C6WUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

583345:MMOL RS10485
gene id: 583345:MMOL_RS10485
uniprot id: C6WZ25
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

583345:MMOL RS08665
gene id: 583345:MMOL_RS08665
uniprot id: C6WXG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS01040
gene id: 583345:MMOL_RS01040
uniprot id: C6WSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

583345:MMOL RS08030
gene id: 583345:MMOL_RS08030
uniprot id: C6WX39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583345:MMOL RS02050
gene id: 583345:MMOL_RS02050
uniprot id: C6WTI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS08555
gene id: 583345:MMOL_RS08555
uniprot id: C6WXE3
names: Similarity
messages: Belongs to the UPF0111 family.

583345:MMOL RS05720
gene id: 583345:MMOL_RS05720
uniprot id: C6WVT6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

583345:MMOL RS10290
gene id: 583345:MMOL_RS10290
uniprot id: C6WYL3
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS08270
gene id: 583345:MMOL_RS08270
uniprot id: C6WX86
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

583345:MMOL RS07385
gene id: 583345:MMOL_RS07385
uniprot id: C6WWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

583345:MMOL RS00080
gene id: 583345:MMOL_RS00080
uniprot id: C6WY30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS03020
gene id: 583345:MMOL_RS03020
uniprot id: C6WUA7
names: Subcellular Location Annotation
messages: Cytoplasm

583345:MMOL RS04610
gene id: 583345:MMOL_RS04610
uniprot id: C6WV66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

583345:MMOL RS02075
gene id: 583345:MMOL_RS02075
uniprot id: C6WTJ4
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS06340
gene id: 583345:MMOL_RS06340
uniprot id: C6WW55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

583345:MMOL RS11020
gene id: 583345:MMOL_RS11020
uniprot id: C6WT19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583345:MMOL RS00020
gene id: 583345:MMOL_RS00020
uniprot id: C6WY18
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

583345:MMOL RS11625
gene id: 583345:MMOL_RS11625
uniprot id: C6WTR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583345:MMOL RS04250
gene id: 583345:MMOL_RS04250
uniprot id: C6WUZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583345:MMOL RS09565
gene id: 583345:MMOL_RS09565
uniprot id: C6WXZ2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

583345:MMOL RS04725
gene id: 583345:MMOL_RS04725
uniprot id: C6WV89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

583345:MMOL RS02620
gene id: 583345:MMOL_RS02620
uniprot id: C6WU27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

583345:MMOL RS08640
gene id: 583345:MMOL_RS08640
uniprot id: C6WXG0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS00915
gene id: 583345:MMOL_RS00915
uniprot id: C6WYX1
names: Similarity
messages: Belongs to the RutC family.

583345:MMOL RS08515
gene id: 583345:MMOL_RS08515
uniprot id: C6WXD5
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS03695
gene id: 583345:MMOL_RS03695
uniprot id: C6WUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

583345:MMOL RS07290
gene id: 583345:MMOL_RS07290
uniprot id: C6WWP3
names: Similarity
messages: Belongs to the Dps family.

583345:MMOL RS08605
gene id: 583345:MMOL_RS08605
uniprot id: C6WXF3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

583345:MMOL RS03880
gene id: 583345:MMOL_RS03880
uniprot id: C6WUS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

583345:MMOL RS07805
gene id: 583345:MMOL_RS07805
uniprot id: C6WWZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

583345:MMOL RS05200
gene id: 583345:MMOL_RS05200
uniprot id: C6WVI5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS08950
gene id: 583345:MMOL_RS08950
uniprot id: C6WXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

583345:MMOL RS09035
gene id: 583345:MMOL_RS09035
uniprot id: C6WXN8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

583345:MMOL RS10250
gene id: 583345:MMOL_RS10250
uniprot id: C6WYK5
names: Similarity
messages: Belongs to the UPF0102 family.

583345:MMOL RS06920
gene id: 583345:MMOL_RS06920
uniprot id: C6WWG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

583345:MMOL RS10455
gene id: 583345:MMOL_RS10455
uniprot id: C6WZ19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

583345:MMOL RS10625
gene id: 583345:MMOL_RS10625
uniprot id: C6WZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS12185
gene id: 583345:MMOL_RS12185
uniprot id: C6WVI9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

583345:MMOL RS03340
gene id: 583345:MMOL_RS03340
uniprot id: C6WUG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

583345:MMOL RS06155
gene id: 583345:MMOL_RS06155
uniprot id: C6WW19
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS08215
gene id: 583345:MMOL_RS08215
uniprot id: C6WX74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

583345:MMOL RS07730
gene id: 583345:MMOL_RS07730
uniprot id: C6WWY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

583345:MMOL RS11705
gene id: 583345:MMOL_RS11705
uniprot id: C6WTS6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583345:MMOL RS06200
gene id: 583345:MMOL_RS06200
uniprot id: C6WW28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS01850
gene id: 583345:MMOL_RS01850
uniprot id: C6WTE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

583345:MMOL RS01620
gene id: 583345:MMOL_RS01620
uniprot id: C6WSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

583345:MMOL RS10280
gene id: 583345:MMOL_RS10280
uniprot id: C6WYL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS02625
gene id: 583345:MMOL_RS02625
uniprot id: C6WU28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

583345:MMOL RS10380
gene id: 583345:MMOL_RS10380
uniprot id: C6WZ02
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

583345:MMOL RS03570
gene id: 583345:MMOL_RS03570
uniprot id: C6WUL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

583345:MMOL RS04455
gene id: 583345:MMOL_RS04455
uniprot id: C6WV35
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583345:MMOL RS06575
gene id: 583345:MMOL_RS06575
uniprot id: C6WWA3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

583345:MMOL RS01955
gene id: 583345:MMOL_RS01955
uniprot id: C6WTH0
names: Similarity
messages: Belongs to the UPF0758 family.

583345:MMOL RS04040
gene id: 583345:MMOL_RS04040
uniprot id: C6WUV3
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

583345:MMOL RS00720
gene id: 583345:MMOL_RS00720
uniprot id: C6WYT2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

583345:MMOL RS05130
gene id: 583345:MMOL_RS05130
uniprot id: C6WVH1
names: Similarity
messages: Belongs to the IMPACT family.

583345:MMOL RS02690
gene id: 583345:MMOL_RS02690
uniprot id: C6WU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

583345:MMOL RS00705
gene id: 583345:MMOL_RS00705
uniprot id: C6WYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS03995
gene id: 583345:MMOL_RS03995
uniprot id: C6WUU5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583345:MMOL RS06310
gene id: 583345:MMOL_RS06310
uniprot id: C6WW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

583345:MMOL RS03855
gene id: 583345:MMOL_RS03855
uniprot id: C6WUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS03275
gene id: 583345:MMOL_RS03275
uniprot id: C6WUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583345:MMOL RS09460
gene id: 583345:MMOL_RS09460
uniprot id: C6WXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS03720
gene id: 583345:MMOL_RS03720
uniprot id: C6WUP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS07150
gene id: 583345:MMOL_RS07150
uniprot id: C6WWL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

583345:MMOL RS11750
gene id: 583345:MMOL_RS11750
uniprot id: C6WTT4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

583345:MMOL RS05510
gene id: 583345:MMOL_RS05510
uniprot id: C6WVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

583345:MMOL RS04585
gene id: 583345:MMOL_RS04585
uniprot id: C6WV61
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS11120
gene id: 583345:MMOL_RS11120
uniprot id: C6WT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS10595
gene id: 583345:MMOL_RS10595
uniprot id: C6WZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

583345:MMOL RS06870
gene id: 583345:MMOL_RS06870
uniprot id: C6WWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

583345:MMOL RS05675
gene id: 583345:MMOL_RS05675
uniprot id: C6WVS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS09800
gene id: 583345:MMOL_RS09800
uniprot id: C6WYB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

583345:MMOL RS05110
gene id: 583345:MMOL_RS05110
uniprot id: C6WVG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS00945
gene id: 583345:MMOL_RS00945
uniprot id: C6WYX7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

583345:MMOL RS11295
gene id: 583345:MMOL_RS11295
uniprot id: C6WT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

583345:MMOL RS01915
gene id: 583345:MMOL_RS01915
uniprot id: C6WTG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS01670
gene id: 583345:MMOL_RS01670
uniprot id: C6WTB7
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

583345:MMOL RS01085
gene id: 583345:MMOL_RS01085
uniprot id: C6WSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

583345:MMOL RS11555
gene id: 583345:MMOL_RS11555
uniprot id: C6WTP7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

583345:MMOL RS08140
gene id: 583345:MMOL_RS08140
uniprot id: C6WX60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583345:MMOL RS03815
gene id: 583345:MMOL_RS03815
uniprot id: C6WUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

583345:MMOL RS04995
gene id: 583345:MMOL_RS04995
uniprot id: C6WVE3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

583345:MMOL RS04970
gene id: 583345:MMOL_RS04970
uniprot id: C6WVD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS02205
gene id: 583345:MMOL_RS02205
uniprot id: C6WTM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS04190
gene id: 583345:MMOL_RS04190
uniprot id: C6WUY3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

583345:MMOL RS02110
gene id: 583345:MMOL_RS02110
uniprot id: C6WTK2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

583345:MMOL RS04675
gene id: 583345:MMOL_RS04675
uniprot id: C6WV79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

583345:MMOL RS02045
gene id: 583345:MMOL_RS02045
uniprot id: C6WTI8
names: Similarity
messages: Belongs to the peptidase M18 family.

583345:MMOL RS05685
gene id: 583345:MMOL_RS05685
uniprot id: C6WVS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

583345:MMOL RS11475
gene id: 583345:MMOL_RS11475
uniprot id: C6WTA9
names: Similarity
messages: Belongs to the PilY1 family.

