580340:TLIE RS07325
gene id: 580340:TLIE_RS07325
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS08120
gene id: 580340:TLIE_RS08120
uniprot id: G7V7N5
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS01585
gene id: 580340:TLIE_RS01585
uniprot id: G7V6U4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

580340:TLIE RS06265
gene id: 580340:TLIE_RS06265
uniprot id: G7V5N0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

580340:TLIE RS06845
gene id: 580340:TLIE_RS06845
uniprot id: G7V664
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

580340:TLIE RS07230
gene id: 580340:TLIE_RS07230
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS02445
gene id: 580340:TLIE_RS02445
uniprot id: G7V7X6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

580340:TLIE RS02485
gene id: 580340:TLIE_RS02485
uniprot id: G7V7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580340:TLIE RS02455
gene id: 580340:TLIE_RS02455
uniprot id: G7V7X8
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05955
gene id: 580340:TLIE_RS05955
uniprot id: G7V599
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS00075
gene id: 580340:TLIE_RS00075
uniprot id: G7V560
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS07780
gene id: 580340:TLIE_RS07780
uniprot id: G7V7A9
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06250
gene id: 580340:TLIE_RS06250
uniprot id: G7V5M7
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS01710
gene id: 580340:TLIE_RS01710
uniprot id: G7V745
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

580340:TLIE RS09835
gene id: 580340:TLIE_RS09835
uniprot id: G7VAH1
names: Similarity
messages: Belongs to the AOR/FOR family.

580340:TLIE RS09245
gene id: 580340:TLIE_RS09245
uniprot id: G7V8Y1
names: Similarity
messages: Belongs to the AOR/FOR family.

580340:TLIE RS05485
gene id: 580340:TLIE_RS05485
uniprot id: G7VAA0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

580340:TLIE RS02880
gene id: 580340:TLIE_RS02880
uniprot id: G7V8D3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

580340:TLIE RS00950
gene id: 580340:TLIE_RS00950
uniprot id: G7V6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

580340:TLIE RS05920
gene id: 580340:TLIE_RS05920
uniprot id: G7V592
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

580340:TLIE RS00525
gene id: 580340:TLIE_RS00525
uniprot id: G7V5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

580340:TLIE RS04450
gene id: 580340:TLIE_RS04450
uniprot id: G7V9P8
names: Similarity
messages: Belongs to the asp23 family.

580340:TLIE RS06980
gene id: 580340:TLIE_RS06980
uniprot id: G7V6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

580340:TLIE RS03045
gene id: 580340:TLIE_RS03045
uniprot id: G7V8G5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS02165
gene id: 580340:TLIE_RS02165
uniprot id: G7V7K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

580340:TLIE RS03290
gene id: 580340:TLIE_RS03290
uniprot id: G7V8T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

580340:TLIE RS02115
gene id: 580340:TLIE_RS02115
uniprot id: G7V7J4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

580340:TLIE RS06755
gene id: 580340:TLIE_RS06755
uniprot id: G7V646
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS05745
gene id: 580340:TLIE_RS05745
uniprot id: G7VAE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS02010
gene id: 580340:TLIE_RS02010
uniprot id: G7V7H6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

580340:TLIE RS03935
gene id: 580340:TLIE_RS03935
uniprot id: G7V9F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

580340:TLIE RS09210
gene id: 580340:TLIE_RS09210
uniprot id: G7V8X4
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06865
gene id: 580340:TLIE_RS06865
uniprot id: G7V668
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

580340:TLIE RS00385
gene id: 580340:TLIE_RS00385
uniprot id: G7V5J4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

580340:TLIE RS02125
gene id: 580340:TLIE_RS02125
uniprot id: G7V7J6
names: Similarity
messages: Belongs to the threonine aldolase family.

580340:TLIE RS04175
gene id: 580340:TLIE_RS04175
uniprot id: G7V9J7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

580340:TLIE RS05325
gene id: 580340:TLIE_RS05325
uniprot id: G7VA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

580340:TLIE RS05885
gene id: 580340:TLIE_RS05885
uniprot id: G7V586
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

580340:TLIE RS00470
gene id: 580340:TLIE_RS00470
uniprot id: G7V5T2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

580340:TLIE RS06115
gene id: 580340:TLIE_RS06115
uniprot id: G7V5D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

580340:TLIE RS03345
gene id: 580340:TLIE_RS03345
uniprot id: G7V8U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

580340:TLIE RS03030
gene id: 580340:TLIE_RS03030
uniprot id: G7V8G2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

580340:TLIE RS05560
gene id: 580340:TLIE_RS05560
uniprot id: G7VAA6
names: Similarity
messages: Belongs to the peptidase S16 family.

580340:TLIE RS08940
gene id: 580340:TLIE_RS08940
uniprot id: G7V8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS08905
gene id: 580340:TLIE_RS08905
uniprot id: G7V8I7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

580340:TLIE RS06770
gene id: 580340:TLIE_RS06770
uniprot id: G7V649
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

580340:TLIE RS03105
gene id: 580340:TLIE_RS03105
uniprot id: G7V8P9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

580340:TLIE RS09880
gene id: 580340:TLIE_RS09880
uniprot id: G7V6Q1
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05625
gene id: 580340:TLIE_RS05625
uniprot id: G7VAB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

580340:TLIE RS05420
gene id: 580340:TLIE_RS05420
uniprot id: G7VA87
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

580340:TLIE RS05295
gene id: 580340:TLIE_RS05295
uniprot id: G7VA61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

580340:TLIE RS04255
gene id: 580340:TLIE_RS04255
uniprot id: G7V9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

580340:TLIE RS03235
gene id: 580340:TLIE_RS03235
uniprot id: G7V8S5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

580340:TLIE RS02585
gene id: 580340:TLIE_RS02585
uniprot id: G7V804
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

580340:TLIE RS05310
gene id: 580340:TLIE_RS05310
uniprot id: G7VA64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

580340:TLIE RS03850
gene id: 580340:TLIE_RS03850
uniprot id: G7V9D6
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS09975
gene id: 580340:TLIE_RS09975
uniprot id: G7V9H9
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

580340:TLIE RS09795
gene id: 580340:TLIE_RS09795
uniprot id: G7VAG4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

580340:TLIE RS03530
gene id: 580340:TLIE_RS03530
uniprot id: G7V956
names: Similarity
messages: Belongs to the Skp family.

580340:TLIE RS06750
gene id: 580340:TLIE_RS06750
uniprot id: G7V645
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

580340:TLIE RS08455
gene id: 580340:TLIE_RS08455
uniprot id: G7V7V5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580340:TLIE RS06220
gene id: 580340:TLIE_RS06220
uniprot id: G7V5M1
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00065
gene id: 580340:TLIE_RS00065
uniprot id: G7V558
names: Similarity
messages: Belongs to the AOR/FOR family.

580340:TLIE RS01370
gene id: 580340:TLIE_RS01370
uniprot id: G7V6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS05815
gene id: 580340:TLIE_RS05815
uniprot id: G7V573
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

580340:TLIE RS04205
gene id: 580340:TLIE_RS04205
uniprot id: G7V9K3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

580340:TLIE RS07605
gene id: 580340:TLIE_RS07605
uniprot id: G7V703
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

580340:TLIE RS05860
gene id: 580340:TLIE_RS05860
uniprot id: G7V582
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS07980
gene id: 580340:TLIE_RS07980
uniprot id: G7V7E5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

580340:TLIE RS05235
gene id: 580340:TLIE_RS05235
uniprot id: G7VA49
names: Similarity
messages: Belongs to the peptidase U62 family.

580340:TLIE RS00020
gene id: 580340:TLIE_RS00020
uniprot id: G7V549
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

580340:TLIE RS05670
gene id: 580340:TLIE_RS05670
uniprot id: G7VAC8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS05270
gene id: 580340:TLIE_RS05270
uniprot id: G7VA56
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

580340:TLIE RS04735
gene id: 580340:TLIE_RS04735
uniprot id: G7V9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

580340:TLIE RS09420
gene id: 580340:TLIE_RS09420
uniprot id: G7V908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

580340:TLIE RS03315
gene id: 580340:TLIE_RS03315
uniprot id: G7V8U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

580340:TLIE RS08870
gene id: 580340:TLIE_RS08870
uniprot id: G7V8I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

580340:TLIE RS02030
gene id: 580340:TLIE_RS02030
uniprot id: G7V7I0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

580340:TLIE RS02175
gene id: 580340:TLIE_RS02175
uniprot id: G7V7K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

580340:TLIE RS05190
gene id: 580340:TLIE_RS05190
uniprot id: G7VA40
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

580340:TLIE RS04310
gene id: 580340:TLIE_RS04310
uniprot id: G7V9M5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

580340:TLIE RS05700
gene id: 580340:TLIE_RS05700
uniprot id: G7VAD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

580340:TLIE RS01025
gene id: 580340:TLIE_RS01025
uniprot id: G7V6B7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

580340:TLIE RS05650
gene id: 580340:TLIE_RS05650
uniprot id: G7VAC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS07470
gene id: 580340:TLIE_RS07470
uniprot id: G7V6X8
names: Similarity
messages: Belongs to the UPF0173 family.

580340:TLIE RS04245
gene id: 580340:TLIE_RS04245
uniprot id: G7V9L2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

580340:TLIE RS01485
gene id: 580340:TLIE_RS01485
uniprot id: G7V6S4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

580340:TLIE RS04230
gene id: 580340:TLIE_RS04230
uniprot id: G7V9K9
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

580340:TLIE RS05495
gene id: 580340:TLIE_RS05495
uniprot id: G7VAA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

580340:TLIE RS03795
gene id: 580340:TLIE_RS03795
uniprot id: G7V9A6
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

580340:TLIE RS09855
gene id: 580340:TLIE_RS09855
uniprot id: G7V5T5
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

580340:TLIE RS08270
gene id: 580340:TLIE_RS08270
uniprot id: G7V7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

580340:TLIE RS00255
gene id: 580340:TLIE_RS00255
uniprot id: G7V5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

580340:TLIE RS09325
gene id: 580340:TLIE_RS09325
uniprot id: G7V8Z5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

580340:TLIE RS00320
gene id: 580340:TLIE_RS00320
uniprot id: G7V5I2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

580340:TLIE RS06745
gene id: 580340:TLIE_RS06745
uniprot id: G7V644
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

580340:TLIE RS01495
gene id: 580340:TLIE_RS01495
uniprot id: G7V6S6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

580340:TLIE RS03725
gene id: 580340:TLIE_RS03725
uniprot id: G7V993
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

580340:TLIE RS06830
gene id: 580340:TLIE_RS06830
uniprot id: G7V661
names: Similarity
messages: Belongs to the glutamine synthetase family.

