580332:SLIT RS05115
gene id: 580332:SLIT_RS05115
uniprot id: D5CQM6
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

580332:SLIT RS05375
gene id: 580332:SLIT_RS05375
uniprot id: D5CQS7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

580332:SLIT RS06045
gene id: 580332:SLIT_RS06045
uniprot id: D5CR65
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

580332:SLIT RS09895
gene id: 580332:SLIT_RS09895
uniprot id: D5CTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS03320
gene id: 580332:SLIT_RS03320
uniprot id: D5CNJ4
names: Similarity
messages: Belongs to the DEAD box helicase family.

580332:SLIT RS01990
gene id: 580332:SLIT_RS01990
uniprot id: D5CM27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

580332:SLIT RS07615
gene id: 580332:SLIT_RS07615
uniprot id: D5CS26
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

580332:SLIT RS06365
gene id: 580332:SLIT_RS06365
uniprot id: D5CRD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

580332:SLIT RS14790
gene id: 580332:SLIT_RS14790
uniprot id: D5CQG9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

580332:SLIT RS00045
gene id: 580332:SLIT_RS00045
uniprot id: D5CTE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

580332:SLIT RS12005
gene id: 580332:SLIT_RS12005
uniprot id: D5CMF5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

580332:SLIT RS04060
gene id: 580332:SLIT_RS04060
uniprot id: D5CPA9
names: Similarity
messages: Belongs to the NifZ family.

580332:SLIT RS13550
gene id: 580332:SLIT_RS13550
uniprot id: D5CP18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

580332:SLIT RS14330
gene id: 580332:SLIT_RS14330
uniprot id: D5CQ75
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

580332:SLIT RS10170
gene id: 580332:SLIT_RS10170
uniprot id: D5CTV1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580332:SLIT RS12230
gene id: 580332:SLIT_RS12230
uniprot id: D5CMJ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

580332:SLIT RS06195
gene id: 580332:SLIT_RS06195
uniprot id: D5CR95
names: Similarity
messages: Belongs to the BolA/IbaG family.

580332:SLIT RS07385
gene id: 580332:SLIT_RS07385
uniprot id: D5CRY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

580332:SLIT RS04990
gene id: 580332:SLIT_RS04990
uniprot id: D5CQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS01450
gene id: 580332:SLIT_RS01450
uniprot id: D5CLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

580332:SLIT RS12740
gene id: 580332:SLIT_RS12740
uniprot id: D5CN79
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

580332:SLIT RS10435
gene id: 580332:SLIT_RS10435
uniprot id: D5CU04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

580332:SLIT RS03965
gene id: 580332:SLIT_RS03965
uniprot id: D5CP90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

580332:SLIT RS10600
gene id: 580332:SLIT_RS10600
uniprot id: D5CUG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS05280
gene id: 580332:SLIT_RS05280
uniprot id: D5CQQ9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS09965
gene id: 580332:SLIT_RS09965
uniprot id: D5CTD6
names: Similarity
messages: Belongs to the PhoH family.

580332:SLIT RS12470
gene id: 580332:SLIT_RS12470
uniprot id: D5CMP8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

580332:SLIT RS07345
gene id: 580332:SLIT_RS07345
uniprot id: D5CRY0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

580332:SLIT RS12840
gene id: 580332:SLIT_RS12840
uniprot id: D5CN98
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

580332:SLIT RS13090
gene id: 580332:SLIT_RS13090
uniprot id: D5CNE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

580332:SLIT RS03865
gene id: 580332:SLIT_RS03865
uniprot id: D5CP70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

580332:SLIT RS12445
gene id: 580332:SLIT_RS12445
uniprot id: D5CMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

580332:SLIT RS05945
gene id: 580332:SLIT_RS05945
uniprot id: D5CR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580332:SLIT RS08655
gene id: 580332:SLIT_RS08655
uniprot id: D5CSM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

580332:SLIT RS05110
gene id: 580332:SLIT_RS05110
uniprot id: D5CQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

580332:SLIT RS07905
gene id: 580332:SLIT_RS07905
uniprot id: D5CS79
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS09275
gene id: 580332:SLIT_RS09275
uniprot id: D5CSZ6
names: Similarity
messages: Belongs to the Gfa family.

580332:SLIT RS07440
gene id: 580332:SLIT_RS07440
uniprot id: D5CRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

580332:SLIT RS04415
gene id: 580332:SLIT_RS04415
uniprot id: D5CPV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

580332:SLIT RS12915
gene id: 580332:SLIT_RS12915
uniprot id: D5CNB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS12265
gene id: 580332:SLIT_RS12265
uniprot id: D5CMK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

580332:SLIT RS03260
gene id: 580332:SLIT_RS03260
uniprot id: D5CNI2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

580332:SLIT RS00235
gene id: 580332:SLIT_RS00235
uniprot id: D5CTI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

580332:SLIT RS02540
gene id: 580332:SLIT_RS02540
uniprot id: D5CMR7
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS06980
gene id: 580332:SLIT_RS06980
uniprot id: D5CRQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

580332:SLIT RS08045
gene id: 580332:SLIT_RS08045
uniprot id: D5CSA5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

580332:SLIT RS00515
gene id: 580332:SLIT_RS00515
uniprot id: D5CTP0
names: Subcellular Location Annotation
messages: Cytoplasm

580332:SLIT RS05625
gene id: 580332:SLIT_RS05625
uniprot id: D5CQX6
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS02835
gene id: 580332:SLIT_RS02835
uniprot id: D5CMX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

580332:SLIT RS07530
gene id: 580332:SLIT_RS07530
uniprot id: D5CS12
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

580332:SLIT RS08680
gene id: 580332:SLIT_RS08680
uniprot id: D5CSN2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS12735
gene id: 580332:SLIT_RS12735
uniprot id: D5CN78
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

580332:SLIT RS11610
gene id: 580332:SLIT_RS11610
uniprot id: D5CLV5
names: Similarity
messages: Belongs to the AHA1 family.

580332:SLIT RS02720
gene id: 580332:SLIT_RS02720
uniprot id: D5CMV0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580332:SLIT RS10005
gene id: 580332:SLIT_RS10005
uniprot id: D5CTR8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS05285
gene id: 580332:SLIT_RS05285
uniprot id: D5CQR0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

580332:SLIT RS06760
gene id: 580332:SLIT_RS06760
uniprot id: D5CRK9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

580332:SLIT RS14505
gene id: 580332:SLIT_RS14505
uniprot id: D5CQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

580332:SLIT RS12115
gene id: 580332:SLIT_RS12115
uniprot id: D5CMH6
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

580332:SLIT RS00360
gene id: 580332:SLIT_RS00360
uniprot id: D5CTK7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

580332:SLIT RS07325
gene id: 580332:SLIT_RS07325
uniprot id: D5CRX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

580332:SLIT RS12435
gene id: 580332:SLIT_RS12435
uniprot id: D5CMP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

580332:SLIT RS13765
gene id: 580332:SLIT_RS13765
uniprot id: D5CPI6
names: Similarity
messages: Belongs to the YggT family.

580332:SLIT RS11750
gene id: 580332:SLIT_RS11750
uniprot id: D5CLY3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

580332:SLIT RS03870
gene id: 580332:SLIT_RS03870
uniprot id: D5CP71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

580332:SLIT RS04835
gene id: 580332:SLIT_RS04835
uniprot id: D5CQ42
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

580332:SLIT RS03830
gene id: 580332:SLIT_RS03830
uniprot id: D5CP51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

580332:SLIT RS02830
gene id: 580332:SLIT_RS02830
uniprot id: D5CMX2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

580332:SLIT RS08780
gene id: 580332:SLIT_RS08780
uniprot id: D5CSQ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

580332:SLIT RS04380
gene id: 580332:SLIT_RS04380
uniprot id: D5CPV0
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS02180
gene id: 580332:SLIT_RS02180
uniprot id: D5CM65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

580332:SLIT RS01980
gene id: 580332:SLIT_RS01980
uniprot id: D5CM25
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

580332:SLIT RS10285
gene id: 580332:SLIT_RS10285
uniprot id: D5CTX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

580332:SLIT RS15010
gene id: 580332:SLIT_RS15010
uniprot id: D5CLJ6
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS10565
gene id: 580332:SLIT_RS10565
uniprot id: D5CU30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

580332:SLIT RS03605
gene id: 580332:SLIT_RS03605
uniprot id: D5CNQ0
names: Similarity
messages: Belongs to the UPF0250 family.

580332:SLIT RS13750
gene id: 580332:SLIT_RS13750
uniprot id: D5CPI3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580332:SLIT RS13780
gene id: 580332:SLIT_RS13780
uniprot id: D5CPI9
names: Similarity
messages: Belongs to the GSP E family.

580332:SLIT RS07410
gene id: 580332:SLIT_RS07410
uniprot id: D5CRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

580332:SLIT RS03050
gene id: 580332:SLIT_RS03050
uniprot id: D5CN17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

580332:SLIT RS02585
gene id: 580332:SLIT_RS02585
uniprot id: D5CMS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

580332:SLIT RS13665
gene id: 580332:SLIT_RS13665
uniprot id: D5CP40
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

580332:SLIT RS08720
gene id: 580332:SLIT_RS08720
uniprot id: D5CSN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

580332:SLIT RS00200
gene id: 580332:SLIT_RS00200
uniprot id: D5CTH4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

580332:SLIT RS03330
gene id: 580332:SLIT_RS03330
uniprot id: D5CNJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

580332:SLIT RS00905
gene id: 580332:SLIT_RS00905
uniprot id: D5CU88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

580332:SLIT RS12290
gene id: 580332:SLIT_RS12290
uniprot id: D5CML0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

580332:SLIT RS14610
gene id: 580332:SLIT_RS14610
uniprot id: D5CQD2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

580332:SLIT RS14855
gene id: 580332:SLIT_RS14855
uniprot id: D5CQI2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS08270
gene id: 580332:SLIT_RS08270
uniprot id: D5CSF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS05210
gene id: 580332:SLIT_RS05210
uniprot id: D5CQP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

580332:SLIT RS08795
gene id: 580332:SLIT_RS08795
uniprot id: D5CSQ5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

580332:SLIT RS01420
gene id: 580332:SLIT_RS01420
uniprot id: D5CLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

580332:SLIT RS08185
gene id: 580332:SLIT_RS08185
uniprot id: D5CSD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

580332:SLIT RS03400
gene id: 580332:SLIT_RS03400
uniprot id: D5CNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

580332:SLIT RS05415
gene id: 580332:SLIT_RS05415
uniprot id: D5CQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS14440
gene id: 580332:SLIT_RS14440
uniprot id: D5CQ97
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

580332:SLIT RS04540
gene id: 580332:SLIT_RS04540
uniprot id: D5CPY3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

580332:SLIT RS04810
gene id: 580332:SLIT_RS04810
uniprot id: D5CQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS06250
gene id: 580332:SLIT_RS06250
uniprot id: D5CRA6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580332:SLIT RS13870
gene id: 580332:SLIT_RS13870
uniprot id: D5CPK7
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS05835
gene id: 580332:SLIT_RS05835
uniprot id: D5CR24
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

580332:SLIT RS10540
gene id: 580332:SLIT_RS10540
uniprot id: D5CU25
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS13080
gene id: 580332:SLIT_RS13080
uniprot id: D5CNE6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS10150
gene id: 580332:SLIT_RS10150
uniprot id: D5CTU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

580332:SLIT RS02490
gene id: 580332:SLIT_RS02490
uniprot id: D5CMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS07625
gene id: 580332:SLIT_RS07625
uniprot id: D5CS28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

580332:SLIT RS10530
gene id: 580332:SLIT_RS10530
uniprot id: D5CU23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

580332:SLIT RS14220
gene id: 580332:SLIT_RS14220
uniprot id: D5CPS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

580332:SLIT RS14620
gene id: 580332:SLIT_RS14620
uniprot id: D5CQD4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

580332:SLIT RS04155
gene id: 580332:SLIT_RS04155
uniprot id: D5CPC9
names: Similarity
messages: Belongs to the peptidase S24 family.

580332:SLIT RS12045
gene id: 580332:SLIT_RS12045
uniprot id: D5CMG3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS11255
gene id: 580332:SLIT_RS11255
uniprot id: D5CLN7
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

580332:SLIT RS05295
gene id: 580332:SLIT_RS05295
uniprot id: D5CQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

580332:SLIT RS00585
gene id: 580332:SLIT_RS00585
uniprot id: D5CTQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

580332:SLIT RS09865
gene id: 580332:SLIT_RS09865
uniprot id: D5CTB7
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS11925
gene id: 580332:SLIT_RS11925
uniprot id: D5CMD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

580332:SLIT RS01550
gene id: 580332:SLIT_RS01550
uniprot id: D5CLH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

580332:SLIT RS07775
gene id: 580332:SLIT_RS07775
uniprot id: D5CS54
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

580332:SLIT RS13515
gene id: 580332:SLIT_RS13515
uniprot id: D5CP10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

580332:SLIT RS14895
gene id: 580332:SLIT_RS14895
uniprot id: D5CQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

580332:SLIT RS02030
gene id: 580332:SLIT_RS02030
uniprot id: D5CM35
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

580332:SLIT RS01225
gene id: 580332:SLIT_RS01225
uniprot id: D5CLA4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

580332:SLIT RS02625
gene id: 580332:SLIT_RS02625
uniprot id: D5CMT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

580332:SLIT RS08965
gene id: 580332:SLIT_RS08965
uniprot id: D5CST7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

580332:SLIT RS09295
gene id: 580332:SLIT_RS09295
uniprot id: D5CT00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

580332:SLIT RS14570
gene id: 580332:SLIT_RS14570
uniprot id: D5CQC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS10450
gene id: 580332:SLIT_RS10450
uniprot id: D5CU07
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

580332:SLIT RS14460
gene id: 580332:SLIT_RS14460
uniprot id: D5CQA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

580332:SLIT RS13585
gene id: 580332:SLIT_RS13585
uniprot id: D5CP25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

580332:SLIT RS12800
gene id: 580332:SLIT_RS12800
uniprot id: D5CN91
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS15040
gene id: 580332:SLIT_RS15040
uniprot id: D5CMU2
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

580332:SLIT RS07160
gene id: 580332:SLIT_RS07160
uniprot id: D5CRU2
names: Similarity
messages: Belongs to the GSP E family.

580332:SLIT RS03255
gene id: 580332:SLIT_RS03255
uniprot id: D5CNI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

580332:SLIT RS13570
gene id: 580332:SLIT_RS13570
uniprot id: D5CP22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

580332:SLIT RS14280
gene id: 580332:SLIT_RS14280
uniprot id: D5CPU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

580332:SLIT RS04290
gene id: 580332:SLIT_RS04290
uniprot id: D5CPF3
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

580332:SLIT RS02810
gene id: 580332:SLIT_RS02810
uniprot id: D5CMW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

580332:SLIT RS11960
gene id: 580332:SLIT_RS11960
uniprot id: D5CME6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS13775
gene id: 580332:SLIT_RS13775
uniprot id: D5CPI8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

580332:SLIT RS04520
gene id: 580332:SLIT_RS04520
uniprot id: D5CPX9
names: Similarity
messages: Belongs to the NifX/NifY family.

580332:SLIT RS10655
gene id: 580332:SLIT_RS10655
uniprot id: D5CUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

580332:SLIT RS13055
gene id: 580332:SLIT_RS13055
uniprot id: D5CNE1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

580332:SLIT RS07275
gene id: 580332:SLIT_RS07275
uniprot id: D5CRW6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

580332:SLIT RS09345
gene id: 580332:SLIT_RS09345
uniprot id: D5CT10
names: Similarity
messages: Belongs to the CFA/CMAS family.