583345:MMOL RS05170
gene id: 583345:MMOL_RS05170
uniprot id: C6WVH9
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

583345:MMOL RS07645
gene id: 583345:MMOL_RS07645
uniprot id: C6WWW3
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

583345:MMOL RS00435
gene id: 583345:MMOL_RS00435
uniprot id: C6WYM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583345:MMOL RS02140
gene id: 583345:MMOL_RS02140
uniprot id: C6WTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

583345:MMOL RS01070
gene id: 583345:MMOL_RS01070
uniprot id: C6WSN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

583345:MMOL RS09295
gene id: 583345:MMOL_RS09295
uniprot id: C6WXT9
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS10765
gene id: 583345:MMOL_RS10765
uniprot id: C6WZ82
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

583345:MMOL RS04100
gene id: 583345:MMOL_RS04100
uniprot id: C6WUW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

583345:MMOL RS06770
gene id: 583345:MMOL_RS06770
uniprot id: C6WWD8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

583345:MMOL RS09910
gene id: 583345:MMOL_RS09910
uniprot id: C6WYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583345:MMOL RS05880
gene id: 583345:MMOL_RS05880
uniprot id: C6WVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

583345:MMOL RS04535
gene id: 583345:MMOL_RS04535
uniprot id: C6WV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

583345:MMOL RS08485
gene id: 583345:MMOL_RS08485
uniprot id: C6WXC9
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

583345:MMOL RS08845
gene id: 583345:MMOL_RS08845
uniprot id: C6WXK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

583345:MMOL RS10945
gene id: 583345:MMOL_RS10945
uniprot id: C6WT04
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

583345:MMOL RS06955
gene id: 583345:MMOL_RS06955
uniprot id: C6WWH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

583345:MMOL RS10010
gene id: 583345:MMOL_RS10010
uniprot id: C6WYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

583345:MMOL RS09220
gene id: 583345:MMOL_RS09220
uniprot id: C6WXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

583345:MMOL RS11660
gene id: 583345:MMOL_RS11660
uniprot id: C6WTR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS05135
gene id: 583345:MMOL_RS05135
uniprot id: C6WVH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583345:MMOL RS05980
gene id: 583345:MMOL_RS05980
uniprot id: C6WVY6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

583345:MMOL RS06435
gene id: 583345:MMOL_RS06435
uniprot id: C6WW75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

583345:MMOL RS06355
gene id: 583345:MMOL_RS06355
uniprot id: C6WW58
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

583345:MMOL RS03125
gene id: 583345:MMOL_RS03125
uniprot id: C6WUC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

583345:MMOL RS02295
gene id: 583345:MMOL_RS02295
uniprot id: C6WTW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

583345:MMOL RS01030
gene id: 583345:MMOL_RS01030
uniprot id: C6WSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

583345:MMOL RS04080
gene id: 583345:MMOL_RS04080
uniprot id: C6WUW1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

583345:MMOL RS07875
gene id: 583345:MMOL_RS07875
uniprot id: C6WX10
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

583345:MMOL RS02030
gene id: 583345:MMOL_RS02030
uniprot id: C6WTI5
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

583345:MMOL RS11865
gene id: 583345:MMOL_RS11865
uniprot id: C6WTV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

583345:MMOL RS04060
gene id: 583345:MMOL_RS04060
uniprot id: C6WUV7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

583345:MMOL RS07915
gene id: 583345:MMOL_RS07915
uniprot id: C6WX18
names: Similarity
messages: Belongs to the phosphohexose mutase family.

583345:MMOL RS05920
gene id: 583345:MMOL_RS05920
uniprot id: C6WVX5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

583345:MMOL RS06055
gene id: 583345:MMOL_RS06055
uniprot id: C6WVZ9
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS04940
gene id: 583345:MMOL_RS04940
uniprot id: C6WVD2
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

583345:MMOL RS09985
gene id: 583345:MMOL_RS09985
uniprot id: C6WYF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

583345:MMOL RS08910
gene id: 583345:MMOL_RS08910
uniprot id: C6WXL5
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS09420
gene id: 583345:MMOL_RS09420
uniprot id: C6WXW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

583345:MMOL RS03270
gene id: 583345:MMOL_RS03270
uniprot id: C6WUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583345:MMOL RS07890
gene id: 583345:MMOL_RS07890
uniprot id: C6WX13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

583345:MMOL RS10215
gene id: 583345:MMOL_RS10215
uniprot id: C6WYJ8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

583345:MMOL RS08755
gene id: 583345:MMOL_RS08755
uniprot id: C6WXI3
names: Similarity
messages: Belongs to the NodU/CmcH family.

583345:MMOL RS07755
gene id: 583345:MMOL_RS07755
uniprot id: C6WWY5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

583345:MMOL RS11670
gene id: 583345:MMOL_RS11670
uniprot id: C6WTS0
names: Similarity
messages: Belongs to the glutamate synthase family.

583345:MMOL RS11560
gene id: 583345:MMOL_RS11560
uniprot id: C6WTP8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

583345:MMOL RS02805
gene id: 583345:MMOL_RS02805
uniprot id: C6WU64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS06655
gene id: 583345:MMOL_RS06655
uniprot id: C6WWB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

583345:MMOL RS00810
gene id: 583345:MMOL_RS00810
uniprot id: C6WYV0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

583345:MMOL RS03120
gene id: 583345:MMOL_RS03120
uniprot id: C6WUC7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS09285
gene id: 583345:MMOL_RS09285
uniprot id: C6WXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

583345:MMOL RS01365
gene id: 583345:MMOL_RS01365
uniprot id: C6WST6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS08465
gene id: 583345:MMOL_RS08465
uniprot id: C6WXC5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

583345:MMOL RS03060
gene id: 583345:MMOL_RS03060
uniprot id: C6WUB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

583345:MMOL RS05050
gene id: 583345:MMOL_RS05050
uniprot id: C6WVF5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

583345:MMOL RS08565
gene id: 583345:MMOL_RS08565
uniprot id: C6WXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

583345:MMOL RS08020
gene id: 583345:MMOL_RS08020
uniprot id: C6WX37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

583345:MMOL RS06705
gene id: 583345:MMOL_RS06705
uniprot id: C6WWC7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

583345:MMOL RS08340
gene id: 583345:MMOL_RS08340
uniprot id: C6WXA0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

583345:MMOL RS06515
gene id: 583345:MMOL_RS06515
uniprot id: C6WW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

583345:MMOL RS00930
gene id: 583345:MMOL_RS00930
uniprot id: C6WYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

583345:MMOL RS01580
gene id: 583345:MMOL_RS01580
uniprot id: C6WSX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

583345:MMOL RS04925
gene id: 583345:MMOL_RS04925
uniprot id: C6WVC9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

583345:MMOL RS05040
gene id: 583345:MMOL_RS05040
uniprot id: C6WVF2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

583345:MMOL RS02705
gene id: 583345:MMOL_RS02705
uniprot id: C6WU44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

583345:MMOL RS05955
gene id: 583345:MMOL_RS05955
uniprot id: C6WVY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

583345:MMOL RS09490
gene id: 583345:MMOL_RS09490
uniprot id: C6WXX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583345:MMOL RS05915
gene id: 583345:MMOL_RS05915
uniprot id: C6WVX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS11730
gene id: 583345:MMOL_RS11730
uniprot id: C6WTT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

583345:MMOL RS04720
gene id: 583345:MMOL_RS04720
uniprot id: C6WV88
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

583345:MMOL RS10130
gene id: 583345:MMOL_RS10130
uniprot id: C6WYI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS05095
gene id: 583345:MMOL_RS05095
uniprot id: C6WVG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

583345:MMOL RS11870
gene id: 583345:MMOL_RS11870
uniprot id: C6WTV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

583345:MMOL RS09590
gene id: 583345:MMOL_RS09590
uniprot id: C6WXZ7
names: Similarity
messages: Belongs to the MlaA family.

583345:MMOL RS01795
gene id: 583345:MMOL_RS01795
uniprot id: C6WTD7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

583345:MMOL RS09530
gene id: 583345:MMOL_RS09530
uniprot id: C6WXY5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

583345:MMOL RS09885
gene id: 583345:MMOL_RS09885
uniprot id: C6WYD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

583345:MMOL RS02915
gene id: 583345:MMOL_RS02915
uniprot id: C6WU86
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

583345:MMOL RS01455
gene id: 583345:MMOL_RS01455
uniprot id: C6WSV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

583345:MMOL RS05780
gene id: 583345:MMOL_RS05780
uniprot id: C6WVU7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

583345:MMOL RS02085
gene id: 583345:MMOL_RS02085
uniprot id: C6WTJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

583345:MMOL RS05395
gene id: 583345:MMOL_RS05395
uniprot id: C6WVM3
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS02180
gene id: 583345:MMOL_RS02180
uniprot id: C6WTL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

583345:MMOL RS04975
gene id: 583345:MMOL_RS04975
uniprot id: C6WVD9
names: Similarity
messages: Belongs to the TrpF family.

583345:MMOL RS05215
gene id: 583345:MMOL_RS05215
uniprot id: C6WVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS03265
gene id: 583345:MMOL_RS03265
uniprot id: C6WUF6
names: Subcellular Location Annotation
messages: Cell inner membrane

583345:MMOL RS05910
gene id: 583345:MMOL_RS05910
uniprot id: C6WVX3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01470
gene id: 583345:MMOL_RS01470
uniprot id: C6WSV7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

583345:MMOL RS01940
gene id: 583345:MMOL_RS01940
uniprot id: C6WTG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS02595
gene id: 583345:MMOL_RS02595
uniprot id: C6WU22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

583345:MMOL RS06800
gene id: 583345:MMOL_RS06800
uniprot id: C6WWE4
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

583345:MMOL RS07925
gene id: 583345:MMOL_RS07925
uniprot id: C6WX20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

583345:MMOL RS08370
gene id: 583345:MMOL_RS08370
uniprot id: C6WXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

583345:MMOL RS03580
gene id: 583345:MMOL_RS03580
uniprot id: C6WUL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

583345:MMOL RS03465
gene id: 583345:MMOL_RS03465
uniprot id: C6WUJ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS02575
gene id: 583345:MMOL_RS02575
uniprot id: C6WU18
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

583345:MMOL RS01585
gene id: 583345:MMOL_RS01585
uniprot id: C6WSY0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

583345:MMOL RS03130
gene id: 583345:MMOL_RS03130
uniprot id: C6WUC9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

583345:MMOL RS01245
gene id: 583345:MMOL_RS01245
uniprot id: C6WSR2
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS03350
gene id: 583345:MMOL_RS03350
uniprot id: C6WUG7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

583345:MMOL RS00970
gene id: 583345:MMOL_RS00970
uniprot id: C6WYY2
names: Similarity
messages: Belongs to the citrate synthase family.