580340:TLIE RS02430
gene id: 580340:TLIE_RS02430
uniprot id: G7V7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS02255
gene id: 580340:TLIE_RS02255
uniprot id: G7V7L8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

580340:TLIE RS09080
gene id: 580340:TLIE_RS09080
uniprot id: G7V8M3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

580340:TLIE RS05595
gene id: 580340:TLIE_RS05595
uniprot id: G7VAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

580340:TLIE RS07695
gene id: 580340:TLIE_RS07695
uniprot id: G7V719
names: Similarity
messages: Belongs to the UPF0166 family.

580340:TLIE RS05145
gene id: 580340:TLIE_RS05145
uniprot id: G7VA31
names: Similarity
messages: Belongs to the asparaginase 1 family.

580340:TLIE RS05380
gene id: 580340:TLIE_RS05380
uniprot id: G7VA79
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

580340:TLIE RS08770
gene id: 580340:TLIE_RS08770
uniprot id: G7V890
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS00580
gene id: 580340:TLIE_RS00580
uniprot id: G7V5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

580340:TLIE RS09435
gene id: 580340:TLIE_RS09435
uniprot id: G7V911
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

580340:TLIE RS01110
gene id: 580340:TLIE_RS01110
uniprot id: G7V6D5
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS08180
gene id: 580340:TLIE_RS08180
uniprot id: G7V7P6
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06620
gene id: 580340:TLIE_RS06620
uniprot id: G7V622
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

580340:TLIE RS04135
gene id: 580340:TLIE_RS04135
uniprot id: G7V9I9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580340:TLIE RS03440
gene id: 580340:TLIE_RS03440
uniprot id: G7V8W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

580340:TLIE RS02765
gene id: 580340:TLIE_RS02765
uniprot id: G7V8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

580340:TLIE RS05895
gene id: 580340:TLIE_RS05895
uniprot id: G7V588
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

580340:TLIE RS06395
gene id: 580340:TLIE_RS06395
uniprot id: G7V5Q4
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS03065
gene id: 580340:TLIE_RS03065
uniprot id: G7V8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

580340:TLIE RS03075
gene id: 580340:TLIE_RS03075
uniprot id: G7V8H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

580340:TLIE RS08345
gene id: 580340:TLIE_RS08345
uniprot id: G7V7T3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

580340:TLIE RS07985
gene id: 580340:TLIE_RS07985
uniprot id: G7V7E6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS08415
gene id: 580340:TLIE_RS08415
uniprot id: G7V7U7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

580340:TLIE RS05750
gene id: 580340:TLIE_RS05750
uniprot id: G7VAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

580340:TLIE RS06630
gene id: 580340:TLIE_RS06630
uniprot id: G7V624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

580340:TLIE RS07485
gene id: 580340:TLIE_RS07485
uniprot id: G7V6Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS00570
gene id: 580340:TLIE_RS00570
uniprot id: G7V5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

580340:TLIE RS02700
gene id: 580340:TLIE_RS02700
uniprot id: G7V826
names: Similarity
messages: Belongs to the UPF0102 family.

580340:TLIE RS07390
gene id: 580340:TLIE_RS07390
uniprot id: G7V6W2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

580340:TLIE RS02590
gene id: 580340:TLIE_RS02590
uniprot id: G7V805
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

580340:TLIE RS03945
gene id: 580340:TLIE_RS03945
uniprot id: G7V9F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

580340:TLIE RS05330
gene id: 580340:TLIE_RS05330
uniprot id: G7VA68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

580340:TLIE RS08360
gene id: 580340:TLIE_RS08360
uniprot id: G7V7T6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

580340:TLIE RS02395
gene id: 580340:TLIE_RS02395
uniprot id: G7V7W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

580340:TLIE RS04590
gene id: 580340:TLIE_RS04590
uniprot id: G7V9S5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

580340:TLIE RS08850
gene id: 580340:TLIE_RS08850
uniprot id: G7V8H6
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS07990
gene id: 580340:TLIE_RS07990
uniprot id: G7V7E7
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06925
gene id: 580340:TLIE_RS06925
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS01920
gene id: 580340:TLIE_RS01920
uniprot id: G7V786
names: Similarity
messages: Belongs to the UPF0047 family.

580340:TLIE RS01800
gene id: 580340:TLIE_RS01800
uniprot id: G7V762
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

580340:TLIE RS03695
gene id: 580340:TLIE_RS03695
uniprot id: G7V986
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

580340:TLIE RS01880
gene id: 580340:TLIE_RS01880
uniprot id: G7V778
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

580340:TLIE RS05425
gene id: 580340:TLIE_RS05425
uniprot id: G7VA88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS00760
gene id: 580340:TLIE_RS00760
uniprot id: G7V5Y9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

580340:TLIE RS08845
gene id: 580340:TLIE_RS08845
uniprot id: G7V8H5
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06690
gene id: 580340:TLIE_RS06690
uniprot id: G7V634
names: Similarity
messages: Belongs to the thioredoxin family.

580340:TLIE RS06090
gene id: 580340:TLIE_RS06090
uniprot id: G7V5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

580340:TLIE RS00515
gene id: 580340:TLIE_RS00515
uniprot id: G7V5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

580340:TLIE RS08485
gene id: 580340:TLIE_RS08485
uniprot id: G7V834
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS04810
gene id: 580340:TLIE_RS04810
uniprot id: G7V9W8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

580340:TLIE RS05925
gene id: 580340:TLIE_RS05925
uniprot id: G7V593
names: Similarity
messages: Belongs to the SAICAR synthetase family.

580340:TLIE RS02820
gene id: 580340:TLIE_RS02820
uniprot id: G7V8C1
names: Function
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

580340:TLIE RS02565
gene id: 580340:TLIE_RS02565
uniprot id: G7V800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

580340:TLIE RS04725
gene id: 580340:TLIE_RS04725
uniprot id: G7V9V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS03585
gene id: 580340:TLIE_RS03585
uniprot id: G7V967
names: Similarity
messages: Belongs to the band 7/mec-2 family.

580340:TLIE RS03355
gene id: 580340:TLIE_RS03355
uniprot id: G7V8U8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

580340:TLIE RS09690
gene id: 580340:TLIE_RS09690
uniprot id: G7V9D4
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

580340:TLIE RS05360
gene id: 580340:TLIE_RS05360
uniprot id: G7VA75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

580340:TLIE RS06045
gene id: 580340:TLIE_RS06045
uniprot id: G7V5B6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS06050
gene id: 580340:TLIE_RS06050
uniprot id: G7V5B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

580340:TLIE RS03990
gene id: 580340:TLIE_RS03990
uniprot id: G7V9G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

580340:TLIE RS07725
gene id: 580340:TLIE_RS07725
uniprot id: G7V798
names: Similarity
messages: Belongs to the universal stress protein A family.

580340:TLIE RS03575
gene id: 580340:TLIE_RS03575
uniprot id: G7V965
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

580340:TLIE RS09505
gene id: 580340:TLIE_RS09505
uniprot id: G7V924
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05865
gene id: 580340:TLIE_RS05865
uniprot id: G7V583
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

580340:TLIE RS02475
gene id: 580340:TLIE_RS02475
uniprot id: G7V7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580340:TLIE RS08970
gene id: 580340:TLIE_RS08970
uniprot id: G7V8K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580340:TLIE RS01700
gene id: 580340:TLIE_RS01700
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS03350
gene id: 580340:TLIE_RS03350
uniprot id: G7V8U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

580340:TLIE RS00405
gene id: 580340:TLIE_RS00405
uniprot id: G7V5J8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

580340:TLIE RS06810
gene id: 580340:TLIE_RS06810
uniprot id: G7V657
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

580340:TLIE RS04080
gene id: 580340:TLIE_RS04080
uniprot id: G7V9H8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

580340:TLIE RS03570
gene id: 580340:TLIE_RS03570
uniprot id: G7V964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

580340:TLIE RS01965
gene id: 580340:TLIE_RS01965
uniprot id: G7V795
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

580340:TLIE RS05395
gene id: 580340:TLIE_RS05395
uniprot id: G7VA82
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS06995
gene id: 580340:TLIE_RS06995
uniprot id: G7V6G6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

580340:TLIE RS09425
gene id: 580340:TLIE_RS09425
uniprot id: G7V909
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580340:TLIE RS08560
gene id: 580340:TLIE_RS08560
uniprot id: G7V849
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS05065
gene id: 580340:TLIE_RS05065
uniprot id: G7VA15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

580340:TLIE RS04640
gene id: 580340:TLIE_RS04640
uniprot id: G7V9T5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

580340:TLIE RS08570
gene id: 580340:TLIE_RS08570
uniprot id: G7V851
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS01910
gene id: 580340:TLIE_RS01910
uniprot id: G7V784
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS01095
gene id: 580340:TLIE_RS01095
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS07360
gene id: 580340:TLIE_RS07360
uniprot id: G7V6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS06330
gene id: 580340:TLIE_RS06330
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS01960
gene id: 580340:TLIE_RS01960
uniprot id: G7V794
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

580340:TLIE RS06485
gene id: 580340:TLIE_RS06485
uniprot id: G7V5S2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

580340:TLIE RS06915
gene id: 580340:TLIE_RS06915
uniprot id: G7V678
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS07250
gene id: 580340:TLIE_RS07250
uniprot id: G7V6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

580340:TLIE RS04500
gene id: 580340:TLIE_RS04500
uniprot id: G7V9Q8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

580340:TLIE RS08500
gene id: 580340:TLIE_RS08500
uniprot id: G7V837
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

580340:TLIE RS05760
gene id: 580340:TLIE_RS05760
uniprot id: G7V563
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04335
gene id: 580340:TLIE_RS04335
uniprot id: G7V9N0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

580340:TLIE RS02155
gene id: 580340:TLIE_RS02155
uniprot id: G7V7K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

580340:TLIE RS00380
gene id: 580340:TLIE_RS00380
uniprot id: G7V5J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

580340:TLIE RS01135
gene id: 580340:TLIE_RS01135
uniprot id: G7V6E0
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

580340:TLIE RS07150
gene id: 580340:TLIE_RS07150
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS01865
gene id: 580340:TLIE_RS01865
uniprot id: G7V775
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

580340:TLIE RS00710
gene id: 580340:TLIE_RS00710
uniprot id: G7V5Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580340:TLIE RS07410
gene id: 580340:TLIE_RS07410
uniprot id: G7V6W6
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS03110
gene id: 580340:TLIE_RS03110
uniprot id: G7V8Q0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

580340:TLIE RS07380
gene id: 580340:TLIE_RS07380
uniprot id: G7V6W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

580340:TLIE RS09640
gene id: 580340:TLIE_RS09640
uniprot id: G7V9C4
names: Similarity
messages: Belongs to the ParB family.

