578455:THITE 2118463
gene id: 578455:THITE_2118463
uniprot id: G2RA16
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

578455:THITE 2123588
gene id: 578455:THITE_2123588
uniprot id: G2RHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

578455:THITE 2118104
gene id: 578455:THITE_2118104
uniprot id: G2R6X6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2118057
gene id: 578455:THITE_2118057
uniprot id: G2R6U0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120064
gene id: 578455:THITE_2120064
uniprot id: G2R9I7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

578455:THITE 2111492
gene id: 578455:THITE_2111492
uniprot id: G2R2P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

578455:THITE 120949
gene id: 578455:THITE_120949
uniprot id: G2QXB9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118888
gene id: 578455:THITE_2118888
uniprot id: G2RB08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.

578455:THITE 2124103
gene id: 578455:THITE_2124103
uniprot id: G2RIA8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2065770
gene id: 578455:THITE_2065770
uniprot id: G2R3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

578455:THITE 2116556
gene id: 578455:THITE_2116556
uniprot id: G2R6Q0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.

578455:THITE 2106628
gene id: 578455:THITE_2106628
uniprot id: G2QQZ8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113238
gene id: 578455:THITE_2113238
uniprot id: G2R216
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

578455:THITE 2112358
gene id: 578455:THITE_2112358
uniprot id: G2QYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

578455:THITE 2119567
gene id: 578455:THITE_2119567
uniprot id: G2RBY8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

578455:THITE 2117325
gene id: 578455:THITE_2117325
uniprot id: G2R7W8
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

578455:THITE 124439
gene id: 578455:THITE_124439
uniprot id: G2RI06
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2092104
gene id: 578455:THITE_2092104
uniprot id: G2RCG5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

578455:THITE 2064529
gene id: 578455:THITE_2064529
uniprot id: G2R2R6
names: Similarity
messages: Belongs to the CIA30 family.

578455:THITE 2121762
gene id: 578455:THITE_2121762
uniprot id: G2RF96
names: Function
names: Similarity
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.

578455:THITE 2144820
gene id: 578455:THITE_2144820
uniprot id: G2R5H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 2171649
gene id: 578455:THITE_2171649
uniprot id: G2RIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2118622
gene id: 578455:THITE_2118622
uniprot id: G2RAD5
names: Function
names: Similarity
messages: Belongs to the FYV10 family.
messages: Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.

578455:THITE 2114867
gene id: 578455:THITE_2114867
uniprot id: G2R259
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

578455:THITE 2116699
gene id: 578455:THITE_2116699
uniprot id: G2R706
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

578455:THITE 2145653
gene id: 578455:THITE_2145653
uniprot id: G2R6U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2116251
gene id: 578455:THITE_2116251
uniprot id: G2R165
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2122426
gene id: 578455:THITE_2122426
uniprot id: G2RD33
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112931
gene id: 578455:THITE_2112931
uniprot id: G2R0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2107535
gene id: 578455:THITE_2107535
uniprot id: G2QU85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2106139
gene id: 578455:THITE_2106139
uniprot id: G2QW46
names: Similarity
messages: Belongs to the TAF11 family.

578455:THITE 2116429
gene id: 578455:THITE_2116429
uniprot id: G2R5V0
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2107255
gene id: 578455:THITE_2107255
uniprot id: G2QTC2
names: Function
names: Similarity
messages: ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.

578455:THITE 18232
gene id: 578455:THITE_18232
uniprot id: G2RH54
names: Similarity
messages: Belongs to the MGMT family.

578455:THITE 2120923
gene id: 578455:THITE_2120923
uniprot id: G2RE26
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

578455:THITE 43879
gene id: 578455:THITE_43879
uniprot id: G2RBB3
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2124496
gene id: 578455:THITE_2124496
uniprot id: G2RFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

578455:THITE 2117485
gene id: 578455:THITE_2117485
uniprot id: G2R852
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

578455:THITE 2115571
gene id: 578455:THITE_2115571
uniprot id: G2R4X3
names: Similarity
messages: Belongs to the asteroid family.

578455:THITE 2108275
gene id: 578455:THITE_2108275
uniprot id: G2QQQ4
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

578455:THITE 2112526
gene id: 578455:THITE_2112526
uniprot id: G2QZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

578455:THITE 2144096
gene id: 578455:THITE_2144096
uniprot id: G2R1N0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118435
gene id: 578455:THITE_2118435
uniprot id: G2RA05
names: Similarity
messages: Belongs to the SDO1/SBDS family.

578455:THITE 2111516
gene id: 578455:THITE_2111516
uniprot id: G2R2Q8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 125023
gene id: 578455:THITE_125023
uniprot id: G2R5N0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117287
gene id: 578455:THITE_2117287
uniprot id: G2R7U9
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

578455:THITE 2051998
gene id: 578455:THITE_2051998
uniprot id: G2R8B2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2069122
gene id: 578455:THITE_2069122
uniprot id: G2R9W0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

578455:THITE 2106790
gene id: 578455:THITE_2106790
uniprot id: G2QRI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

578455:THITE 2106775
gene id: 578455:THITE_2106775
uniprot id: G2QRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

578455:THITE 2171584
gene id: 578455:THITE_2171584
uniprot id: G2RHT5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

578455:THITE 2055528
gene id: 578455:THITE_2055528
uniprot id: G2RCZ0
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

578455:THITE 2111714
gene id: 578455:THITE_2111714
uniprot id: G2R387
names: Similarity
messages: Belongs to the PPC synthetase family.

578455:THITE 2109948
gene id: 578455:THITE_2109948
uniprot id: G2QQW9
names: Similarity
messages: Belongs to the FGGY kinase family.

578455:THITE 2045851
gene id: 578455:THITE_2045851
uniprot id: G2R493
names: Similarity
messages: Belongs to the peptidase S33 family.

578455:THITE 2114513
gene id: 578455:THITE_2114513
uniprot id: G2R045
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112447
gene id: 578455:THITE_2112447
uniprot id: G2QZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

578455:THITE 2116061
gene id: 578455:THITE_2116061
uniprot id: G2QZT3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

578455:THITE 2156244
gene id: 578455:THITE_2156244
uniprot id: G2RFG2
names: Function
names: Similarity
messages: Belongs to the DPH4 family.
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

578455:THITE 2108273
gene id: 578455:THITE_2108273
uniprot id: G2QQQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

578455:THITE 2096446
gene id: 578455:THITE_2096446
uniprot id: G2RAB6
names: Similarity
messages: Belongs to the peptidase M28 family.

578455:THITE 2114534
gene id: 578455:THITE_2114534
uniprot id: G2R056
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

578455:THITE 2115691
gene id: 578455:THITE_2115691
uniprot id: G2R5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

578455:THITE 2119604
gene id: 578455:THITE_2119604
uniprot id: G2RC07
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

578455:THITE 2120844
gene id: 578455:THITE_2120844
uniprot id: G2RDU0
names: Similarity
messages: Belongs to the threonine aldolase family.

578455:THITE 110529
gene id: 578455:THITE_110529
uniprot id: G2R1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSH4 family.
messages: Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.
messages: Endosome membrane
messages: Membrane
messages: Vacuole membrane

578455:THITE 2144922
gene id: 578455:THITE_2144922
uniprot id: G2R6C2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106294
gene id: 578455:THITE_2106294
uniprot id: G2QX64
names: Similarity
messages: Belongs to the ADIP family.

578455:THITE 2123400
gene id: 578455:THITE_2123400
uniprot id: G2RHB7
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2128403
gene id: 578455:THITE_2128403
uniprot id: G2QZ90
names: Subcellular Location Annotation
messages: Secreted

578455:THITE 2108975
gene id: 578455:THITE_2108975
uniprot id: G2QT24
names: Similarity
messages: Belongs to the peptidase S10 family.

578455:THITE 2155092
gene id: 578455:THITE_2155092
uniprot id: G2R7J5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106972
gene id: 578455:THITE_2106972
uniprot id: G2QSC8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

578455:THITE 2116324
gene id: 578455:THITE_2116324
uniprot id: G2R5F6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2118733
gene id: 578455:THITE_2118733
uniprot id: G2RAN9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

578455:THITE 117213
gene id: 578455:THITE_117213
uniprot id: G2R6X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 73720
gene id: 578455:THITE_73720
uniprot id: G2RCT8
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

578455:THITE 2120373
gene id: 578455:THITE_2120373
uniprot id: G2RAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Secreted

578455:THITE 121411
gene id: 578455:THITE_121411
uniprot id: G2R8T8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 71681
gene id: 578455:THITE_71681
uniprot id: G2RBU7
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

578455:THITE 2121411
gene id: 578455:THITE_2121411
uniprot id: G2REW2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

578455:THITE 2155431
gene id: 578455:THITE_2155431
uniprot id: G2RA17
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

578455:THITE 2117084
gene id: 578455:THITE_2117084
uniprot id: G2R7K2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111508
gene id: 578455:THITE_2111508
uniprot id: G2R2Q4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

578455:THITE 58996
gene id: 578455:THITE_58996
uniprot id: G2QT33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

578455:THITE 2119764
gene id: 578455:THITE_2119764
uniprot id: G2RC78
names: Function
names: Similarity
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.

578455:THITE 2058212
gene id: 578455:THITE_2058212
uniprot id: G2RGY9
names: Similarity
messages: Belongs to the threonine synthase family.

578455:THITE 2086916
gene id: 578455:THITE_2086916
uniprot id: G2QZ03
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

578455:THITE 2106957
gene id: 578455:THITE_2106957
uniprot id: G2QS11
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 2107188
gene id: 578455:THITE_2107188
uniprot id: G2QT95
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 117302
gene id: 578455:THITE_117302
uniprot id: G2R6I0
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 131345
gene id: 578455:THITE_131345
uniprot id: G2QS70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

578455:THITE 2124223
gene id: 578455:THITE_2124223
uniprot id: G2RIF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the dehydroquinate synthase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

578455:THITE 36710
gene id: 578455:THITE_36710
uniprot id: G2R3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

578455:THITE 2107678
gene id: 578455:THITE_2107678
uniprot id: G2QUP8
names: Similarity
messages: Belongs to the GET4 family.

578455:THITE 2106701
gene id: 578455:THITE_2106701
uniprot id: G2QR35
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2121465
gene id: 578455:THITE_2121465
uniprot id: G2REY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

578455:THITE 2146851
gene id: 578455:THITE_2146851
uniprot id: G2RDI2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.

578455:THITE 2123297
gene id: 578455:THITE_2123297
uniprot id: G2RH60
names: Similarity
messages: Belongs to the SKP1 family.

578455:THITE 37833
gene id: 578455:THITE_37833
uniprot id: G2R016
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

578455:THITE 2115897
gene id: 578455:THITE_2115897
uniprot id: G2QYW1
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

578455:THITE 2109539
gene id: 578455:THITE_2109539
uniprot id: G2QWF2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2121528
gene id: 578455:THITE_2121528
uniprot id: G2RF14
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117842
gene id: 578455:THITE_2117842
uniprot id: G2R5Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

578455:THITE 2094955
gene id: 578455:THITE_2094955
uniprot id: G2QYL2
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

578455:THITE 2108244
gene id: 578455:THITE_2108244
uniprot id: G2QQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

578455:THITE 48349
gene id: 578455:THITE_48349
uniprot id: G2QX14
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2115977
gene id: 578455:THITE_2115977
uniprot id: G2QZB8
names: Similarity
messages: Belongs to the phospholipase D family.

578455:THITE 2118563
gene id: 578455:THITE_2118563
uniprot id: G2RAA9
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

578455:THITE 2111027
gene id: 578455:THITE_2111027
uniprot id: G2QWG2
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

578455:THITE 2052360
gene id: 578455:THITE_2052360
uniprot id: G2RAW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

578455:THITE 2124019
gene id: 578455:THITE_2124019
uniprot id: G2RI67
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2108317
gene id: 578455:THITE_2108317
uniprot id: G2QQS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2106808
gene id: 578455:THITE_2106808
uniprot id: G2QRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

578455:THITE 2123222
gene id: 578455:THITE_2123222
uniprot id: G2RH05
names: Similarity
messages: Belongs to the TCP11 family.

578455:THITE 2087275
gene id: 578455:THITE_2087275
uniprot id: G2R219
names: Similarity
messages: Belongs to the APS kinase family.

578455:THITE 2106865
gene id: 578455:THITE_2106865
uniprot id: G2QRW7
names: Similarity
messages: Belongs to the activator 1 small subunits family.

578455:THITE 2114229
gene id: 578455:THITE_2114229
uniprot id: G2QYS0
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2123181
gene id: 578455:THITE_2123181
uniprot id: G2RGY8
names: Similarity
messages: Belongs to the PPP phosphatase family.

578455:THITE 2085319
gene id: 578455:THITE_2085319
uniprot id: G2QVC1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2107984
gene id: 578455:THITE_2107984
uniprot id: G2QWU8
names: Similarity
messages: Belongs to the Cyclase 1 superfamily.

578455:THITE 2116275
gene id: 578455:THITE_2116275
uniprot id: G2R176
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

578455:THITE 2107888
gene id: 578455:THITE_2107888
uniprot id: G2QW77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

578455:THITE 2114877
gene id: 578455:THITE_2114877
uniprot id: G2R265
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121047
gene id: 578455:THITE_2121047
uniprot id: G2REC7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2110191
gene id: 578455:THITE_2110191
uniprot id: G2QRV4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 2131928
gene id: 578455:THITE_2131928
uniprot id: G2RFH3
names: Similarity
messages: Belongs to the tyrosinase family.

578455:THITE 2115356
gene id: 578455:THITE_2115356
uniprot id: G2R416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

578455:THITE 2110732
gene id: 578455:THITE_2110732
uniprot id: G2QU55
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

578455:THITE 2122425
gene id: 578455:THITE_2122425
uniprot id: G2RD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

578455:THITE 2123728
gene id: 578455:THITE_2123728
uniprot id: G2RHU6
names: Similarity
messages: Belongs to the CHS7 family.

578455:THITE 2115572
gene id: 578455:THITE_2115572
uniprot id: G2R4X4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

578455:THITE 2111745
gene id: 578455:THITE_2111745
uniprot id: G2R3K6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

578455:THITE 2037471
gene id: 578455:THITE_2037471
uniprot id: G2QS02
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

578455:THITE 2115656
gene id: 578455:THITE_2115656
uniprot id: G2R5B8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2124388
gene id: 578455:THITE_2124388
uniprot id: G2RFS5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117702
gene id: 578455:THITE_2117702
uniprot id: G2R8Q1
names: Similarity
messages: Belongs to the fructosamine kinase family.

578455:THITE 2109773
gene id: 578455:THITE_2109773
uniprot id: G2QXY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

578455:THITE 2123436
gene id: 578455:THITE_2123436
uniprot id: G2RHD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2118345
gene id: 578455:THITE_2118345
uniprot id: G2R9P9
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

578455:THITE 2124060
gene id: 578455:THITE_2124060
uniprot id: G2RI83
names: Similarity
messages: Belongs to the SELO family.

578455:THITE 2119566
gene id: 578455:THITE_2119566
uniprot id: G2RBY7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

578455:THITE 35412
gene id: 578455:THITE_35412
uniprot id: G2R2U8
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

578455:THITE 2106174
gene id: 578455:THITE_2106174
uniprot id: G2QWL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

578455:THITE 2108759
gene id: 578455:THITE_2108759
uniprot id: G2QSH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2121170
gene id: 578455:THITE_2121170
uniprot id: G2REL8
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

578455:THITE 2109635
gene id: 578455:THITE_2109635
uniprot id: G2QXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

578455:THITE 2113128
gene id: 578455:THITE_2113128
uniprot id: G2R1X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

578455:THITE 2149883
gene id: 578455:THITE_2149883
uniprot id: G2QYN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

578455:THITE 134942
gene id: 578455:THITE_134942
uniprot id: G2RDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

578455:THITE 2120879
gene id: 578455:THITE_2120879
uniprot id: G2RE10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCR10/QCR9 family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 66393
gene id: 578455:THITE_66393
uniprot id: G2R4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

578455:THITE 2109085
gene id: 578455:THITE_2109085
uniprot id: G2QTI3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

578455:THITE 2132082
gene id: 578455:THITE_2132082
uniprot id: G2RCJ2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108800
gene id: 578455:THITE_2108800
uniprot id: G2QSJ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2106560
gene id: 578455:THITE_2106560
uniprot id: G2QQL5
names: Similarity
messages: Belongs to the neutral ceramidase family.

578455:THITE 2074889
gene id: 578455:THITE_2074889
uniprot id: G2QV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2150307
gene id: 578455:THITE_2150307
uniprot id: G2QZ97
names: Similarity
messages: Belongs to the Rho GDI family.

578455:THITE 2106712
gene id: 578455:THITE_2106712
uniprot id: G2QRF0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114792
gene id: 578455:THITE_2114792
uniprot id: G2R1Q8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2120366
gene id: 578455:THITE_2120366
uniprot id: G2RAE2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112774
gene id: 578455:THITE_2112774
uniprot id: G2R0G0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2119240
gene id: 578455:THITE_2119240
uniprot id: G2RBI3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

578455:THITE 2171668
gene id: 578455:THITE_2171668
uniprot id: G2RIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

578455:THITE 2106062
gene id: 578455:THITE_2106062
uniprot id: G2QW12
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121482
gene id: 578455:THITE_2121482
uniprot id: G2REY9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

578455:THITE 120962
gene id: 578455:THITE_120962
uniprot id: G2QXD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

578455:THITE 2110430
gene id: 578455:THITE_2110430
uniprot id: G2QSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Preautophagosomal structure

578455:THITE 134990
gene id: 578455:THITE_134990
uniprot id: G2RCI0
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

578455:THITE 125601
gene id: 578455:THITE_125601
uniprot id: G2R5T7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2145700
gene id: 578455:THITE_2145700
uniprot id: G2R8T0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120553
gene id: 578455:THITE_2120553
uniprot id: G2RCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2039922
gene id: 578455:THITE_2039922
uniprot id: G2QWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

578455:THITE 2124787
gene id: 578455:THITE_2124787
uniprot id: G2RGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 66001
gene id: 578455:THITE_66001
uniprot id: G2R0Q9
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

578455:THITE 2107521
gene id: 578455:THITE_2107521
uniprot id: G2QU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

578455:THITE 2107442
gene id: 578455:THITE_2107442
uniprot id: G2QTV0
names: Similarity
messages: Belongs to the WAPL family.

578455:THITE 2121878
gene id: 578455:THITE_2121878
uniprot id: G2RFF1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

578455:THITE 2107899
gene id: 578455:THITE_2107899
uniprot id: G2QW80
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

578455:THITE 2150941
gene id: 578455:THITE_2150941
uniprot id: G2R815
names: Similarity
messages: Belongs to the SURF6 family.

578455:THITE 2111133
gene id: 578455:THITE_2111133
uniprot id: G2QWL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

578455:THITE 2031888
gene id: 578455:THITE_2031888
uniprot id: G2RAR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2131778
gene id: 578455:THITE_2131778
uniprot id: G2RF13
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 133791
gene id: 578455:THITE_133791
uniprot id: G2QSF5
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

578455:THITE 2116214
gene id: 578455:THITE_2116214
uniprot id: G2R0R6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

578455:THITE 2110971
gene id: 578455:THITE_2110971
uniprot id: G2QVJ2
names: Similarity
messages: Belongs to the peptidase S28 family.

578455:THITE 2118052
gene id: 578455:THITE_2118052
uniprot id: G2R6T7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

578455:THITE 2115984
gene id: 578455:THITE_2115984
uniprot id: G2QZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

578455:THITE 2113840
gene id: 578455:THITE_2113840
uniprot id: G2R4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

578455:THITE 2129363
gene id: 578455:THITE_2129363
uniprot id: G2R5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

578455:THITE 2053914
gene id: 578455:THITE_2053914
uniprot id: G2R8W3
names: Similarity
messages: Belongs to the CoA-transferase III family.

578455:THITE 2120385
gene id: 578455:THITE_2120385
uniprot id: G2RAG4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

578455:THITE 2119436
gene id: 578455:THITE_2119436
uniprot id: G2RBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

578455:THITE 2112061
gene id: 578455:THITE_2112061
uniprot id: G2R4L2
names: Similarity
messages: Belongs to the nuclease type I family.

578455:THITE 2107652
gene id: 578455:THITE_2107652
uniprot id: G2QUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CWC2 family.
messages: Nucleus

578455:THITE 2123218
gene id: 578455:THITE_2123218
uniprot id: G2RH03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

578455:THITE 2106296
gene id: 578455:THITE_2106296
uniprot id: G2QX65
names: Similarity
messages: Belongs to the RRP7 family.

578455:THITE 2107848
gene id: 578455:THITE_2107848
uniprot id: G2QVM2
names: Similarity
messages: Belongs to the IPP transferase family.

578455:THITE 2107851
gene id: 578455:THITE_2107851
uniprot id: G2QVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

578455:THITE 2117327
gene id: 578455:THITE_2117327
uniprot id: G2R7X0
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

578455:THITE 72000
gene id: 578455:THITE_72000
uniprot id: G2R9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

578455:THITE 2116786
gene id: 578455:THITE_2116786
uniprot id: G2R753
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

578455:THITE 2070056
gene id: 578455:THITE_2070056
uniprot id: G2RF62
names: Similarity
messages: Belongs to the 14-3-3 family.

578455:THITE 129437
gene id: 578455:THITE_129437
uniprot id: G2QWQ5
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.

578455:THITE 2117377
gene id: 578455:THITE_2117377
uniprot id: G2R7Z6
names: Similarity
messages: Belongs to the XFP family.

578455:THITE 2113438
gene id: 578455:THITE_2113438
uniprot id: G2R2V8
names: Similarity
messages: Belongs to the RNR ribonuclease family.

578455:THITE 128218
gene id: 578455:THITE_128218
uniprot id: G2R764
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

578455:THITE 2050335
gene id: 578455:THITE_2050335
uniprot id: G2R8N2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118469
gene id: 578455:THITE_2118469
uniprot id: G2RA18
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118572
gene id: 578455:THITE_2118572
uniprot id: G2RAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Nucleus

578455:THITE 2171273
gene id: 578455:THITE_2171273
uniprot id: G2REZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

578455:THITE 69856
gene id: 578455:THITE_69856
uniprot id: G2QUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

578455:THITE 2117232
gene id: 578455:THITE_2117232
uniprot id: G2R7S8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

578455:THITE 2115194
gene id: 578455:THITE_2115194
uniprot id: G2R3H6
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

578455:THITE 2109525
gene id: 578455:THITE_2109525
uniprot id: G2QWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 161557
gene id: 578455:THITE_161557
uniprot id: G2R4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

578455:THITE 2124358
gene id: 578455:THITE_2124358
uniprot id: G2RFR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.
messages: Forms a heterotrimer with H2A.Z-H2B, stabilizing the association of the histone dimer. Also, with a lower affinity, forms a heterotrimer with H2A-H2B.

578455:THITE 2121182
gene id: 578455:THITE_2121182
uniprot id: G2REM4
names: Similarity
messages: Belongs to the synembryn family.

578455:THITE 2109810
gene id: 578455:THITE_2109810
uniprot id: G2QXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

578455:THITE 123928
gene id: 578455:THITE_123928
uniprot id: G2QV13
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

578455:THITE 2116889
gene id: 578455:THITE_2116889
uniprot id: G2R792
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Homododecamer. Adopts a ring-like structure, composed of an arrangement of two hexameric rings stacked on top of one another.
messages: Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.

578455:THITE 2119781
gene id: 578455:THITE_2119781
uniprot id: G2R8V9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

578455:THITE 2115482
gene id: 578455:THITE_2115482
uniprot id: G2R4H8
names: Similarity
messages: Belongs to the synaptobrevin family.

578455:THITE 2112144
gene id: 578455:THITE_2112144
uniprot id: G2R517
names: Similarity
messages: Belongs to the RNase PH family.

578455:THITE 2119393
gene id: 578455:THITE_2119393
uniprot id: G2RBQ9
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2109199
gene id: 578455:THITE_2109199
uniprot id: G2QUB7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2115730
gene id: 578455:THITE_2115730
uniprot id: G2R5E4
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2114852
gene id: 578455:THITE_2114852
uniprot id: G2R250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

578455:THITE 2114015
gene id: 578455:THITE_2114015
uniprot id: G2R557
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

578455:THITE 2119759
gene id: 578455:THITE_2119759
uniprot id: G2RC76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

578455:THITE 2119213
gene id: 578455:THITE_2119213
uniprot id: G2RBH1
names: Similarity
messages: Belongs to the TACO1 family.

578455:THITE 2113187
gene id: 578455:THITE_2113187
uniprot id: G2R1Z6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

578455:THITE 118760
gene id: 578455:THITE_118760
uniprot id: G2R275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

578455:THITE 2058773
gene id: 578455:THITE_2058773
uniprot id: G2RIG7
names: Similarity
messages: Belongs to the TMCO4 family.

578455:THITE 2112405
gene id: 578455:THITE_2112405
uniprot id: G2QYZ9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

578455:THITE 2122929
gene id: 578455:THITE_2122929
uniprot id: G2RGC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

578455:THITE 52603
gene id: 578455:THITE_52603
uniprot id: G2R5Q4
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity.

578455:THITE 2106731
gene id: 578455:THITE_2106731
uniprot id: G2QRG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 35183
gene id: 578455:THITE_35183
uniprot id: G2R0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Secreted

578455:THITE 2117171
gene id: 578455:THITE_2117171
uniprot id: G2R7Q1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

578455:THITE 2053474
gene id: 578455:THITE_2053474
uniprot id: G2R8U2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120470
gene id: 578455:THITE_2120470
uniprot id: G2RAS2
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

578455:THITE 2119199
gene id: 578455:THITE_2119199
uniprot id: G2RBG3
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

578455:THITE 2107614
gene id: 578455:THITE_2107614
uniprot id: G2QUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

578455:THITE 2111173
gene id: 578455:THITE_2111173
uniprot id: G2R0U5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2106707
gene id: 578455:THITE_2106707
uniprot id: G2QR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

578455:THITE 2106135
gene id: 578455:THITE_2106135
uniprot id: G2QW44
names: Similarity
messages: Belongs to the thymidylate kinase family.

578455:THITE 2113133
gene id: 578455:THITE_2113133
uniprot id: G2R1X5
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

578455:THITE 54464
gene id: 578455:THITE_54464
uniprot id: G2R4F1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

578455:THITE 2114762
gene id: 578455:THITE_2114762
uniprot id: G2R1P3
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

578455:THITE 2072867
gene id: 578455:THITE_2072867
uniprot id: G2QU58
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

578455:THITE 2117623
gene id: 578455:THITE_2117623
uniprot id: G2R8D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

578455:THITE 156575
gene id: 578455:THITE_156575
uniprot id: G2RDX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

578455:THITE 2118754
gene id: 578455:THITE_2118754
uniprot id: G2RAV2
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

578455:THITE 2118716
gene id: 578455:THITE_2118716
uniprot id: G2RAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with DNA double-strand breaks.
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.
messages: telomere

578455:THITE 2123969
gene id: 578455:THITE_2123969
uniprot id: G2RI50
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

578455:THITE 2113548
gene id: 578455:THITE_2113548
uniprot id: G2R3B5
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2118509
gene id: 578455:THITE_2118509
uniprot id: G2RA30
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

578455:THITE 118257
gene id: 578455:THITE_118257
uniprot id: G2R0N7
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2112524
gene id: 578455:THITE_2112524
uniprot id: G2QZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

578455:THITE 2110776
gene id: 578455:THITE_2110776
uniprot id: G2QUI0
names: Similarity
messages: Belongs to the cytidylyltransferase family.

578455:THITE 2107318
gene id: 578455:THITE_2107318
uniprot id: G2QTQ3
names: Similarity
messages: Belongs to the DapA family.

578455:THITE 2120107
gene id: 578455:THITE_2120107
uniprot id: G2R9K3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2078396
gene id: 578455:THITE_2078396
uniprot id: G2R6E3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 2110661
gene id: 578455:THITE_2110661
uniprot id: G2QU26
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

578455:THITE 46349
gene id: 578455:THITE_46349
uniprot id: G2RCG7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

578455:THITE 2055279
gene id: 578455:THITE_2055279
uniprot id: G2REJ5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 161092
gene id: 578455:THITE_161092
uniprot id: G2QYH2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 52978
gene id: 578455:THITE_52978
uniprot id: G2R6N2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 134373
gene id: 578455:THITE_134373
uniprot id: G2RA26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

578455:THITE 2107710
gene id: 578455:THITE_2107710
uniprot id: G2QUR2
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

578455:THITE 2110247
gene id: 578455:THITE_2110247
uniprot id: G2QS84
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

578455:THITE 2111882
gene id: 578455:THITE_2111882
uniprot id: G2R419
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117870
gene id: 578455:THITE_2117870
uniprot id: G2R5Y4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

578455:THITE 2114120
gene id: 578455:THITE_2114120
uniprot id: G2QY93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2121512
gene id: 578455:THITE_2121512
uniprot id: G2RF03
names: Similarity
messages: Belongs to the PurH family.

578455:THITE 2107173
gene id: 578455:THITE_2107173
uniprot id: G2QSX9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2130100
gene id: 578455:THITE_2130100
uniprot id: G2R5W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

578455:THITE 2121308
gene id: 578455:THITE_2121308
uniprot id: G2RES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIMR family. LMBRD1 subfamily.
messages: Lysosome membrane
messages: Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors.

578455:THITE 2119283
gene id: 578455:THITE_2119283
uniprot id: G2RBK3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2051797
gene id: 578455:THITE_2051797
uniprot id: G2R8D5
names: Function
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

578455:THITE 2122124
gene id: 578455:THITE_2122124
uniprot id: G2RC96
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2118825
gene id: 578455:THITE_2118825
uniprot id: G2RAX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

578455:THITE 2119848
gene id: 578455:THITE_2119848
uniprot id: G2R8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

578455:THITE 2115535
gene id: 578455:THITE_2115535
uniprot id: G2R4V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2116513
gene id: 578455:THITE_2116513
uniprot id: G2R6F2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

578455:THITE 2121658
gene id: 578455:THITE_2121658
uniprot id: G2RF64
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

578455:THITE 2171338
gene id: 578455:THITE_2171338
uniprot id: G2RFH1
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117168
gene id: 578455:THITE_2117168
uniprot id: G2R7Q0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 164085
gene id: 578455:THITE_164085
uniprot id: G2RE13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
messages: Binds to histones H3 and H4.
messages: PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. Proline isomerization influences H3 methylation thereby regulating gene expression.

578455:THITE 2107474
gene id: 578455:THITE_2107474
uniprot id: G2QU67
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

578455:THITE 2119013
gene id: 578455:THITE_2119013
uniprot id: G2RB57
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2114840
gene id: 578455:THITE_2114840
uniprot id: G2R245
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

578455:THITE 2121368
gene id: 578455:THITE_2121368
uniprot id: G2REU9
names: Similarity
messages: Belongs to the cyclin family.

578455:THITE 2119293
gene id: 578455:THITE_2119293
uniprot id: G2RBK7
names: Similarity
messages: Belongs to the yippee family.

578455:THITE 134020
gene id: 578455:THITE_134020
uniprot id: G2QXC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.

578455:THITE 2108652
gene id: 578455:THITE_2108652
uniprot id: G2QS29
names: Function
names: Similarity
messages: Belongs to the FES1 family.
messages: Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins.

578455:THITE 2122998
gene id: 578455:THITE_2122998
uniprot id: G2RGF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

578455:THITE 2117340
gene id: 578455:THITE_2117340
uniprot id: G2R7Y0
names: Function
names: Subcellular Location Annotation
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

578455:THITE 2025173
gene id: 578455:THITE_2025173
uniprot id: G2R0Q0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

578455:THITE 2111645
gene id: 578455:THITE_2111645
uniprot id: G2R357
names: Similarity
messages: Belongs to the complex I LYR family.

578455:THITE 2114060
gene id: 578455:THITE_2114060
uniprot id: G2R579
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space
messages: Required for the assembly of cytochrome c oxidase.

578455:THITE 2108794
gene id: 578455:THITE_2108794
uniprot id: G2QSJ1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

578455:THITE 153800
gene id: 578455:THITE_153800
uniprot id: G2QX74
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

578455:THITE 2109233
gene id: 578455:THITE_2109233
uniprot id: G2QUE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

578455:THITE 2120233
gene id: 578455:THITE_2120233
uniprot id: G2R9V2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2121387
gene id: 578455:THITE_2121387
uniprot id: G2REV5
names: Similarity
messages: Belongs to the NAPRTase family.

578455:THITE 2119656
gene id: 578455:THITE_2119656
uniprot id: G2RC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2112562
gene id: 578455:THITE_2112562
uniprot id: G2QZH3
names: Similarity
messages: Belongs to the cytochrome b5 family.

578455:THITE 2121621
gene id: 578455:THITE_2121621
uniprot id: G2RF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 40124
gene id: 578455:THITE_40124
uniprot id: G2QV86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

578455:THITE 2171300
gene id: 578455:THITE_2171300
uniprot id: G2RF66
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

578455:THITE 2122285
gene id: 578455:THITE_2122285
uniprot id: G2RCP9
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

578455:THITE 2090861
gene id: 578455:THITE_2090861
uniprot id: G2RC48
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

578455:THITE 2119856
gene id: 578455:THITE_2119856
uniprot id: G2R8Z3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

578455:THITE 2117456
gene id: 578455:THITE_2117456
uniprot id: G2R832
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

578455:THITE 75273
gene id: 578455:THITE_75273
uniprot id: G2RHM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

578455:THITE 2114134
gene id: 578455:THITE_2114134
uniprot id: G2QY97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

578455:THITE 2115327
gene id: 578455:THITE_2115327
uniprot id: G2R401
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2109347
gene id: 578455:THITE_2109347
uniprot id: G2QUV9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

578455:THITE 2116855
gene id: 578455:THITE_2116855
uniprot id: G2R779
names: Function
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 2049821
gene id: 578455:THITE_2049821
uniprot id: G2R717
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

578455:THITE 2109103
gene id: 578455:THITE_2109103
uniprot id: G2QTI9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.

578455:THITE 2123954
gene id: 578455:THITE_2123954
uniprot id: G2RI45
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

578455:THITE 2108544
gene id: 578455:THITE_2108544
uniprot id: G2QRN6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

578455:THITE 2115076
gene id: 578455:THITE_2115076
uniprot id: G2R313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.

578455:THITE 2116140
gene id: 578455:THITE_2116140
uniprot id: G2R077
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116099
gene id: 578455:THITE_2116099
uniprot id: G2QZV7
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

578455:THITE 2123364
gene id: 578455:THITE_2123364
uniprot id: G2RH90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

578455:THITE 2111563
gene id: 578455:THITE_2111563
uniprot id: G2R2S6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2045627
gene id: 578455:THITE_2045627
uniprot id: G2R533
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

578455:THITE 2170008
gene id: 578455:THITE_2170008
uniprot id: G2QZI3
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

578455:THITE 2111999
gene id: 578455:THITE_2111999
uniprot id: G2R4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

578455:THITE 2150534
gene id: 578455:THITE_2150534
uniprot id: G2R4U0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 118371
gene id: 578455:THITE_118371
uniprot id: G2QZC2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2048302
gene id: 578455:THITE_2048302
uniprot id: G2QY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

578455:THITE 47305
gene id: 578455:THITE_47305
uniprot id: G2QVI9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2040127
gene id: 578455:THITE_2040127
uniprot id: G2QV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2110188
gene id: 578455:THITE_2110188
uniprot id: G2QRV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

578455:THITE 2120324
gene id: 578455:THITE_2120324
uniprot id: G2RA62
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

578455:THITE 2106709
gene id: 578455:THITE_2106709
uniprot id: G2QR40
names: Similarity
messages: Belongs to the UreD family.

578455:THITE 2114944
gene id: 578455:THITE_2114944
uniprot id: G2R2J7
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

578455:THITE 2123415
gene id: 578455:THITE_2123415
uniprot id: G2RHC4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2141870
gene id: 578455:THITE_2141870
uniprot id: G2QVS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.
messages: Mitochondrion matrix

578455:THITE 2038228
gene id: 578455:THITE_2038228
uniprot id: G2QSH2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

578455:THITE 2150620
gene id: 578455:THITE_2150620
uniprot id: G2QYW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.

578455:THITE 2115741
gene id: 578455:THITE_2115741
uniprot id: G2R5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2120011
gene id: 578455:THITE_2120011
uniprot id: G2R9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.

578455:THITE 2108552
gene id: 578455:THITE_2108552
uniprot id: G2QRN7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 2037188
gene id: 578455:THITE_2037188
uniprot id: G2QVH1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 37279
gene id: 578455:THITE_37279
uniprot id: G2R3L9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2130161
gene id: 578455:THITE_2130161
uniprot id: G2R681
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 134656
gene id: 578455:THITE_134656
uniprot id: G2RC77
names: Similarity
messages: Belongs to the CWC22 family.

578455:THITE 2111560
gene id: 578455:THITE_2111560
uniprot id: G2R2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

578455:THITE 2123514
gene id: 578455:THITE_2123514
uniprot id: G2RHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

578455:THITE 2120484
gene id: 578455:THITE_2120484
uniprot id: G2RAS9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2123225
gene id: 578455:THITE_2123225
uniprot id: G2RH06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

578455:THITE 2046339
gene id: 578455:THITE_2046339
uniprot id: G2QYR9
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

578455:THITE 2125708
gene id: 578455:THITE_2125708
uniprot id: G2QXD1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2144774
gene id: 578455:THITE_2144774
uniprot id: G2R1A4
names: Similarity
messages: Belongs to the peptidase S10 family.

578455:THITE 2121054
gene id: 578455:THITE_2121054
uniprot id: G2REC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

578455:THITE 2106470
gene id: 578455:THITE_2106470
uniprot id: G2QXQ2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2123361
gene id: 578455:THITE_2123361
uniprot id: G2RH88
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

578455:THITE 2108194
gene id: 578455:THITE_2108194
uniprot id: G2QXW9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

578455:THITE 75670
gene id: 578455:THITE_75670
uniprot id: G2RIG4
names: Similarity
messages: Belongs to the TRAPPC13 family.