580332:SLIT RS05030
gene id: 580332:SLIT_RS05030
uniprot id: D5CQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

580332:SLIT RS05360
gene id: 580332:SLIT_RS05360
uniprot id: D5CQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS01620
gene id: 580332:SLIT_RS01620
uniprot id: D5CLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

580332:SLIT RS05320
gene id: 580332:SLIT_RS05320
uniprot id: D5CQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS00195
gene id: 580332:SLIT_RS00195
uniprot id: D5CTH3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

580332:SLIT RS06775
gene id: 580332:SLIT_RS06775
uniprot id: D5CRL2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580332:SLIT RS02970
gene id: 580332:SLIT_RS02970
uniprot id: D5CN00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

580332:SLIT RS09215
gene id: 580332:SLIT_RS09215
uniprot id: D5CSY4
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

580332:SLIT RS04635
gene id: 580332:SLIT_RS04635
uniprot id: D5CQ03
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

580332:SLIT RS08210
gene id: 580332:SLIT_RS08210
uniprot id: D5CSD9
names: Similarity
messages: Belongs to the skp family.

580332:SLIT RS08525
gene id: 580332:SLIT_RS08525
uniprot id: D5CSK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

580332:SLIT RS05370
gene id: 580332:SLIT_RS05370
uniprot id: D5CQS6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

580332:SLIT RS13895
gene id: 580332:SLIT_RS13895
uniprot id: D5CPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

580332:SLIT RS14635
gene id: 580332:SLIT_RS14635
uniprot id: D5CQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

580332:SLIT RS13760
gene id: 580332:SLIT_RS13760
uniprot id: D5CPI5
names: Similarity
messages: Belongs to the UPF0235 family.

580332:SLIT RS14275
gene id: 580332:SLIT_RS14275
uniprot id: D5CPU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

580332:SLIT RS07065
gene id: 580332:SLIT_RS07065
uniprot id: D5CRS4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

580332:SLIT RS11200
gene id: 580332:SLIT_RS11200
uniprot id: D5CLM6
names: Similarity
messages: Belongs to the DEAD box helicase family.

580332:SLIT RS01630
gene id: 580332:SLIT_RS01630
uniprot id: D5CLI5
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

580332:SLIT RS03360
gene id: 580332:SLIT_RS03360
uniprot id: D5CNK2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

580332:SLIT RS07280
gene id: 580332:SLIT_RS07280
uniprot id: D5CRW7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

580332:SLIT RS14535
gene id: 580332:SLIT_RS14535
uniprot id: D5CQB7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

580332:SLIT RS09300
gene id: 580332:SLIT_RS09300
uniprot id: D5CT01
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

580332:SLIT RS05105
gene id: 580332:SLIT_RS05105
uniprot id: D5CQM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

580332:SLIT RS14670
gene id: 580332:SLIT_RS14670
uniprot id: D5CQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

580332:SLIT RS05960
gene id: 580332:SLIT_RS05960
uniprot id: D5CR48
names: Similarity
messages: Belongs to the peptidase S16 family.

580332:SLIT RS10585
gene id: 580332:SLIT_RS10585
uniprot id: D5CUF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS05055
gene id: 580332:SLIT_RS05055
uniprot id: D5CQL4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS09410
gene id: 580332:SLIT_RS09410
uniprot id: D5CT24
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

580332:SLIT RS08405
gene id: 580332:SLIT_RS08405
uniprot id: D5CSH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

580332:SLIT RS01480
gene id: 580332:SLIT_RS01480
uniprot id: D5CLF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

580332:SLIT RS07570
gene id: 580332:SLIT_RS07570
uniprot id: D5CS20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

580332:SLIT RS02530
gene id: 580332:SLIT_RS02530
uniprot id: D5CMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

580332:SLIT RS14925
gene id: 580332:SLIT_RS14925
uniprot id: D5CQJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

580332:SLIT RS06400
gene id: 580332:SLIT_RS06400
uniprot id: D5CRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

580332:SLIT RS00305
gene id: 580332:SLIT_RS00305
uniprot id: D5CTJ6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

580332:SLIT RS05305
gene id: 580332:SLIT_RS05305
uniprot id: D5CQR4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

580332:SLIT RS07165
gene id: 580332:SLIT_RS07165
uniprot id: D5CRU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

580332:SLIT RS09945
gene id: 580332:SLIT_RS09945
uniprot id: D5CTD2
names: Similarity
messages: Belongs to the YkuD family.

580332:SLIT RS02350
gene id: 580332:SLIT_RS02350
uniprot id: D5CMA0
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

580332:SLIT RS06215
gene id: 580332:SLIT_RS06215
uniprot id: D5CR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

580332:SLIT RS00780
gene id: 580332:SLIT_RS00780
uniprot id: D5CU63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580332:SLIT RS11470
gene id: 580332:SLIT_RS11470
uniprot id: D5CLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

580332:SLIT RS00315
gene id: 580332:SLIT_RS00315
uniprot id: D5CTJ8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

580332:SLIT RS15220
gene id: 580332:SLIT_RS15220
uniprot id: D5CSI7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

580332:SLIT RS06285
gene id: 580332:SLIT_RS06285
uniprot id: D5CRB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

580332:SLIT RS04800
gene id: 580332:SLIT_RS04800
uniprot id: D5CQ35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

580332:SLIT RS00065
gene id: 580332:SLIT_RS00065
uniprot id: D5CTE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

580332:SLIT RS12490
gene id: 580332:SLIT_RS12490
uniprot id: D5CN27
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

580332:SLIT RS06635
gene id: 580332:SLIT_RS06635
uniprot id: D5CRI3
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS02430
gene id: 580332:SLIT_RS02430
uniprot id: D5CMB5
names: Similarity
messages: Belongs to the GSP N family.

580332:SLIT RS12365
gene id: 580332:SLIT_RS12365
uniprot id: D5CMM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

580332:SLIT RS14685
gene id: 580332:SLIT_RS14685
uniprot id: D5CQE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

580332:SLIT RS04000
gene id: 580332:SLIT_RS04000
uniprot id: D5CP97
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS06530
gene id: 580332:SLIT_RS06530
uniprot id: D5CRG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

580332:SLIT RS03850
gene id: 580332:SLIT_RS03850
uniprot id: D5CP67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

580332:SLIT RS12520
gene id: 580332:SLIT_RS12520
uniprot id: D5CN33
names: Similarity
messages: Belongs to the TrpC family.

580332:SLIT RS13375
gene id: 580332:SLIT_RS13375
uniprot id: D5CNY3
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS09105
gene id: 580332:SLIT_RS09105
uniprot id: D5CSW3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

580332:SLIT RS13675
gene id: 580332:SLIT_RS13675
uniprot id: D5CP42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

580332:SLIT RS14380
gene id: 580332:SLIT_RS14380
uniprot id: D5CQ85
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS03120
gene id: 580332:SLIT_RS03120
uniprot id: D5CNF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

580332:SLIT RS11310
gene id: 580332:SLIT_RS11310
uniprot id: D5CLP8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

580332:SLIT RS09910
gene id: 580332:SLIT_RS09910
uniprot id: D5CTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS06965
gene id: 580332:SLIT_RS06965
uniprot id: D5CRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

580332:SLIT RS11295
gene id: 580332:SLIT_RS11295
uniprot id: D5CLP5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

580332:SLIT RS09375
gene id: 580332:SLIT_RS09375
uniprot id: D5CT16
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

580332:SLIT RS14630
gene id: 580332:SLIT_RS14630
uniprot id: D5CQD6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

580332:SLIT RS02795
gene id: 580332:SLIT_RS02795
uniprot id: D5CMW5
names: Similarity
messages: Belongs to the MotB family.

580332:SLIT RS03695
gene id: 580332:SLIT_RS03695
uniprot id: D5CNR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS10360
gene id: 580332:SLIT_RS10360
uniprot id: D5CTZ0
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

580332:SLIT RS06655
gene id: 580332:SLIT_RS06655
uniprot id: D5CRI7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

580332:SLIT RS12530
gene id: 580332:SLIT_RS12530
uniprot id: D5CN35
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

580332:SLIT RS05730
gene id: 580332:SLIT_RS05730
uniprot id: D5CR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

580332:SLIT RS03240
gene id: 580332:SLIT_RS03240
uniprot id: D5CNH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

580332:SLIT RS03930
gene id: 580332:SLIT_RS03930
uniprot id: D5CP83
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

580332:SLIT RS03465
gene id: 580332:SLIT_RS03465
uniprot id: D5CNM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

580332:SLIT RS10625
gene id: 580332:SLIT_RS10625
uniprot id: D5CUG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

580332:SLIT RS09205
gene id: 580332:SLIT_RS09205
uniprot id: D5CSY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS08200
gene id: 580332:SLIT_RS08200
uniprot id: D5CSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

580332:SLIT RS00835
gene id: 580332:SLIT_RS00835
uniprot id: D5CU74
names: Subcellular Location Annotation
messages: Mitochondrion

580332:SLIT RS07645
gene id: 580332:SLIT_RS07645
uniprot id: D5CS32
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

580332:SLIT RS12885
gene id: 580332:SLIT_RS12885
uniprot id: D5CNA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

580332:SLIT RS08855
gene id: 580332:SLIT_RS08855
uniprot id: D5CSR7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

580332:SLIT RS10330
gene id: 580332:SLIT_RS10330
uniprot id: D5CTY4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

580332:SLIT RS00095
gene id: 580332:SLIT_RS00095
uniprot id: D5CTF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

580332:SLIT RS07975
gene id: 580332:SLIT_RS07975
uniprot id: D5CS93
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS09330
gene id: 580332:SLIT_RS09330
uniprot id: D5CT07
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS05145
gene id: 580332:SLIT_RS05145
uniprot id: D5CQN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

580332:SLIT RS03895
gene id: 580332:SLIT_RS03895
uniprot id: D5CP76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

580332:SLIT RS03435
gene id: 580332:SLIT_RS03435
uniprot id: D5CNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS04315
gene id: 580332:SLIT_RS04315
uniprot id: D5CPF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS14100
gene id: 580332:SLIT_RS14100
uniprot id: D5CPQ3
names: Similarity
messages: Belongs to the UPF0235 family.

580332:SLIT RS08315
gene id: 580332:SLIT_RS08315
uniprot id: D5CSG0
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

580332:SLIT RS00160
gene id: 580332:SLIT_RS00160
uniprot id: D5CTG7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

580332:SLIT RS02395
gene id: 580332:SLIT_RS02395
uniprot id: D5CMA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS13480
gene id: 580332:SLIT_RS13480
uniprot id: D5CP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

580332:SLIT RS04140
gene id: 580332:SLIT_RS04140
uniprot id: D5CPC6
names: Similarity
messages: Belongs to the pirin family.

580332:SLIT RS13620
gene id: 580332:SLIT_RS13620
uniprot id: D5CP32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

580332:SLIT RS13825
gene id: 580332:SLIT_RS13825
uniprot id: D5CPJ8
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS07025
gene id: 580332:SLIT_RS07025
uniprot id: D5CRR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

580332:SLIT RS14530
gene id: 580332:SLIT_RS14530
uniprot id: D5CQB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

580332:SLIT RS14920
gene id: 580332:SLIT_RS14920
uniprot id: D5CQJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

580332:SLIT RS11920
gene id: 580332:SLIT_RS11920
uniprot id: D5CMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

580332:SLIT RS01525
gene id: 580332:SLIT_RS01525
uniprot id: D5CLG5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

580332:SLIT RS02850
gene id: 580332:SLIT_RS02850
uniprot id: D5CMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

580332:SLIT RS14865
gene id: 580332:SLIT_RS14865
uniprot id: D5CQI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

580332:SLIT RS03150
gene id: 580332:SLIT_RS03150
uniprot id: D5CNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

580332:SLIT RS06350
gene id: 580332:SLIT_RS06350
uniprot id: D5CRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

580332:SLIT RS03815
gene id: 580332:SLIT_RS03815
uniprot id: D5CP60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

580332:SLIT RS14250
gene id: 580332:SLIT_RS14250
uniprot id: D5CPT4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

580332:SLIT RS11240
gene id: 580332:SLIT_RS11240
uniprot id: D5CLN4
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

580332:SLIT RS04830
gene id: 580332:SLIT_RS04830
uniprot id: D5CQ41
names: Subcellular Location Annotation
messages: Cytoplasm

580332:SLIT RS12765
gene id: 580332:SLIT_RS12765
uniprot id: D5CN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

580332:SLIT RS11290
gene id: 580332:SLIT_RS11290
uniprot id: D5CLP4
names: Similarity
messages: Belongs to the UPF0111 family.

580332:SLIT RS05025
gene id: 580332:SLIT_RS05025
uniprot id: D5CQK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03880
gene id: 580332:SLIT_RS03880
uniprot id: D5CP73
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

580332:SLIT RS12285
gene id: 580332:SLIT_RS12285
uniprot id: D5CMK9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

580332:SLIT RS05135
gene id: 580332:SLIT_RS05135
uniprot id: D5CQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

580332:SLIT RS03510
gene id: 580332:SLIT_RS03510
uniprot id: D5CNN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

580332:SLIT RS04300
gene id: 580332:SLIT_RS04300
uniprot id: D5CPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS10875
gene id: 580332:SLIT_RS10875
uniprot id: D5CUL5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

580332:SLIT RS03720
gene id: 580332:SLIT_RS03720
uniprot id: D5CNS3
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

580332:SLIT RS08975
gene id: 580332:SLIT_RS08975
uniprot id: D5CST9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

580332:SLIT RS05380
gene id: 580332:SLIT_RS05380
uniprot id: D5CQS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS15375
gene id: 580332:SLIT_RS15375
uniprot id: D5CMI0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580332:SLIT RS11970
gene id: 580332:SLIT_RS11970
uniprot id: D5CME8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS11985
gene id: 580332:SLIT_RS11985
uniprot id: D5CMF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

580332:SLIT RS05710
gene id: 580332:SLIT_RS05710
uniprot id: D5CQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

580332:SLIT RS04825
gene id: 580332:SLIT_RS04825
uniprot id: D5CQ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

580332:SLIT RS09035
gene id: 580332:SLIT_RS09035
uniprot id: D5CSU9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

580332:SLIT RS07605
gene id: 580332:SLIT_RS07605
uniprot id: D5CS24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

580332:SLIT RS06060
gene id: 580332:SLIT_RS06060
uniprot id: D5CR68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

580332:SLIT RS13605
gene id: 580332:SLIT_RS13605
uniprot id: D5CP29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

580332:SLIT RS06700
gene id: 580332:SLIT_RS06700
uniprot id: D5CRJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

580332:SLIT RS07210
gene id: 580332:SLIT_RS07210
uniprot id: D5CRV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

580332:SLIT RS00930
gene id: 580332:SLIT_RS00930
uniprot id: D5CU93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

580332:SLIT RS07480
gene id: 580332:SLIT_RS07480
uniprot id: D5CS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

580332:SLIT RS09425
gene id: 580332:SLIT_RS09425
uniprot id: D5CT27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

580332:SLIT RS12050
gene id: 580332:SLIT_RS12050
uniprot id: D5CMG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

580332:SLIT RS01965
gene id: 580332:SLIT_RS01965
uniprot id: D5CM22
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS00120
gene id: 580332:SLIT_RS00120
uniprot id: D5CTF9
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

580332:SLIT RS00320
gene id: 580332:SLIT_RS00320
uniprot id: D5CTJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

580332:SLIT RS02380
gene id: 580332:SLIT_RS02380
uniprot id: D5CMA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

580332:SLIT RS13795
gene id: 580332:SLIT_RS13795
uniprot id: D5CPJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

580332:SLIT RS14585
gene id: 580332:SLIT_RS14585
uniprot id: D5CQC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

580332:SLIT RS11125
gene id: 580332:SLIT_RS11125
uniprot id: D5CUR8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

580332:SLIT RS02935
gene id: 580332:SLIT_RS02935
uniprot id: D5CMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

580332:SLIT RS11005
gene id: 580332:SLIT_RS11005
uniprot id: D5CUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

580332:SLIT RS09030
gene id: 580332:SLIT_RS09030
uniprot id: D5CSU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

580332:SLIT RS14375
gene id: 580332:SLIT_RS14375
uniprot id: D5CQ84
names: Similarity
messages: Belongs to the polysaccharide synthase family.