580340:TLIE RS01230
gene id: 580340:TLIE_RS01230
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS05445
gene id: 580340:TLIE_RS05445
uniprot id: G7VA92
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

580340:TLIE RS00755
gene id: 580340:TLIE_RS00755
uniprot id: G7V5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

580340:TLIE RS06640
gene id: 580340:TLIE_RS06640
uniprot id: G7V626
names: Similarity
messages: Belongs to the AlaDH/PNT family.

580340:TLIE RS06205
gene id: 580340:TLIE_RS06205
uniprot id: G7V5L8
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

580340:TLIE RS04460
gene id: 580340:TLIE_RS04460
uniprot id: G7V9Q0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

580340:TLIE RS00745
gene id: 580340:TLIE_RS00745
uniprot id: G7V5Y6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS09720
gene id: 580340:TLIE_RS09720
uniprot id: G7VAE9
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

580340:TLIE RS05200
gene id: 580340:TLIE_RS05200
uniprot id: G7VA42
names: Similarity
messages: Belongs to the TlyA family.

580340:TLIE RS02505
gene id: 580340:TLIE_RS02505
uniprot id: G7V7Y8
names: Similarity
messages: Belongs to the AOR/FOR family.

580340:TLIE RS07205
gene id: 580340:TLIE_RS07205
uniprot id: G7V6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

580340:TLIE RS06825
gene id: 580340:TLIE_RS06825
uniprot id: G7V660
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS06720
gene id: 580340:TLIE_RS06720
uniprot id: G7V639
names: Similarity
messages: Belongs to the HupF/HypC family.

580340:TLIE RS05655
gene id: 580340:TLIE_RS05655
uniprot id: G7VAC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

580340:TLIE RS02235
gene id: 580340:TLIE_RS02235
uniprot id: G7V7L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

580340:TLIE RS04885
gene id: 580340:TLIE_RS04885
uniprot id: G7V9Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

580340:TLIE RS01690
gene id: 580340:TLIE_RS01690
uniprot id: G7V742
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

580340:TLIE RS03750
gene id: 580340:TLIE_RS03750
uniprot id: G7V998
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

580340:TLIE RS00375
gene id: 580340:TLIE_RS00375
uniprot id: G7V5J2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

580340:TLIE RS00990
gene id: 580340:TLIE_RS00990
uniprot id: G7V6B0
names: Subcellular Location Annotation
messages: Bacterial microcompartment

580340:TLIE RS06600
gene id: 580340:TLIE_RS06600
uniprot id: G7V618
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

580340:TLIE RS09130
gene id: 580340:TLIE_RS09130
uniprot id: G7V8N3
names: Similarity
messages: Belongs to the universal stress protein A family.

580340:TLIE RS09170
gene id: 580340:TLIE_RS09170
uniprot id: G7V8P2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

580340:TLIE RS05875
gene id: 580340:TLIE_RS05875
uniprot id: G7V584
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

580340:TLIE RS09220
gene id: 580340:TLIE_RS09220
uniprot id: G7V8X6
names: Similarity
messages: Belongs to the TPP enzyme family.

580340:TLIE RS03260
gene id: 580340:TLIE_RS03260
uniprot id: G7V8T0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

580340:TLIE RS01205
gene id: 580340:TLIE_RS01205
uniprot id: G7V6E9
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

580340:TLIE RS06065
gene id: 580340:TLIE_RS06065
uniprot id: G7V5C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Belongs to the CutA family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

580340:TLIE RS09725
gene id: 580340:TLIE_RS09725
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS05210
gene id: 580340:TLIE_RS05210
uniprot id: G7VA44
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

580340:TLIE RS02240
gene id: 580340:TLIE_RS02240
uniprot id: G7V7L6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

580340:TLIE RS05135
gene id: 580340:TLIE_RS05135
uniprot id: G7VA29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

580340:TLIE RS05640
gene id: 580340:TLIE_RS05640
uniprot id: G7VAC2
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS02835
gene id: 580340:TLIE_RS02835
uniprot id: G7V8C4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

580340:TLIE RS05275
gene id: 580340:TLIE_RS05275
uniprot id: G7VA57
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

580340:TLIE RS03085
gene id: 580340:TLIE_RS03085
uniprot id: G7V8P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

580340:TLIE RS08045
gene id: 580340:TLIE_RS08045
uniprot id: G7V7F8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

580340:TLIE RS09430
gene id: 580340:TLIE_RS09430
uniprot id: G7V910
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580340:TLIE RS01560
gene id: 580340:TLIE_RS01560
uniprot id: G7V6T9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS04970
gene id: 580340:TLIE_RS04970
uniprot id: G7V9Z6
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

580340:TLIE RS03140
gene id: 580340:TLIE_RS03140
uniprot id: G7V8Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

580340:TLIE RS03305
gene id: 580340:TLIE_RS03305
uniprot id: G7V8T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

580340:TLIE RS06590
gene id: 580340:TLIE_RS06590
uniprot id: G7V616
names: Similarity
messages: Belongs to the peptidase M24B family.

580340:TLIE RS07090
gene id: 580340:TLIE_RS07090
uniprot id: G7V6I4
names: Similarity
messages: Belongs to the peptidase S41A family.

580340:TLIE RS02220
gene id: 580340:TLIE_RS02220
uniprot id: G7V7L4
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00395
gene id: 580340:TLIE_RS00395
uniprot id: G7V5J6
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS03160
gene id: 580340:TLIE_RS03160
uniprot id: G7V8R0
names: Similarity
messages: Belongs to the RecJ family.

580340:TLIE RS09315
gene id: 580340:TLIE_RS09315
uniprot id: G7V8Z3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

580340:TLIE RS05070
gene id: 580340:TLIE_RS05070
uniprot id: G7VA16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

580340:TLIE RS04475
gene id: 580340:TLIE_RS04475
uniprot id: G7V9Q3
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

580340:TLIE RS09865
gene id: 580340:TLIE_RS09865
uniprot id: G7V6B6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

580340:TLIE RS03385
gene id: 580340:TLIE_RS03385
uniprot id: G7V8V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

580340:TLIE RS07385
gene id: 580340:TLIE_RS07385
uniprot id: G7V6W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

580340:TLIE RS07755
gene id: 580340:TLIE_RS07755
uniprot id: G7V7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

580340:TLIE RS09495
gene id: 580340:TLIE_RS09495
uniprot id: G7V923
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

580340:TLIE RS05040
gene id: 580340:TLIE_RS05040
uniprot id: G7VA10
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05410
gene id: 580340:TLIE_RS05410
uniprot id: G7VA85
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

580340:TLIE RS04355
gene id: 580340:TLIE_RS04355
uniprot id: G7V9N4
names: Similarity
messages: Belongs to the CinA family.

580340:TLIE RS03415
gene id: 580340:TLIE_RS03415
uniprot id: G7V8W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

580340:TLIE RS07280
gene id: 580340:TLIE_RS07280
uniprot id: G7V6L7
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

580340:TLIE RS07915
gene id: 580340:TLIE_RS07915
uniprot id: G7V7D2
names: Similarity
messages: Belongs to the universal stress protein A family.

580340:TLIE RS01950
gene id: 580340:TLIE_RS01950
uniprot id: G7V792
names: Similarity
messages: Belongs to the peptidase C56 family.

580340:TLIE RS07760
gene id: 580340:TLIE_RS07760
uniprot id: G7V7A5
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

580340:TLIE RS04400
gene id: 580340:TLIE_RS04400
uniprot id: G7V9N8
names: Similarity
messages: Belongs to the GSP E family.

580340:TLIE RS03395
gene id: 580340:TLIE_RS03395
uniprot id: G7V8V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

580340:TLIE RS01890
gene id: 580340:TLIE_RS01890
uniprot id: G7V780
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

580340:TLIE RS02545
gene id: 580340:TLIE_RS02545
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS04250
gene id: 580340:TLIE_RS04250
uniprot id: G7V9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

580340:TLIE RS00275
gene id: 580340:TLIE_RS00275
uniprot id: G7V5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

580340:TLIE RS00575
gene id: 580340:TLIE_RS00575
uniprot id: G7V5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

580340:TLIE RS00765
gene id: 580340:TLIE_RS00765
uniprot id: G7V5Z0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

580340:TLIE RS03035
gene id: 580340:TLIE_RS03035
uniprot id: G7V8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

580340:TLIE RS00420
gene id: 580340:TLIE_RS00420
uniprot id: G7V5K1
names: Similarity
messages: Belongs to the MotB family.

580340:TLIE RS07180
gene id: 580340:TLIE_RS07180
uniprot id: G7V6J8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

580340:TLIE RS08100
gene id: 580340:TLIE_RS08100
uniprot id: G7V7N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580340:TLIE RS02720
gene id: 580340:TLIE_RS02720
uniprot id: G7V8A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

580340:TLIE RS09710
gene id: 580340:TLIE_RS09710
uniprot id: G7VAE7
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS05085
gene id: 580340:TLIE_RS05085
uniprot id: G7VA19
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

580340:TLIE RS06440
gene id: 580340:TLIE_RS06440
uniprot id: G7V5R3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

580340:TLIE RS04345
gene id: 580340:TLIE_RS04345
uniprot id: G7V9N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

580340:TLIE RS03275
gene id: 580340:TLIE_RS03275
uniprot id: G7V8T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

580340:TLIE RS06470
gene id: 580340:TLIE_RS06470
uniprot id: G7V5R9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

580340:TLIE RS08110
gene id: 580340:TLIE_RS08110
uniprot id: G7V7N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580340:TLIE RS00915
gene id: 580340:TLIE_RS00915
uniprot id: G7V696
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

580340:TLIE RS04700
gene id: 580340:TLIE_RS04700
uniprot id: G7V9U7
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

580340:TLIE RS03870
gene id: 580340:TLIE_RS03870
uniprot id: G7V9E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

580340:TLIE RS10095
gene id: 580340:TLIE_RS10095
uniprot id: G7V8N8
names: Similarity
messages: Belongs to the universal stress protein A family.

580340:TLIE RS04980
gene id: 580340:TLIE_RS04980
uniprot id: G7V9Z8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

580340:TLIE RS01760
gene id: 580340:TLIE_RS01760
uniprot id: G7V754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS02935
gene id: 580340:TLIE_RS02935
uniprot id: G7V8E4
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00155
gene id: 580340:TLIE_RS00155
uniprot id: G7V5E9
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05820
gene id: 580340:TLIE_RS05820
uniprot id: G7V574
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

580340:TLIE RS06210
gene id: 580340:TLIE_RS06210
uniprot id: G7V5L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580340:TLIE RS10065
gene id: 580340:TLIE_RS10065
uniprot id: G7V7U0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

580340:TLIE RS02150
gene id: 580340:TLIE_RS02150
uniprot id: G7V7K1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

580340:TLIE RS00465
gene id: 580340:TLIE_RS00465
uniprot id: G7V5T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

580340:TLIE RS06100
gene id: 580340:TLIE_RS06100
uniprot id: G7V5C8
names: Similarity
messages: Belongs to the carbamate kinase family.

