582419:TES1 RS01005
gene id: 582419:TES1_RS01005
uniprot id: W0I0R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS04015
gene id: 582419:TES1_RS04015
uniprot id: W0I2B5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

582419:TES1 RS06345
gene id: 582419:TES1_RS06345
uniprot id: W0I3I0
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04705
gene id: 582419:TES1_RS04705
uniprot id: W0I781
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04640
gene id: 582419:TES1_RS04640
uniprot id: W0I774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

582419:TES1 RS06075
gene id: 582419:TES1_RS06075
uniprot id: W0I3D1
names: Similarity
messages: Belongs to the PDCD5 family.

582419:TES1 RS07770
gene id: 582419:TES1_RS07770
uniprot id: W0I8V2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS06140
gene id: 582419:TES1_RS06140
uniprot id: W0I3B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

582419:TES1 RS04295
gene id: 582419:TES1_RS04295
uniprot id: W0I634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS01580
gene id: 582419:TES1_RS01580
uniprot id: W0I4N1
names: Similarity
messages: Belongs to the UPF0175 family.

582419:TES1 RS07160
gene id: 582419:TES1_RS07160
uniprot id: W0I3X2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

582419:TES1 RS10325
gene id: 582419:TES1_RS10325
uniprot id: W0I5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

582419:TES1 RS03550
gene id: 582419:TES1_RS03550
uniprot id: W0I5R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

582419:TES1 RS07910
gene id: 582419:TES1_RS07910
uniprot id: W0I4A8
names: Similarity
messages: Belongs to the UPF0201 family.

582419:TES1 RS04305
gene id: 582419:TES1_RS04305
uniprot id: W0I2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS00800
gene id: 582419:TES1_RS00800
uniprot id: W0I595
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

582419:TES1 RS00350
gene id: 582419:TES1_RS00350
uniprot id: W0I520
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS09880
gene id: 582419:TES1_RS09880
uniprot id: W0I9W2
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01055
gene id: 582419:TES1_RS01055
uniprot id: W0I0S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS07225
gene id: 582419:TES1_RS07225
uniprot id: W0I7M2
names: Similarity
messages: Belongs to the HypE family.

582419:TES1 RS10460
gene id: 582419:TES1_RS10460
uniprot id: W0IA63
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

582419:TES1 RS08970
gene id: 582419:TES1_RS08970
uniprot id: W0I4V2
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

582419:TES1 RS04040
gene id: 582419:TES1_RS04040
uniprot id: W0I2C0
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS06095
gene id: 582419:TES1_RS06095
uniprot id: W0I805
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04710
gene id: 582419:TES1_RS04710
uniprot id: W0I2N3
names: Similarity
messages: Belongs to the UPF0107 family.

582419:TES1 RS00680
gene id: 582419:TES1_RS00680
uniprot id: W0I489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS02135
gene id: 582419:TES1_RS02135
uniprot id: W0I4X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS08555
gene id: 582419:TES1_RS08555
uniprot id: W0I4N6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

582419:TES1 RS09370
gene id: 582419:TES1_RS09370
uniprot id: W0I4X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

582419:TES1 RS01315
gene id: 582419:TES1_RS01315
uniprot id: W0I0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

582419:TES1 RS05480
gene id: 582419:TES1_RS05480
uniprot id: W0I6U5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

582419:TES1 RS03860
gene id: 582419:TES1_RS03860
uniprot id: W0I6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS08115
gene id: 582419:TES1_RS08115
uniprot id: W0I4G6
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

582419:TES1 RS03990
gene id: 582419:TES1_RS03990
uniprot id: W0I2B1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS05485
gene id: 582419:TES1_RS05485
uniprot id: W0I7P4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS01130
gene id: 582419:TES1_RS01130
uniprot id: W0I0T9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

582419:TES1 RS01695
gene id: 582419:TES1_RS01695
uniprot id: W0I5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

582419:TES1 RS04335
gene id: 582419:TES1_RS04335
uniprot id: W0I6Y1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

582419:TES1 RS04115
gene id: 582419:TES1_RS04115
uniprot id: W0I6Z1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS00755
gene id: 582419:TES1_RS00755
uniprot id: W0I4A2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS07090
gene id: 582419:TES1_RS07090
uniprot id: W0I8D8
names: Similarity
messages: Belongs to the UPF0282 family.

582419:TES1 RS03955
gene id: 582419:TES1_RS03955
uniprot id: W0I2A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS04035
gene id: 582419:TES1_RS04035
uniprot id: W0I6X7
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

582419:TES1 RS00780
gene id: 582419:TES1_RS00780
uniprot id: W0I0M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

582419:TES1 RS10450
gene id: 582419:TES1_RS10450
uniprot id: W0IAA6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

582419:TES1 RS00640
gene id: 582419:TES1_RS00640
uniprot id: W0I0F2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal-type GPI family.
messages: Cytoplasm
messages: Homodimer.

582419:TES1 RS08185
gene id: 582419:TES1_RS08185
uniprot id: W0I893
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

582419:TES1 RS03070
gene id: 582419:TES1_RS03070
uniprot id: W0I1S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

582419:TES1 RS08725
gene id: 582419:TES1_RS08725
uniprot id: W0I4M2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

582419:TES1 RS03030
gene id: 582419:TES1_RS03030
uniprot id: W0I6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

582419:TES1 RS07675
gene id: 582419:TES1_RS07675
uniprot id: W0I466
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS06305
gene id: 582419:TES1_RS06305
uniprot id: W0I3D3
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01125
gene id: 582419:TES1_RS01125
uniprot id: W0I5E8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

582419:TES1 RS02605
gene id: 582419:TES1_RS02605
uniprot id: W0I667
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

582419:TES1 RS02620
gene id: 582419:TES1_RS02620
uniprot id: W0I1I5
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

582419:TES1 RS01060
gene id: 582419:TES1_RS01060
uniprot id: W0I592
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

582419:TES1 RS08275
gene id: 582419:TES1_RS08275
uniprot id: W0I8A6
names: Similarity
messages: Belongs to the UPF0310 family.

582419:TES1 RS02000
gene id: 582419:TES1_RS02000
uniprot id: W0I5Q2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

582419:TES1 RS09130
gene id: 582419:TES1_RS09130
uniprot id: W0I9L7
names: Similarity
messages: Belongs to the peptidase S9C family.

582419:TES1 RS10315
gene id: 582419:TES1_RS10315
uniprot id: W0I5J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

582419:TES1 RS05575
gene id: 582419:TES1_RS05575
uniprot id: W0I7M6
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS05090
gene id: 582419:TES1_RS05090
uniprot id: W0I2V8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

582419:TES1 RS08485
gene id: 582419:TES1_RS08485
uniprot id: W0I962
names: Similarity
messages: Belongs to the DtxR/MntR family.

582419:TES1 RS05620
gene id: 582419:TES1_RS05620
uniprot id: W0I366
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

582419:TES1 RS08150
gene id: 582419:TES1_RS08150
uniprot id: W0I911
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

582419:TES1 RS01960
gene id: 582419:TES1_RS01960
uniprot id: W0I4T8
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

582419:TES1 RS02220
gene id: 582419:TES1_RS02220
uniprot id: W0I199
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

582419:TES1 RS09975
gene id: 582419:TES1_RS09975
uniprot id: W0IA23
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

582419:TES1 RS08260
gene id: 582419:TES1_RS08260
uniprot id: W0I4F1
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

582419:TES1 RS08085
gene id: 582419:TES1_RS08085
uniprot id: W0I934
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

582419:TES1 RS00570
gene id: 582419:TES1_RS00570
uniprot id: W0I0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

582419:TES1 RS03480
gene id: 582419:TES1_RS03480
uniprot id: W0I6N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

582419:TES1 RS04565
gene id: 582419:TES1_RS04565
uniprot id: W0I2K6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS04580
gene id: 582419:TES1_RS04580
uniprot id: W0I682
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS01965
gene id: 582419:TES1_RS01965
uniprot id: W0I5T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

582419:TES1 RS03180
gene id: 582419:TES1_RS03180
uniprot id: W0I5L4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS04025
gene id: 582419:TES1_RS04025
uniprot id: W0I289
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

582419:TES1 RS10305
gene id: 582419:TES1_RS10305
uniprot id: W0I9B0
names: Similarity
messages: Belongs to the peptidase S8 family.

582419:TES1 RS00585
gene id: 582419:TES1_RS00585
uniprot id: W0I0I8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

582419:TES1 RS02685
gene id: 582419:TES1_RS02685
uniprot id: W0I1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm

582419:TES1 RS06160
gene id: 582419:TES1_RS06160
uniprot id: W0I3E4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

582419:TES1 RS06085
gene id: 582419:TES1_RS06085
uniprot id: W0I3A4
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

582419:TES1 RS00150
gene id: 582419:TES1_RS00150
uniprot id: W0I0B9
names: Similarity
messages: Belongs to the AOR/FOR family.