580332:SLIT RS14060
gene id: 580332:SLIT_RS14060
uniprot id: D5CPP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

580332:SLIT RS06995
gene id: 580332:SLIT_RS06995
uniprot id: D5CRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

580332:SLIT RS12770
gene id: 580332:SLIT_RS12770
uniprot id: D5CN85
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

580332:SLIT RS08275
gene id: 580332:SLIT_RS08275
uniprot id: D5CSF2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

580332:SLIT RS12820
gene id: 580332:SLIT_RS12820
uniprot id: D5CN95
names: Subcellular Location Annotation
messages: Cytoplasm

580332:SLIT RS12440
gene id: 580332:SLIT_RS12440
uniprot id: D5CMP2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

580332:SLIT RS14775
gene id: 580332:SLIT_RS14775
uniprot id: D5CQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

580332:SLIT RS07240
gene id: 580332:SLIT_RS07240
uniprot id: D5CRV9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

580332:SLIT RS00530
gene id: 580332:SLIT_RS00530
uniprot id: D5CTP3
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

580332:SLIT RS14480
gene id: 580332:SLIT_RS14480
uniprot id: D5CQA5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS04730
gene id: 580332:SLIT_RS04730
uniprot id: D5CQ22
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

580332:SLIT RS06210
gene id: 580332:SLIT_RS06210
uniprot id: D5CR98
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS09430
gene id: 580332:SLIT_RS09430
uniprot id: D5CT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

580332:SLIT RS12410
gene id: 580332:SLIT_RS12410
uniprot id: D5CMN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS02805
gene id: 580332:SLIT_RS02805
uniprot id: D5CMW7
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

580332:SLIT RS04725
gene id: 580332:SLIT_RS04725
uniprot id: D5CQ21
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

580332:SLIT RS02895
gene id: 580332:SLIT_RS02895
uniprot id: D5CMY5
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

580332:SLIT RS05330
gene id: 580332:SLIT_RS05330
uniprot id: D5CQR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

580332:SLIT RS07415
gene id: 580332:SLIT_RS07415
uniprot id: D5CRZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

580332:SLIT RS00565
gene id: 580332:SLIT_RS00565
uniprot id: D5CTQ0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

580332:SLIT RS08540
gene id: 580332:SLIT_RS08540
uniprot id: D5CSK4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

580332:SLIT RS06340
gene id: 580332:SLIT_RS06340
uniprot id: D5CRC5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

580332:SLIT RS06975
gene id: 580332:SLIT_RS06975
uniprot id: D5CRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

580332:SLIT RS06385
gene id: 580332:SLIT_RS06385
uniprot id: D5CRD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

580332:SLIT RS13770
gene id: 580332:SLIT_RS13770
uniprot id: D5CPI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

580332:SLIT RS09130
gene id: 580332:SLIT_RS09130
uniprot id: D5CSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

580332:SLIT RS12460
gene id: 580332:SLIT_RS12460
uniprot id: D5CMP6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS05770
gene id: 580332:SLIT_RS05770
uniprot id: D5CR10
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580332:SLIT RS01305
gene id: 580332:SLIT_RS01305
uniprot id: D5CLC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

580332:SLIT RS02150
gene id: 580332:SLIT_RS02150
uniprot id: D5CM59
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

580332:SLIT RS12620
gene id: 580332:SLIT_RS12620
uniprot id: D5CN54
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS03910
gene id: 580332:SLIT_RS03910
uniprot id: D5CP79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

580332:SLIT RS08415
gene id: 580332:SLIT_RS08415
uniprot id: D5CSI0
names: Similarity
messages: Belongs to the DsrF/TusC family.

580332:SLIT RS07635
gene id: 580332:SLIT_RS07635
uniprot id: D5CS30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

580332:SLIT RS11440
gene id: 580332:SLIT_RS11440
uniprot id: D5CLS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

580332:SLIT RS04185
gene id: 580332:SLIT_RS04185
uniprot id: D5CPD5
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

580332:SLIT RS06795
gene id: 580332:SLIT_RS06795
uniprot id: D5CRL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

580332:SLIT RS02670
gene id: 580332:SLIT_RS02670
uniprot id: D5CMU0
names: Similarity
messages: Belongs to the GSP E family.

580332:SLIT RS12685
gene id: 580332:SLIT_RS12685
uniprot id: D5CN68
names: Similarity
messages: Belongs to the HSP15 family.

580332:SLIT RS03935
gene id: 580332:SLIT_RS03935
uniprot id: D5CP84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

580332:SLIT RS03840
gene id: 580332:SLIT_RS03840
uniprot id: D5CP65
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

580332:SLIT RS04475
gene id: 580332:SLIT_RS04475
uniprot id: D5CPX0
names: Similarity
messages: Belongs to the ModE family.

580332:SLIT RS12930
gene id: 580332:SLIT_RS12930
uniprot id: D5CNB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

580332:SLIT RS00665
gene id: 580332:SLIT_RS00665
uniprot id: D5CU41
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

580332:SLIT RS13465
gene id: 580332:SLIT_RS13465
uniprot id: D5CP00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS06790
gene id: 580332:SLIT_RS06790
uniprot id: D5CRL5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

580332:SLIT RS13500
gene id: 580332:SLIT_RS13500
uniprot id: D5CP07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

580332:SLIT RS01160
gene id: 580332:SLIT_RS01160
uniprot id: D5CUE2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

580332:SLIT RS00500
gene id: 580332:SLIT_RS00500
uniprot id: D5CTN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

580332:SLIT RS00580
gene id: 580332:SLIT_RS00580
uniprot id: D5CTQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS00675
gene id: 580332:SLIT_RS00675
uniprot id: D5CU43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

580332:SLIT RS02950
gene id: 580332:SLIT_RS02950
uniprot id: D5CMZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

580332:SLIT RS05245
gene id: 580332:SLIT_RS05245
uniprot id: D5CQQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

580332:SLIT RS04555
gene id: 580332:SLIT_RS04555
uniprot id: D5CPY6
names: Similarity
messages: Belongs to the NifZ family.

580332:SLIT RS13725
gene id: 580332:SLIT_RS13725
uniprot id: D5CPH8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

580332:SLIT RS00810
gene id: 580332:SLIT_RS00810
uniprot id: D5CU69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

580332:SLIT RS13320
gene id: 580332:SLIT_RS13320
uniprot id: D5CNX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

580332:SLIT RS12935
gene id: 580332:SLIT_RS12935
uniprot id: D5CNB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

580332:SLIT RS09985
gene id: 580332:SLIT_RS09985
uniprot id: D5CTR4
names: Similarity
messages: Belongs to the YciI family.

580332:SLIT RS02815
gene id: 580332:SLIT_RS02815
uniprot id: D5CMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

580332:SLIT RS14270
gene id: 580332:SLIT_RS14270
uniprot id: D5CPT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

580332:SLIT RS12415
gene id: 580332:SLIT_RS12415
uniprot id: D5CMN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS10320
gene id: 580332:SLIT_RS10320
uniprot id: D5CTY2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

580332:SLIT RS13035
gene id: 580332:SLIT_RS13035
uniprot id: D5CND7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

580332:SLIT RS12645
gene id: 580332:SLIT_RS12645
uniprot id: D5CN59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS05335
gene id: 580332:SLIT_RS05335
uniprot id: D5CQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

580332:SLIT RS09860
gene id: 580332:SLIT_RS09860
uniprot id: D5CTB6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

580332:SLIT RS13030
gene id: 580332:SLIT_RS13030
uniprot id: D5CND6
names: Similarity
messages: Belongs to the GSP E family.

580332:SLIT RS03825
gene id: 580332:SLIT_RS03825
uniprot id: D5CP62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

580332:SLIT RS13025
gene id: 580332:SLIT_RS13025
uniprot id: D5CND5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

580332:SLIT RS00015
gene id: 580332:SLIT_RS00015
uniprot id: D5CTD9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

580332:SLIT RS10135
gene id: 580332:SLIT_RS10135
uniprot id: D5CTU4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

580332:SLIT RS09830
gene id: 580332:SLIT_RS09830
uniprot id: D5CTA8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS13100
gene id: 580332:SLIT_RS13100
uniprot id: D5CNS6
names: Similarity
messages: Belongs to the peptidase S41A family.

580332:SLIT RS10145
gene id: 580332:SLIT_RS10145
uniprot id: D5CTU6
names: Similarity
messages: Belongs to the UPF0166 family.

580332:SLIT RS03715
gene id: 580332:SLIT_RS03715
uniprot id: D5CNS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS06960
gene id: 580332:SLIT_RS06960
uniprot id: D5CRQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

580332:SLIT RS06430
gene id: 580332:SLIT_RS06430
uniprot id: D5CRE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03350
gene id: 580332:SLIT_RS03350
uniprot id: D5CNK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580332:SLIT RS11145
gene id: 580332:SLIT_RS11145
uniprot id: D5CUS2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

580332:SLIT RS14320
gene id: 580332:SLIT_RS14320
uniprot id: D5CPU9
names: Subcellular Location Annotation
messages: Cytoplasm

580332:SLIT RS01685
gene id: 580332:SLIT_RS01685
uniprot id: D5CLJ7
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS05220
gene id: 580332:SLIT_RS05220
uniprot id: D5CQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

580332:SLIT RS00470
gene id: 580332:SLIT_RS00470
uniprot id: D5CTN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcriptional regulator.

580332:SLIT RS06510
gene id: 580332:SLIT_RS06510
uniprot id: D5CRF8
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS09070
gene id: 580332:SLIT_RS09070
uniprot id: D5CSV6
names: Similarity
messages: Belongs to the SCO1/2 family.

580332:SLIT RS06870
gene id: 580332:SLIT_RS06870
uniprot id: D5CRN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580332:SLIT RS05400
gene id: 580332:SLIT_RS05400
uniprot id: D5CQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS15195
gene id: 580332:SLIT_RS15195
uniprot id: D5CS52
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS03590
gene id: 580332:SLIT_RS03590
uniprot id: D5CNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS12605
gene id: 580332:SLIT_RS12605
uniprot id: D5CN51
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

580332:SLIT RS09010
gene id: 580332:SLIT_RS09010
uniprot id: D5CSU4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580332:SLIT RS00035
gene id: 580332:SLIT_RS00035
uniprot id: D5CTE2
names: Similarity
messages: Belongs to the DprA/Smf family.

580332:SLIT RS05150
gene id: 580332:SLIT_RS05150
uniprot id: D5CQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS09435
gene id: 580332:SLIT_RS09435
uniprot id: D5CT29
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS02155
gene id: 580332:SLIT_RS02155
uniprot id: D5CM60
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

580332:SLIT RS03860
gene id: 580332:SLIT_RS03860
uniprot id: D5CP69
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

580332:SLIT RS01985
gene id: 580332:SLIT_RS01985
uniprot id: D5CM26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

580332:SLIT RS03505
gene id: 580332:SLIT_RS03505
uniprot id: D5CNN1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

580332:SLIT RS02010
gene id: 580332:SLIT_RS02010
uniprot id: D5CM31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

580332:SLIT RS11270
gene id: 580332:SLIT_RS11270
uniprot id: D5CLP0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

580332:SLIT RS11955
gene id: 580332:SLIT_RS11955
uniprot id: D5CME5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS13475
gene id: 580332:SLIT_RS13475
uniprot id: D5CP02
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS02335
gene id: 580332:SLIT_RS02335
uniprot id: D5CM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

580332:SLIT RS12755
gene id: 580332:SLIT_RS12755
uniprot id: D5CN82
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

580332:SLIT RS12550
gene id: 580332:SLIT_RS12550
uniprot id: D5CN39
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS11845
gene id: 580332:SLIT_RS11845
uniprot id: D5CMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

580332:SLIT RS07145
gene id: 580332:SLIT_RS07145
uniprot id: D5CRT9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

580332:SLIT RS09370
gene id: 580332:SLIT_RS09370
uniprot id: D5CT15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

580332:SLIT RS04980
gene id: 580332:SLIT_RS04980
uniprot id: D5CQ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS04765
gene id: 580332:SLIT_RS04765
uniprot id: D5CQ29
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

580332:SLIT RS01500
gene id: 580332:SLIT_RS01500
uniprot id: D5CLF9
names: Similarity
messages: Belongs to the Dps family.

580332:SLIT RS04900
gene id: 580332:SLIT_RS04900
uniprot id: D5CQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

580332:SLIT RS07125
gene id: 580332:SLIT_RS07125
uniprot id: D5CRT5
names: Similarity
messages: Belongs to the MipA/OmpV family.

580332:SLIT RS07060
gene id: 580332:SLIT_RS07060
uniprot id: D5CRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

580332:SLIT RS07910
gene id: 580332:SLIT_RS07910
uniprot id: D5CS80
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

580332:SLIT RS00005
gene id: 580332:SLIT_RS00005
uniprot id: D5CTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

580332:SLIT RS03905
gene id: 580332:SLIT_RS03905
uniprot id: D5CP78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

580332:SLIT RS08155
gene id: 580332:SLIT_RS08155
uniprot id: D5CSC8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

580332:SLIT RS14215
gene id: 580332:SLIT_RS14215
uniprot id: D5CPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

580332:SLIT RS00140
gene id: 580332:SLIT_RS00140
uniprot id: D5CTG3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

580332:SLIT RS05620
gene id: 580332:SLIT_RS05620
uniprot id: D5CQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS07455
gene id: 580332:SLIT_RS07455
uniprot id: D5CS00
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS14910
gene id: 580332:SLIT_RS14910
uniprot id: D5CQJ3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

580332:SLIT RS04360
gene id: 580332:SLIT_RS04360
uniprot id: D5CPG8
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS01265
gene id: 580332:SLIT_RS01265
uniprot id: D5CLB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

580332:SLIT RS12870
gene id: 580332:SLIT_RS12870
uniprot id: D5CNA4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS07670
gene id: 580332:SLIT_RS07670
uniprot id: D5CS37
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

580332:SLIT RS02945
gene id: 580332:SLIT_RS02945
uniprot id: D5CMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

580332:SLIT RS13820
gene id: 580332:SLIT_RS13820
uniprot id: D5CPJ7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

580332:SLIT RS00135
gene id: 580332:SLIT_RS00135
uniprot id: D5CTG2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

580332:SLIT RS01255
gene id: 580332:SLIT_RS01255
uniprot id: D5CLB0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

580332:SLIT RS11250
gene id: 580332:SLIT_RS11250
uniprot id: D5CLN6
names: Similarity
messages: Belongs to the HesB/IscA family.

580332:SLIT RS12015
gene id: 580332:SLIT_RS12015
uniprot id: D5CMF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

580332:SLIT RS02690
gene id: 580332:SLIT_RS02690
uniprot id: D5CMU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

580332:SLIT RS07900
gene id: 580332:SLIT_RS07900
uniprot id: D5CS78
names: Similarity
messages: Belongs to the leucine-binding protein family.

580332:SLIT RS05040
gene id: 580332:SLIT_RS05040
uniprot id: D5CQL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

580332:SLIT RS02865
gene id: 580332:SLIT_RS02865
uniprot id: D5CMX9
names: Subcellular Location Annotation
messages: Secreted

580332:SLIT RS09185
gene id: 580332:SLIT_RS09185
uniprot id: D5CSX8
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

580332:SLIT RS11285
gene id: 580332:SLIT_RS11285
uniprot id: D5CLP3
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS04035
gene id: 580332:SLIT_RS04035
uniprot id: D5CPA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

580332:SLIT RS03640
gene id: 580332:SLIT_RS03640
uniprot id: D5CNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

580332:SLIT RS09420
gene id: 580332:SLIT_RS09420
uniprot id: D5CT26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

580332:SLIT RS03415
gene id: 580332:SLIT_RS03415
uniprot id: D5CNL3
names: Similarity
messages: Belongs to the bacterial secretin family.