580340:TLIE RS01755
gene id: 580340:TLIE_RS01755
uniprot id: G7V753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580340:TLIE RS07440
gene id: 580340:TLIE_RS07440
uniprot id: G7V6X2
names: Similarity
messages: Belongs to the DtxR/MntR family.

580340:TLIE RS09125
gene id: 580340:TLIE_RS09125
uniprot id: G7V8N2
names: Similarity
messages: Belongs to the universal stress protein A family.

580340:TLIE RS08105
gene id: 580340:TLIE_RS08105
uniprot id: G7V7N2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580340:TLIE RS03400
gene id: 580340:TLIE_RS03400
uniprot id: G7V8V7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

580340:TLIE RS02895
gene id: 580340:TLIE_RS02895
uniprot id: G7V8D6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

580340:TLIE RS07395
gene id: 580340:TLIE_RS07395
uniprot id: G7V6W3
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

580340:TLIE RS09105
gene id: 580340:TLIE_RS09105
uniprot id: G7V8M8
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS09385
gene id: 580340:TLIE_RS09385
uniprot id: G7V903
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

580340:TLIE RS08765
gene id: 580340:TLIE_RS08765
uniprot id: G7V889
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

580340:TLIE RS05705
gene id: 580340:TLIE_RS05705
uniprot id: G7VAD5
names: Similarity
messages: Belongs to the fabD family.

580340:TLIE RS06055
gene id: 580340:TLIE_RS06055
uniprot id: G7V5B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS00800
gene id: 580340:TLIE_RS00800
uniprot id: G7V5Z7
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05240
gene id: 580340:TLIE_RS05240
uniprot id: G7VA50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

580340:TLIE RS00200
gene id: 580340:TLIE_RS00200
uniprot id: G7V5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

580340:TLIE RS00725
gene id: 580340:TLIE_RS00725
uniprot id: G7V5Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04270
gene id: 580340:TLIE_RS04270
uniprot id: G7V9L7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

580340:TLIE RS05475
gene id: 580340:TLIE_RS05475
uniprot id: G7VA98
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

580340:TLIE RS02685
gene id: 580340:TLIE_RS02685
uniprot id: G7V823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

580340:TLIE RS03265
gene id: 580340:TLIE_RS03265
uniprot id: G7V8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

580340:TLIE RS00210
gene id: 580340:TLIE_RS00210
uniprot id: G7V5G0
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

580340:TLIE RS05965
gene id: 580340:TLIE_RS05965
uniprot id: G7V5A1
names: Similarity
messages: Belongs to the GARS family.

580340:TLIE RS06605
gene id: 580340:TLIE_RS06605
uniprot id: G7V619
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

580340:TLIE RS00605
gene id: 580340:TLIE_RS00605
uniprot id: G7V5V9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

580340:TLIE RS03715
gene id: 580340:TLIE_RS03715
uniprot id: G7V991
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS00095
gene id: 580340:TLIE_RS00095
uniprot id: G7V5D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS04675
gene id: 580340:TLIE_RS04675
uniprot id: G7V9U2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

580340:TLIE RS07710
gene id: 580340:TLIE_RS07710
uniprot id: G7V722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

580340:TLIE RS07210
gene id: 580340:TLIE_RS07210
uniprot id: G7V6K3
names: Similarity
messages: Belongs to the UPF0045 family.

580340:TLIE RS06255
gene id: 580340:TLIE_RS06255
uniprot id: G7V5M8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

580340:TLIE RS01385
gene id: 580340:TLIE_RS01385
uniprot id: G7V6Q5
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS01390
gene id: 580340:TLIE_RS01390
uniprot id: G7V6Q6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580340:TLIE RS05940
gene id: 580340:TLIE_RS05940
uniprot id: G7V596
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

580340:TLIE RS05315
gene id: 580340:TLIE_RS05315
uniprot id: G7VA65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

580340:TLIE RS05220
gene id: 580340:TLIE_RS05220
uniprot id: G7VA46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

580340:TLIE RS00700
gene id: 580340:TLIE_RS00700
uniprot id: G7V5X8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

580340:TLIE RS02840
gene id: 580340:TLIE_RS02840
uniprot id: G7V8C5
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS04760
gene id: 580340:TLIE_RS04760
uniprot id: G7V9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

580340:TLIE RS03770
gene id: 580340:TLIE_RS03770
uniprot id: G7V9A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

580340:TLIE RS05680
gene id: 580340:TLIE_RS05680
uniprot id: G7VAD0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

580340:TLIE RS05465
gene id: 580340:TLIE_RS05465
uniprot id: G7VA96
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

580340:TLIE RS02420
gene id: 580340:TLIE_RS02420
uniprot id: G7V7X1
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS04645
gene id: 580340:TLIE_RS04645
uniprot id: G7V9T6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS03730
gene id: 580340:TLIE_RS03730
uniprot id: G7V994
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

580340:TLIE RS01665
gene id: 580340:TLIE_RS01665
uniprot id: G7V737
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS01030
gene id: 580340:TLIE_RS01030
uniprot id: G7V6B8
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

580340:TLIE RS00540
gene id: 580340:TLIE_RS00540
uniprot id: G7V5U6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

580340:TLIE RS02850
gene id: 580340:TLIE_RS02850
uniprot id: G7V8C7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

580340:TLIE RS06835
gene id: 580340:TLIE_RS06835
uniprot id: G7V662
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00535
gene id: 580340:TLIE_RS00535
uniprot id: G7V5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

580340:TLIE RS06840
gene id: 580340:TLIE_RS06840
uniprot id: G7V663
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

580340:TLIE RS03375
gene id: 580340:TLIE_RS03375
uniprot id: G7V8V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

580340:TLIE RS03125
gene id: 580340:TLIE_RS03125
uniprot id: G7V8Q3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

580340:TLIE RS06895
gene id: 580340:TLIE_RS06895
uniprot id: G7V674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

580340:TLIE RS08665
gene id: 580340:TLIE_RS08665
uniprot id: G7V870
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS04000
gene id: 580340:TLIE_RS04000
uniprot id: G7V9G5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

580340:TLIE RS00240
gene id: 580340:TLIE_RS00240
uniprot id: G7V5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

580340:TLIE RS04985
gene id: 580340:TLIE_RS04985
uniprot id: G7V9Z9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

580340:TLIE RS06275
gene id: 580340:TLIE_RS06275
uniprot id: G7V5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS06020
gene id: 580340:TLIE_RS06020
uniprot id: G7V5B1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

580340:TLIE RS03215
gene id: 580340:TLIE_RS03215
uniprot id: G7V8S1
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS09275
gene id: 580340:TLIE_RS09275
uniprot id: G7V8Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

580340:TLIE RS00690
gene id: 580340:TLIE_RS00690
uniprot id: G7V5X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

580340:TLIE RS03860
gene id: 580340:TLIE_RS03860
uniprot id: G7V9D8
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

580340:TLIE RS02875
gene id: 580340:TLIE_RS02875
uniprot id: G7V8D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

580340:TLIE RS07140
gene id: 580340:TLIE_RS07140
uniprot id: G7V6J4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS00860
gene id: 580340:TLIE_RS00860
uniprot id: G7V685
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

580340:TLIE RS06875
gene id: 580340:TLIE_RS06875
uniprot id: G7V670
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

580340:TLIE RS02080
gene id: 580340:TLIE_RS02080
uniprot id: G7V7J0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS06350
gene id: 580340:TLIE_RS06350
uniprot id: G7V5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

580340:TLIE RS08450
gene id: 580340:TLIE_RS08450
uniprot id: G7V7V4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

580340:TLIE RS03370
gene id: 580340:TLIE_RS03370
uniprot id: G7V8V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

580340:TLIE RS08795
gene id: 580340:TLIE_RS08795
uniprot id: G7V895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

580340:TLIE RS02695
gene id: 580340:TLIE_RS02695
uniprot id: G7V825
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

580340:TLIE RS01985
gene id: 580340:TLIE_RS01985
uniprot id: G7V7H1
names: Similarity
messages: Belongs to the class-I fumarase family.

580340:TLIE RS06105
gene id: 580340:TLIE_RS06105
uniprot id: G7V5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

580340:TLIE RS03820
gene id: 580340:TLIE_RS03820
uniprot id: G7V9B1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

580340:TLIE RS02500
gene id: 580340:TLIE_RS02500
uniprot id: G7V7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

580340:TLIE RS04495
gene id: 580340:TLIE_RS04495
uniprot id: G7V9Q7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

580340:TLIE RS00340
gene id: 580340:TLIE_RS00340
uniprot id: G7V5I6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

580340:TLIE RS07940
gene id: 580340:TLIE_RS07940
uniprot id: G7V7D7
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04010
gene id: 580340:TLIE_RS04010
uniprot id: G7V9G7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

580340:TLIE RS02710
gene id: 580340:TLIE_RS02710
uniprot id: G7V828
names: Similarity
messages: Belongs to the DprA/Smf family.

580340:TLIE RS05025
gene id: 580340:TLIE_RS05025
uniprot id: G7VA07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

580340:TLIE RS05355
gene id: 580340:TLIE_RS05355
uniprot id: G7VA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

580340:TLIE RS09335
gene id: 580340:TLIE_RS09335
uniprot id: G7V8Z7
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS08640
gene id: 580340:TLIE_RS08640
uniprot id: G7V865
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

580340:TLIE RS09260
gene id: 580340:TLIE_RS09260
uniprot id: G7V8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580340:TLIE RS07495
gene id: 580340:TLIE_RS07495
uniprot id: G7V6Y3
names: Similarity
messages: Belongs to the AOR/FOR family.