583345:MMOL RS09830
gene id: 583345:MMOL_RS09830
uniprot id: C6WYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

583345:MMOL RS07735
gene id: 583345:MMOL_RS07735
uniprot id: C6WWY1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

583345:MMOL RS01400
gene id: 583345:MMOL_RS01400
uniprot id: C6WSU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583345:MMOL RS07270
gene id: 583345:MMOL_RS07270
uniprot id: C6WWN9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS04365
gene id: 583345:MMOL_RS04365
uniprot id: C6WV17
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

583345:MMOL RS01215
gene id: 583345:MMOL_RS01215
uniprot id: C6WSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS02510
gene id: 583345:MMOL_RS02510
uniprot id: C6WU05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

583345:MMOL RS06015
gene id: 583345:MMOL_RS06015
uniprot id: C6WVZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

583345:MMOL RS02800
gene id: 583345:MMOL_RS02800
uniprot id: C6WU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

583345:MMOL RS10180
gene id: 583345:MMOL_RS10180
uniprot id: C6WYJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

583345:MMOL RS02065
gene id: 583345:MMOL_RS02065
uniprot id: C6WTJ2
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

583345:MMOL RS09870
gene id: 583345:MMOL_RS09870
uniprot id: C6WYD0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

583345:MMOL RS01250
gene id: 583345:MMOL_RS01250
uniprot id: C6WSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

583345:MMOL RS04480
gene id: 583345:MMOL_RS04480
uniprot id: C6WV40
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS00030
gene id: 583345:MMOL_RS00030
uniprot id: C6WY20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS03225
gene id: 583345:MMOL_RS03225
uniprot id: C6WUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

583345:MMOL RS01330
gene id: 583345:MMOL_RS01330
uniprot id: C6WST0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS05060
gene id: 583345:MMOL_RS05060
uniprot id: C6WVF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

583345:MMOL RS10135
gene id: 583345:MMOL_RS10135
uniprot id: C6WYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

583345:MMOL RS11590
gene id: 583345:MMOL_RS11590
uniprot id: C6WTQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

583345:MMOL RS09540
gene id: 583345:MMOL_RS09540
uniprot id: C6WXY7
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

583345:MMOL RS07655
gene id: 583345:MMOL_RS07655
uniprot id: C6WWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

583345:MMOL RS05295
gene id: 583345:MMOL_RS05295
uniprot id: C6WVK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

583345:MMOL RS07690
gene id: 583345:MMOL_RS07690
uniprot id: C6WWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

583345:MMOL RS01740
gene id: 583345:MMOL_RS01740
uniprot id: C6WTC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583345:MMOL RS08130
gene id: 583345:MMOL_RS08130
uniprot id: C6WX58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583345:MMOL RS06935
gene id: 583345:MMOL_RS06935
uniprot id: C6WWH1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

583345:MMOL RS03545
gene id: 583345:MMOL_RS03545
uniprot id: C6WUK6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

583345:MMOL RS09620
gene id: 583345:MMOL_RS09620
uniprot id: C6WY03
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

583345:MMOL RS04470
gene id: 583345:MMOL_RS04470
uniprot id: C6WV38
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

583345:MMOL RS06010
gene id: 583345:MMOL_RS06010
uniprot id: C6WVZ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

583345:MMOL RS08120
gene id: 583345:MMOL_RS08120
uniprot id: C6WX56
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

583345:MMOL RS01490
gene id: 583345:MMOL_RS01490
uniprot id: C6WSW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS07760
gene id: 583345:MMOL_RS07760
uniprot id: C6WWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS07320
gene id: 583345:MMOL_RS07320
uniprot id: C6WWP9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583345:MMOL RS03200
gene id: 583345:MMOL_RS03200
uniprot id: C6WUE3
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS06725
gene id: 583345:MMOL_RS06725
uniprot id: C6WWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

583345:MMOL RS05860
gene id: 583345:MMOL_RS05860
uniprot id: C6WVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

583345:MMOL RS10230
gene id: 583345:MMOL_RS10230
uniprot id: C6WYK1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS03400
gene id: 583345:MMOL_RS03400
uniprot id: C6WUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

583345:MMOL RS02275
gene id: 583345:MMOL_RS02275
uniprot id: C6WTN5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

583345:MMOL RS11395
gene id: 583345:MMOL_RS11395
uniprot id: C6WT93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

583345:MMOL RS11855
gene id: 583345:MMOL_RS11855
uniprot id: C6WTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

583345:MMOL RS11435
gene id: 583345:MMOL_RS11435
uniprot id: C6WTA1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

583345:MMOL RS08510
gene id: 583345:MMOL_RS08510
uniprot id: C6WXD4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

583345:MMOL RS02345
gene id: 583345:MMOL_RS02345
uniprot id: C6WTX3
names: Similarity
messages: Belongs to the peptidase S24 family.

583345:MMOL RS06420
gene id: 583345:MMOL_RS06420
uniprot id: C6WW72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

583345:MMOL RS10635
gene id: 583345:MMOL_RS10635
uniprot id: C6WZ55
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS11030
gene id: 583345:MMOL_RS11030
uniprot id: C6WT21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

583345:MMOL RS04870
gene id: 583345:MMOL_RS04870
uniprot id: C6WVB8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

583345:MMOL RS10560
gene id: 583345:MMOL_RS10560
uniprot id: C6WZ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

583345:MMOL RS02700
gene id: 583345:MMOL_RS02700
uniprot id: C6WU43
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

583345:MMOL RS01200
gene id: 583345:MMOL_RS01200
uniprot id: C6WSQ3
names: Similarity
messages: Belongs to the MT-A70-like family.

583345:MMOL RS11070
gene id: 583345:MMOL_RS11070
uniprot id: C6WT29
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

583345:MMOL RS08695
gene id: 583345:MMOL_RS08695
uniprot id: C6WXH1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS03780
gene id: 583345:MMOL_RS03780
uniprot id: C6WUQ4
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04225
gene id: 583345:MMOL_RS04225
uniprot id: C6WUZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

583345:MMOL RS08025
gene id: 583345:MMOL_RS08025
uniprot id: C6WX38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583345:MMOL RS03000
gene id: 583345:MMOL_RS03000
uniprot id: C6WUA3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

583345:MMOL RS02955
gene id: 583345:MMOL_RS02955
uniprot id: C6WU94
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583345:MMOL RS06275
gene id: 583345:MMOL_RS06275
uniprot id: C6WW43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

583345:MMOL RS01730
gene id: 583345:MMOL_RS01730
uniprot id: C6WTC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

583345:MMOL RS07965
gene id: 583345:MMOL_RS07965
uniprot id: C6WX27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm

583345:MMOL RS06715
gene id: 583345:MMOL_RS06715
uniprot id: C6WWC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

583345:MMOL RS05715
gene id: 583345:MMOL_RS05715
uniprot id: C6WVT5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

583345:MMOL RS04020
gene id: 583345:MMOL_RS04020
uniprot id: C6WUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

583345:MMOL RS08050
gene id: 583345:MMOL_RS08050
uniprot id: C6WX43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS01700
gene id: 583345:MMOL_RS01700
uniprot id: C6WTB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

583345:MMOL RS11270
gene id: 583345:MMOL_RS11270
uniprot id: C6WT68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

583345:MMOL RS07995
gene id: 583345:MMOL_RS07995
uniprot id: C6WX33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

583345:MMOL RS11380
gene id: 583345:MMOL_RS11380
uniprot id: C6WT90
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

583345:MMOL RS05725
gene id: 583345:MMOL_RS05725
uniprot id: C6WVT7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

583345:MMOL RS11350
gene id: 583345:MMOL_RS11350
uniprot id: C6WT84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

583345:MMOL RS09015
gene id: 583345:MMOL_RS09015
uniprot id: C6WXN4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583345:MMOL RS02550
gene id: 583345:MMOL_RS02550
uniprot id: C6WU13
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

583345:MMOL RS05530
gene id: 583345:MMOL_RS05530
uniprot id: C6WVP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

583345:MMOL RS07980
gene id: 583345:MMOL_RS07980
uniprot id: C6WX30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase heavy chain family.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm
messages: Tetramer of two light and two heavy chains.

583345:MMOL RS05855
gene id: 583345:MMOL_RS05855
uniprot id: C6WVW2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

583345:MMOL RS03295
gene id: 583345:MMOL_RS03295
uniprot id: C6WUG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

583345:MMOL RS01770
gene id: 583345:MMOL_RS01770
uniprot id: C6WTD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

583345:MMOL RS02090
gene id: 583345:MMOL_RS02090
uniprot id: C6WTJ8
names: Similarity
messages: Belongs to the LOG family.

583345:MMOL RS04135
gene id: 583345:MMOL_RS04135
uniprot id: C6WUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS10905
gene id: 583345:MMOL_RS10905
uniprot id: C6WSZ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

583345:MMOL RS10555
gene id: 583345:MMOL_RS10555
uniprot id: C6WZ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583345:MMOL RS09920
gene id: 583345:MMOL_RS09920
uniprot id: C6WYE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583345:MMOL RS09535
gene id: 583345:MMOL_RS09535
uniprot id: C6WXY6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

583345:MMOL RS00910
gene id: 583345:MMOL_RS00910
uniprot id: C6WYX0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

583345:MMOL RS05015
gene id: 583345:MMOL_RS05015
uniprot id: C6WVE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

583345:MMOL RS09645
gene id: 583345:MMOL_RS09645
uniprot id: C6WY08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

583345:MMOL RS03620
gene id: 583345:MMOL_RS03620
uniprot id: C6WUM2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

583345:MMOL RS07740
gene id: 583345:MMOL_RS07740
uniprot id: C6WWY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS04005
gene id: 583345:MMOL_RS04005
uniprot id: C6WUU6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS07595
gene id: 583345:MMOL_RS07595
uniprot id: C6WWV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

583345:MMOL RS02775
gene id: 583345:MMOL_RS02775
uniprot id: C6WU58
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04185
gene id: 583345:MMOL_RS04185
uniprot id: C6WUY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

583345:MMOL RS01345
gene id: 583345:MMOL_RS01345
uniprot id: C6WST2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

583345:MMOL RS08280
gene id: 583345:MMOL_RS08280
uniprot id: C6WX88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

583345:MMOL RS04780
gene id: 583345:MMOL_RS04780
uniprot id: C6WVA0
names: Subcellular Location Annotation
messages: Secreted

583345:MMOL RS02945
gene id: 583345:MMOL_RS02945
uniprot id: C6WU92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

583345:MMOL RS11335
gene id: 583345:MMOL_RS11335
uniprot id: C6WT81
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