582419:TES1 RS03970
gene id: 582419:TES1_RS03970
uniprot id: W0I5Y1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

582419:TES1 RS00735
gene id: 582419:TES1_RS00735
uniprot id: W0I586
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

582419:TES1 RS02665
gene id: 582419:TES1_RS02665
uniprot id: W0I636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

582419:TES1 RS07200
gene id: 582419:TES1_RS07200
uniprot id: W0I7L7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS01225
gene id: 582419:TES1_RS01225
uniprot id: W0I0V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS00175
gene id: 582419:TES1_RS00175
uniprot id: W0I0C4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

582419:TES1 RS06175
gene id: 582419:TES1_RS06175
uniprot id: W0I757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

582419:TES1 RS05020
gene id: 582419:TES1_RS05020
uniprot id: W0I7A0
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

582419:TES1 RS01025
gene id: 582419:TES1_RS01025
uniprot id: W0I5D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS06835
gene id: 582419:TES1_RS06835
uniprot id: W0I3R9
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

582419:TES1 RS09905
gene id: 582419:TES1_RS09905
uniprot id: W0I9W7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

582419:TES1 RS08685
gene id: 582419:TES1_RS08685
uniprot id: W0I9E5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

582419:TES1 RS02580
gene id: 582419:TES1_RS02580
uniprot id: W0I661
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

582419:TES1 RS01050
gene id: 582419:TES1_RS01050
uniprot id: W0I5D4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS00730
gene id: 582419:TES1_RS00730
uniprot id: W0I498
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

582419:TES1 RS05290
gene id: 582419:TES1_RS05290
uniprot id: W0I7I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

582419:TES1 RS00635
gene id: 582419:TES1_RS00635
uniprot id: W0I514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS00500
gene id: 582419:TES1_RS00500
uniprot id: W0I460
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04880
gene id: 582419:TES1_RS04880
uniprot id: W0I777
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

582419:TES1 RS07240
gene id: 582419:TES1_RS07240
uniprot id: W0I8G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

582419:TES1 RS01085
gene id: 582419:TES1_RS01085
uniprot id: W0I596
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

582419:TES1 RS04845
gene id: 582419:TES1_RS04845
uniprot id: W0I773
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

582419:TES1 RS10150
gene id: 582419:TES1_RS10150
uniprot id: W0I5C1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

582419:TES1 RS08475
gene id: 582419:TES1_RS08475
uniprot id: W0I9A9
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS00550
gene id: 582419:TES1_RS00550
uniprot id: W0I470
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS01720
gene id: 582419:TES1_RS01720
uniprot id: W0I5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

582419:TES1 RS07025
gene id: 582419:TES1_RS07025
uniprot id: W0I3V0
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

582419:TES1 RS00595
gene id: 582419:TES1_RS00595
uniprot id: W0I478
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

582419:TES1 RS08775
gene id: 582419:TES1_RS08775
uniprot id: W0I4N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

582419:TES1 RS01505
gene id: 582419:TES1_RS01505
uniprot id: W0I5L7
names: Similarity
messages: Belongs to the thymidylate kinase family.

582419:TES1 RS10260
gene id: 582419:TES1_RS10260
uniprot id: W0IA67
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

582419:TES1 RS04020
gene id: 582419:TES1_RS04020
uniprot id: W0I6T1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

582419:TES1 RS09425
gene id: 582419:TES1_RS09425
uniprot id: W0I8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

582419:TES1 RS10375
gene id: 582419:TES1_RS10375
uniprot id: W0I5F9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

582419:TES1 RS01545
gene id: 582419:TES1_RS01545
uniprot id: W0I5H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

582419:TES1 RS09030
gene id: 582419:TES1_RS09030
uniprot id: W0I9G0
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

582419:TES1 RS04890
gene id: 582419:TES1_RS04890
uniprot id: W0I6D4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

582419:TES1 RS03130
gene id: 582419:TES1_RS03130
uniprot id: W0I5K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

582419:TES1 RS07845
gene id: 582419:TES1_RS07845
uniprot id: W0I8W8
names: Similarity
messages: Belongs to the FrhG family.

582419:TES1 RS05365
gene id: 582419:TES1_RS05365
uniprot id: W0I302
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

582419:TES1 RS07105
gene id: 582419:TES1_RS07105
uniprot id: W0I8I2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

582419:TES1 RS10285
gene id: 582419:TES1_RS10285
uniprot id: W0IA72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

582419:TES1 RS03825
gene id: 582419:TES1_RS03825
uniprot id: W0I6U1
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS08935
gene id: 582419:TES1_RS08935
uniprot id: W0I8M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

582419:TES1 RS02360
gene id: 582419:TES1_RS02360
uniprot id: W0I1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

582419:TES1 RS05835
gene id: 582419:TES1_RS05835
uniprot id: W0I7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

582419:TES1 RS01775
gene id: 582419:TES1_RS01775
uniprot id: W0I4Q6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

582419:TES1 RS08065
gene id: 582419:TES1_RS08065
uniprot id: W0I4E5
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS07955
gene id: 582419:TES1_RS07955
uniprot id: W0I825
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

582419:TES1 RS01170
gene id: 582419:TES1_RS01170
uniprot id: W0I0U4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

582419:TES1 RS04465
gene id: 582419:TES1_RS04465
uniprot id: W0I708
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

582419:TES1 RS08715
gene id: 582419:TES1_RS08715
uniprot id: W0I4Q9
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS08055
gene id: 582419:TES1_RS08055
uniprot id: W0I855
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

582419:TES1 RS08710
gene id: 582419:TES1_RS08710
uniprot id: W0I9F1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

582419:TES1 RS06670
gene id: 582419:TES1_RS06670
uniprot id: W0I3K0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

582419:TES1 RS09625
gene id: 582419:TES1_RS09625
uniprot id: W0I572
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS07050
gene id: 582419:TES1_RS07050
uniprot id: W0I3V4
names: Similarity
messages: Belongs to the UPF0173 family.

582419:TES1 RS09590
gene id: 582419:TES1_RS09590
uniprot id: W0I8X7
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

582419:TES1 RS02085
gene id: 582419:TES1_RS02085
uniprot id: W0I4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

582419:TES1 RS01110
gene id: 582419:TES1_RS01110
uniprot id: W0I5A1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

582419:TES1 RS04615
gene id: 582419:TES1_RS04615
uniprot id: W0I770
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

582419:TES1 RS00725
gene id: 582419:TES1_RS00725
uniprot id: W0I0G5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

582419:TES1 RS02950
gene id: 582419:TES1_RS02950
uniprot id: W0I5H4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

582419:TES1 RS10370
gene id: 582419:TES1_RS10370
uniprot id: W0IA43
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

582419:TES1 RS00930
gene id: 582419:TES1_RS00930
uniprot id: W0I0Q0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS10335
gene id: 582419:TES1_RS10335
uniprot id: W0IA82
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS09535
gene id: 582419:TES1_RS09535
uniprot id: W0I8W6
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS05955
gene id: 582419:TES1_RS05955
uniprot id: W0I383
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

582419:TES1 RS02540
gene id: 582419:TES1_RS02540
uniprot id: W0I607
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

582419:TES1 RS03615
gene id: 582419:TES1_RS03615
uniprot id: W0I242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

582419:TES1 RS02995
gene id: 582419:TES1_RS02995
uniprot id: W0I1R4
names: Similarity
messages: Belongs to the RutC family.

582419:TES1 RS01235
gene id: 582419:TES1_RS01235
uniprot id: W0I0R1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

582419:TES1 RS08880
gene id: 582419:TES1_RS08880
uniprot id: W0I4P6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

582419:TES1 RS08545
gene id: 582419:TES1_RS08545
uniprot id: W0I8F4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

582419:TES1 RS01075
gene id: 582419:TES1_RS01075
uniprot id: W0I5D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

582419:TES1 RS09170
gene id: 582419:TES1_RS09170
uniprot id: W0I4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

582419:TES1 RS10065
gene id: 582419:TES1_RS10065
uniprot id: W0I9Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS00285
gene id: 582419:TES1_RS00285
uniprot id: W0I0A3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

582419:TES1 RS07270
gene id: 582419:TES1_RS07270
uniprot id: W0I3V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

582419:TES1 RS01990
gene id: 582419:TES1_RS01990
uniprot id: W0I5U0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

582419:TES1 RS04100
gene id: 582419:TES1_RS04100
uniprot id: W0I6U3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS10265
gene id: 582419:TES1_RS10265
uniprot id: W0I5I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

582419:TES1 RS06010
gene id: 582419:TES1_RS06010
uniprot id: W0I392
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

582419:TES1 RS01430
gene id: 582419:TES1_RS01430
uniprot id: W0I0Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

582419:TES1 RS09110
gene id: 582419:TES1_RS09110
uniprot id: W0I4X3
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01095
gene id: 582419:TES1_RS01095
uniprot id: W0I4F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

582419:TES1 RS06485
gene id: 582419:TES1_RS06485
uniprot id: W0I3G7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

582419:TES1 RS06840
gene id: 582419:TES1_RS06840
uniprot id: W0I894
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

582419:TES1 RS08295
gene id: 582419:TES1_RS08295
uniprot id: W0I4F5
names: Similarity
messages: Belongs to the HsdR family.

582419:TES1 RS05775
gene id: 582419:TES1_RS05775
uniprot id: W0I6Z4
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

582419:TES1 RS04000
gene id: 582419:TES1_RS04000
uniprot id: W0I286
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

582419:TES1 RS00495
gene id: 582419:TES1_RS00495
uniprot id: W0I0C9
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS08100
gene id: 582419:TES1_RS08100
uniprot id: W0I4D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

582419:TES1 RS08130
gene id: 582419:TES1_RS08130
uniprot id: W0I884
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

582419:TES1 RS03455
gene id: 582419:TES1_RS03455
uniprot id: W0I6N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

582419:TES1 RS01090
gene id: 582419:TES1_RS01090
uniprot id: W0I0N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

582419:TES1 RS04745
gene id: 582419:TES1_RS04745
uniprot id: W0I754
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

582419:TES1 RS10235
gene id: 582419:TES1_RS10235
uniprot id: W0IA66
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

582419:TES1 RS01180
gene id: 582419:TES1_RS01180
uniprot id: W0I0Q1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

582419:TES1 RS04560
gene id: 582419:TES1_RS04560
uniprot id: W0I762
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04375
gene id: 582419:TES1_RS04375
uniprot id: W0I735
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

582419:TES1 RS02300
gene id: 582419:TES1_RS02300
uniprot id: W0I512
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

582419:TES1 RS08145
gene id: 582419:TES1_RS08145
uniprot id: W0I4H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

582419:TES1 RS04895
gene id: 582419:TES1_RS04895
uniprot id: W0I7B0
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS08070
gene id: 582419:TES1_RS08070
uniprot id: W0I8Z8
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS06350
gene id: 582419:TES1_RS06350
uniprot id: W0I809
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02335
gene id: 582419:TES1_RS02335
uniprot id: W0I1F6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