580340:TLIE RS09615
gene id: 580340:TLIE_RS09615
uniprot id: G7V9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

580340:TLIE RS03700
gene id: 580340:TLIE_RS03700
uniprot id: G7V987
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

580340:TLIE RS09295
gene id: 580340:TLIE_RS09295
uniprot id: G7V8Z0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

580340:TLIE RS06495
gene id: 580340:TLIE_RS06495
uniprot id: G7V5S4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

580340:TLIE RS01780
gene id: 580340:TLIE_RS01780
uniprot id: G7V758
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS01250
gene id: 580340:TLIE_RS01250
uniprot id: G7V6M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

580340:TLIE RS09225
gene id: 580340:TLIE_RS09225
uniprot id: G7V8X7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

580340:TLIE RS09490
gene id: 580340:TLIE_RS09490
uniprot id: G7V922
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580340:TLIE RS06455
gene id: 580340:TLIE_RS06455
uniprot id: G7V5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

580340:TLIE RS07840
gene id: 580340:TLIE_RS07840
uniprot id: G7V7B9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

580340:TLIE RS08385
gene id: 580340:TLIE_RS08385
uniprot id: G7V7U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

580340:TLIE RS07080
gene id: 580340:TLIE_RS07080
uniprot id: G7V6I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

580340:TLIE RS09450
gene id: 580340:TLIE_RS09450
uniprot id: G7V914
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

580340:TLIE RS06075
gene id: 580340:TLIE_RS06075
uniprot id: G7V5C3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

580340:TLIE RS00820
gene id: 580340:TLIE_RS00820
uniprot id: G7V601
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

580340:TLIE RS05160
gene id: 580340:TLIE_RS05160
uniprot id: G7VA34
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

580340:TLIE RS03710
gene id: 580340:TLIE_RS03710
uniprot id: G7V990
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00190
gene id: 580340:TLIE_RS00190
uniprot id: G7V5F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

580340:TLIE RS06120
gene id: 580340:TLIE_RS06120
uniprot id: G7V5D2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

580340:TLIE RS09000
gene id: 580340:TLIE_RS09000
uniprot id: G7V8K6
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS08040
gene id: 580340:TLIE_RS08040
uniprot id: G7V7F7
names: Similarity
messages: Belongs to the AOR/FOR family.

580340:TLIE RS03655
gene id: 580340:TLIE_RS03655
uniprot id: G7V981
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

580340:TLIE RS06420
gene id: 580340:TLIE_RS06420
uniprot id: G7V5Q9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

580340:TLIE RS03080
gene id: 580340:TLIE_RS03080
uniprot id: G7V8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

580340:TLIE RS05945
gene id: 580340:TLIE_RS05945
uniprot id: G7V597
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

580340:TLIE RS00720
gene id: 580340:TLIE_RS00720
uniprot id: G7V5Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

580340:TLIE RS01115
gene id: 580340:TLIE_RS01115
uniprot id: G7V6D6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS06985
gene id: 580340:TLIE_RS06985
uniprot id: G7V6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

580340:TLIE RS02560
gene id: 580340:TLIE_RS02560
uniprot id: G7V7Z9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS03095
gene id: 580340:TLIE_RS03095
uniprot id: G7V8P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

580340:TLIE RS09755
gene id: 580340:TLIE_RS09755
uniprot id: G7VAF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580340:TLIE RS06040
gene id: 580340:TLIE_RS06040
uniprot id: G7V5B5
names: Similarity
messages: Belongs to the acylphosphatase family.

580340:TLIE RS04605
gene id: 580340:TLIE_RS04605
uniprot id: G7V9S8
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06725
gene id: 580340:TLIE_RS06725
uniprot id: G7V640
names: Similarity
messages: Belongs to the HypD family.

580340:TLIE RS03025
gene id: 580340:TLIE_RS03025
uniprot id: G7V8G1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

580340:TLIE RS05430
gene id: 580340:TLIE_RS05430
uniprot id: G7VA89
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

580340:TLIE RS06500
gene id: 580340:TLIE_RS06500
uniprot id: G7V5S5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

580340:TLIE RS01855
gene id: 580340:TLIE_RS01855
uniprot id: G7V773
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04005
gene id: 580340:TLIE_RS04005
uniprot id: G7V9G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

580340:TLIE RS00045
gene id: 580340:TLIE_RS00045
uniprot id: G7V554
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS04965
gene id: 580340:TLIE_RS04965
uniprot id: G7V9Z5
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS03390
gene id: 580340:TLIE_RS03390
uniprot id: G7V8V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

580340:TLIE RS05795
gene id: 580340:TLIE_RS05795
uniprot id: G7V569
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580340:TLIE RS00260
gene id: 580340:TLIE_RS00260
uniprot id: G7V5H0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

580340:TLIE RS03705
gene id: 580340:TLIE_RS03705
uniprot id: G7V988
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

580340:TLIE RS05150
gene id: 580340:TLIE_RS05150
uniprot id: G7VA32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

580340:TLIE RS07215
gene id: 580340:TLIE_RS07215
uniprot id: G7V6K4
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS04995
gene id: 580340:TLIE_RS04995
uniprot id: G7VA01
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

580340:TLIE RS05660
gene id: 580340:TLIE_RS05660
uniprot id: G7VAC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS00460
gene id: 580340:TLIE_RS00460
uniprot id: G7V5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

580340:TLIE RS06445
gene id: 580340:TLIE_RS06445
uniprot id: G7V5R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

580340:TLIE RS05350
gene id: 580340:TLIE_RS05350
uniprot id: G7VA72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

580340:TLIE RS04020
gene id: 580340:TLIE_RS04020
uniprot id: G7V9G9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

580340:TLIE RS08515
gene id: 580340:TLIE_RS08515
uniprot id: G7V840
names: Similarity
messages: Belongs to the ComB family.

580340:TLIE RS00270
gene id: 580340:TLIE_RS00270
uniprot id: G7V5H2
names: Similarity
messages: Belongs to the GSP E family.

580340:TLIE RS06890
gene id: 580340:TLIE_RS06890
uniprot id: G7V673
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

580340:TLIE RS01185
gene id: 580340:TLIE_RS01185
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS07820
gene id: 580340:TLIE_RS07820
uniprot id: G7V7B6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

580340:TLIE RS02960
gene id: 580340:TLIE_RS02960
uniprot id: G7V8E8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS09190
gene id: 580340:TLIE_RS09190
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS00050
gene id: 580340:TLIE_RS00050
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS03925
gene id: 580340:TLIE_RS03925
uniprot id: G7V9F0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS03210
gene id: 580340:TLIE_RS03210
uniprot id: G7V8S0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

580340:TLIE RS00440
gene id: 580340:TLIE_RS00440
uniprot id: G7V5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

580340:TLIE RS01770
gene id: 580340:TLIE_RS01770
uniprot id: G7V756
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

580340:TLIE RS00400
gene id: 580340:TLIE_RS00400
uniprot id: G7V5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS04730
gene id: 580340:TLIE_RS04730
uniprot id: G7V9V3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

580340:TLIE RS07945
gene id: 580340:TLIE_RS07945
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS05170
gene id: 580340:TLIE_RS05170
uniprot id: G7VA36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

580340:TLIE RS05035
gene id: 580340:TLIE_RS05035
uniprot id: G7VA09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

580340:TLIE RS07160
gene id: 580340:TLIE_RS07160
uniprot id: G7V6J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

580340:TLIE RS05400
gene id: 580340:TLIE_RS05400
uniprot id: G7VA83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

580340:TLIE RS02160
gene id: 580340:TLIE_RS02160
uniprot id: G7V7K3
names: Similarity
messages: Belongs to the NadC/ModD family.

580340:TLIE RS04360
gene id: 580340:TLIE_RS04360
uniprot id: G7V9N5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

580340:TLIE RS03410
gene id: 580340:TLIE_RS03410
uniprot id: G7V8V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

580340:TLIE RS00135
gene id: 580340:TLIE_RS00135
uniprot id: G7V5E5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS07855
gene id: 580340:TLIE_RS07855
uniprot id: G7V7C2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

580340:TLIE RS01075
gene id: 580340:TLIE_RS01075
uniprot id: G7V6C7
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

580340:TLIE RS01070
gene id: 580340:TLIE_RS01070
uniprot id: G7V6C6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

580340:TLIE RS07480
gene id: 580340:TLIE_RS07480
uniprot id: G7V6Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS03420
gene id: 580340:TLIE_RS03420
uniprot id: G7V8W1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

580340:TLIE RS07130
gene id: 580340:TLIE_RS07130
uniprot id: G7V6J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

580340:TLIE RS08240
gene id: 580340:TLIE_RS08240
uniprot id: G7V7Q9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

580340:TLIE RS05685
gene id: 580340:TLIE_RS05685
uniprot id: G7VAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

580340:TLIE RS09990
gene id: 580340:TLIE_RS09990
uniprot id: G7V9X3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

580340:TLIE RS09475
gene id: 580340:TLIE_RS09475
uniprot id: G7V919
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS02825
gene id: 580340:TLIE_RS02825
uniprot id: G7V8C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

580340:TLIE RS02855
gene id: 580340:TLIE_RS02855
uniprot id: G7V8C8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

580340:TLIE RS04615
gene id: 580340:TLIE_RS04615
uniprot id: G7V9T0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

580340:TLIE RS02170
gene id: 580340:TLIE_RS02170
uniprot id: G7V7K5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

580340:TLIE RS04690
gene id: 580340:TLIE_RS04690
uniprot id: G7V9U5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

580340:TLIE RS05930
gene id: 580340:TLIE_RS05930
uniprot id: G7V594
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

580340:TLIE RS00350
gene id: 580340:TLIE_RS00350
uniprot id: G7V5I8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

580340:TLIE RS09625
gene id: 580340:TLIE_RS09625
uniprot id: G7V9C1
names: Similarity
messages: Belongs to the IMPACT family.

580340:TLIE RS01610
gene id: 580340:TLIE_RS01610
uniprot id: G7V726
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00980
gene id: 580340:TLIE_RS00980
uniprot id: G7V6A8
names: Similarity
messages: Belongs to the EutP/PduV family.

580340:TLIE RS03855
gene id: 580340:TLIE_RS03855
uniprot id: G7V9D7
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

580340:TLIE RS07295
gene id: 580340:TLIE_RS07295
uniprot id: G7V6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

580340:TLIE RS08710
gene id: 580340:TLIE_RS08710
uniprot id: G7V879
names: Similarity
messages: Belongs to the UPF0261 family.

580340:TLIE RS00305
gene id: 580340:TLIE_RS00305
uniprot id: G7V5H9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

580340:TLIE RS01400
gene id: 580340:TLIE_RS01400
uniprot id: G7V6Q8
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

580340:TLIE RS01845
gene id: 580340:TLIE_RS01845
uniprot id: G7V771
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

580340:TLIE RS08920
gene id: 580340:TLIE_RS08920
uniprot id: G7V8J0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS00300
gene id: 580340:TLIE_RS00300
uniprot id: G7V5H8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

580340:TLIE RS07320
gene id: 580340:TLIE_RS07320
uniprot id: G7V6U9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

580340:TLIE RS08780
gene id: 580340:TLIE_RS08780
uniprot id: G7V892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

580340:TLIE RS02985
gene id: 580340:TLIE_RS02985
uniprot id: G7V8F3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04565
gene id: 580340:TLIE_RS04565
uniprot id: G7V9S1
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

580340:TLIE RS07540
gene id: 580340:TLIE_RS07540
uniprot id: G7V6Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

580340:TLIE RS01270
gene id: 580340:TLIE_RS01270
uniprot id: G7V6N3
names: Similarity
messages: Belongs to the DapB family.