578455:THITE 2044835
gene id: 578455:THITE_2044835
uniprot id: G2R569
names: Similarity
messages: Belongs to the SUA5 family.

578455:THITE 115927
gene id: 578455:THITE_115927
uniprot id: G2QSP5
names: Similarity
messages: Belongs to the XPC family.

578455:THITE 2132357
gene id: 578455:THITE_2132357
uniprot id: G2REH6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2047808
gene id: 578455:THITE_2047808
uniprot id: G2R4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

578455:THITE 2110748
gene id: 578455:THITE_2110748
uniprot id: G2QU60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

578455:THITE 34254
gene id: 578455:THITE_34254
uniprot id: G2QYJ3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117999
gene id: 578455:THITE_2117999
uniprot id: G2R6H7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

578455:THITE 2117724
gene id: 578455:THITE_2117724
uniprot id: G2R8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Secreted

578455:THITE 2112966
gene id: 578455:THITE_2112966
uniprot id: G2R1G5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

578455:THITE 2118331
gene id: 578455:THITE_2118331
uniprot id: G2R9P1
names: Similarity
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.

578455:THITE 2119562
gene id: 578455:THITE_2119562
uniprot id: G2RBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 2122804
gene id: 578455:THITE_2122804
uniprot id: G2RE89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

578455:THITE 57625
gene id: 578455:THITE_57625
uniprot id: G2QRH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

578455:THITE 2108406
gene id: 578455:THITE_2108406
uniprot id: G2QR66
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 68068
gene id: 578455:THITE_68068
uniprot id: G2R0D0
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

578455:THITE 2169734
gene id: 578455:THITE_2169734
uniprot id: G2QUM1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

578455:THITE 160710
gene id: 578455:THITE_160710
uniprot id: G2R6G6
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2116289
gene id: 578455:THITE_2116289
uniprot id: G2R196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

578455:THITE 2131460
gene id: 578455:THITE_2131460
uniprot id: G2RD72
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2118216
gene id: 578455:THITE_2118216
uniprot id: G2R937
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 2114384
gene id: 578455:THITE_2114384
uniprot id: G2QZL8
names: Similarity
messages: Belongs to the MTFP1 family.

578455:THITE 2116431
gene id: 578455:THITE_2116431
uniprot id: G2R5V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.
messages: Belongs to the pectinesterase family.

578455:THITE 2122013
gene id: 578455:THITE_2122013
uniprot id: G2RFL1
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

578455:THITE 2121748
gene id: 578455:THITE_2121748
uniprot id: G2RF91
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

578455:THITE 2169422
gene id: 578455:THITE_2169422
uniprot id: G2QR49
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

578455:THITE 2108627
gene id: 578455:THITE_2108627
uniprot id: G2QS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

578455:THITE 2042114
gene id: 578455:THITE_2042114
uniprot id: G2QTP0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2119890
gene id: 578455:THITE_2119890
uniprot id: G2R907
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

578455:THITE 2111674
gene id: 578455:THITE_2111674
uniprot id: G2R370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane

578455:THITE 2113692
gene id: 578455:THITE_2113692
uniprot id: G2R3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

578455:THITE 118678
gene id: 578455:THITE_118678
uniprot id: G2R336
names: Similarity
messages: Belongs to the CoA-transferase III family.

578455:THITE 2112932
gene id: 578455:THITE_2112932
uniprot id: G2R0Z8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2117619
gene id: 578455:THITE_2117619
uniprot id: G2R8D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2112467
gene id: 578455:THITE_2112467
uniprot id: G2QZ24
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2088224
gene id: 578455:THITE_2088224
uniprot id: G2R329
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122161
gene id: 578455:THITE_2122161
uniprot id: G2RCB5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113646
gene id: 578455:THITE_2113646
uniprot id: G2R3R8
names: Similarity
messages: Belongs to the PP2C family.

578455:THITE 2111296
gene id: 578455:THITE_2111296
uniprot id: G2R1T2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2118769
gene id: 578455:THITE_2118769
uniprot id: G2RAV7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: Membrane
messages: actin patch

578455:THITE 2122146
gene id: 578455:THITE_2122146
uniprot id: G2RCA4
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

578455:THITE 2059487
gene id: 578455:THITE_2059487
uniprot id: G2RGE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2126993
gene id: 578455:THITE_2126993
uniprot id: G2QVV5
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

578455:THITE 2116246
gene id: 578455:THITE_2116246
uniprot id: G2R163
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118808
gene id: 578455:THITE_2118808
uniprot id: G2RAW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

578455:THITE 2117803
gene id: 578455:THITE_2117803
uniprot id: G2R5N8
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

578455:THITE 74295
gene id: 578455:THITE_74295
uniprot id: G2QRV6
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

578455:THITE 2115374
gene id: 578455:THITE_2115374
uniprot id: G2R4C8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

578455:THITE 2119694
gene id: 578455:THITE_2119694
uniprot id: G2RC50
names: Function
names: Similarity
messages: Belongs to the EFG1 family.
messages: Involved in rRNA processing.

578455:THITE 2110846
gene id: 578455:THITE_2110846
uniprot id: G2QUL3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

578455:THITE 2115037
gene id: 578455:THITE_2115037
uniprot id: G2R2Z5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122369
gene id: 578455:THITE_2122369
uniprot id: G2RCZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions.

578455:THITE 2170952
gene id: 578455:THITE_2170952
uniprot id: G2RBN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

578455:THITE 2109747
gene id: 578455:THITE_2109747
uniprot id: G2QXL4
names: Similarity
messages: Belongs to the SH3YL1 family.

578455:THITE 2111697
gene id: 578455:THITE_2111697
uniprot id: G2R378
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

578455:THITE 2111949
gene id: 578455:THITE_2111949
uniprot id: G2R447
names: Similarity
messages: Belongs to the PET191 family.

578455:THITE 2070023
gene id: 578455:THITE_2070023
uniprot id: G2RF41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

578455:THITE 53797
gene id: 578455:THITE_53797
uniprot id: G2R8I5
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2123901
gene id: 578455:THITE_2123901
uniprot id: G2RI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

578455:THITE 2120877
gene id: 578455:THITE_2120877
uniprot id: G2RDV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2117366
gene id: 578455:THITE_2117366
uniprot id: G2R7Y9
names: Similarity
messages: Belongs to the RPAP1 family.

578455:THITE 2110886
gene id: 578455:THITE_2110886
uniprot id: G2QUZ2
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2112026
gene id: 578455:THITE_2112026
uniprot id: G2R4J5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

578455:THITE 2143998
gene id: 578455:THITE_2143998
uniprot id: G2R065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2111253
gene id: 578455:THITE_2111253
uniprot id: G2R1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

578455:THITE 2146658
gene id: 578455:THITE_2146658
uniprot id: G2RAH3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2051078
gene id: 578455:THITE_2051078
uniprot id: G2R876
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2097288
gene id: 578455:THITE_2097288
uniprot id: G2RFL9
names: Similarity
messages: Belongs to the MIP18 family.

578455:THITE 2119663
gene id: 578455:THITE_2119663
uniprot id: G2RC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

578455:THITE 61645
gene id: 578455:THITE_61645
uniprot id: G2REZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

578455:THITE 2118559
gene id: 578455:THITE_2118559
uniprot id: G2RAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

578455:THITE 2116403
gene id: 578455:THITE_2116403
uniprot id: G2R5S8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118105
gene id: 578455:THITE_2118105
uniprot id: G2R6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

578455:THITE 2115106
gene id: 578455:THITE_2115106
uniprot id: G2R330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

578455:THITE 2118432
gene id: 578455:THITE_2118432
uniprot id: G2RA04
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

578455:THITE 2112176
gene id: 578455:THITE_2112176
uniprot id: G2R534
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2109021
gene id: 578455:THITE_2109021
uniprot id: G2QTF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Preautophagosomal structure membrane

578455:THITE 2111977
gene id: 578455:THITE_2111977
uniprot id: G2R463
names: Similarity
messages: Belongs to the pirin family.

578455:THITE 114886
gene id: 578455:THITE_114886
uniprot id: G2RFD3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124446
gene id: 578455:THITE_2124446
uniprot id: G2RFU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

578455:THITE 2089488
gene id: 578455:THITE_2089488
uniprot id: G2R7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2089378
gene id: 578455:THITE_2089378
uniprot id: G2R7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

578455:THITE 2122835
gene id: 578455:THITE_2122835
uniprot id: G2REA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

578455:THITE 2097947
gene id: 578455:THITE_2097947
uniprot id: G2RGL8
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

578455:THITE 2112746
gene id: 578455:THITE_2112746
uniprot id: G2R0D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2113558
gene id: 578455:THITE_2113558
uniprot id: G2R3B8
names: Similarity
messages: Belongs to the beclin family.

578455:THITE 2108277
gene id: 578455:THITE_2108277
uniprot id: G2QQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

578455:THITE 2120545
gene id: 578455:THITE_2120545
uniprot id: G2RCL3
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2047968
gene id: 578455:THITE_2047968
uniprot id: G2R4C5
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

578455:THITE 164977
gene id: 578455:THITE_164977
uniprot id: G2RFP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2116296
gene id: 578455:THITE_2116296
uniprot id: G2R1A0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2115138
gene id: 578455:THITE_2115138
uniprot id: G2R345
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

578455:THITE 2111616
gene id: 578455:THITE_2111616
uniprot id: G2R348
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

578455:THITE 2108605
gene id: 578455:THITE_2108605
uniprot id: G2QRQ5
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

578455:THITE 64761
gene id: 578455:THITE_64761
uniprot id: G2R738
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

578455:THITE 2119979
gene id: 578455:THITE_2119979
uniprot id: G2R9A3
names: Similarity
messages: Belongs to the KRI1 family.

578455:THITE 43414
gene id: 578455:THITE_43414
uniprot id: G2RA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2115090
gene id: 578455:THITE_2115090
uniprot id: G2R318
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 44575
gene id: 578455:THITE_44575
uniprot id: G2RCY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2115883
gene id: 578455:THITE_2115883
uniprot id: G2QYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

578455:THITE 2113208
gene id: 578455:THITE_2113208
uniprot id: G2R206
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

578455:THITE 2117649
gene id: 578455:THITE_2117649
uniprot id: G2R8G4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

578455:THITE 2117664
gene id: 578455:THITE_2117664
uniprot id: G2R8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: Required for pre-18S rRNA processing. May bind microtubules.
messages: nucleolus

578455:THITE 2108995
gene id: 578455:THITE_2108995
uniprot id: G2QT32
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

578455:THITE 158792
gene id: 578455:THITE_158792
uniprot id: G2RGE4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2123166
gene id: 578455:THITE_2123166
uniprot id: G2RGY0
names: Similarity
messages: Belongs to the OMP decarboxylase family.

578455:THITE 2116945
gene id: 578455:THITE_2116945
uniprot id: G2R7C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

578455:THITE 46100
gene id: 578455:THITE_46100
uniprot id: G2RCD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

578455:THITE 2106524
gene id: 578455:THITE_2106524
uniprot id: G2QQJ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2110149
gene id: 578455:THITE_2110149
uniprot id: G2QRT2
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

578455:THITE 2112315
gene id: 578455:THITE_2112315
uniprot id: G2QYJ9
names: Similarity
messages: Belongs to the SPT2 family.

578455:THITE 2120798
gene id: 578455:THITE_2120798
uniprot id: G2RDR8
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

578455:THITE 2109645
gene id: 578455:THITE_2109645
uniprot id: G2QXH1
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

578455:THITE 2111513
gene id: 578455:THITE_2111513
uniprot id: G2R2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

578455:THITE 2110161
gene id: 578455:THITE_2110161
uniprot id: G2QRT6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

578455:THITE 2044372
gene id: 578455:THITE_2044372
uniprot id: G2QZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2109062
gene id: 578455:THITE_2109062
uniprot id: G2QTH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2119963
gene id: 578455:THITE_2119963
uniprot id: G2R991
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2122612
gene id: 578455:THITE_2122612
uniprot id: G2RDN0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

578455:THITE 2110372
gene id: 578455:THITE_2110372
uniprot id: G2QSP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.

578455:THITE 2115394
gene id: 578455:THITE_2115394
uniprot id: G2R4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

578455:THITE 2169677
gene id: 578455:THITE_2169677
uniprot id: G2QT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Mitochondrion inner membrane

578455:THITE 2146636
gene id: 578455:THITE_2146636
uniprot id: G2RAE1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2047449
gene id: 578455:THITE_2047449
uniprot id: G2R4X7
names: Similarity
messages: Belongs to the CWC26 family.

578455:THITE 2118079
gene id: 578455:THITE_2118079
uniprot id: G2R6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

578455:THITE 52692
gene id: 578455:THITE_52692
uniprot id: G2R5W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nitrate reductase family.
messages: Homodimer.
messages: Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.

578455:THITE 76823
gene id: 578455:THITE_76823
uniprot id: G2R7A9
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

578455:THITE 2108806
gene id: 578455:THITE_2108806
uniprot id: G2QSJ6
names: Similarity
messages: Belongs to the PhyH family.

578455:THITE 47560
gene id: 578455:THITE_47560
uniprot id: G2QVI4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123903
gene id: 578455:THITE_2123903
uniprot id: G2RI25
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 2106553
gene id: 578455:THITE_2106553
uniprot id: G2QQL0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

578455:THITE 2124219
gene id: 578455:THITE_2124219
uniprot id: G2RIE9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2074474
gene id: 578455:THITE_2074474
uniprot id: G2QS55
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2116929
gene id: 578455:THITE_2116929
uniprot id: G2R7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

578455:THITE 2050968
gene id: 578455:THITE_2050968
uniprot id: G2R6U7
names: Similarity
messages: Belongs to the OSBP family.

578455:THITE 2124570
gene id: 578455:THITE_2124570
uniprot id: G2RG00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

578455:THITE 2148801
gene id: 578455:THITE_2148801
uniprot id: G2QTD6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.

578455:THITE 2131921
gene id: 578455:THITE_2131921
uniprot id: G2RFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

578455:THITE 2060065
gene id: 578455:THITE_2060065
uniprot id: G2RHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

578455:THITE 2109493
gene id: 578455:THITE_2109493
uniprot id: G2QWB5
names: Similarity
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.

578455:THITE 2115983
gene id: 578455:THITE_2115983
uniprot id: G2QZC4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122802
gene id: 578455:THITE_2122802
uniprot id: G2RE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

578455:THITE 2124480
gene id: 578455:THITE_2124480
uniprot id: G2RFV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

578455:THITE 2067339
gene id: 578455:THITE_2067339
uniprot id: G2R838
names: Similarity
messages: Belongs to the MOG1 family.

578455:THITE 2116926
gene id: 578455:THITE_2116926
uniprot id: G2R7B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

578455:THITE 2082751
gene id: 578455:THITE_2082751
uniprot id: G2RH96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

578455:THITE 2124217
gene id: 578455:THITE_2124217
uniprot id: G2RIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2108516
gene id: 578455:THITE_2108516
uniprot id: G2QRM5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

578455:THITE 2046476
gene id: 578455:THITE_2046476
uniprot id: G2R4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

578455:THITE 2110260
gene id: 578455:THITE_2110260
uniprot id: G2QS91
names: Similarity
messages: Belongs to the MSOX/MTOX family.

578455:THITE 157774
gene id: 578455:THITE_157774
uniprot id: G2QVS4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113984
gene id: 578455:THITE_2113984
uniprot id: G2R545
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2113495
gene id: 578455:THITE_2113495
uniprot id: G2R2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

578455:THITE 2169643
gene id: 578455:THITE_2169643
uniprot id: G2QS74
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

578455:THITE 2123092
gene id: 578455:THITE_2123092
uniprot id: G2RGP9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

578455:THITE 2112705
gene id: 578455:THITE_2112705
uniprot id: G2R011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

578455:THITE 2113234
gene id: 578455:THITE_2113234
uniprot id: G2R213
names: Similarity
messages: Belongs to the OSBP family.

578455:THITE 136564
gene id: 578455:THITE_136564
uniprot id: G2R763
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

578455:THITE 2090091
gene id: 578455:THITE_2090091
uniprot id: G2R8T2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2153075
gene id: 578455:THITE_2153075
uniprot id: G2QXU1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

578455:THITE 2110221
gene id: 578455:THITE_2110221
uniprot id: G2QS73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

578455:THITE 2078040
gene id: 578455:THITE_2078040
uniprot id: G2R103
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

578455:THITE 43019
gene id: 578455:THITE_43019
uniprot id: G2R921
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

578455:THITE 2108755
gene id: 578455:THITE_2108755
uniprot id: G2QSH5
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family. G(q) subfamily.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

578455:THITE 2113496
gene id: 578455:THITE_2113496
uniprot id: G2R2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

578455:THITE 2111327
gene id: 578455:THITE_2111327
uniprot id: G2R1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

578455:THITE 2170062
gene id: 578455:THITE_2170062
uniprot id: G2R1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.

578455:THITE 2121818
gene id: 578455:THITE_2121818
uniprot id: G2RFC4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

578455:THITE 2092533
gene id: 578455:THITE_2092533
uniprot id: G2RGE0
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2124456
gene id: 578455:THITE_2124456
uniprot id: G2RFV1
names: Similarity
messages: Belongs to the citrate synthase family.

578455:THITE 2120772
gene id: 578455:THITE_2120772
uniprot id: G2RDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

578455:THITE 2114098
gene id: 578455:THITE_2114098
uniprot id: G2QY84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S9B family.
messages: Membrane
messages: Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
messages: Vacuole membrane

578455:THITE 36409
gene id: 578455:THITE_36409
uniprot id: G2R069
names: Similarity
messages: Belongs to the cytochrome b5 family.

578455:THITE 2093517
gene id: 578455:THITE_2093517
uniprot id: G2QWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
messages: Membrane
messages: Preautophagosomal structure membrane

578455:THITE 127365
gene id: 578455:THITE_127365
uniprot id: G2RF57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2150040
gene id: 578455:THITE_2150040
uniprot id: G2R1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

578455:THITE 2109723
gene id: 578455:THITE_2109723
uniprot id: G2QXK4
names: Subunit
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.

578455:THITE 2115568
gene id: 578455:THITE_2115568
uniprot id: G2R4X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2123022
gene id: 578455:THITE_2123022
uniprot id: G2RGM1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

578455:THITE 2081050
gene id: 578455:THITE_2081050
uniprot id: G2RD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

578455:THITE 2115877
gene id: 578455:THITE_2115877
uniprot id: G2QYU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

578455:THITE 2118618
gene id: 578455:THITE_2118618
uniprot id: G2RAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

578455:THITE 2146723
gene id: 578455:THITE_2146723
uniprot id: G2RCJ9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2143774
gene id: 578455:THITE_2143774
uniprot id: G2R563
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

578455:THITE 2155922
gene id: 578455:THITE_2155922
uniprot id: G2RAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

578455:THITE 2037431
gene id: 578455:THITE_2037431
uniprot id: G2QWJ7
names: Similarity
messages: Belongs to the peptidase S33 family.

578455:THITE 2114055
gene id: 578455:THITE_2114055
uniprot id: G2R574
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

578455:THITE 68287
gene id: 578455:THITE_68287
uniprot id: G2QYL4
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 72705
gene id: 578455:THITE_72705
uniprot id: G2RCG3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2123430
gene id: 578455:THITE_2123430
uniprot id: G2RHD3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109881
gene id: 578455:THITE_2109881
uniprot id: G2QQU2
names: Similarity
messages: Belongs to the TSR2 family.

578455:THITE 2108029
gene id: 578455:THITE_2108029
uniprot id: G2QWW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

578455:THITE 127477
gene id: 578455:THITE_127477
uniprot id: G2RDT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

578455:THITE 2115508
gene id: 578455:THITE_2115508
uniprot id: G2R4U6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117750
gene id: 578455:THITE_2117750
uniprot id: G2R8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

578455:THITE 2077439
gene id: 578455:THITE_2077439
uniprot id: G2R3E3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107582
gene id: 578455:THITE_2107582
uniprot id: G2QUA4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

578455:THITE 2091753
gene id: 578455:THITE_2091753
uniprot id: G2REX3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 128077
gene id: 578455:THITE_128077
uniprot id: G2R5X9
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2119224
gene id: 578455:THITE_2119224
uniprot id: G2RBH6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

578455:THITE 2124524
gene id: 578455:THITE_2124524
uniprot id: G2RFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

578455:THITE 2111309
gene id: 578455:THITE_2111309
uniprot id: G2R1U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

578455:THITE 2106718
gene id: 578455:THITE_2106718
uniprot id: G2QRF3
names: Similarity
messages: Belongs to the cyclin family.

578455:THITE 2124844
gene id: 578455:THITE_2124844
uniprot id: G2RGW4
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

578455:THITE 2121173
gene id: 578455:THITE_2121173
uniprot id: G2REL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

578455:THITE 2109761
gene id: 578455:THITE_2109761
uniprot id: G2QXX8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2110877
gene id: 578455:THITE_2110877
uniprot id: G2QUY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

578455:THITE 2107389
gene id: 578455:THITE_2107389
uniprot id: G2QTT0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2074814
gene id: 578455:THITE_2074814
uniprot id: G2QUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2107881
gene id: 578455:THITE_2107881
uniprot id: G2QW62
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2122258
gene id: 578455:THITE_2122258
uniprot id: G2RCI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

578455:THITE 2114056
gene id: 578455:THITE_2114056
uniprot id: G2R575
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

578455:THITE 2114013
gene id: 578455:THITE_2114013
uniprot id: G2R555
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

578455:THITE 2120869
gene id: 578455:THITE_2120869
uniprot id: G2RDV0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2075346
gene id: 578455:THITE_2075346
uniprot id: G2R2P4
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

578455:THITE 2117338
gene id: 578455:THITE_2117338
uniprot id: G2R7X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

578455:THITE 113168
gene id: 578455:THITE_113168
uniprot id: G2QSY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2118746
gene id: 578455:THITE_2118746
uniprot id: G2RAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

578455:THITE 2156567
gene id: 578455:THITE_2156567
uniprot id: G2RH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

578455:THITE 42108
gene id: 578455:THITE_42108
uniprot id: G2RB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

578455:THITE 2113698
gene id: 578455:THITE_2113698
uniprot id: G2R3T8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

578455:THITE 2170947
gene id: 578455:THITE_2170947
uniprot id: G2RBL7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

578455:THITE 2118774
gene id: 578455:THITE_2118774
uniprot id: G2RAV8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2124349
gene id: 578455:THITE_2124349
uniprot id: G2RFR2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

578455:THITE 2106073
gene id: 578455:THITE_2106073
uniprot id: G2QW17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

578455:THITE 2086774
gene id: 578455:THITE_2086774
uniprot id: G2R516
names: Similarity
messages: Belongs to the Rab GDI family.

578455:THITE 2119446
gene id: 578455:THITE_2119446
uniprot id: G2RBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

578455:THITE 2111128
gene id: 578455:THITE_2111128
uniprot id: G2QWK7
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

578455:THITE 2169343
gene id: 578455:THITE_2169343
uniprot id: G2QV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

578455:THITE 2119481
gene id: 578455:THITE_2119481
uniprot id: G2RBV1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 53349
gene id: 578455:THITE_53349
uniprot id: G2R5R3
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2118386
gene id: 578455:THITE_2118386
uniprot id: G2R9Y4
names: Similarity
messages: Belongs to the PP2C family.

578455:THITE 2090100
gene id: 578455:THITE_2090100
uniprot id: G2R8U1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 43808
gene id: 578455:THITE_43808
uniprot id: G2R8Y3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2122943
gene id: 578455:THITE_2122943
uniprot id: G2RGD4
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

578455:THITE 2124052
gene id: 578455:THITE_2124052
uniprot id: G2RI78
names: Subunit
messages: Homodimer.

578455:THITE 54120
gene id: 578455:THITE_54120
uniprot id: G2QZD0
names: Function
names: Similarity
messages: Belongs to the POA1 family.
messages: Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.

578455:THITE 2106126
gene id: 578455:THITE_2106126
uniprot id: G2QW40
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2116470
gene id: 578455:THITE_2116470
uniprot id: G2R647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2115270
gene id: 578455:THITE_2115270
uniprot id: G2R3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

578455:THITE 2116536
gene id: 578455:THITE_2116536
uniprot id: G2R6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2154163
gene id: 578455:THITE_2154163
uniprot id: G2R1H9
names: Similarity
messages: Belongs to the VPS26 family.

578455:THITE 2110289
gene id: 578455:THITE_2110289
uniprot id: G2QSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2122701
gene id: 578455:THITE_2122701
uniprot id: G2RDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2113930
gene id: 578455:THITE_2113930
uniprot id: G2R4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

578455:THITE 2115125
gene id: 578455:THITE_2115125
uniprot id: G2R337
names: Similarity
messages: Belongs to the RNase PH family.

578455:THITE 120212
gene id: 578455:THITE_120212
uniprot id: G2QW16
names: Cofactor
messages: Binds 2 manganese ions per subunit.

578455:THITE 2122249
gene id: 578455:THITE_2122249
uniprot id: G2RCI1
names: Similarity
messages: Belongs to the peptidase M67A family.

578455:THITE 59363
gene id: 578455:THITE_59363
uniprot id: G2R9Y2
names: Similarity
messages: Belongs to the Tom22 family.

578455:THITE 2117337
gene id: 578455:THITE_2117337
uniprot id: G2R7X7
names: Similarity
messages: Belongs to the BolA/IbaG family.

578455:THITE 2115364
gene id: 578455:THITE_2115364
uniprot id: G2R4C7
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

578455:THITE 119631
gene id: 578455:THITE_119631
uniprot id: G2QZJ1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2093483
gene id: 578455:THITE_2093483
uniprot id: G2QW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2113911
gene id: 578455:THITE_2113911
uniprot id: G2R4P7
names: Similarity
messages: Belongs to the DeSI family.

578455:THITE 110127
gene id: 578455:THITE_110127
uniprot id: G2QYF2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

578455:THITE 122455
gene id: 578455:THITE_122455
uniprot id: G2RDW2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2082945
gene id: 578455:THITE_2082945
uniprot id: G2RHS3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

578455:THITE 2083552
gene id: 578455:THITE_2083552
uniprot id: G2RG82
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108142
gene id: 578455:THITE_2108142
uniprot id: G2QXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2114954
gene id: 578455:THITE_2114954
uniprot id: G2R2K4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109048
gene id: 578455:THITE_2109048
uniprot id: G2QTG6
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

578455:THITE 2123725
gene id: 578455:THITE_2123725
uniprot id: G2RHU4
names: Similarity
messages: Belongs to the allantoicase family.

578455:THITE 2113172
gene id: 578455:THITE_2113172
uniprot id: G2R1Y8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

578455:THITE 2115692
gene id: 578455:THITE_2115692
uniprot id: G2R5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

578455:THITE 162966
gene id: 578455:THITE_162966
uniprot id: G2QTW1
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

578455:THITE 68454
gene id: 578455:THITE_68454
uniprot id: G2R4M1
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

578455:THITE 2113169
gene id: 578455:THITE_2113169
uniprot id: G2R1Y6
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

578455:THITE 2116212
gene id: 578455:THITE_2116212
uniprot id: G2R0R4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118397
gene id: 578455:THITE_2118397
uniprot id: G2R9Y8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

578455:THITE 2107066
gene id: 578455:THITE_2107066
uniprot id: G2QSG4
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

578455:THITE 2114167
gene id: 578455:THITE_2114167
uniprot id: G2QYA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

578455:THITE 2115499
gene id: 578455:THITE_2115499
uniprot id: G2R4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

578455:THITE 2110893
gene id: 578455:THITE_2110893
uniprot id: G2QUZ9
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

578455:THITE 2037550
gene id: 578455:THITE_2037550
uniprot id: G2QRY3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

578455:THITE 2110849
gene id: 578455:THITE_2110849
uniprot id: G2QUL5
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

578455:THITE 2110565
gene id: 578455:THITE_2110565
uniprot id: G2QTK8
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

578455:THITE 2092830
gene id: 578455:THITE_2092830
uniprot id: G2RHL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

578455:THITE 126920
gene id: 578455:THITE_126920
uniprot id: G2RA99
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

578455:THITE 56072
gene id: 578455:THITE_56072
uniprot id: G2R0Y8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

578455:THITE 55782
gene id: 578455:THITE_55782
uniprot id: G2R2G6
names: Similarity
messages: Belongs to the NXF family.

578455:THITE 2169729
gene id: 578455:THITE_2169729
uniprot id: G2QUK7
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2015092
gene id: 578455:THITE_2015092
uniprot id: G2RAL3
names: Similarity
messages: Belongs to the COG1 family.

578455:THITE 2068463
gene id: 578455:THITE_2068463
uniprot id: G2RBH7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

578455:THITE 2073214
gene id: 578455:THITE_2073214
uniprot id: G2QQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

578455:THITE 2111897
gene id: 578455:THITE_2111897
uniprot id: G2R426
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.

578455:THITE 2121023
gene id: 578455:THITE_2121023
uniprot id: G2RE62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

578455:THITE 2123245
gene id: 578455:THITE_2123245
uniprot id: G2RH16
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2110518
gene id: 578455:THITE_2110518
uniprot id: G2QT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

578455:THITE 2121463
gene id: 578455:THITE_2121463
uniprot id: G2REY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

578455:THITE 2123566
gene id: 578455:THITE_2123566
uniprot id: G2RHM2
names: Similarity
messages: Belongs to the BRX1 family.

578455:THITE 2122306
gene id: 578455:THITE_2122306
uniprot id: G2RCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2112352
gene id: 578455:THITE_2112352
uniprot id: G2QYL5
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

578455:THITE 122630
gene id: 578455:THITE_122630
uniprot id: G2RCG2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

578455:THITE 2110264
gene id: 578455:THITE_2110264
uniprot id: G2QS95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

578455:THITE 2119299
gene id: 578455:THITE_2119299
uniprot id: G2RBL1
names: Similarity
messages: Belongs to the SEN15 family.

578455:THITE 2086985
gene id: 578455:THITE_2086985
uniprot id: G2QZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

578455:THITE 2112979
gene id: 578455:THITE_2112979
uniprot id: G2R1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

578455:THITE 2107903
gene id: 578455:THITE_2107903
uniprot id: G2QW83
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

578455:THITE 2118669
gene id: 578455:THITE_2118669
uniprot id: G2RAK8
names: Similarity
messages: Belongs to the cullin family.

578455:THITE 2110538
gene id: 578455:THITE_2110538
uniprot id: G2QT81
names: Similarity
messages: Belongs to the FAH family.

578455:THITE 2115574
gene id: 578455:THITE_2115574
uniprot id: G2R4X5
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

578455:THITE 2080944
gene id: 578455:THITE_2080944
uniprot id: G2RAS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

578455:THITE 2109250
gene id: 578455:THITE_2109250
uniprot id: G2QUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

578455:THITE 2045531
gene id: 578455:THITE_2045531
uniprot id: G2QYS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRI1 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2107835
gene id: 578455:THITE_2107835
uniprot id: G2QVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

578455:THITE 2111827
gene id: 578455:THITE_2111827
uniprot id: G2R3N6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

578455:THITE 2117203
gene id: 578455:THITE_2117203
uniprot id: G2R7R2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 40832
gene id: 578455:THITE_40832
uniprot id: G2QRW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LOC1 family.
messages: Component of the 66S pre-ribosomal particle.
messages: Required for efficient assembly and nuclear export of the 60S ribosomal subunit.

578455:THITE 2123598
gene id: 578455:THITE_2123598
uniprot id: G2RHP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD2 family.
messages: Nucleus
messages: kinetochore
messages: spindle

578455:THITE 2116033
gene id: 578455:THITE_2116033
uniprot id: G2QZR9
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

578455:THITE 2109243
gene id: 578455:THITE_2109243
uniprot id: G2QUF2
names: Similarity
messages: Belongs to the actin family.

578455:THITE 2036335
gene id: 578455:THITE_2036335
uniprot id: G2QVS1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109377
gene id: 578455:THITE_2109377
uniprot id: G2QV90
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

578455:THITE 2024961
gene id: 578455:THITE_2024961
uniprot id: G2RA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 68668
gene id: 578455:THITE_68668
uniprot id: G2R382
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

578455:THITE 2080045
gene id: 578455:THITE_2080045
uniprot id: G2RBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining.
messages: Nucleus

578455:THITE 2121252
gene id: 578455:THITE_2121252
uniprot id: G2REQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 26742
gene id: 578455:THITE_26742
uniprot id: G2QTY6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108425
gene id: 578455:THITE_2108425
uniprot id: G2QR74
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

578455:THITE 2117762
gene id: 578455:THITE_2117762
uniprot id: G2R5K4
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

578455:THITE 2111546
gene id: 578455:THITE_2111546
uniprot id: G2R2R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

578455:THITE 2114110
gene id: 578455:THITE_2114110
uniprot id: G2QY89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

578455:THITE 2112976
gene id: 578455:THITE_2112976
uniprot id: G2R1G9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

578455:THITE 2123251
gene id: 578455:THITE_2123251
uniprot id: G2RH20
names: Similarity
messages: Belongs to the band 7/mec-2 family.

578455:THITE 2109778
gene id: 578455:THITE_2109778
uniprot id: G2QXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

578455:THITE 2116964
gene id: 578455:THITE_2116964
uniprot id: G2R7D2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

578455:THITE 2114057
gene id: 578455:THITE_2114057
uniprot id: G2R576
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

578455:THITE 55699
gene id: 578455:THITE_55699
uniprot id: G2R2X2
names: Similarity
messages: Belongs to the IUNH family.

578455:THITE 2110463
gene id: 578455:THITE_2110463
uniprot id: G2QT41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

578455:THITE 2109549
gene id: 578455:THITE_2109549
uniprot id: G2QWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

578455:THITE 2106137
gene id: 578455:THITE_2106137
uniprot id: G2QW45
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

578455:THITE 49921
gene id: 578455:THITE_49921
uniprot id: G2RGK5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2118655
gene id: 578455:THITE_2118655
uniprot id: G2RAK3
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

578455:THITE 2106401
gene id: 578455:THITE_2106401
uniprot id: G2QXL7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

578455:THITE 2118631
gene id: 578455:THITE_2118631
uniprot id: G2RAD7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 74712
gene id: 578455:THITE_74712
uniprot id: G2QUL7
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

578455:THITE 2075765
gene id: 578455:THITE_2075765
uniprot id: G2R5D4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2144003
gene id: 578455:THITE_2144003
uniprot id: G2R044
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2119067
gene id: 578455:THITE_2119067
uniprot id: G2RB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 111929
gene id: 578455:THITE_111929
uniprot id: G2R278
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2109490
gene id: 578455:THITE_2109490
uniprot id: G2QWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

578455:THITE 2107323
gene id: 578455:THITE_2107323
uniprot id: G2QTQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

578455:THITE 2121179
gene id: 578455:THITE_2121179
uniprot id: G2REM3
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

578455:THITE 2171332
gene id: 578455:THITE_2171332
uniprot id: G2RFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

578455:THITE 2117968
gene id: 578455:THITE_2117968
uniprot id: G2R699
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112271
gene id: 578455:THITE_2112271
uniprot id: G2QY66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

578455:THITE 2120278
gene id: 578455:THITE_2120278
uniprot id: G2RA33
names: Function
messages: Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.

578455:THITE 2111975
gene id: 578455:THITE_2111975
uniprot id: G2R459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2058411
gene id: 578455:THITE_2058411
uniprot id: G2RGL3
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2147597
gene id: 578455:THITE_2147597
uniprot id: G2RDX8
names: Similarity
messages: Belongs to the hexokinase family.

578455:THITE 2096857
gene id: 578455:THITE_2096857
uniprot id: G2RA32
names: Subcellular Location Annotation
messages: nuclear pore complex

578455:THITE 2117380
gene id: 578455:THITE_2117380
uniprot id: G2R7Z7
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

578455:THITE 2118062
gene id: 578455:THITE_2118062
uniprot id: G2R6U5
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

578455:THITE 2088904
gene id: 578455:THITE_2088904
uniprot id: G2R8K2
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2114834
gene id: 578455:THITE_2114834
uniprot id: G2R236
names: Similarity
messages: Belongs to the CoA-transferase III family.

578455:THITE 2110854
gene id: 578455:THITE_2110854
uniprot id: G2QUM0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2110159
gene id: 578455:THITE_2110159
uniprot id: G2QRT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2114611
gene id: 578455:THITE_2114611
uniprot id: G2R0L7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115738
gene id: 578455:THITE_2115738
uniprot id: G2R5E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nitrate reductase family.
messages: Homodimer.
messages: Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.

578455:THITE 2121614
gene id: 578455:THITE_2121614
uniprot id: G2RF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

578455:THITE 2114474
gene id: 578455:THITE_2114474
uniprot id: G2R019
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2112508
gene id: 578455:THITE_2112508
uniprot id: G2QZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

578455:THITE 2055209
gene id: 578455:THITE_2055209
uniprot id: G2RCV6
names: Similarity
messages: Belongs to the peptidase M20A family.

578455:THITE 2121684
gene id: 578455:THITE_2121684
uniprot id: G2RF73
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116663
gene id: 578455:THITE_2116663
uniprot id: G2R6Z1
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 127655
gene id: 578455:THITE_127655
uniprot id: G2QSS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2107246
gene id: 578455:THITE_2107246
uniprot id: G2QTB9
names: Similarity
messages: Belongs to the peptidase C48 family.

578455:THITE 2111447
gene id: 578455:THITE_2111447
uniprot id: G2R2C2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

578455:THITE 2040709
gene id: 578455:THITE_2040709
uniprot id: G2QSE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

578455:THITE 2118215
gene id: 578455:THITE_2118215
uniprot id: G2R936
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2061555
gene id: 578455:THITE_2061555
uniprot id: G2QQJ8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

578455:THITE 2106911
gene id: 578455:THITE_2106911
uniprot id: G2QRZ3
names: Similarity
messages: Belongs to the taxilin family.