582419:TES1 RS10400
gene id: 582419:TES1_RS10400
uniprot id: W0I9D4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

582419:TES1 RS08990
gene id: 582419:TES1_RS08990
uniprot id: W0I9J8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582419:TES1 RS05360
gene id: 582419:TES1_RS05360
uniprot id: W0I7J2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

582419:TES1 RS07665
gene id: 582419:TES1_RS07665
uniprot id: W0I7W2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS00975
gene id: 582419:TES1_RS00975
uniprot id: W0I5C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

582419:TES1 RS05655
gene id: 582419:TES1_RS05655
uniprot id: W0I339
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

582419:TES1 RS06310
gene id: 582419:TES1_RS06310
uniprot id: W0I775
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS07940
gene id: 582419:TES1_RS07940
uniprot id: W0I4B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

582419:TES1 RS05230
gene id: 582419:TES1_RS05230
uniprot id: W0I2U9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

582419:TES1 RS02815
gene id: 582419:TES1_RS02815
uniprot id: W0I1P0
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

582419:TES1 RS01920
gene id: 582419:TES1_RS01920
uniprot id: W0I172
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

582419:TES1 RS07145
gene id: 582419:TES1_RS07145
uniprot id: W0I3T5
names: Subcellular Location Annotation
messages: Cell membrane

582419:TES1 RS09790
gene id: 582419:TES1_RS09790
uniprot id: W0I913
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

582419:TES1 RS07730
gene id: 582419:TES1_RS07730
uniprot id: W0I8Q8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS09520
gene id: 582419:TES1_RS09520
uniprot id: W0I552
names: Similarity
messages: Belongs to the AOR/FOR family.

582419:TES1 RS00710
gene id: 582419:TES1_RS00710
uniprot id: W0I581
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04775
gene id: 582419:TES1_RS04775
uniprot id: W0I2L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

582419:TES1 RS07720
gene id: 582419:TES1_RS07720
uniprot id: W0I8U3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS01285
gene id: 582419:TES1_RS01285
uniprot id: W0I5C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal MetE family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.

582419:TES1 RS08645
gene id: 582419:TES1_RS08645
uniprot id: W0I8H4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

582419:TES1 RS06110
gene id: 582419:TES1_RS06110
uniprot id: W0I7W3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

582419:TES1 RS08975
gene id: 582419:TES1_RS08975
uniprot id: W0I9F2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

582419:TES1 RS01100
gene id: 582419:TES1_RS01100
uniprot id: W0I5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

582419:TES1 RS02310
gene id: 582419:TES1_RS02310
uniprot id: W0I1F1
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

582419:TES1 RS04990
gene id: 582419:TES1_RS04990
uniprot id: W0I2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

582419:TES1 RS08905
gene id: 582419:TES1_RS08905
uniprot id: W0I4P9
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

582419:TES1 RS02130
gene id: 582419:TES1_RS02130
uniprot id: W0I179
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

582419:TES1 RS08845
gene id: 582419:TES1_RS08845
uniprot id: W0I9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS10535
gene id: 582419:TES1_RS10535
uniprot id: W0IAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS04360
gene id: 582419:TES1_RS04360
uniprot id: W0I6Y8
names: Similarity
messages: Belongs to the MoaB/Mog family.

582419:TES1 RS01955
gene id: 582419:TES1_RS01955
uniprot id: W0I143
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

582419:TES1 RS07700
gene id: 582419:TES1_RS07700
uniprot id: W0I471
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS03525
gene id: 582419:TES1_RS03525
uniprot id: W0I5R1
names: Similarity
messages: Belongs to the RuvB family.

582419:TES1 RS07185
gene id: 582419:TES1_RS07185
uniprot id: W0I3X6
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02965
gene id: 582419:TES1_RS02965
uniprot id: W0I6A9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

582419:TES1 RS10295
gene id: 582419:TES1_RS10295
uniprot id: W0IA30
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

582419:TES1 RS03555
gene id: 582419:TES1_RS03555
uniprot id: W0I6Q3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

582419:TES1 RS06275
gene id: 582419:TES1_RS06275
uniprot id: W0I7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

582419:TES1 RS01850
gene id: 582419:TES1_RS01850
uniprot id: W0I120
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

582419:TES1 RS06885
gene id: 582419:TES1_RS06885
uniprot id: W0I7G8
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

582419:TES1 RS01230
gene id: 582419:TES1_RS01230
uniprot id: W0I5C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

582419:TES1 RS08210
gene id: 582419:TES1_RS08210
uniprot id: W0I4E4
names: Similarity
messages: Belongs to the class-I fumarase family.

582419:TES1 RS02635
gene id: 582419:TES1_RS02635
uniprot id: W0I1L4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

582419:TES1 RS03405
gene id: 582419:TES1_RS03405
uniprot id: W0I6M6
names: Similarity
messages: Belongs to the UPF0127 family.

582419:TES1 RS02945
gene id: 582419:TES1_RS02945
uniprot id: W0I1Q7
names: Similarity
messages: Belongs to the HerA family.

582419:TES1 RS07970
gene id: 582419:TES1_RS07970
uniprot id: W0I8V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

582419:TES1 RS01590
gene id: 582419:TES1_RS01590
uniprot id: W0I116
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

582419:TES1 RS07210
gene id: 582419:TES1_RS07210
uniprot id: W0I3Y0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS04225
gene id: 582419:TES1_RS04225
uniprot id: W0I705
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

582419:TES1 RS04270
gene id: 582419:TES1_RS04270
uniprot id: W0I630
names: Cofactor
messages: Binds 1 zinc ion per subunit.

582419:TES1 RS02475
gene id: 582419:TES1_RS02475
uniprot id: W0I551
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

582419:TES1 RS06315
gene id: 582419:TES1_RS06315
uniprot id: W0I843
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS07140
gene id: 582419:TES1_RS07140
uniprot id: W0I8E7
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS00695
gene id: 582419:TES1_RS00695
uniprot id: W0I522
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

582419:TES1 RS01705
gene id: 582419:TES1_RS01705
uniprot id: W0I4P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

582419:TES1 RS08500
gene id: 582419:TES1_RS08500
uniprot id: W0I9B3
names: Similarity
messages: Belongs to the UPF0147 family.

582419:TES1 RS00950
gene id: 582419:TES1_RS00950
uniprot id: W0I5B8
names: Similarity
messages: Belongs to the ZPR1 family.

582419:TES1 RS06225
gene id: 582419:TES1_RS06225
uniprot id: W0I3C4
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01300
gene id: 582419:TES1_RS01300
uniprot id: W0I5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

582419:TES1 RS09635
gene id: 582419:TES1_RS09635
uniprot id: W0I523
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS04475
gene id: 582419:TES1_RS04475
uniprot id: W0I665
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

582419:TES1 RS07215
gene id: 582419:TES1_RS07215
uniprot id: W0I8G2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS08810
gene id: 582419:TES1_RS08810
uniprot id: W0I9G8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

582419:TES1 RS07635
gene id: 582419:TES1_RS07635
uniprot id: W0I417
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS03470
gene id: 582419:TES1_RS03470
uniprot id: W0I1Y4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

582419:TES1 RS06515
gene id: 582419:TES1_RS06515
uniprot id: W0I7A8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582419:TES1 RS01365
gene id: 582419:TES1_RS01365
uniprot id: W0I0T8
names: Similarity
messages: Belongs to the UPF0440 family.

582419:TES1 RS01160
gene id: 582419:TES1_RS01160
uniprot id: W0I5F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

582419:TES1 RS05005
gene id: 582419:TES1_RS05005
uniprot id: W0I6H0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

582419:TES1 RS03655
gene id: 582419:TES1_RS03655
uniprot id: W0I219
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS05760
gene id: 582419:TES1_RS05760
uniprot id: W0I385
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

582419:TES1 RS06215
gene id: 582419:TES1_RS06215
uniprot id: W0I7Y3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the N-terminal section; belongs to the MobA family.

582419:TES1 RS01400
gene id: 582419:TES1_RS01400
uniprot id: W0I5J8
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

582419:TES1 RS03895
gene id: 582419:TES1_RS03895
uniprot id: W0I5W6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

582419:TES1 RS04230
gene id: 582419:TES1_RS04230
uniprot id: W0I2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS01200
gene id: 582419:TES1_RS01200
uniprot id: W0I0U9
names: Similarity
messages: Belongs to the enolase family.

582419:TES1 RS02790
gene id: 582419:TES1_RS02790
uniprot id: W0I1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS06650
gene id: 582419:TES1_RS06650
uniprot id: W0I7C6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS06570
gene id: 582419:TES1_RS06570
uniprot id: W0I3I1
names: Similarity
messages: Belongs to the DEAD box helicase family.

582419:TES1 RS05660
gene id: 582419:TES1_RS05660
uniprot id: W0I6X8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS00470
gene id: 582419:TES1_RS00470
uniprot id: W0I0C6
names: Similarity
messages: Belongs to the HupF/HypC family.

582419:TES1 RS10390
gene id: 582419:TES1_RS10390
uniprot id: W0I5L3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

582419:TES1 RS04075
gene id: 582419:TES1_RS04075
uniprot id: W0I6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
messages: Cell membrane
messages: Membrane

582419:TES1 RS01255
gene id: 582419:TES1_RS01255
uniprot id: W0I5C5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

582419:TES1 RS07535
gene id: 582419:TES1_RS07535
uniprot id: W0I7T3
names: Similarity
messages: Belongs to the peptidase U62 family.

582419:TES1 RS01460
gene id: 582419:TES1_RS01460
uniprot id: W0I5G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

582419:TES1 RS01985
gene id: 582419:TES1_RS01985
uniprot id: W0I4U5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

582419:TES1 RS01435
gene id: 582419:TES1_RS01435
uniprot id: W0I5F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

582419:TES1 RS00205
gene id: 582419:TES1_RS00205
uniprot id: W0I4U4
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

582419:TES1 RS02830
gene id: 582419:TES1_RS02830
uniprot id: W0I6D2
names: Similarity
messages: Belongs to the UPF0166 family.