580332:SLIT RS04750
gene id: 580332:SLIT_RS04750
uniprot id: D5CQ26
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

580332:SLIT RS11950
gene id: 580332:SLIT_RS11950
uniprot id: D5CME4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

580332:SLIT RS05325
gene id: 580332:SLIT_RS05325
uniprot id: D5CQR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

580332:SLIT RS08715
gene id: 580332:SLIT_RS08715
uniprot id: D5CSN8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

580332:SLIT RS13310
gene id: 580332:SLIT_RS13310
uniprot id: D5CNX0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

580332:SLIT RS12760
gene id: 580332:SLIT_RS12760
uniprot id: D5CN83
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS03155
gene id: 580332:SLIT_RS03155
uniprot id: D5CNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

580332:SLIT RS08215
gene id: 580332:SLIT_RS08215
uniprot id: D5CSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

580332:SLIT RS00145
gene id: 580332:SLIT_RS00145
uniprot id: D5CTG4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

580332:SLIT RS01445
gene id: 580332:SLIT_RS01445
uniprot id: D5CLE8
names: Similarity
messages: Belongs to the GARS family.

580332:SLIT RS08420
gene id: 580332:SLIT_RS08420
uniprot id: D5CSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

580332:SLIT RS11855
gene id: 580332:SLIT_RS11855
uniprot id: D5CMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

580332:SLIT RS12705
gene id: 580332:SLIT_RS12705
uniprot id: D5CN72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

580332:SLIT RS10270
gene id: 580332:SLIT_RS10270
uniprot id: D5CTX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

580332:SLIT RS14710
gene id: 580332:SLIT_RS14710
uniprot id: D5CQF2
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

580332:SLIT RS11495
gene id: 580332:SLIT_RS11495
uniprot id: D5CLT3
names: Similarity
messages: Belongs to the peptidase S24 family.

580332:SLIT RS13495
gene id: 580332:SLIT_RS13495
uniprot id: D5CP06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

580332:SLIT RS06380
gene id: 580332:SLIT_RS06380
uniprot id: D5CRD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

580332:SLIT RS01430
gene id: 580332:SLIT_RS01430
uniprot id: D5CLE5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

580332:SLIT RS03785
gene id: 580332:SLIT_RS03785
uniprot id: D5CP54
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

580332:SLIT RS07545
gene id: 580332:SLIT_RS07545
uniprot id: D5CS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

580332:SLIT RS02315
gene id: 580332:SLIT_RS02315
uniprot id: D5CM93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS06575
gene id: 580332:SLIT_RS06575
uniprot id: D5CRH1
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS08220
gene id: 580332:SLIT_RS08220
uniprot id: D5CSE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

580332:SLIT RS14935
gene id: 580332:SLIT_RS14935
uniprot id: D5CQJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

580332:SLIT RS14525
gene id: 580332:SLIT_RS14525
uniprot id: D5CQB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

580332:SLIT RS04125
gene id: 580332:SLIT_RS04125
uniprot id: D5CPC3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

580332:SLIT RS01570
gene id: 580332:SLIT_RS01570
uniprot id: D5CLH4
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS11540
gene id: 580332:SLIT_RS11540
uniprot id: D5CLU1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

580332:SLIT RS03885
gene id: 580332:SLIT_RS03885
uniprot id: D5CP74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

580332:SLIT RS05235
gene id: 580332:SLIT_RS05235
uniprot id: D5CQQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03970
gene id: 580332:SLIT_RS03970
uniprot id: D5CP91
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

580332:SLIT RS04120
gene id: 580332:SLIT_RS04120
uniprot id: D5CPC2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

580332:SLIT RS04080
gene id: 580332:SLIT_RS04080
uniprot id: D5CPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

580332:SLIT RS01370
gene id: 580332:SLIT_RS01370
uniprot id: D5CLD3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

580332:SLIT RS07600
gene id: 580332:SLIT_RS07600
uniprot id: D5CS23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

580332:SLIT RS00635
gene id: 580332:SLIT_RS00635
uniprot id: D5CU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

580332:SLIT RS13385
gene id: 580332:SLIT_RS13385
uniprot id: D5CNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

580332:SLIT RS10765
gene id: 580332:SLIT_RS10765
uniprot id: D5CUJ5
names: Similarity
messages: Belongs to the peptidase S16 family.

580332:SLIT RS09905
gene id: 580332:SLIT_RS09905
uniprot id: D5CTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580332:SLIT RS06370
gene id: 580332:SLIT_RS06370
uniprot id: D5CRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

580332:SLIT RS06445
gene id: 580332:SLIT_RS06445
uniprot id: D5CRE6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

580332:SLIT RS00685
gene id: 580332:SLIT_RS00685
uniprot id: D5CU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

580332:SLIT RS10635
gene id: 580332:SLIT_RS10635
uniprot id: D5CUG9
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS03975
gene id: 580332:SLIT_RS03975
uniprot id: D5CP92
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

580332:SLIT RS06985
gene id: 580332:SLIT_RS06985
uniprot id: D5CRQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

580332:SLIT RS02240
gene id: 580332:SLIT_RS02240
uniprot id: D5CM77
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

580332:SLIT RS11800
gene id: 580332:SLIT_RS11800
uniprot id: D5CLZ2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS05735
gene id: 580332:SLIT_RS05735
uniprot id: D5CR03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS09955
gene id: 580332:SLIT_RS09955
uniprot id: D5CTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

580332:SLIT RS05925
gene id: 580332:SLIT_RS05925
uniprot id: D5CR41
names: Similarity
messages: Belongs to the citrate synthase family.

580332:SLIT RS05425
gene id: 580332:SLIT_RS05425
uniprot id: D5CQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

580332:SLIT RS05195
gene id: 580332:SLIT_RS05195
uniprot id: D5CQP2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

580332:SLIT RS03820
gene id: 580332:SLIT_RS03820
uniprot id: D5CP61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

580332:SLIT RS03135
gene id: 580332:SLIT_RS03135
uniprot id: D5CNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

580332:SLIT RS11555
gene id: 580332:SLIT_RS11555
uniprot id: D5CLU4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

580332:SLIT RS05965
gene id: 580332:SLIT_RS05965
uniprot id: D5CR49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

580332:SLIT RS07090
gene id: 580332:SLIT_RS07090
uniprot id: D5CRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

580332:SLIT RS04685
gene id: 580332:SLIT_RS04685
uniprot id: D5CQ13
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS14325
gene id: 580332:SLIT_RS14325
uniprot id: D5CQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

580332:SLIT RS03805
gene id: 580332:SLIT_RS03805
uniprot id: D5CP58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

580332:SLIT RS04260
gene id: 580332:SLIT_RS04260
uniprot id: D5CPE7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

580332:SLIT RS14880
gene id: 580332:SLIT_RS14880
uniprot id: D5CQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

580332:SLIT RS03745
gene id: 580332:SLIT_RS03745
uniprot id: D5CP50
names: Similarity
messages: Belongs to the UPF0758 family.

580332:SLIT RS10325
gene id: 580332:SLIT_RS10325
uniprot id: D5CTY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03520
gene id: 580332:SLIT_RS03520
uniprot id: D5CNN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

580332:SLIT RS13615
gene id: 580332:SLIT_RS13615
uniprot id: D5CP31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

580332:SLIT RS07620
gene id: 580332:SLIT_RS07620
uniprot id: D5CS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

580332:SLIT RS13365
gene id: 580332:SLIT_RS13365
uniprot id: D5CNY1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

580332:SLIT RS10120
gene id: 580332:SLIT_RS10120
uniprot id: D5CTU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

580332:SLIT RS02800
gene id: 580332:SLIT_RS02800
uniprot id: D5CMW6
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

580332:SLIT RS02280
gene id: 580332:SLIT_RS02280
uniprot id: D5CM86
names: Similarity
messages: Belongs to the PhoH family.

580332:SLIT RS01555
gene id: 580332:SLIT_RS01555
uniprot id: D5CLH1
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS13690
gene id: 580332:SLIT_RS13690
uniprot id: D5CP45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

580332:SLIT RS10475
gene id: 580332:SLIT_RS10475
uniprot id: D5CU12
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

580332:SLIT RS00885
gene id: 580332:SLIT_RS00885
uniprot id: D5CU84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

580332:SLIT RS04860
gene id: 580332:SLIT_RS04860
uniprot id: D5CQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS01760
gene id: 580332:SLIT_RS01760
uniprot id: D5CLK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

580332:SLIT RS03915
gene id: 580332:SLIT_RS03915
uniprot id: D5CP80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

580332:SLIT RS07860
gene id: 580332:SLIT_RS07860
uniprot id: D5CS70
names: Similarity
messages: Belongs to the band 7/mec-2 family.

580332:SLIT RS02035
gene id: 580332:SLIT_RS02035
uniprot id: D5CM36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

580332:SLIT RS02820
gene id: 580332:SLIT_RS02820
uniprot id: D5CMX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

580332:SLIT RS12405
gene id: 580332:SLIT_RS12405
uniprot id: D5CMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS04075
gene id: 580332:SLIT_RS04075
uniprot id: D5CPB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

580332:SLIT RS13435
gene id: 580332:SLIT_RS13435
uniprot id: D5CNZ4
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS03270
gene id: 580332:SLIT_RS03270
uniprot id: D5CNI4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

580332:SLIT RS02840
gene id: 580332:SLIT_RS02840
uniprot id: D5CMX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

580332:SLIT RS13890
gene id: 580332:SLIT_RS13890
uniprot id: D5CPL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

580332:SLIT RS06945
gene id: 580332:SLIT_RS06945
uniprot id: D5CRP7
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS04150
gene id: 580332:SLIT_RS04150
uniprot id: D5CPC8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

580332:SLIT RS02925
gene id: 580332:SLIT_RS02925
uniprot id: D5CMZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

580332:SLIT RS04480
gene id: 580332:SLIT_RS04480
uniprot id: D5CPX1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

580332:SLIT RS14140
gene id: 580332:SLIT_RS14140
uniprot id: D5CPR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

580332:SLIT RS12805
gene id: 580332:SLIT_RS12805
uniprot id: D5CN92
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS05390
gene id: 580332:SLIT_RS05390
uniprot id: D5CQT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS02705
gene id: 580332:SLIT_RS02705
uniprot id: D5CMU7
names: Similarity
messages: Belongs to the MotB family.

580332:SLIT RS12040
gene id: 580332:SLIT_RS12040
uniprot id: D5CMG2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS03170
gene id: 580332:SLIT_RS03170
uniprot id: D5CNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS03165
gene id: 580332:SLIT_RS03165
uniprot id: D5CNG3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

580332:SLIT RS02575
gene id: 580332:SLIT_RS02575
uniprot id: D5CMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

580332:SLIT RS04615
gene id: 580332:SLIT_RS04615
uniprot id: D5CPZ8
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

580332:SLIT RS14715
gene id: 580332:SLIT_RS14715
uniprot id: D5CQF3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

580332:SLIT RS12240
gene id: 580332:SLIT_RS12240
uniprot id: D5CMK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

580332:SLIT RS12710
gene id: 580332:SLIT_RS12710
uniprot id: D5CN73
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

580332:SLIT RS05940
gene id: 580332:SLIT_RS05940
uniprot id: D5CR44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

580332:SLIT RS13580
gene id: 580332:SLIT_RS13580
uniprot id: D5CP24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

580332:SLIT RS06410
gene id: 580332:SLIT_RS06410
uniprot id: D5CRD9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

580332:SLIT RS15210
gene id: 580332:SLIT_RS15210
uniprot id: D5CSF5
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS03585
gene id: 580332:SLIT_RS03585
uniprot id: D5CNP6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580332:SLIT RS02845
gene id: 580332:SLIT_RS02845
uniprot id: D5CMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

580332:SLIT RS12600
gene id: 580332:SLIT_RS12600
uniprot id: D5CN50
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

580332:SLIT RS00690
gene id: 580332:SLIT_RS00690
uniprot id: D5CU46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

580332:SLIT RS00925
gene id: 580332:SLIT_RS00925
uniprot id: D5CU92
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

580332:SLIT RS04320
gene id: 580332:SLIT_RS04320
uniprot id: D5CPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS06175
gene id: 580332:SLIT_RS06175
uniprot id: D5CR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

580332:SLIT RS07355
gene id: 580332:SLIT_RS07355
uniprot id: D5CRY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

580332:SLIT RS08250
gene id: 580332:SLIT_RS08250
uniprot id: D5CSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

580332:SLIT RS09365
gene id: 580332:SLIT_RS09365
uniprot id: D5CT14
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS11755
gene id: 580332:SLIT_RS11755
uniprot id: D5CLY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

580332:SLIT RS05955
gene id: 580332:SLIT_RS05955
uniprot id: D5CR47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

580332:SLIT RS07375
gene id: 580332:SLIT_RS07375
uniprot id: D5CRY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

580332:SLIT RS03475
gene id: 580332:SLIT_RS03475
uniprot id: D5CNM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

580332:SLIT RS06630
gene id: 580332:SLIT_RS06630
uniprot id: D5CRI2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

580332:SLIT RS02255
gene id: 580332:SLIT_RS02255
uniprot id: D5CM80
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

580332:SLIT RS03110
gene id: 580332:SLIT_RS03110
uniprot id: D5CNF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

580332:SLIT RS09180
gene id: 580332:SLIT_RS09180
uniprot id: D5CSX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

580332:SLIT RS07095
gene id: 580332:SLIT_RS07095
uniprot id: D5CRS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

580332:SLIT RS00375
gene id: 580332:SLIT_RS00375
uniprot id: D5CTL1
names: Similarity
messages: Belongs to the MipA/OmpV family.

580332:SLIT RS05300
gene id: 580332:SLIT_RS05300
uniprot id: D5CQR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS02635
gene id: 580332:SLIT_RS02635
uniprot id: D5CMT3
names: Similarity
messages: Belongs to the universal stress protein A family.

580332:SLIT RS05035
gene id: 580332:SLIT_RS05035
uniprot id: D5CQL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

580332:SLIT RS10560
gene id: 580332:SLIT_RS10560
uniprot id: D5CU29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

580332:SLIT RS04620
gene id: 580332:SLIT_RS04620
uniprot id: D5CPZ9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

580332:SLIT RS05050
gene id: 580332:SLIT_RS05050
uniprot id: D5CQL3
names: Similarity
messages: Belongs to the thioredoxin family.