578455:THITE 2122639
gene id: 578455:THITE_2122639
uniprot id: G2RDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

578455:THITE 2117453
gene id: 578455:THITE_2117453
uniprot id: G2R831
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

578455:THITE 2108382
gene id: 578455:THITE_2108382
uniprot id: G2QR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

578455:THITE 2049710
gene id: 578455:THITE_2049710
uniprot id: G2R788
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2118137
gene id: 578455:THITE_2118137
uniprot id: G2R745
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

578455:THITE 2120654
gene id: 578455:THITE_2120654
uniprot id: G2RD56
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

578455:THITE 2114393
gene id: 578455:THITE_2114393
uniprot id: G2QZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

578455:THITE 2119799
gene id: 578455:THITE_2119799
uniprot id: G2R8W8
names: Similarity
messages: Belongs to the PPP phosphatase family.

578455:THITE 2115337
gene id: 578455:THITE_2115337
uniprot id: G2R408
names: Similarity
messages: Belongs to the HGH1 family.

578455:THITE 2123426
gene id: 578455:THITE_2123426
uniprot id: G2RHD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

578455:THITE 2117940
gene id: 578455:THITE_2117940
uniprot id: G2R689
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2141268
gene id: 578455:THITE_2141268
uniprot id: G2QWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2118047
gene id: 578455:THITE_2118047
uniprot id: G2R6S9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2088833
gene id: 578455:THITE_2088833
uniprot id: G2R155
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

578455:THITE 2147589
gene id: 578455:THITE_2147589
uniprot id: G2RDW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

578455:THITE 2124559
gene id: 578455:THITE_2124559
uniprot id: G2RFZ3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

578455:THITE 63335
gene id: 578455:THITE_63335
uniprot id: G2QUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

578455:THITE 2112885
gene id: 578455:THITE_2112885
uniprot id: G2R0Y2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 60220
gene id: 578455:THITE_60220
uniprot id: G2RC58
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 72944
gene id: 578455:THITE_72944
uniprot id: G2RFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

578455:THITE 2115879
gene id: 578455:THITE_2115879
uniprot id: G2QYU7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

578455:THITE 2106520
gene id: 578455:THITE_2106520
uniprot id: G2QQJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

578455:THITE 165536
gene id: 578455:THITE_165536
uniprot id: G2R6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

578455:THITE 2118639
gene id: 578455:THITE_2118639
uniprot id: G2RAJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

578455:THITE 43393
gene id: 578455:THITE_43393
uniprot id: G2R8T9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2015229
gene id: 578455:THITE_2015229
uniprot id: G2QZQ8
names: Similarity
messages: Belongs to the tannase family.

578455:THITE 2115201
gene id: 578455:THITE_2115201
uniprot id: G2R3H9
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

578455:THITE 2146951
gene id: 578455:THITE_2146951
uniprot id: G2REC6
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

578455:THITE 2116756
gene id: 578455:THITE_2116756
uniprot id: G2R724
names: Similarity
messages: Belongs to the UPF0696 family.

578455:THITE 2041542
gene id: 578455:THITE_2041542
uniprot id: G2QSC6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122694
gene id: 578455:THITE_2122694
uniprot id: G2RDY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

578455:THITE 2110048
gene id: 578455:THITE_2110048
uniprot id: G2QRC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

578455:THITE 2023698
gene id: 578455:THITE_2023698
uniprot id: G2RBH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2111393
gene id: 578455:THITE_2111393
uniprot id: G2R2A3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2118965
gene id: 578455:THITE_2118965
uniprot id: G2RB45
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

578455:THITE 2086470
gene id: 578455:THITE_2086470
uniprot id: G2R2B0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2112530
gene id: 578455:THITE_2112530
uniprot id: G2QZF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

578455:THITE 2037256
gene id: 578455:THITE_2037256
uniprot id: G2QX03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

578455:THITE 2042530
gene id: 578455:THITE_2042530
uniprot id: G2QUK2
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2113318
gene id: 578455:THITE_2113318
uniprot id: G2R2F3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112228
gene id: 578455:THITE_2112228
uniprot id: G2QY43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway.
messages: Membrane
messages: Nucleus membrane
messages: perinuclear region

578455:THITE 2121480
gene id: 578455:THITE_2121480
uniprot id: G2REY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
messages: The GINS complex plays an essential role in the initiation of DNA replication.

578455:THITE 2119697
gene id: 578455:THITE_2119697
uniprot id: G2RC51
names: Similarity
messages: Belongs to the WD repeat mio family.

578455:THITE 56645
gene id: 578455:THITE_56645
uniprot id: G2R469
names: Similarity
messages: Belongs to the EFR3 family.

578455:THITE 2111731
gene id: 578455:THITE_2111731
uniprot id: G2R394
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117509
gene id: 578455:THITE_2117509
uniprot id: G2R861
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2120957
gene id: 578455:THITE_2120957
uniprot id: G2RE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

578455:THITE 2113856
gene id: 578455:THITE_2113856
uniprot id: G2R4B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.
messages: Mitochondrion matrix

578455:THITE 162912
gene id: 578455:THITE_162912
uniprot id: G2QSZ4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 130005
gene id: 578455:THITE_130005
uniprot id: G2QSZ0
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

578455:THITE 2120323
gene id: 578455:THITE_2120323
uniprot id: G2RA61
names: Subcellular Location Annotation
messages: Mitochondrion

578455:THITE 2113082
gene id: 578455:THITE_2113082
uniprot id: G2R1K3
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.

578455:THITE 2109351
gene id: 578455:THITE_2109351
uniprot id: G2QUW3
names: Similarity
messages: Belongs to the CDIP1/LITAF family.

578455:THITE 2108662
gene id: 578455:THITE_2108662
uniprot id: G2QS34
names: Similarity
messages: Belongs to the FMO family.

578455:THITE 2119894
gene id: 578455:THITE_2119894
uniprot id: G2R909
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

578455:THITE 2118599
gene id: 578455:THITE_2118599
uniprot id: G2RAC8
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

578455:THITE 2107421
gene id: 578455:THITE_2107421
uniprot id: G2QTU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

578455:THITE 2107570
gene id: 578455:THITE_2107570
uniprot id: G2QU99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

578455:THITE 2110954
gene id: 578455:THITE_2110954
uniprot id: G2QVH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan.
messages: Belongs to the glycosyl hydrolase 62 family.
messages: Secreted

578455:THITE 2057804
gene id: 578455:THITE_2057804
uniprot id: G2RCB1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106710
gene id: 578455:THITE_2106710
uniprot id: G2QRE8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117151
gene id: 578455:THITE_2117151
uniprot id: G2R7P7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123000
gene id: 578455:THITE_2123000
uniprot id: G2RGF9
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

578455:THITE 162750
gene id: 578455:THITE_162750
uniprot id: G2QQN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

578455:THITE 2054270
gene id: 578455:THITE_2054270
uniprot id: G2RA07
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

578455:THITE 2150588
gene id: 578455:THITE_2150588
uniprot id: G2QYD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

578455:THITE 165277
gene id: 578455:THITE_165277
uniprot id: G2R8A1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

578455:THITE 2142339
gene id: 578455:THITE_2142339
uniprot id: G2QTM1
names: Subcellular Location Annotation
messages: Peroxisome membrane

578455:THITE 2123746
gene id: 578455:THITE_2123746
uniprot id: G2RHV3
names: Similarity
messages: Belongs to the RNase PH family.

578455:THITE 2110755
gene id: 578455:THITE_2110755
uniprot id: G2QUH1
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2118954
gene id: 578455:THITE_2118954
uniprot id: G2RB39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: spindle

578455:THITE 2154006
gene id: 578455:THITE_2154006
uniprot id: G2QYJ1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108640
gene id: 578455:THITE_2108640
uniprot id: G2QS26
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2110989
gene id: 578455:THITE_2110989
uniprot id: G2QVW3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

578455:THITE 2107278
gene id: 578455:THITE_2107278
uniprot id: G2QTC8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

578455:THITE 2118711
gene id: 578455:THITE_2118711
uniprot id: G2RAM9
names: Subcellular Location Annotation
messages: Mitochondrion

578455:THITE 2106983
gene id: 578455:THITE_2106983
uniprot id: G2QSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2106565
gene id: 578455:THITE_2106565
uniprot id: G2QQL8
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

578455:THITE 2037799
gene id: 578455:THITE_2037799
uniprot id: G2QVZ7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 48594
gene id: 578455:THITE_48594
uniprot id: G2QTL6
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 40025
gene id: 578455:THITE_40025
uniprot id: G2QW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 76090
gene id: 578455:THITE_76090
uniprot id: G2R6U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2023945
gene id: 578455:THITE_2023945
uniprot id: G2R7M5
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2122839
gene id: 578455:THITE_2122839
uniprot id: G2REA9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

578455:THITE 2114052
gene id: 578455:THITE_2114052
uniprot id: G2R572
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

578455:THITE 2122151
gene id: 578455:THITE_2122151
uniprot id: G2RCA7
names: Similarity
messages: Belongs to the WrbA family.

578455:THITE 2108997
gene id: 578455:THITE_2108997
uniprot id: G2QT34
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2109409
gene id: 578455:THITE_2109409
uniprot id: G2QVC2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113241
gene id: 578455:THITE_2113241
uniprot id: G2R217
names: Similarity
messages: Belongs to the CBF/MAK21 family.

578455:THITE 2122797
gene id: 578455:THITE_2122797
uniprot id: G2RE86
names: Function
names: Similarity
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.

578455:THITE 110621
gene id: 578455:THITE_110621
uniprot id: G2R0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
messages: Nucleus

578455:THITE 2040070
gene id: 578455:THITE_2040070
uniprot id: G2QT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

578455:THITE 2131752
gene id: 578455:THITE_2131752
uniprot id: G2REY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 2106608
gene id: 578455:THITE_2106608
uniprot id: G2QQZ0
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interactions with other proteins and are required for lipid transport function.

578455:THITE 2149790
gene id: 578455:THITE_2149790
uniprot id: G2R460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

578455:THITE 2109366
gene id: 578455:THITE_2109366
uniprot id: G2QUX2
names: Similarity
names: Subunit
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
messages: Homotetramer.

578455:THITE 2117497
gene id: 578455:THITE_2117497
uniprot id: G2R856
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

578455:THITE 2040158
gene id: 578455:THITE_2040158
uniprot id: G2QUZ7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2081645
gene id: 578455:THITE_2081645
uniprot id: G2RF21
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

578455:THITE 2042642
gene id: 578455:THITE_2042642
uniprot id: G2QS88
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114539
gene id: 578455:THITE_2114539
uniprot id: G2R059
names: Similarity
messages: Belongs to the AFG1 ATPase family.

578455:THITE 2109343
gene id: 578455:THITE_2109343
uniprot id: G2QUV7
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.
messages: Belongs to the glycosyltransferase 77 family.

578455:THITE 2170357
gene id: 578455:THITE_2170357
uniprot id: G2R2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

578455:THITE 2024785
gene id: 578455:THITE_2024785
uniprot id: G2RHF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2114037
gene id: 578455:THITE_2114037
uniprot id: G2R565
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

578455:THITE 66300
gene id: 578455:THITE_66300
uniprot id: G2R5E3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

578455:THITE 2170109
gene id: 578455:THITE_2170109
uniprot id: G2R2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

578455:THITE 2115227
gene id: 578455:THITE_2115227
uniprot id: G2R3J1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122512
gene id: 578455:THITE_2122512
uniprot id: G2RDD0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

578455:THITE 2124179
gene id: 578455:THITE_2124179
uniprot id: G2RID4
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

578455:THITE 2047406
gene id: 578455:THITE_2047406
uniprot id: G2R4A0
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.

578455:THITE 2111890
gene id: 578455:THITE_2111890
uniprot id: G2R422
names: Similarity
messages: Belongs to the PrpD family.

578455:THITE 2112469
gene id: 578455:THITE_2112469
uniprot id: G2QZ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

578455:THITE 2112181
gene id: 578455:THITE_2112181
uniprot id: G2R538
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

578455:THITE 2046329
gene id: 578455:THITE_2046329
uniprot id: G2R530
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

578455:THITE 155704
gene id: 578455:THITE_155704
uniprot id: G2RB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

578455:THITE 2119424
gene id: 578455:THITE_2119424
uniprot id: G2RBS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

578455:THITE 2028140
gene id: 578455:THITE_2028140
uniprot id: G2QSV7
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

578455:THITE 2109783
gene id: 578455:THITE_2109783
uniprot id: G2QXZ0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

578455:THITE 2118650
gene id: 578455:THITE_2118650
uniprot id: G2RAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

578455:THITE 2142199
gene id: 578455:THITE_2142199
uniprot id: G2QS83
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2043513
gene id: 578455:THITE_2043513
uniprot id: G2R395
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2144327
gene id: 578455:THITE_2144327
uniprot id: G2R3Y7
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

578455:THITE 2123070
gene id: 578455:THITE_2123070
uniprot id: G2RGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2120518
gene id: 578455:THITE_2120518
uniprot id: G2RCK2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120695
gene id: 578455:THITE_2120695
uniprot id: G2RDF5
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

578455:THITE 2124248
gene id: 578455:THITE_2124248
uniprot id: G2RIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2117293
gene id: 578455:THITE_2117293
uniprot id: G2R7V4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115904
gene id: 578455:THITE_2115904
uniprot id: G2QYW4
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2113992
gene id: 578455:THITE_2113992
uniprot id: G2R547
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.

578455:THITE 2112650
gene id: 578455:THITE_2112650
uniprot id: G2QZY2
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2108431
gene id: 578455:THITE_2108431
uniprot id: G2QR76
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

578455:THITE 2085180
gene id: 578455:THITE_2085180
uniprot id: G2QU06
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2088327
gene id: 578455:THITE_2088327
uniprot id: G2R3Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2120584
gene id: 578455:THITE_2120584
uniprot id: G2RCM9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116034
gene id: 578455:THITE_2116034
uniprot id: G2QZS0
names: Similarity
messages: Belongs to the pantothenate synthetase family.

578455:THITE 2118536
gene id: 578455:THITE_2118536
uniprot id: G2RA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

578455:THITE 2106788
gene id: 578455:THITE_2106788
uniprot id: G2QRI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit and an accessory subunit.
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

578455:THITE 2119715
gene id: 578455:THITE_2119715
uniprot id: G2RC61
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

578455:THITE 2148210
gene id: 578455:THITE_2148210
uniprot id: G2RIB4
names: Function
names: Similarity
messages: Belongs to the WD repeat CIA1 family.
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

578455:THITE 2116861
gene id: 578455:THITE_2116861
uniprot id: G2R780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

578455:THITE 2121415
gene id: 578455:THITE_2121415
uniprot id: G2REW4
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

578455:THITE 2124584
gene id: 578455:THITE_2124584
uniprot id: G2RG08
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

578455:THITE 2121211
gene id: 578455:THITE_2121211
uniprot id: G2REN3
names: Similarity
messages: Belongs to the RMD1/sif2 family.

578455:THITE 2141906
gene id: 578455:THITE_2141906
uniprot id: G2QWE1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2171226
gene id: 578455:THITE_2171226
uniprot id: G2REM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane

578455:THITE 2119548
gene id: 578455:THITE_2119548
uniprot id: G2RBY2
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

578455:THITE 2113205
gene id: 578455:THITE_2113205
uniprot id: G2R205
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

578455:THITE 2121913
gene id: 578455:THITE_2121913
uniprot id: G2RFG9
names: Similarity
messages: Belongs to the AAA ATPase family.

578455:THITE 2119025
gene id: 578455:THITE_2119025
uniprot id: G2RB63
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 2153153
gene id: 578455:THITE_2153153
uniprot id: G2QRL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 2107811
gene id: 578455:THITE_2107811
uniprot id: G2QVJ9
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

578455:THITE 2115143
gene id: 578455:THITE_2115143
uniprot id: G2R3F6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2118525
gene id: 578455:THITE_2118525
uniprot id: G2RA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

578455:THITE 2121243
gene id: 578455:THITE_2121243
uniprot id: G2REP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

578455:THITE 2111629
gene id: 578455:THITE_2111629
uniprot id: G2R353
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

578455:THITE 2094212
gene id: 578455:THITE_2094212
uniprot id: G2QTW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

578455:THITE 128130
gene id: 578455:THITE_128130
uniprot id: G2R898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 161754
gene id: 578455:THITE_161754
uniprot id: G2R1K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2120356
gene id: 578455:THITE_2120356
uniprot id: G2RA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2108824
gene id: 578455:THITE_2108824
uniprot id: G2QSK3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

578455:THITE 2047170
gene id: 578455:THITE_2047170
uniprot id: G2R3D5
names: Similarity
messages: Belongs to the lysophospholipase family.

578455:THITE 2122302
gene id: 578455:THITE_2122302
uniprot id: G2RCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

578455:THITE 2120141
gene id: 578455:THITE_2120141
uniprot id: G2R9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

578455:THITE 2110324
gene id: 578455:THITE_2110324
uniprot id: G2QSM5
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

578455:THITE 2112871
gene id: 578455:THITE_2112871
uniprot id: G2R0X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

578455:THITE 2146609
gene id: 578455:THITE_2146609
uniprot id: G2RA60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

578455:THITE 70314
gene id: 578455:THITE_70314
uniprot id: G2QQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

578455:THITE 2107217
gene id: 578455:THITE_2107217
uniprot id: G2QTA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

578455:THITE 2171560
gene id: 578455:THITE_2171560
uniprot id: G2RHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: Vacuole membrane
messages: autophagosome membrane

578455:THITE 2108084
gene id: 578455:THITE_2108084
uniprot id: G2QXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2063817
gene id: 578455:THITE_2063817
uniprot id: G2R3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

578455:THITE 2113741
gene id: 578455:THITE_2113741
uniprot id: G2R472
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

578455:THITE 2112485
gene id: 578455:THITE_2112485
uniprot id: G2QZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Membrane
messages: Mitochondrion

578455:THITE 2119938
gene id: 578455:THITE_2119938
uniprot id: G2R979
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

578455:THITE 2115130
gene id: 578455:THITE_2115130
uniprot id: G2R342
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

578455:THITE 2112839
gene id: 578455:THITE_2112839
uniprot id: G2R0W4
names: Function
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

578455:THITE 2121111
gene id: 578455:THITE_2121111
uniprot id: G2REF5
names: Function
names: Similarity
messages: Belongs to the RRM RBM34 family.
messages: Involved in pre-25S rRNA processing.

578455:THITE 2115543
gene id: 578455:THITE_2115543
uniprot id: G2R4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium.

578455:THITE 2114017
gene id: 578455:THITE_2114017
uniprot id: G2R558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

578455:THITE 2169541
gene id: 578455:THITE_2169541
uniprot id: G2RIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 118431
gene id: 578455:THITE_118431
uniprot id: G2QYG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

578455:THITE 2114964
gene id: 578455:THITE_2114964
uniprot id: G2R2K9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

578455:THITE 152268
gene id: 578455:THITE_152268
uniprot id: G2QYP3
names: Similarity
messages: Belongs to the peptidase S8 family.

578455:THITE 2110073
gene id: 578455:THITE_2110073
uniprot id: G2QRE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

578455:THITE 2108304
gene id: 578455:THITE_2108304
uniprot id: G2QQR4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

578455:THITE 2070313
gene id: 578455:THITE_2070313
uniprot id: G2RC94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

578455:THITE 2171046
gene id: 578455:THITE_2171046
uniprot id: G2R9H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

578455:THITE 2143867
gene id: 578455:THITE_2143867
uniprot id: G2QYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

578455:THITE 2106221
gene id: 578455:THITE_2106221
uniprot id: G2QWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2116592
gene id: 578455:THITE_2116592
uniprot id: G2R6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2116949
gene id: 578455:THITE_2116949
uniprot id: G2R7C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2057447
gene id: 578455:THITE_2057447
uniprot id: G2REN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

578455:THITE 2108121
gene id: 578455:THITE_2108121
uniprot id: G2QXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

578455:THITE 2106899
gene id: 578455:THITE_2106899
uniprot id: G2QRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

578455:THITE 2091257
gene id: 578455:THITE_2091257
uniprot id: G2RAS4
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

578455:THITE 2114307
gene id: 578455:THITE_2114307
uniprot id: G2QZ66
names: Similarity
messages: Belongs to the PAT1 family.

578455:THITE 2122958
gene id: 578455:THITE_2122958
uniprot id: G2RGD9
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

578455:THITE 2117214
gene id: 578455:THITE_2117214
uniprot id: G2R7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

578455:THITE 2039513
gene id: 578455:THITE_2039513
uniprot id: G2QR00
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2119153
gene id: 578455:THITE_2119153
uniprot id: G2RBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2108537
gene id: 578455:THITE_2108537
uniprot id: G2QRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

578455:THITE 2109066
gene id: 578455:THITE_2109066
uniprot id: G2QTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

578455:THITE 2119193
gene id: 578455:THITE_2119193
uniprot id: G2RBG2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

578455:THITE 2114346
gene id: 578455:THITE_2114346
uniprot id: G2QZ93
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

578455:THITE 2123125
gene id: 578455:THITE_2123125
uniprot id: G2RGR4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

578455:THITE 2111107
gene id: 578455:THITE_2111107
uniprot id: G2QWJ6
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

578455:THITE 2070615
gene id: 578455:THITE_2070615
uniprot id: G2RDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2117505
gene id: 578455:THITE_2117505
uniprot id: G2R859
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106438
gene id: 578455:THITE_2106438
uniprot id: G2QXN3
names: Similarity
messages: Belongs to the cytochrome b5 family.

578455:THITE 2078408
gene id: 578455:THITE_2078408
uniprot id: G2R6F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

578455:THITE 2065850
gene id: 578455:THITE_2065850
uniprot id: G2R3T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

578455:THITE 2109261
gene id: 578455:THITE_2109261
uniprot id: G2QUG3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

578455:THITE 2114033
gene id: 578455:THITE_2114033
uniprot id: G2R564
names: Similarity
messages: Belongs to the hexokinase family.

578455:THITE 2115513
gene id: 578455:THITE_2115513
uniprot id: G2R4U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

578455:THITE 2169612
gene id: 578455:THITE_2169612
uniprot id: G2QQX0
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

578455:THITE 59635
gene id: 578455:THITE_59635
uniprot id: G2RAX1
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

578455:THITE 2121461
gene id: 578455:THITE_2121461
uniprot id: G2REX9
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

578455:THITE 2122165
gene id: 578455:THITE_2122165
uniprot id: G2RCB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2111119
gene id: 578455:THITE_2111119
uniprot id: G2QWK4
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 127862
gene id: 578455:THITE_127862
uniprot id: G2RHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

578455:THITE 2121595
gene id: 578455:THITE_2121595
uniprot id: G2RF36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

578455:THITE 2121720
gene id: 578455:THITE_2121720
uniprot id: G2RF85
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

578455:THITE 2114489
gene id: 578455:THITE_2114489
uniprot id: G2R032
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

578455:THITE 2124545
gene id: 578455:THITE_2124545
uniprot id: G2RFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

578455:THITE 2142483
gene id: 578455:THITE_2142483
uniprot id: G2QV16
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 120187
gene id: 578455:THITE_120187
uniprot id: G2R1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

578455:THITE 2123138
gene id: 578455:THITE_2123138
uniprot id: G2RGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

578455:THITE 2124519
gene id: 578455:THITE_2124519
uniprot id: G2RFX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 158106
gene id: 578455:THITE_158106
uniprot id: G2QRD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

578455:THITE 159383
gene id: 578455:THITE_159383
uniprot id: G2RIG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

578455:THITE 2108306
gene id: 578455:THITE_2108306
uniprot id: G2QQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

578455:THITE 2117002
gene id: 578455:THITE_2117002
uniprot id: G2R7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

578455:THITE 2108025
gene id: 578455:THITE_2108025
uniprot id: G2QWW5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

578455:THITE 2123640
gene id: 578455:THITE_2123640
uniprot id: G2RHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

578455:THITE 2116796
gene id: 578455:THITE_2116796
uniprot id: G2R756
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

578455:THITE 2116585
gene id: 578455:THITE_2116585
uniprot id: G2R6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

578455:THITE 2110899
gene id: 578455:THITE_2110899
uniprot id: G2QV02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

578455:THITE 2108357
gene id: 578455:THITE_2108357
uniprot id: G2QR51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2120354
gene id: 578455:THITE_2120354
uniprot id: G2RA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

578455:THITE 2124498
gene id: 578455:THITE_2124498
uniprot id: G2RFW5
names: Similarity
messages: Belongs to the group II decarboxylase family.

578455:THITE 2146203
gene id: 578455:THITE_2146203
uniprot id: G2RBM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2107289
gene id: 578455:THITE_2107289
uniprot id: G2QTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

578455:THITE 2115476
gene id: 578455:THITE_2115476
uniprot id: G2R4H4
names: Similarity
messages: Belongs to the peptidase C12 family.

578455:THITE 109555
gene id: 578455:THITE_109555
uniprot id: G2RGH7
names: Similarity
messages: Belongs to the frataxin family.

578455:THITE 2107695
gene id: 578455:THITE_2107695
uniprot id: G2QUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

578455:THITE 2171724
gene id: 578455:THITE_2171724
uniprot id: G2RGH6
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

578455:THITE 2143832
gene id: 578455:THITE_2143832
uniprot id: G2QYB8
names: Similarity
messages: Belongs to the nuclease type I family.

578455:THITE 2114858
gene id: 578455:THITE_2114858
uniprot id: G2R252
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

578455:THITE 2112803
gene id: 578455:THITE_2112803
uniprot id: G2R0V1
names: Similarity
messages: Belongs to the OSBP family.

578455:THITE 2113922
gene id: 578455:THITE_2113922
uniprot id: G2R4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

578455:THITE 2146465
gene id: 578455:THITE_2146465
uniprot id: G2R996
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2109605
gene id: 578455:THITE_2109605
uniprot id: G2QX09
names: Similarity
messages: Belongs to the AHA1 family.

578455:THITE 2117947
gene id: 578455:THITE_2117947
uniprot id: G2R691
names: Similarity
messages: Belongs to the APC1 family.

578455:THITE 2114126
gene id: 578455:THITE_2114126
uniprot id: G2QY94
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

578455:THITE 2108513
gene id: 578455:THITE_2108513
uniprot id: G2QRM4
names: Similarity
messages: Belongs to the MAK16 family.

578455:THITE 2113195
gene id: 578455:THITE_2113195
uniprot id: G2R200
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

578455:THITE 2118236
gene id: 578455:THITE_2118236
uniprot id: G2R951
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

578455:THITE 2169158
gene id: 578455:THITE_2169158
uniprot id: G2QXM3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

578455:THITE 124911
gene id: 578455:THITE_124911
uniprot id: G2R6J2
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2116698
gene id: 578455:THITE_2116698
uniprot id: G2R704
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

578455:THITE 2169864
gene id: 578455:THITE_2169864
uniprot id: G2R349
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

578455:THITE 2169592
gene id: 578455:THITE_2169592
uniprot id: G2QXY9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

578455:THITE 2122704
gene id: 578455:THITE_2122704
uniprot id: G2RDZ0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2113910
gene id: 578455:THITE_2113910
uniprot id: G2R4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

578455:THITE 2155033
gene id: 578455:THITE_2155033
uniprot id: G2R732
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2112913
gene id: 578455:THITE_2112913
uniprot id: G2R0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

578455:THITE 2130382
gene id: 578455:THITE_2130382
uniprot id: G2R9C1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2119121
gene id: 578455:THITE_2119121
uniprot id: G2RBD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Nucleus

578455:THITE 2121012
gene id: 578455:THITE_2121012
uniprot id: G2RE58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

578455:THITE 2115577
gene id: 578455:THITE_2115577
uniprot id: G2R4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus

578455:THITE 2114837
gene id: 578455:THITE_2114837
uniprot id: G2R242
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

578455:THITE 2169241
gene id: 578455:THITE_2169241
uniprot id: G2QSG3
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

578455:THITE 2108936
gene id: 578455:THITE_2108936
uniprot id: G2QT13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24 family.
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

578455:THITE 2116696
gene id: 578455:THITE_2116696
uniprot id: G2R703
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

578455:THITE 2106674
gene id: 578455:THITE_2106674
uniprot id: G2QR20
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

578455:THITE 2115551
gene id: 578455:THITE_2115551
uniprot id: G2R4W4
names: Similarity
messages: Belongs to the cytochrome b5 family.

578455:THITE 11301
gene id: 578455:THITE_11301
uniprot id: G2R7Z1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2077933
gene id: 578455:THITE_2077933
uniprot id: G2QZQ6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

578455:THITE 2116055
gene id: 578455:THITE_2116055
uniprot id: G2QZT1
names: Similarity
messages: Belongs to the SGT family.

578455:THITE 2110514
gene id: 578455:THITE_2110514
uniprot id: G2QT72
names: Similarity
messages: Belongs to the thioesterase PaaI family.

578455:THITE 64605
gene id: 578455:THITE_64605
uniprot id: G2RG79
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122605
gene id: 578455:THITE_2122605
uniprot id: G2RDM8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

578455:THITE 2117930
gene id: 578455:THITE_2117930
uniprot id: G2R683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Nucleus

578455:THITE 125239
gene id: 578455:THITE_125239
uniprot id: G2R7W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2113189
gene id: 578455:THITE_2113189
uniprot id: G2R1Z7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2079729
gene id: 578455:THITE_2079729
uniprot id: G2RAD0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

578455:THITE 62596
gene id: 578455:THITE_62596
uniprot id: G2QXZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.

578455:THITE 2116112
gene id: 578455:THITE_2116112
uniprot id: G2QZW2
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

578455:THITE 2095844
gene id: 578455:THITE_2095844
uniprot id: G2QZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2063035
gene id: 578455:THITE_2063035
uniprot id: G2QTE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

578455:THITE 2117977
gene id: 578455:THITE_2117977
uniprot id: G2R6A7
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 72992
gene id: 578455:THITE_72992
uniprot id: G2RF95
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit.

578455:THITE 2107076
gene id: 578455:THITE_2107076
uniprot id: G2QSG9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2155002
gene id: 578455:THITE_2155002
uniprot id: G2R6S3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111190
gene id: 578455:THITE_2111190
uniprot id: G2R1B8
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2121402
gene id: 578455:THITE_2121402
uniprot id: G2REV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

578455:THITE 2122911
gene id: 578455:THITE_2122911
uniprot id: G2RGB3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123949
gene id: 578455:THITE_2123949
uniprot id: G2RI42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

578455:THITE 2062142
gene id: 578455:THITE_2062142
uniprot id: G2QU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

578455:THITE 2107789
gene id: 578455:THITE_2107789
uniprot id: G2QV74
names: Similarity
messages: Belongs to the NOP10 family.

578455:THITE 2107786
gene id: 578455:THITE_2107786
uniprot id: G2QV73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

578455:THITE 2109828
gene id: 578455:THITE_2109828
uniprot id: G2QY06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

578455:THITE 125668
gene id: 578455:THITE_125668
uniprot id: G2R8K5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2116127
gene id: 578455:THITE_2116127
uniprot id: G2R074
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2119114
gene id: 578455:THITE_2119114
uniprot id: G2RBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

578455:THITE 2107280
gene id: 578455:THITE_2107280
uniprot id: G2QTC9
names: Function
names: Subunit
messages: Associates with DNA double-strand breaks.
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.

578455:THITE 2116185
gene id: 578455:THITE_2116185
uniprot id: G2R0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

578455:THITE 2110069
gene id: 578455:THITE_2110069
uniprot id: G2QRD9
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 163285
gene id: 578455:THITE_163285
uniprot id: G2RBK8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115059
gene id: 578455:THITE_2115059
uniprot id: G2R304
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

578455:THITE 115243
gene id: 578455:THITE_115243
uniprot id: G2RDT8
names: Similarity
messages: Belongs to the acetyltransferase family. GCN5 subfamily.

578455:THITE 2114009
gene id: 578455:THITE_2114009
uniprot id: G2R553
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

578455:THITE 156710
gene id: 578455:THITE_156710
uniprot id: G2RD32
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 20881
gene id: 578455:THITE_20881
uniprot id: G2QYT6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2121399
gene id: 578455:THITE_2121399
uniprot id: G2REV8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2109486
gene id: 578455:THITE_2109486
uniprot id: G2QWB2
names: Function
names: Similarity
messages: Belongs to the BYE1 family.
messages: Negative regulator of transcription elongation.

578455:THITE 2113512
gene id: 578455:THITE_2113512
uniprot id: G2R2Z1
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

578455:THITE 2114341
gene id: 578455:THITE_2114341
uniprot id: G2QZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NUF2 family.
messages: Nucleus
messages: kinetochore

578455:THITE 2109612
gene id: 578455:THITE_2109612
uniprot id: G2QX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

578455:THITE 2112511
gene id: 578455:THITE_2112511
uniprot id: G2QZ42
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

578455:THITE 2145487
gene id: 578455:THITE_2145487
uniprot id: G2R5L6
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

578455:THITE 2118762
gene id: 578455:THITE_2118762
uniprot id: G2RAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2112890
gene id: 578455:THITE_2112890
uniprot id: G2R0Y5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

578455:THITE 2107910
gene id: 578455:THITE_2107910
uniprot id: G2QW86
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2110926
gene id: 578455:THITE_2110926
uniprot id: G2QVF4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111657
gene id: 578455:THITE_2111657
uniprot id: G2R362
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2084675
gene id: 578455:THITE_2084675
uniprot id: G2QXD9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

578455:THITE 57831
gene id: 578455:THITE_57831
uniprot id: G2QSV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

578455:THITE 2107701
gene id: 578455:THITE_2107701
uniprot id: G2QUQ9
names: Similarity
messages: Belongs to the TRM112 family.

578455:THITE 2110243
gene id: 578455:THITE_2110243
uniprot id: G2QS82
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2121860
gene id: 578455:THITE_2121860
uniprot id: G2RFE3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2119823
gene id: 578455:THITE_2119823
uniprot id: G2R8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

578455:THITE 2049425
gene id: 578455:THITE_2049425
uniprot id: G2R5P8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

578455:THITE 2125101
gene id: 578455:THITE_2125101
uniprot id: G2QQM2
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

578455:THITE 2169904
gene id: 578455:THITE_2169904
uniprot id: G2R3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

578455:THITE 136083
gene id: 578455:THITE_136083
uniprot id: G2RIC9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2049700
gene id: 578455:THITE_2049700
uniprot id: G2R5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 2170684
gene id: 578455:THITE_2170684
uniprot id: G2R854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2113998
gene id: 578455:THITE_2113998
uniprot id: G2R549
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

578455:THITE 2114040
gene id: 578455:THITE_2114040
uniprot id: G2R567
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

578455:THITE 2124116
gene id: 578455:THITE_2124116
uniprot id: G2RIB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

578455:THITE 2117256
gene id: 578455:THITE_2117256
uniprot id: G2R7T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

578455:THITE 2112792
gene id: 578455:THITE_2112792
uniprot id: G2R0H3
names: Similarity
messages: Belongs to the hexokinase family.

578455:THITE 2109960
gene id: 578455:THITE_2109960
uniprot id: G2QQX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

578455:THITE 2106676
gene id: 578455:THITE_2106676
uniprot id: G2QR21
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

578455:THITE 2059814
gene id: 578455:THITE_2059814
uniprot id: G2RGW5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2027507
gene id: 578455:THITE_2027507
uniprot id: G2RFV6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122855
gene id: 578455:THITE_2122855
uniprot id: G2REH4
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

578455:THITE 2116667
gene id: 578455:THITE_2116667
uniprot id: G2R6Z2
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

578455:THITE 2106867
gene id: 578455:THITE_2106867
uniprot id: G2QRW8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.

578455:THITE 2122377
gene id: 578455:THITE_2122377
uniprot id: G2RD01
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

578455:THITE 2110255
gene id: 578455:THITE_2110255
uniprot id: G2QS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

578455:THITE 2119778
gene id: 578455:THITE_2119778
uniprot id: G2R8V8
names: Similarity
messages: Belongs to the CBP3 family.

578455:THITE 2122635
gene id: 578455:THITE_2122635
uniprot id: G2RDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the END3 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: Membrane
messages: actin patch

578455:THITE 2112541
gene id: 578455:THITE_2112541
uniprot id: G2QZG1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2124259
gene id: 578455:THITE_2124259
uniprot id: G2RIG1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

578455:THITE 2123089
gene id: 578455:THITE_2123089
uniprot id: G2RGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

578455:THITE 37268
gene id: 578455:THITE_37268
uniprot id: G2R2F0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2109338
gene id: 578455:THITE_2109338
uniprot id: G2QUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2123538
gene id: 578455:THITE_2123538
uniprot id: G2RHL2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108385
gene id: 578455:THITE_2108385
uniprot id: G2QR59
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

578455:THITE 68116
gene id: 578455:THITE_68116
uniprot id: G2QZW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

578455:THITE 23764
gene id: 578455:THITE_23764
uniprot id: G2R2N1
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.

578455:THITE 2038066
gene id: 578455:THITE_2038066
uniprot id: G2QRP3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

578455:THITE 2112678
gene id: 578455:THITE_2112678
uniprot id: G2QZZ8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2110120
gene id: 578455:THITE_2110120
uniprot id: G2QRS0
names: Similarity
messages: Belongs to the terpene synthase family.

578455:THITE 115563
gene id: 578455:THITE_115563
uniprot id: G2QWD3
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

578455:THITE 2107141
gene id: 578455:THITE_2107141
uniprot id: G2QSW2
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

578455:THITE 2110273
gene id: 578455:THITE_2110273
uniprot id: G2QS98
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2034879
gene id: 578455:THITE_2034879
uniprot id: G2QRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.

578455:THITE 2115933
gene id: 578455:THITE_2115933
uniprot id: G2QYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

578455:THITE 2119626
gene id: 578455:THITE_2119626
uniprot id: G2RC19
names: Similarity
messages: Belongs to the NSRP1 family.

578455:THITE 2112518
gene id: 578455:THITE_2112518
uniprot id: G2QZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

578455:THITE 2113711
gene id: 578455:THITE_2113711
uniprot id: G2R3U7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

578455:THITE 2107826
gene id: 578455:THITE_2107826
uniprot id: G2QVL1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112528
gene id: 578455:THITE_2112528
uniprot id: G2QZF7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 163739
gene id: 578455:THITE_163739
uniprot id: G2RCQ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

578455:THITE 2117067
gene id: 578455:THITE_2117067
uniprot id: G2R7I8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2086830
gene id: 578455:THITE_2086830
uniprot id: G2QY55
names: Similarity
messages: Belongs to the diacylglycerol acyltransferase family.