582419:TES1 RS02695
gene id: 582419:TES1_RS02695
uniprot id: W0I1L0
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
messages: Contains two alpha-helical subdomains, with the 8-oxoguanine binding site located in a cleft at their interface. Contains a helix-hairpin-helix (HhH) structural motif and a Gly/Pro-rich sequence followed by a conserved Asp (HhH-GPD motif).
messages: DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS08190
gene id: 582419:TES1_RS08190
uniprot id: W0I965
names: Similarity
messages: Belongs to the UPF0111 family.

582419:TES1 RS03245
gene id: 582419:TES1_RS03245
uniprot id: W0I6F8
names: Similarity
messages: Belongs to the UPF0248 family.

582419:TES1 RS03965
gene id: 582419:TES1_RS03965
uniprot id: W0I280
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

582419:TES1 RS06040
gene id: 582419:TES1_RS06040
uniprot id: W0I737
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

582419:TES1 RS05310
gene id: 582419:TES1_RS05310
uniprot id: W0I6N5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

582419:TES1 RS10545
gene id: 582419:TES1_RS10545
uniprot id: W0IA79
names: Similarity
messages: Belongs to the UPF0175 family.

582419:TES1 RS02885
gene id: 582419:TES1_RS02885
uniprot id: W0I1S7
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

582419:TES1 RS00670
gene id: 582419:TES1_RS00670
uniprot id: W0I518
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

582419:TES1 RS00535
gene id: 582419:TES1_RS00535
uniprot id: W0I0H6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS07745
gene id: 582419:TES1_RS07745
uniprot id: W0I8U7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS06800
gene id: 582419:TES1_RS06800
uniprot id: W0I7F3
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

582419:TES1 RS00425
gene id: 582419:TES1_RS00425
uniprot id: W0I449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

582419:TES1 RS02915
gene id: 582419:TES1_RS02915
uniprot id: W0I6A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

582419:TES1 RS10665
gene id: 582419:TES1_RS10665
uniprot id: W0I9I9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

582419:TES1 RS00985
gene id: 582419:TES1_RS00985
uniprot id: W0I576
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

582419:TES1 RS01265
gene id: 582419:TES1_RS01265
uniprot id: W0I4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

582419:TES1 RS05545
gene id: 582419:TES1_RS05545
uniprot id: W0I356
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS04545
gene id: 582419:TES1_RS04545
uniprot id: W0I722
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS07035
gene id: 582419:TES1_RS07035
uniprot id: W0I3R5
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

582419:TES1 RS02730
gene id: 582419:TES1_RS02730
uniprot id: W0I1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS04800
gene id: 582419:TES1_RS04800
uniprot id: W0I2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

582419:TES1 RS02565
gene id: 582419:TES1_RS02565
uniprot id: W0I613
names: Similarity
messages: Belongs to the P(II) protein family.

582419:TES1 RS01655
gene id: 582419:TES1_RS01655
uniprot id: W0I4P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

582419:TES1 RS05840
gene id: 582419:TES1_RS05840
uniprot id: W0I396
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

582419:TES1 RS01040
gene id: 582419:TES1_RS01040
uniprot id: W0I0M6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

582419:TES1 RS02425
gene id: 582419:TES1_RS02425
uniprot id: W0I540
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

582419:TES1 RS10080
gene id: 582419:TES1_RS10080
uniprot id: W0IA42
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

582419:TES1 RS00760
gene id: 582419:TES1_RS00760
uniprot id: W0I590
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

582419:TES1 RS02925
gene id: 582419:TES1_RS02925
uniprot id: W0I5H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

582419:TES1 RS08310
gene id: 582419:TES1_RS08310
uniprot id: W0I983
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

582419:TES1 RS03535
gene id: 582419:TES1_RS03535
uniprot id: W0I228
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

582419:TES1 RS10380
gene id: 582419:TES1_RS10380
uniprot id: W0I9C9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS04260
gene id: 582419:TES1_RS04260
uniprot id: W0I6W6
names: Similarity
messages: Belongs to the peptidase U62 family.

582419:TES1 RS05460
gene id: 582419:TES1_RS05460
uniprot id: W0I7N8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

582419:TES1 RS07830
gene id: 582419:TES1_RS07830
uniprot id: W0I8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

582419:TES1 RS05920
gene id: 582419:TES1_RS05920
uniprot id: W0I3A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

582419:TES1 RS06645
gene id: 582419:TES1_RS06645
uniprot id: W0I3J5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

582419:TES1 RS07475
gene id: 582419:TES1_RS07475
uniprot id: W0I3Z0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

582419:TES1 RS09720
gene id: 582419:TES1_RS09720
uniprot id: W0I9X8
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS06505
gene id: 582419:TES1_RS06505
uniprot id: W0I837
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04730
gene id: 582419:TES1_RS04730
uniprot id: W0I6A4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS08630
gene id: 582419:TES1_RS08630
uniprot id: W0I4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

582419:TES1 RS00080
gene id: 582419:TES1_RS00080
uniprot id: W0I041
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

582419:TES1 RS04050
gene id: 582419:TES1_RS04050
uniprot id: W0I294
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

582419:TES1 RS06610
gene id: 582419:TES1_RS06610
uniprot id: W0I890
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

582419:TES1 RS09410
gene id: 582419:TES1_RS09410
uniprot id: W0I531
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS00620
gene id: 582419:TES1_RS00620
uniprot id: W0I482
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

582419:TES1 RS03135
gene id: 582419:TES1_RS03135
uniprot id: W0I6I4
names: Similarity
messages: Belongs to the glutaredoxin family.

582419:TES1 RS03605
gene id: 582419:TES1_RS03605
uniprot id: W0I6R0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

582419:TES1 RS02785
gene id: 582419:TES1_RS02785
uniprot id: W0I680
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

582419:TES1 RS01710
gene id: 582419:TES1_RS01710
uniprot id: W0I5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

582419:TES1 RS08550
gene id: 582419:TES1_RS08550
uniprot id: W0I9C1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

582419:TES1 RS01725
gene id: 582419:TES1_RS01725
uniprot id: W0I100
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

582419:TES1 RS06300
gene id: 582419:TES1_RS06300
uniprot id: W0I7Z9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS01455
gene id: 582419:TES1_RS01455
uniprot id: W0I0Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

582419:TES1 RS06480
gene id: 582419:TES1_RS06480
uniprot id: W0I831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

582419:TES1 RS03915
gene id: 582419:TES1_RS03915
uniprot id: W0I269
names: Similarity
messages: Belongs to the arginase family.

582419:TES1 RS09185
gene id: 582419:TES1_RS09185
uniprot id: W0I4Y6
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

582419:TES1 RS02810
gene id: 582419:TES1_RS02810
uniprot id: W0I684
names: Similarity
messages: Belongs to the CinA family.

582419:TES1 RS01175
gene id: 582419:TES1_RS01175
uniprot id: W0I5B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

582419:TES1 RS04670
gene id: 582419:TES1_RS04670
uniprot id: W0I2M8
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02215
gene id: 582419:TES1_RS02215
uniprot id: W0I5U3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

582419:TES1 RS04495
gene id: 582419:TES1_RS04495
uniprot id: W0I2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

582419:TES1 RS02870
gene id: 582419:TES1_RS02870
uniprot id: W0I1P8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

582419:TES1 RS05650
gene id: 582419:TES1_RS05650
uniprot id: W0I7N6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

582419:TES1 RS01465
gene id: 582419:TES1_RS01465
uniprot id: W0I0V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

582419:TES1 RS01245
gene id: 582419:TES1_RS01245
uniprot id: W0I5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

582419:TES1 RS01475
gene id: 582419:TES1_RS01475
uniprot id: W0I5L1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS09585
gene id: 582419:TES1_RS09585
uniprot id: W0I513
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

582419:TES1 RS09385
gene id: 582419:TES1_RS09385
uniprot id: W0I526
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01115
gene id: 582419:TES1_RS01115
uniprot id: W0I0P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

582419:TES1 RS04910
gene id: 582419:TES1_RS04910
uniprot id: W0I2N9
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS08950
gene id: 582419:TES1_RS08950
uniprot id: W0I9E7
names: Similarity
messages: Belongs to the UPF0273 family.

582419:TES1 RS10280
gene id: 582419:TES1_RS10280
uniprot id: W0I9A5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

582419:TES1 RS02955
gene id: 582419:TES1_RS02955
uniprot id: W0I6F2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

582419:TES1 RS05790
gene id: 582419:TES1_RS05790
uniprot id: W0I7R0
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS06990
gene id: 582419:TES1_RS06990
uniprot id: W0I8G5
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

582419:TES1 RS07220
gene id: 582419:TES1_RS07220
uniprot id: W0I3U8
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

582419:TES1 RS02470
gene id: 582419:TES1_RS02470
uniprot id: W0I1F4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

582419:TES1 RS09765
gene id: 582419:TES1_RS09765
uniprot id: W0I909
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

582419:TES1 RS02445
gene id: 582419:TES1_RS02445
uniprot id: W0I1F0
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS08195
gene id: 582419:TES1_RS08195
uniprot id: W0I4I0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

582419:TES1 RS05630
gene id: 582419:TES1_RS05630
uniprot id: W0I337
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

582419:TES1 RS01795
gene id: 582419:TES1_RS01795
uniprot id: W0I110
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

582419:TES1 RS07520
gene id: 582419:TES1_RS07520
uniprot id: W0I435
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

582419:TES1 RS03640
gene id: 582419:TES1_RS03640
uniprot id: W0I6R4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

582419:TES1 RS02585
gene id: 582419:TES1_RS02585
uniprot id: W0I1K3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

582419:TES1 RS06155
gene id: 582419:TES1_RS06155
uniprot id: W0I815
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

582419:TES1 RS10385
gene id: 582419:TES1_RS10385
uniprot id: W0IA92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

582419:TES1 RS08030
gene id: 582419:TES1_RS08030
uniprot id: W0I840
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

582419:TES1 RS03705
gene id: 582419:TES1_RS03705
uniprot id: W0I230
names: Subunit
messages: Homodimer.