583345:MMOL RS08170
gene id: 583345:MMOL_RS08170
uniprot id: C6WX65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

583345:MMOL RS10075
gene id: 583345:MMOL_RS10075
uniprot id: C6WYH0
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

583345:MMOL RS10385
gene id: 583345:MMOL_RS10385
uniprot id: C6WZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

583345:MMOL RS09570
gene id: 583345:MMOL_RS09570
uniprot id: C6WXZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

583345:MMOL RS10460
gene id: 583345:MMOL_RS10460
uniprot id: C6WZ20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

583345:MMOL RS08745
gene id: 583345:MMOL_RS08745
uniprot id: C6WXI1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

583345:MMOL RS01425
gene id: 583345:MMOL_RS01425
uniprot id: C6WSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS01500
gene id: 583345:MMOL_RS01500
uniprot id: C6WSW3
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

583345:MMOL RS09825
gene id: 583345:MMOL_RS09825
uniprot id: C6WYC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

583345:MMOL RS01075
gene id: 583345:MMOL_RS01075
uniprot id: C6WSN1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

583345:MMOL RS03800
gene id: 583345:MMOL_RS03800
uniprot id: C6WUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

583345:MMOL RS08190
gene id: 583345:MMOL_RS08190
uniprot id: C6WX69
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

583345:MMOL RS02875
gene id: 583345:MMOL_RS02875
uniprot id: C6WU78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

583345:MMOL RS09640
gene id: 583345:MMOL_RS09640
uniprot id: C6WY07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

583345:MMOL RS10350
gene id: 583345:MMOL_RS10350
uniprot id: C6WYZ6
names: Similarity
messages: Belongs to the PhoH family.

583345:MMOL RS04400
gene id: 583345:MMOL_RS04400
uniprot id: C6WV24
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

583345:MMOL RS01560
gene id: 583345:MMOL_RS01560
uniprot id: C6WSX5
names: Similarity
messages: Belongs to the BolA/IbaG family.

583345:MMOL RS04765
gene id: 583345:MMOL_RS04765
uniprot id: C6WV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

583345:MMOL RS06000
gene id: 583345:MMOL_RS06000
uniprot id: C6WVZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

583345:MMOL RS08245
gene id: 583345:MMOL_RS08245
uniprot id: C6WX80
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

583345:MMOL RS06440
gene id: 583345:MMOL_RS06440
uniprot id: C6WW76
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

583345:MMOL RS05290
gene id: 583345:MMOL_RS05290
uniprot id: C6WVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

583345:MMOL RS05465
gene id: 583345:MMOL_RS05465
uniprot id: C6WVN7
names: Similarity
messages: Belongs to the bacterial secretin family.

583345:MMOL RS10495
gene id: 583345:MMOL_RS10495
uniprot id: C6WZ27
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

583345:MMOL RS01165
gene id: 583345:MMOL_RS01165
uniprot id: C6WSP6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

583345:MMOL RS10915
gene id: 583345:MMOL_RS10915
uniprot id: C6WSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

583345:MMOL RS07350
gene id: 583345:MMOL_RS07350
uniprot id: C6WWQ5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583345:MMOL RS11240
gene id: 583345:MMOL_RS11240
uniprot id: C6WT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

583345:MMOL RS09735
gene id: 583345:MMOL_RS09735
uniprot id: C6WYA4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

583345:MMOL RS01855
gene id: 583345:MMOL_RS01855
uniprot id: C6WTE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

583345:MMOL RS08610
gene id: 583345:MMOL_RS08610
uniprot id: C6WXF4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

583345:MMOL RS10705
gene id: 583345:MMOL_RS10705
uniprot id: C6WZ70
names: Similarity
messages: Belongs to the UPF0047 family.

583345:MMOL RS02825
gene id: 583345:MMOL_RS02825
uniprot id: C6WU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

583345:MMOL RS05850
gene id: 583345:MMOL_RS05850
uniprot id: C6WVW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

583345:MMOL RS03915
gene id: 583345:MMOL_RS03915
uniprot id: C6WUT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

583345:MMOL RS01410
gene id: 583345:MMOL_RS01410
uniprot id: C6WSU5
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

583345:MMOL RS10685
gene id: 583345:MMOL_RS10685
uniprot id: C6WZ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

583345:MMOL RS10500
gene id: 583345:MMOL_RS10500
uniprot id: C6WZ28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

583345:MMOL RS04760
gene id: 583345:MMOL_RS04760
uniprot id: C6WV96
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

583345:MMOL RS09955
gene id: 583345:MMOL_RS09955
uniprot id: C6WYE7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583345:MMOL RS04690
gene id: 583345:MMOL_RS04690
uniprot id: C6WV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

583345:MMOL RS11125
gene id: 583345:MMOL_RS11125
uniprot id: C6WT39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS08135
gene id: 583345:MMOL_RS08135
uniprot id: C6WX59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583345:MMOL RS10235
gene id: 583345:MMOL_RS10235
uniprot id: C6WYK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

583345:MMOL RS11600
gene id: 583345:MMOL_RS11600
uniprot id: C6WTQ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS01750
gene id: 583345:MMOL_RS01750
uniprot id: C6WTC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

583345:MMOL RS01765
gene id: 583345:MMOL_RS01765
uniprot id: C6WTB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

583345:MMOL RS06945
gene id: 583345:MMOL_RS06945
uniprot id: C6WWH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

583345:MMOL RS04525
gene id: 583345:MMOL_RS04525
uniprot id: C6WV50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

583345:MMOL RS01415
gene id: 583345:MMOL_RS01415
uniprot id: C6WSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

583345:MMOL RS09775
gene id: 583345:MMOL_RS09775
uniprot id: C6WYB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

583345:MMOL RS03710
gene id: 583345:MMOL_RS03710
uniprot id: C6WUP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

583345:MMOL RS04520
gene id: 583345:MMOL_RS04520
uniprot id: C6WV49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583345:MMOL RS00170
gene id: 583345:MMOL_RS00170
uniprot id: C6WY49
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04255
gene id: 583345:MMOL_RS04255
uniprot id: C6WUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

583345:MMOL RS05180
gene id: 583345:MMOL_RS05180
uniprot id: C6WVI1
names: Similarity
messages: Belongs to the HSP15 family.

583345:MMOL RS01660
gene id: 583345:MMOL_RS01660
uniprot id: C6WTB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

583345:MMOL RS10285
gene id: 583345:MMOL_RS10285
uniprot id: C6WYL2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

583345:MMOL RS10800
gene id: 583345:MMOL_RS10800
uniprot id: C6WZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

583345:MMOL RS09845
gene id: 583345:MMOL_RS09845
uniprot id: C6WYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

583345:MMOL RS04440
gene id: 583345:MMOL_RS04440
uniprot id: C6WV32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

583345:MMOL RS10005
gene id: 583345:MMOL_RS10005
uniprot id: C6WYF7
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04945
gene id: 583345:MMOL_RS04945
uniprot id: C6WVD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

583345:MMOL RS08005
gene id: 583345:MMOL_RS08005
uniprot id: C6WX35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

583345:MMOL RS03140
gene id: 583345:MMOL_RS03140
uniprot id: C6WUD1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

583345:MMOL RS03760
gene id: 583345:MMOL_RS03760
uniprot id: C6WUQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

583345:MMOL RS04215
gene id: 583345:MMOL_RS04215
uniprot id: C6WUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

583345:MMOL RS08435
gene id: 583345:MMOL_RS08435
uniprot id: C6WXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

583345:MMOL RS00150
gene id: 583345:MMOL_RS00150
uniprot id: C6WY45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS05585
gene id: 583345:MMOL_RS05585
uniprot id: C6WVQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583345:MMOL RS01755
gene id: 583345:MMOL_RS01755
uniprot id: C6WTC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

583345:MMOL RS04905
gene id: 583345:MMOL_RS04905
uniprot id: C6WVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

583345:MMOL RS05435
gene id: 583345:MMOL_RS05435
uniprot id: C6WVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

583345:MMOL RS08475
gene id: 583345:MMOL_RS08475
uniprot id: C6WXC7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

583345:MMOL RS11360
gene id: 583345:MMOL_RS11360
uniprot id: C6WT86
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS11215
gene id: 583345:MMOL_RS11215
uniprot id: C6WT57
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS09650
gene id: 583345:MMOL_RS09650
uniprot id: C6WY09
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

583345:MMOL RS02235
gene id: 583345:MMOL_RS02235
uniprot id: C6WTM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

583345:MMOL RS09555
gene id: 583345:MMOL_RS09555
uniprot id: C6WXZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

583345:MMOL RS11725
gene id: 583345:MMOL_RS11725
uniprot id: C6WTS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

583345:MMOL RS07860
gene id: 583345:MMOL_RS07860
uniprot id: C6WX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

583345:MMOL RS02210
gene id: 583345:MMOL_RS02210
uniprot id: C6WTM3
names: Similarity
messages: Belongs to the peptidase S13 family.

583345:MMOL RS10490
gene id: 583345:MMOL_RS10490
uniprot id: C6WZ26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

583345:MMOL RS09740
gene id: 583345:MMOL_RS09740
uniprot id: C6WYA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

583345:MMOL RS00300
gene id: 583345:MMOL_RS00300
uniprot id: C6WY77
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

583345:MMOL RS06660
gene id: 583345:MMOL_RS06660
uniprot id: C6WWC0
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS05900
gene id: 583345:MMOL_RS05900
uniprot id: C6WVX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

583345:MMOL RS08080
gene id: 583345:MMOL_RS08080
uniprot id: C6WX48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583345:MMOL RS02935
gene id: 583345:MMOL_RS02935
uniprot id: C6WU90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

583345:MMOL RS00715
gene id: 583345:MMOL_RS00715
uniprot id: C6WYT1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

583345:MMOL RS07125
gene id: 583345:MMOL_RS07125
uniprot id: C6WWL0
names: Similarity
messages: Belongs to the peptidase A24 family.