580340:TLIE RS05205
gene id: 580340:TLIE_RS05205
uniprot id: G7VA43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04670
gene id: 580340:TLIE_RS04670
uniprot id: G7V9U1
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05880
gene id: 580340:TLIE_RS05880
uniprot id: G7V585
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

580340:TLIE RS04695
gene id: 580340:TLIE_RS04695
uniprot id: G7V9U6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

580340:TLIE RS04470
gene id: 580340:TLIE_RS04470
uniprot id: G7V9Q2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

580340:TLIE RS00010
gene id: 580340:TLIE_RS00010
uniprot id: G7V547
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

580340:TLIE RS03630
gene id: 580340:TLIE_RS03630
uniprot id: G7V976
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

580340:TLIE RS03765
gene id: 580340:TLIE_RS03765
uniprot id: G7V9A1
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS02265
gene id: 580340:TLIE_RS02265
uniprot id: G7V7M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

580340:TLIE RS00285
gene id: 580340:TLIE_RS00285
uniprot id: G7V5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

580340:TLIE RS00730
gene id: 580340:TLIE_RS00730
uniprot id: G7V5Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

580340:TLIE RS08865
gene id: 580340:TLIE_RS08865
uniprot id: G7V8H9
names: Similarity
messages: Belongs to the TPP enzyme family.

580340:TLIE RS03475
gene id: 580340:TLIE_RS03475
uniprot id: G7V945
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06245
gene id: 580340:TLIE_RS06245
uniprot id: G7V5M6
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS03435
gene id: 580340:TLIE_RS03435
uniprot id: G7V8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

580340:TLIE RS05690
gene id: 580340:TLIE_RS05690
uniprot id: G7VAD2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

580340:TLIE RS00025
gene id: 580340:TLIE_RS00025
uniprot id: G7V550
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

580340:TLIE RS03340
gene id: 580340:TLIE_RS03340
uniprot id: G7V8U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

580340:TLIE RS06990
gene id: 580340:TLIE_RS06990
uniprot id: G7V6G5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

580340:TLIE RS06465
gene id: 580340:TLIE_RS06465
uniprot id: G7V5R8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

580340:TLIE RS06860
gene id: 580340:TLIE_RS06860
uniprot id: G7V667
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS06180
gene id: 580340:TLIE_RS06180
uniprot id: G7V5L5
names: Similarity
messages: Belongs to the CdaR family.

580340:TLIE RS03090
gene id: 580340:TLIE_RS03090
uniprot id: G7V8P6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

580340:TLIE RS08750
gene id: 580340:TLIE_RS08750
uniprot id: G7V886
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05100
gene id: 580340:TLIE_RS05100
uniprot id: G7VA22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

580340:TLIE RS02510
gene id: 580340:TLIE_RS02510
uniprot id: G7V7Y9
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS08250
gene id: 580340:TLIE_RS08250
uniprot id: G7V7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

580340:TLIE RS08800
gene id: 580340:TLIE_RS08800
uniprot id: G7V896
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS00105
gene id: 580340:TLIE_RS00105
uniprot id: G7V5D9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

580340:TLIE RS04800
gene id: 580340:TLIE_RS04800
uniprot id: G7V9W6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

580340:TLIE RS02995
gene id: 580340:TLIE_RS02995
uniprot id: G7V8F5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS01650
gene id: 580340:TLIE_RS01650
uniprot id: G7V734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS05585
gene id: 580340:TLIE_RS05585
uniprot id: G7VAB1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

580340:TLIE RS06855
gene id: 580340:TLIE_RS06855
uniprot id: G7V666
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

580340:TLIE RS01850
gene id: 580340:TLIE_RS01850
uniprot id: G7V772
names: Similarity
messages: Belongs to the arginase family.

580340:TLIE RS07770
gene id: 580340:TLIE_RS07770
uniprot id: G7V7A7
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

580340:TLIE RS05440
gene id: 580340:TLIE_RS05440
uniprot id: G7VA91
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the LacAB/RpiB family.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

580340:TLIE RS02530
gene id: 580340:TLIE_RS02530
uniprot id: G7V7Z3
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS03590
gene id: 580340:TLIE_RS03590
uniprot id: G7V968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

580340:TLIE RS06405
gene id: 580340:TLIE_RS06405
uniprot id: G7V5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

580340:TLIE RS05370
gene id: 580340:TLIE_RS05370
uniprot id: G7VA77
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

580340:TLIE RS05935
gene id: 580340:TLIE_RS05935
uniprot id: G7V595
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

580340:TLIE RS05140
gene id: 580340:TLIE_RS05140
uniprot id: G7VA30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS03930
gene id: 580340:TLIE_RS03930
uniprot id: G7V9F1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

580340:TLIE RS06385
gene id: 580340:TLIE_RS06385
uniprot id: G7V5Q2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

580340:TLIE RS09030
gene id: 580340:TLIE_RS09030
uniprot id: G7V8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

580340:TLIE RS08620
gene id: 580340:TLIE_RS08620
uniprot id: G7V861
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580340:TLIE RS05390
gene id: 580340:TLIE_RS05390
uniprot id: G7VA81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

580340:TLIE RS00545
gene id: 580340:TLIE_RS00545
uniprot id: G7V5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

580340:TLIE RS07630
gene id: 580340:TLIE_RS07630
uniprot id: G7V708
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS03805
gene id: 580340:TLIE_RS03805
uniprot id: G7V9A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

580340:TLIE RS04105
gene id: 580340:TLIE_RS04105
uniprot id: G7V9I3
names: Similarity
messages: Belongs to the peptidase S58 family.

580340:TLIE RS02870
gene id: 580340:TLIE_RS02870
uniprot id: G7V8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

580340:TLIE RS08175
gene id: 580340:TLIE_RS08175
uniprot id: G7V7P5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS01505
gene id: 580340:TLIE_RS01505
uniprot id: G7V6S8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

580340:TLIE RS04975
gene id: 580340:TLIE_RS04975
uniprot id: G7V9Z7
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

580340:TLIE RS08130
gene id: 580340:TLIE_RS08130
uniprot id: G7V7N7
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS09815
gene id: 580340:TLIE_RS09815
uniprot id: G7VAG7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS00245
gene id: 580340:TLIE_RS00245
uniprot id: G7V5G7
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

580340:TLIE RS05950
gene id: 580340:TLIE_RS05950
uniprot id: G7V598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

580340:TLIE RS07645
gene id: 580340:TLIE_RS07645
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS01545
gene id: 580340:TLIE_RS01545
uniprot id: G7V6T7
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

580340:TLIE RS03040
gene id: 580340:TLIE_RS03040
uniprot id: G7V8G4
names: Similarity
messages: Belongs to the aspartokinase family.

580340:TLIE RS03325
gene id: 580340:TLIE_RS03325
uniprot id: G7V8U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

580340:TLIE RS06775
gene id: 580340:TLIE_RS06775
uniprot id: G7V650
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

580340:TLIE RS04485
gene id: 580340:TLIE_RS04485
uniprot id: G7V9Q5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

580340:TLIE RS09405
gene id: 580340:TLIE_RS09405
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS03660
gene id: 580340:TLIE_RS03660
uniprot id: G7V982
names: Subcellular Location Annotation
messages: Periplasm

580340:TLIE RS09885
gene id: 580340:TLIE_RS09885
uniprot id: G7V6U0
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS02425
gene id: 580340:TLIE_RS02425
uniprot id: G7V7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS03480
gene id: 580340:TLIE_RS03480
uniprot id: G7V946
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS00565
gene id: 580340:TLIE_RS00565
uniprot id: G7V5V1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

580340:TLIE RS00335
gene id: 580340:TLIE_RS00335
uniprot id: G7V5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

580340:TLIE RS08880
gene id: 580340:TLIE_RS08880
uniprot id: G7V8I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

580340:TLIE RS09460
gene id: 580340:TLIE_RS09460
uniprot id: G7V916
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

580340:TLIE RS07615
gene id: 580340:TLIE_RS07615
uniprot id: G7V705
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

580340:TLIE RS09850
gene id: 580340:TLIE_RS09850
uniprot id: G7V5I9
names: Similarity
messages: Belongs to the bacterial flagellin family.

580340:TLIE RS06960
gene id: 580340:TLIE_RS06960
uniprot id: G7V6F9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

580340:TLIE RS02690
gene id: 580340:TLIE_RS02690
uniprot id: G7V824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

580340:TLIE RS09745
gene id: 580340:TLIE_RS09745
uniprot id: G7VAF4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

580340:TLIE RS05900
gene id: 580340:TLIE_RS05900
uniprot id: G7V589
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

580340:TLIE RS05970
gene id: 580340:TLIE_RS05970
uniprot id: G7V5A2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

580340:TLIE RS05720
gene id: 580340:TLIE_RS05720
uniprot id: G7VAD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

580340:TLIE RS07620
gene id: 580340:TLIE_RS07620
uniprot id: G7V706
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

580340:TLIE RS08065
gene id: 580340:TLIE_RS08065
uniprot id: G7V7G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580340:TLIE RS02070
gene id: 580340:TLIE_RS02070
uniprot id: G7V7I8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

580340:TLIE RS04465
gene id: 580340:TLIE_RS04465
uniprot id: G7V9Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

580340:TLIE RS04160
gene id: 580340:TLIE_RS04160
uniprot id: G7V9J4
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

580340:TLIE RS04490
gene id: 580340:TLIE_RS04490
uniprot id: G7V9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

580340:TLIE RS02450
gene id: 580340:TLIE_RS02450
uniprot id: G7V7X7
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS10280
gene id: 580340:TLIE_RS10280
uniprot id: G7V7Z2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

580340:TLIE RS05215
gene id: 580340:TLIE_RS05215
uniprot id: G7VA45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

580340:TLIE RS01355
gene id: 580340:TLIE_RS01355
uniprot id: G7V6Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

580340:TLIE RS09735
gene id: 580340:TLIE_RS09735
uniprot id: G7VAF2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

580340:TLIE RS05245
gene id: 580340:TLIE_RS05245
uniprot id: G7VA51
names: Similarity
messages: Belongs to the leucine-binding protein family.

580340:TLIE RS07730
gene id: 580340:TLIE_RS07730
uniprot id: G7V799
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

580340:TLIE RS01510
gene id: 580340:TLIE_RS01510
uniprot id: G7V6T0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

580340:TLIE RS01405
gene id: 580340:TLIE_RS01405
uniprot id: G7V6Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

580340:TLIE RS02980
gene id: 580340:TLIE_RS02980
uniprot id: G7V8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

580340:TLIE RS03985
gene id: 580340:TLIE_RS03985
uniprot id: G7V9G2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

580340:TLIE RS04680
gene id: 580340:TLIE_RS04680
uniprot id: G7V9U3
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

580340:TLIE RS05810
gene id: 580340:TLIE_RS05810
uniprot id: G7V572
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS07875
gene id: 580340:TLIE_RS07875
uniprot id: G7V7C6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

580340:TLIE RS06095
gene id: 580340:TLIE_RS06095
uniprot id: G7V5C7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS03555
gene id: 580340:TLIE_RS03555
uniprot id: G7V961
names: Similarity
messages: Belongs to the leucine-binding protein family.