582419:TES1 RS00545
gene id: 582419:TES1_RS00545
uniprot id: W0I0D6
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS09985
gene id: 582419:TES1_RS09985
uniprot id: W0I9Y1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

582419:TES1 RS06245
gene id: 582419:TES1_RS06245
uniprot id: W0I7Y9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

582419:TES1 RS07985
gene id: 582419:TES1_RS07985
uniprot id: W0I8Z2
names: Similarity
messages: Belongs to the acylphosphatase family.

582419:TES1 RS06285
gene id: 582419:TES1_RS06285
uniprot id: W0I772
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

582419:TES1 RS02910
gene id: 582419:TES1_RS02910
uniprot id: W0I1T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

582419:TES1 RS00315
gene id: 582419:TES1_RS00315
uniprot id: W0I0A6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

582419:TES1 RS01320
gene id: 582419:TES1_RS01320
uniprot id: W0I4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

582419:TES1 RS05570
gene id: 582419:TES1_RS05570
uniprot id: W0I358
names: Similarity
messages: Belongs to the peptidase C56 family.

582419:TES1 RS02430
gene id: 582419:TES1_RS02430
uniprot id: W0I635
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

582419:TES1 RS07555
gene id: 582419:TES1_RS07555
uniprot id: W0I403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS06400
gene id: 582419:TES1_RS06400
uniprot id: W0I818
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbohydrate kinase PfkC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
messages: Cytoplasm

582419:TES1 RS03900
gene id: 582419:TES1_RS03900
uniprot id: W0I6V4
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

582419:TES1 RS09655
gene id: 582419:TES1_RS09655
uniprot id: W0I9R7
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01840
gene id: 582419:TES1_RS01840
uniprot id: W0I157
names: Similarity
messages: Belongs to the FUN14 family.

582419:TES1 RS02370
gene id: 582419:TES1_RS02370
uniprot id: W0I1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

582419:TES1 RS08365
gene id: 582419:TES1_RS08365
uniprot id: W0I8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS08995
gene id: 582419:TES1_RS08995
uniprot id: W0I4V6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

582419:TES1 RS05450
gene id: 582419:TES1_RS05450
uniprot id: W0I312
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

582419:TES1 RS00655
gene id: 582419:TES1_RS00655
uniprot id: W0I485
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP-dependent glucokinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
messages: Cytoplasm

582419:TES1 RS08700
gene id: 582419:TES1_RS08700
uniprot id: W0I4L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS01930
gene id: 582419:TES1_RS01930
uniprot id: W0I138
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS09925
gene id: 582419:TES1_RS09925
uniprot id: W0I5C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

582419:TES1 RS08370
gene id: 582419:TES1_RS08370
uniprot id: W0I992
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS07755
gene id: 582419:TES1_RS07755
uniprot id: W0I8R2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS09530
gene id: 582419:TES1_RS09530
uniprot id: W0I503
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

582419:TES1 RS00895
gene id: 582419:TES1_RS00895
uniprot id: W0I4B9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

582419:TES1 RS08535
gene id: 582419:TES1_RS08535
uniprot id: W0I972
names: Similarity
messages: Belongs to the UPF0045 family.

582419:TES1 RS05265
gene id: 582419:TES1_RS05265
uniprot id: W0I7H9
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS03100
gene id: 582419:TES1_RS03100
uniprot id: W0I1T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

582419:TES1 RS05445
gene id: 582419:TES1_RS05445
uniprot id: W0I7J8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

582419:TES1 RS03540
gene id: 582419:TES1_RS03540
uniprot id: W0I6K3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

582419:TES1 RS05455
gene id: 582419:TES1_RS05455
uniprot id: W0I6T9
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS10275
gene id: 582419:TES1_RS10275
uniprot id: W0I5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

582419:TES1 RS06385
gene id: 582419:TES1_RS06385
uniprot id: W0I789
names: Similarity
messages: Belongs to the SfsA family.

582419:TES1 RS05890
gene id: 582419:TES1_RS05890
uniprot id: W0I7W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

582419:TES1 RS03050
gene id: 582419:TES1_RS03050
uniprot id: W0I5J1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

582419:TES1 RS01325
gene id: 582419:TES1_RS01325
uniprot id: W0I5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

582419:TES1 RS03195
gene id: 582419:TES1_RS03195
uniprot id: W0I6F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

582419:TES1 RS01035
gene id: 582419:TES1_RS01035
uniprot id: W0I587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

582419:TES1 RS01360
gene id: 582419:TES1_RS01360
uniprot id: W0I5E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

582419:TES1 RS08250
gene id: 582419:TES1_RS08250
uniprot id: W0I4I8
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02330
gene id: 582419:TES1_RS02330
uniprot id: W0I614
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

582419:TES1 RS02725
gene id: 582419:TES1_RS02725
uniprot id: W0I6B6
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS08890
gene id: 582419:TES1_RS08890
uniprot id: W0I9I2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

582419:TES1 RS06910
gene id: 582419:TES1_RS06910
uniprot id: W0I7H3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS08900
gene id: 582419:TES1_RS08900
uniprot id: W0I9D7
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

582419:TES1 RS01145
gene id: 582419:TES1_RS01145
uniprot id: W0I5A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

582419:TES1 RS04400
gene id: 582419:TES1_RS04400
uniprot id: W0I652
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

582419:TES1 RS06585
gene id: 582419:TES1_RS06585
uniprot id: W0I885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

582419:TES1 RS03035
gene id: 582419:TES1_RS03035
uniprot id: W0I1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

582419:TES1 RS09420
gene id: 582419:TES1_RS09420
uniprot id: W0I4Y3
names: Similarity
messages: Belongs to the GbsR family.

582419:TES1 RS03975
gene id: 582419:TES1_RS03975
uniprot id: W0I6W7
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

582419:TES1 RS04860
gene id: 582419:TES1_RS04860
uniprot id: W0I6C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS02825
gene id: 582419:TES1_RS02825
uniprot id: W0I5F0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS00260
gene id: 582419:TES1_RS00260
uniprot id: W0I098
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

582419:TES1 RS04915
gene id: 582419:TES1_RS04915
uniprot id: W0I6E0
names: Similarity
messages: Belongs to the UPF0145 family.

582419:TES1 RS06880
gene id: 582419:TES1_RS06880
uniprot id: W0I3N9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

582419:TES1 RS07480
gene id: 582419:TES1_RS07480
uniprot id: W0I7S2
names: Similarity
messages: Belongs to the BtpA family.

582419:TES1 RS04325
gene id: 582419:TES1_RS04325
uniprot id: W0I725
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

582419:TES1 RS03570
gene id: 582419:TES1_RS03570
uniprot id: W0I203
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

582419:TES1 RS08930
gene id: 582419:TES1_RS08930
uniprot id: W0I4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

582419:TES1 RS03465
gene id: 582419:TES1_RS03465
uniprot id: W0I6I8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

582419:TES1 RS04655
gene id: 582419:TES1_RS04655
uniprot id: W0I2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

582419:TES1 RS03460
gene id: 582419:TES1_RS03460
uniprot id: W0I214
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582419:TES1 RS02120
gene id: 582419:TES1_RS02120
uniprot id: W0I1B2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

582419:TES1 RS01305
gene id: 582419:TES1_RS01305
uniprot id: W0I0W7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

582419:TES1 RS02795
gene id: 582419:TES1_RS02795
uniprot id: W0I5E5
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01730
gene id: 582419:TES1_RS01730
uniprot id: W0I4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS01980
gene id: 582419:TES1_RS01980
uniprot id: W0I148
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04930
gene id: 582419:TES1_RS04930
uniprot id: W0I2S4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

582419:TES1 RS00320
gene id: 582419:TES1_RS00320
uniprot id: W0I432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

582419:TES1 RS00700
gene id: 582419:TES1_RS00700
uniprot id: W0I0G1
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS07660
gene id: 582419:TES1_RS07660
uniprot id: W0I422
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS10430
gene id: 582419:TES1_RS10430
uniprot id: W0I5M4
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

582419:TES1 RS10420
gene id: 582419:TES1_RS10420
uniprot id: W0I5H1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

582419:TES1 RS08230
gene id: 582419:TES1_RS08230
uniprot id: W0I922
names: Similarity
messages: Belongs to the class-I fumarase family.

582419:TES1 RS05550
gene id: 582419:TES1_RS05550
uniprot id: W0I7M3
names: Similarity
messages: Belongs to the proline racemase family.

582419:TES1 RS07605
gene id: 582419:TES1_RS07605
uniprot id: W0I8N3
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS01105
gene id: 582419:TES1_RS01105
uniprot id: W0I0T4
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS09835
gene id: 582419:TES1_RS09835
uniprot id: W0I563
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

582419:TES1 RS10530
gene id: 582419:TES1_RS10530
uniprot id: W0I9G1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

582419:TES1 RS02480
gene id: 582419:TES1_RS02480
uniprot id: W0I644
names: Similarity
messages: Belongs to the aspartokinase family.