583345:MMOL RS08955
gene id: 583345:MMOL_RS08955
uniprot id: C6WXM2
names: Subcellular Location Annotation
messages: Cytoplasm

583345:MMOL RS03245
gene id: 583345:MMOL_RS03245
uniprot id: C6WUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

583345:MMOL RS02910
gene id: 583345:MMOL_RS02910
uniprot id: C6WU85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

583345:MMOL RS02995
gene id: 583345:MMOL_RS02995
uniprot id: C6WUA2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

583345:MMOL RS11300
gene id: 583345:MMOL_RS11300
uniprot id: C6WT74
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS03675
gene id: 583345:MMOL_RS03675
uniprot id: C6WUN3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

583345:MMOL RS11745
gene id: 583345:MMOL_RS11745
uniprot id: C6WTT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583345:MMOL RS11160
gene id: 583345:MMOL_RS11160
uniprot id: C6WT46
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS05195
gene id: 583345:MMOL_RS05195
uniprot id: C6WVI4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

583345:MMOL RS00975
gene id: 583345:MMOL_RS00975
uniprot id: C6WYY3
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

583345:MMOL RS03010
gene id: 583345:MMOL_RS03010
uniprot id: C6WUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

583345:MMOL RS02920
gene id: 583345:MMOL_RS02920
uniprot id: C6WU87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01780
gene id: 583345:MMOL_RS01780
uniprot id: C6WTD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

583345:MMOL RS06430
gene id: 583345:MMOL_RS06430
uniprot id: C6WW74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

583345:MMOL RS02655
gene id: 583345:MMOL_RS02655
uniprot id: C6WU34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

583345:MMOL RS03155
gene id: 583345:MMOL_RS03155
uniprot id: C6WUD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS09935
gene id: 583345:MMOL_RS09935
uniprot id: C6WYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583345:MMOL RS04210
gene id: 583345:MMOL_RS04210
uniprot id: C6WUY7
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

583345:MMOL RS05350
gene id: 583345:MMOL_RS05350
uniprot id: C6WVL4
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

583345:MMOL RS06205
gene id: 583345:MMOL_RS06205
uniprot id: C6WW29
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

583345:MMOL RS08935
gene id: 583345:MMOL_RS08935
uniprot id: C6WXL8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS03215
gene id: 583345:MMOL_RS03215
uniprot id: C6WUE6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

583345:MMOL RS05045
gene id: 583345:MMOL_RS05045
uniprot id: C6WVF4
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

583345:MMOL RS02445
gene id: 583345:MMOL_RS02445
uniprot id: C6WTZ3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

583345:MMOL RS03490
gene id: 583345:MMOL_RS03490
uniprot id: C6WUJ5
names: Similarity
messages: Belongs to the FeoA family.

583345:MMOL RS10615
gene id: 583345:MMOL_RS10615
uniprot id: C6WZ51
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

583345:MMOL RS05835
gene id: 583345:MMOL_RS05835
uniprot id: C6WVV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

583345:MMOL RS11390
gene id: 583345:MMOL_RS11390
uniprot id: C6WT92
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

583345:MMOL RS05865
gene id: 583345:MMOL_RS05865
uniprot id: C6WVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

583345:MMOL RS06620
gene id: 583345:MMOL_RS06620
uniprot id: C6WWB2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

583345:MMOL RS03330
gene id: 583345:MMOL_RS03330
uniprot id: C6WUG3
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

583345:MMOL RS09000
gene id: 583345:MMOL_RS09000
uniprot id: C6WXN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS11785
gene id: 583345:MMOL_RS11785
uniprot id: C6WTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

583345:MMOL RS08095
gene id: 583345:MMOL_RS08095
uniprot id: C6WX51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583345:MMOL RS00240
gene id: 583345:MMOL_RS00240
uniprot id: C6WY64
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

583345:MMOL RS09445
gene id: 583345:MMOL_RS09445
uniprot id: C6WXW8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

583345:MMOL RS03165
gene id: 583345:MMOL_RS03165
uniprot id: C6WUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS04500
gene id: 583345:MMOL_RS04500
uniprot id: C6WV45
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS02540
gene id: 583345:MMOL_RS02540
uniprot id: C6WU11
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS08655
gene id: 583345:MMOL_RS08655
uniprot id: C6WXG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

583345:MMOL RS03110
gene id: 583345:MMOL_RS03110
uniprot id: C6WUC5
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

583345:MMOL RS07235
gene id: 583345:MMOL_RS07235
uniprot id: C6WWN2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

583345:MMOL RS08700
gene id: 583345:MMOL_RS08700
uniprot id: C6WXH2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

583345:MMOL RS04820
gene id: 583345:MMOL_RS04820
uniprot id: C6WVA8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

583345:MMOL RS03195
gene id: 583345:MMOL_RS03195
uniprot id: C6WUE2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

583345:MMOL RS01905
gene id: 583345:MMOL_RS01905
uniprot id: C6WTG0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

583345:MMOL RS02750
gene id: 583345:MMOL_RS02750
uniprot id: C6WU53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

583345:MMOL RS04435
gene id: 583345:MMOL_RS04435
uniprot id: C6WV31
names: Similarity
messages: Belongs to the YfgM family.

583345:MMOL RS10145
gene id: 583345:MMOL_RS10145
uniprot id: C6WYI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

583345:MMOL RS05870
gene id: 583345:MMOL_RS05870
uniprot id: C6WVW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

583345:MMOL RS07250
gene id: 583345:MMOL_RS07250
uniprot id: C6WWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

583345:MMOL RS01315
gene id: 583345:MMOL_RS01315
uniprot id: C6WSS6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

583345:MMOL RS04140
gene id: 583345:MMOL_RS04140
uniprot id: C6WUX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS07800
gene id: 583345:MMOL_RS07800
uniprot id: C6WWZ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

583345:MMOL RS03045
gene id: 583345:MMOL_RS03045
uniprot id: C6WUB2
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS10510
gene id: 583345:MMOL_RS10510
uniprot id: C6WZ30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS00755
gene id: 583345:MMOL_RS00755
uniprot id: C6WYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

583345:MMOL RS01610
gene id: 583345:MMOL_RS01610
uniprot id: C6WSY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

583345:MMOL RS10335
gene id: 583345:MMOL_RS10335
uniprot id: C6WYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

583345:MMOL RS07560
gene id: 583345:MMOL_RS07560
uniprot id: C6WWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

583345:MMOL RS08670
gene id: 583345:MMOL_RS08670
uniprot id: C6WXG6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

583345:MMOL RS05895
gene id: 583345:MMOL_RS05895
uniprot id: C6WVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

583345:MMOL RS10885
gene id: 583345:MMOL_RS10885
uniprot id: C6WZA6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

583345:MMOL RS02385
gene id: 583345:MMOL_RS02385
uniprot id: C6WTY1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

583345:MMOL RS11130
gene id: 583345:MMOL_RS11130
uniprot id: C6WT40
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

583345:MMOL RS02860
gene id: 583345:MMOL_RS02860
uniprot id: C6WU75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

583345:MMOL RS05985
gene id: 583345:MMOL_RS05985
uniprot id: C6WVY7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

583345:MMOL RS09835
gene id: 583345:MMOL_RS09835
uniprot id: C6WYC3
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS02115
gene id: 583345:MMOL_RS02115
uniprot id: C6WTK3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

583345:MMOL RS00735
gene id: 583345:MMOL_RS00735
uniprot id: C6WYT5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS00035
gene id: 583345:MMOL_RS00035
uniprot id: C6WY21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS07245
gene id: 583345:MMOL_RS07245
uniprot id: C6WWN4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

583345:MMOL RS07770
gene id: 583345:MMOL_RS07770
uniprot id: C6WWY8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

583345:MMOL RS10785
gene id: 583345:MMOL_RS10785
uniprot id: C6WZ86
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS11045
gene id: 583345:MMOL_RS11045
uniprot id: C6WT24
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

583345:MMOL RS03485
gene id: 583345:MMOL_RS03485
uniprot id: C6WUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

583345:MMOL RS09515
gene id: 583345:MMOL_RS09515
uniprot id: C6WXY2
names: Similarity
messages: Belongs to the SCO1/2 family.

583345:MMOL RS01760
gene id: 583345:MMOL_RS01760
uniprot id: C6WTD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

583345:MMOL RS10310
gene id: 583345:MMOL_RS10310
uniprot id: C6WYY8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

583345:MMOL RS10035
gene id: 583345:MMOL_RS10035
uniprot id: C6WYG3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

583345:MMOL RS05140
gene id: 583345:MMOL_RS05140
uniprot id: C6WVH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

583345:MMOL RS06915
gene id: 583345:MMOL_RS06915
uniprot id: C6WWG7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

583345:MMOL RS09755
gene id: 583345:MMOL_RS09755
uniprot id: C6WYA8
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04895
gene id: 583345:MMOL_RS04895
uniprot id: C6WVC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

583345:MMOL RS01295
gene id: 583345:MMOL_RS01295
uniprot id: C6WSS2
names: Similarity
messages: Belongs to the DNA photolyase family.

583345:MMOL RS00740
gene id: 583345:MMOL_RS00740
uniprot id: C6WYT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS01565
gene id: 583345:MMOL_RS01565
uniprot id: C6WSX6
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

583345:MMOL RS11850
gene id: 583345:MMOL_RS11850
uniprot id: C6WTV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01820
gene id: 583345:MMOL_RS01820
uniprot id: C6WTE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

583345:MMOL RS01710
gene id: 583345:MMOL_RS01710
uniprot id: C6WTC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS04085
gene id: 583345:MMOL_RS04085
uniprot id: C6WUW2
names: Similarity
messages: Belongs to the UPF0751 family.

583345:MMOL RS00235
gene id: 583345:MMOL_RS00235
uniprot id: C6WY63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

583345:MMOL RS06695
gene id: 583345:MMOL_RS06695
uniprot id: C6WWC5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

583345:MMOL RS00815
gene id: 583345:MMOL_RS00815
uniprot id: C6WYV1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

583345:MMOL RS04510
gene id: 583345:MMOL_RS04510
uniprot id: C6WV47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

583345:MMOL RS00850
gene id: 583345:MMOL_RS00850
uniprot id: C6WYV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

583345:MMOL RS04270
gene id: 583345:MMOL_RS04270
uniprot id: C6WUZ9
names: Subcellular Location Annotation
messages: Mitochondrion matrix

583345:MMOL RS11040
gene id: 583345:MMOL_RS11040
uniprot id: C6WT23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS02810
gene id: 583345:MMOL_RS02810
uniprot id: C6WU65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

583345:MMOL RS00855
gene id: 583345:MMOL_RS00855
uniprot id: C6WYV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

583345:MMOL RS05320
gene id: 583345:MMOL_RS05320
uniprot id: C6WVK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS03555
gene id: 583345:MMOL_RS03555
uniprot id: C6WUK8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

583345:MMOL RS10030
gene id: 583345:MMOL_RS10030
uniprot id: C6WYG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583345:MMOL RS04015
gene id: 583345:MMOL_RS04015
uniprot id: C6WUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

583345:MMOL RS06795
gene id: 583345:MMOL_RS06795
uniprot id: C6WWE3
names: Similarity
messages: Belongs to the HisA/HisF family.