578455:THITE 2130018
gene id: 578455:THITE_2130018
uniprot id: G2R8P9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2123292
gene id: 578455:THITE_2123292
uniprot id: G2RH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

578455:THITE 2049779
gene id: 578455:THITE_2049779
uniprot id: G2R6D1
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Monomer.

578455:THITE 135798
gene id: 578455:THITE_135798
uniprot id: G2RGC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

578455:THITE 135209
gene id: 578455:THITE_135209
uniprot id: G2RET2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2119285
gene id: 578455:THITE_2119285
uniprot id: G2RBK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.

578455:THITE 2156598
gene id: 578455:THITE_2156598
uniprot id: G2RHA3
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus inner membrane

578455:THITE 2116134
gene id: 578455:THITE_2116134
uniprot id: G2R075
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

578455:THITE 2112992
gene id: 578455:THITE_2112992
uniprot id: G2R1H4
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2108841
gene id: 578455:THITE_2108841
uniprot id: G2QSL1
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

578455:THITE 71782
gene id: 578455:THITE_71782
uniprot id: G2RC31
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

578455:THITE 2117669
gene id: 578455:THITE_2117669
uniprot id: G2R8H4
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

578455:THITE 2123899
gene id: 578455:THITE_2123899
uniprot id: G2RI21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

578455:THITE 2141149
gene id: 578455:THITE_2141149
uniprot id: G2QV39
names: Similarity
messages: Belongs to the TOP6A family.

578455:THITE 2124288
gene id: 578455:THITE_2124288
uniprot id: G2RIH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

578455:THITE 125074
gene id: 578455:THITE_125074
uniprot id: G2R8M6
names: Similarity
messages: Belongs to the chloroperoxidase family.

578455:THITE 2119187
gene id: 578455:THITE_2119187
uniprot id: G2RBF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2042100
gene id: 578455:THITE_2042100
uniprot id: G2QUC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

578455:THITE 2123266
gene id: 578455:THITE_2123266
uniprot id: G2RH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

578455:THITE 2121288
gene id: 578455:THITE_2121288
uniprot id: G2RER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

578455:THITE 2067623
gene id: 578455:THITE_2067623
uniprot id: G2R672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

578455:THITE 2113844
gene id: 578455:THITE_2113844
uniprot id: G2R4A7
names: Subcellular Location Annotation
messages: cytoskeleton

578455:THITE 2120537
gene id: 578455:THITE_2120537
uniprot id: G2RCK9
names: Function
names: Similarity
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.

578455:THITE 2170099
gene id: 578455:THITE_2170099
uniprot id: G2R201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

578455:THITE 2111280
gene id: 578455:THITE_2111280
uniprot id: G2R1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

578455:THITE 116134
gene id: 578455:THITE_116134
uniprot id: G2QUK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Nucleus

578455:THITE 2029354
gene id: 578455:THITE_2029354
uniprot id: G2R886
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117187
gene id: 578455:THITE_2117187
uniprot id: G2R7Q7
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

578455:THITE 2038147
gene id: 578455:THITE_2038147
uniprot id: G2QTF6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117019
gene id: 578455:THITE_2117019
uniprot id: G2R7G5
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

578455:THITE 2110821
gene id: 578455:THITE_2110821
uniprot id: G2QUK1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2114551
gene id: 578455:THITE_2114551
uniprot id: G2R064
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

578455:THITE 2080461
gene id: 578455:THITE_2080461
uniprot id: G2R8V7
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

578455:THITE 72629
gene id: 578455:THITE_72629
uniprot id: G2RCT3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2123991
gene id: 578455:THITE_2123991
uniprot id: G2RI56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2112805
gene id: 578455:THITE_2112805
uniprot id: G2R0V2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

578455:THITE 2088100
gene id: 578455:THITE_2088100
uniprot id: G2R232
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2112401
gene id: 578455:THITE_2112401
uniprot id: G2QYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Membrane
messages: Vacuole membrane

578455:THITE 2106375
gene id: 578455:THITE_2106375
uniprot id: G2QXA0
names: Similarity
messages: Belongs to the Cdt1 family.

578455:THITE 134147
gene id: 578455:THITE_134147
uniprot id: G2QS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2108366
gene id: 578455:THITE_2108366
uniprot id: G2QR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

578455:THITE 2055331
gene id: 578455:THITE_2055331
uniprot id: G2RD79
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2109296
gene id: 578455:THITE_2109296
uniprot id: G2RIC5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121289
gene id: 578455:THITE_2121289
uniprot id: G2RER6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

578455:THITE 2079896
gene id: 578455:THITE_2079896
uniprot id: G2RAZ0
names: Similarity
messages: Belongs to the CWC21 family.

578455:THITE 2106556
gene id: 578455:THITE_2106556
uniprot id: G2QQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2111660
gene id: 578455:THITE_2111660
uniprot id: G2R364
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112782
gene id: 578455:THITE_2112782
uniprot id: G2R0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

578455:THITE 2171059
gene id: 578455:THITE_2171059
uniprot id: G2R9K7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

578455:THITE 2119040
gene id: 578455:THITE_2119040
uniprot id: G2RB73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2110333
gene id: 578455:THITE_2110333
uniprot id: G2QSM9
names: Similarity
messages: Belongs to the FBPase class 1 family.

578455:THITE 126586
gene id: 578455:THITE_126586
uniprot id: G2QTA6
names: Similarity
messages: Belongs to the NDK family.

578455:THITE 124733
gene id: 578455:THITE_124733
uniprot id: G2RG83
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

578455:THITE 2170481
gene id: 578455:THITE_2170481
uniprot id: G2QYW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2120876
gene id: 578455:THITE_2120876
uniprot id: G2RDV3
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

578455:THITE 2122653
gene id: 578455:THITE_2122653
uniprot id: G2RDQ0
names: Function
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.

578455:THITE 2145571
gene id: 578455:THITE_2145571
uniprot id: G2R679
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2032291
gene id: 578455:THITE_2032291
uniprot id: G2QYF7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2051832
gene id: 578455:THITE_2051832
uniprot id: G2R5H8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123681
gene id: 578455:THITE_2123681
uniprot id: G2RHS6
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

578455:THITE 2121434
gene id: 578455:THITE_2121434
uniprot id: G2REW9
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

578455:THITE 2109840
gene id: 578455:THITE_2109840
uniprot id: G2QY14
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

578455:THITE 2117012
gene id: 578455:THITE_2117012
uniprot id: G2R7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

578455:THITE 2057738
gene id: 578455:THITE_2057738
uniprot id: G2REL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

578455:THITE 2155778
gene id: 578455:THITE_2155778
uniprot id: G2R968
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

578455:THITE 2147949
gene id: 578455:THITE_2147949
uniprot id: G2RHG7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121927
gene id: 578455:THITE_2121927
uniprot id: G2RFH5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

578455:THITE 2112626
gene id: 578455:THITE_2112626
uniprot id: G2QZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2044103
gene id: 578455:THITE_2044103
uniprot id: G2R3M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

578455:THITE 2116037
gene id: 578455:THITE_2116037
uniprot id: G2QZS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

578455:THITE 2113474
gene id: 578455:THITE_2113474
uniprot id: G2R2X5
names: Similarity
messages: Belongs to the glutaredoxin family.

578455:THITE 2120059
gene id: 578455:THITE_2120059
uniprot id: G2R9I6
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

578455:THITE 2114323
gene id: 578455:THITE_2114323
uniprot id: G2QZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.

578455:THITE 123322
gene id: 578455:THITE_123322
uniprot id: G2QV98
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2128646
gene id: 578455:THITE_2128646
uniprot id: G2R223
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

578455:THITE 18434
gene id: 578455:THITE_18434
uniprot id: G2QVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

578455:THITE 2119070
gene id: 578455:THITE_2119070
uniprot id: G2RB97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Palmitoyltransferase specific for casein kinase 1.
messages: The DHHC domain is required for palmitoyltransferase activity.

578455:THITE 2112381
gene id: 578455:THITE_2112381
uniprot id: G2QYM7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

578455:THITE 2078736
gene id: 578455:THITE_2078736
uniprot id: G2R7J9
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Belongs to the tannase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

578455:THITE 2121145
gene id: 578455:THITE_2121145
uniprot id: G2REG8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2037905
gene id: 578455:THITE_2037905
uniprot id: G2QQN0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2141204
gene id: 578455:THITE_2141204
uniprot id: G2QVN6
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

578455:THITE 2107139
gene id: 578455:THITE_2107139
uniprot id: G2QSW1
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 115391
gene id: 578455:THITE_115391
uniprot id: G2RCT7
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 2123958
gene id: 578455:THITE_2123958
uniprot id: G2RI46
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

578455:THITE 2050713
gene id: 578455:THITE_2050713
uniprot id: G2R750
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

578455:THITE 2119622
gene id: 578455:THITE_2119622
uniprot id: G2RC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

578455:THITE 2114333
gene id: 578455:THITE_2114333
uniprot id: G2QZ76
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

578455:THITE 2142370
gene id: 578455:THITE_2142370
uniprot id: G2QU24
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 36500
gene id: 578455:THITE_36500
uniprot id: G2R2G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

578455:THITE 162029
gene id: 578455:THITE_162029
uniprot id: G2R454
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

578455:THITE 2083924
gene id: 578455:THITE_2083924
uniprot id: G2QQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2108922
gene id: 578455:THITE_2108922
uniprot id: G2QT06
names: Similarity
messages: Belongs to the glutamine synthetase family.

578455:THITE 2124608
gene id: 578455:THITE_2124608
uniprot id: G2RG20
names: Similarity
messages: Belongs to the group II decarboxylase family.

578455:THITE 13076
gene id: 578455:THITE_13076
uniprot id: G2RA36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

578455:THITE 2108763
gene id: 578455:THITE_2108763
uniprot id: G2QSH8
names: Similarity
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

578455:THITE 2142184
gene id: 578455:THITE_2142184
uniprot id: G2QS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

578455:THITE 2169762
gene id: 578455:THITE_2169762
uniprot id: G2QWG6
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

578455:THITE 2148444
gene id: 578455:THITE_2148444
uniprot id: G2RG91
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115057
gene id: 578455:THITE_2115057
uniprot id: G2R303
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

578455:THITE 2121875
gene id: 578455:THITE_2121875
uniprot id: G2RFE9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: GTPase-activating protein for the ADP ribosylation factor family.

578455:THITE 2115075
gene id: 578455:THITE_2115075
uniprot id: G2R312
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 2108409
gene id: 578455:THITE_2108409
uniprot id: G2QR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2107182
gene id: 578455:THITE_2107182
uniprot id: G2QT91
names: Similarity
messages: Belongs to the serine esterase family.

578455:THITE 2114569
gene id: 578455:THITE_2114569
uniprot id: G2R0J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

578455:THITE 2113289
gene id: 578455:THITE_2113289
uniprot id: G2R2E1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2041678
gene id: 578455:THITE_2041678
uniprot id: G2QUC3
names: Similarity
messages: Belongs to the chloroperoxidase family.

578455:THITE 2113335
gene id: 578455:THITE_2113335
uniprot id: G2R2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

578455:THITE 2110382
gene id: 578455:THITE_2110382
uniprot id: G2QSQ1
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

578455:THITE 2129735
gene id: 578455:THITE_2129735
uniprot id: G2R7L2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2116952
gene id: 578455:THITE_2116952
uniprot id: G2R7C8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

578455:THITE 2113507
gene id: 578455:THITE_2113507
uniprot id: G2R2Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

578455:THITE 2054848
gene id: 578455:THITE_2054848
uniprot id: G2R9N5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2044283
gene id: 578455:THITE_2044283
uniprot id: G2R157
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

578455:THITE 2096374
gene id: 578455:THITE_2096374
uniprot id: G2R960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 22 family.
messages: Nucleus

578455:THITE 2087724
gene id: 578455:THITE_2087724
uniprot id: G2QYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anthrone oxygenase family.
messages: Membrane

578455:THITE 2109034
gene id: 578455:THITE_2109034
uniprot id: G2QTF7
names: Similarity
messages: Belongs to the peptidase C19 family.

578455:THITE 124995
gene id: 578455:THITE_124995
uniprot id: G2R5W0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

578455:THITE 2120291
gene id: 578455:THITE_2120291
uniprot id: G2RA40
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2108053
gene id: 578455:THITE_2108053
uniprot id: G2QXD3
names: Similarity
messages: Belongs to the FHIP family.

578455:THITE 2072362
gene id: 578455:THITE_2072362
uniprot id: G2QQV7
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2122100
gene id: 578455:THITE_2122100
uniprot id: G2RC85
names: Similarity
messages: Belongs to the VPS8 family.

578455:THITE 58765
gene id: 578455:THITE_58765
uniprot id: G2QRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity). The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity). Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1).
messages: Nucleus

578455:THITE 2111324
gene id: 578455:THITE_2111324
uniprot id: G2R1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2106335
gene id: 578455:THITE_2106335
uniprot id: G2QX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

578455:THITE 2115184
gene id: 578455:THITE_2115184
uniprot id: G2R3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

578455:THITE 159326
gene id: 578455:THITE_159326
uniprot id: G2RIA9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107766
gene id: 578455:THITE_2107766
uniprot id: G2QV65
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: extracellular space

578455:THITE 2120948
gene id: 578455:THITE_2120948
uniprot id: G2RE35
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2043159
gene id: 578455:THITE_2043159
uniprot id: G2QX04
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

578455:THITE 2106655
gene id: 578455:THITE_2106655
uniprot id: G2QR11
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

578455:THITE 2116840
gene id: 578455:THITE_2116840
uniprot id: G2R773
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

578455:THITE 132564
gene id: 578455:THITE_132564
uniprot id: G2R4W3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2110511
gene id: 578455:THITE_2110511
uniprot id: G2QT70
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

578455:THITE 2124772
gene id: 578455:THITE_2124772
uniprot id: G2RGL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2118141
gene id: 578455:THITE_2118141
uniprot id: G2R749
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2055151
gene id: 578455:THITE_2055151
uniprot id: G2RBM3
names: Function
names: Similarity
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.

578455:THITE 2042844
gene id: 578455:THITE_2042844
uniprot id: G2QV64
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2093193
gene id: 578455:THITE_2093193
uniprot id: G2RFU5
names: Similarity
messages: Belongs to the FGGY kinase family.

578455:THITE 2115321
gene id: 578455:THITE_2115321
uniprot id: G2R3Z6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

578455:THITE 2120746
gene id: 578455:THITE_2120746
uniprot id: G2RDJ2
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

578455:THITE 2044100
gene id: 578455:THITE_2044100
uniprot id: G2QYN2
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

578455:THITE 2108253
gene id: 578455:THITE_2108253
uniprot id: G2QQP9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

578455:THITE 2120398
gene id: 578455:THITE_2120398
uniprot id: G2RAH4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120300
gene id: 578455:THITE_2120300
uniprot id: G2RA45
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2060368
gene id: 578455:THITE_2060368
uniprot id: G2RFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2088638
gene id: 578455:THITE_2088638
uniprot id: G2QZC3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Confers resistance to H(2)O(2) in hyphae. May play an antioxidative role in fungal defense against the host-produced H(2)O(2) (oxidative burst) at the early stage of plant infection.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer; disulfide-linked.
messages: Secreted

578455:THITE 2120384
gene id: 578455:THITE_2120384
uniprot id: G2RAG3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

578455:THITE 124055
gene id: 578455:THITE_124055
uniprot id: G2QX45
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2117015
gene id: 578455:THITE_2117015
uniprot id: G2R7G3
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

578455:THITE 2143523
gene id: 578455:THITE_2143523
uniprot id: G2R2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2115859
gene id: 578455:THITE_2115859
uniprot id: G2QYI6
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

578455:THITE 2108557
gene id: 578455:THITE_2108557
uniprot id: G2QRN8
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2116120
gene id: 578455:THITE_2116120
uniprot id: G2R072
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

578455:THITE 2146331
gene id: 578455:THITE_2146331
uniprot id: G2RC30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

578455:THITE 2122990
gene id: 578455:THITE_2122990
uniprot id: G2RGF5
names: Similarity
messages: Belongs to the fructosamine kinase family.

578455:THITE 128637
gene id: 578455:THITE_128637
uniprot id: G2R0M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

578455:THITE 2123390
gene id: 578455:THITE_2123390
uniprot id: G2RHA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

578455:THITE 2124747
gene id: 578455:THITE_2124747
uniprot id: G2RGI1
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

578455:THITE 2110353
gene id: 578455:THITE_2110353
uniprot id: G2QSN8
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

578455:THITE 2116044
gene id: 578455:THITE_2116044
uniprot id: G2QZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

578455:THITE 2073178
gene id: 578455:THITE_2073178
uniprot id: G2QQK2
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

578455:THITE 161129
gene id: 578455:THITE_161129
uniprot id: G2R5C5
names: Similarity
messages: Belongs to the Rab GDI family.

578455:THITE 2146152
gene id: 578455:THITE_2146152
uniprot id: G2RBG7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

578455:THITE 163156
gene id: 578455:THITE_163156
uniprot id: G2RAN8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

578455:THITE 2107713
gene id: 578455:THITE_2107713
uniprot id: G2QUR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2120304
gene id: 578455:THITE_2120304
uniprot id: G2RA49
names: Similarity
messages: Belongs to the FMO family.

578455:THITE 2122749
gene id: 578455:THITE_2122749
uniprot id: G2RE68
names: Subcellular Location Annotation
messages: Cell membrane

578455:THITE 2118718
gene id: 578455:THITE_2118718
uniprot id: G2RAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

578455:THITE 2115146
gene id: 578455:THITE_2115146
uniprot id: G2R3F7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 38252
gene id: 578455:THITE_38252
uniprot id: G2R470
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2115141
gene id: 578455:THITE_2115141
uniprot id: G2R3F4
names: Similarity
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.

578455:THITE 2118722
gene id: 578455:THITE_2118722
uniprot id: G2RAN4
names: Similarity
messages: Belongs to the peptidase M24 family.

578455:THITE 2107682
gene id: 578455:THITE_2107682
uniprot id: G2QUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

578455:THITE 2111102
gene id: 578455:THITE_2111102
uniprot id: G2QWJ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2111078
gene id: 578455:THITE_2111078
uniprot id: G2QWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

578455:THITE 2116843
gene id: 578455:THITE_2116843
uniprot id: G2R775
names: Function
names: Similarity
messages: Belongs to the RTC5 family.
messages: May be involved in a process influencing telomere capping.

578455:THITE 2130975
gene id: 578455:THITE_2130975
uniprot id: G2RC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

578455:THITE 2121011
gene id: 578455:THITE_2121011
uniprot id: G2RE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

578455:THITE 112373
gene id: 578455:THITE_112373
uniprot id: G2QRY4
names: Similarity
messages: Belongs to the acetyltransferase family. GCN5 subfamily.

578455:THITE 2112132
gene id: 578455:THITE_2112132
uniprot id: G2R504
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117532
gene id: 578455:THITE_2117532
uniprot id: G2R873
names: Similarity
messages: Belongs to the tannase family.

578455:THITE 2106721
gene id: 578455:THITE_2106721
uniprot id: G2QRF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2110535
gene id: 578455:THITE_2110535
uniprot id: G2QT79
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114319
gene id: 578455:THITE_2114319
uniprot id: G2QZ70
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

578455:THITE 2169616
gene id: 578455:THITE_2169616
uniprot id: G2QQY4
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

578455:THITE 2116066
gene id: 578455:THITE_2116066
uniprot id: G2QZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 2079890
gene id: 578455:THITE_2079890
uniprot id: G2RAY1
names: Function
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).

578455:THITE 2113412
gene id: 578455:THITE_2113412
uniprot id: G2R2U9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2013434
gene id: 578455:THITE_2013434
uniprot id: G2R977
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

578455:THITE 2116306
gene id: 578455:THITE_2116306
uniprot id: G2R8K9
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

578455:THITE 133152
gene id: 578455:THITE_133152
uniprot id: G2R1G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Belongs to the NAC-alpha family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2114239
gene id: 578455:THITE_2114239
uniprot id: G2QYS5
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

578455:THITE 2111729
gene id: 578455:THITE_2111729
uniprot id: G2R393
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

578455:THITE 2119055
gene id: 578455:THITE_2119055
uniprot id: G2RB81
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2115066
gene id: 578455:THITE_2115066
uniprot id: G2R308
names: Similarity
messages: Belongs to the CAP family.

578455:THITE 2063064
gene id: 578455:THITE_2063064
uniprot id: G2QTG5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.

578455:THITE 2121743
gene id: 578455:THITE_2121743
uniprot id: G2RF90
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

578455:THITE 2113640
gene id: 578455:THITE_2113640
uniprot id: G2R3R5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

578455:THITE 122396
gene id: 578455:THITE_122396
uniprot id: G2RE94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Chromosome
messages: Component of the NuA4 histone acetyltransferase complex.

578455:THITE 2080139
gene id: 578455:THITE_2080139
uniprot id: G2RBK1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 32934
gene id: 578455:THITE_32934
uniprot id: G2R1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Late endosome membrane

578455:THITE 2122715
gene id: 578455:THITE_2122715
uniprot id: G2RDZ6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113096
gene id: 578455:THITE_2113096
uniprot id: G2R1K7
names: Caution
names: Similarity
messages: Belongs to the acetokinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2116771
gene id: 578455:THITE_2116771
uniprot id: G2R730
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

578455:THITE 2121787
gene id: 578455:THITE_2121787
uniprot id: G2RFA9
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

578455:THITE 2040898
gene id: 578455:THITE_2040898
uniprot id: G2QSC0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2153916
gene id: 578455:THITE_2153916
uniprot id: G2R434
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2119993
gene id: 578455:THITE_2119993
uniprot id: G2R9B3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2032205
gene id: 578455:THITE_2032205
uniprot id: G2R3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

578455:THITE 2112387
gene id: 578455:THITE_2112387
uniprot id: G2QYM8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124189
gene id: 578455:THITE_2124189
uniprot id: G2RIE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

578455:THITE 2115007
gene id: 578455:THITE_2115007
uniprot id: G2R2M4
names: Similarity
messages: Belongs to the SUN family.

578455:THITE 2049272
gene id: 578455:THITE_2049272
uniprot id: G2R1E5
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2121028
gene id: 578455:THITE_2121028
uniprot id: G2REB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

578455:THITE 2116317
gene id: 578455:THITE_2116317
uniprot id: G2R8M1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 123205
gene id: 578455:THITE_123205
uniprot id: G2RD75
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2120651
gene id: 578455:THITE_2120651
uniprot id: G2RD53
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2110762
gene id: 578455:THITE_2110762
uniprot id: G2QUH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

578455:THITE 2106367
gene id: 578455:THITE_2106367
uniprot id: G2QX95
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

578455:THITE 2113524
gene id: 578455:THITE_2113524
uniprot id: G2R3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

578455:THITE 2115928
gene id: 578455:THITE_2115928
uniprot id: G2QYX4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114832
gene id: 578455:THITE_2114832
uniprot id: G2R235
names: Similarity
messages: Belongs to the SF3A2 family.

578455:THITE 2123173
gene id: 578455:THITE_2123173
uniprot id: G2RGY4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2117595
gene id: 578455:THITE_2117595
uniprot id: G2R8B6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 157851
gene id: 578455:THITE_157851
uniprot id: G2QWX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2116567
gene id: 578455:THITE_2116567
uniprot id: G2R6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 2110027
gene id: 578455:THITE_2110027
uniprot id: G2QRB2
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

578455:THITE 2115636
gene id: 578455:THITE_2115636
uniprot id: G2R5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

578455:THITE 152693
gene id: 578455:THITE_152693
uniprot id: G2R2D7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

578455:THITE 2050521
gene id: 578455:THITE_2050521
uniprot id: G2R6C4
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2056274
gene id: 578455:THITE_2056274
uniprot id: G2RD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2108132
gene id: 578455:THITE_2108132
uniprot id: G2QXU2
names: Function
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 2115422
gene id: 578455:THITE_2115422
uniprot id: G2R4E8
names: Similarity
messages: Belongs to the wetA family.

578455:THITE 134121
gene id: 578455:THITE_134121
uniprot id: G2QRL2
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

578455:THITE 2115021
gene id: 578455:THITE_2115021
uniprot id: G2R2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 75063
gene id: 578455:THITE_75063
uniprot id: G2RGZ9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113702
gene id: 578455:THITE_2113702
uniprot id: G2R3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

578455:THITE 43241
gene id: 578455:THITE_43241
uniprot id: G2RAQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2111388
gene id: 578455:THITE_2111388
uniprot id: G2R2A2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2084907
gene id: 578455:THITE_2084907
uniprot id: G2QRP2
names: Similarity
messages: Belongs to the CoA-transferase III family.

578455:THITE 2109854
gene id: 578455:THITE_2109854
uniprot id: G2QY22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

578455:THITE 2113222
gene id: 578455:THITE_2113222
uniprot id: G2R210
names: Similarity
messages: Belongs to the phosphohexose mutase family.

578455:THITE 2171547
gene id: 578455:THITE_2171547
uniprot id: G2RHF2
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

578455:THITE 2063410
gene id: 578455:THITE_2063410
uniprot id: G2QXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

578455:THITE 2117755
gene id: 578455:THITE_2117755
uniprot id: G2R8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

578455:THITE 2120904
gene id: 578455:THITE_2120904
uniprot id: G2RE21
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 124350
gene id: 578455:THITE_124350
uniprot id: G2RHP7
names: Function
names: Similarity
messages: Belongs to the exportin family.
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.

578455:THITE 2117218
gene id: 578455:THITE_2117218
uniprot id: G2R7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

578455:THITE 121184
gene id: 578455:THITE_121184
uniprot id: G2QS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

578455:THITE 2120709
gene id: 578455:THITE_2120709
uniprot id: G2RDG5
names: Similarity
messages: Belongs to the PHAF1 family.

578455:THITE 45191
gene id: 578455:THITE_45191
uniprot id: G2RFA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

578455:THITE 2112341
gene id: 578455:THITE_2112341
uniprot id: G2QYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane
messages: Peroxisome membrane

578455:THITE 2110607
gene id: 578455:THITE_2110607
uniprot id: G2QTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 35750
gene id: 578455:THITE_35750
uniprot id: G2QZF0
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

578455:THITE 2115418
gene id: 578455:THITE_2115418
uniprot id: G2R4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

578455:THITE 2122496
gene id: 578455:THITE_2122496
uniprot id: G2RDC3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115772
gene id: 578455:THITE_2115772
uniprot id: G2QYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

578455:THITE 2040192
gene id: 578455:THITE_2040192
uniprot id: G2QX50
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2106902
gene id: 578455:THITE_2106902
uniprot id: G2QRZ0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

578455:THITE 2116588
gene id: 578455:THITE_2116588
uniprot id: G2R6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.

578455:THITE 2124504
gene id: 578455:THITE_2124504
uniprot id: G2RFW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

578455:THITE 129386
gene id: 578455:THITE_129386
uniprot id: G2R1C0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

578455:THITE 128638
gene id: 578455:THITE_128638
uniprot id: G2R0M0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

578455:THITE 160751
gene id: 578455:THITE_160751
uniprot id: G2R6C6
names: Similarity
messages: Belongs to the CDIP1/LITAF family.

578455:THITE 2120924
gene id: 578455:THITE_2120924
uniprot id: G2RE27
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

578455:THITE 125400
gene id: 578455:THITE_125400
uniprot id: G2R7A5
names: Similarity
messages: Belongs to the cytochrome b5 family.

578455:THITE 2108335
gene id: 578455:THITE_2108335
uniprot id: G2QR41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2108012
gene id: 578455:THITE_2108012
uniprot id: G2QWV6
names: Similarity
messages: Belongs to the AAA ATPase family.

578455:THITE 131637
gene id: 578455:THITE_131637
uniprot id: G2RH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

578455:THITE 2113061
gene id: 578455:THITE_2113061
uniprot id: G2R1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

578455:THITE 2123700
gene id: 578455:THITE_2123700
uniprot id: G2RHT3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

578455:THITE 48562
gene id: 578455:THITE_48562
uniprot id: G2QSQ0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

578455:THITE 2119058
gene id: 578455:THITE_2119058
uniprot id: G2RB91
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 152112
gene id: 578455:THITE_152112
uniprot id: G2QZR0
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2114943
gene id: 578455:THITE_2114943
uniprot id: G2R2J5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

578455:THITE 2123645
gene id: 578455:THITE_2123645
uniprot id: G2RHR1
names: Similarity
messages: Belongs to the PITHD1 family.

578455:THITE 2114383
gene id: 578455:THITE_2114383
uniprot id: G2QZL6
names: Similarity
messages: Belongs to the XPC family.

578455:THITE 2118585
gene id: 578455:THITE_2118585
uniprot id: G2RAC4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2041884
gene id: 578455:THITE_2041884
uniprot id: G2QWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 54 family.
messages: Secreted

578455:THITE 2113658
gene id: 578455:THITE_2113658
uniprot id: G2R3S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

578455:THITE 2119421
gene id: 578455:THITE_2119421
uniprot id: G2RBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

578455:THITE 2119254
gene id: 578455:THITE_2119254
uniprot id: G2RBJ0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117577
gene id: 578455:THITE_2117577
uniprot id: G2R8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

578455:THITE 2085345
gene id: 578455:THITE_2085345
uniprot id: G2QVQ1
names: Similarity
messages: Belongs to the tpcK family.

578455:THITE 2149383
gene id: 578455:THITE_2149383
uniprot id: G2QRR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

578455:THITE 2115026
gene id: 578455:THITE_2115026
uniprot id: G2R2N3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2114524
gene id: 578455:THITE_2114524
uniprot id: G2R052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2106230
gene id: 578455:THITE_2106230
uniprot id: G2QWP7
names: Similarity
messages: Belongs to the PP2C family.

578455:THITE 2113306
gene id: 578455:THITE_2113306
uniprot id: G2R2E8
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

578455:THITE 2115678
gene id: 578455:THITE_2115678
uniprot id: G2R5C6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).
messages: Mitochondrion

578455:THITE 43951
gene id: 578455:THITE_43951
uniprot id: G2RBI2
names: Function
names: Similarity
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.

578455:THITE 2107735
gene id: 578455:THITE_2107735
uniprot id: G2QV35
names: Similarity
messages: Belongs to the HMBS family.

578455:THITE 2071900
gene id: 578455:THITE_2071900
uniprot id: G2RGA8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

578455:THITE 2090493
gene id: 578455:THITE_2090493
uniprot id: G2RB10
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107061
gene id: 578455:THITE_2107061
uniprot id: G2QSG2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

578455:THITE 35106
gene id: 578455:THITE_35106
uniprot id: G2QZU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

578455:THITE 37681
gene id: 578455:THITE_37681
uniprot id: G2R3Q8
names: Similarity
messages: Belongs to the PDCD5 family.

578455:THITE 2112983
gene id: 578455:THITE_2112983
uniprot id: G2R1H1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

578455:THITE 2025911
gene id: 578455:THITE_2025911
uniprot id: G2R3Y5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

578455:THITE 2119818
gene id: 578455:THITE_2119818
uniprot id: G2R8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

578455:THITE 2118328
gene id: 578455:THITE_2118328
uniprot id: G2R9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2115893
gene id: 578455:THITE_2115893
uniprot id: G2QYV9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

578455:THITE 2109026
gene id: 578455:THITE_2109026
uniprot id: G2QTF4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 2111906
gene id: 578455:THITE_2111906
uniprot id: G2R431
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

578455:THITE 2122945
gene id: 578455:THITE_2122945
uniprot id: G2RGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

578455:THITE 2106681
gene id: 578455:THITE_2106681
uniprot id: G2QR24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

578455:THITE 2122245
gene id: 578455:THITE_2122245
uniprot id: G2RCH9
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

578455:THITE 2170662
gene id: 578455:THITE_2170662
uniprot id: G2R7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2120626
gene id: 578455:THITE_2120626
uniprot id: G2RCY1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 133921
gene id: 578455:THITE_133921
uniprot id: G2QUM8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

578455:THITE 2123506
gene id: 578455:THITE_2123506
uniprot id: G2RHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Nucleus

578455:THITE 2170501
gene id: 578455:THITE_2170501
uniprot id: G2QZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

578455:THITE 2124629
gene id: 578455:THITE_2124629
uniprot id: G2RG33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

578455:THITE 2118870
gene id: 578455:THITE_2118870
uniprot id: G2RAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

578455:THITE 2142725
gene id: 578455:THITE_2142725
uniprot id: G2R283
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2150567
gene id: 578455:THITE_2150567
uniprot id: G2R5B7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

578455:THITE 110245
gene id: 578455:THITE_110245
uniprot id: G2R4G8
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 2120540
gene id: 578455:THITE_2120540
uniprot id: G2RCL0
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

578455:THITE 2122201
gene id: 578455:THITE_2122201
uniprot id: G2RCD7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 2106724
gene id: 578455:THITE_2106724
uniprot id: G2QRF6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112849
gene id: 578455:THITE_2112849
uniprot id: G2R0W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

578455:THITE 2118293
gene id: 578455:THITE_2118293
uniprot id: G2R9M6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

578455:THITE 2114922
gene id: 578455:THITE_2114922
uniprot id: G2R2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

578455:THITE 2113283
gene id: 578455:THITE_2113283
uniprot id: G2R2E0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

578455:THITE 2122416
gene id: 578455:THITE_2122416
uniprot id: G2RD24
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

578455:THITE 2115779
gene id: 578455:THITE_2115779
uniprot id: G2QYE4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

578455:THITE 2051273
gene id: 578455:THITE_2051273
uniprot id: G2R7V3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2043428
gene id: 578455:THITE_2043428
uniprot id: G2R1W0
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

578455:THITE 35553
gene id: 578455:THITE_35553
uniprot id: G2R3E1
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2116913
gene id: 578455:THITE_2116913
uniprot id: G2R7A4
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2119908
gene id: 578455:THITE_2119908
uniprot id: G2R970
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

578455:THITE 2121237
gene id: 578455:THITE_2121237
uniprot id: G2REP4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 2107590
gene id: 578455:THITE_2107590
uniprot id: G2QUA9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

578455:THITE 2123502
gene id: 578455:THITE_2123502
uniprot id: G2RHJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2124366
gene id: 578455:THITE_2124366
uniprot id: G2RFR7
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

578455:THITE 2115304
gene id: 578455:THITE_2115304
uniprot id: G2R3Y4
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

578455:THITE 2117189
gene id: 578455:THITE_2117189
uniprot id: G2R7Q8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2119039
gene id: 578455:THITE_2119039
uniprot id: G2RB71
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

578455:THITE 2026979
gene id: 578455:THITE_2026979
uniprot id: G2R939
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

578455:THITE 2073368
gene id: 578455:THITE_2073368
uniprot id: G2QRJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: spindle

578455:THITE 2112699
gene id: 578455:THITE_2112699
uniprot id: G2R007
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

578455:THITE 2065666
gene id: 578455:THITE_2065666
uniprot id: G2R2I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

578455:THITE 2144764
gene id: 578455:THITE_2144764
uniprot id: G2R186
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2111793
gene id: 578455:THITE_2111793
uniprot id: G2R3M3
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

578455:THITE 2115989
gene id: 578455:THITE_2115989
uniprot id: G2QZD1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 36647
gene id: 578455:THITE_36647
uniprot id: G2R215
names: Similarity
messages: Belongs to the helicase family.

578455:THITE 2124003
gene id: 578455:THITE_2124003
uniprot id: G2RI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

578455:THITE 13894
gene id: 578455:THITE_13894
uniprot id: G2RGA2
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 135612
gene id: 578455:THITE_135612
uniprot id: G2QSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Chromosome

578455:THITE 2051060
gene id: 578455:THITE_2051060
uniprot id: G2R7Q9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122733
gene id: 578455:THITE_2122733
uniprot id: G2RE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

578455:THITE 2107866
gene id: 578455:THITE_2107866
uniprot id: G2QVN5
names: Similarity
messages: Belongs to the SGT1 family.

578455:THITE 2115624
gene id: 578455:THITE_2115624
uniprot id: G2R5A4
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2128764
gene id: 578455:THITE_2128764
uniprot id: G2R340
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.

578455:THITE 2106307
gene id: 578455:THITE_2106307
uniprot id: G2QX69
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

578455:THITE 2110636
gene id: 578455:THITE_2110636
uniprot id: G2QU10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2109794
gene id: 578455:THITE_2109794
uniprot id: G2QXZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

578455:THITE 2117402
gene id: 578455:THITE_2117402
uniprot id: G2R807
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THI4 family.
messages: Binds 1 Fe cation per subunit.
messages: Cytoplasm
messages: During the catalytic reaction, a sulfide is transferred from Cys-222 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
messages: Nucleus

578455:THITE 125507
gene id: 578455:THITE_125507
uniprot id: G2R6Q9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

578455:THITE 2120995
gene id: 578455:THITE_2120995
uniprot id: G2RE51
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

578455:THITE 2109117
gene id: 578455:THITE_2109117
uniprot id: G2QTJ4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

578455:THITE 163407
gene id: 578455:THITE_163407
uniprot id: G2R8X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

578455:THITE 2108151
gene id: 578455:THITE_2108151
uniprot id: G2QXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

578455:THITE 2119959
gene id: 578455:THITE_2119959
uniprot id: G2R990
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2115082
gene id: 578455:THITE_2115082
uniprot id: G2R316
names: Similarity
messages: Belongs to the FAH family.

578455:THITE 2171583
gene id: 578455:THITE_2171583
uniprot id: G2RHT4
names: Similarity
messages: Belongs to the TTC36 family.

578455:THITE 2064808
gene id: 578455:THITE_2064808
uniprot id: G2R466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

578455:THITE 2119483
gene id: 578455:THITE_2119483
uniprot id: G2RBV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2106351
gene id: 578455:THITE_2106351
uniprot id: G2QX89
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121001
gene id: 578455:THITE_2121001
uniprot id: G2RE54
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2126411
gene id: 578455:THITE_2126411
uniprot id: G2QXH2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

578455:THITE 2122740
gene id: 578455:THITE_2122740
uniprot id: G2RE65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

578455:THITE 48974
gene id: 578455:THITE_48974
uniprot id: G2QW04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

578455:THITE 2120628
gene id: 578455:THITE_2120628
uniprot id: G2RCY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

578455:THITE 2118290
gene id: 578455:THITE_2118290
uniprot id: G2R9M5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113137
gene id: 578455:THITE_2113137
uniprot id: G2R1X6
names: Similarity
messages: Belongs to the cyclin family.