582419:TES1 RS02735
gene id: 582419:TES1_RS02735
uniprot id: W0I675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS04920
gene id: 582419:TES1_RS04920
uniprot id: W0I7B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

582419:TES1 RS00600
gene id: 582419:TES1_RS00600
uniprot id: W0I565
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

582419:TES1 RS10245
gene id: 582419:TES1_RS10245
uniprot id: W0IA22
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

582419:TES1 RS10610
gene id: 582419:TES1_RS10610
uniprot id: W0I9H8
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02660
gene id: 582419:TES1_RS02660
uniprot id: W0I1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

582419:TES1 RS02700
gene id: 582419:TES1_RS02700
uniprot id: W0I5B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

582419:TES1 RS08125
gene id: 582419:TES1_RS08125
uniprot id: W0I4D5
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

582419:TES1 RS05905
gene id: 582419:TES1_RS05905
uniprot id: W0I376
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

582419:TES1 RS01485
gene id: 582419:TES1_RS01485
uniprot id: W0I0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

582419:TES1 RS09015
gene id: 582419:TES1_RS09015
uniprot id: W0I8N1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582419:TES1 RS07735
gene id: 582419:TES1_RS07735
uniprot id: W0I437
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS08420
gene id: 582419:TES1_RS08420
uniprot id: W0I9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS02680
gene id: 582419:TES1_RS02680
uniprot id: W0I685
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

582419:TES1 RS07565
gene id: 582419:TES1_RS07565
uniprot id: W0I8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

582419:TES1 RS02090
gene id: 582419:TES1_RS02090
uniprot id: W0I5W4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

582419:TES1 RS08470
gene id: 582419:TES1_RS08470
uniprot id: W0I8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS00190
gene id: 582419:TES1_RS00190
uniprot id: W0I411
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

582419:TES1 RS04135
gene id: 582419:TES1_RS04135
uniprot id: W0I610
names: Similarity
messages: Belongs to the UPF0212 family.

582419:TES1 RS02165
gene id: 582419:TES1_RS02165
uniprot id: W0I1C2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

582419:TES1 RS06555
gene id: 582419:TES1_RS06555
uniprot id: W0I845
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

582419:TES1 RS06895
gene id: 582419:TES1_RS06895
uniprot id: W0I3S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS03745
gene id: 582419:TES1_RS03745
uniprot id: W0I267
names: Similarity
messages: Belongs to the AOR/FOR family.

582419:TES1 RS02895
gene id: 582419:TES1_RS02895
uniprot id: W0I1Q0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

582419:TES1 RS01740
gene id: 582419:TES1_RS01740
uniprot id: W0I142
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS04650
gene id: 582419:TES1_RS04650
uniprot id: W0I742
names: Subunit
messages: Homotetramer.

582419:TES1 RS01015
gene id: 582419:TES1_RS01015
uniprot id: W0I0M1
names: Similarity
messages: Belongs to the SUI1 family.

582419:TES1 RS06875
gene id: 582419:TES1_RS06875
uniprot id: W0I899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

582419:TES1 RS01065
gene id: 582419:TES1_RS01065
uniprot id: W0I0N0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

582419:TES1 RS06965
gene id: 582419:TES1_RS06965
uniprot id: W0I8G1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

582419:TES1 RS02025
gene id: 582419:TES1_RS02025
uniprot id: W0I5Q7
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS06120
gene id: 582419:TES1_RS06120
uniprot id: W0I749
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

582419:TES1 RS08940
gene id: 582419:TES1_RS08940
uniprot id: W0I9J2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

582419:TES1 RS00900
gene id: 582419:TES1_RS00900
uniprot id: W0I5A9
names: Subcellular Location Annotation
messages: Nucleus

582419:TES1 RS09665
gene id: 582419:TES1_RS09665
uniprot id: W0I8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

582419:TES1 RS02610
gene id: 582419:TES1_RS02610
uniprot id: W0I1K8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

582419:TES1 RS06235
gene id: 582419:TES1_RS06235
uniprot id: W0I830
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS04280
gene id: 582419:TES1_RS04280
uniprot id: W0I2F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

582419:TES1 RS03715
gene id: 582419:TES1_RS03715
uniprot id: W0I6S5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

582419:TES1 RS07250
gene id: 582419:TES1_RS07250
uniprot id: W0I7M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

582419:TES1 RS01700
gene id: 582419:TES1_RS01700
uniprot id: W0I0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

582419:TES1 RS05975
gene id: 582419:TES1_RS05975
uniprot id: W0I7U3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

582419:TES1 RS07620
gene id: 582419:TES1_RS07620
uniprot id: W0I8S4
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

582419:TES1 RS06535
gene id: 582419:TES1_RS06535
uniprot id: W0I3H5
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02410
gene id: 582419:TES1_RS02410
uniprot id: W0I1H1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

582419:TES1 RS04760
gene id: 582419:TES1_RS04760
uniprot id: W0I790
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS09620
gene id: 582419:TES1_RS09620
uniprot id: W0I9V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

582419:TES1 RS00465
gene id: 582419:TES1_RS00465
uniprot id: W0I4Y4
names: Similarity
messages: Belongs to the HypD family.

582419:TES1 RS01535
gene id: 582419:TES1_RS01535
uniprot id: W0I5M1
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

582419:TES1 RS08695
gene id: 582419:TES1_RS08695
uniprot id: W0I999
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

582419:TES1 RS05340
gene id: 582419:TES1_RS05340
uniprot id: W0I2Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

582419:TES1 RS03150
gene id: 582419:TES1_RS03150
uniprot id: W0I1T7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

582419:TES1 RS10095
gene id: 582419:TES1_RS10095
uniprot id: W0I5B2
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS07775
gene id: 582419:TES1_RS07775
uniprot id: W0I484
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS00225
gene id: 582419:TES1_RS00225
uniprot id: W0I0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

582419:TES1 RS06190
gene id: 582419:TES1_RS06190
uniprot id: W0I7X9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

582419:TES1 RS09545
gene id: 582419:TES1_RS09545
uniprot id: W0I556
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS00910
gene id: 582419:TES1_RS00910
uniprot id: W0I561
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

582419:TES1 RS03720
gene id: 582419:TES1_RS03720
uniprot id: W0I261
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

582419:TES1 RS01715
gene id: 582419:TES1_RS01715
uniprot id: W0I137
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

582419:TES1 RS01220
gene id: 582419:TES1_RS01220
uniprot id: W0I5G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

582419:TES1 RS09220
gene id: 582419:TES1_RS09220
uniprot id: W0I4U6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

582419:TES1 RS07750
gene id: 582419:TES1_RS07750
uniprot id: W0I481
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02575
gene id: 582419:TES1_RS02575
uniprot id: W0I575
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS08910
gene id: 582419:TES1_RS08910
uniprot id: W0I8L6
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS07760
gene id: 582419:TES1_RS07760
uniprot id: W0I443
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS03505
gene id: 582419:TES1_RS03505
uniprot id: W0I6P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

582419:TES1 RS01210
gene id: 582419:TES1_RS01210
uniprot id: W0I0Q6
names: Similarity
messages: Belongs to the MEMO1 family.

582419:TES1 RS01450
gene id: 582419:TES1_RS01450
uniprot id: W0I5K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

582419:TES1 RS01185
gene id: 582419:TES1_RS01185
uniprot id: W0I4G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

582419:TES1 RS06045
gene id: 582419:TES1_RS06045
uniprot id: W0I7Z5
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

582419:TES1 RS03120
gene id: 582419:TES1_RS03120
uniprot id: W0I6D6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

582419:TES1 RS09845
gene id: 582419:TES1_RS09845
uniprot id: W0IA03
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

582419:TES1 RS06975
gene id: 582419:TES1_RS06975
uniprot id: W0I8B9
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

582419:TES1 RS08915
gene id: 582419:TES1_RS08915
uniprot id: W0I9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

582419:TES1 RS00345
gene id: 582419:TES1_RS00345
uniprot id: W0I436
names: Similarity
messages: Belongs to the band 7/mec-2 family.

582419:TES1 RS00675
gene id: 582419:TES1_RS00675
uniprot id: W0I0F7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

582419:TES1 RS09010
gene id: 582419:TES1_RS09010
uniprot id: W0I4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

582419:TES1 RS00100
gene id: 582419:TES1_RS00100
uniprot id: W0I4S3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

582419:TES1 RS07705
gene id: 582419:TES1_RS07705
uniprot id: W0I8Q4
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS09725
gene id: 582419:TES1_RS09725
uniprot id: W0I593
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

582419:TES1 RS04300
gene id: 582419:TES1_RS04300
uniprot id: W0I720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS06035
gene id: 582419:TES1_RS06035
uniprot id: W0I395
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

582419:TES1 RS01645
gene id: 582419:TES1_RS01645
uniprot id: W0I5J5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

582419:TES1 RS01445
gene id: 582419:TES1_RS01445
uniprot id: W0I4K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

582419:TES1 RS01150
gene id: 582419:TES1_RS01150
uniprot id: W0I0P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

582419:TES1 RS09885
gene id: 582419:TES1_RS09885
uniprot id: W0I573
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS05860
gene id: 582419:TES1_RS05860
uniprot id: W0I7W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

582419:TES1 RS02505
gene id: 582419:TES1_RS02505
uniprot id: W0I648
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

582419:TES1 RS07710
gene id: 582419:TES1_RS07710
uniprot id: W0I433
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS10300
gene id: 582419:TES1_RS10300
uniprot id: W0I5E4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS01205
gene id: 582419:TES1_RS01205
uniprot id: W0I5B7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

582419:TES1 RS00835
gene id: 582419:TES1_RS00835
uniprot id: W0I548
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

582419:TES1 RS08705
gene id: 582419:TES1_RS08705
uniprot id: W0I8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS09125
gene id: 582419:TES1_RS09125
uniprot id: W0I8P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

582419:TES1 RS06395
gene id: 582419:TES1_RS06395
uniprot id: W0I3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

582419:TES1 RS03675
gene id: 582419:TES1_RS03675
uniprot id: W0I6M5
names: Similarity
messages: Belongs to the UPF0047 family.

582419:TES1 RS09160
gene id: 582419:TES1_RS09160
uniprot id: W0I4Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 2 family.
messages: Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

582419:TES1 RS05815
gene id: 582419:TES1_RS05815
uniprot id: W0I7R5
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

582419:TES1 RS02805
gene id: 582419:TES1_RS02805
uniprot id: W0I1R5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

582419:TES1 RS02625
gene id: 582419:TES1_RS02625
uniprot id: W0I585
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.