580332:SLIT RS10365
gene id: 580332:SLIT_RS10365
uniprot id: D5CTZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

580332:SLIT RS02775
gene id: 580332:SLIT_RS02775
uniprot id: D5CMW1
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

580332:SLIT RS05045
gene id: 580332:SLIT_RS05045
uniprot id: D5CQL2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03275
gene id: 580332:SLIT_RS03275
uniprot id: D5CNI5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

580332:SLIT RS12430
gene id: 580332:SLIT_RS12430
uniprot id: D5CMP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS09335
gene id: 580332:SLIT_RS09335
uniprot id: D5CT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

580332:SLIT RS07050
gene id: 580332:SLIT_RS07050
uniprot id: D5CRS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

580332:SLIT RS05120
gene id: 580332:SLIT_RS05120
uniprot id: D5CQM7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

580332:SLIT RS10610
gene id: 580332:SLIT_RS10610
uniprot id: D5CUG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580332:SLIT RS02080
gene id: 580332:SLIT_RS02080
uniprot id: D5CM45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

580332:SLIT RS03655
gene id: 580332:SLIT_RS03655
uniprot id: D5CNR0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

580332:SLIT RS03900
gene id: 580332:SLIT_RS03900
uniprot id: D5CP77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

580332:SLIT RS03940
gene id: 580332:SLIT_RS03940
uniprot id: D5CP85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

580332:SLIT RS01775
gene id: 580332:SLIT_RS01775
uniprot id: D5CLL0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

580332:SLIT RS03890
gene id: 580332:SLIT_RS03890
uniprot id: D5CP75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

580332:SLIT RS04815
gene id: 580332:SLIT_RS04815
uniprot id: D5CQ38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

580332:SLIT RS08445
gene id: 580332:SLIT_RS08445
uniprot id: D5CSI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

580332:SLIT RS07370
gene id: 580332:SLIT_RS07370
uniprot id: D5CRY5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

580332:SLIT RS12120
gene id: 580332:SLIT_RS12120
uniprot id: D5CMH7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

580332:SLIT RS06450
gene id: 580332:SLIT_RS06450
uniprot id: D5CRE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

580332:SLIT RS11775
gene id: 580332:SLIT_RS11775
uniprot id: D5CLY7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

580332:SLIT RS13590
gene id: 580332:SLIT_RS13590
uniprot id: D5CP26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS03740
gene id: 580332:SLIT_RS03740
uniprot id: D5CP49
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03085
gene id: 580332:SLIT_RS03085
uniprot id: D5CN24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

580332:SLIT RS10645
gene id: 580332:SLIT_RS10645
uniprot id: D5CUH1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

580332:SLIT RS12280
gene id: 580332:SLIT_RS12280
uniprot id: D5CMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

580332:SLIT RS12560
gene id: 580332:SLIT_RS12560
uniprot id: D5CN42
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS02900
gene id: 580332:SLIT_RS02900
uniprot id: D5CMY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

580332:SLIT RS13730
gene id: 580332:SLIT_RS13730
uniprot id: D5CPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

580332:SLIT RS12525
gene id: 580332:SLIT_RS12525
uniprot id: D5CN34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

580332:SLIT RS01670
gene id: 580332:SLIT_RS01670
uniprot id: D5CLJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

580332:SLIT RS08265
gene id: 580332:SLIT_RS08265
uniprot id: D5CSF0
names: Similarity
messages: Belongs to the P(II) protein family.

580332:SLIT RS13785
gene id: 580332:SLIT_RS13785
uniprot id: D5CPJ0
names: Similarity
messages: Belongs to the GSP E family.

580332:SLIT RS03955
gene id: 580332:SLIT_RS03955
uniprot id: D5CP88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

580332:SLIT RS02875
gene id: 580332:SLIT_RS02875
uniprot id: D5CMY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

580332:SLIT RS07485
gene id: 580332:SLIT_RS07485
uniprot id: D5CS06
names: Similarity
messages: Belongs to the RecJ family.

580332:SLIT RS14640
gene id: 580332:SLIT_RS14640
uniprot id: D5CQD9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

580332:SLIT RS05995
gene id: 580332:SLIT_RS05995
uniprot id: D5CR55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

580332:SLIT RS11825
gene id: 580332:SLIT_RS11825
uniprot id: D5CLZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

580332:SLIT RS07150
gene id: 580332:SLIT_RS07150
uniprot id: D5CRU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

580332:SLIT RS02555
gene id: 580332:SLIT_RS02555
uniprot id: D5CMS0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

580332:SLIT RS04700
gene id: 580332:SLIT_RS04700
uniprot id: D5CQ16
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

580332:SLIT RS02695
gene id: 580332:SLIT_RS02695
uniprot id: D5CMU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

580332:SLIT RS04005
gene id: 580332:SLIT_RS04005
uniprot id: D5CP98
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

580332:SLIT RS08030
gene id: 580332:SLIT_RS08030
uniprot id: D5CSA2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS11745
gene id: 580332:SLIT_RS11745
uniprot id: D5CLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

580332:SLIT RS05655
gene id: 580332:SLIT_RS05655
uniprot id: D5CQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

580332:SLIT RS09845
gene id: 580332:SLIT_RS09845
uniprot id: D5CTB3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS00090
gene id: 580332:SLIT_RS00090
uniprot id: D5CTF3
names: Similarity
messages: Belongs to the pyruvate kinase family.

580332:SLIT RS11195
gene id: 580332:SLIT_RS11195
uniprot id: D5CUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS04890
gene id: 580332:SLIT_RS04890
uniprot id: D5CQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

580332:SLIT RS04325
gene id: 580332:SLIT_RS04325
uniprot id: D5CPG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS06920
gene id: 580332:SLIT_RS06920
uniprot id: D5CRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

580332:SLIT RS08130
gene id: 580332:SLIT_RS08130
uniprot id: D5CSC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS06310
gene id: 580332:SLIT_RS06310
uniprot id: D5CRB8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

580332:SLIT RS13740
gene id: 580332:SLIT_RS13740
uniprot id: D5CPI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

580332:SLIT RS03945
gene id: 580332:SLIT_RS03945
uniprot id: D5CP86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

580332:SLIT RS07640
gene id: 580332:SLIT_RS07640
uniprot id: D5CS31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

580332:SLIT RS13735
gene id: 580332:SLIT_RS13735
uniprot id: D5CPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

580332:SLIT RS06395
gene id: 580332:SLIT_RS06395
uniprot id: D5CRD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

580332:SLIT RS06240
gene id: 580332:SLIT_RS06240
uniprot id: D5CRA4
names: Similarity
messages: Belongs to the asparagine synthetase family.

580332:SLIT RS13540
gene id: 580332:SLIT_RS13540
uniprot id: D5CP16
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

580332:SLIT RS14825
gene id: 580332:SLIT_RS14825
uniprot id: D5CQH6
names: Similarity
messages: Belongs to the YjdM family.

580332:SLIT RS11870
gene id: 580332:SLIT_RS11870
uniprot id: D5CMC9
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

580332:SLIT RS11965
gene id: 580332:SLIT_RS11965
uniprot id: D5CME7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS06570
gene id: 580332:SLIT_RS06570
uniprot id: D5CRH0
names: Similarity
messages: Belongs to the UPF0178 family.

580332:SLIT RS07000
gene id: 580332:SLIT_RS07000
uniprot id: D5CRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

580332:SLIT RS05950
gene id: 580332:SLIT_RS05950
uniprot id: D5CR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

580332:SLIT RS00155
gene id: 580332:SLIT_RS00155
uniprot id: D5CTG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

580332:SLIT RS03855
gene id: 580332:SLIT_RS03855
uniprot id: D5CP68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

580332:SLIT RS00680
gene id: 580332:SLIT_RS00680
uniprot id: D5CU44
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

580332:SLIT RS02905
gene id: 580332:SLIT_RS02905
uniprot id: D5CMY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

580332:SLIT RS08670
gene id: 580332:SLIT_RS08670
uniprot id: D5CSN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

580332:SLIT RS00915
gene id: 580332:SLIT_RS00915
uniprot id: D5CU90
names: Similarity
messages: Belongs to the peptidase S13 family.

580332:SLIT RS07490
gene id: 580332:SLIT_RS07490
uniprot id: D5CS07
names: Similarity
messages: Belongs to the aspartokinase family.

580332:SLIT RS02590
gene id: 580332:SLIT_RS02590
uniprot id: D5CMS7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS04430
gene id: 580332:SLIT_RS04430
uniprot id: D5CPW0
names: Similarity
messages: Belongs to the NifX/NifY family.

580332:SLIT RS03265
gene id: 580332:SLIT_RS03265
uniprot id: D5CNI3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

580332:SLIT RS05175
gene id: 580332:SLIT_RS05175
uniprot id: D5CQN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

580332:SLIT RS12905
gene id: 580332:SLIT_RS12905
uniprot id: D5CNB1
names: Similarity
messages: Belongs to the SCO1/2 family.

580332:SLIT RS13525
gene id: 580332:SLIT_RS13525
uniprot id: D5CP12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

580332:SLIT RS05250
gene id: 580332:SLIT_RS05250
uniprot id: D5CQQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

580332:SLIT RS13140
gene id: 580332:SLIT_RS13140
uniprot id: D5CNT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

580332:SLIT RS12860
gene id: 580332:SLIT_RS12860
uniprot id: D5CNA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

580332:SLIT RS12105
gene id: 580332:SLIT_RS12105
uniprot id: D5CMH4
names: Similarity
messages: Belongs to the HypD family.

580332:SLIT RS02965
gene id: 580332:SLIT_RS02965
uniprot id: D5CMZ9
names: Subcellular Location Annotation
messages: Cytoplasm

580332:SLIT RS02005
gene id: 580332:SLIT_RS02005
uniprot id: D5CM30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

580332:SLIT RS08870
gene id: 580332:SLIT_RS08870
uniprot id: D5CSS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS08650
gene id: 580332:SLIT_RS08650
uniprot id: D5CSM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

580332:SLIT RS06390
gene id: 580332:SLIT_RS06390
uniprot id: D5CRD5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

580332:SLIT RS00075
gene id: 580332:SLIT_RS00075
uniprot id: D5CTF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

580332:SLIT RS03995
gene id: 580332:SLIT_RS03995
uniprot id: D5CP96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

580332:SLIT RS13300
gene id: 580332:SLIT_RS13300
uniprot id: D5CNW8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

580332:SLIT RS00130
gene id: 580332:SLIT_RS00130
uniprot id: D5CTG1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS10605
gene id: 580332:SLIT_RS10605
uniprot id: D5CUG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS06820
gene id: 580332:SLIT_RS06820
uniprot id: D5CRM1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

580332:SLIT RS01440
gene id: 580332:SLIT_RS01440
uniprot id: D5CLE7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

580332:SLIT RS08225
gene id: 580332:SLIT_RS08225
uniprot id: D5CSE2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS07725
gene id: 580332:SLIT_RS07725
uniprot id: D5CS46
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS04925
gene id: 580332:SLIT_RS04925
uniprot id: D5CQ60
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

580332:SLIT RS02330
gene id: 580332:SLIT_RS02330
uniprot id: D5CM96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

580332:SLIT RS08925
gene id: 580332:SLIT_RS08925
uniprot id: D5CST0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

580332:SLIT RS00180
gene id: 580332:SLIT_RS00180
uniprot id: D5CTH0
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS02260
gene id: 580332:SLIT_RS02260
uniprot id: D5CM81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS11445
gene id: 580332:SLIT_RS11445
uniprot id: D5CLS4
names: Similarity
messages: Belongs to the FeoA family.

580332:SLIT RS13040
gene id: 580332:SLIT_RS13040
uniprot id: D5CND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

580332:SLIT RS10345
gene id: 580332:SLIT_RS10345
uniprot id: D5CTY7
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS03875
gene id: 580332:SLIT_RS03875
uniprot id: D5CP72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

580332:SLIT RS01315
gene id: 580332:SLIT_RS01315
uniprot id: D5CLC2
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

580332:SLIT RS09875
gene id: 580332:SLIT_RS09875
uniprot id: D5CTB9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS09315
gene id: 580332:SLIT_RS09315
uniprot id: D5CT04
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

580332:SLIT RS00475
gene id: 580332:SLIT_RS00475
uniprot id: D5CTN2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

580332:SLIT RS10520
gene id: 580332:SLIT_RS10520
uniprot id: D5CU21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

580332:SLIT RS09780
gene id: 580332:SLIT_RS09780
uniprot id: D5CT98
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

580332:SLIT RS12920
gene id: 580332:SLIT_RS12920
uniprot id: D5CNB4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

580332:SLIT RS10315
gene id: 580332:SLIT_RS10315
uniprot id: D5CTY1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

580332:SLIT RS05930
gene id: 580332:SLIT_RS05930
uniprot id: D5CR42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

580332:SLIT RS02620
gene id: 580332:SLIT_RS02620
uniprot id: D5CMT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

580332:SLIT RS13670
gene id: 580332:SLIT_RS13670
uniprot id: D5CP41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

580332:SLIT RS03680
gene id: 580332:SLIT_RS03680
uniprot id: D5CNR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

580332:SLIT RS11625
gene id: 580332:SLIT_RS11625
uniprot id: D5CLV8
names: Similarity
messages: Belongs to the AHA1 family.

580332:SLIT RS12000
gene id: 580332:SLIT_RS12000
uniprot id: D5CMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

580332:SLIT RS14200
gene id: 580332:SLIT_RS14200
uniprot id: D5CPS4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

580332:SLIT RS12175
gene id: 580332:SLIT_RS12175
uniprot id: D5CMI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

580332:SLIT RS10185
gene id: 580332:SLIT_RS10185
uniprot id: D5CTV4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

580332:SLIT RS13710
gene id: 580332:SLIT_RS13710
uniprot id: D5CPH5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

580332:SLIT RS14150
gene id: 580332:SLIT_RS14150
uniprot id: D5CPR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

580332:SLIT RS00230
gene id: 580332:SLIT_RS00230
uniprot id: D5CTI0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

580332:SLIT RS08205
gene id: 580332:SLIT_RS08205
uniprot id: D5CSD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

580332:SLIT RS09980
gene id: 580332:SLIT_RS09980
uniprot id: D5CTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

580332:SLIT RS03660
gene id: 580332:SLIT_RS03660
uniprot id: D5CNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

580332:SLIT RS00080
gene id: 580332:SLIT_RS00080
uniprot id: D5CTF1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

580332:SLIT RS11940
gene id: 580332:SLIT_RS11940
uniprot id: D5CME2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS09390
gene id: 580332:SLIT_RS09390
uniprot id: D5CT20
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

580332:SLIT RS08545
gene id: 580332:SLIT_RS08545
uniprot id: D5CSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

580332:SLIT RS10335
gene id: 580332:SLIT_RS10335
uniprot id: D5CTY5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

580332:SLIT RS00310
gene id: 580332:SLIT_RS00310
uniprot id: D5CTJ7
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS04745
gene id: 580332:SLIT_RS04745
uniprot id: D5CQ25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

580332:SLIT RS07350
gene id: 580332:SLIT_RS07350
uniprot id: D5CRY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

580332:SLIT RS11980
gene id: 580332:SLIT_RS11980
uniprot id: D5CMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS08735
gene id: 580332:SLIT_RS08735
uniprot id: D5CSP2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

580332:SLIT RS09230
gene id: 580332:SLIT_RS09230
uniprot id: D5CSY7
names: Similarity
messages: Belongs to the MEMO1 family.

580332:SLIT RS10380
gene id: 580332:SLIT_RS10380
uniprot id: D5CTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

580332:SLIT RS08040
gene id: 580332:SLIT_RS08040
uniprot id: D5CSA4
names: Similarity
messages: Belongs to the thioredoxin family.

580332:SLIT RS06785
gene id: 580332:SLIT_RS06785
uniprot id: D5CRL4
names: Similarity
messages: Belongs to the UPF0434 family.

580332:SLIT RS06705
gene id: 580332:SLIT_RS06705
uniprot id: D5CRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

580332:SLIT RS08490
gene id: 580332:SLIT_RS08490
uniprot id: D5CSJ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

580332:SLIT RS13330
gene id: 580332:SLIT_RS13330
uniprot id: D5CNX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

580332:SLIT RS02560
gene id: 580332:SLIT_RS02560
uniprot id: D5CMS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

580332:SLIT RS10740
gene id: 580332:SLIT_RS10740
uniprot id: D5CUJ0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

580332:SLIT RS13720
gene id: 580332:SLIT_RS13720
uniprot id: D5CPH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

580332:SLIT RS07360
gene id: 580332:SLIT_RS07360
uniprot id: D5CRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

580332:SLIT RS14210
gene id: 580332:SLIT_RS14210
uniprot id: D5CPS6
names: Similarity
messages: Belongs to the phosphoribulokinase family.

580332:SLIT RS11765
gene id: 580332:SLIT_RS11765
uniprot id: D5CLY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

580332:SLIT RS13470
gene id: 580332:SLIT_RS13470
uniprot id: D5CP01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

580332:SLIT RS12400
gene id: 580332:SLIT_RS12400
uniprot id: D5CMN4
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS14870
gene id: 580332:SLIT_RS14870
uniprot id: D5CQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

580332:SLIT RS14475
gene id: 580332:SLIT_RS14475
uniprot id: D5CQA4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

580332:SLIT RS15125
gene id: 580332:SLIT_RS15125
uniprot id: D5CR35
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

580332:SLIT RS03000
gene id: 580332:SLIT_RS03000
uniprot id: D5CN07
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

580332:SLIT RS14155
gene id: 580332:SLIT_RS14155
uniprot id: D5CPR4
names: Similarity
messages: Belongs to the LOG family.