583345:MMOL RS01880
gene id: 583345:MMOL_RS01880
uniprot id: C6WTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

583345:MMOL RS06860
gene id: 583345:MMOL_RS06860
uniprot id: C6WWF6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

583345:MMOL RS02950
gene id: 583345:MMOL_RS02950
uniprot id: C6WU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

583345:MMOL RS03510
gene id: 583345:MMOL_RS03510
uniprot id: C6WUJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

583345:MMOL RS05655
gene id: 583345:MMOL_RS05655
uniprot id: C6WVS3
names: Similarity
messages: Belongs to the pirin family.

583345:MMOL RS07710
gene id: 583345:MMOL_RS07710
uniprot id: C6WWX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

583345:MMOL RS03865
gene id: 583345:MMOL_RS03865
uniprot id: C6WUS2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

583345:MMOL RS05960
gene id: 583345:MMOL_RS05960
uniprot id: C6WVY2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

583345:MMOL RS06885
gene id: 583345:MMOL_RS06885
uniprot id: C6WWG1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

583345:MMOL RS09705
gene id: 583345:MMOL_RS09705
uniprot id: C6WY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS04295
gene id: 583345:MMOL_RS04295
uniprot id: C6WV05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583345:MMOL RS11225
gene id: 583345:MMOL_RS11225
uniprot id: C6WT59
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS06900
gene id: 583345:MMOL_RS06900
uniprot id: C6WWG4
names: Similarity
messages: Belongs to the histone deacetylase family.

583345:MMOL RS01615
gene id: 583345:MMOL_RS01615
uniprot id: C6WSY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS04750
gene id: 583345:MMOL_RS04750
uniprot id: C6WV94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

583345:MMOL RS11520
gene id: 583345:MMOL_RS11520
uniprot id: C6WTP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

583345:MMOL RS11155
gene id: 583345:MMOL_RS11155
uniprot id: C6WT45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

583345:MMOL RS11310
gene id: 583345:MMOL_RS11310
uniprot id: C6WT76
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS07865
gene id: 583345:MMOL_RS07865
uniprot id: C6WX07
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS08785
gene id: 583345:MMOL_RS08785
uniprot id: C6WXI9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

583345:MMOL RS09585
gene id: 583345:MMOL_RS09585
uniprot id: C6WXZ6
names: Similarity
messages: Belongs to the DNA photolyase family.

583345:MMOL RS08420
gene id: 583345:MMOL_RS08420
uniprot id: C6WXB6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS08330
gene id: 583345:MMOL_RS08330
uniprot id: C6WX98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

583345:MMOL RS08885
gene id: 583345:MMOL_RS08885
uniprot id: C6WXK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

583345:MMOL RS00040
gene id: 583345:MMOL_RS00040
uniprot id: C6WY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

583345:MMOL RS06925
gene id: 583345:MMOL_RS06925
uniprot id: C6WWG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

583345:MMOL RS07970
gene id: 583345:MMOL_RS07970
uniprot id: C6WX28
names: Function
names: Subcellular Location Annotation
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

583345:MMOL RS08175
gene id: 583345:MMOL_RS08175
uniprot id: C6WX66
names: Similarity
messages: Belongs to the RecJ family.

583345:MMOL RS06450
gene id: 583345:MMOL_RS06450
uniprot id: C6WW78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

583345:MMOL RS02130
gene id: 583345:MMOL_RS02130
uniprot id: C6WTK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS01060
gene id: 583345:MMOL_RS01060
uniprot id: C6WSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

583345:MMOL RS01860
gene id: 583345:MMOL_RS01860
uniprot id: C6WTF0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

583345:MMOL RS06370
gene id: 583345:MMOL_RS06370
uniprot id: C6WW61
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583345:MMOL RS04395
gene id: 583345:MMOL_RS04395
uniprot id: C6WV23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

583345:MMOL RS09500
gene id: 583345:MMOL_RS09500
uniprot id: C6WXX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

583345:MMOL RS08500
gene id: 583345:MMOL_RS08500
uniprot id: C6WXD2
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

583345:MMOL RS05930
gene id: 583345:MMOL_RS05930
uniprot id: C6WVX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

583345:MMOL RS08490
gene id: 583345:MMOL_RS08490
uniprot id: C6WXD0
names: Similarity
messages: Belongs to the HesB/IscA family.

583345:MMOL RS11135
gene id: 583345:MMOL_RS11135
uniprot id: C6WT41
names: Similarity
messages: Belongs to the peptidase S11 family.

583345:MMOL RS06145
gene id: 583345:MMOL_RS06145
uniprot id: C6WW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

583345:MMOL RS08405
gene id: 583345:MMOL_RS08405
uniprot id: C6WXB3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

583345:MMOL RS09680
gene id: 583345:MMOL_RS09680
uniprot id: C6WY13
names: Similarity
messages: Belongs to the FrmR/RcnR family.

583345:MMOL RS07255
gene id: 583345:MMOL_RS07255
uniprot id: C6WWN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

583345:MMOL RS05540
gene id: 583345:MMOL_RS05540
uniprot id: C6WVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

583345:MMOL RS11930
gene id: 583345:MMOL_RS11930
uniprot id: C6WX34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

583345:MMOL RS04825
gene id: 583345:MMOL_RS04825
uniprot id: C6WVA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

583345:MMOL RS08210
gene id: 583345:MMOL_RS08210
uniprot id: C6WX73
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

583345:MMOL RS00180
gene id: 583345:MMOL_RS00180
uniprot id: C6WY52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583345:MMOL RS04330
gene id: 583345:MMOL_RS04330
uniprot id: C6WV12
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS09560
gene id: 583345:MMOL_RS09560
uniprot id: C6WXZ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

583345:MMOL RS11510
gene id: 583345:MMOL_RS11510
uniprot id: C6WTN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

583345:MMOL RS07070
gene id: 583345:MMOL_RS07070
uniprot id: C6WWJ9
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS01485
gene id: 583345:MMOL_RS01485
uniprot id: C6WSW0
names: Subcellular Location Annotation
messages: Mitochondrion

583345:MMOL RS10830
gene id: 583345:MMOL_RS10830
uniprot id: C6WZ95
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

583345:MMOL RS10125
gene id: 583345:MMOL_RS10125
uniprot id: C6WYI0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

583345:MMOL RS10780
gene id: 583345:MMOL_RS10780
uniprot id: C6WZ85
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

583345:MMOL RS01920
gene id: 583345:MMOL_RS01920
uniprot id: C6WTG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

583345:MMOL RS11780
gene id: 583345:MMOL_RS11780
uniprot id: C6WTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

583345:MMOL RS01805
gene id: 583345:MMOL_RS01805
uniprot id: C6WTD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

583345:MMOL RS09405
gene id: 583345:MMOL_RS09405
uniprot id: C6WXW0
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

583345:MMOL RS10975
gene id: 583345:MMOL_RS10975
uniprot id: C6WT10
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

583345:MMOL RS05500
gene id: 583345:MMOL_RS05500
uniprot id: C6WVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

583345:MMOL RS05025
gene id: 583345:MMOL_RS05025
uniprot id: C6WVE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

583345:MMOL RS06540
gene id: 583345:MMOL_RS06540
uniprot id: C6WW96
names: Subcellular Location Annotation
messages: Cytoplasm

583345:MMOL RS04715
gene id: 583345:MMOL_RS04715
uniprot id: C6WV87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

583345:MMOL RS08160
gene id: 583345:MMOL_RS08160
uniprot id: C6WX63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS11795
gene id: 583345:MMOL_RS11795
uniprot id: C6WTU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

583345:MMOL RS07495
gene id: 583345:MMOL_RS07495
uniprot id: C6WWT3
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS06645
gene id: 583345:MMOL_RS06645
uniprot id: C6WWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS10550
gene id: 583345:MMOL_RS10550
uniprot id: C6WZ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

583345:MMOL RS03790
gene id: 583345:MMOL_RS03790
uniprot id: C6WUQ6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

583345:MMOL RS10190
gene id: 583345:MMOL_RS10190
uniprot id: C6WYJ3
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

583345:MMOL RS05770
gene id: 583345:MMOL_RS05770
uniprot id: C6WVU5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

583345:MMOL RS07855
gene id: 583345:MMOL_RS07855
uniprot id: C6WX05
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

583345:MMOL RS11450
gene id: 583345:MMOL_RS11450
uniprot id: C6WTA4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

583345:MMOL RS01090
gene id: 583345:MMOL_RS01090
uniprot id: C6WSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

583345:MMOL RS10720
gene id: 583345:MMOL_RS10720
uniprot id: C6WZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS08855
gene id: 583345:MMOL_RS08855
uniprot id: C6WXK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

583345:MMOL RS09290
gene id: 583345:MMOL_RS09290
uniprot id: C6WXT8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

583345:MMOL RS04790
gene id: 583345:MMOL_RS04790
uniprot id: C6WVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

583345:MMOL RS03135
gene id: 583345:MMOL_RS03135
uniprot id: C6WUD0
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS08615
gene id: 583345:MMOL_RS08615
uniprot id: C6WXF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

583345:MMOL RS05800
gene id: 583345:MMOL_RS05800
uniprot id: C6WVV1
names: Similarity
messages: Belongs to the fabD family.