580340:TLIE RS03495
gene id: 580340:TLIE_RS03495
uniprot id: G7V949
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS08000
gene id: 580340:TLIE_RS08000
uniprot id: G7V7E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

580340:TLIE RS08960
gene id: 580340:TLIE_RS08960
uniprot id: G7V8J8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

580340:TLIE RS03365
gene id: 580340:TLIE_RS03365
uniprot id: G7V8V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

580340:TLIE RS04185
gene id: 580340:TLIE_RS04185
uniprot id: G7V9J9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

580340:TLIE RS02270
gene id: 580340:TLIE_RS02270
uniprot id: G7V7M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

580340:TLIE RS00615
gene id: 580340:TLIE_RS00615
uniprot id: G7V5W1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580340:TLIE RS06595
gene id: 580340:TLIE_RS06595
uniprot id: G7V617
names: Similarity
messages: Belongs to the HypE family.

580340:TLIE RS07065
gene id: 580340:TLIE_RS07065
uniprot id: G7V6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

580340:TLIE RS09175
gene id: 580340:TLIE_RS09175
uniprot id: G7V8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

580340:TLIE RS01795
gene id: 580340:TLIE_RS01795
uniprot id: G7V761
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

580340:TLIE RS05115
gene id: 580340:TLIE_RS05115
uniprot id: G7VA25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

580340:TLIE RS05375
gene id: 580340:TLIE_RS05375
uniprot id: G7VA78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS01255
gene id: 580340:TLIE_RS01255
uniprot id: G7V6M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

580340:TLIE RS02185
gene id: 580340:TLIE_RS02185
uniprot id: G7V7K8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

580340:TLIE RS02130
gene id: 580340:TLIE_RS02130
uniprot id: G7V7J7
names: Similarity
messages: Belongs to the peptidase U62 family.

580340:TLIE RS03450
gene id: 580340:TLIE_RS03450
uniprot id: G7V8W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

580340:TLIE RS06970
gene id: 580340:TLIE_RS06970
uniprot id: G7V6G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

580340:TLIE RS06070
gene id: 580340:TLIE_RS06070
uniprot id: G7V5C2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

580340:TLIE RS01195
gene id: 580340:TLIE_RS01195
uniprot id: G7V6E7
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

580340:TLIE RS06060
gene id: 580340:TLIE_RS06060
uniprot id: G7V5C0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

580340:TLIE RS04150
gene id: 580340:TLIE_RS04150
uniprot id: G7V9J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS01580
gene id: 580340:TLIE_RS01580
uniprot id: G7V6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

580340:TLIE RS02440
gene id: 580340:TLIE_RS02440
uniprot id: G7V7X5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

580340:TLIE RS03380
gene id: 580340:TLIE_RS03380
uniprot id: G7V8V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

580340:TLIE RS08680
gene id: 580340:TLIE_RS08680
uniprot id: G7V873
names: Subcellular Location Annotation
messages: Cytoplasm

580340:TLIE RS01290
gene id: 580340:TLIE_RS01290
uniprot id: G7V6N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

580340:TLIE RS08945
gene id: 580340:TLIE_RS08945
uniprot id: G7V8J5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

580340:TLIE RS08890
gene id: 580340:TLIE_RS08890
uniprot id: G7V8I4
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS02190
gene id: 580340:TLIE_RS02190
uniprot id: G7V7K9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580340:TLIE RS05580
gene id: 580340:TLIE_RS05580
uniprot id: G7VAB0
names: Similarity
messages: Belongs to the FBPase class 2 family.

580340:TLIE RS09705
gene id: 580340:TLIE_RS09705
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS00845
gene id: 580340:TLIE_RS00845
uniprot id: G7V682
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00715
gene id: 580340:TLIE_RS00715
uniprot id: G7V5Y1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580340:TLIE RS05260
gene id: 580340:TLIE_RS05260
uniprot id: G7VA54
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS09555
gene id: 580340:TLIE_RS09555
uniprot id: G7V934
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

580340:TLIE RS08465
gene id: 580340:TLIE_RS08465
uniprot id: G7V830
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS07520
gene id: 580340:TLIE_RS07520
uniprot id: G7V6Y8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580340:TLIE RS06510
gene id: 580340:TLIE_RS06510
uniprot id: G7V5S7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

580340:TLIE RS06505
gene id: 580340:TLIE_RS06505
uniprot id: G7V5S6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS03130
gene id: 580340:TLIE_RS03130
uniprot id: G7V8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

580340:TLIE RS01220
gene id: 580340:TLIE_RS01220
uniprot id: G7V6F2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

580340:TLIE RS06025
gene id: 580340:TLIE_RS06025
uniprot id: G7V5B2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

580340:TLIE RS00740
gene id: 580340:TLIE_RS00740
uniprot id: G7V5Y5
names: Similarity
messages: Belongs to the IlvD/Edd family.

580340:TLIE RS03940
gene id: 580340:TLIE_RS03940
uniprot id: G7V9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

580340:TLIE RS08145
gene id: 580340:TLIE_RS08145
uniprot id: G7V7P0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

580340:TLIE RS06545
gene id: 580340:TLIE_RS06545
uniprot id: G7V607
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

580340:TLIE RS05730
gene id: 580340:TLIE_RS05730
uniprot id: G7VAE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

580340:TLIE RS06450
gene id: 580340:TLIE_RS06450
uniprot id: G7V5R5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

580340:TLIE RS05180
gene id: 580340:TLIE_RS05180
uniprot id: G7VA38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

580340:TLIE RS00960
gene id: 580340:TLIE_RS00960
uniprot id: G7V6A4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

580340:TLIE RS07420
gene id: 580340:TLIE_RS07420
uniprot id: G7V6W8
names: Similarity
messages: Belongs to the asparaginase 1 family.

580340:TLIE RS05960
gene id: 580340:TLIE_RS05960
uniprot id: G7V5A0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

580340:TLIE RS05165
gene id: 580340:TLIE_RS05165
uniprot id: G7VA35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

580340:TLIE RS00880
gene id: 580340:TLIE_RS00880
uniprot id: G7V689
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS00015
gene id: 580340:TLIE_RS00015
uniprot id: G7V548
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

580340:TLIE RS03330
gene id: 580340:TLIE_RS03330
uniprot id: G7V8U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

580340:TLIE RS07100
gene id: 580340:TLIE_RS07100
uniprot id: G7V6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

580340:TLIE RS03170
gene id: 580340:TLIE_RS03170
uniprot id: G7V8R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS06950
gene id: 580340:TLIE_RS06950
uniprot id: G7V6F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

580340:TLIE RS04860
gene id: 580340:TLIE_RS04860
uniprot id: G7V9X6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

580340:TLIE RS01350
gene id: 580340:TLIE_RS01350
uniprot id: G7V6P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

580340:TLIE RS02145
gene id: 580340:TLIE_RS02145
uniprot id: G7V7K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

580340:TLIE RS06080
gene id: 580340:TLIE_RS06080
uniprot id: G7V5C4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

580340:TLIE RS08910
gene id: 580340:TLIE_RS08910
uniprot id: G7V8I8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

580340:TLIE RS08280
gene id: 580340:TLIE_RS08280
uniprot id: G7V7R9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

580340:TLIE RS09960
gene id: 580340:TLIE_RS09960
uniprot id: G7V9B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

580340:TLIE RS02540
gene id: 580340:TLIE_RS02540
uniprot id: G7V7Z5
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS02740
gene id: 580340:TLIE_RS02740
uniprot id: G7V8A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

580340:TLIE RS03360
gene id: 580340:TLIE_RS03360
uniprot id: G7V8U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

580340:TLIE RS00250
gene id: 580340:TLIE_RS00250
uniprot id: G7V5G8
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

580340:TLIE RS09520
gene id: 580340:TLIE_RS09520
uniprot id: G7V927
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05005
gene id: 580340:TLIE_RS05005
uniprot id: G7VA03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

580340:TLIE RS07290
gene id: 580340:TLIE_RS07290
uniprot id: G7V6L9
names: Similarity
messages: Belongs to the CtsR family.

580340:TLIE RS03115
gene id: 580340:TLIE_RS03115
uniprot id: G7V8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

580340:TLIE RS09270
gene id: 580340:TLIE_RS09270
uniprot id: G7V8Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

580340:TLIE RS07830
gene id: 580340:TLIE_RS07830
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS01730
gene id: 580340:TLIE_RS01730
uniprot id: G7V748
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS09305
gene id: 580340:TLIE_RS09305
uniprot id: G7V8Z1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

580340:TLIE RS04480
gene id: 580340:TLIE_RS04480
uniprot id: G7V9Q4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS02260
gene id: 580340:TLIE_RS02260
uniprot id: G7V7L9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

580340:TLIE RS07810
gene id: 580340:TLIE_RS07810
uniprot id: G7V7B4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

580340:TLIE RS03625
gene id: 580340:TLIE_RS03625
uniprot id: G7V975
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

580340:TLIE RS06885
gene id: 580340:TLIE_RS06885
uniprot id: G7V672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

580340:TLIE RS03600
gene id: 580340:TLIE_RS03600
uniprot id: G7V970
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

580340:TLIE RS01315
gene id: 580340:TLIE_RS01315
uniprot id: G7V6P2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

580340:TLIE RS04325
gene id: 580340:TLIE_RS04325
uniprot id: G7V9M8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS03445
gene id: 580340:TLIE_RS03445
uniprot id: G7V8W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

580340:TLIE RS07000
gene id: 580340:TLIE_RS07000
uniprot id: G7V6G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

580340:TLIE RS07005
gene id: 580340:TLIE_RS07005
uniprot id: G7V6G8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

580340:TLIE RS02045
gene id: 580340:TLIE_RS02045
uniprot id: G7V7I3
names: Similarity
messages: Belongs to the UPF0597 family.