578455:THITE 2120800
gene id: 578455:THITE_2120800
uniprot id: G2RDR9
names: Similarity
messages: Belongs to the PPP4R2 family.

578455:THITE 2121235
gene id: 578455:THITE_2121235
uniprot id: G2REP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2123602
gene id: 578455:THITE_2123602
uniprot id: G2RHP4
names: Similarity
messages: Belongs to the VPS29 family.

578455:THITE 121780
gene id: 578455:THITE_121780
uniprot id: G2RBA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

578455:THITE 129804
gene id: 578455:THITE_129804
uniprot id: G2QWU2
names: Similarity
messages: Belongs to the DCP1 family.
messages: Belongs to the SWI5/SAE3 family.

578455:THITE 67476
gene id: 578455:THITE_67476
uniprot id: G2R3V1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113908
gene id: 578455:THITE_2113908
uniprot id: G2R4P5
names: Similarity
messages: Belongs to the UPF0507 family.

578455:THITE 2076497
gene id: 578455:THITE_2076497
uniprot id: G2R503
names: Similarity
messages: Belongs to the SCO1/2 family.

578455:THITE 2121849
gene id: 578455:THITE_2121849
uniprot id: G2RFD6
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

578455:THITE 2036222
gene id: 578455:THITE_2036222
uniprot id: G2RCQ7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121278
gene id: 578455:THITE_2121278
uniprot id: G2RER2
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

578455:THITE 2116031
gene id: 578455:THITE_2116031
uniprot id: G2QZR8
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

578455:THITE 2118950
gene id: 578455:THITE_2118950
uniprot id: G2RB38
names: Similarity
messages: Belongs to the TIP41 family.

578455:THITE 2107700
gene id: 578455:THITE_2107700
uniprot id: G2QUQ8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 2110170
gene id: 578455:THITE_2110170
uniprot id: G2QRU1
names: Similarity
messages: Belongs to the CNOT9 family.

578455:THITE 2110581
gene id: 578455:THITE_2110581
uniprot id: G2QTL4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

578455:THITE 122851
gene id: 578455:THITE_122851
uniprot id: G2RF37
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2115820
gene id: 578455:THITE_2115820
uniprot id: G2QYG2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107381
gene id: 578455:THITE_2107381
uniprot id: G2QTS6
names: Similarity
messages: Belongs to the IF-3 family.

578455:THITE 2142055
gene id: 578455:THITE_2142055
uniprot id: G2QQU0
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

578455:THITE 2119849
gene id: 578455:THITE_2119849
uniprot id: G2R8Z0
names: Similarity
messages: Belongs to the AAA ATPase family.

578455:THITE 2124014
gene id: 578455:THITE_2124014
uniprot id: G2RI65
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

578455:THITE 56460
gene id: 578455:THITE_56460
uniprot id: G2QY68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

578455:THITE 2123595
gene id: 578455:THITE_2123595
uniprot id: G2RHP0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2072333
gene id: 578455:THITE_2072333
uniprot id: G2QQT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

578455:THITE 2120993
gene id: 578455:THITE_2120993
uniprot id: G2RE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

578455:THITE 2050087
gene id: 578455:THITE_2050087
uniprot id: G2R8S3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2071939
gene id: 578455:THITE_2071939
uniprot id: G2RGJ3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

578455:THITE 131896
gene id: 578455:THITE_131896
uniprot id: G2RFV7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

578455:THITE 65995
gene id: 578455:THITE_65995
uniprot id: G2R0R7
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

578455:THITE 2145591
gene id: 578455:THITE_2145591
uniprot id: G2R6A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2117599
gene id: 578455:THITE_2117599
uniprot id: G2R8B8
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

578455:THITE 2109424
gene id: 578455:THITE_2109424
uniprot id: G2QVP9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

578455:THITE 2064289
gene id: 578455:THITE_2064289
uniprot id: G2QZB6
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2119569
gene id: 578455:THITE_2119569
uniprot id: G2RBY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.

578455:THITE 2060243
gene id: 578455:THITE_2060243
uniprot id: G2RFS0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2155788
gene id: 578455:THITE_2155788
uniprot id: G2R982
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

578455:THITE 2115028
gene id: 578455:THITE_2115028
uniprot id: G2R2N4
names: Similarity
messages: Belongs to the IST1 family.

578455:THITE 2109547
gene id: 578455:THITE_2109547
uniprot id: G2QWF9
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2108499
gene id: 578455:THITE_2108499
uniprot id: G2QRL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

578455:THITE 2109652
gene id: 578455:THITE_2109652
uniprot id: G2QXH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

578455:THITE 2111872
gene id: 578455:THITE_2111872
uniprot id: G2R3Q2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2058539
gene id: 578455:THITE_2058539
uniprot id: G2RGB5
names: Similarity
messages: Belongs to the polysaccharide monooxygenase AA13 family.

578455:THITE 2117276
gene id: 578455:THITE_2117276
uniprot id: G2R7U3
names: Similarity
messages: Belongs to the COG3 family.

578455:THITE 2117904
gene id: 578455:THITE_2117904
uniprot id: G2R669
names: Similarity
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.

578455:THITE 2081505
gene id: 578455:THITE_2081505
uniprot id: G2REU2
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

578455:THITE 2110945
gene id: 578455:THITE_2110945
uniprot id: G2QVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

578455:THITE 2114500
gene id: 578455:THITE_2114500
uniprot id: G2R039
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

578455:THITE 2060019
gene id: 578455:THITE_2060019
uniprot id: G2RGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

578455:THITE 2121114
gene id: 578455:THITE_2121114
uniprot id: G2REF6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2114673
gene id: 578455:THITE_2114673
uniprot id: G2R136
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2108955
gene id: 578455:THITE_2108955
uniprot id: G2QT17
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 43883
gene id: 578455:THITE_43883
uniprot id: G2R9B2
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

578455:THITE 162931
gene id: 578455:THITE_162931
uniprot id: G2QT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

578455:THITE 2121525
gene id: 578455:THITE_2121525
uniprot id: G2RF11
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

578455:THITE 2123367
gene id: 578455:THITE_2123367
uniprot id: G2RH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

578455:THITE 2107164
gene id: 578455:THITE_2107164
uniprot id: G2QSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.

578455:THITE 2054959
gene id: 578455:THITE_2054959
uniprot id: G2RBM1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 124165
gene id: 578455:THITE_124165
uniprot id: G2RGS2
names: Similarity
messages: Belongs to the PP2C family.

578455:THITE 2123513
gene id: 578455:THITE_2123513
uniprot id: G2RHJ7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2119447
gene id: 578455:THITE_2119447
uniprot id: G2RBT7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

578455:THITE 2119927
gene id: 578455:THITE_2119927
uniprot id: G2R975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

578455:THITE 2115545
gene id: 578455:THITE_2115545
uniprot id: G2R4W2
names: Similarity
messages: Belongs to the group II decarboxylase family.

578455:THITE 2072080
gene id: 578455:THITE_2072080
uniprot id: G2QW48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

578455:THITE 2123027
gene id: 578455:THITE_2123027
uniprot id: G2RGM3
names: Similarity
messages: Belongs to the Mo25 family.

578455:THITE 2108140
gene id: 578455:THITE_2108140
uniprot id: G2QXU8
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

578455:THITE 2113980
gene id: 578455:THITE_2113980
uniprot id: G2R4T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

578455:THITE 135405
gene id: 578455:THITE_135405
uniprot id: G2QUX0
names: Similarity
messages: Belongs to the OBAP family.

578455:THITE 2032283
gene id: 578455:THITE_2032283
uniprot id: G2RGV5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108853
gene id: 578455:THITE_2108853
uniprot id: G2QSL5
names: Similarity
messages: Belongs to the WD repeat LST8 family.

578455:THITE 2108904
gene id: 578455:THITE_2108904
uniprot id: G2QSZ8
names: Similarity
messages: Belongs to the cytidylyltransferase family.

578455:THITE 2120943
gene id: 578455:THITE_2120943
uniprot id: G2RE34
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112540
gene id: 578455:THITE_2112540
uniprot id: G2QZG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2010413
gene id: 578455:THITE_2010413
uniprot id: G2QS76
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2116166
gene id: 578455:THITE_2116166
uniprot id: G2R092
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

578455:THITE 70352
gene id: 578455:THITE_70352
uniprot id: G2QR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

578455:THITE 2116456
gene id: 578455:THITE_2116456
uniprot id: G2R623
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

578455:THITE 65959
gene id: 578455:THITE_65959
uniprot id: G2R193
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117426
gene id: 578455:THITE_2117426
uniprot id: G2R817
names: Similarity
messages: Belongs to the OSBP family.

578455:THITE 2154984
gene id: 578455:THITE_2154984
uniprot id: G2R6N7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

578455:THITE 2110682
gene id: 578455:THITE_2110682
uniprot id: G2QU37
names: Similarity
messages: Belongs to the rtf2 family.

578455:THITE 2116279
gene id: 578455:THITE_2116279
uniprot id: G2R179
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2120840
gene id: 578455:THITE_2120840
uniprot id: G2RDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

578455:THITE 77005
gene id: 578455:THITE_77005
uniprot id: G2R6Q8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2120242
gene id: 578455:THITE_2120242
uniprot id: G2R9V8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2110457
gene id: 578455:THITE_2110457
uniprot id: G2QT39
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

578455:THITE 2110373
gene id: 578455:THITE_2110373
uniprot id: G2QSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

578455:THITE 2090184
gene id: 578455:THITE_2090184
uniprot id: G2R9C7
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family.
messages: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.

578455:THITE 2116216
gene id: 578455:THITE_2116216
uniprot id: G2R0R8
names: Function
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS.

578455:THITE 2016423
gene id: 578455:THITE_2016423
uniprot id: G2QZL0
names: Similarity
messages: Belongs to the MAD2 family.

578455:THITE 2117584
gene id: 578455:THITE_2117584
uniprot id: G2R8A7
names: Similarity
messages: Belongs to the tannase family.

578455:THITE 2124858
gene id: 578455:THITE_2124858
uniprot id: G2RH34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane
messages: Vacuole membrane

578455:THITE 2119126
gene id: 578455:THITE_2119126
uniprot id: G2RBD2
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

578455:THITE 2108542
gene id: 578455:THITE_2108542
uniprot id: G2QRN4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

578455:THITE 2109658
gene id: 578455:THITE_2109658
uniprot id: G2QXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

578455:THITE 2106112
gene id: 578455:THITE_2106112
uniprot id: G2QW30
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

578455:THITE 2121824
gene id: 578455:THITE_2121824
uniprot id: G2RFC7
names: Similarity
messages: Belongs to the calreticulin family.

578455:THITE 14793
gene id: 578455:THITE_14793
uniprot id: G2R5K8
names: Similarity
messages: Belongs to the UPF0696 family.

578455:THITE 2081127
gene id: 578455:THITE_2081127
uniprot id: G2RDH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2109753
gene id: 578455:THITE_2109753
uniprot id: G2QXX5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

578455:THITE 2142595
gene id: 578455:THITE_2142595
uniprot id: G2QX23
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123383
gene id: 578455:THITE_2123383
uniprot id: G2RHA1
names: Similarity
messages: Belongs to the SEC6 family.

578455:THITE 2116008
gene id: 578455:THITE_2116008
uniprot id: G2QZE7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112572
gene id: 578455:THITE_2112572
uniprot id: G2QZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

578455:THITE 2141300
gene id: 578455:THITE_2141300
uniprot id: G2QXC7
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2115931
gene id: 578455:THITE_2115931
uniprot id: G2QYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2123276
gene id: 578455:THITE_2123276
uniprot id: G2RH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: Required for pre-18S rRNA processing. May bind microtubules.
messages: nucleolus

578455:THITE 2171067
gene id: 578455:THITE_2171067
uniprot id: G2R9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

578455:THITE 132601
gene id: 578455:THITE_132601
uniprot id: G2R412
names: Similarity
messages: Belongs to the CCDC124 family.

578455:THITE 165162
gene id: 578455:THITE_165162
uniprot id: G2R6I5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2044936
gene id: 578455:THITE_2044936
uniprot id: G2R0T0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2154358
gene id: 578455:THITE_2154358
uniprot id: G2R488
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: Component of the eIF4F complex, which composition varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G.

578455:THITE 2122825
gene id: 578455:THITE_2122825
uniprot id: G2REA1
names: Similarity
messages: Belongs to the uridine kinase family.

578455:THITE 2124338
gene id: 578455:THITE_2124338
uniprot id: G2RFQ4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

578455:THITE 2119499
gene id: 578455:THITE_2119499
uniprot id: G2RBW5
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

578455:THITE 2069256
gene id: 578455:THITE_2069256
uniprot id: G2RAI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

578455:THITE 2123226
gene id: 578455:THITE_2123226
uniprot id: G2RH07
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2124540
gene id: 578455:THITE_2124540
uniprot id: G2RFY4
names: Similarity
messages: Belongs to the RCAN family.

578455:THITE 132141
gene id: 578455:THITE_132141
uniprot id: G2R840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

578455:THITE 2121210
gene id: 578455:THITE_2121210
uniprot id: G2REN1
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

578455:THITE 2077668
gene id: 578455:THITE_2077668
uniprot id: G2R552
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

578455:THITE 2144836
gene id: 578455:THITE_2144836
uniprot id: G2R5J7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2049345
gene id: 578455:THITE_2049345
uniprot id: G2R243
names: Similarity
messages: Belongs to the LacAB/RpiB family.

578455:THITE 2120720
gene id: 578455:THITE_2120720
uniprot id: G2RDH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

578455:THITE 110377
gene id: 578455:THITE_110377
uniprot id: G2R341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2050159
gene id: 578455:THITE_2050159
uniprot id: G2R5K0
names: Similarity
messages: Belongs to the XFP family.

578455:THITE 107262
gene id: 578455:THITE_107262
uniprot id: G2R2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

578455:THITE 2057638
gene id: 578455:THITE_2057638
uniprot id: G2RF74
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2113636
gene id: 578455:THITE_2113636
uniprot id: G2R3R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

578455:THITE 2050929
gene id: 578455:THITE_2050929
uniprot id: G2R7W9
names: Similarity
messages: Belongs to the argonaute family.

578455:THITE 2155389
gene id: 578455:THITE_2155389
uniprot id: G2R9G3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 39903
gene id: 578455:THITE_39903
uniprot id: G2QSV4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

578455:THITE 2118308
gene id: 578455:THITE_2118308
uniprot id: G2R9N2
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

578455:THITE 2111611
gene id: 578455:THITE_2111611
uniprot id: G2R347
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

578455:THITE 2114881
gene id: 578455:THITE_2114881
uniprot id: G2R268
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

578455:THITE 2107478
gene id: 578455:THITE_2107478
uniprot id: G2QU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

578455:THITE 2082061
gene id: 578455:THITE_2082061
uniprot id: G2RCP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2121201
gene id: 578455:THITE_2121201
uniprot id: G2REM9
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2122080
gene id: 578455:THITE_2122080
uniprot id: G2RFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: nucleolus

578455:THITE 2091336
gene id: 578455:THITE_2091336
uniprot id: G2RCU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2070892
gene id: 578455:THITE_2070892
uniprot id: G2RGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2050978
gene id: 578455:THITE_2050978
uniprot id: G2R5F5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2110318
gene id: 578455:THITE_2110318
uniprot id: G2QSB6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

578455:THITE 2053903
gene id: 578455:THITE_2053903
uniprot id: G2R945
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 25004
gene id: 578455:THITE_25004
uniprot id: G2RDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

578455:THITE 2089287
gene id: 578455:THITE_2089287
uniprot id: G2R791
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

578455:THITE 66333
gene id: 578455:THITE_66333
uniprot id: G2R5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

578455:THITE 2115063
gene id: 578455:THITE_2115063
uniprot id: G2R307
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

578455:THITE 2117994
gene id: 578455:THITE_2117994
uniprot id: G2R6B6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

578455:THITE 2079792
gene id: 578455:THITE_2079792
uniprot id: G2RAM6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2171639
gene id: 578455:THITE_2171639
uniprot id: G2RI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Nucleus matrix

578455:THITE 2118204
gene id: 578455:THITE_2118204
uniprot id: G2R931
names: Similarity
messages: Belongs to the BolA/IbaG family.

578455:THITE 2114665
gene id: 578455:THITE_2114665
uniprot id: G2R126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

578455:THITE 2118583
gene id: 578455:THITE_2118583
uniprot id: G2RAC3
names: Similarity
messages: Belongs to the UPF0047 family.

578455:THITE 130699
gene id: 578455:THITE_130699
uniprot id: G2RDK4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2061664
gene id: 578455:THITE_2061664
uniprot id: G2QR23
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2156931
gene id: 578455:THITE_2156931
uniprot id: G2RGV7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114744
gene id: 578455:THITE_2114744
uniprot id: G2R1N7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2049322
gene id: 578455:THITE_2049322
uniprot id: G2R409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 109373
gene id: 578455:THITE_109373
uniprot id: G2RHE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

578455:THITE 2039864
gene id: 578455:THITE_2039864
uniprot id: G2QTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NOP16 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

578455:THITE 2156264
gene id: 578455:THITE_2156264
uniprot id: G2RFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2108104
gene id: 578455:THITE_2108104
uniprot id: G2QXS8
names: Similarity
messages: Belongs to the IlvD/Edd family.

578455:THITE 2120613
gene id: 578455:THITE_2120613
uniprot id: G2RCX3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2093464
gene id: 578455:THITE_2093464
uniprot id: G2RH31
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2108918
gene id: 578455:THITE_2108918
uniprot id: G2QT05
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

578455:THITE 2097172
gene id: 578455:THITE_2097172
uniprot id: G2RF15
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

578455:THITE 2089013
gene id: 578455:THITE_2089013
uniprot id: G2R5T6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 72528
gene id: 578455:THITE_72528
uniprot id: G2RDE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

578455:THITE 2110651
gene id: 578455:THITE_2110651
uniprot id: G2QU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

578455:THITE 2022936
gene id: 578455:THITE_2022936
uniprot id: G2R6H0
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2111582
gene id: 578455:THITE_2111582
uniprot id: G2R2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

578455:THITE 2109051
gene id: 578455:THITE_2109051
uniprot id: G2QTG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2124821
gene id: 578455:THITE_2124821
uniprot id: G2RGT9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2125792
gene id: 578455:THITE_2125792
uniprot id: G2QQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

578455:THITE 2116996
gene id: 578455:THITE_2116996
uniprot id: G2R7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2119011
gene id: 578455:THITE_2119011
uniprot id: G2RB55
names: Similarity
messages: Belongs to the RNase Z family.

578455:THITE 2062090
gene id: 578455:THITE_2062090
uniprot id: G2QTV1
names: Subcellular Location Annotation
messages: Cell membrane

578455:THITE 2122552
gene id: 578455:THITE_2122552
uniprot id: G2RDK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

578455:THITE 2106069
gene id: 578455:THITE_2106069
uniprot id: G2QW15
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2123067
gene id: 578455:THITE_2123067
uniprot id: G2RGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

578455:THITE 2116329
gene id: 578455:THITE_2116329
uniprot id: G2R5G3
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2115945
gene id: 578455:THITE_2115945
uniprot id: G2QYY4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.

578455:THITE 50748
gene id: 578455:THITE_50748
uniprot id: G2RI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

578455:THITE 155616
gene id: 578455:THITE_155616
uniprot id: G2RAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2122153
gene id: 578455:THITE_2122153
uniprot id: G2RCA8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118055
gene id: 578455:THITE_2118055
uniprot id: G2R6T8
names: Similarity
messages: Belongs to the TCP11 family.

578455:THITE 157502
gene id: 578455:THITE_157502
uniprot id: G2RDF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

578455:THITE 2109218
gene id: 578455:THITE_2109218
uniprot id: G2QUD3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

578455:THITE 2118012
gene id: 578455:THITE_2118012
uniprot id: G2R6I4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

578455:THITE 2108722
gene id: 578455:THITE_2108722
uniprot id: G2QS57
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

578455:THITE 2169937
gene id: 578455:THITE_2169937
uniprot id: G2R531
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

578455:THITE 2118925
gene id: 578455:THITE_2118925
uniprot id: G2RB28
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

578455:THITE 115398
gene id: 578455:THITE_115398
uniprot id: G2RCM6
names: Similarity
messages: Belongs to the peptidase C14B family.

578455:THITE 2119450
gene id: 578455:THITE_2119450
uniprot id: G2RBT9
names: Similarity
messages: Belongs to the peptidase C19 family.

578455:THITE 2116488
gene id: 578455:THITE_2116488
uniprot id: G2R6C9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2107603
gene id: 578455:THITE_2107603
uniprot id: G2QUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

578455:THITE 2115659
gene id: 578455:THITE_2115659
uniprot id: G2R5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

578455:THITE 2115709
gene id: 578455:THITE_2115709
uniprot id: G2R5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

578455:THITE 2108466
gene id: 578455:THITE_2108466
uniprot id: G2QRK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

578455:THITE 2111124
gene id: 578455:THITE_2111124
uniprot id: G2QWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

578455:THITE 2119053
gene id: 578455:THITE_2119053
uniprot id: G2RB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

578455:THITE 2111584
gene id: 578455:THITE_2111584
uniprot id: G2R2T3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

578455:THITE 162651
gene id: 578455:THITE_162651
uniprot id: G2QVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Secreted

578455:THITE 2040964
gene id: 578455:THITE_2040964
uniprot id: G2QSN1
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2110337
gene id: 578455:THITE_2110337
uniprot id: G2QSN2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2106386
gene id: 578455:THITE_2106386
uniprot id: G2QXA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSH4 family.
messages: Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.
messages: Endosome membrane
messages: Membrane
messages: Vacuole membrane

578455:THITE 2107150
gene id: 578455:THITE_2107150
uniprot id: G2QSW6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109446
gene id: 578455:THITE_2109446
uniprot id: G2QVR7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124845
gene id: 578455:THITE_2124845
uniprot id: G2RGW6
names: Similarity
messages: Belongs to the SDHAF4 family.

578455:THITE 2107382
gene id: 578455:THITE_2107382
uniprot id: G2QTS7
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

578455:THITE 2123471
gene id: 578455:THITE_2123471
uniprot id: G2RHF5
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

578455:THITE 2110768
gene id: 578455:THITE_2110768
uniprot id: G2QUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2119834
gene id: 578455:THITE_2119834
uniprot id: G2R8Y2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124783
gene id: 578455:THITE_2124783
uniprot id: G2RGL5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 130959
gene id: 578455:THITE_130959
uniprot id: G2REX6
names: Function
names: Similarity
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.

578455:THITE 2115417
gene id: 578455:THITE_2115417
uniprot id: G2R4E5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108037
gene id: 578455:THITE_2108037
uniprot id: G2QXB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

578455:THITE 2027381
gene id: 578455:THITE_2027381
uniprot id: G2QTR7
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

578455:THITE 2122267
gene id: 578455:THITE_2122267
uniprot id: G2RCN3
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

578455:THITE 2020879
gene id: 578455:THITE_2020879
uniprot id: G2R6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2109930
gene id: 578455:THITE_2109930
uniprot id: G2QQV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2111329
gene id: 578455:THITE_2111329
uniprot id: G2R1V4
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2021587
gene id: 578455:THITE_2021587
uniprot id: G2R094
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2108493
gene id: 578455:THITE_2108493
uniprot id: G2QRL5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

578455:THITE 35712
gene id: 578455:THITE_35712
uniprot id: G2QZN9
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2123861
gene id: 578455:THITE_2123861
uniprot id: G2RI08
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 134789
gene id: 578455:THITE_134789
uniprot id: G2RA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

578455:THITE 2123824
gene id: 578455:THITE_2123824
uniprot id: G2RHZ1
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

578455:THITE 2170736
gene id: 578455:THITE_2170736
uniprot id: G2R5P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2123329
gene id: 578455:THITE_2123329
uniprot id: G2RH72
names: Similarity
messages: Belongs to the pirin family.

578455:THITE 2089085
gene id: 578455:THITE_2089085
uniprot id: G2R657
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.

578455:THITE 126353
gene id: 578455:THITE_126353
uniprot id: G2R2S1
names: Similarity
messages: Belongs to the SUI1 family.

578455:THITE 2110595
gene id: 578455:THITE_2110595
uniprot id: G2QTM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2119958
gene id: 578455:THITE_2119958
uniprot id: G2R988
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

578455:THITE 2121041
gene id: 578455:THITE_2121041
uniprot id: G2REC2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
messages: Belongs to the MoaD family. MOCS2A subfamily.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.

578455:THITE 2037555
gene id: 578455:THITE_2037555
uniprot id: G2QVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2081909
gene id: 578455:THITE_2081909
uniprot id: G2RFK9
names: Similarity
messages: Belongs to the cyclin family.

578455:THITE 2112268
gene id: 578455:THITE_2112268
uniprot id: G2QY63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

578455:THITE 2113162
gene id: 578455:THITE_2113162
uniprot id: G2R1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

578455:THITE 2145386
gene id: 578455:THITE_2145386
uniprot id: G2R8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2118647
gene id: 578455:THITE_2118647
uniprot id: G2RAJ9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124375
gene id: 578455:THITE_2124375
uniprot id: G2RFR8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

578455:THITE 2120696
gene id: 578455:THITE_2120696
uniprot id: G2RDF6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2169375
gene id: 578455:THITE_2169375
uniprot id: G2QXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

578455:THITE 2043056
gene id: 578455:THITE_2043056
uniprot id: G2QWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.

578455:THITE 2097720
gene id: 578455:THITE_2097720
uniprot id: G2RHX5
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2106562
gene id: 578455:THITE_2106562
uniprot id: G2QQL7
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

578455:THITE 2120915
gene id: 578455:THITE_2120915
uniprot id: G2RE23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

578455:THITE 2113543
gene id: 578455:THITE_2113543
uniprot id: G2R3B2
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

578455:THITE 36621
gene id: 578455:THITE_36621
uniprot id: G2R1I6
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

578455:THITE 118353
gene id: 578455:THITE_118353
uniprot id: G2QZE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2107758
gene id: 578455:THITE_2107758
uniprot id: G2QV53
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2112000
gene id: 578455:THITE_2112000
uniprot id: G2R4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

578455:THITE 2111635
gene id: 578455:THITE_2111635
uniprot id: G2R354
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2097043
gene id: 578455:THITE_2097043
uniprot id: G2RE47
names: Similarity
messages: Belongs to the RNase PH family.

578455:THITE 2117715
gene id: 578455:THITE_2117715
uniprot id: G2R8R0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2052551
gene id: 578455:THITE_2052551
uniprot id: G2RC45
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118632
gene id: 578455:THITE_2118632
uniprot id: G2RAJ2
names: Function
names: Subcellular Location Annotation
messages: Chromosome
messages: Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.
messages: Nucleus

578455:THITE 2121469
gene id: 578455:THITE_2121469
uniprot id: G2REY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

578455:THITE 2140511
gene id: 578455:THITE_2140511
uniprot id: G2QW25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

578455:THITE 2115939
gene id: 578455:THITE_2115939
uniprot id: G2QYY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

578455:THITE 2121637
gene id: 578455:THITE_2121637
uniprot id: G2RF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

578455:THITE 2128823
gene id: 578455:THITE_2128823
uniprot id: G2R3X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

578455:THITE 2120965
gene id: 578455:THITE_2120965
uniprot id: G2RE39
names: Similarity
messages: Belongs to the OSBP family.

578455:THITE 46416
gene id: 578455:THITE_46416
uniprot id: G2REI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2171621
gene id: 578455:THITE_2171621
uniprot id: G2RI39
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2071588
gene id: 578455:THITE_2071588
uniprot id: G2RID0
names: Similarity
messages: Belongs to the Tango6 family.

578455:THITE 2111531
gene id: 578455:THITE_2111531
uniprot id: G2R2R1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124437
gene id: 578455:THITE_2124437
uniprot id: G2RFU6
names: Similarity
messages: Belongs to the nucleoporin interacting component (NIC) family.

578455:THITE 2056926
gene id: 578455:THITE_2056926
uniprot id: G2RCV5
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

578455:THITE 2120861
gene id: 578455:THITE_2120861
uniprot id: G2RDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPT35 family.
messages: Endosome membrane
messages: Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
messages: Vacuole membrane

578455:THITE 2170059
gene id: 578455:THITE_2170059
uniprot id: G2R1G0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

578455:THITE 2123314
gene id: 578455:THITE_2123314
uniprot id: G2RH66
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2062722
gene id: 578455:THITE_2062722
uniprot id: G2QRK8
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

578455:THITE 2110720
gene id: 578455:THITE_2110720
uniprot id: G2QU53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2121961
gene id: 578455:THITE_2121961
uniprot id: G2RFI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2109176
gene id: 578455:THITE_2109176
uniprot id: G2QTY4
names: Similarity
messages: Belongs to the nicotianamine synthase (NAS)-like family.

578455:THITE 2111411
gene id: 578455:THITE_2111411
uniprot id: G2R2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

578455:THITE 2109844
gene id: 578455:THITE_2109844
uniprot id: G2QY16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

578455:THITE 2108312
gene id: 578455:THITE_2108312
uniprot id: G2QQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.
messages: Membrane

578455:THITE 2039882
gene id: 578455:THITE_2039882
uniprot id: G2QW59
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2119482
gene id: 578455:THITE_2119482
uniprot id: G2RBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

578455:THITE 2062081
gene id: 578455:THITE_2062081
uniprot id: G2QTU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

578455:THITE 2113236
gene id: 578455:THITE_2113236
uniprot id: G2R214
names: Similarity
messages: Belongs to the peptidase C19 family.

578455:THITE 2154204
gene id: 578455:THITE_2154204
uniprot id: G2R1Z2
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

578455:THITE 2108507
gene id: 578455:THITE_2108507
uniprot id: G2QRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

578455:THITE 2119494
gene id: 578455:THITE_2119494
uniprot id: G2RBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

578455:THITE 2107467
gene id: 578455:THITE_2107467
uniprot id: G2QU65
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

578455:THITE 21903
gene id: 578455:THITE_21903
uniprot id: G2R4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2118956
gene id: 578455:THITE_2118956
uniprot id: G2RB40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring.
messages: Mitochondrion inner membrane

578455:THITE 2118396
gene id: 578455:THITE_2118396
uniprot id: G2R9Y7
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

578455:THITE 2106279
gene id: 578455:THITE_2106279
uniprot id: G2QX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

578455:THITE 2120068
gene id: 578455:THITE_2120068
uniprot id: G2R9I8
names: Similarity
messages: Belongs to the UPF0357 family.

578455:THITE 2110957
gene id: 578455:THITE_2110957
uniprot id: G2QVH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 45 (cellulase K) family.

578455:THITE 2107461
gene id: 578455:THITE_2107461
uniprot id: G2QU64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2112302
gene id: 578455:THITE_2112302
uniprot id: G2QYI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

578455:THITE 2113355
gene id: 578455:THITE_2113355
uniprot id: G2R2H0
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.

578455:THITE 2108228
gene id: 578455:THITE_2108228
uniprot id: G2QQN9
names: Similarity
messages: Belongs to the peptidase C12 family.

578455:THITE 2110294
gene id: 578455:THITE_2110294
uniprot id: G2QSA6
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

578455:THITE 2116565
gene id: 578455:THITE_2116565
uniprot id: G2R6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

578455:THITE 50004
gene id: 578455:THITE_50004
uniprot id: G2RH65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

578455:THITE 2107922
gene id: 578455:THITE_2107922
uniprot id: G2QW95
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

578455:THITE 2115040
gene id: 578455:THITE_2115040
uniprot id: G2R2Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

578455:THITE 2106580
gene id: 578455:THITE_2106580
uniprot id: G2QQM4
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2111312
gene id: 578455:THITE_2111312
uniprot id: G2R1U4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2120901
gene id: 578455:THITE_2120901
uniprot id: G2RE20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

578455:THITE 2096971
gene id: 578455:THITE_2096971
uniprot id: G2RDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folylpolyglutamate synthase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

578455:THITE 2107815
gene id: 578455:THITE_2107815
uniprot id: G2QVK3
names: Similarity
messages: Belongs to the RRP15 family.

578455:THITE 2119317
gene id: 578455:THITE_2119317
uniprot id: G2RBL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

578455:THITE 2115357
gene id: 578455:THITE_2115357
uniprot id: G2R417
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2152641
gene id: 578455:THITE_2152641
uniprot id: G2QWN7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2110236
gene id: 578455:THITE_2110236
uniprot id: G2QS78
names: Similarity
messages: Belongs to the IMPACT family.

578455:THITE 2043765
gene id: 578455:THITE_2043765
uniprot id: G2R115
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

578455:THITE 2041205
gene id: 578455:THITE_2041205
uniprot id: G2QV24
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2111184
gene id: 578455:THITE_2111184
uniprot id: G2R1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Membrane
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

578455:THITE 2108725
gene id: 578455:THITE_2108725
uniprot id: G2QS59
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2108707
gene id: 578455:THITE_2108707
uniprot id: G2QS50
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108379
gene id: 578455:THITE_2108379
uniprot id: G2QR57
names: Similarity
messages: Belongs to the peptidase C19 family.

578455:THITE 2124020
gene id: 578455:THITE_2124020
uniprot id: G2RI68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

578455:THITE 2123164
gene id: 578455:THITE_2123164
uniprot id: G2RGX8
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2117113
gene id: 578455:THITE_2117113
uniprot id: G2R7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

578455:THITE 2116616
gene id: 578455:THITE_2116616
uniprot id: G2R6S4
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

578455:THITE 2122927
gene id: 578455:THITE_2122927
uniprot id: G2RGC4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

578455:THITE 2122481
gene id: 578455:THITE_2122481
uniprot id: G2RDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

578455:THITE 2111529
gene id: 578455:THITE_2111529
uniprot id: G2R2R0
names: Similarity
messages: Belongs to the ELP6 family.

578455:THITE 2108292
gene id: 578455:THITE_2108292
uniprot id: G2QQR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

578455:THITE 2111737
gene id: 578455:THITE_2111737
uniprot id: G2R396
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex.
messages: Nucleus

578455:THITE 2124801
gene id: 578455:THITE_2124801
uniprot id: G2RGT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: nucleolus

578455:THITE 122652
gene id: 578455:THITE_122652
uniprot id: G2RCC4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2115047
gene id: 578455:THITE_2115047
uniprot id: G2R2Z8
names: Similarity
messages: Belongs to the AAA ATPase family.

578455:THITE 2027419
gene id: 578455:THITE_2027419
uniprot id: G2R5H4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

578455:THITE 124748
gene id: 578455:THITE_124748
uniprot id: G2RGA5
names: Function
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

578455:THITE 2114845
gene id: 578455:THITE_2114845
uniprot id: G2R247
names: Subcellular Location Annotation
messages: Chromosome

578455:THITE 2112111
gene id: 578455:THITE_2112111
uniprot id: G2R4Z4
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2122859
gene id: 578455:THITE_2122859
uniprot id: G2REH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan.
messages: Belongs to the glycosyl hydrolase 62 family.
messages: Secreted

578455:THITE 2017150
gene id: 578455:THITE_2017150
uniprot id: G2R7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

578455:THITE 2050481
gene id: 578455:THITE_2050481
uniprot id: G2R5U1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

578455:THITE 2121269
gene id: 578455:THITE_2121269
uniprot id: G2REQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

578455:THITE 2111451
gene id: 578455:THITE_2111451
uniprot id: G2R2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

578455:THITE 2116350
gene id: 578455:THITE_2116350
uniprot id: G2R5I1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

578455:THITE 2041110
gene id: 578455:THITE_2041110
uniprot id: G2QT47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2121138
gene id: 578455:THITE_2121138
uniprot id: G2REG5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

578455:THITE 2122466
gene id: 578455:THITE_2122466
uniprot id: G2RDA7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

578455:THITE 2116511
gene id: 578455:THITE_2116511
uniprot id: G2R6F1
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

578455:THITE 2119430
gene id: 578455:THITE_2119430
uniprot id: G2RBS8
names: Similarity
messages: Belongs to the PHF5 family.

578455:THITE 2056097
gene id: 578455:THITE_2056097
uniprot id: G2REP5
names: Similarity
messages: Belongs to the NPR2 family.

578455:THITE 2059663
gene id: 578455:THITE_2059663
uniprot id: G2RHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
messages: Membrane
messages: Nucleus membrane

578455:THITE 2118138
gene id: 578455:THITE_2118138
uniprot id: G2R746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2108145
gene id: 578455:THITE_2108145
uniprot id: G2QXV0
names: Similarity
messages: Belongs to the peptidase M28 family.

578455:THITE 2107732
gene id: 578455:THITE_2107732
uniprot id: G2QV34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

578455:THITE 2111691
gene id: 578455:THITE_2111691
uniprot id: G2R377
names: Similarity
messages: Belongs to the malate synthase family.

578455:THITE 2115540
gene id: 578455:THITE_2115540
uniprot id: G2R4W0
names: Similarity
messages: Belongs to the eIF-2-alpha family.

578455:THITE 2121489
gene id: 578455:THITE_2121489
uniprot id: G2REZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

578455:THITE 2113227
gene id: 578455:THITE_2113227
uniprot id: G2R211
names: Similarity
messages: Belongs to the oligoribonuclease family.

578455:THITE 59436
gene id: 578455:THITE_59436
uniprot id: G2RA27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2117329
gene id: 578455:THITE_2117329
uniprot id: G2R7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3 and histone H4.
messages: Nucleus

578455:THITE 2124286
gene id: 578455:THITE_2124286
uniprot id: G2RIG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

578455:THITE 2107877
gene id: 578455:THITE_2107877
uniprot id: G2QW56
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2108027
gene id: 578455:THITE_2108027
uniprot id: G2QWW7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116454
gene id: 578455:THITE_2116454
uniprot id: G2R622
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120110
gene id: 578455:THITE_2120110
uniprot id: G2R9K4
names: Similarity
messages: Belongs to the KTI12 family.

578455:THITE 2109039
gene id: 578455:THITE_2109039
uniprot id: G2QTG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2122479
gene id: 578455:THITE_2122479
uniprot id: G2RDB7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

578455:THITE 2123004
gene id: 578455:THITE_2123004
uniprot id: G2RGG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.