582419:TES1 RS08820
gene id: 582419:TES1_RS08820
uniprot id: W0I9C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

582419:TES1 RS09890
gene id: 582419:TES1_RS09890
uniprot id: W0I930
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

582419:TES1 RS09330
gene id: 582419:TES1_RS09330
uniprot id: W0I9Q5
names: Similarity
messages: Belongs to the carbamate kinase family.

582419:TES1 RS04070
gene id: 582419:TES1_RS04070
uniprot id: W0I2C4
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

582419:TES1 RS03040
gene id: 582419:TES1_RS03040
uniprot id: W0I6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

582419:TES1 RS10290
gene id: 582419:TES1_RS10290
uniprot id: W0I5J2
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

582419:TES1 RS00110
gene id: 582419:TES1_RS00110
uniprot id: W0I3Z6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

582419:TES1 RS06135
gene id: 582419:TES1_RS06135
uniprot id: W0I7W7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

582419:TES1 RS09990
gene id: 582419:TES1_RS09990
uniprot id: W0I594
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

582419:TES1 RS06165
gene id: 582419:TES1_RS06165
uniprot id: W0I7X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

582419:TES1 RS02935
gene id: 582419:TES1_RS02935
uniprot id: W0I1T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

582419:TES1 RS01155
gene id: 582419:TES1_RS01155
uniprot id: W0I4F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS03865
gene id: 582419:TES1_RS03865
uniprot id: W0I259
names: Similarity
messages: Belongs to the pyruvate kinase family.

582419:TES1 RS06090
gene id: 582419:TES1_RS06090
uniprot id: W0I745
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

582419:TES1 RS08720
gene id: 582419:TES1_RS08720
uniprot id: W0I9A3
names: Similarity
messages: Belongs to the UPF0146 family.

582419:TES1 RS07915
gene id: 582419:TES1_RS07915
uniprot id: W0I8U2
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02045
gene id: 582419:TES1_RS02045
uniprot id: W0I198
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS01340
gene id: 582419:TES1_RS01340
uniprot id: W0I0T3
names: Function
messages: Probably involved in the biogenesis of the ribosome.

582419:TES1 RS10000
gene id: 582419:TES1_RS10000
uniprot id: W0IA28
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

582419:TES1 RS10090
gene id: 582419:TES1_RS10090
uniprot id: W0IA01
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS09580
gene id: 582419:TES1_RS09580
uniprot id: W0I9Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

582419:TES1 RS09320
gene id: 582419:TES1_RS09320
uniprot id: W0I4W3
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

582419:TES1 RS03065
gene id: 582419:TES1_RS03065
uniprot id: W0I6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

582419:TES1 RS03730
gene id: 582419:TES1_RS03730
uniprot id: W0I233
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

582419:TES1 RS04320
gene id: 582419:TES1_RS04320
uniprot id: W0I640
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

582419:TES1 RS08800
gene id: 582419:TES1_RS08800
uniprot id: W0I4N5
names: Similarity
messages: Belongs to the UPF0216 family.

582419:TES1 RS05375
gene id: 582419:TES1_RS05375
uniprot id: W0I2X5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS10060
gene id: 582419:TES1_RS10060
uniprot id: W0I5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS07640
gene id: 582419:TES1_RS07640
uniprot id: W0I7V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS02985
gene id: 582419:TES1_RS02985
uniprot id: W0I1U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Membrane

582419:TES1 RS04585
gene id: 582419:TES1_RS04585
uniprot id: W0I767
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS05855
gene id: 582419:TES1_RS05855
uniprot id: W0I709
names: Similarity
messages: Belongs to the UPF0179 family.

582419:TES1 RS03435
gene id: 582419:TES1_RS03435
uniprot id: W0I211
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

582419:TES1 RS04765
gene id: 582419:TES1_RS04765
uniprot id: W0I2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

582419:TES1 RS02380
gene id: 582419:TES1_RS02380
uniprot id: W0I624
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

582419:TES1 RS08170
gene id: 582419:TES1_RS08170
uniprot id: W0I4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

582419:TES1 RS09540
gene id: 582419:TES1_RS09540
uniprot id: W0I9U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS03045
gene id: 582419:TES1_RS03045
uniprot id: W0I1S3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

582419:TES1 RS02105
gene id: 582419:TES1_RS02105
uniprot id: W0I174
names: Similarity
messages: Belongs to the peptidase U62 family.

582419:TES1 RS01030
gene id: 582419:TES1_RS01030
uniprot id: W0I0R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

582419:TES1 RS05105
gene id: 582419:TES1_RS05105
uniprot id: W0I6J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

582419:TES1 RS05475
gene id: 582419:TES1_RS05475
uniprot id: W0I315
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

582419:TES1 RS07380
gene id: 582419:TES1_RS07380
uniprot id: W0I7Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

582419:TES1 RS10230
gene id: 582419:TES1_RS10230
uniprot id: W0I993
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

582419:TES1 RS00995
gene id: 582419:TES1_RS00995
uniprot id: W0I4D4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

582419:TES1 RS02305
gene id: 582419:TES1_RS02305
uniprot id: W0I609
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

582419:TES1 RS05270
gene id: 582419:TES1_RS05270
uniprot id: W0I2Z0
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS06070
gene id: 582419:TES1_RS06070
uniprot id: W0I800
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

582419:TES1 RS02515
gene id: 582419:TES1_RS02515
uniprot id: W0I601
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

582419:TES1 RS01010
gene id: 582419:TES1_RS01010
uniprot id: W0I582
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

582419:TES1 RS06055
gene id: 582419:TES1_RS06055
uniprot id: W0I7V5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

582419:TES1 RS02435
gene id: 582419:TES1_RS02435
uniprot id: W0I1H6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

582419:TES1 RS02150
gene id: 582419:TES1_RS02150
uniprot id: W0I184
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

582419:TES1 RS06200
gene id: 582419:TES1_RS06200
uniprot id: W0I761
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

582419:TES1 RS07040
gene id: 582419:TES1_RS07040
uniprot id: W0I7J4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

582419:TES1 RS00280
gene id: 582419:TES1_RS00280
uniprot id: W0I4V3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

582419:TES1 RS02295
gene id: 582419:TES1_RS02295
uniprot id: W0I1B6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

582419:TES1 RS03285
gene id: 582419:TES1_RS03285
uniprot id: W0I6L4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

582419:TES1 RS08895
gene id: 582419:TES1_RS08895
uniprot id: W0I4U0
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

582419:TES1 RS02530
gene id: 582419:TES1_RS02530
uniprot id: W0I654
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

582419:TES1 RS08925
gene id: 582419:TES1_RS08925
uniprot id: W0I9E2
names: Function
messages: Part of a potassium transport system.

582419:TES1 RS05010
gene id: 582419:TES1_RS05010
uniprot id: W0I7D1
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS01215
gene id: 582419:TES1_RS01215
uniprot id: W0I4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

582419:TES1 RS07370
gene id: 582419:TES1_RS07370
uniprot id: W0I8J2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

582419:TES1 RS00250
gene id: 582419:TES1_RS00250
uniprot id: W0I0D5
names: Similarity
messages: Belongs to the threonine synthase family.

582419:TES1 RS04310
gene id: 582419:TES1_RS04310
uniprot id: W0I6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS01310
gene id: 582419:TES1_RS01310
uniprot id: W0I5D1
names: Similarity
messages: Belongs to the SDO1/SBDS family.

582419:TES1 RS02390
gene id: 582419:TES1_RS02390
uniprot id: W0I5X5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

582419:TES1 RS02835
gene id: 582419:TES1_RS02835
uniprot id: W0I1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

582419:TES1 RS01120
gene id: 582419:TES1_RS01120
uniprot id: W0I4F3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

582419:TES1 RS04945
gene id: 582419:TES1_RS04945
uniprot id: W0I787
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

582419:TES1 RS00525
gene id: 582419:TES1_RS00525
uniprot id: W0I465
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS04790
gene id: 582419:TES1_RS04790
uniprot id: W0I2Q0
names: Similarity
messages: Belongs to the peptidase S49 family.

582419:TES1 RS06655
gene id: 582419:TES1_RS06655
uniprot id: W0I8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

582419:TES1 RS09770
gene id: 582419:TES1_RS09770
uniprot id: W0I9Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

582419:TES1 RS02525
gene id: 582419:TES1_RS02525
uniprot id: W0I564
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582419:TES1 RS01080
gene id: 582419:TES1_RS01080
uniprot id: W0I0S8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

582419:TES1 RS09085
gene id: 582419:TES1_RS09085
uniprot id: W0I9G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

582419:TES1 RS07920
gene id: 582419:TES1_RS07920
uniprot id: W0I472
names: Similarity
messages: Belongs to the UPF0200 family.

582419:TES1 RS07155
gene id: 582419:TES1_RS07155
uniprot id: W0I8J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

582419:TES1 RS01500
gene id: 582419:TES1_RS01500
uniprot id: W0I4L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

582419:TES1 RS02040
gene id: 582419:TES1_RS02040
uniprot id: W0I5V1
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

582419:TES1 RS03485
gene id: 582419:TES1_RS03485
uniprot id: W0I218
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

582419:TES1 RS10010
gene id: 582419:TES1_RS10010
uniprot id: W0I5E2
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04380
gene id: 582419:TES1_RS04380
uniprot id: W0I2H2
names: Similarity
messages: Belongs to the UPF0252 family.

582419:TES1 RS09495
gene id: 582419:TES1_RS09495
uniprot id: W0I9P0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

582419:TES1 RS10255
gene id: 582419:TES1_RS10255
uniprot id: W0I998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

582419:TES1 RS00845
gene id: 582419:TES1_RS00845
uniprot id: W0I4B3
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

582419:TES1 RS02630
gene id: 582419:TES1_RS02630
uniprot id: W0I673
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS06830
gene id: 582419:TES1_RS06830
uniprot id: W0I8D6
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS07165
gene id: 582419:TES1_RS07165
uniprot id: W0I8F2
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

582419:TES1 RS01510
gene id: 582419:TES1_RS01510
uniprot id: W0I102
names: Similarity
messages: Belongs to the phosphohexose mutase family.