580332:SLIT RS11630
gene id: 580332:SLIT_RS11630
uniprot id: D5CLV9
names: Similarity
messages: Belongs to the AHA1 family.

580332:SLIT RS10685
gene id: 580332:SLIT_RS10685
uniprot id: D5CUH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

580332:SLIT RS10445
gene id: 580332:SLIT_RS10445
uniprot id: D5CU06
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

580332:SLIT RS09040
gene id: 580332:SLIT_RS09040
uniprot id: D5CSV0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

580332:SLIT RS11180
gene id: 580332:SLIT_RS11180
uniprot id: D5CUT0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

580332:SLIT RS10240
gene id: 580332:SLIT_RS10240
uniprot id: D5CTW6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS03075
gene id: 580332:SLIT_RS03075
uniprot id: D5CN22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

580332:SLIT RS01375
gene id: 580332:SLIT_RS01375
uniprot id: D5CLD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

580332:SLIT RS01645
gene id: 580332:SLIT_RS01645
uniprot id: D5CLI8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

580332:SLIT RS03230
gene id: 580332:SLIT_RS03230
uniprot id: D5CNH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

580332:SLIT RS14315
gene id: 580332:SLIT_RS14315
uniprot id: D5CPU8
names: Similarity
messages: Belongs to the fructosamine kinase family.

580332:SLIT RS11590
gene id: 580332:SLIT_RS11590
uniprot id: D5CLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

580332:SLIT RS06800
gene id: 580332:SLIT_RS06800
uniprot id: D5CRL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

580332:SLIT RS07710
gene id: 580332:SLIT_RS07710
uniprot id: D5CS43
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

580332:SLIT RS08485
gene id: 580332:SLIT_RS08485
uniprot id: D5CSJ3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

580332:SLIT RS12795
gene id: 580332:SLIT_RS12795
uniprot id: D5CN90
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS10180
gene id: 580332:SLIT_RS10180
uniprot id: D5CTV3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

580332:SLIT RS05920
gene id: 580332:SLIT_RS05920
uniprot id: D5CR40
names: Similarity
messages: Belongs to the PrpD family.

580332:SLIT RS01840
gene id: 580332:SLIT_RS01840
uniprot id: D5CLM2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS11580
gene id: 580332:SLIT_RS11580
uniprot id: D5CLU9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

580332:SLIT RS02790
gene id: 580332:SLIT_RS02790
uniprot id: D5CMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

580332:SLIT RS10710
gene id: 580332:SLIT_RS10710
uniprot id: D5CUI3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

580332:SLIT RS08530
gene id: 580332:SLIT_RS08530
uniprot id: D5CSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

580332:SLIT RS04030
gene id: 580332:SLIT_RS04030
uniprot id: D5CPA3
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

580332:SLIT RS08740
gene id: 580332:SLIT_RS08740
uniprot id: D5CSP3
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS08515
gene id: 580332:SLIT_RS08515
uniprot id: D5CSJ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

580332:SLIT RS04840
gene id: 580332:SLIT_RS04840
uniprot id: D5CQ43
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

580332:SLIT RS06070
gene id: 580332:SLIT_RS06070
uniprot id: D5CR70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

580332:SLIT RS14650
gene id: 580332:SLIT_RS14650
uniprot id: D5CQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

580332:SLIT RS07985
gene id: 580332:SLIT_RS07985
uniprot id: D5CS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

580332:SLIT RS10215
gene id: 580332:SLIT_RS10215
uniprot id: D5CTW1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580332:SLIT RS00270
gene id: 580332:SLIT_RS00270
uniprot id: D5CTI8
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

580332:SLIT RS11935
gene id: 580332:SLIT_RS11935
uniprot id: D5CME1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

580332:SLIT RS15095
gene id: 580332:SLIT_RS15095
uniprot id: D5CQ07
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS08820
gene id: 580332:SLIT_RS08820
uniprot id: D5CSR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

580332:SLIT RS12010
gene id: 580332:SLIT_RS12010
uniprot id: D5CMF6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS04405
gene id: 580332:SLIT_RS04405
uniprot id: D5CPV5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

580332:SLIT RS09055
gene id: 580332:SLIT_RS09055
uniprot id: D5CSV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

580332:SLIT RS07695
gene id: 580332:SLIT_RS07695
uniprot id: D5CS40
names: Similarity
messages: Belongs to the histone deacetylase family.

580332:SLIT RS00735
gene id: 580332:SLIT_RS00735
uniprot id: D5CU55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS02440
gene id: 580332:SLIT_RS02440
uniprot id: D5CMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS02435
gene id: 580332:SLIT_RS02435
uniprot id: D5CMB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS08950
gene id: 580332:SLIT_RS08950
uniprot id: D5CST4
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

580332:SLIT RS13635
gene id: 580332:SLIT_RS13635
uniprot id: D5CP35
names: Similarity
messages: Belongs to the GppA/Ppx family.

580332:SLIT RS00805
gene id: 580332:SLIT_RS00805
uniprot id: D5CU68
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

580332:SLIT RS04410
gene id: 580332:SLIT_RS04410
uniprot id: D5CPV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

580332:SLIT RS11720
gene id: 580332:SLIT_RS11720
uniprot id: D5CLX7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

580332:SLIT RS14580
gene id: 580332:SLIT_RS14580
uniprot id: D5CQC6
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS00110
gene id: 580332:SLIT_RS00110
uniprot id: D5CTF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

580332:SLIT RS13445
gene id: 580332:SLIT_RS13445
uniprot id: D5CNZ6
names: Similarity
messages: Belongs to the leucine-binding protein family.

580332:SLIT RS09240
gene id: 580332:SLIT_RS09240
uniprot id: D5CSY9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

580332:SLIT RS02170
gene id: 580332:SLIT_RS02170
uniprot id: D5CM63
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

580332:SLIT RS07630
gene id: 580332:SLIT_RS07630
uniprot id: D5CS29
names: Similarity
messages: Belongs to the fabD family.

580332:SLIT RS08725
gene id: 580332:SLIT_RS08725
uniprot id: D5CSP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

580332:SLIT RS00560
gene id: 580332:SLIT_RS00560
uniprot id: D5CTP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

580332:SLIT RS14450
gene id: 580332:SLIT_RS14450
uniprot id: D5CQ99
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

580332:SLIT RS12835
gene id: 580332:SLIT_RS12835
uniprot id: D5CN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

580332:SLIT RS08785
gene id: 580332:SLIT_RS08785
uniprot id: D5CSQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

580332:SLIT RS00845
gene id: 580332:SLIT_RS00845
uniprot id: D5CU76
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

580332:SLIT RS02980
gene id: 580332:SLIT_RS02980
uniprot id: D5CN02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

580332:SLIT RS08370
gene id: 580332:SLIT_RS08370
uniprot id: D5CSH1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

580332:SLIT RS05350
gene id: 580332:SLIT_RS05350
uniprot id: D5CQS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS10125
gene id: 580332:SLIT_RS10125
uniprot id: D5CTU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

580332:SLIT RS05410
gene id: 580332:SLIT_RS05410
uniprot id: D5CQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

580332:SLIT RS07155
gene id: 580332:SLIT_RS07155
uniprot id: D5CRU1
names: Similarity
messages: Belongs to the ArsC family.

580332:SLIT RS06290
gene id: 580332:SLIT_RS06290
uniprot id: D5CRB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

580332:SLIT RS13485
gene id: 580332:SLIT_RS13485
uniprot id: D5CP04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

580332:SLIT RS02770
gene id: 580332:SLIT_RS02770
uniprot id: D5CMW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

580332:SLIT RS14600
gene id: 580332:SLIT_RS14600
uniprot id: D5CQD0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

580332:SLIT RS03235
gene id: 580332:SLIT_RS03235
uniprot id: D5CNH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS04950
gene id: 580332:SLIT_RS04950
uniprot id: D5CQ65
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

580332:SLIT RS05090
gene id: 580332:SLIT_RS05090
uniprot id: D5CQM1
names: Similarity
messages: Belongs to the UPF0234 family.

580332:SLIT RS01695
gene id: 580332:SLIT_RS01695
uniprot id: D5CLJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

580332:SLIT RS00670
gene id: 580332:SLIT_RS00670
uniprot id: D5CU42
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

580332:SLIT RS04330
gene id: 580332:SLIT_RS04330
uniprot id: D5CPG1
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

580332:SLIT RS02765
gene id: 580332:SLIT_RS02765
uniprot id: D5CMV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

580332:SLIT RS00460
gene id: 580332:SLIT_RS00460
uniprot id: D5CTM9
names: Similarity
messages: Belongs to the creatininase superfamily.

580332:SLIT RS14930
gene id: 580332:SLIT_RS14930
uniprot id: D5CQJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03200
gene id: 580332:SLIT_RS03200
uniprot id: D5CNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

580332:SLIT RS03245
gene id: 580332:SLIT_RS03245
uniprot id: D5CNH9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

580332:SLIT RS03340
gene id: 580332:SLIT_RS03340
uniprot id: D5CNJ8
names: Similarity
messages: Belongs to the YkuD family.

580332:SLIT RS12250
gene id: 580332:SLIT_RS12250
uniprot id: D5CMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS06875
gene id: 580332:SLIT_RS06875
uniprot id: D5CRN2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS10260
gene id: 580332:SLIT_RS10260
uniprot id: D5CTX0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

580332:SLIT RS04790
gene id: 580332:SLIT_RS04790
uniprot id: D5CQ33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

580332:SLIT RS09190
gene id: 580332:SLIT_RS09190
uniprot id: D5CSX9
names: Similarity
messages: Belongs to the citrate synthase family.

580332:SLIT RS02455
gene id: 580332:SLIT_RS02455
uniprot id: D5CMC0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

580332:SLIT RS10165
gene id: 580332:SLIT_RS10165
uniprot id: D5CTV0
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS08565
gene id: 580332:SLIT_RS08565
uniprot id: D5CSK9
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

580332:SLIT RS00050
gene id: 580332:SLIT_RS00050
uniprot id: D5CTE5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

580332:SLIT RS08665
gene id: 580332:SLIT_RS08665
uniprot id: D5CSM9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

580332:SLIT RS11560
gene id: 580332:SLIT_RS11560
uniprot id: D5CLU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

580332:SLIT RS08160
gene id: 580332:SLIT_RS08160
uniprot id: D5CSC9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

580332:SLIT RS05095
gene id: 580332:SLIT_RS05095
uniprot id: D5CQM2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

580332:SLIT RS02860
gene id: 580332:SLIT_RS02860
uniprot id: D5CMX8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

580332:SLIT RS01260
gene id: 580332:SLIT_RS01260
uniprot id: D5CLB1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

580332:SLIT RS14485
gene id: 580332:SLIT_RS14485
uniprot id: D5CQA6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03130
gene id: 580332:SLIT_RS03130
uniprot id: D5CNF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS13575
gene id: 580332:SLIT_RS13575
uniprot id: D5CP23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS12700
gene id: 580332:SLIT_RS12700
uniprot id: D5CN71
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS02855
gene id: 580332:SLIT_RS02855
uniprot id: D5CMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

580332:SLIT RS12025
gene id: 580332:SLIT_RS12025
uniprot id: D5CMF9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

580332:SLIT RS03470
gene id: 580332:SLIT_RS03470
uniprot id: D5CNM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

580332:SLIT RS08240
gene id: 580332:SLIT_RS08240
uniprot id: D5CSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

580332:SLIT RS09260
gene id: 580332:SLIT_RS09260
uniprot id: D5CSZ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

580332:SLIT RS07335
gene id: 580332:SLIT_RS07335
uniprot id: D5CRX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS02920
gene id: 580332:SLIT_RS02920
uniprot id: D5CMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

580332:SLIT RS03220
gene id: 580332:SLIT_RS03220
uniprot id: D5CNH4
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

580332:SLIT RS02015
gene id: 580332:SLIT_RS02015
uniprot id: D5CM32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

580332:SLIT RS13295
gene id: 580332:SLIT_RS13295
uniprot id: D5CNW7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

580332:SLIT RS02930
gene id: 580332:SLIT_RS02930
uniprot id: D5CMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

580332:SLIT RS06855
gene id: 580332:SLIT_RS06855
uniprot id: D5CRM8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

580332:SLIT RS05670
gene id: 580332:SLIT_RS05670
uniprot id: D5CQY5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS07030
gene id: 580332:SLIT_RS07030
uniprot id: D5CRR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS00335
gene id: 580332:SLIT_RS00335
uniprot id: D5CTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS00085
gene id: 580332:SLIT_RS00085
uniprot id: D5CTF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580332:SLIT RS00190
gene id: 580332:SLIT_RS00190
uniprot id: D5CTH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

580332:SLIT RS11245
gene id: 580332:SLIT_RS11245
uniprot id: D5CLN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

580332:SLIT RS00520
gene id: 580332:SLIT_RS00520
uniprot id: D5CTP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

580332:SLIT RS03460
gene id: 580332:SLIT_RS03460
uniprot id: D5CNM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

580332:SLIT RS11995
gene id: 580332:SLIT_RS11995
uniprot id: D5CMF3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

580332:SLIT RS13560
gene id: 580332:SLIT_RS13560
uniprot id: D5CP20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

580332:SLIT RS08235
gene id: 580332:SLIT_RS08235
uniprot id: D5CSE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

580332:SLIT RS14165
gene id: 580332:SLIT_RS14165
uniprot id: D5CPR6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

580332:SLIT RS01310
gene id: 580332:SLIT_RS01310
uniprot id: D5CLC1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

580332:SLIT RS06730
gene id: 580332:SLIT_RS06730
uniprot id: D5CRK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

580332:SLIT RS15300
gene id: 580332:SLIT_RS15300
uniprot id: D5CU03
names: Similarity
messages: Belongs to the PilY1 family.

580332:SLIT RS11975
gene id: 580332:SLIT_RS11975
uniprot id: D5CME9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS03405
gene id: 580332:SLIT_RS03405
uniprot id: D5CNL1
names: Similarity
messages: Belongs to the GSP E family.

580332:SLIT RS07660
gene id: 580332:SLIT_RS07660
uniprot id: D5CS35
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

580332:SLIT RS13600
gene id: 580332:SLIT_RS13600
uniprot id: D5CP28
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03105
gene id: 580332:SLIT_RS03105
uniprot id: D5CNF1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

580332:SLIT RS01365
gene id: 580332:SLIT_RS01365
uniprot id: D5CLD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

580332:SLIT RS12300
gene id: 580332:SLIT_RS12300
uniprot id: D5CML2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

580332:SLIT RS00555
gene id: 580332:SLIT_RS00555
uniprot id: D5CTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

580332:SLIT RS04785
gene id: 580332:SLIT_RS04785
uniprot id: D5CQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

580332:SLIT RS10370
gene id: 580332:SLIT_RS10370
uniprot id: D5CTZ2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

580332:SLIT RS14350
gene id: 580332:SLIT_RS14350
uniprot id: D5CQ79
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS09210
gene id: 580332:SLIT_RS09210
uniprot id: D5CSY3
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

580332:SLIT RS01325
gene id: 580332:SLIT_RS01325
uniprot id: D5CLC4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

580332:SLIT RS11890
gene id: 580332:SLIT_RS11890
uniprot id: D5CMD3
names: Similarity
messages: Belongs to the peptidase U62 family.