578455:THITE 2122679
gene id: 578455:THITE_2122679
uniprot id: G2RDX9
names: Similarity
messages: Belongs to the GILT family.

578455:THITE 2116474
gene id: 578455:THITE_2116474
uniprot id: G2R650
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

578455:THITE 2169226
gene id: 578455:THITE_2169226
uniprot id: G2QS08
names: Similarity
messages: Belongs to the AIM6 family.

578455:THITE 2108423
gene id: 578455:THITE_2108423
uniprot id: G2QR73
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118883
gene id: 578455:THITE_2118883
uniprot id: G2RB01
names: Similarity
messages: Belongs to the ClpA/ClpB family.

578455:THITE 75424
gene id: 578455:THITE_75424
uniprot id: G2RHX0
names: Similarity
messages: Belongs to the p23/wos2 family.

578455:THITE 2122946
gene id: 578455:THITE_2122946
uniprot id: G2RGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

578455:THITE 2109253
gene id: 578455:THITE_2109253
uniprot id: G2QUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 2122109
gene id: 578455:THITE_2122109
uniprot id: G2RC89
names: Similarity
messages: Belongs to the peptidase M16 family.

578455:THITE 2120275
gene id: 578455:THITE_2120275
uniprot id: G2R9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small Tim family.
messages: Mitochondrion inner membrane

578455:THITE 109485
gene id: 578455:THITE_109485
uniprot id: G2RIE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

578455:THITE 2118582
gene id: 578455:THITE_2118582
uniprot id: G2RAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

578455:THITE 122696
gene id: 578455:THITE_122696
uniprot id: G2RFM3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2156929
gene id: 578455:THITE_2156929
uniprot id: G2RGV4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2148271
gene id: 578455:THITE_2148271
uniprot id: G2RIH5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

578455:THITE 2169599
gene id: 578455:THITE_2169599
uniprot id: G2QY25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

578455:THITE 2110034
gene id: 578455:THITE_2110034
uniprot id: G2QRB4
names: Similarity
messages: Belongs to the CWC16 family.

578455:THITE 2114020
gene id: 578455:THITE_2114020
uniprot id: G2R560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

578455:THITE 2107617
gene id: 578455:THITE_2107617
uniprot id: G2QUM6
names: Similarity
messages: Belongs to the VPS54 family.

578455:THITE 2057535
gene id: 578455:THITE_2057535
uniprot id: G2RFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

578455:THITE 118274
gene id: 578455:THITE_118274
uniprot id: G2R0A5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2079905
gene id: 578455:THITE_2079905
uniprot id: G2RB00
names: Similarity
messages: Belongs to the PrpF family.

578455:THITE 2124200
gene id: 578455:THITE_2124200
uniprot id: G2RIE3
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

578455:THITE 2091279
gene id: 578455:THITE_2091279
uniprot id: G2RAU5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

578455:THITE 2155001
gene id: 578455:THITE_2155001
uniprot id: G2R6S2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

578455:THITE 2146721
gene id: 578455:THITE_2146721
uniprot id: G2RCJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

578455:THITE 2107921
gene id: 578455:THITE_2107921
uniprot id: G2QW94
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

578455:THITE 2108176
gene id: 578455:THITE_2108176
uniprot id: G2QXW2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2121081
gene id: 578455:THITE_2121081
uniprot id: G2RED9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

578455:THITE 2037692
gene id: 578455:THITE_2037692
uniprot id: G2QU73
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

578455:THITE 2057389
gene id: 578455:THITE_2057389
uniprot id: G2RD70
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

578455:THITE 2122280
gene id: 578455:THITE_2122280
uniprot id: G2RCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2109235
gene id: 578455:THITE_2109235
uniprot id: G2QUE9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2122070
gene id: 578455:THITE_2122070
uniprot id: G2RFM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2123475
gene id: 578455:THITE_2123475
uniprot id: G2RHG1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114296
gene id: 578455:THITE_2114296
uniprot id: G2QZ62
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

578455:THITE 2109740
gene id: 578455:THITE_2109740
uniprot id: G2QXK9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

578455:THITE 2113315
gene id: 578455:THITE_2113315
uniprot id: G2R2F2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2121598
gene id: 578455:THITE_2121598
uniprot id: G2RF38
names: Caution
names: Function
names: Similarity
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probable lipid hydrolase.

578455:THITE 2108654
gene id: 578455:THITE_2108654
uniprot id: G2QS30
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

578455:THITE 2112257
gene id: 578455:THITE_2112257
uniprot id: G2QY58
names: Function
names: Subcellular Location Annotation
messages: Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.
messages: Membrane
messages: Prevacuolar compartment membrane
messages: trans-Golgi network membrane

578455:THITE 2122394
gene id: 578455:THITE_2122394
uniprot id: G2RD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

578455:THITE 2113501
gene id: 578455:THITE_2113501
uniprot id: G2R2Y7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 136252
gene id: 578455:THITE_136252
uniprot id: G2R6W9
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

578455:THITE 2119256
gene id: 578455:THITE_2119256
uniprot id: G2RBJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

578455:THITE 2122549
gene id: 578455:THITE_2122549
uniprot id: G2RDE7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 157813
gene id: 578455:THITE_157813
uniprot id: G2QWC4
names: Subcellular Location Annotation
messages: Secreted

578455:THITE 2121584
gene id: 578455:THITE_2121584
uniprot id: G2RF33
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

578455:THITE 2056478
gene id: 578455:THITE_2056478
uniprot id: G2RFL0
names: Function
names: Similarity
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.

578455:THITE 2046525
gene id: 578455:THITE_2046525
uniprot id: G2R2Q5
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6A family.

578455:THITE 2116225
gene id: 578455:THITE_2116225
uniprot id: G2R0S2
names: Similarity
messages: Belongs to the MNN1/MNT family.

578455:THITE 2142122
gene id: 578455:THITE_2142122
uniprot id: G2QRB9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2119479
gene id: 578455:THITE_2119479
uniprot id: G2RBV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIMR family. LMBRD1 subfamily.
messages: Lysosome membrane
messages: Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors.

578455:THITE 2118999
gene id: 578455:THITE_2118999
uniprot id: G2RB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

578455:THITE 2108868
gene id: 578455:THITE_2108868
uniprot id: G2QSM1
names: Similarity
messages: Belongs to the RAD52 family.

578455:THITE 2122290
gene id: 578455:THITE_2122290
uniprot id: G2RCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

578455:THITE 2116183
gene id: 578455:THITE_2116183
uniprot id: G2R0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

578455:THITE 2117872
gene id: 578455:THITE_2117872
uniprot id: G2R5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

578455:THITE 2107100
gene id: 578455:THITE_2107100
uniprot id: G2QST8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

578455:THITE 2038627
gene id: 578455:THITE_2038627
uniprot id: G2QVK1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 42348
gene id: 578455:THITE_42348
uniprot id: G2R9N1
names: Function
names: Subcellular Location Annotation
messages: Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.
messages: Nucleus

578455:THITE 132166
gene id: 578455:THITE_132166
uniprot id: G2R7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

578455:THITE 2114358
gene id: 578455:THITE_2114358
uniprot id: G2QZ98
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2122277
gene id: 578455:THITE_2122277
uniprot id: G2RCP3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 126254
gene id: 578455:THITE_126254
uniprot id: G2QY57
names: Similarity
messages: Belongs to the SUN family.

578455:THITE 2119847
gene id: 578455:THITE_2119847
uniprot id: G2R8Y8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2115070
gene id: 578455:THITE_2115070
uniprot id: G2R310
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

578455:THITE 2110783
gene id: 578455:THITE_2110783
uniprot id: G2QUI3
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

578455:THITE 2124488
gene id: 578455:THITE_2124488
uniprot id: G2RFW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

578455:THITE 2112496
gene id: 578455:THITE_2112496
uniprot id: G2QZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

578455:THITE 12695
gene id: 578455:THITE_12695
uniprot id: G2QQK7
names: Similarity
messages: Belongs to the group II decarboxylase family.

578455:THITE 2145970
gene id: 578455:THITE_2145970
uniprot id: G2RAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

578455:THITE 2111701
gene id: 578455:THITE_2111701
uniprot id: G2R380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

578455:THITE 2127665
gene id: 578455:THITE_2127665
uniprot id: G2QZ43
names: Similarity
messages: Belongs to the dpy-30 family.

578455:THITE 2124609
gene id: 578455:THITE_2124609
uniprot id: G2RG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

578455:THITE 2120711
gene id: 578455:THITE_2120711
uniprot id: G2RDG6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

578455:THITE 2122305
gene id: 578455:THITE_2122305
uniprot id: G2RCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

578455:THITE 2112557
gene id: 578455:THITE_2112557
uniprot id: G2QZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus

578455:THITE 2121511
gene id: 578455:THITE_2121511
uniprot id: G2RF02
names: Similarity
messages: Belongs to the HTATSF1 family.

578455:THITE 2106728
gene id: 578455:THITE_2106728
uniprot id: G2QRF9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

578455:THITE 2106257
gene id: 578455:THITE_2106257
uniprot id: G2QWR0
names: Similarity
messages: Belongs to the OSBP family.

578455:THITE 121508
gene id: 578455:THITE_121508
uniprot id: G2R9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2111058
gene id: 578455:THITE_2111058
uniprot id: G2QWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2123551
gene id: 578455:THITE_2123551
uniprot id: G2RHL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

578455:THITE 2116292
gene id: 578455:THITE_2116292
uniprot id: G2R197
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

578455:THITE 66503
gene id: 578455:THITE_66503
uniprot id: G2R4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

578455:THITE 2119395
gene id: 578455:THITE_2119395
uniprot id: G2RBR1
names: Similarity
messages: Belongs to the SAP18 family.

578455:THITE 2049108
gene id: 578455:THITE_2049108
uniprot id: G2R0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

578455:THITE 164359
gene id: 578455:THITE_164359
uniprot id: G2QRB3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2124095
gene id: 578455:THITE_2124095
uniprot id: G2RIA1
names: Similarity
messages: Belongs to the UFD1 family.

578455:THITE 2143619
gene id: 578455:THITE_2143619
uniprot id: G2R3R1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109392
gene id: 578455:THITE_2109392
uniprot id: G2QVA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2115255
gene id: 578455:THITE_2115255
uniprot id: G2R3K2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

578455:THITE 2113759
gene id: 578455:THITE_2113759
uniprot id: G2R478
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

578455:THITE 2112219
gene id: 578455:THITE_2112219
uniprot id: G2QY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

578455:THITE 2119485
gene id: 578455:THITE_2119485
uniprot id: G2RBV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2113839
gene id: 578455:THITE_2113839
uniprot id: G2R4A3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

578455:THITE 2114165
gene id: 578455:THITE_2114165
uniprot id: G2QYA8
names: Similarity
messages: Belongs to the MYBBP1A family.

578455:THITE 2122199
gene id: 578455:THITE_2122199
uniprot id: G2RCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

578455:THITE 2114018
gene id: 578455:THITE_2114018
uniprot id: G2R559
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

578455:THITE 2110888
gene id: 578455:THITE_2110888
uniprot id: G2QUZ4
names: Similarity
messages: Belongs to the tannase family.

578455:THITE 2117536
gene id: 578455:THITE_2117536
uniprot id: G2R880
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

578455:THITE 2111628
gene id: 578455:THITE_2111628
uniprot id: G2R352
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112971
gene id: 578455:THITE_2112971
uniprot id: G2R1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

578455:THITE 2055676
gene id: 578455:THITE_2055676
uniprot id: G2RCI7
names: Similarity
messages: Belongs to the RNase PH family.

578455:THITE 2108326
gene id: 578455:THITE_2108326
uniprot id: G2QQS9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124665
gene id: 578455:THITE_2124665
uniprot id: G2RG81
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

578455:THITE 67951
gene id: 578455:THITE_67951
uniprot id: G2R1G3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

578455:THITE 2169688
gene id: 578455:THITE_2169688
uniprot id: G2QTL2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

578455:THITE 2122857
gene id: 578455:THITE_2122857
uniprot id: G2REH8
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

578455:THITE 2114298
gene id: 578455:THITE_2114298
uniprot id: G2QZ63
names: Similarity
messages: Belongs to the PdxS/SNZ family.

578455:THITE 2106324
gene id: 578455:THITE_2106324
uniprot id: G2QX76
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123200
gene id: 578455:THITE_2123200
uniprot id: G2RGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

578455:THITE 2069968
gene id: 578455:THITE_2069968
uniprot id: G2RF07
names: Similarity
messages: Belongs to the SH3BGR family.

578455:THITE 2112577
gene id: 578455:THITE_2112577
uniprot id: G2QZH8
names: Similarity
messages: Belongs to the AAA ATPase family.

578455:THITE 2114503
gene id: 578455:THITE_2114503
uniprot id: G2R040
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

578455:THITE 2040380
gene id: 578455:THITE_2040380
uniprot id: G2QU13
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107137
gene id: 578455:THITE_2107137
uniprot id: G2QSV9
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2108730
gene id: 578455:THITE_2108730
uniprot id: G2QS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 2114658
gene id: 578455:THITE_2114658
uniprot id: G2R123
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

578455:THITE 2112737
gene id: 578455:THITE_2112737
uniprot id: G2R0D4
names: Similarity
messages: Belongs to the MGR2 family.

578455:THITE 2118518
gene id: 578455:THITE_2118518
uniprot id: G2RA86
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107362
gene id: 578455:THITE_2107362
uniprot id: G2QTR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2120419
gene id: 578455:THITE_2120419
uniprot id: G2RAI4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

578455:THITE 2058384
gene id: 578455:THITE_2058384
uniprot id: G2RHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MOZART1 family.
messages: Part of the gamma-tubulin complex.
messages: Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).
messages: spindle pole body

578455:THITE 2024021
gene id: 578455:THITE_2024021
uniprot id: G2RD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 2113898
gene id: 578455:THITE_2113898
uniprot id: G2R4N8
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2118617
gene id: 578455:THITE_2118617
uniprot id: G2RAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2097063
gene id: 578455:THITE_2097063
uniprot id: G2REE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

578455:THITE 71309
gene id: 578455:THITE_71309
uniprot id: G2RAY0
names: Similarity
messages: Belongs to the SAS10 family.

578455:THITE 50690
gene id: 578455:THITE_50690
uniprot id: G2RHN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

578455:THITE 2124017
gene id: 578455:THITE_2124017
uniprot id: G2RI66
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

578455:THITE 2121926
gene id: 578455:THITE_2121926
uniprot id: G2RFH4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

578455:THITE 2122392
gene id: 578455:THITE_2122392
uniprot id: G2RD11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

578455:THITE 2116053
gene id: 578455:THITE_2116053
uniprot id: G2QZT0
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

578455:THITE 2055536
gene id: 578455:THITE_2055536
uniprot id: G2REJ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2110143
gene id: 578455:THITE_2110143
uniprot id: G2QRS9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

578455:THITE 2111261
gene id: 578455:THITE_2111261
uniprot id: G2R1F5
names: Similarity
messages: Belongs to the citrate synthase family.

578455:THITE 2123881
gene id: 578455:THITE_2123881
uniprot id: G2RI16
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

578455:THITE 2124701
gene id: 578455:THITE_2124701
uniprot id: G2RGA7
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

578455:THITE 48906
gene id: 578455:THITE_48906
uniprot id: G2QV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: cytosol

578455:THITE 2111314
gene id: 578455:THITE_2111314
uniprot id: G2R1U5
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

578455:THITE 2077224
gene id: 578455:THITE_2077224
uniprot id: G2R2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

578455:THITE 2120918
gene id: 578455:THITE_2120918
uniprot id: G2RE24
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

578455:THITE 2108401
gene id: 578455:THITE_2108401
uniprot id: G2QR65
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

578455:THITE 2118175
gene id: 578455:THITE_2118175
uniprot id: G2R913
names: Similarity
messages: Belongs to the peptidase M14 family.

578455:THITE 2144786
gene id: 578455:THITE_2144786
uniprot id: G2R8J6
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2107031
gene id: 578455:THITE_2107031
uniprot id: G2QSF3
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

578455:THITE 2085353
gene id: 578455:THITE_2085353
uniprot id: G2QVQ9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2169528
gene id: 578455:THITE_2169528
uniprot id: G2QUE0
names: Similarity
messages: Belongs to the yippee family.

578455:THITE 2116448
gene id: 578455:THITE_2116448
uniprot id: G2R615
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108647
gene id: 578455:THITE_2108647
uniprot id: G2QS28
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

578455:THITE 2112314
gene id: 578455:THITE_2112314
uniprot id: G2QYJ8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: P1 and P2 exist as dimers at the large ribosomal subunit.

578455:THITE 2108468
gene id: 578455:THITE_2108468
uniprot id: G2QRK5
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

578455:THITE 2107253
gene id: 578455:THITE_2107253
uniprot id: G2QTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

578455:THITE 2113810
gene id: 578455:THITE_2113810
uniprot id: G2R491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

578455:THITE 120899
gene id: 578455:THITE_120899
uniprot id: G2QW89
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121555
gene id: 578455:THITE_2121555
uniprot id: G2RF22
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

578455:THITE 2108560
gene id: 578455:THITE_2108560
uniprot id: G2QRP0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

578455:THITE 70538
gene id: 578455:THITE_70538
uniprot id: G2QS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

578455:THITE 2054748
gene id: 578455:THITE_2054748
uniprot id: G2RAY9
names: Function
names: Similarity
messages: Belongs to the CDC123 family.
messages: Regulates the cell cycle in a nutrient dependent manner.

578455:THITE 2119575
gene id: 578455:THITE_2119575
uniprot id: G2RBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

578455:THITE 2147701
gene id: 578455:THITE_2147701
uniprot id: G2RG47
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 127440
gene id: 578455:THITE_127440
uniprot id: G2REL6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2095256
gene id: 578455:THITE_2095256
uniprot id: G2R3D9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116938
gene id: 578455:THITE_2116938
uniprot id: G2R7C0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

578455:THITE 2085147
gene id: 578455:THITE_2085147
uniprot id: G2QTX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2112730
gene id: 578455:THITE_2112730
uniprot id: G2R0C9
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2114769
gene id: 578455:THITE_2114769
uniprot id: G2R1P9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115555
gene id: 578455:THITE_2115555
uniprot id: G2R4W6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2048922
gene id: 578455:THITE_2048922
uniprot id: G2R3P6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2047529
gene id: 578455:THITE_2047529
uniprot id: G2R3X7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2113333
gene id: 578455:THITE_2113333
uniprot id: G2R2F9
names: Similarity
messages: Belongs to the RutC family.

578455:THITE 2043359
gene id: 578455:THITE_2043359
uniprot id: G2QYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

578455:THITE 2155406
gene id: 578455:THITE_2155406
uniprot id: G2R9Q0
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

578455:THITE 2113829
gene id: 578455:THITE_2113829
uniprot id: G2R498
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

578455:THITE 2113599
gene id: 578455:THITE_2113599
uniprot id: G2R3D4
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

578455:THITE 2121301
gene id: 578455:THITE_2121301
uniprot id: G2RES1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

578455:THITE 124824
gene id: 578455:THITE_124824
uniprot id: G2RH30
names: Similarity
messages: Belongs to the PPase family.

578455:THITE 135495
gene id: 578455:THITE_135495
uniprot id: G2QXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

578455:THITE 2114908
gene id: 578455:THITE_2114908
uniprot id: G2R2I5
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

578455:THITE 2108839
gene id: 578455:THITE_2108839
uniprot id: G2QSK7
names: Similarity
messages: Belongs to the actin family.

578455:THITE 2121865
gene id: 578455:THITE_2121865
uniprot id: G2RFE5
names: Similarity
messages: Belongs to the PPase family.

578455:THITE 2111453
gene id: 578455:THITE_2111453
uniprot id: G2R2C4
names: Function
names: Subcellular Location Annotation
messages: Chromosome
messages: Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.

578455:THITE 2124124
gene id: 578455:THITE_2124124
uniprot id: G2RIB5
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

578455:THITE 2116685
gene id: 578455:THITE_2116685
uniprot id: G2R6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

578455:THITE 2144886
gene id: 578455:THITE_2144886
uniprot id: G2R621
names: Subcellular Location Annotation
messages: Mitochondrion

578455:THITE 2107294
gene id: 578455:THITE_2107294
uniprot id: G2QTD5
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

578455:THITE 2122618
gene id: 578455:THITE_2122618
uniprot id: G2RDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2109522
gene id: 578455:THITE_2109522
uniprot id: G2QWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2114314
gene id: 578455:THITE_2114314
uniprot id: G2QZ69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 2118543
gene id: 578455:THITE_2118543
uniprot id: G2RA97
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118562
gene id: 578455:THITE_2118562
uniprot id: G2RAA8
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

578455:THITE 2123931
gene id: 578455:THITE_2123931
uniprot id: G2RI36
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107058
gene id: 578455:THITE_2107058
uniprot id: G2QSG0
names: Similarity
messages: Belongs to the NAD kinase family.

578455:THITE 2123732
gene id: 578455:THITE_2123732
uniprot id: G2RHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2116446
gene id: 578455:THITE_2116446
uniprot id: G2R614
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

578455:THITE 2119725
gene id: 578455:THITE_2119725
uniprot id: G2RC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.
messages: telomere

578455:THITE 2120154
gene id: 578455:THITE_2120154
uniprot id: G2R9L9
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2083101
gene id: 578455:THITE_2083101
uniprot id: G2RI27
names: Similarity
messages: Belongs to the SEN54 family.

578455:THITE 2115426
gene id: 578455:THITE_2115426
uniprot id: G2R4F0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

578455:THITE 2124112
gene id: 578455:THITE_2124112
uniprot id: G2RIB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

578455:THITE 2107397
gene id: 578455:THITE_2107397
uniprot id: G2QTT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

578455:THITE 2114025
gene id: 578455:THITE_2114025
uniprot id: G2R562
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

578455:THITE 2110554
gene id: 578455:THITE_2110554
uniprot id: G2QTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

578455:THITE 2110199
gene id: 578455:THITE_2110199
uniprot id: G2QRV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2114893
gene id: 578455:THITE_2114893
uniprot id: G2R274
names: Cofactor
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.

578455:THITE 2121217
gene id: 578455:THITE_2121217
uniprot id: G2REN7
names: Similarity
messages: Belongs to the NOC2 family.

578455:THITE 121830
gene id: 578455:THITE_121830
uniprot id: G2RBH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2150001
gene id: 578455:THITE_2150001
uniprot id: G2R1G4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

578455:THITE 2113737
gene id: 578455:THITE_2113737
uniprot id: G2R3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

578455:THITE 2017867
gene id: 578455:THITE_2017867
uniprot id: G2R4X1
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

578455:THITE 2120749
gene id: 578455:THITE_2120749
uniprot id: G2RDJ4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2023894
gene id: 578455:THITE_2023894
uniprot id: G2R7J2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2116866
gene id: 578455:THITE_2116866
uniprot id: G2R783
names: Similarity
messages: Belongs to the MEMO1 family.

578455:THITE 2119642
gene id: 578455:THITE_2119642
uniprot id: G2RC26
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2048305
gene id: 578455:THITE_2048305
uniprot id: G2R2E4
names: Function
names: Similarity
messages: Belongs to the CMC4 family.
messages: Required for the assembly of cytochrome c oxidase.

578455:THITE 2124621
gene id: 578455:THITE_2124621
uniprot id: G2RG28
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

578455:THITE 2082796
gene id: 578455:THITE_2082796
uniprot id: G2RHE6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

578455:THITE 2123869
gene id: 578455:THITE_2123869
uniprot id: G2RI12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

578455:THITE 2054762
gene id: 578455:THITE_2054762
uniprot id: G2RC32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM8 and 3 copies of TIM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

578455:THITE 2068603
gene id: 578455:THITE_2068603
uniprot id: G2RBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

578455:THITE 2066571
gene id: 578455:THITE_2066571
uniprot id: G2R2I8
names: Similarity
messages: Belongs to the PPP phosphatase family.

578455:THITE 2144934
gene id: 578455:THITE_2144934
uniprot id: G2R6E0
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2107561
gene id: 578455:THITE_2107561
uniprot id: G2QU96
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107005
gene id: 578455:THITE_2107005
uniprot id: G2QSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

578455:THITE 2111259
gene id: 578455:THITE_2111259
uniprot id: G2R1F3
names: Similarity
messages: Belongs to the glutamine synthetase family.

578455:THITE 2070309
gene id: 578455:THITE_2070309
uniprot id: G2RC90
names: Similarity
messages: Belongs to the glycosyl hydrolases 36 family.

578455:THITE 2112283
gene id: 578455:THITE_2112283
uniprot id: G2QY72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

578455:THITE 2121340
gene id: 578455:THITE_2121340
uniprot id: G2RET7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

578455:THITE 2069499
gene id: 578455:THITE_2069499
uniprot id: G2RDJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

578455:THITE 2061958
gene id: 578455:THITE_2061958
uniprot id: G2QT92
names: Similarity
messages: Belongs to the peptidase M18 family.

578455:THITE 2148588
gene id: 578455:THITE_2148588
uniprot id: G2QX63
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2169187
gene id: 578455:THITE_2169187
uniprot id: G2QQZ5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

578455:THITE 2148173
gene id: 578455:THITE_2148173
uniprot id: G2RI71
names: Similarity
messages: Belongs to the ATPase delta chain family.

578455:THITE 2106060
gene id: 578455:THITE_2106060
uniprot id: G2QW11
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

578455:THITE 2108172
gene id: 578455:THITE_2108172
uniprot id: G2QXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSH4 family.
messages: Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.
messages: Endosome membrane
messages: Membrane
messages: Vacuole membrane

578455:THITE 2111837
gene id: 578455:THITE_2111837
uniprot id: G2R3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

578455:THITE 2114456
gene id: 578455:THITE_2114456
uniprot id: G2QZQ2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114635
gene id: 578455:THITE_2114635
uniprot id: G2R109
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2115225
gene id: 578455:THITE_2115225
uniprot id: G2R3J0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

578455:THITE 2108621
gene id: 578455:THITE_2108621
uniprot id: G2QS18
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

578455:THITE 2111169
gene id: 578455:THITE_2111169
uniprot id: G2R0U0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2117445
gene id: 578455:THITE_2117445
uniprot id: G2R826
names: Subunit
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.

578455:THITE 2169483
gene id: 578455:THITE_2169483
uniprot id: G2QSZ9
names: Similarity
messages: Belongs to the WD repeat rae1 family.

578455:THITE 2122608
gene id: 578455:THITE_2122608
uniprot id: G2RDM9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114495
gene id: 578455:THITE_2114495
uniprot id: G2R035
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108767
gene id: 578455:THITE_2108767
uniprot id: G2QSH9
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

578455:THITE 2132908
gene id: 578455:THITE_2132908
uniprot id: G2RIC4
names: Similarity
messages: Belongs to the peptidase C48 family.

578455:THITE 2076347
gene id: 578455:THITE_2076347
uniprot id: G2R3Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

578455:THITE 33895
gene id: 578455:THITE_33895
uniprot id: G2QZP9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2055098
gene id: 578455:THITE_2055098
uniprot id: G2R8U6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 119724
gene id: 578455:THITE_119724
uniprot id: G2QYM1
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

578455:THITE 2117458
gene id: 578455:THITE_2117458
uniprot id: G2R835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAM1 family.
messages: Nucleus
messages: kinetochore

578455:THITE 2054227
gene id: 578455:THITE_2054227
uniprot id: G2RAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2145727
gene id: 578455:THITE_2145727
uniprot id: G2R922
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2155589
gene id: 578455:THITE_2155589
uniprot id: G2RBB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

578455:THITE 2122904
gene id: 578455:THITE_2122904
uniprot id: G2RG53
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118715
gene id: 578455:THITE_2118715
uniprot id: G2RAN1
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

578455:THITE 2010889
gene id: 578455:THITE_2010889
uniprot id: G2R6X3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2054379
gene id: 578455:THITE_2054379
uniprot id: G2R9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.
messages: Membrane

578455:THITE 2117975
gene id: 578455:THITE_2117975
uniprot id: G2R6A5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2094470
gene id: 578455:THITE_2094470
uniprot id: G2QSA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: nuclear pore complex

578455:THITE 2118226
gene id: 578455:THITE_2118226
uniprot id: G2R947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

578455:THITE 2040302
gene id: 578455:THITE_2040302
uniprot id: G2QV47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2086741
gene id: 578455:THITE_2086741
uniprot id: G2R4M0
names: Similarity
messages: Belongs to the NEMF family.

578455:THITE 49310
gene id: 578455:THITE_49310
uniprot id: G2RHV6
names: Similarity
messages: Belongs to the R-transferase family.

578455:THITE 2115191
gene id: 578455:THITE_2115191
uniprot id: G2R3H5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

578455:THITE 2155501
gene id: 578455:THITE_2155501
uniprot id: G2RAU9
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2087360
gene id: 578455:THITE_2087360
uniprot id: G2R2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

578455:THITE 2118524
gene id: 578455:THITE_2118524
uniprot id: G2RA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

578455:THITE 2107704
gene id: 578455:THITE_2107704
uniprot id: G2QUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2082381
gene id: 578455:THITE_2082381
uniprot id: G2RE78
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Nucleus

578455:THITE 2051766
gene id: 578455:THITE_2051766
uniprot id: G2R834
names: Similarity
messages: Belongs to the UPF0235 family.

578455:THITE 2088932
gene id: 578455:THITE_2088932
uniprot id: G2R5F3
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

578455:THITE 2075745
gene id: 578455:THITE_2075745
uniprot id: G2R5C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

578455:THITE 2113945
gene id: 578455:THITE_2113945
uniprot id: G2R4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

578455:THITE 2116559
gene id: 578455:THITE_2116559
uniprot id: G2R6Q2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

578455:THITE 2119409
gene id: 578455:THITE_2119409
uniprot id: G2RBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2106263
gene id: 578455:THITE_2106263
uniprot id: G2QWR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

578455:THITE 2106561
gene id: 578455:THITE_2106561
uniprot id: G2QQL6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 128217
gene id: 578455:THITE_128217
uniprot id: G2R766
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

578455:THITE 2052159
gene id: 578455:THITE_2052159
uniprot id: G2R6Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

578455:THITE 2107120
gene id: 578455:THITE_2107120
uniprot id: G2QSU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2119956
gene id: 578455:THITE_2119956
uniprot id: G2R987
names: Similarity
messages: Belongs to the alpha-actinin family.

578455:THITE 2107126
gene id: 578455:THITE_2107126
uniprot id: G2QSV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

578455:THITE 2083064
gene id: 578455:THITE_2083064
uniprot id: G2RHY8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

578455:THITE 2120001
gene id: 578455:THITE_2120001
uniprot id: G2R9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2116333
gene id: 578455:THITE_2116333
uniprot id: G2R5G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

578455:THITE 2107238
gene id: 578455:THITE_2107238
uniprot id: G2QTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2117422
gene id: 578455:THITE_2117422
uniprot id: G2R816
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

578455:THITE 2119532
gene id: 578455:THITE_2119532
uniprot id: G2RBX5
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107393
gene id: 578455:THITE_2107393
uniprot id: G2QTT2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

578455:THITE 2113597
gene id: 578455:THITE_2113597
uniprot id: G2R3D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

578455:THITE 2122615
gene id: 578455:THITE_2122615
uniprot id: G2RDN2
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

578455:THITE 2123577
gene id: 578455:THITE_2123577
uniprot id: G2RHM7
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2120612
gene id: 578455:THITE_2120612
uniprot id: G2RCX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

578455:THITE 2133195
gene id: 578455:THITE_2133195
uniprot id: G2RGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Membrane

578455:THITE 2094798
gene id: 578455:THITE_2094798
uniprot id: G2R385
names: Similarity
messages: Belongs to the eIF-1A family.

578455:THITE 2156634
gene id: 578455:THITE_2156634
uniprot id: G2RHK6
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

578455:THITE 2053546
gene id: 578455:THITE_2053546
uniprot id: G2R9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

578455:THITE 2116109
gene id: 578455:THITE_2116109
uniprot id: G2QZW1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

578455:THITE 2141215
gene id: 578455:THITE_2141215
uniprot id: G2QVP7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 160552
gene id: 578455:THITE_160552
uniprot id: G2R7A1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

578455:THITE 2111195
gene id: 578455:THITE_2111195
uniprot id: G2R1B9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

578455:THITE 2110036
gene id: 578455:THITE_2110036
uniprot id: G2QRB6
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2108322
gene id: 578455:THITE_2108322
uniprot id: G2QQS4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 2120878
gene id: 578455:THITE_2120878
uniprot id: G2RE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pym family.
messages: Cytoplasm

578455:THITE 2108695
gene id: 578455:THITE_2108695
uniprot id: G2QS45
names: Similarity
messages: Belongs to the malic enzymes family.

578455:THITE 2113249
gene id: 578455:THITE_2113249
uniprot id: G2R220
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

578455:THITE 112329
gene id: 578455:THITE_112329
uniprot id: G2QRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

578455:THITE 170174
gene id: 578455:THITE_170174
uniprot id: G2QYT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2119463
gene id: 578455:THITE_2119463
uniprot id: G2RBU2
names: Similarity
messages: Belongs to the SIN1 family.

578455:THITE 2120606
gene id: 578455:THITE_2120606
uniprot id: G2RCV4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

578455:THITE 2052988
gene id: 578455:THITE_2052988
uniprot id: G2R9G1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2080037
gene id: 578455:THITE_2080037
uniprot id: G2RBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

578455:THITE 13184
gene id: 578455:THITE_13184
uniprot id: G2RIB0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2124869
gene id: 578455:THITE_2124869
uniprot id: G2RH40
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

578455:THITE 2120621
gene id: 578455:THITE_2120621
uniprot id: G2RCX9
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2108525
gene id: 578455:THITE_2108525
uniprot id: G2QRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2045005
gene id: 578455:THITE_2045005
uniprot id: G2R540
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

578455:THITE 2156279
gene id: 578455:THITE_2156279
uniprot id: G2RFL7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

578455:THITE 2109119
gene id: 578455:THITE_2109119
uniprot id: G2QTJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.
messages: Membrane

578455:THITE 2124642
gene id: 578455:THITE_2124642
uniprot id: G2RG64
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

578455:THITE 2106794
gene id: 578455:THITE_2106794
uniprot id: G2QRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

578455:THITE 2113589
gene id: 578455:THITE_2113589
uniprot id: G2R3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

578455:THITE 2087407
gene id: 578455:THITE_2087407
uniprot id: G2R3C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2111334
gene id: 578455:THITE_2111334
uniprot id: G2R1W7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

578455:THITE 2130676
gene id: 578455:THITE_2130676
uniprot id: G2RB20
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

578455:THITE 2111030
gene id: 578455:THITE_2111030
uniprot id: G2QWG3
names: Similarity
messages: Belongs to the isochorismatase family.

578455:THITE 2141944
gene id: 578455:THITE_2141944
uniprot id: G2QX01
names: Similarity
messages: Belongs to the band 7/mec-2 family.

578455:THITE 71850
gene id: 578455:THITE_71850
uniprot id: G2RC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Nucleus

578455:THITE 2116093
gene id: 578455:THITE_2116093
uniprot id: G2QZV3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116301
gene id: 578455:THITE_2116301
uniprot id: G2R8J2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2124091
gene id: 578455:THITE_2124091
uniprot id: G2RI99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

578455:THITE 57424
gene id: 578455:THITE_57424
uniprot id: G2QXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

578455:THITE 2114235
gene id: 578455:THITE_2114235
uniprot id: G2QYS3
names: Function
names: Subunit
messages: Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
messages: Interacts with lipid droplet proteins.

578455:THITE 2124492
gene id: 578455:THITE_2124492
uniprot id: G2RFW2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2112481
gene id: 578455:THITE_2112481
uniprot id: G2QZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

578455:THITE 2109887
gene id: 578455:THITE_2109887
uniprot id: G2QQU4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

578455:THITE 2086297
gene id: 578455:THITE_2086297
uniprot id: G2QX36
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109946
gene id: 578455:THITE_2109946
uniprot id: G2QQW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

578455:THITE 2118919
gene id: 578455:THITE_2118919
uniprot id: G2RB26
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2093391
gene id: 578455:THITE_2093391
uniprot id: G2RGK6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

578455:THITE 2112133
gene id: 578455:THITE_2112133
uniprot id: G2R505
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

578455:THITE 2107374
gene id: 578455:THITE_2107374
uniprot id: G2QTS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
messages: Membrane
messages: Vacuole membrane

578455:THITE 2151251
gene id: 578455:THITE_2151251
uniprot id: G2RAV1
names: Similarity
messages: Belongs to the WD repeat rae1 family.

578455:THITE 2119090
gene id: 578455:THITE_2119090
uniprot id: G2RBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

578455:THITE 2148269
gene id: 578455:THITE_2148269
uniprot id: G2RIH2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

578455:THITE 2065655
gene id: 578455:THITE_2065655
uniprot id: G2R2H7
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

578455:THITE 72917
gene id: 578455:THITE_72917
uniprot id: G2RFF3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

578455:THITE 2144812
gene id: 578455:THITE_2144812
uniprot id: G2R5G4
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2116354
gene id: 578455:THITE_2116354
uniprot id: G2R5I3
names: Similarity
messages: Belongs to the FAH family.

578455:THITE 2053799
gene id: 578455:THITE_2053799
uniprot id: G2RB14
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

578455:THITE 2042402
gene id: 578455:THITE_2042402
uniprot id: G2QVV2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120357
gene id: 578455:THITE_2120357
uniprot id: G2RA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

578455:THITE 2115044
gene id: 578455:THITE_2115044
uniprot id: G2R2Z7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

578455:THITE 2109909
gene id: 578455:THITE_2109909
uniprot id: G2QQV1
names: Similarity
messages: Belongs to the sorting nexin family.

578455:THITE 2123161
gene id: 578455:THITE_2123161
uniprot id: G2RGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

578455:THITE 2106380
gene id: 578455:THITE_2106380
uniprot id: G2QXA3
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 134572
gene id: 578455:THITE_134572
uniprot id: G2RBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 37555
gene id: 578455:THITE_37555
uniprot id: G2R087
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbohydrate esterase 1 (CE1) family.
messages: Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
messages: Secreted

578455:THITE 2111503
gene id: 578455:THITE_2111503
uniprot id: G2R2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

578455:THITE 2042644
gene id: 578455:THITE_2042644
uniprot id: G2QSF0
names: Similarity
messages: Belongs to the DeSI family.