580340:TLIE RS04960
gene id: 580340:TLIE_RS04960
uniprot id: G7V9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

580340:TLIE RS03895
gene id: 580340:TLIE_RS03895
uniprot id: G7V9E5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

580340:TLIE RS04665
gene id: 580340:TLIE_RS04665
uniprot id: G7V9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

580340:TLIE RS04600
gene id: 580340:TLIE_RS04600
uniprot id: G7V9S7
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS09600
gene id: 580340:TLIE_RS09600
uniprot id: G7V942
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS00930
gene id: 580340:TLIE_RS00930
uniprot id: G7V699
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS03295
gene id: 580340:TLIE_RS03295
uniprot id: G7V8T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

580340:TLIE RS05265
gene id: 580340:TLIE_RS05265
uniprot id: G7VA55
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05000
gene id: 580340:TLIE_RS05000
uniprot id: G7VA02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

580340:TLIE RS07910
gene id: 580340:TLIE_RS07910
uniprot id: G7V7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

580340:TLIE RS00985
gene id: 580340:TLIE_RS00985
uniprot id: G7V6A9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

580340:TLIE RS06000
gene id: 580340:TLIE_RS06000
uniprot id: G7V5A7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

580340:TLIE RS08745
gene id: 580340:TLIE_RS08745
uniprot id: G7V885
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS03335
gene id: 580340:TLIE_RS03335
uniprot id: G7V8U4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

580340:TLIE RS08895
gene id: 580340:TLIE_RS08895
uniprot id: G7V8I5
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06360
gene id: 580340:TLIE_RS06360
uniprot id: G7V5P7
names: Similarity
messages: Belongs to the AOR/FOR family.

580340:TLIE RS05020
gene id: 580340:TLIE_RS05020
uniprot id: G7VA06
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS06740
gene id: 580340:TLIE_RS06740
uniprot id: G7V643
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

580340:TLIE RS03975
gene id: 580340:TLIE_RS03975
uniprot id: G7V9G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

580340:TLIE RS06280
gene id: 580340:TLIE_RS06280
uniprot id: G7V5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS04715
gene id: 580340:TLIE_RS04715
uniprot id: G7V9V0
names: Caution
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

580340:TLIE RS04440
gene id: 580340:TLIE_RS04440
uniprot id: G7V9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

580340:TLIE RS03580
gene id: 580340:TLIE_RS03580
uniprot id: G7V966
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06480
gene id: 580340:TLIE_RS06480
uniprot id: G7V5S1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

580340:TLIE RS04130
gene id: 580340:TLIE_RS04130
uniprot id: G7V9I8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

580340:TLIE RS01445
gene id: 580340:TLIE_RS01445
uniprot id: G7V6R7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

580340:TLIE RS00940
gene id: 580340:TLIE_RS00940
uniprot id: G7V6A1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

580340:TLIE RS03280
gene id: 580340:TLIE_RS03280
uniprot id: G7V8T3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

580340:TLIE RS07690
gene id: 580340:TLIE_RS07690
uniprot id: G7V718
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

580340:TLIE RS03320
gene id: 580340:TLIE_RS03320
uniprot id: G7V8U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

580340:TLIE RS03815
gene id: 580340:TLIE_RS03815
uniprot id: G7V9B0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

580340:TLIE RS05555
gene id: 580340:TLIE_RS05555
uniprot id: G7VAA5
names: Similarity
messages: Belongs to the Nth/MutY family.

580340:TLIE RS06490
gene id: 580340:TLIE_RS06490
uniprot id: G7V5S3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

580340:TLIE RS00830
gene id: 580340:TLIE_RS00830
uniprot id: G7V603
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

580340:TLIE RS00780
gene id: 580340:TLIE_RS00780
uniprot id: G7V5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS05470
gene id: 580340:TLIE_RS05470
uniprot id: G7VA97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

580340:TLIE RS08340
gene id: 580340:TLIE_RS08340
uniprot id: G7V7T2
names: Similarity
messages: Belongs to the peptidase A31 family.

580340:TLIE RS08885
gene id: 580340:TLIE_RS08885
uniprot id: G7V8I3
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

580340:TLIE RS04705
gene id: 580340:TLIE_RS04705
uniprot id: G7V9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

580340:TLIE RS00595
gene id: 580340:TLIE_RS00595
uniprot id: G7V5V7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

580340:TLIE RS00145
gene id: 580340:TLIE_RS00145
uniprot id: G7V5E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04750
gene id: 580340:TLIE_RS04750
uniprot id: G7V9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

580340:TLIE RS05910
gene id: 580340:TLIE_RS05910
uniprot id: G7V590
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

580340:TLIE RS07740
gene id: 580340:TLIE_RS07740
uniprot id: G7V7A1
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

580340:TLIE RS06225
gene id: 580340:TLIE_RS06225
uniprot id: G7V5M2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

580340:TLIE RS08205
gene id: 580340:TLIE_RS08205
uniprot id: G7V7Q1
names: Similarity
messages: Belongs to the proline racemase family.

580340:TLIE RS01210
gene id: 580340:TLIE_RS01210
uniprot id: G7V6F0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

580340:TLIE RS03550
gene id: 580340:TLIE_RS03550
uniprot id: G7V960
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS01490
gene id: 580340:TLIE_RS01490
uniprot id: G7V6S5
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

580340:TLIE RS07750
gene id: 580340:TLIE_RS07750
uniprot id: G7V7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

580340:TLIE RS08565
gene id: 580340:TLIE_RS08565
uniprot id: G7V850
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04625
gene id: 580340:TLIE_RS04625
uniprot id: G7V9T2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

580340:TLIE RS03830
gene id: 580340:TLIE_RS03830
uniprot id: G7V9B3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

580340:TLIE RS05335
gene id: 580340:TLIE_RS05335
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS04775
gene id: 580340:TLIE_RS04775
uniprot id: G7V9W2
names: Similarity
messages: Belongs to the ribF family.

580340:TLIE RS10275
gene id: 580340:TLIE_RS10275
uniprot id: G7V7Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

580340:TLIE RS03640
gene id: 580340:TLIE_RS03640
uniprot id: G7V978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

580340:TLIE RS08605
gene id: 580340:TLIE_RS08605
uniprot id: G7V858
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS04260
gene id: 580340:TLIE_RS04260
uniprot id: G7V9L5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

580340:TLIE RS08475
gene id: 580340:TLIE_RS08475
uniprot id: G7V832
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS05130
gene id: 580340:TLIE_RS05130
uniprot id: G7VA28
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

580340:TLIE RS08700
gene id: 580340:TLIE_RS08700
uniprot id: G7V877
names: Similarity
messages: Belongs to the RutC family.

580340:TLIE RS08440
gene id: 580340:TLIE_RS08440
uniprot id: G7V7V2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

580340:TLIE RS06650
gene id: 580340:TLIE_RS06650
uniprot id: G7V628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS00150
gene id: 580340:TLIE_RS00150
uniprot id: G7V5E8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580340:TLIE RS04850
gene id: 580340:TLIE_RS04850
uniprot id: G7V9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

580340:TLIE RS04880
gene id: 580340:TLIE_RS04880
uniprot id: G7V9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

580340:TLIE RS03060
gene id: 580340:TLIE_RS03060
uniprot id: G7V8G8
names: Similarity
messages: Belongs to the peptidase A31 family.

580340:TLIE RS06730
gene id: 580340:TLIE_RS06730
uniprot id: G7V641
names: Similarity
messages: Belongs to the HypE family.

580340:TLIE RS09135
gene id: 580340:TLIE_RS09135
uniprot id: G7V8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

580340:TLIE RS06615
gene id: 580340:TLIE_RS06615
uniprot id: G7V621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

580340:TLIE RS08265
gene id: 580340:TLIE_RS08265
uniprot id: G7V7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

580340:TLIE RS01465
gene id: 580340:TLIE_RS01465
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS06290
gene id: 580340:TLIE_RS06290
uniprot id: G7V679
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS00205
gene id: 580340:TLIE_RS00205
uniprot id: G7V5F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

580340:TLIE RS02705
gene id: 580340:TLIE_RS02705
uniprot id: G7V827
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

580340:TLIE RS03900
gene id: 580340:TLIE_RS03900
uniprot id: G7V9E6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

580340:TLIE RS06760
gene id: 580340:TLIE_RS06760
uniprot id: G7V647
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

580340:TLIE RS09740
gene id: 580340:TLIE_RS09740
uniprot id: G7VAF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580340:TLIE RS01995
gene id: 580340:TLIE_RS01995
uniprot id: G7V7H3
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

580340:TLIE RS00130
gene id: 580340:TLIE_RS00130
uniprot id: G7V5E4
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS01425
gene id: 580340:TLIE_RS01425
uniprot id: G7V6R3
names: Similarity
messages: Belongs to the sigma-54 factor family.

580340:TLIE RS04165
gene id: 580340:TLIE_RS04165
uniprot id: G7V9J5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS04710
gene id: 580340:TLIE_RS04710
uniprot id: G7V9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

580340:TLIE RS05460
gene id: 580340:TLIE_RS05460
uniprot id: G7VA95
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

580340:TLIE RS09515
gene id: 580340:TLIE_RS09515
uniprot id: G7V926
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580340:TLIE RS07185
gene id: 580340:TLIE_RS07185
uniprot id: G7V6J9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

580340:TLIE RS07365
gene id: 580340:TLIE_RS07365
uniprot id: G7V6V7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

580340:TLIE RS09545
gene id: 580340:TLIE_RS09545
uniprot id: G7V932
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

580340:TLIE RS04280
gene id: 580340:TLIE_RS04280
uniprot id: G7V9L9
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

580340:TLIE RS04570
gene id: 580340:TLIE_RS04570
uniprot id: G7V9S2
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

580340:TLIE RS04075
gene id: 580340:TLIE_RS04075
uniprot id: G7V9H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

580340:TLIE RS09280
gene id: 580340:TLIE_RS09280
uniprot id: G7V8Y7
names: Subcellular Location Annotation
messages: Membrane

580340:TLIE RS06710
gene id: 580340:TLIE_RS06710
uniprot id: G7V637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

580340:TLIE RS02735
gene id: 580340:TLIE_RS02735
uniprot id: G7V8A7
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

580340:TLIE RS01475
gene id: 580340:TLIE_RS01475
uniprot id: G7V6S2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

580340:TLIE RS05800
gene id: 580340:TLIE_RS05800
uniprot id: G7V570
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

580340:TLIE RS08785
gene id: 580340:TLIE_RS08785
uniprot id: G7V893
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

580340:TLIE RS01810
gene id: 580340:TLIE_RS01810
uniprot id: G7V764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

580340:TLIE RS03825
gene id: 580340:TLIE_RS03825
uniprot id: G7V9B2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

580340:TLIE RS07955
gene id: 580340:TLIE_RS07955
uniprot id: G7V7E0
names: Similarity
messages: Belongs to the Fur family.

580340:TLIE RS04520
gene id: 580340:TLIE_RS04520
uniprot id: G7V9R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

580340:TLIE RS08630
gene id: 580340:TLIE_RS08630
uniprot id: G7V863
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

580340:TLIE RS05575
gene id: 580340:TLIE_RS05575
uniprot id: G7VAA9
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.