580332:SLIT RS14235
gene id: 580332:SLIT_RS14235
uniprot id: D5CPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

580332:SLIT RS06230
gene id: 580332:SLIT_RS06230
uniprot id: D5CRA2
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

580332:SLIT RS02125
gene id: 580332:SLIT_RS02125
uniprot id: D5CM54
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

580332:SLIT RS05225
gene id: 580332:SLIT_RS05225
uniprot id: D5CQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

580332:SLIT RS06495
gene id: 580332:SLIT_RS06495
uniprot id: D5CRF6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

580332:SLIT RS13545
gene id: 580332:SLIT_RS13545
uniprot id: D5CP17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS11840
gene id: 580332:SLIT_RS11840
uniprot id: D5CMC3
names: Similarity
messages: Belongs to the peptidase M16 family.

580332:SLIT RS05675
gene id: 580332:SLIT_RS05675
uniprot id: D5CQY6
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS02510
gene id: 580332:SLIT_RS02510
uniprot id: D5CMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

580332:SLIT RS13640
gene id: 580332:SLIT_RS13640
uniprot id: D5CP36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

580332:SLIT RS07005
gene id: 580332:SLIT_RS07005
uniprot id: D5CRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

580332:SLIT RS12880
gene id: 580332:SLIT_RS12880
uniprot id: D5CNA6
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

580332:SLIT RS02465
gene id: 580332:SLIT_RS02465
uniprot id: D5CMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS09350
gene id: 580332:SLIT_RS09350
uniprot id: D5CT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

580332:SLIT RS03925
gene id: 580332:SLIT_RS03925
uniprot id: D5CP82
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

580332:SLIT RS00660
gene id: 580332:SLIT_RS00660
uniprot id: D5CU40
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

580332:SLIT RS14335
gene id: 580332:SLIT_RS14335
uniprot id: D5CQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

580332:SLIT RS14095
gene id: 580332:SLIT_RS14095
uniprot id: D5CPQ2
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS11450
gene id: 580332:SLIT_RS11450
uniprot id: D5CLS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

580332:SLIT RS04605
gene id: 580332:SLIT_RS04605
uniprot id: D5CPZ6
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS07400
gene id: 580332:SLIT_RS07400
uniprot id: D5CRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

580332:SLIT RS03735
gene id: 580332:SLIT_RS03735
uniprot id: D5CP48
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

580332:SLIT RS00650
gene id: 580332:SLIT_RS00650
uniprot id: D5CU38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

580332:SLIT RS06405
gene id: 580332:SLIT_RS06405
uniprot id: D5CRD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

580332:SLIT RS05660
gene id: 580332:SLIT_RS05660
uniprot id: D5CQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

580332:SLIT RS13355
gene id: 580332:SLIT_RS13355
uniprot id: D5CNX9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

580332:SLIT RS04590
gene id: 580332:SLIT_RS04590
uniprot id: D5CPZ3
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS02390
gene id: 580332:SLIT_RS02390
uniprot id: D5CMA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

580332:SLIT RS02385
gene id: 580332:SLIT_RS02385
uniprot id: D5CMA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

580332:SLIT RS04930
gene id: 580332:SLIT_RS04930
uniprot id: D5CQ61
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

580332:SLIT RS02975
gene id: 580332:SLIT_RS02975
uniprot id: D5CN01
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

580332:SLIT RS00295
gene id: 580332:SLIT_RS00295
uniprot id: D5CTJ4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

580332:SLIT RS03160
gene id: 580332:SLIT_RS03160
uniprot id: D5CNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

580332:SLIT RS02360
gene id: 580332:SLIT_RS02360
uniprot id: D5CMA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

580332:SLIT RS04910
gene id: 580332:SLIT_RS04910
uniprot id: D5CQ57
names: Similarity
messages: Belongs to the peptidase S11 family.

580332:SLIT RS00030
gene id: 580332:SLIT_RS00030
uniprot id: D5CTE1
names: Similarity
messages: Belongs to the Smg family.

580332:SLIT RS11860
gene id: 580332:SLIT_RS11860
uniprot id: D5CMC7
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS06425
gene id: 580332:SLIT_RS06425
uniprot id: D5CRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

580332:SLIT RS13505
gene id: 580332:SLIT_RS13505
uniprot id: D5CP08
names: Similarity
messages: Belongs to the Nudix hydrolase family.

580332:SLIT RS11780
gene id: 580332:SLIT_RS11780
uniprot id: D5CLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

580332:SLIT RS14510
gene id: 580332:SLIT_RS14510
uniprot id: D5CQB1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

580332:SLIT RS06305
gene id: 580332:SLIT_RS06305
uniprot id: D5CRB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

580332:SLIT RS11155
gene id: 580332:SLIT_RS11155
uniprot id: D5CUS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

580332:SLIT RS06685
gene id: 580332:SLIT_RS06685
uniprot id: D5CRJ3
names: Similarity
messages: Belongs to the glyoxalase I family.

580332:SLIT RS00465
gene id: 580332:SLIT_RS00465
uniprot id: D5CTN0
names: Similarity
messages: Belongs to the glutamine synthetase family.

580332:SLIT RS06815
gene id: 580332:SLIT_RS06815
uniprot id: D5CRM0
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS10310
gene id: 580332:SLIT_RS10310
uniprot id: D5CTY0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

580332:SLIT RS02985
gene id: 580332:SLIT_RS02985
uniprot id: D5CN03
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

580332:SLIT RS00290
gene id: 580332:SLIT_RS00290
uniprot id: D5CTJ3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

580332:SLIT RS10190
gene id: 580332:SLIT_RS10190
uniprot id: D5CTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

580332:SLIT RS08085
gene id: 580332:SLIT_RS08085
uniprot id: D5CSB4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

580332:SLIT RS06885
gene id: 580332:SLIT_RS06885
uniprot id: D5CRN4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

580332:SLIT RS02220
gene id: 580332:SLIT_RS02220
uniprot id: D5CM73
names: Similarity
messages: Belongs to the MQO family.

580332:SLIT RS00725
gene id: 580332:SLIT_RS00725
uniprot id: D5CU53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

580332:SLIT RS03780
gene id: 580332:SLIT_RS03780
uniprot id: D5CP53
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

580332:SLIT RS11485
gene id: 580332:SLIT_RS11485
uniprot id: D5CLT1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

580332:SLIT RS13715
gene id: 580332:SLIT_RS13715
uniprot id: D5CPH6
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

580332:SLIT RS03515
gene id: 580332:SLIT_RS03515
uniprot id: D5CNN3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

580332:SLIT RS04920
gene id: 580332:SLIT_RS04920
uniprot id: D5CQ59
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

580332:SLIT RS06890
gene id: 580332:SLIT_RS06890
uniprot id: D5CRN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

580332:SLIT RS08255
gene id: 580332:SLIT_RS08255
uniprot id: D5CSE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

580332:SLIT RS14720
gene id: 580332:SLIT_RS14720
uniprot id: D5CQF4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

580332:SLIT RS09850
gene id: 580332:SLIT_RS09850
uniprot id: D5CTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

580332:SLIT RS05205
gene id: 580332:SLIT_RS05205
uniprot id: D5CQP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

580332:SLIT RS01435
gene id: 580332:SLIT_RS01435
uniprot id: D5CLE6
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

580332:SLIT RS06270
gene id: 580332:SLIT_RS06270
uniprot id: D5CRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

580332:SLIT RS02105
gene id: 580332:SLIT_RS02105
uniprot id: D5CM50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

580332:SLIT RS00625
gene id: 580332:SLIT_RS00625
uniprot id: D5CU33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

580332:SLIT RS12185
gene id: 580332:SLIT_RS12185
uniprot id: D5CMJ0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

580332:SLIT RS01250
gene id: 580332:SLIT_RS01250
uniprot id: D5CLA9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

580332:SLIT RS10535
gene id: 580332:SLIT_RS10535
uniprot id: D5CU24
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS10890
gene id: 580332:SLIT_RS10890
uniprot id: D5CUL8
names: Similarity
messages: Belongs to the UPF0047 family.

580332:SLIT RS12635
gene id: 580332:SLIT_RS12635
uniprot id: D5CN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

580332:SLIT RS08980
gene id: 580332:SLIT_RS08980
uniprot id: D5CSU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

580332:SLIT RS04370
gene id: 580332:SLIT_RS04370
uniprot id: D5CPH0
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS03835
gene id: 580332:SLIT_RS03835
uniprot id: D5CP64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

580332:SLIT RS14065
gene id: 580332:SLIT_RS14065
uniprot id: D5CPP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

580332:SLIT RS08060
gene id: 580332:SLIT_RS08060
uniprot id: D5CSA8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

580332:SLIT RS09400
gene id: 580332:SLIT_RS09400
uniprot id: D5CT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

580332:SLIT RS04310
gene id: 580332:SLIT_RS04310
uniprot id: D5CPF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS05310
gene id: 580332:SLIT_RS05310
uniprot id: D5CQR5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

580332:SLIT RS10550
gene id: 580332:SLIT_RS10550
uniprot id: D5CU27
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

580332:SLIT RS14890
gene id: 580332:SLIT_RS14890
uniprot id: D5CQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

580332:SLIT RS08960
gene id: 580332:SLIT_RS08960
uniprot id: D5CST6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS10160
gene id: 580332:SLIT_RS10160
uniprot id: D5CTU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

580332:SLIT RS10295
gene id: 580332:SLIT_RS10295
uniprot id: D5CTX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580332:SLIT RS11280
gene id: 580332:SLIT_RS11280
uniprot id: D5CLP2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

580332:SLIT RS04805
gene id: 580332:SLIT_RS04805
uniprot id: D5CQ36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

580332:SLIT RS02135
gene id: 580332:SLIT_RS02135
uniprot id: D5CM56
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS14255
gene id: 580332:SLIT_RS14255
uniprot id: D5CPT6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

580332:SLIT RS11735
gene id: 580332:SLIT_RS11735
uniprot id: D5CLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

580332:SLIT RS11130
gene id: 580332:SLIT_RS11130
uniprot id: D5CUR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS02225
gene id: 580332:SLIT_RS02225
uniprot id: D5CM74
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

580332:SLIT RS02480
gene id: 580332:SLIT_RS02480
uniprot id: D5CMQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

580332:SLIT RS13335
gene id: 580332:SLIT_RS13335
uniprot id: D5CNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

580332:SLIT RS06300
gene id: 580332:SLIT_RS06300
uniprot id: D5CRB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

580332:SLIT RS06435
gene id: 580332:SLIT_RS06435
uniprot id: D5CRE4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

580332:SLIT RS08360
gene id: 580332:SLIT_RS08360
uniprot id: D5CSG9
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

580332:SLIT RS04510
gene id: 580332:SLIT_RS04510
uniprot id: D5CPX7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

580332:SLIT RS12420
gene id: 580332:SLIT_RS12420
uniprot id: D5CMN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

580332:SLIT RS13610
gene id: 580332:SLIT_RS13610
uniprot id: D5CP30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

580332:SLIT RS02545
gene id: 580332:SLIT_RS02545
uniprot id: D5CMR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

580332:SLIT RS01700
gene id: 580332:SLIT_RS01700
uniprot id: D5CLK0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

580332:SLIT RS02470
gene id: 580332:SLIT_RS02470
uniprot id: D5CMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

580332:SLIT RS02960
gene id: 580332:SLIT_RS02960
uniprot id: D5CMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS14285
gene id: 580332:SLIT_RS14285
uniprot id: D5CPU2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

580332:SLIT RS00115
gene id: 580332:SLIT_RS00115
uniprot id: D5CTF8
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

580332:SLIT RS09165
gene id: 580332:SLIT_RS09165
uniprot id: D5CSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS04870
gene id: 580332:SLIT_RS04870
uniprot id: D5CQ49
names: Similarity
messages: Belongs to the barstar family.

580332:SLIT RS08310
gene id: 580332:SLIT_RS08310
uniprot id: D5CSF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

580332:SLIT RS03950
gene id: 580332:SLIT_RS03950
uniprot id: D5CP87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

580332:SLIT RS01425
gene id: 580332:SLIT_RS01425
uniprot id: D5CLE4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

580332:SLIT RS10620
gene id: 580332:SLIT_RS10620
uniprot id: D5CUG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

580332:SLIT RS08970
gene id: 580332:SLIT_RS08970
uniprot id: D5CST8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

580332:SLIT RS14545
gene id: 580332:SLIT_RS14545
uniprot id: D5CQB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

580332:SLIT RS05165
gene id: 580332:SLIT_RS05165
uniprot id: D5CQN6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

580332:SLIT RS03055
gene id: 580332:SLIT_RS03055
uniprot id: D5CN18
names: Similarity
messages: Belongs to the type III secretion exporter family.

580332:SLIT RS09020
gene id: 580332:SLIT_RS09020
uniprot id: D5CSU6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

580332:SLIT RS07680
gene id: 580332:SLIT_RS07680
uniprot id: D5CS39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

580332:SLIT RS11725
gene id: 580332:SLIT_RS11725
uniprot id: D5CLX8
names: Similarity
messages: Belongs to the UPF0225 family.

580332:SLIT RS15305
gene id: 580332:SLIT_RS15305
uniprot id: D5CUK1
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS06725
gene id: 580332:SLIT_RS06725
uniprot id: D5CRK1
names: Similarity
messages: Belongs to the pirin family.

580332:SLIT RS07055
gene id: 580332:SLIT_RS07055
uniprot id: D5CRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

580332:SLIT RS05365
gene id: 580332:SLIT_RS05365
uniprot id: D5CQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS11010
gene id: 580332:SLIT_RS11010
uniprot id: D5CUP5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

580332:SLIT RS02825
gene id: 580332:SLIT_RS02825
uniprot id: D5CMX1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

580332:SLIT RS12690
gene id: 580332:SLIT_RS12690
uniprot id: D5CN69
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

580332:SLIT RS00350
gene id: 580332:SLIT_RS00350
uniprot id: D5CTK5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580332:SLIT RS02065
gene id: 580332:SLIT_RS02065
uniprot id: D5CM41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

580332:SLIT RS07405
gene id: 580332:SLIT_RS07405
uniprot id: D5CRZ2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

580332:SLIT RS09220
gene id: 580332:SLIT_RS09220
uniprot id: D5CSY5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

580332:SLIT RS11810
gene id: 580332:SLIT_RS11810
uniprot id: D5CLZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

580332:SLIT RS04630
gene id: 580332:SLIT_RS04630
uniprot id: D5CQ01
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

580332:SLIT RS10455
gene id: 580332:SLIT_RS10455
uniprot id: D5CU08
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS08285
gene id: 580332:SLIT_RS08285
uniprot id: D5CSF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

580332:SLIT RS07035
gene id: 580332:SLIT_RS07035
uniprot id: D5CRR7
names: Similarity
messages: Belongs to the YfgM family.

580332:SLIT RS10485
gene id: 580332:SLIT_RS10485
uniprot id: D5CU14
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

580332:SLIT RS03765
gene id: 580332:SLIT_RS03765
uniprot id: D5CP51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

580332:SLIT RS07515
gene id: 580332:SLIT_RS07515
uniprot id: D5CS09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

580332:SLIT RS02190
gene id: 580332:SLIT_RS02190
uniprot id: D5CM67
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

580332:SLIT RS05815
gene id: 580332:SLIT_RS05815
uniprot id: D5CR20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

580332:SLIT RS14240
gene id: 580332:SLIT_RS14240
uniprot id: D5CPT2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS13255
gene id: 580332:SLIT_RS13255
uniprot id: D5CNV9
names: Cofactor
names: Similarity
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

580332:SLIT RS08660
gene id: 580332:SLIT_RS08660
uniprot id: D5CSM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

580332:SLIT RS03790
gene id: 580332:SLIT_RS03790
uniprot id: D5CP55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

580332:SLIT RS02445
gene id: 580332:SLIT_RS02445
uniprot id: D5CMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS12020
gene id: 580332:SLIT_RS12020
uniprot id: D5CMF8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

580332:SLIT RS00010
gene id: 580332:SLIT_RS00010
uniprot id: D5CTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

580332:SLIT RS11275
gene id: 580332:SLIT_RS11275
uniprot id: D5CLP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS03960
gene id: 580332:SLIT_RS03960
uniprot id: D5CP89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

580332:SLIT RS05190
gene id: 580332:SLIT_RS05190
uniprot id: D5CQP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

580332:SLIT RS15770
gene id: 580332:SLIT_RS15770
uniprot id: D5CMA1
names: Similarity
messages: Belongs to the frataxin family.