583345:MMOL RS11230
gene id: 583345:MMOL_RS11230
uniprot id: C6WT60
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS02370
gene id: 583345:MMOL_RS02370
uniprot id: C6WTX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS07335
gene id: 583345:MMOL_RS07335
uniprot id: C6WWQ2
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS04910
gene id: 583345:MMOL_RS04910
uniprot id: C6WVC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

583345:MMOL RS05515
gene id: 583345:MMOL_RS05515
uniprot id: C6WVP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS09085
gene id: 583345:MMOL_RS09085
uniprot id: C6WXP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583345:MMOL RS09605
gene id: 583345:MMOL_RS09605
uniprot id: C6WY00
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

583345:MMOL RS11415
gene id: 583345:MMOL_RS11415
uniprot id: C6WT97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

583345:MMOL RS11365
gene id: 583345:MMOL_RS11365
uniprot id: C6WT87
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

583345:MMOL RS10205
gene id: 583345:MMOL_RS10205
uniprot id: C6WYJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

583345:MMOL RS11165
gene id: 583345:MMOL_RS11165
uniprot id: C6WT47
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS02025
gene id: 583345:MMOL_RS02025
uniprot id: C6WTI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS05640
gene id: 583345:MMOL_RS05640
uniprot id: C6WVR9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

583345:MMOL RS11770
gene id: 583345:MMOL_RS11770
uniprot id: C6WTT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS08880
gene id: 583345:MMOL_RS08880
uniprot id: C6WXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

583345:MMOL RS01935
gene id: 583345:MMOL_RS01935
uniprot id: C6WTG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

583345:MMOL RS03965
gene id: 583345:MMOL_RS03965
uniprot id: C6WUT9
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS02890
gene id: 583345:MMOL_RS02890
uniprot id: C6WU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

583345:MMOL RS11595
gene id: 583345:MMOL_RS11595
uniprot id: C6WTQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS10845
gene id: 583345:MMOL_RS10845
uniprot id: C6WZ98
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

583345:MMOL RS07110
gene id: 583345:MMOL_RS07110
uniprot id: C6WWK7
names: Similarity
messages: Belongs to the bacterial secretin family.

583345:MMOL RS08155
gene id: 583345:MMOL_RS08155
uniprot id: C6WX62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

583345:MMOL RS01840
gene id: 583345:MMOL_RS01840
uniprot id: C6WTE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

583345:MMOL RS09365
gene id: 583345:MMOL_RS09365
uniprot id: C6WXV2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

583345:MMOL RS11065
gene id: 583345:MMOL_RS11065
uniprot id: C6WT28
names: Similarity
messages: Belongs to the Smg family.

583345:MMOL RS10465
gene id: 583345:MMOL_RS10465
uniprot id: C6WZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

583345:MMOL RS01815
gene id: 583345:MMOL_RS01815
uniprot id: C6WTE1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

583345:MMOL RS00965
gene id: 583345:MMOL_RS00965
uniprot id: C6WYY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

583345:MMOL RS01465
gene id: 583345:MMOL_RS01465
uniprot id: C6WSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

583345:MMOL RS01310
gene id: 583345:MMOL_RS01310
uniprot id: C6WSS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

583345:MMOL RS11370
gene id: 583345:MMOL_RS11370
uniprot id: C6WT88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

583345:MMOL RS11080
gene id: 583345:MMOL_RS11080
uniprot id: C6WT31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

583345:MMOL RS04605
gene id: 583345:MMOL_RS04605
uniprot id: C6WV65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

583345:MMOL RS05205
gene id: 583345:MMOL_RS05205
uniprot id: C6WVI6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01900
gene id: 583345:MMOL_RS01900
uniprot id: C6WTF9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

583345:MMOL RS10060
gene id: 583345:MMOL_RS10060
uniprot id: C6WYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

583345:MMOL RS02475
gene id: 583345:MMOL_RS02475
uniprot id: C6WTZ8
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

583345:MMOL RS08265
gene id: 583345:MMOL_RS08265
uniprot id: C6WX85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

583345:MMOL RS10900
gene id: 583345:MMOL_RS10900
uniprot id: C6WSZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

583345:MMOL RS07005
gene id: 583345:MMOL_RS07005
uniprot id: C6WWI5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

583345:MMOL RS11580
gene id: 583345:MMOL_RS11580
uniprot id: C6WTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS08035
gene id: 583345:MMOL_RS08035
uniprot id: C6WX40
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

583345:MMOL RS07215
gene id: 583345:MMOL_RS07215
uniprot id: C6WWM8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

583345:MMOL RS11565
gene id: 583345:MMOL_RS11565
uniprot id: C6WTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

583345:MMOL RS06490
gene id: 583345:MMOL_RS06490
uniprot id: C6WW86
names: Similarity
messages: Belongs to the DEAD box helicase family.

583345:MMOL RS05825
gene id: 583345:MMOL_RS05825
uniprot id: C6WVV6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

583345:MMOL RS10160
gene id: 583345:MMOL_RS10160
uniprot id: C6WYI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

583345:MMOL RS10645
gene id: 583345:MMOL_RS10645
uniprot id: C6WZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

583345:MMOL RS10000
gene id: 583345:MMOL_RS10000
uniprot id: C6WYF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

583345:MMOL RS02175
gene id: 583345:MMOL_RS02175
uniprot id: C6WTL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

583345:MMOL RS03375
gene id: 583345:MMOL_RS03375
uniprot id: C6WUH2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

583345:MMOL RS02315
gene id: 583345:MMOL_RS02315
uniprot id: C6WTW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS11060
gene id: 583345:MMOL_RS11060
uniprot id: C6WT27
names: Similarity
messages: Belongs to the DprA/Smf family.

583345:MMOL RS05415
gene id: 583345:MMOL_RS05415
uniprot id: C6WVM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

583345:MMOL RS00415
gene id: 583345:MMOL_RS00415
uniprot id: C6WYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

583345:MMOL RS03470
gene id: 583345:MMOL_RS03470
uniprot id: C6WUJ1
names: Similarity
messages: Belongs to the P(II) protein family.

583345:MMOL RS01870
gene id: 583345:MMOL_RS01870
uniprot id: C6WTF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

583345:MMOL RS04420
gene id: 583345:MMOL_RS04420
uniprot id: C6WV28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS02695
gene id: 583345:MMOL_RS02695
uniprot id: C6WU42
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

583345:MMOL RS03890
gene id: 583345:MMOL_RS03890
uniprot id: C6WUS7
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

583345:MMOL RS04935
gene id: 583345:MMOL_RS04935
uniprot id: C6WVD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

583345:MMOL RS01790
gene id: 583345:MMOL_RS01790
uniprot id: C6WTD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

583345:MMOL RS03970
gene id: 583345:MMOL_RS03970
uniprot id: C6WUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

583345:MMOL RS00220
gene id: 583345:MMOL_RS00220
uniprot id: C6WY60
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

583345:MMOL RS07510
gene id: 583345:MMOL_RS07510
uniprot id: C6WWT6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583345:MMOL RS10105
gene id: 583345:MMOL_RS10105
uniprot id: C6WYH6
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

583345:MMOL RS09765
gene id: 583345:MMOL_RS09765
uniprot id: C6WYB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

583345:MMOL RS09165
gene id: 583345:MMOL_RS09165
uniprot id: C6WXR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

583345:MMOL RS03645
gene id: 583345:MMOL_RS03645
uniprot id: C6WUM7
names: Similarity
messages: Belongs to the universal stress protein A family.

583345:MMOL RS00770
gene id: 583345:MMOL_RS00770
uniprot id: C6WYU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

583345:MMOL RS09010
gene id: 583345:MMOL_RS09010
uniprot id: C6WXN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS01135
gene id: 583345:MMOL_RS01135
uniprot id: C6WSP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

583345:MMOL RS04730
gene id: 583345:MMOL_RS04730
uniprot id: C6WV90
names: Subcellular Location Annotation
messages: Cytoplasm

583345:MMOL RS06455
gene id: 583345:MMOL_RS06455
uniprot id: C6WW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583345:MMOL RS01745
gene id: 583345:MMOL_RS01745
uniprot id: C6WTC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583345:MMOL RS10770
gene id: 583345:MMOL_RS10770
uniprot id: C6WZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

583345:MMOL RS00175
gene id: 583345:MMOL_RS00175
uniprot id: C6WY50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

583345:MMOL RS07210
gene id: 583345:MMOL_RS07210
uniprot id: C6WWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

583345:MMOL RS01025
gene id: 583345:MMOL_RS01025
uniprot id: C6WSM1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

583345:MMOL RS02545
gene id: 583345:MMOL_RS02545
uniprot id: C6WU12
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

583345:MMOL RS02060
gene id: 583345:MMOL_RS02060
uniprot id: C6WTJ1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

583345:MMOL RS03160
gene id: 583345:MMOL_RS03160
uniprot id: C6WUD5
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

583345:MMOL RS11805
gene id: 583345:MMOL_RS11805
uniprot id: C6WTU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

583345:MMOL RS08480
gene id: 583345:MMOL_RS08480
uniprot id: C6WXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

583345:MMOL RS05535
gene id: 583345:MMOL_RS05535
uniprot id: C6WVP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

583345:MMOL RS09185
gene id: 583345:MMOL_RS09185
uniprot id: C6WXR8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

583345:MMOL RS08800
gene id: 583345:MMOL_RS08800
uniprot id: C6WXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

583345:MMOL RS07505
gene id: 583345:MMOL_RS07505
uniprot id: C6WWT5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS04950
gene id: 583345:MMOL_RS04950
uniprot id: C6WVD4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS09715
gene id: 583345:MMOL_RS09715
uniprot id: C6WYA0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS00710
gene id: 583345:MMOL_RS00710
uniprot id: C6WYT0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

583345:MMOL RS08620
gene id: 583345:MMOL_RS08620
uniprot id: C6WXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

583345:MMOL RS11790
gene id: 583345:MMOL_RS11790
uniprot id: C6WTU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

583345:MMOL RS08705
gene id: 583345:MMOL_RS08705
uniprot id: C6WXH3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

583345:MMOL RS05995
gene id: 583345:MMOL_RS05995
uniprot id: C6WVY9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

583345:MMOL RS09860
gene id: 583345:MMOL_RS09860
uniprot id: C6WYC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

583345:MMOL RS07275
gene id: 583345:MMOL_RS07275
uniprot id: C6WWP0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

583345:MMOL RS05520
gene id: 583345:MMOL_RS05520
uniprot id: C6WVP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

583345:MMOL RS10165
gene id: 583345:MMOL_RS10165
uniprot id: C6WYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

583345:MMOL RS04485
gene id: 583345:MMOL_RS04485
uniprot id: C6WV42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

583345:MMOL RS02055
gene id: 583345:MMOL_RS02055
uniprot id: C6WTJ0
names: Similarity
messages: Belongs to the GARS family.