578455:THITE 2113774
gene id: 578455:THITE_2113774
uniprot id: G2R483
names: Similarity
messages: Belongs to the enolase family.

578455:THITE 2145927
gene id: 578455:THITE_2145927
uniprot id: G2RAK6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117183
gene id: 578455:THITE_2117183
uniprot id: G2R7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

578455:THITE 2122443
gene id: 578455:THITE_2122443
uniprot id: G2RD96
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113371
gene id: 578455:THITE_2113371
uniprot id: G2R2H3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

578455:THITE 2171450
gene id: 578455:THITE_2171450
uniprot id: G2RE80
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family. G(q) subfamily.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

578455:THITE 128412
gene id: 578455:THITE_128412
uniprot id: G2R5D2
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2124640
gene id: 578455:THITE_2124640
uniprot id: G2RG62
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

578455:THITE 2143111
gene id: 578455:THITE_2143111
uniprot id: G2QYJ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 123781
gene id: 578455:THITE_123781
uniprot id: G2QT87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

578455:THITE 2119782
gene id: 578455:THITE_2119782
uniprot id: G2R8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2074670
gene id: 578455:THITE_2074670
uniprot id: G2QTG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

578455:THITE 2120048
gene id: 578455:THITE_2120048
uniprot id: G2R9I4
names: Similarity
messages: Belongs to the PIAS family.

578455:THITE 2082556
gene id: 578455:THITE_2082556
uniprot id: G2RGN9
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

578455:THITE 53694
gene id: 578455:THITE_53694
uniprot id: G2R7D4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2116815
gene id: 578455:THITE_2116815
uniprot id: G2R761
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure
messages: Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

578455:THITE 164568
gene id: 578455:THITE_164568
uniprot id: G2QUZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

578455:THITE 2112371
gene id: 578455:THITE_2112371
uniprot id: G2QYM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
messages: Mitochondrion inner membrane

578455:THITE 2122881
gene id: 578455:THITE_2122881
uniprot id: G2REJ2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2073944
gene id: 578455:THITE_2073944
uniprot id: G2QVL0
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

578455:THITE 60698
gene id: 578455:THITE_60698
uniprot id: G2RAI8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

578455:THITE 2112373
gene id: 578455:THITE_2112373
uniprot id: G2QYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

578455:THITE 2129403
gene id: 578455:THITE_2129403
uniprot id: G2R5S2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 72918
gene id: 578455:THITE_72918
uniprot id: G2RFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 115795
gene id: 578455:THITE_115795
uniprot id: G2QRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 73286
gene id: 578455:THITE_73286
uniprot id: G2REQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2120838
gene id: 578455:THITE_2120838
uniprot id: G2RDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

578455:THITE 2112901
gene id: 578455:THITE_2112901
uniprot id: G2R0Y9
names: Similarity
messages: Belongs to the phosducin family.

578455:THITE 2140706
gene id: 578455:THITE_2140706
uniprot id: G2QQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
messages: Homodimer.
messages: Preautophagosomal structure

578455:THITE 2106727
gene id: 578455:THITE_2106727
uniprot id: G2QRF8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2153454
gene id: 578455:THITE_2153454
uniprot id: G2QY26
names: Similarity
messages: Belongs to the cytochrome b5 family.

578455:THITE 2108375
gene id: 578455:THITE_2108375
uniprot id: G2QR56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2113006
gene id: 578455:THITE_2113006
uniprot id: G2R1H8
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

578455:THITE 2119863
gene id: 578455:THITE_2119863
uniprot id: G2R8Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2117123
gene id: 578455:THITE_2117123
uniprot id: G2R7N3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

578455:THITE 41229
gene id: 578455:THITE_41229
uniprot id: G2QUQ1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2110793
gene id: 578455:THITE_2110793
uniprot id: G2QUI9
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

578455:THITE 2112905
gene id: 578455:THITE_2112905
uniprot id: G2R0Z0
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

578455:THITE 2113397
gene id: 578455:THITE_2113397
uniprot id: G2R2U1
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

578455:THITE 2106359
gene id: 578455:THITE_2106359
uniprot id: G2QX92
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2116905
gene id: 578455:THITE_2116905
uniprot id: G2R7A0
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

578455:THITE 122351
gene id: 578455:THITE_122351
uniprot id: G2REK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

578455:THITE 2069428
gene id: 578455:THITE_2069428
uniprot id: G2RDE8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115752
gene id: 578455:THITE_2115752
uniprot id: G2QYD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuole membrane

578455:THITE 2115850
gene id: 578455:THITE_2115850
uniprot id: G2QYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: nuclear pore complex

578455:THITE 2109729
gene id: 578455:THITE_2109729
uniprot id: G2QXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

578455:THITE 2171303
gene id: 578455:THITE_2171303
uniprot id: G2RF78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

578455:THITE 37669
gene id: 578455:THITE_37669
uniprot id: G2R3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

578455:THITE 2030466
gene id: 578455:THITE_2030466
uniprot id: G2R8U3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2123227
gene id: 578455:THITE_2123227
uniprot id: G2RH08
names: Function
names: Similarity
messages: Belongs to the POA1 family.
messages: Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.

578455:THITE 2153730
gene id: 578455:THITE_2153730
uniprot id: G2R0T6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2119434
gene id: 578455:THITE_2119434
uniprot id: G2RBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis.
messages: nucleolus

578455:THITE 2171161
gene id: 578455:THITE_2171161
uniprot id: G2RDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

578455:THITE 2114044
gene id: 578455:THITE_2114044
uniprot id: G2R568
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

578455:THITE 2154157
gene id: 578455:THITE_2154157
uniprot id: G2R1G8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

578455:THITE 2109621
gene id: 578455:THITE_2109621
uniprot id: G2QX21
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

578455:THITE 2111773
gene id: 578455:THITE_2111773
uniprot id: G2R3L5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122649
gene id: 578455:THITE_2122649
uniprot id: G2RDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

578455:THITE 2106704
gene id: 578455:THITE_2106704
uniprot id: G2QR37
names: Similarity
messages: Belongs to the importin alpha family.

578455:THITE 2124687
gene id: 578455:THITE_2124687
uniprot id: G2RG97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

578455:THITE 2119503
gene id: 578455:THITE_2119503
uniprot id: G2RBW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

578455:THITE 2155823
gene id: 578455:THITE_2155823
uniprot id: G2R9J6
names: Subcellular Location Annotation
messages: Membrane
messages: Preautophagosomal structure membrane

578455:THITE 2112862
gene id: 578455:THITE_2112862
uniprot id: G2R0X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

578455:THITE 2048914
gene id: 578455:THITE_2048914
uniprot id: G2R4H2
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.

578455:THITE 2143750
gene id: 578455:THITE_2143750
uniprot id: G2R4T1
names: Similarity
messages: Belongs to the fgaFS/easG family.

578455:THITE 29668
gene id: 578455:THITE_29668
uniprot id: G2R054
names: Similarity
names: Subunit
messages: Belongs to the EXO5 family.
messages: Monomer.

578455:THITE 2170761
gene id: 578455:THITE_2170761
uniprot id: G2R694
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2072718
gene id: 578455:THITE_2072718
uniprot id: G2QT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

578455:THITE 2119339
gene id: 578455:THITE_2119339
uniprot id: G2RBN1
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

578455:THITE 2153409
gene id: 578455:THITE_2153409
uniprot id: G2QXI7
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

578455:THITE 45297
gene id: 578455:THITE_45297
uniprot id: G2RFB7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2123600
gene id: 578455:THITE_2123600
uniprot id: G2RHP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

578455:THITE 2093404
gene id: 578455:THITE_2093404
uniprot id: G2RGL6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2123516
gene id: 578455:THITE_2123516
uniprot id: G2RHJ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

578455:THITE 2141374
gene id: 578455:THITE_2141374
uniprot id: G2QXW7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2155027
gene id: 578455:THITE_2155027
uniprot id: G2R722
names: Function
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.

578455:THITE 2129674
gene id: 578455:THITE_2129674
uniprot id: G2R7D3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111035
gene id: 578455:THITE_2111035
uniprot id: G2QWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

578455:THITE 2107870
gene id: 578455:THITE_2107870
uniprot id: G2QVP2
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.

578455:THITE 2121126
gene id: 578455:THITE_2121126
uniprot id: G2REG1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 154425
gene id: 578455:THITE_154425
uniprot id: G2QV50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

578455:THITE 2077788
gene id: 578455:THITE_2077788
uniprot id: G2QYP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the mannitol dehydrogenase family.
messages: Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.
messages: Monomer.

578455:THITE 2113929
gene id: 578455:THITE_2113929
uniprot id: G2R4Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

578455:THITE 2049403
gene id: 578455:THITE_2049403
uniprot id: G2R1V2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2142696
gene id: 578455:THITE_2142696
uniprot id: G2R1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 55565
gene id: 578455:THITE_55565
uniprot id: G2R3R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

578455:THITE 2121819
gene id: 578455:THITE_2121819
uniprot id: G2RFC5
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

578455:THITE 2144318
gene id: 578455:THITE_2144318
uniprot id: G2R3X8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

578455:THITE 130453
gene id: 578455:THITE_130453
uniprot id: G2RC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

578455:THITE 46397
gene id: 578455:THITE_46397
uniprot id: G2RD99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anthrone oxygenase family.
messages: Membrane

578455:THITE 2038308
gene id: 578455:THITE_2038308
uniprot id: G2QWK3
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2122400
gene id: 578455:THITE_2122400
uniprot id: G2RD15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2123037
gene id: 578455:THITE_2123037
uniprot id: G2RGM6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 2144762
gene id: 578455:THITE_2144762
uniprot id: G2R182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

578455:THITE 2117764
gene id: 578455:THITE_2117764
uniprot id: G2R5K7
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

578455:THITE 2120389
gene id: 578455:THITE_2120389
uniprot id: G2RAG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

578455:THITE 2117298
gene id: 578455:THITE_2117298
uniprot id: G2R7V6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

578455:THITE 2120199
gene id: 578455:THITE_2120199
uniprot id: G2R9T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Nucleus

578455:THITE 2113858
gene id: 578455:THITE_2113858
uniprot id: G2R4B5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

578455:THITE 2109035
gene id: 578455:THITE_2109035
uniprot id: G2QTF9
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

578455:THITE 2116310
gene id: 578455:THITE_2116310
uniprot id: G2R8L0
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

578455:THITE 2082502
gene id: 578455:THITE_2082502
uniprot id: G2RGF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

578455:THITE 2131091
gene id: 578455:THITE_2131091
uniprot id: G2R992
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

578455:THITE 2119341
gene id: 578455:THITE_2119341
uniprot id: G2RBN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

578455:THITE 2123254
gene id: 578455:THITE_2123254
uniprot id: G2RH21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

578455:THITE 2124537
gene id: 578455:THITE_2124537
uniprot id: G2RFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

578455:THITE 2119921
gene id: 578455:THITE_2119921
uniprot id: G2R974
names: Similarity
messages: Belongs to the TCTP family.

578455:THITE 2087754
gene id: 578455:THITE_2087754
uniprot id: G2QYT9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 68241
gene id: 578455:THITE_68241
uniprot id: G2QZ01
names: Similarity
messages: Belongs to the TPA1 family.

578455:THITE 2114722
gene id: 578455:THITE_2114722
uniprot id: G2R1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2111338
gene id: 578455:THITE_2111338
uniprot id: G2R277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

578455:THITE 2112388
gene id: 578455:THITE_2112388
uniprot id: G2QYM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

578455:THITE 2124636
gene id: 578455:THITE_2124636
uniprot id: G2RG46
names: Similarity
messages: Belongs to the DOCK family.

578455:THITE 2121546
gene id: 578455:THITE_2121546
uniprot id: G2RF19
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

578455:THITE 48711
gene id: 578455:THITE_48711
uniprot id: G2QRB7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2114381
gene id: 578455:THITE_2114381
uniprot id: G2QZL4
names: Similarity
messages: Belongs to the DCC1 family.

578455:THITE 2120735
gene id: 578455:THITE_2120735
uniprot id: G2RDI7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120569
gene id: 578455:THITE_2120569
uniprot id: G2RCM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

578455:THITE 2119065
gene id: 578455:THITE_2119065
uniprot id: G2RB95
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

578455:THITE 2112060
gene id: 578455:THITE_2112060
uniprot id: G2R4L1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2150497
gene id: 578455:THITE_2150497
uniprot id: G2R3Y3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

578455:THITE 2146125
gene id: 578455:THITE_2146125
uniprot id: G2RBD1
names: Similarity
messages: Belongs to the ATG16 family.

578455:THITE 2121725
gene id: 578455:THITE_2121725
uniprot id: G2RF86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

578455:THITE 2107313
gene id: 578455:THITE_2107313
uniprot id: G2QTQ1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

578455:THITE 2112663
gene id: 578455:THITE_2112663
uniprot id: G2QZZ2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2156915
gene id: 578455:THITE_2156915
uniprot id: G2RGJ8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

578455:THITE 2109432
gene id: 578455:THITE_2109432
uniprot id: G2QVQ7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

578455:THITE 120736
gene id: 578455:THITE_120736
uniprot id: G2QU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2123458
gene id: 578455:THITE_2123458
uniprot id: G2RHF0
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

578455:THITE 2124632
gene id: 578455:THITE_2124632
uniprot id: G2RG42
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

578455:THITE 2114131
gene id: 578455:THITE_2114131
uniprot id: G2QY96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

578455:THITE 2053567
gene id: 578455:THITE_2053567
uniprot id: G2RB18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

578455:THITE 2124057
gene id: 578455:THITE_2124057
uniprot id: G2RI82
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

578455:THITE 2117874
gene id: 578455:THITE_2117874
uniprot id: G2R5Y6
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.

578455:THITE 2121674
gene id: 578455:THITE_2121674
uniprot id: G2RF67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

578455:THITE 35493
gene id: 578455:THITE_35493
uniprot id: G2R0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
messages: Secreted

578455:THITE 2113595
gene id: 578455:THITE_2113595
uniprot id: G2R3D2
names: Similarity
messages: Belongs to the lipin family.

578455:THITE 2111103
gene id: 578455:THITE_2111103
uniprot id: G2QWJ5
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2077551
gene id: 578455:THITE_2077551
uniprot id: G2R499
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

578455:THITE 2118971
gene id: 578455:THITE_2118971
uniprot id: G2RB47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2110866
gene id: 578455:THITE_2110866
uniprot id: G2QUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2115639
gene id: 578455:THITE_2115639
uniprot id: G2R5B1
names: Subcellular Location Annotation
messages: Mitochondrion

578455:THITE 2170318
gene id: 578455:THITE_2170318
uniprot id: G2R147
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

578455:THITE 2110738
gene id: 578455:THITE_2110738
uniprot id: G2QU57
names: Similarity
messages: Belongs to the MYG1 family.

578455:THITE 2111556
gene id: 578455:THITE_2111556
uniprot id: G2R2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

578455:THITE 2122295
gene id: 578455:THITE_2122295
uniprot id: G2RCQ5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114740
gene id: 578455:THITE_2114740
uniprot id: G2R1N4
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

578455:THITE 2111749
gene id: 578455:THITE_2111749
uniprot id: G2R3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2086300
gene id: 578455:THITE_2086300
uniprot id: G2QX40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2115964
gene id: 578455:THITE_2115964
uniprot id: G2QZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2171246
gene id: 578455:THITE_2171246
uniprot id: G2RER4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120692
gene id: 578455:THITE_2120692
uniprot id: G2RDF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2109894
gene id: 578455:THITE_2109894
uniprot id: G2QQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2117266
gene id: 578455:THITE_2117266
uniprot id: G2R7T8
names: Similarity
messages: Belongs to the AAA ATPase family.

578455:THITE 2122776
gene id: 578455:THITE_2122776
uniprot id: G2RE79
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

578455:THITE 2110908
gene id: 578455:THITE_2110908
uniprot id: G2QV21
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

578455:THITE 2115421
gene id: 578455:THITE_2115421
uniprot id: G2R4E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.
messages: telomere

578455:THITE 2120827
gene id: 578455:THITE_2120827
uniprot id: G2RDT1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2114350
gene id: 578455:THITE_2114350
uniprot id: G2QZ96
names: Similarity
messages: Belongs to the PPP phosphatase family.

578455:THITE 2169415
gene id: 578455:THITE_2169415
uniprot id: G2QQR3
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

578455:THITE 2121905
gene id: 578455:THITE_2121905
uniprot id: G2RFG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2106516
gene id: 578455:THITE_2106516
uniprot id: G2QQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

578455:THITE 2114926
gene id: 578455:THITE_2114926
uniprot id: G2R2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

578455:THITE 54110
gene id: 578455:THITE_54110
uniprot id: G2QZD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

578455:THITE 2110665
gene id: 578455:THITE_2110665
uniprot id: G2QU28
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

578455:THITE 2117290
gene id: 578455:THITE_2117290
uniprot id: G2R7V2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124204
gene id: 578455:THITE_2124204
uniprot id: G2RIE4
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

578455:THITE 2145295
gene id: 578455:THITE_2145295
uniprot id: G2R7Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2118080
gene id: 578455:THITE_2118080
uniprot id: G2R6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

578455:THITE 2055435
gene id: 578455:THITE_2055435
uniprot id: G2RD22
names: Similarity
messages: Belongs to the amidase family.

578455:THITE 2110765
gene id: 578455:THITE_2110765
uniprot id: G2QUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

578455:THITE 2147230
gene id: 578455:THITE_2147230
uniprot id: G2RF89
names: Similarity
messages: Belongs to the RRN3 family.

578455:THITE 2171659
gene id: 578455:THITE_2171659
uniprot id: G2RIG2
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

578455:THITE 2122873
gene id: 578455:THITE_2122873
uniprot id: G2REI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 2124454
gene id: 578455:THITE_2124454
uniprot id: G2RFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2112039
gene id: 578455:THITE_2112039
uniprot id: G2R4K1
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2038446
gene id: 578455:THITE_2038446
uniprot id: G2QTJ8
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2051761
gene id: 578455:THITE_2051761
uniprot id: G2R769
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107643
gene id: 578455:THITE_2107643
uniprot id: G2QUN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 117234
gene id: 578455:THITE_117234
uniprot id: G2R6V4
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2124337
gene id: 578455:THITE_2124337
uniprot id: G2RFQ3
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 11494
gene id: 578455:THITE_11494
uniprot id: G2QZR7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2110890
gene id: 578455:THITE_2110890
uniprot id: G2QUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2106250
gene id: 578455:THITE_2106250
uniprot id: G2QWQ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2117138
gene id: 578455:THITE_2117138
uniprot id: G2R7P1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2119948
gene id: 578455:THITE_2119948
uniprot id: G2R984
names: Similarity
messages: Belongs to the SH3RF family.

578455:THITE 2117150
gene id: 578455:THITE_2117150
uniprot id: G2R7P6
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

578455:THITE 2170230
gene id: 578455:THITE_2170230
uniprot id: G2R594
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

578455:THITE 2112355
gene id: 578455:THITE_2112355
uniprot id: G2QYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

578455:THITE 2064729
gene id: 578455:THITE_2064729
uniprot id: G2R3Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C1D family.
messages: Nucleus
messages: Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.

578455:THITE 2075465
gene id: 578455:THITE_2075465
uniprot id: G2R3H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

578455:THITE 2061232
gene id: 578455:THITE_2061232
uniprot id: G2QU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

578455:THITE 2120081
gene id: 578455:THITE_2120081
uniprot id: G2R9J3
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

578455:THITE 2123767
gene id: 578455:THITE_2123767
uniprot id: G2RHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 109093
gene id: 578455:THITE_109093
uniprot id: G2QXX3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 36172
gene id: 578455:THITE_36172
uniprot id: G2QZ68
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

578455:THITE 2117766
gene id: 578455:THITE_2117766
uniprot id: G2R5L3
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

578455:THITE 2113532
gene id: 578455:THITE_2113532
uniprot id: G2R3A8
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

578455:THITE 2107546
gene id: 578455:THITE_2107546
uniprot id: G2QU90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.

578455:THITE 2170924
gene id: 578455:THITE_2170924
uniprot id: G2RBF8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

578455:THITE 2108459
gene id: 578455:THITE_2108459
uniprot id: G2QR94
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2093424
gene id: 578455:THITE_2093424
uniprot id: G2RGU0
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2114956
gene id: 578455:THITE_2114956
uniprot id: G2R2K5
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2011569
gene id: 578455:THITE_2011569
uniprot id: G2RG72
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2122016
gene id: 578455:THITE_2122016
uniprot id: G2RFL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

578455:THITE 2151093
gene id: 578455:THITE_2151093
uniprot id: G2R6U3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2109873
gene id: 578455:THITE_2109873
uniprot id: G2QQT8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2121983
gene id: 578455:THITE_2121983
uniprot id: G2RFJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Secreted

578455:THITE 2117173
gene id: 578455:THITE_2117173
uniprot id: G2R7Q2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 67036
gene id: 578455:THITE_67036
uniprot id: G2R043
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

578455:THITE 2055849
gene id: 578455:THITE_2055849
uniprot id: G2RCD4
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2119654
gene id: 578455:THITE_2119654
uniprot id: G2RC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

578455:THITE 2106236
gene id: 578455:THITE_2106236
uniprot id: G2QWQ1
names: Similarity
messages: Belongs to the CCZ1 family.

578455:THITE 2123651
gene id: 578455:THITE_2123651
uniprot id: G2RHR3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

578455:THITE 2119201
gene id: 578455:THITE_2119201
uniprot id: G2RBG5
names: Function
names: Similarity
messages: Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.
messages: Belongs to the rad9 family.

578455:THITE 2110058
gene id: 578455:THITE_2110058
uniprot id: G2QRD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

578455:THITE 2122967
gene id: 578455:THITE_2122967
uniprot id: G2RGE2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2153318
gene id: 578455:THITE_2153318
uniprot id: G2QUF0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

578455:THITE 2153879
gene id: 578455:THITE_2153879
uniprot id: G2R3M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

578455:THITE 2112602
gene id: 578455:THITE_2112602
uniprot id: G2QZJ3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2170215
gene id: 578455:THITE_2170215
uniprot id: G2R4S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2122134
gene id: 578455:THITE_2122134
uniprot id: G2RCA0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

578455:THITE 2118935
gene id: 578455:THITE_2118935
uniprot id: G2RB32
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2111481
gene id: 578455:THITE_2111481
uniprot id: G2R2P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

578455:THITE 45545
gene id: 578455:THITE_45545
uniprot id: G2REG7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109651
gene id: 578455:THITE_2109651
uniprot id: G2QXH5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

578455:THITE 2124040
gene id: 578455:THITE_2124040
uniprot id: G2RI72
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

578455:THITE 2116842
gene id: 578455:THITE_2116842
uniprot id: G2R774
names: Function
names: Similarity
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.

578455:THITE 2117733
gene id: 578455:THITE_2117733
uniprot id: G2R8R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

578455:THITE 2071253
gene id: 578455:THITE_2071253
uniprot id: G2RHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

578455:THITE 2118458
gene id: 578455:THITE_2118458
uniprot id: G2RA14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

578455:THITE 2057357
gene id: 578455:THITE_2057357
uniprot id: G2RF28
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2106347
gene id: 578455:THITE_2106347
uniprot id: G2QX86
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

578455:THITE 2113209
gene id: 578455:THITE_2113209
uniprot id: G2R207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

578455:THITE 2169356
gene id: 578455:THITE_2169356
uniprot id: G2QVN3
names: Similarity
messages: Belongs to the APC13 family.

578455:THITE 2114595
gene id: 578455:THITE_2114595
uniprot id: G2R0K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2095468
gene id: 578455:THITE_2095468
uniprot id: G2R042
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

578455:THITE 2112208
gene id: 578455:THITE_2112208
uniprot id: G2QY36
names: Similarity
messages: Belongs to the activator 1 small subunits family.

578455:THITE 2120126
gene id: 578455:THITE_2120126
uniprot id: G2R9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2120734
gene id: 578455:THITE_2120734
uniprot id: G2RDI5
names: Similarity
messages: Belongs to the PhyH family.

578455:THITE 2123791
gene id: 578455:THITE_2123791
uniprot id: G2RHX9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

578455:THITE 118259
gene id: 578455:THITE_118259
uniprot id: G2R0N1
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2114003
gene id: 578455:THITE_2114003
uniprot id: G2R551
names: Similarity
messages: Belongs to the FAH family.

578455:THITE 2108862
gene id: 578455:THITE_2108862
uniprot id: G2QSM0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

578455:THITE 154681
gene id: 578455:THITE_154681
uniprot id: G2QXG0
names: Similarity
messages: Belongs to the complex I LYR family.

578455:THITE 66557
gene id: 578455:THITE_66557
uniprot id: G2R3X5
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

578455:THITE 2121779
gene id: 578455:THITE_2121779
uniprot id: G2RFA6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2090020
gene id: 578455:THITE_2090020
uniprot id: G2R6T0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2145149
gene id: 578455:THITE_2145149
uniprot id: G2R7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

578455:THITE 2121911
gene id: 578455:THITE_2121911
uniprot id: G2RFG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

578455:THITE 2108478
gene id: 578455:THITE_2108478
uniprot id: G2QRK9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 2106889
gene id: 578455:THITE_2106889
uniprot id: G2QRY6
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

578455:THITE 2108107
gene id: 578455:THITE_2108107
uniprot id: G2QXS9
names: Similarity
messages: Belongs to the peptidase S14 family.

578455:THITE 135989
gene id: 578455:THITE_135989
uniprot id: G2RHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2122133
gene id: 578455:THITE_2122133
uniprot id: G2RC99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

578455:THITE 2115331
gene id: 578455:THITE_2115331
uniprot id: G2R407
names: Similarity
messages: Belongs to the bystin family.

578455:THITE 2114865
gene id: 578455:THITE_2114865
uniprot id: G2R257
names: Similarity
messages: Belongs to the TRL1 family.

578455:THITE 2073277
gene id: 578455:THITE_2073277
uniprot id: G2QR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2114627
gene id: 578455:THITE_2114627
uniprot id: G2R102
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

578455:THITE 2114160
gene id: 578455:THITE_2114160
uniprot id: G2QYA7
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

578455:THITE 2153191
gene id: 578455:THITE_2153191
uniprot id: G2QS35
names: Subcellular Location Annotation
messages: Membrane
messages: Preautophagosomal structure membrane

578455:THITE 65565
gene id: 578455:THITE_65565
uniprot id: G2R7C9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

578455:THITE 2123607
gene id: 578455:THITE_2123607
uniprot id: G2RHP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2124464
gene id: 578455:THITE_2124464
uniprot id: G2RFV3
names: Similarity
messages: Belongs to the WD repeat LST8 family.

578455:THITE 2109168
gene id: 578455:THITE_2109168
uniprot id: G2QTX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

578455:THITE 2106857
gene id: 578455:THITE_2106857
uniprot id: G2QRW3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

578455:THITE 125061
gene id: 578455:THITE_125061
uniprot id: G2R8Q2
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

578455:THITE 2123051
gene id: 578455:THITE_2123051
uniprot id: G2RGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

578455:THITE 2119876
gene id: 578455:THITE_2119876
uniprot id: G2R900
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

578455:THITE 2092846
gene id: 578455:THITE_2092846
uniprot id: G2RHM6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.

578455:THITE 2112761
gene id: 578455:THITE_2112761
uniprot id: G2R0E6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

578455:THITE 122938
gene id: 578455:THITE_122938
uniprot id: G2REU4
names: Similarity
messages: Belongs to the BolA/IbaG family.

578455:THITE 2118029
gene id: 578455:THITE_2118029
uniprot id: G2R6J8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

578455:THITE 121516
gene id: 578455:THITE_121516
uniprot id: G2R9S0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118076
gene id: 578455:THITE_2118076
uniprot id: G2R6V7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2118136
gene id: 578455:THITE_2118136
uniprot id: G2R744
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2113433
gene id: 578455:THITE_2113433
uniprot id: G2R2V5
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2047729
gene id: 578455:THITE_2047729
uniprot id: G2QZR1
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

578455:THITE 2106287
gene id: 578455:THITE_2106287
uniprot id: G2QX62
names: Similarity
messages: Belongs to the sorting nexin family.

578455:THITE 2118776
gene id: 578455:THITE_2118776
uniprot id: G2RAV9
names: Similarity
messages: Belongs to the ATG101 family.

578455:THITE 2171447
gene id: 578455:THITE_2171447
uniprot id: G2RE72
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2109487
gene id: 578455:THITE_2109487
uniprot id: G2QWB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

578455:THITE 2115713
gene id: 578455:THITE_2115713
uniprot id: G2R5D8
names: Similarity
messages: Belongs to the VPS52 family.

578455:THITE 34523
gene id: 578455:THITE_34523
uniprot id: G2R1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Secreted

578455:THITE 2122643
gene id: 578455:THITE_2122643
uniprot id: G2RDP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2117416
gene id: 578455:THITE_2117416
uniprot id: G2R814
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

578455:THITE 2121633
gene id: 578455:THITE_2121633
uniprot id: G2RF51
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2110656
gene id: 578455:THITE_2110656
uniprot id: G2QU21
names: Similarity
messages: Belongs to the SIP5 family.

578455:THITE 2115397
gene id: 578455:THITE_2115397
uniprot id: G2R4D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

578455:THITE 2109765
gene id: 578455:THITE_2109765
uniprot id: G2QXX9
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

578455:THITE 2117110
gene id: 578455:THITE_2117110
uniprot id: G2R7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.

578455:THITE 2054178
gene id: 578455:THITE_2054178
uniprot id: G2RB83
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107087
gene id: 578455:THITE_2107087
uniprot id: G2QST1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2117581
gene id: 578455:THITE_2117581
uniprot id: G2R8A5
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

578455:THITE 2122761
gene id: 578455:THITE_2122761
uniprot id: G2RE76
names: Similarity
messages: Belongs to the cullin family.

578455:THITE 126432
gene id: 578455:THITE_126432
uniprot id: G2QW39
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

578455:THITE 2112855
gene id: 578455:THITE_2112855
uniprot id: G2R0W9
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

578455:THITE 61961
gene id: 578455:THITE_61961
uniprot id: G2RE59
names: Similarity
messages: Belongs to the FAH family.

578455:THITE 2109223
gene id: 578455:THITE_2109223
uniprot id: G2QUD8
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

578455:THITE 66942
gene id: 578455:THITE_66942
uniprot id: G2R117
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

578455:THITE 2118253
gene id: 578455:THITE_2118253
uniprot id: G2R961
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

578455:THITE 2109698
gene id: 578455:THITE_2109698
uniprot id: G2QXJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24 family.
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

578455:THITE 2110864
gene id: 578455:THITE_2110864
uniprot id: G2QUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2116570
gene id: 578455:THITE_2116570
uniprot id: G2R6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2108249
gene id: 578455:THITE_2108249
uniprot id: G2QQP8
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2044357
gene id: 578455:THITE_2044357
uniprot id: G2QZN7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

578455:THITE 2108999
gene id: 578455:THITE_2108999
uniprot id: G2QT35
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2147393
gene id: 578455:THITE_2147393
uniprot id: G2RCF2
names: Similarity
messages: Belongs to the peptidase S28 family.

578455:THITE 2117985
gene id: 578455:THITE_2117985
uniprot id: G2R6B0
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

578455:THITE 2106817
gene id: 578455:THITE_2106817
uniprot id: G2QRJ3
names: Similarity
messages: Belongs to the ATPase C chain family.

578455:THITE 2017839
gene id: 578455:THITE_2017839
uniprot id: G2R9H8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111856
gene id: 578455:THITE_2111856
uniprot id: G2R3P7
names: Subcellular Location Annotation
messages: Cell membrane

578455:THITE 2115092
gene id: 578455:THITE_2115092
uniprot id: G2R319
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

578455:THITE 2069563
gene id: 578455:THITE_2069563
uniprot id: G2RDU5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

578455:THITE 2106967
gene id: 578455:THITE_2106967
uniprot id: G2QSC4
names: Function
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).

578455:THITE 2110621
gene id: 578455:THITE_2110621
uniprot id: G2QTP4
names: Similarity
messages: Belongs to the UFD1 family.

578455:THITE 2114152
gene id: 578455:THITE_2114152
uniprot id: G2QYA3
names: Similarity
messages: Belongs to the cullin family.

578455:THITE 2122131
gene id: 578455:THITE_2122131
uniprot id: G2RC98
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2128319
gene id: 578455:THITE_2128319
uniprot id: G2QYD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2112897
gene id: 578455:THITE_2112897
uniprot id: G2R0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2112449
gene id: 578455:THITE_2112449
uniprot id: G2QZ19
names: Similarity
messages: Belongs to the CBF/MAK21 family.

578455:THITE 2156744
gene id: 578455:THITE_2156744
uniprot id: G2RI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 165581
gene id: 578455:THITE_165581
uniprot id: G2R8K6
names: Similarity
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.

578455:THITE 2115103
gene id: 578455:THITE_2115103
uniprot id: G2R328
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

578455:THITE 2121199
gene id: 578455:THITE_2121199
uniprot id: G2REM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2121574
gene id: 578455:THITE_2121574
uniprot id: G2RF29
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

578455:THITE 2037149
gene id: 578455:THITE_2037149
uniprot id: G2QXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

578455:THITE 2110789
gene id: 578455:THITE_2110789
uniprot id: G2QUI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

578455:THITE 2117925
gene id: 578455:THITE_2117925
uniprot id: G2R680
names: Similarity
messages: Belongs to the PAL/histidase family.

578455:THITE 2108659
gene id: 578455:THITE_2108659
uniprot id: G2QS32
names: Similarity
messages: Belongs to the LTV1 family.

578455:THITE 2111311
gene id: 578455:THITE_2111311
uniprot id: G2R1U3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

578455:THITE 2110126
gene id: 578455:THITE_2110126
uniprot id: G2QRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution.
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Component of the nuclear pore complex (NPC). NPC constitutes the exclusive means of nucleocytoplasmic transport. NPCs allow the passive diffusion of ions and small molecules and the active, nuclear transport receptor-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and ribosomal subunits across the nuclear envelope. Due to its 8-fold rotational symmetry, all subunits are present with 8 copies or multiples thereof.
messages: nuclear pore complex

578455:THITE 2120262
gene id: 578455:THITE_2120262
uniprot id: G2R9W8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 2156506
gene id: 578455:THITE_2156506
uniprot id: G2RGG2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

578455:THITE 2115330
gene id: 578455:THITE_2115330
uniprot id: G2R406
names: Similarity
messages: Belongs to the CDC73 family.

578455:THITE 2124650
gene id: 578455:THITE_2124650
uniprot id: G2RG67
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

578455:THITE 2116081
gene id: 578455:THITE_2116081
uniprot id: G2QZU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alternative oxidase family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
messages: Mitochondrion inner membrane

578455:THITE 2032902
gene id: 578455:THITE_2032902
uniprot id: G2R7X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex.
messages: trans-Golgi network

578455:THITE 2155551
gene id: 578455:THITE_2155551
uniprot id: G2RB33
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Belongs to the universal ribosomal protein uS10 family.

578455:THITE 2116976
gene id: 578455:THITE_2116976
uniprot id: G2R7D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane
messages: Probable lipid hydrolase.

578455:THITE 2113847
gene id: 578455:THITE_2113847
uniprot id: G2R4A9
names: Similarity
messages: Belongs to the IUNH family.

578455:THITE 2107286
gene id: 578455:THITE_2107286
uniprot id: G2QTD1
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

578455:THITE 2122287
gene id: 578455:THITE_2122287
uniprot id: G2RCQ0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 2171611
gene id: 578455:THITE_2171611
uniprot id: G2RI18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

578455:THITE 2118945
gene id: 578455:THITE_2118945
uniprot id: G2RB35
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family.
messages: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.

578455:THITE 2115865
gene id: 578455:THITE_2115865
uniprot id: G2QYU4
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

578455:THITE 62405
gene id: 578455:THITE_62405
uniprot id: G2QWE3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 53841
gene id: 578455:THITE_53841
uniprot id: G2R612
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2122810
gene id: 578455:THITE_2122810
uniprot id: G2RE95
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

578455:THITE 123924
gene id: 578455:THITE_123924
uniprot id: G2QV06
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2047491
gene id: 578455:THITE_2047491
uniprot id: G2QYF1
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

578455:THITE 2039490
gene id: 578455:THITE_2039490
uniprot id: G2QRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

578455:THITE 2116450
gene id: 578455:THITE_2116450
uniprot id: G2R620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2117616
gene id: 578455:THITE_2117616
uniprot id: G2R8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 2111431
gene id: 578455:THITE_2111431
uniprot id: G2R2B5
names: Similarity
messages: Belongs to the peptidase C19 family.

578455:THITE 2110618
gene id: 578455:THITE_2110618
uniprot id: G2QTP2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122491
gene id: 578455:THITE_2122491
uniprot id: G2RDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

578455:THITE 2123391
gene id: 578455:THITE_2123391
uniprot id: G2RHB0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

578455:THITE 2117303
gene id: 578455:THITE_2117303
uniprot id: G2R7V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

578455:THITE 2110628
gene id: 578455:THITE_2110628
uniprot id: G2QTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2122671
gene id: 578455:THITE_2122671
uniprot id: G2RDX6
names: Similarity
messages: Belongs to the CEF1 family.

578455:THITE 2045470
gene id: 578455:THITE_2045470
uniprot id: G2QZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Secreted

578455:THITE 113354
gene id: 578455:THITE_113354
uniprot id: G2R8U4
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2110309
gene id: 578455:THITE_2110309
uniprot id: G2QSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2112367
gene id: 578455:THITE_2112367
uniprot id: G2QYM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

578455:THITE 2112692
gene id: 578455:THITE_2112692
uniprot id: G2R005
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLT11 family.
messages: Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA.
messages: Nucleus

578455:THITE 2111246
gene id: 578455:THITE_2111246
uniprot id: G2R1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2155971
gene id: 578455:THITE_2155971
uniprot id: G2RDF1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

578455:THITE 2110051
gene id: 578455:THITE_2110051
uniprot id: G2QRD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

578455:THITE 2038523
gene id: 578455:THITE_2038523
uniprot id: G2QXD6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2117442
gene id: 578455:THITE_2117442
uniprot id: G2R825
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2123815
gene id: 578455:THITE_2123815
uniprot id: G2RHY9
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

578455:THITE 2122084
gene id: 578455:THITE_2122084
uniprot id: G2RFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

578455:THITE 2117561
gene id: 578455:THITE_2117561
uniprot id: G2R888
names: Similarity
messages: Belongs to the pyruvate kinase family.