580332:SLIT RS12345
gene id: 580332:SLIT_RS12345
uniprot id: D5CMM2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

580332:SLIT RS10510
gene id: 580332:SLIT_RS10510
uniprot id: D5CU19
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

580332:SLIT RS10390
gene id: 580332:SLIT_RS10390
uniprot id: D5CTZ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

580332:SLIT RS00025
gene id: 580332:SLIT_RS00025
uniprot id: D5CTE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

580332:SLIT RS08400
gene id: 580332:SLIT_RS08400
uniprot id: D5CSH7
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS08135
gene id: 580332:SLIT_RS08135
uniprot id: D5CSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS10650
gene id: 580332:SLIT_RS10650
uniprot id: D5CUH2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

580332:SLIT RS03600
gene id: 580332:SLIT_RS03600
uniprot id: D5CNP9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

580332:SLIT RS01955
gene id: 580332:SLIT_RS01955
uniprot id: D5CM20
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

580332:SLIT RS14260
gene id: 580332:SLIT_RS14260
uniprot id: D5CPT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

580332:SLIT RS01040
gene id: 580332:SLIT_RS01040
uniprot id: D5CUB6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

580332:SLIT RS02715
gene id: 580332:SLIT_RS02715
uniprot id: D5CMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

580332:SLIT RS07045
gene id: 580332:SLIT_RS07045
uniprot id: D5CRR9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

580332:SLIT RS09975
gene id: 580332:SLIT_RS09975
uniprot id: D5CTR2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

580332:SLIT RS12565
gene id: 580332:SLIT_RS12565
uniprot id: D5CN43
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS14885
gene id: 580332:SLIT_RS14885
uniprot id: D5CQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

580332:SLIT RS03810
gene id: 580332:SLIT_RS03810
uniprot id: D5CP59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

580332:SLIT RS07365
gene id: 580332:SLIT_RS07365
uniprot id: D5CRY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

580332:SLIT RS05230
gene id: 580332:SLIT_RS05230
uniprot id: D5CQP9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

580332:SLIT RS10175
gene id: 580332:SLIT_RS10175
uniprot id: D5CTV2
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS04040
gene id: 580332:SLIT_RS04040
uniprot id: D5CPA5
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

580332:SLIT RS01710
gene id: 580332:SLIT_RS01710
uniprot id: D5CLK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

580332:SLIT RS11530
gene id: 580332:SLIT_RS11530
uniprot id: D5CLT9
names: Similarity
messages: Belongs to the peptidase S11 family.

580332:SLIT RS01960
gene id: 580332:SLIT_RS01960
uniprot id: D5CM21
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

580332:SLIT RS08190
gene id: 580332:SLIT_RS08190
uniprot id: D5CSD5
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

580332:SLIT RS11235
gene id: 580332:SLIT_RS11235
uniprot id: D5CLN3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

580332:SLIT RS04025
gene id: 580332:SLIT_RS04025
uniprot id: D5CPA2
names: Similarity
messages: Belongs to the HesB/IscA family.

580332:SLIT RS05405
gene id: 580332:SLIT_RS05405
uniprot id: D5CQT3
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS11110
gene id: 580332:SLIT_RS11110
uniprot id: D5CUR5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

580332:SLIT RS09060
gene id: 580332:SLIT_RS09060
uniprot id: D5CSV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

580332:SLIT RS04755
gene id: 580332:SLIT_RS04755
uniprot id: D5CQ27
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

580332:SLIT RS05615
gene id: 580332:SLIT_RS05615
uniprot id: D5CQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

580332:SLIT RS13595
gene id: 580332:SLIT_RS13595
uniprot id: D5CP27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

580332:SLIT RS01455
gene id: 580332:SLIT_RS01455
uniprot id: D5CLF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS09200
gene id: 580332:SLIT_RS09200
uniprot id: D5CSY1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

580332:SLIT RS14785
gene id: 580332:SLIT_RS14785
uniprot id: D5CQG8
names: Similarity
messages: Belongs to the UPF0102 family.

580332:SLIT RS07915
gene id: 580332:SLIT_RS07915
uniprot id: D5CS81
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

580332:SLIT RS01850
gene id: 580332:SLIT_RS01850
uniprot id: D5CLM4
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS13145
gene id: 580332:SLIT_RS13145
uniprot id: D5CNT5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

580332:SLIT RS03845
gene id: 580332:SLIT_RS03845
uniprot id: D5CP66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

580332:SLIT RS13865
gene id: 580332:SLIT_RS13865
uniprot id: D5CPK6
names: Similarity
messages: Belongs to the acylphosphatase family.

580332:SLIT RS12585
gene id: 580332:SLIT_RS12585
uniprot id: D5CN47
names: Similarity
messages: Belongs to the peptidase M17 family.

580332:SLIT RS10750
gene id: 580332:SLIT_RS10750
uniprot id: D5CUJ2
names: Similarity
messages: Belongs to the CapA family.

580332:SLIT RS02595
gene id: 580332:SLIT_RS02595
uniprot id: D5CMS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

580332:SLIT RS13370
gene id: 580332:SLIT_RS13370
uniprot id: D5CNY2
names: Similarity
messages: Belongs to the hemerythrin family.

580332:SLIT RS14900
gene id: 580332:SLIT_RS14900
uniprot id: D5CQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

580332:SLIT RS10355
gene id: 580332:SLIT_RS10355
uniprot id: D5CTY9
names: Similarity
messages: Belongs to the GSP E family.

580332:SLIT RS01595
gene id: 580332:SLIT_RS01595
uniprot id: D5CLH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

580332:SLIT RS06930
gene id: 580332:SLIT_RS06930
uniprot id: D5CRP4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

580332:SLIT RS12090
gene id: 580332:SLIT_RS12090
uniprot id: D5CMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS00210
gene id: 580332:SLIT_RS00210
uniprot id: D5CTH6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS04190
gene id: 580332:SLIT_RS04190
uniprot id: D5CPD6
names: Similarity
messages: Belongs to the NifX/NifY family.

580332:SLIT RS00870
gene id: 580332:SLIT_RS00870
uniprot id: D5CU81
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

580332:SLIT RS14490
gene id: 580332:SLIT_RS14490
uniprot id: D5CQA7
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

580332:SLIT RS06360
gene id: 580332:SLIT_RS06360
uniprot id: D5CRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

580332:SLIT RS14875
gene id: 580332:SLIT_RS14875
uniprot id: D5CQI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

580332:SLIT RS06935
gene id: 580332:SLIT_RS06935
uniprot id: D5CRP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

580332:SLIT RS08180
gene id: 580332:SLIT_RS08180
uniprot id: D5CSD3
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS05240
gene id: 580332:SLIT_RS05240
uniprot id: D5CQQ1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

580332:SLIT RS08990
gene id: 580332:SLIT_RS08990
uniprot id: D5CSU2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

580332:SLIT RS05450
gene id: 580332:SLIT_RS05450
uniprot id: D5CQU2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.
messages: Belongs to the type-I restriction system S methylase family.

580332:SLIT RS10575
gene id: 580332:SLIT_RS10575
uniprot id: D5CUF7
names: Similarity
messages: Belongs to the TrpF family.

580332:SLIT RS05395
gene id: 580332:SLIT_RS05395
uniprot id: D5CQT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS01745
gene id: 580332:SLIT_RS01745
uniprot id: D5CLK4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

580332:SLIT RS02550
gene id: 580332:SLIT_RS02550
uniprot id: D5CMR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

580332:SLIT RS05355
gene id: 580332:SLIT_RS05355
uniprot id: D5CQS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

580332:SLIT RS13410
gene id: 580332:SLIT_RS13410
uniprot id: D5CNY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS04865
gene id: 580332:SLIT_RS04865
uniprot id: D5CQ48
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

580332:SLIT RS06335
gene id: 580332:SLIT_RS06335
uniprot id: D5CRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

580332:SLIT RS02450
gene id: 580332:SLIT_RS02450
uniprot id: D5CMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS13860
gene id: 580332:SLIT_RS13860
uniprot id: D5CPK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

580332:SLIT RS08560
gene id: 580332:SLIT_RS08560
uniprot id: D5CSK8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

580332:SLIT RS14245
gene id: 580332:SLIT_RS14245
uniprot id: D5CPT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

580332:SLIT RS12330
gene id: 580332:SLIT_RS12330
uniprot id: D5CML9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS12095
gene id: 580332:SLIT_RS12095
uniprot id: D5CMH3
names: Similarity
messages: Belongs to the HypE family.

580332:SLIT RS13490
gene id: 580332:SLIT_RS13490
uniprot id: D5CP05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

580332:SLIT RS09050
gene id: 580332:SLIT_RS09050
uniprot id: D5CSV2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

580332:SLIT RS08245
gene id: 580332:SLIT_RS08245
uniprot id: D5CSE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS03145
gene id: 580332:SLIT_RS03145
uniprot id: D5CNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

580332:SLIT RS09935
gene id: 580332:SLIT_RS09935
uniprot id: D5CTD0
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS11035
gene id: 580332:SLIT_RS11035
uniprot id: D5CUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

580332:SLIT RS07040
gene id: 580332:SLIT_RS07040
uniprot id: D5CRR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

580332:SLIT RS12070
gene id: 580332:SLIT_RS12070
uniprot id: D5CMG8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

580332:SLIT RS07895
gene id: 580332:SLIT_RS07895
uniprot id: D5CS77
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS00330
gene id: 580332:SLIT_RS00330
uniprot id: D5CTK1
names: Similarity
messages: Belongs to the P(II) protein family.

580332:SLIT RS08375
gene id: 580332:SLIT_RS08375
uniprot id: D5CSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

580332:SLIT RS11595
gene id: 580332:SLIT_RS11595
uniprot id: D5CLV2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

580332:SLIT RS11850
gene id: 580332:SLIT_RS11850
uniprot id: D5CMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

580332:SLIT RS02580
gene id: 580332:SLIT_RS02580
uniprot id: D5CMS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

580332:SLIT RS14845
gene id: 580332:SLIT_RS14845
uniprot id: D5CQI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS04820
gene id: 580332:SLIT_RS04820
uniprot id: D5CQ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

580332:SLIT RS00255
gene id: 580332:SLIT_RS00255
uniprot id: D5CTI5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

580332:SLIT RS06755
gene id: 580332:SLIT_RS06755
uniprot id: D5CRK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

580332:SLIT RS02475
gene id: 580332:SLIT_RS02475
uniprot id: D5CMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

580332:SLIT RS12745
gene id: 580332:SLIT_RS12745
uniprot id: D5CN80
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

580332:SLIT RS00935
gene id: 580332:SLIT_RS00935
uniprot id: D5CU94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

580332:SLIT RS07260
gene id: 580332:SLIT_RS07260
uniprot id: D5CRW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

580332:SLIT RS12590
gene id: 580332:SLIT_RS12590
uniprot id: D5CN48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS11075
gene id: 580332:SLIT_RS11075
uniprot id: D5CUQ8
names: Similarity
messages: Belongs to the threonine synthase family.

580332:SLIT RS02740
gene id: 580332:SLIT_RS02740
uniprot id: D5CMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

580332:SLIT RS01705
gene id: 580332:SLIT_RS01705
uniprot id: D5CLK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

580332:SLIT RS10375
gene id: 580332:SLIT_RS10375
uniprot id: D5CTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

580332:SLIT RS03530
gene id: 580332:SLIT_RS03530
uniprot id: D5CNN6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

580332:SLIT RS15285
gene id: 580332:SLIT_RS15285
uniprot id: D5CTR9
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS00055
gene id: 580332:SLIT_RS00055
uniprot id: D5CTE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

580332:SLIT RS14435
gene id: 580332:SLIT_RS14435
uniprot id: D5CQ96
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS05830
gene id: 580332:SLIT_RS05830
uniprot id: D5CR23
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

580332:SLIT RS03455
gene id: 580332:SLIT_RS03455
uniprot id: D5CNM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS08165
gene id: 580332:SLIT_RS08165
uniprot id: D5CSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

580332:SLIT RS12390
gene id: 580332:SLIT_RS12390
uniprot id: D5CMN2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

580332:SLIT RS06810
gene id: 580332:SLIT_RS06810
uniprot id: D5CRL9
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS07255
gene id: 580332:SLIT_RS07255
uniprot id: D5CRW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

580332:SLIT RS04905
gene id: 580332:SLIT_RS04905
uniprot id: D5CQ56
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS06225
gene id: 580332:SLIT_RS06225
uniprot id: D5CRA1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

580332:SLIT RS02700
gene id: 580332:SLIT_RS02700
uniprot id: D5CMU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

580332:SLIT RS10680
gene id: 580332:SLIT_RS10680
uniprot id: D5CUH8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

580332:SLIT RS09415
gene id: 580332:SLIT_RS09415
uniprot id: D5CT25
names: Similarity
messages: Belongs to the phosphohexose mutase family.

580332:SLIT RS07010
gene id: 580332:SLIT_RS07010
uniprot id: D5CRR2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

580332:SLIT RS11015
gene id: 580332:SLIT_RS11015
uniprot id: D5CUP6
names: Similarity
messages: Belongs to the thioredoxin family.

580332:SLIT RS10000
gene id: 580332:SLIT_RS10000
uniprot id: D5CTR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

580332:SLIT RS11760
gene id: 580332:SLIT_RS11760
uniprot id: D5CLY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

580332:SLIT RS12110
gene id: 580332:SLIT_RS12110
uniprot id: D5CMH5
names: Similarity
messages: Belongs to the HupF/HypC family.

580332:SLIT RS02305
gene id: 580332:SLIT_RS02305
uniprot id: D5CM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

580332:SLIT RS13050
gene id: 580332:SLIT_RS13050
uniprot id: D5CNE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

580332:SLIT RS16175
gene id: 580332:SLIT_RS16175
uniprot id: D5CMV7
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

580332:SLIT RS08065
gene id: 580332:SLIT_RS08065
uniprot id: D5CSA9
names: Similarity
messages: Belongs to the peptidase A31 family.

580332:SLIT RS14425
gene id: 580332:SLIT_RS14425
uniprot id: D5CQ94
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

580332:SLIT RS08230
gene id: 580332:SLIT_RS08230
uniprot id: D5CSE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

580332:SLIT RS01085
gene id: 580332:SLIT_RS01085
uniprot id: D5CUC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS01355
gene id: 580332:SLIT_RS01355
uniprot id: D5CLD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

580332:SLIT RS00205
gene id: 580332:SLIT_RS00205
uniprot id: D5CTH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

580332:SLIT RS03800
gene id: 580332:SLIT_RS03800
uniprot id: D5CP57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

580332:SLIT RS01350
gene id: 580332:SLIT_RS01350
uniprot id: D5CLC9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

580332:SLIT RS05340
gene id: 580332:SLIT_RS05340
uniprot id: D5CQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

580332:SLIT RS14230
gene id: 580332:SLIT_RS14230
uniprot id: D5CPT0
names: Similarity
messages: Belongs to the CutA family.

580332:SLIT RS06115
gene id: 580332:SLIT_RS06115
uniprot id: D5CR79
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

580332:SLIT RS00225
gene id: 580332:SLIT_RS00225
uniprot id: D5CTH9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

580332:SLIT RS10665
gene id: 580332:SLIT_RS10665
uniprot id: D5CUH5
names: Subcellular Location Annotation
messages: Membrane

580332:SLIT RS00700
gene id: 580332:SLIT_RS00700
uniprot id: D5CU48
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

580332:SLIT RS09160
gene id: 580332:SLIT_RS09160
uniprot id: D5CSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

580332:SLIT RS12750
gene id: 580332:SLIT_RS12750
uniprot id: D5CN81
names: Similarity
messages: Belongs to the V-ATPase E subunit family.