582419:TES1 RS04315
gene id: 582419:TES1_RS04315
uniprot id: W0I2D5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

582419:TES1 RS08425
gene id: 582419:TES1_RS08425
uniprot id: W0I4L1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

582419:TES1 RS08060
gene id: 582419:TES1_RS08060
uniprot id: W0I917
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

582419:TES1 RS04045
gene id: 582419:TES1_RS04045
uniprot id: W0I6T4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS01045
gene id: 582419:TES1_RS01045
uniprot id: W0I4E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

582419:TES1 RS10405
gene id: 582419:TES1_RS10405
uniprot id: W0IA97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

582419:TES1 RS03560
gene id: 582419:TES1_RS03560
uniprot id: W0I232
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

582419:TES1 RS07070
gene id: 582419:TES1_RS07070
uniprot id: W0I7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

582419:TES1 RS10600
gene id: 582419:TES1_RS10600
uniprot id: W0IA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

582419:TES1 RS04805
gene id: 582419:TES1_RS04805
uniprot id: W0I6B8
names: Similarity
messages: Belongs to the HypE family.

582419:TES1 RS08495
gene id: 582419:TES1_RS08495
uniprot id: W0I8E2
names: Subunit
messages: Homotetramer.

582419:TES1 RS06180
gene id: 582419:TES1_RS06180
uniprot id: W0I819
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

582419:TES1 RS07900
gene id: 582419:TES1_RS07900
uniprot id: W0I811
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02670
gene id: 582419:TES1_RS02670
uniprot id: W0I1J4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

582419:TES1 RS05295
gene id: 582419:TES1_RS05295
uniprot id: W0I2Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

582419:TES1 RS00990
gene id: 582419:TES1_RS00990
uniprot id: W0I0L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

582419:TES1 RS02970
gene id: 582419:TES1_RS02970
uniprot id: W0I1R0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

582419:TES1 RS01630
gene id: 582419:TES1_RS01630
uniprot id: W0I4N9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS10455
gene id: 582419:TES1_RS10455
uniprot id: W0I5M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

582419:TES1 RS04145
gene id: 582419:TES1_RS04145
uniprot id: W0I2D7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

582419:TES1 RS08840
gene id: 582419:TES1_RS08840
uniprot id: W0I4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

582419:TES1 RS02510
gene id: 582419:TES1_RS02510
uniprot id: W0I1J0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS06230
gene id: 582419:TES1_RS06230
uniprot id: W0I765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS06675
gene id: 582419:TES1_RS06675
uniprot id: W0I7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

582419:TES1 RS09445
gene id: 582419:TES1_RS09445
uniprot id: W0I4Y7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

582419:TES1 RS05030
gene id: 582419:TES1_RS05030
uniprot id: W0I6H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

582419:TES1 RS05695
gene id: 582419:TES1_RS05695
uniprot id: W0I6Y3
names: Similarity
messages: Belongs to the UPF0251 family.

582419:TES1 RS00375
gene id: 582419:TES1_RS00375
uniprot id: W0I525
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

582419:TES1 RS03410
gene id: 582419:TES1_RS03410
uniprot id: W0I205
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

582419:TES1 RS05635
gene id: 582419:TES1_RS05635
uniprot id: W0I6X4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

582419:TES1 RS09525
gene id: 582419:TES1_RS09525
uniprot id: W0I9P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

582419:TES1 RS10505
gene id: 582419:TES1_RS10505
uniprot id: W0I9F4
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

582419:TES1 RS05470
gene id: 582419:TES1_RS05470
uniprot id: W0I7K5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

582419:TES1 RS07245
gene id: 582419:TES1_RS07245
uniprot id: W0I3V3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

582419:TES1 RS02375
gene id: 582419:TES1_RS02375
uniprot id: W0I528
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

582419:TES1 RS03545
gene id: 582419:TES1_RS03545
uniprot id: W0I1Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

582419:TES1 RS05400
gene id: 582419:TES1_RS05400
uniprot id: W0I2Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582419:TES1 RS07995
gene id: 582419:TES1_RS07995
uniprot id: W0I8V9
names: Similarity
messages: Belongs to the UPF0215 family.

582419:TES1 RS07865
gene id: 582419:TES1_RS07865
uniprot id: W0I807
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

582419:TES1 RS08985
gene id: 582419:TES1_RS08985
uniprot id: W0I8M7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

582419:TES1 RS00230
gene id: 582419:TES1_RS00230
uniprot id: W0I4U7
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

582419:TES1 RS04855
gene id: 582419:TES1_RS04855
uniprot id: W0I2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

582419:TES1 RS08885
gene id: 582419:TES1_RS08885
uniprot id: W0I8L2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

582419:TES1 RS03585
gene id: 582419:TES1_RS03585
uniprot id: W0I238
names: Similarity
messages: Belongs to the UPF0128 family.

582419:TES1 RS03160
gene id: 582419:TES1_RS03160
uniprot id: W0I6I9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

582419:TES1 RS07085
gene id: 582419:TES1_RS07085
uniprot id: W0I3V9
names: Similarity
messages: Belongs to the AOR/FOR family.

582419:TES1 RS01195
gene id: 582419:TES1_RS01195
uniprot id: W0I5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

582419:TES1 RS03305
gene id: 582419:TES1_RS03305
uniprot id: W0I5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

582419:TES1 RS06575
gene id: 582419:TES1_RS06575
uniprot id: W0I7B4
names: Similarity
messages: Belongs to the UPF0252 family.

582419:TES1 RS06540
gene id: 582419:TES1_RS06540
uniprot id: W0I7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

582419:TES1 RS03930
gene id: 582419:TES1_RS03930
uniprot id: W0I2A1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

582419:TES1 RS05935
gene id: 582419:TES1_RS05935
uniprot id: W0I721
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

582419:TES1 RS10675
gene id: 582419:TES1_RS10675
uniprot id: W0IA03
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

582419:TES1 RS00885
gene id: 582419:TES1_RS00885
uniprot id: W0I558
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

582419:TES1 RS03295
gene id: 582419:TES1_RS03295
uniprot id: W0I6G7
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

582419:TES1 RS05900
gene id: 582419:TES1_RS05900
uniprot id: W0I7S8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

582419:TES1 RS03420
gene id: 582419:TES1_RS03420
uniprot id: W0I1X4
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

582419:TES1 RS00790
gene id: 582419:TES1_RS00790
uniprot id: W0I0H2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

582419:TES1 RS03600
gene id: 582419:TES1_RS03600
uniprot id: W0I5S3
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS02600
gene id: 582419:TES1_RS02600
uniprot id: W0I580
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

582419:TES1 RS01945
gene id: 582419:TES1_RS01945
uniprot id: W0I177
names: Similarity
messages: Belongs to the UPF0235 family.

582419:TES1 RS04530
gene id: 582419:TES1_RS04530
uniprot id: W0I671
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

582419:TES1 RS08780
gene id: 582419:TES1_RS08780
uniprot id: W0I8J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

582419:TES1 RS09390
gene id: 582419:TES1_RS09390
uniprot id: W0I9M2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

582419:TES1 RS06970
gene id: 582419:TES1_RS06970
uniprot id: W0I3U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

582419:TES1 RS02460
gene id: 582419:TES1_RS02460
uniprot id: W0I1I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

582419:TES1 RS07190
gene id: 582419:TES1_RS07190
uniprot id: W0I8F7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS02145
gene id: 582419:TES1_RS02145
uniprot id: W0I1B7
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

582419:TES1 RS06325
gene id: 582419:TES1_RS06325
uniprot id: W0I803
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

582419:TES1 RS02005
gene id: 582419:TES1_RS02005
uniprot id: W0I153
names: Similarity
messages: Belongs to the HypE family.

582419:TES1 RS01910
gene id: 582419:TES1_RS01910
uniprot id: W0I4S7
names: Subcellular Location Annotation
messages: Membrane

582419:TES1 RS04450
gene id: 582419:TES1_RS04450
uniprot id: W0I660
names: Similarity
messages: Belongs to the glutaredoxin family.

582419:TES1 RS09515
gene id: 582419:TES1_RS09515
uniprot id: W0I9T8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

582419:TES1 RS07100
gene id: 582419:TES1_RS07100
uniprot id: W0I7K2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

582419:TES1 RS09245
gene id: 582419:TES1_RS09245
uniprot id: W0I4V1
names: Similarity
messages: Belongs to the UPF0111 family.

582419:TES1 RS01345
gene id: 582419:TES1_RS01345
uniprot id: W0I4J0
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

582419:TES1 RS05145
gene id: 582419:TES1_RS05145
uniprot id: W0I2W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582419:TES1 RS00980
gene id: 582419:TES1_RS00980
uniprot id: W0I0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

582419:TES1 RS02640
gene id: 582419:TES1_RS02640
uniprot id: W0I629
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Binds 2 divalent metal cations per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

582419:TES1 RS01335
gene id: 582419:TES1_RS01335
uniprot id: W0I5D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

582419:TES1 RS08000
gene id: 582419:TES1_RS08000
uniprot id: W0I487
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

582419:TES1 RS02650
gene id: 582419:TES1_RS02650
uniprot id: W0I591
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

582419:TES1 RS01295
gene id: 582419:TES1_RS01295
uniprot id: W0I4H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

582419:TES1 RS01660
gene id: 582419:TES1_RS01660
uniprot id: W0I5P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

582419:TES1 RS01000
gene id: 582419:TES1_RS01000
uniprot id: W0I5C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

582419:TES1 RS07260
gene id: 582419:TES1_RS07260
uniprot id: W0I3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

582419:TES1 RS05435
gene id: 582419:TES1_RS05435
uniprot id: W0I7L9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

582419:TES1 RS08110
gene id: 582419:TES1_RS08110
uniprot id: W0I939
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

582419:TES1 RS09225
gene id: 582419:TES1_RS09225
uniprot id: W0I8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

582419:TES1 RS09380
gene id: 582419:TES1_RS09380
uniprot id: W0I9R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.