583345:MMOL RS01975
gene id: 583345:MMOL_RS01975
uniprot id: C6WTH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

583345:MMOL RS00785
gene id: 583345:MMOL_RS00785
uniprot id: C6WYU5
names: Similarity
messages: Belongs to the CutA family.

583345:MMOL RS00585
gene id: 583345:MMOL_RS00585
uniprot id: C6WYQ5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

583345:MMOL RS09575
gene id: 583345:MMOL_RS09575
uniprot id: C6WXZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

583345:MMOL RS05990
gene id: 583345:MMOL_RS05990
uniprot id: C6WVY8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

583345:MMOL RS01080
gene id: 583345:MMOL_RS01080
uniprot id: C6WSN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

583345:MMOL RS10890
gene id: 583345:MMOL_RS10890
uniprot id: C6WZA7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

583345:MMOL RS08090
gene id: 583345:MMOL_RS08090
uniprot id: C6WX50
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS05885
gene id: 583345:MMOL_RS05885
uniprot id: C6WVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

583345:MMOL RS09485
gene id: 583345:MMOL_RS09485
uniprot id: C6WXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

583345:MMOL RS04785
gene id: 583345:MMOL_RS04785
uniprot id: C6WVA1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

583345:MMOL RS01810
gene id: 583345:MMOL_RS01810
uniprot id: C6WTE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

583345:MMOL RS11110
gene id: 583345:MMOL_RS11110
uniprot id: C6WT37
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

583345:MMOL RS03030
gene id: 583345:MMOL_RS03030
uniprot id: C6WUA9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

583345:MMOL RS02125
gene id: 583345:MMOL_RS02125
uniprot id: C6WTK6
names: Similarity
messages: Belongs to the pirin family.

583345:MMOL RS07725
gene id: 583345:MMOL_RS07725
uniprot id: C6WWX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

583345:MMOL RS05010
gene id: 583345:MMOL_RS05010
uniprot id: C6WVE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01890
gene id: 583345:MMOL_RS01890
uniprot id: C6WTF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

583345:MMOL RS00700
gene id: 583345:MMOL_RS00700
uniprot id: C6WYS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

583345:MMOL RS03040
gene id: 583345:MMOL_RS03040
uniprot id: C6WUB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

583345:MMOL RS01595
gene id: 583345:MMOL_RS01595
uniprot id: C6WSY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

583345:MMOL RS02535
gene id: 583345:MMOL_RS02535
uniprot id: C6WU10
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

583345:MMOL RS11695
gene id: 583345:MMOL_RS11695
uniprot id: C6WTS4
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS06375
gene id: 583345:MMOL_RS06375
uniprot id: C6WW62
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583345:MMOL RS11330
gene id: 583345:MMOL_RS11330
uniprot id: C6WT80
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

583345:MMOL RS11290
gene id: 583345:MMOL_RS11290
uniprot id: C6WT72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

583345:MMOL RS01775
gene id: 583345:MMOL_RS01775
uniprot id: C6WTD3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

583345:MMOL RS02975
gene id: 583345:MMOL_RS02975
uniprot id: C6WU98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

583345:MMOL RS02645
gene id: 583345:MMOL_RS02645
uniprot id: C6WU32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

583345:MMOL RS01570
gene id: 583345:MMOL_RS01570
uniprot id: C6WSX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01845
gene id: 583345:MMOL_RS01845
uniprot id: C6WTE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

583345:MMOL RS04465
gene id: 583345:MMOL_RS04465
uniprot id: C6WV37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

583345:MMOL RS10475
gene id: 583345:MMOL_RS10475
uniprot id: C6WZ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

583345:MMOL RS04810
gene id: 583345:MMOL_RS04810
uniprot id: C6WVA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

583345:MMOL RS04990
gene id: 583345:MMOL_RS04990
uniprot id: C6WVE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

583345:MMOL RS01735
gene id: 583345:MMOL_RS01735
uniprot id: C6WTC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

583345:MMOL RS03250
gene id: 583345:MMOL_RS03250
uniprot id: C6WUF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

583345:MMOL RS11095
gene id: 583345:MMOL_RS11095
uniprot id: C6WT34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS01875
gene id: 583345:MMOL_RS01875
uniprot id: C6WTF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

583345:MMOL RS10655
gene id: 583345:MMOL_RS10655
uniprot id: C6WZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

583345:MMOL RS09230
gene id: 583345:MMOL_RS09230
uniprot id: C6WXS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

583345:MMOL RS09245
gene id: 583345:MMOL_RS09245
uniprot id: C6WXT0
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS11205
gene id: 583345:MMOL_RS11205
uniprot id: C6WT55
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS00985
gene id: 583345:MMOL_RS00985
uniprot id: C6WYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS09820
gene id: 583345:MMOL_RS09820
uniprot id: C6WYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

583345:MMOL RS11245
gene id: 583345:MMOL_RS11245
uniprot id: C6WT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583345:MMOL RS08115
gene id: 583345:MMOL_RS08115
uniprot id: C6WX55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

583345:MMOL RS09210
gene id: 583345:MMOL_RS09210
uniprot id: C6WXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

583345:MMOL RS02375
gene id: 583345:MMOL_RS02375
uniprot id: C6WTX9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583345:MMOL RS00085
gene id: 583345:MMOL_RS00085
uniprot id: C6WY31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

583345:MMOL RS10545
gene id: 583345:MMOL_RS10545
uniprot id: C6WZ37
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

583345:MMOL RS08660
gene id: 583345:MMOL_RS08660
uniprot id: C6WXG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

583345:MMOL RS08635
gene id: 583345:MMOL_RS08635
uniprot id: C6WXF9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

583345:MMOL RS02885
gene id: 583345:MMOL_RS02885
uniprot id: C6WU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

583345:MMOL RS05090
gene id: 583345:MMOL_RS05090
uniprot id: C6WVG3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

583345:MMOL RS03530
gene id: 583345:MMOL_RS03530
uniprot id: C6WUK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS01885
gene id: 583345:MMOL_RS01885
uniprot id: C6WTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

583345:MMOL RS02630
gene id: 583345:MMOL_RS02630
uniprot id: C6WU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

583345:MMOL RS11090
gene id: 583345:MMOL_RS11090
uniprot id: C6WT33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

583345:MMOL RS05115
gene id: 583345:MMOL_RS05115
uniprot id: C6WVG8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583345:MMOL RS09455
gene id: 583345:MMOL_RS09455
uniprot id: C6WXX0
names: Similarity
messages: Belongs to the PhoH family.

583345:MMOL RS09905
gene id: 583345:MMOL_RS09905
uniprot id: C6WYD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

583345:MMOL RS10170
gene id: 583345:MMOL_RS10170
uniprot id: C6WYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

583345:MMOL RS03920
gene id: 583345:MMOL_RS03920
uniprot id: C6WUT3
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS07075
gene id: 583345:MMOL_RS07075
uniprot id: C6WWK0
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS03505
gene id: 583345:MMOL_RS03505
uniprot id: C6WUJ8
names: Similarity
messages: Belongs to the YciI family.

583345:MMOL RS04235
gene id: 583345:MMOL_RS04235
uniprot id: C6WUZ2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

583345:MMOL RS10320
gene id: 583345:MMOL_RS10320
uniprot id: C6WYZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

583345:MMOL RS11675
gene id: 583345:MMOL_RS11675
uniprot id: C6WTS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS10540
gene id: 583345:MMOL_RS10540
uniprot id: C6WZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

583345:MMOL RS02685
gene id: 583345:MMOL_RS02685
uniprot id: C6WU40
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

583345:MMOL RS11325
gene id: 583345:MMOL_RS11325
uniprot id: C6WT79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

583345:MMOL RS04955
gene id: 583345:MMOL_RS04955
uniprot id: C6WVD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583345:MMOL RS03850
gene id: 583345:MMOL_RS03850
uniprot id: C6WUR9
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

583345:MMOL RS04840
gene id: 583345:MMOL_RS04840
uniprot id: C6WVB2
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

583345:MMOL RS05690
gene id: 583345:MMOL_RS05690
uniprot id: C6WVT0
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS03455
gene id: 583345:MMOL_RS03455
uniprot id: C6WUI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

583345:MMOL RS04735
gene id: 583345:MMOL_RS04735
uniprot id: C6WV91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

583345:MMOL RS04685
gene id: 583345:MMOL_RS04685
uniprot id: C6WV81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

583345:MMOL RS01290
gene id: 583345:MMOL_RS01290
uniprot id: C6WSS1
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS06485
gene id: 583345:MMOL_RS06485
uniprot id: C6WW85
names: Similarity
messages: Belongs to the DEAD box helicase family.

583345:MMOL RS11405
gene id: 583345:MMOL_RS11405
uniprot id: C6WT95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

583345:MMOL RS02660
gene id: 583345:MMOL_RS02660
uniprot id: C6WU35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

583345:MMOL RS01645
gene id: 583345:MMOL_RS01645
uniprot id: C6WSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

583345:MMOL RS09045
gene id: 583345:MMOL_RS09045
uniprot id: C6WXP0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

583345:MMOL RS00425
gene id: 583345:MMOL_RS00425
uniprot id: C6WYM3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583345:MMOL RS07375
gene id: 583345:MMOL_RS07375
uniprot id: C6WWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

583345:MMOL RS09940
gene id: 583345:MMOL_RS09940
uniprot id: C6WYE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

583345:MMOL RS02100
gene id: 583345:MMOL_RS02100
uniprot id: C6WTK0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

583345:MMOL RS03255
gene id: 583345:MMOL_RS03255
uniprot id: C6WUF4
names: Subcellular Location Annotation
messages: Membrane

583345:MMOL RS11455
gene id: 583345:MMOL_RS11455
uniprot id: C6WTA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

583345:MMOL RS00780
gene id: 583345:MMOL_RS00780
uniprot id: C6WYU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

583345:MMOL RS11765
gene id: 583345:MMOL_RS11765
uniprot id: C6WTT7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

583345:MMOL RS04580
gene id: 583345:MMOL_RS04580
uniprot id: C6WV60
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

583345:MMOL RS11440
gene id: 583345:MMOL_RS11440
uniprot id: C6WTA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

583345:MMOL RS03205
gene id: 583345:MMOL_RS03205
uniprot id: C6WUE4
names: Similarity
messages: Belongs to the GSP E family.

583345:MMOL RS03280
gene id: 583345:MMOL_RS03280
uniprot id: C6WUF9
names: Subcellular Location Annotation
messages: Membrane