578455:THITE 2115651
gene id: 578455:THITE_2115651
uniprot id: G2R5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

578455:THITE 2113982
gene id: 578455:THITE_2113982
uniprot id: G2R544
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112614
gene id: 578455:THITE_2112614
uniprot id: G2QZK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

578455:THITE 2171499
gene id: 578455:THITE_2171499
uniprot id: G2RGR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 126245
gene id: 578455:THITE_126245
uniprot id: G2QYK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle. Interacts with NOP7 and RRP1. Interacts with RSA4 (via WD repeats).
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

578455:THITE 52349
gene id: 578455:THITE_52349
uniprot id: G2R6V3
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: extracellular space

578455:THITE 2091827
gene id: 578455:THITE_2091827
uniprot id: G2RF46
names: Similarity
messages: Belongs to the palC family.

578455:THITE 119824
gene id: 578455:THITE_119824
uniprot id: G2R513
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

578455:THITE 2123952
gene id: 578455:THITE_2123952
uniprot id: G2RI44
names: Similarity
messages: Belongs to the EME1/MMS4 family.

578455:THITE 2031145
gene id: 578455:THITE_2031145
uniprot id: G2QZD6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

578455:THITE 2121337
gene id: 578455:THITE_2121337
uniprot id: G2RET6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 43789
gene id: 578455:THITE_43789
uniprot id: G2R9Z8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

578455:THITE 2123849
gene id: 578455:THITE_2123849
uniprot id: G2RI03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

578455:THITE 2114523
gene id: 578455:THITE_2114523
uniprot id: G2R051
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

578455:THITE 2143312
gene id: 578455:THITE_2143312
uniprot id: G2R0G4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 42538
gene id: 578455:THITE_42538
uniprot id: G2RAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

578455:THITE 2106900
gene id: 578455:THITE_2106900
uniprot id: G2QRY9
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

578455:THITE 2118900
gene id: 578455:THITE_2118900
uniprot id: G2RB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2108732
gene id: 578455:THITE_2108732
uniprot id: G2QS62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

578455:THITE 2122999
gene id: 578455:THITE_2122999
uniprot id: G2RGF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

578455:THITE 2119108
gene id: 578455:THITE_2119108
uniprot id: G2RBC3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 122564
gene id: 578455:THITE_122564
uniprot id: G2RCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

578455:THITE 2121218
gene id: 578455:THITE_2121218
uniprot id: G2REN8
names: Similarity
messages: Belongs to the TMCO4 family.

578455:THITE 2116687
gene id: 578455:THITE_2116687
uniprot id: G2R700
names: Similarity
messages: Belongs to the VAC14 family.

578455:THITE 2120267
gene id: 578455:THITE_2120267
uniprot id: G2R9X3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

578455:THITE 2077977
gene id: 578455:THITE_2077977
uniprot id: G2R055
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

578455:THITE 2117784
gene id: 578455:THITE_2117784
uniprot id: G2R5M6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107967
gene id: 578455:THITE_2107967
uniprot id: G2QWT6
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

578455:THITE 2108218
gene id: 578455:THITE_2108218
uniprot id: G2QQN7
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

578455:THITE 2107259
gene id: 578455:THITE_2107259
uniprot id: G2QTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

578455:THITE 2109907
gene id: 578455:THITE_2109907
uniprot id: G2QQV0
names: Similarity
messages: Belongs to the VPS25 family.

578455:THITE 2119832
gene id: 578455:THITE_2119832
uniprot id: G2R8Y1
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

578455:THITE 2112864
gene id: 578455:THITE_2112864
uniprot id: G2R0X2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

578455:THITE 2113448
gene id: 578455:THITE_2113448
uniprot id: G2R2W2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 136351
gene id: 578455:THITE_136351
uniprot id: G2R8S1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

578455:THITE 2106058
gene id: 578455:THITE_2106058
uniprot id: G2QW08
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2110570
gene id: 578455:THITE_2110570
uniprot id: G2QTL0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2090704
gene id: 578455:THITE_2090704
uniprot id: G2RBM7
names: Similarity
messages: Belongs to the UPF0045 family.

578455:THITE 2125664
gene id: 578455:THITE_2125664
uniprot id: G2QWT8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

578455:THITE 2050870
gene id: 578455:THITE_2050870
uniprot id: G2R747
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

578455:THITE 2141973
gene id: 578455:THITE_2141973
uniprot id: G2QXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

578455:THITE 2170468
gene id: 578455:THITE_2170468
uniprot id: G2QYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

578455:THITE 2122931
gene id: 578455:THITE_2122931
uniprot id: G2RGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

578455:THITE 2050501
gene id: 578455:THITE_2050501
uniprot id: G2R5F2
names: Similarity
messages: Belongs to the asaB hydroxylase/desaturase family.

578455:THITE 2118266
gene id: 578455:THITE_2118266
uniprot id: G2R9D1
names: Similarity
messages: Belongs to the TPP enzyme family.

578455:THITE 2119383
gene id: 578455:THITE_2119383
uniprot id: G2RBQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

578455:THITE 2114339
gene id: 578455:THITE_2114339
uniprot id: G2QZ88
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

578455:THITE 2124148
gene id: 578455:THITE_2124148
uniprot id: G2RIC5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118196
gene id: 578455:THITE_2118196
uniprot id: G2R923
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

578455:THITE 2106801
gene id: 578455:THITE_2106801
uniprot id: G2QRI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

578455:THITE 2050890
gene id: 578455:THITE_2050890
uniprot id: G2R7N8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2108608
gene id: 578455:THITE_2108608
uniprot id: G2QS14
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

578455:THITE 2106515
gene id: 578455:THITE_2106515
uniprot id: G2QQI9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

578455:THITE 2155054
gene id: 578455:THITE_2155054
uniprot id: G2R799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

578455:THITE 2140577
gene id: 578455:THITE_2140577
uniprot id: G2QWR1
names: Similarity
messages: Belongs to the oxoprolinase family.

578455:THITE 2120469
gene id: 578455:THITE_2120469
uniprot id: G2RAS1
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 40154
gene id: 578455:THITE_40154
uniprot id: G2QVK0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123579
gene id: 578455:THITE_2123579
uniprot id: G2RHM8
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2109003
gene id: 578455:THITE_2109003
uniprot id: G2QTE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

578455:THITE 2106227
gene id: 578455:THITE_2106227
uniprot id: G2QWP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

578455:THITE 124686
gene id: 578455:THITE_124686
uniprot id: G2RFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRG family.
messages: Nucleus

578455:THITE 2116509
gene id: 578455:THITE_2116509
uniprot id: G2R6F0
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

578455:THITE 2120863
gene id: 578455:THITE_2120863
uniprot id: G2RDU7
names: Similarity
messages: Belongs to the peptidase M28 family.

578455:THITE 2047488
gene id: 578455:THITE_2047488
uniprot id: G2R1Q2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

578455:THITE 2092369
gene id: 578455:THITE_2092369
uniprot id: G2RDY0
names: Similarity
messages: Belongs to the HIT family.

578455:THITE 2048877
gene id: 578455:THITE_2048877
uniprot id: G2R3N8
names: Similarity
messages: Belongs to the RdRP family.

578455:THITE 2091867
gene id: 578455:THITE_2091867
uniprot id: G2RF82
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 60812
gene id: 578455:THITE_60812
uniprot id: G2RE99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2093247
gene id: 578455:THITE_2093247
uniprot id: G2RFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

578455:THITE 2093818
gene id: 578455:THITE_2093818
uniprot id: G2QU66
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

578455:THITE 2109791
gene id: 578455:THITE_2109791
uniprot id: G2QXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

578455:THITE 2040319
gene id: 578455:THITE_2040319
uniprot id: G2QU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 159718
gene id: 578455:THITE_159718
uniprot id: G2RGW8
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: extracellular space

578455:THITE 2119173
gene id: 578455:THITE_2119173
uniprot id: G2RBF6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

578455:THITE 2107989
gene id: 578455:THITE_2107989
uniprot id: G2QWV0
names: Similarity
messages: Belongs to the FAX family.

578455:THITE 2108611
gene id: 578455:THITE_2108611
uniprot id: G2QS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

578455:THITE 42931
gene id: 578455:THITE_42931
uniprot id: G2R9B8
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

578455:THITE 2117683
gene id: 578455:THITE_2117683
uniprot id: G2R8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 32842
gene id: 578455:THITE_32842
uniprot id: G2QZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 124061
gene id: 578455:THITE_124061
uniprot id: G2QX51
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113956
gene id: 578455:THITE_2113956
uniprot id: G2R4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

578455:THITE 2121856
gene id: 578455:THITE_2121856
uniprot id: G2RFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

578455:THITE 2114637
gene id: 578455:THITE_2114637
uniprot id: G2R110
names: Similarity
messages: Belongs to the guanylate kinase family.

578455:THITE 2124178
gene id: 578455:THITE_2124178
uniprot id: G2RID3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.

578455:THITE 2124696
gene id: 578455:THITE_2124696
uniprot id: G2RGA6
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

578455:THITE 2044434
gene id: 578455:THITE_2044434
uniprot id: G2QZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

578455:THITE 2147717
gene id: 578455:THITE_2147717
uniprot id: G2RGB9
names: Similarity
messages: Belongs to the RdRP family.

578455:THITE 2114059
gene id: 578455:THITE_2114059
uniprot id: G2R578
names: Similarity
messages: Belongs to the TEL2 family.

578455:THITE 2114222
gene id: 578455:THITE_2114222
uniprot id: G2QYR2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116168
gene id: 578455:THITE_2116168
uniprot id: G2R097
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

578455:THITE 2109625
gene id: 578455:THITE_2109625
uniprot id: G2QX22
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

578455:THITE 2112505
gene id: 578455:THITE_2112505
uniprot id: G2QZ40
names: Similarity
messages: Belongs to the type-1 OGG1 family.

578455:THITE 2142028
gene id: 578455:THITE_2142028
uniprot id: G2QY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

578455:THITE 2115711
gene id: 578455:THITE_2115711
uniprot id: G2R5D7
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

578455:THITE 60465
gene id: 578455:THITE_60465
uniprot id: G2R9J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

578455:THITE 2121000
gene id: 578455:THITE_2121000
uniprot id: G2RE53
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

578455:THITE 2122543
gene id: 578455:THITE_2122543
uniprot id: G2RDE3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2108310
gene id: 578455:THITE_2108310
uniprot id: G2QQR9
names: Similarity
messages: Belongs to the HUS1 family.

578455:THITE 75432
gene id: 578455:THITE_75432
uniprot id: G2RHX6
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

578455:THITE 2116187
gene id: 578455:THITE_2116187
uniprot id: G2R0C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

578455:THITE 2106907
gene id: 578455:THITE_2106907
uniprot id: G2QRZ2
names: Function
names: Similarity
messages: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides.
messages: Belongs to the peptidase M16 family. PreP subfamily.

578455:THITE 2119146
gene id: 578455:THITE_2119146
uniprot id: G2RBE6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2156116
gene id: 578455:THITE_2156116
uniprot id: G2RET5
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

578455:THITE 74156
gene id: 578455:THITE_74156
uniprot id: G2QQY5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106686
gene id: 578455:THITE_2106686
uniprot id: G2QR25
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2109372
gene id: 578455:THITE_2109372
uniprot id: G2QUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

578455:THITE 2118961
gene id: 578455:THITE_2118961
uniprot id: G2RB42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

578455:THITE 48486
gene id: 578455:THITE_48486
uniprot id: G2QVE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

578455:THITE 2113178
gene id: 578455:THITE_2113178
uniprot id: G2R1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

578455:THITE 2120301
gene id: 578455:THITE_2120301
uniprot id: G2RA46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

578455:THITE 2108388
gene id: 578455:THITE_2108388
uniprot id: G2QR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

578455:THITE 2121352
gene id: 578455:THITE_2121352
uniprot id: G2REU1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

578455:THITE 2046475
gene id: 578455:THITE_2046475
uniprot id: G2QZB2
names: Similarity
messages: Belongs to the adenylate kinase family.

578455:THITE 70593
gene id: 578455:THITE_70593
uniprot id: G2QSJ9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2115438
gene id: 578455:THITE_2115438
uniprot id: G2R4F2
names: Similarity
messages: Belongs to the lysophospholipase family.

578455:THITE 2116519
gene id: 578455:THITE_2116519
uniprot id: G2R6F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

578455:THITE 37801
gene id: 578455:THITE_37801
uniprot id: G2R4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

578455:THITE 2114671
gene id: 578455:THITE_2114671
uniprot id: G2R133
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Mitochondrion

578455:THITE 2119816
gene id: 578455:THITE_2119816
uniprot id: G2R8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

578455:THITE 2117524
gene id: 578455:THITE_2117524
uniprot id: G2R872
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NMT1/THI5 family.
messages: Homodimer.
messages: Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.

578455:THITE 2107018
gene id: 578455:THITE_2107018
uniprot id: G2QSE8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

578455:THITE 2111231
gene id: 578455:THITE_2111231
uniprot id: G2R1E2
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

578455:THITE 2116958
gene id: 578455:THITE_2116958
uniprot id: G2R7D1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2130131
gene id: 578455:THITE_2130131
uniprot id: G2R5Z4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2124795
gene id: 578455:THITE_2124795
uniprot id: G2RGS5
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

578455:THITE 2116023
gene id: 578455:THITE_2116023
uniprot id: G2QZF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2.
messages: nucleolus

578455:THITE 2119994
gene id: 578455:THITE_2119994
uniprot id: G2R9B4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107413
gene id: 578455:THITE_2107413
uniprot id: G2QTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

578455:THITE 2117215
gene id: 578455:THITE_2117215
uniprot id: G2R7R9
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

578455:THITE 30409
gene id: 578455:THITE_30409
uniprot id: G2RHB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

578455:THITE 2123424
gene id: 578455:THITE_2123424
uniprot id: G2RHD0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

578455:THITE 2076582
gene id: 578455:THITE_2076582
uniprot id: G2QY53
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2118508
gene id: 578455:THITE_2118508
uniprot id: G2RA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

578455:THITE 2107143
gene id: 578455:THITE_2107143
uniprot id: G2QSW3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

578455:THITE 2121177
gene id: 578455:THITE_2121177
uniprot id: G2REM1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

578455:THITE 33488
gene id: 578455:THITE_33488
uniprot id: G2QYR1
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2115503
gene id: 578455:THITE_2115503
uniprot id: G2R4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

578455:THITE 2106781
gene id: 578455:THITE_2106781
uniprot id: G2QRH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

578455:THITE 2122833
gene id: 578455:THITE_2122833
uniprot id: G2REA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Mitochondrion inner membrane

578455:THITE 2143975
gene id: 578455:THITE_2143975
uniprot id: G2R037
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 75 family.
messages: Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.
messages: Secreted

578455:THITE 2118531
gene id: 578455:THITE_2118531
uniprot id: G2RA90
names: Similarity
messages: Belongs to the RMD1/sif2 family.

578455:THITE 2119239
gene id: 578455:THITE_2119239
uniprot id: G2RBI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

578455:THITE 2147182
gene id: 578455:THITE_2147182
uniprot id: G2RF58
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2108345
gene id: 578455:THITE_2108345
uniprot id: G2QR46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2107857
gene id: 578455:THITE_2107857
uniprot id: G2QVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2106802
gene id: 578455:THITE_2106802
uniprot id: G2QRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

578455:THITE 2111326
gene id: 578455:THITE_2111326
uniprot id: G2R1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

578455:THITE 2069898
gene id: 578455:THITE_2069898
uniprot id: G2REX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

578455:THITE 2115054
gene id: 578455:THITE_2115054
uniprot id: G2R301
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

578455:THITE 2121755
gene id: 578455:THITE_2121755
uniprot id: G2RF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

578455:THITE 2117730
gene id: 578455:THITE_2117730
uniprot id: G2R8R7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

578455:THITE 2042889
gene id: 578455:THITE_2042889
uniprot id: G2QSA0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115457
gene id: 578455:THITE_2115457
uniprot id: G2R4G3
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

578455:THITE 2109481
gene id: 578455:THITE_2109481
uniprot id: G2QWA9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2113848
gene id: 578455:THITE_2113848
uniprot id: G2R4B0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107542
gene id: 578455:THITE_2107542
uniprot id: G2QU88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

578455:THITE 2116758
gene id: 578455:THITE_2116758
uniprot id: G2R725
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

578455:THITE 155482
gene id: 578455:THITE_155482
uniprot id: G2RAA2
names: Similarity
messages: Belongs to the CAF1 family.

578455:THITE 2147221
gene id: 578455:THITE_2147221
uniprot id: G2RFA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

578455:THITE 2113588
gene id: 578455:THITE_2113588
uniprot id: G2R3C9
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

578455:THITE 2123435
gene id: 578455:THITE_2123435
uniprot id: G2RHD5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

578455:THITE 2056235
gene id: 578455:THITE_2056235
uniprot id: G2RCD5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109869
gene id: 578455:THITE_2109869
uniprot id: G2QQT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2124721
gene id: 578455:THITE_2124721
uniprot id: G2RGH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

578455:THITE 2109134
gene id: 578455:THITE_2109134
uniprot id: G2QTW0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

578455:THITE 2107832
gene id: 578455:THITE_2107832
uniprot id: G2QVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

578455:THITE 2118014
gene id: 578455:THITE_2118014
uniprot id: G2R6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

578455:THITE 2121580
gene id: 578455:THITE_2121580
uniprot id: G2RF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2068211
gene id: 578455:THITE_2068211
uniprot id: G2RAX0
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

578455:THITE 60693
gene id: 578455:THITE_60693
uniprot id: G2RAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

578455:THITE 2142551
gene id: 578455:THITE_2142551
uniprot id: G2QVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

578455:THITE 2119211
gene id: 578455:THITE_2119211
uniprot id: G2RBH0
names: Similarity
messages: Belongs to the HEATR5 family.

578455:THITE 2107105
gene id: 578455:THITE_2107105
uniprot id: G2QSU1
names: Similarity
messages: Belongs to the peroxidase family.

578455:THITE 2111218
gene id: 578455:THITE_2111218
uniprot id: G2R1D1
names: Similarity
messages: Belongs to the NipSnap family.

578455:THITE 2120596
gene id: 578455:THITE_2120596
uniprot id: G2RCT9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

578455:THITE 2076439
gene id: 578455:THITE_2076439
uniprot id: G2R4H9
names: Similarity
messages: Belongs to the peptidase S8 family.

578455:THITE 163734
gene id: 578455:THITE_163734
uniprot id: G2RCR4
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

578455:THITE 2123271
gene id: 578455:THITE_2123271
uniprot id: G2RH49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

578455:THITE 2120548
gene id: 578455:THITE_2120548
uniprot id: G2RCL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2116739
gene id: 578455:THITE_2116739
uniprot id: G2R718
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

578455:THITE 2109153
gene id: 578455:THITE_2109153
uniprot id: G2QTW7
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2141037
gene id: 578455:THITE_2141037
uniprot id: G2QU63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

578455:THITE 2108049
gene id: 578455:THITE_2108049
uniprot id: G2QXC9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2115107
gene id: 578455:THITE_2115107
uniprot id: G2R331
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

578455:THITE 2114286
gene id: 578455:THITE_2114286
uniprot id: G2QZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

578455:THITE 2113541
gene id: 578455:THITE_2113541
uniprot id: G2R3B1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

578455:THITE 2108747
gene id: 578455:THITE_2108747
uniprot id: G2QSH4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

578455:THITE 2054543
gene id: 578455:THITE_2054543
uniprot id: G2R9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2107772
gene id: 578455:THITE_2107772
uniprot id: G2QV66
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2117221
gene id: 578455:THITE_2117221
uniprot id: G2R7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Chromosome

578455:THITE 2107803
gene id: 578455:THITE_2107803
uniprot id: G2QVJ4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

578455:THITE 2107799
gene id: 578455:THITE_2107799
uniprot id: G2QV82
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

578455:THITE 2120293
gene id: 578455:THITE_2120293
uniprot id: G2RA42
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

578455:THITE 2056559
gene id: 578455:THITE_2056559
uniprot id: G2RFC3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108279
gene id: 578455:THITE_2108279
uniprot id: G2QQQ7
names: Similarity
messages: Belongs to the aspartokinase family.

578455:THITE 118384
gene id: 578455:THITE_118384
uniprot id: G2QYY9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 34437
gene id: 578455:THITE_34437
uniprot id: G2QYR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pectinesterase family.
messages: Involved in maceration and soft-rotting of plant tissue.
messages: Secreted

578455:THITE 2068692
gene id: 578455:THITE_2068692
uniprot id: G2RBZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2117517
gene id: 578455:THITE_2117517
uniprot id: G2R868
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

578455:THITE 2115805
gene id: 578455:THITE_2115805
uniprot id: G2QYF5
names: Similarity
messages: Belongs to the SAP30 family.

578455:THITE 34477
gene id: 578455:THITE_34477
uniprot id: G2R4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Cytoplasm
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.

578455:THITE 2114824
gene id: 578455:THITE_2114824
uniprot id: G2R233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM54 family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2117672
gene id: 578455:THITE_2117672
uniprot id: G2R8H6
names: Similarity
messages: Belongs to the peptidase M67C family.

578455:THITE 2123706
gene id: 578455:THITE_2123706
uniprot id: G2RHT6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114743
gene id: 578455:THITE_2114743
uniprot id: G2R1N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2124098
gene id: 578455:THITE_2124098
uniprot id: G2RIA3
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

578455:THITE 2065728
gene id: 578455:THITE_2065728
uniprot id: G2R2Y2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

578455:THITE 126248
gene id: 578455:THITE_126248
uniprot id: G2QY80
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

578455:THITE 2145086
gene id: 578455:THITE_2145086
uniprot id: G2R795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 52613
gene id: 578455:THITE_52613
uniprot id: G2R8Q3
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 2123211
gene id: 578455:THITE_2123211
uniprot id: G2RH00
names: Similarity
messages: Belongs to the UPP synthase family.

578455:THITE 2115595
gene id: 578455:THITE_2115595
uniprot id: G2R4Y3
names: Similarity
messages: In the 2nd section; belongs to the type-I 3-dehydroquinase family.
messages: In the N-terminal section; belongs to the shikimate kinase family.

578455:THITE 2107740
gene id: 578455:THITE_2107740
uniprot id: G2QV37
names: Similarity
messages: Belongs to the CAND family.

578455:THITE 2116209
gene id: 578455:THITE_2116209
uniprot id: G2R0R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2115620
gene id: 578455:THITE_2115620
uniprot id: G2R5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM41 family.
messages: Mitochondrion

578455:THITE 2090520
gene id: 578455:THITE_2090520
uniprot id: G2RB36
names: Similarity
messages: Belongs to the FUN14 family.

578455:THITE 2114204
gene id: 578455:THITE_2114204
uniprot id: G2QYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

578455:THITE 2110933
gene id: 578455:THITE_2110933
uniprot id: G2QVG1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118148
gene id: 578455:THITE_2118148
uniprot id: G2R8T7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

578455:THITE 125655
gene id: 578455:THITE_125655
uniprot id: G2R5F1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106862
gene id: 578455:THITE_2106862
uniprot id: G2QRW5
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

578455:THITE 2124711
gene id: 578455:THITE_2124711
uniprot id: G2RGB0
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

578455:THITE 2116070
gene id: 578455:THITE_2116070
uniprot id: G2QZU2
names: Similarity
messages: Belongs to the GroES chaperonin family.

578455:THITE 2112147
gene id: 578455:THITE_2112147
uniprot id: G2R520
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Mitochondrion inner membrane

578455:THITE 2118035
gene id: 578455:THITE_2118035
uniprot id: G2R6K5
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

578455:THITE 2111896
gene id: 578455:THITE_2111896
uniprot id: G2R425
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

578455:THITE 2108187
gene id: 578455:THITE_2108187
uniprot id: G2QXW4
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2109457
gene id: 578455:THITE_2109457
uniprot id: G2QVT3
names: Similarity
messages: Belongs to the Luc7 family.

578455:THITE 2106750
gene id: 578455:THITE_2106750
uniprot id: G2QRG9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

578455:THITE 2051579
gene id: 578455:THITE_2051579
uniprot id: G2R767
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2059628
gene id: 578455:THITE_2059628
uniprot id: G2RG57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

578455:THITE 2122379
gene id: 578455:THITE_2122379
uniprot id: G2RD02
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2123443
gene id: 578455:THITE_2123443
uniprot id: G2RHE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

578455:THITE 2117335
gene id: 578455:THITE_2117335
uniprot id: G2R7X6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

578455:THITE 2118343
gene id: 578455:THITE_2118343
uniprot id: G2R9P8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116206
gene id: 578455:THITE_2116206
uniprot id: G2R0R0
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

578455:THITE 2046078
gene id: 578455:THITE_2046078
uniprot id: G2R4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

578455:THITE 2119245
gene id: 578455:THITE_2119245
uniprot id: G2RBI6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

578455:THITE 129744
gene id: 578455:THITE_129744
uniprot id: G2QUS1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

578455:THITE 40647
gene id: 578455:THITE_40647
uniprot id: G2QT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

578455:THITE 2111925
gene id: 578455:THITE_2111925
uniprot id: G2R438
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 2149193
gene id: 578455:THITE_2149193
uniprot id: G2QTW8
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

578455:THITE 2121549
gene id: 578455:THITE_2121549
uniprot id: G2RF20
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

578455:THITE 2106408
gene id: 578455:THITE_2106408
uniprot id: G2QXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

578455:THITE 2170642
gene id: 578455:THITE_2170642
uniprot id: G2R7P9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2121990
gene id: 578455:THITE_2121990
uniprot id: G2RFK1
names: Function
names: Similarity
messages: Belongs to the NARF family.
messages: Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins.

578455:THITE 2122453
gene id: 578455:THITE_2122453
uniprot id: G2RDA2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

578455:THITE 2119784
gene id: 578455:THITE_2119784
uniprot id: G2R8W1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

578455:THITE 2062148
gene id: 578455:THITE_2062148
uniprot id: G2QU95
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

578455:THITE 2113973
gene id: 578455:THITE_2113973
uniprot id: G2R4T2
names: Similarity
messages: Belongs to the serine esterase family.

578455:THITE 2117788
gene id: 578455:THITE_2117788
uniprot id: G2R5M7
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

578455:THITE 2132051
gene id: 578455:THITE_2132051
uniprot id: G2RCF8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 49799
gene id: 578455:THITE_49799
uniprot id: G2RGS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Gfa family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.

578455:THITE 2047471
gene id: 578455:THITE_2047471
uniprot id: G2R2J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

578455:THITE 135466
gene id: 578455:THITE_135466
uniprot id: G2QXG9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2108018
gene id: 578455:THITE_2108018
uniprot id: G2QWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

578455:THITE 2141914
gene id: 578455:THITE_2141914
uniprot id: G2QWF6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106224
gene id: 578455:THITE_2106224
uniprot id: G2QWP5
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

578455:THITE 2109129
gene id: 578455:THITE_2109129
uniprot id: G2QTV9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 135180
gene id: 578455:THITE_135180
uniprot id: G2REX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

578455:THITE 2114279
gene id: 578455:THITE_2114279
uniprot id: G2QZ50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2142112
gene id: 578455:THITE_2142112
uniprot id: G2QRA9
names: Similarity
messages: Belongs to the peptidase M24B family.

578455:THITE 2117382
gene id: 578455:THITE_2117382
uniprot id: G2R7Z8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

578455:THITE 53748
gene id: 578455:THITE_53748
uniprot id: G2R5J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 65985
gene id: 578455:THITE_65985
uniprot id: G2R0S9
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2109629
gene id: 578455:THITE_2109629
uniprot id: G2QXG5
names: Similarity
messages: Belongs to the SEC3 family.

578455:THITE 2109327
gene id: 578455:THITE_2109327
uniprot id: G2RH16
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2107805
gene id: 578455:THITE_2107805
uniprot id: G2QVJ6
names: Similarity
messages: Belongs to the COG2 family.

578455:THITE 2117540
gene id: 578455:THITE_2117540
uniprot id: G2R881
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

578455:THITE 2117772
gene id: 578455:THITE_2117772
uniprot id: G2R5L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

578455:THITE 15861
gene id: 578455:THITE_15861
uniprot id: G2R4R1
names: Similarity
messages: Belongs to the peptidase C15 family.

578455:THITE 2123114
gene id: 578455:THITE_2123114
uniprot id: G2RGQ7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

578455:THITE 2108988
gene id: 578455:THITE_2108988
uniprot id: G2QT30
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122885
gene id: 578455:THITE_2122885
uniprot id: G2REJ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2108832
gene id: 578455:THITE_2108832
uniprot id: G2QSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

578455:THITE 2119314
gene id: 578455:THITE_2119314
uniprot id: G2RBL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2132391
gene id: 578455:THITE_2132391
uniprot id: G2RG55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

578455:THITE 2156580
gene id: 578455:THITE_2156580
uniprot id: G2RH57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

578455:THITE 2110305
gene id: 578455:THITE_2110305
uniprot id: G2QSB1
names: Similarity
messages: Belongs to the epsin family.

578455:THITE 2109567
gene id: 578455:THITE_2109567
uniprot id: G2QWZ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2116766
gene id: 578455:THITE_2116766
uniprot id: G2R728
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

578455:THITE 160963
gene id: 578455:THITE_160963
uniprot id: G2R8J4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2121135
gene id: 578455:THITE_2121135
uniprot id: G2REG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anthrone oxygenase family.
messages: Membrane

578455:THITE 2120371
gene id: 578455:THITE_2120371
uniprot id: G2RAE5
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

578455:THITE 2112991
gene id: 578455:THITE_2112991
uniprot id: G2R1H3
names: Similarity
messages: Belongs to the PP2C family.

578455:THITE 2154828
gene id: 578455:THITE_2154828
uniprot id: G2QYW8
names: Function
names: Similarity
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.

578455:THITE 2120449
gene id: 578455:THITE_2120449
uniprot id: G2RAQ1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

578455:THITE 2117480
gene id: 578455:THITE_2117480
uniprot id: G2R842
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

578455:THITE 2075857
gene id: 578455:THITE_2075857
uniprot id: G2QYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2117961
gene id: 578455:THITE_2117961
uniprot id: G2R695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

578455:THITE 2107543
gene id: 578455:THITE_2107543
uniprot id: G2QU89
names: Similarity
messages: Belongs to the SMAP family.

578455:THITE 2048148
gene id: 578455:THITE_2048148
uniprot id: G2R4M6
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2119790
gene id: 578455:THITE_2119790
uniprot id: G2R8W4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

578455:THITE 2040656
gene id: 578455:THITE_2040656
uniprot id: G2QUD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ODC antizyme family.
messages: Interacts with ODC and thereby sterically blocks ODC homodimerization.
messages: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.

578455:THITE 2122180
gene id: 578455:THITE_2122180
uniprot id: G2RCC6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2044375
gene id: 578455:THITE_2044375
uniprot id: G2R3M0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2113531
gene id: 578455:THITE_2113531
uniprot id: G2R3A7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111273
gene id: 578455:THITE_2111273
uniprot id: G2R1S1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

578455:THITE 2111114
gene id: 578455:THITE_2111114
uniprot id: G2QWJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

578455:THITE 2120208
gene id: 578455:THITE_2120208
uniprot id: G2R9U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome.
messages: Belongs to the CWF11 family.
messages: Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
messages: Nucleus

578455:THITE 2044206
gene id: 578455:THITE_2044206
uniprot id: G2R4R5
names: Similarity
messages: Belongs to the PGA52 family.

578455:THITE 2045416
gene id: 578455:THITE_2045416
uniprot id: G2R0M4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

578455:THITE 2108787
gene id: 578455:THITE_2108787
uniprot id: G2QSI8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 2109664
gene id: 578455:THITE_2109664
uniprot id: G2QXI1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

578455:THITE 2170929
gene id: 578455:THITE_2170929
uniprot id: G2RBH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

578455:THITE 2122032
gene id: 578455:THITE_2122032
uniprot id: G2RFL8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

578455:THITE 2039441
gene id: 578455:THITE_2039441
uniprot id: G2QT26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
messages: Cytoplasm
messages: Homodimer.

578455:THITE 2121449
gene id: 578455:THITE_2121449
uniprot id: G2REX4
names: Function
names: Similarity
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.

578455:THITE 2122505
gene id: 578455:THITE_2122505
uniprot id: G2RDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

578455:THITE 2040984
gene id: 578455:THITE_2040984
uniprot id: G2QRB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2113733
gene id: 578455:THITE_2113733
uniprot id: G2R3W0
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

578455:THITE 2109275
gene id: 578455:THITE_2109275
uniprot id: G2QUG8
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2117543
gene id: 578455:THITE_2117543
uniprot id: G2R882
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

578455:THITE 2109933
gene id: 578455:THITE_2109933
uniprot id: G2QQV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

578455:THITE 2108845
gene id: 578455:THITE_2108845
uniprot id: G2QSL3
names: Similarity
messages: Belongs to the IFRD family.

578455:THITE 2122864
gene id: 578455:THITE_2122864
uniprot id: G2REI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

578455:THITE 2054382
gene id: 578455:THITE_2054382
uniprot id: G2R9D6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

578455:THITE 2121815
gene id: 578455:THITE_2121815
uniprot id: G2RFC0
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

578455:THITE 2113845
gene id: 578455:THITE_2113845
uniprot id: G2R4A8
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2120000
gene id: 578455:THITE_2120000
uniprot id: G2R9B5
names: Similarity
messages: Belongs to the NRDE2 family.

578455:THITE 133281
gene id: 578455:THITE_133281
uniprot id: G2QYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

578455:THITE 2117395
gene id: 578455:THITE_2117395
uniprot id: G2R806
names: Similarity
messages: Belongs to the group II decarboxylase family.

578455:THITE 2117028
gene id: 578455:THITE_2117028
uniprot id: G2R7G8
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

578455:THITE 2044172
gene id: 578455:THITE_2044172
uniprot id: G2R3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLASP family.
messages: Interacts with microtubules.
messages: Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation.
messages: spindle

578455:THITE 2107714
gene id: 578455:THITE_2107714
uniprot id: G2QUR5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

578455:THITE 2106847
gene id: 578455:THITE_2106847
uniprot id: G2QRK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2113576
gene id: 578455:THITE_2113576
uniprot id: G2R3C2
names: Cofactor
names: PTM
names: Similarity
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.

578455:THITE 124996
gene id: 578455:THITE_124996
uniprot id: G2R5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 35313
gene id: 578455:THITE_35313
uniprot id: G2QYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

578455:THITE 2121558
gene id: 578455:THITE_2121558
uniprot id: G2RF23
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

578455:THITE 2057765
gene id: 578455:THITE_2057765
uniprot id: G2RCW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

578455:THITE 2107687
gene id: 578455:THITE_2107687
uniprot id: G2QUQ2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

578455:THITE 2114839
gene id: 578455:THITE_2114839
uniprot id: G2R244
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

578455:THITE 34416
gene id: 578455:THITE_34416
uniprot id: G2R5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

578455:THITE 2118644
gene id: 578455:THITE_2118644
uniprot id: G2RAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

578455:THITE 2116411
gene id: 578455:THITE_2116411
uniprot id: G2R5T8
names: Similarity
messages: Belongs to the Gfa family.

578455:THITE 2115051
gene id: 578455:THITE_2115051
uniprot id: G2R300
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

578455:THITE 2116024
gene id: 578455:THITE_2116024
uniprot id: G2QZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 72454
gene id: 578455:THITE_72454
uniprot id: G2RDQ2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

578455:THITE 2037962
gene id: 578455:THITE_2037962
uniprot id: G2QRL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

578455:THITE 2169250
gene id: 578455:THITE_2169250
uniprot id: G2QSV2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

578455:THITE 154420
gene id: 578455:THITE_154420
uniprot id: G2QV44
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2010984
gene id: 578455:THITE_2010984
uniprot id: G2QZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

578455:THITE 2084845
gene id: 578455:THITE_2084845
uniprot id: G2QR75
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

578455:THITE 124883
gene id: 578455:THITE_124883
uniprot id: G2R6U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2114929
gene id: 578455:THITE_2114929
uniprot id: G2R2J1
names: Similarity
messages: Belongs to the TYW1 family.

578455:THITE 2116720
gene id: 578455:THITE_2116720
uniprot id: G2R713
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

578455:THITE 2119386
gene id: 578455:THITE_2119386
uniprot id: G2RBQ6
names: Similarity
messages: Belongs to the MIF family.

578455:THITE 2115240
gene id: 578455:THITE_2115240
uniprot id: G2R3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

578455:THITE 2108460
gene id: 578455:THITE_2108460
uniprot id: G2QRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

578455:THITE 2169538
gene id: 578455:THITE_2169538
uniprot id: G2QUG5
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

578455:THITE 2120623
gene id: 578455:THITE_2120623
uniprot id: G2RCY0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107159
gene id: 578455:THITE_2107159
uniprot id: G2QSX0
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

578455:THITE 2072089
gene id: 578455:THITE_2072089
uniprot id: G2QW51
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117428
gene id: 578455:THITE_2117428
uniprot id: G2R818
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2117332
gene id: 578455:THITE_2117332
uniprot id: G2R7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

578455:THITE 2107970
gene id: 578455:THITE_2107970
uniprot id: G2QWT7
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 67758
gene id: 578455:THITE_67758
uniprot id: G2R2D2
names: Similarity
messages: Belongs to the VPS37 family.

578455:THITE 2119130
gene id: 578455:THITE_2119130
uniprot id: G2RBD4
names: Similarity
messages: Belongs to the peptidase M16 family.

578455:THITE 2144921
gene id: 578455:THITE_2144921
uniprot id: G2R6C0
names: Similarity
messages: Belongs to the peptidase S33 family.

578455:THITE 2094562
gene id: 578455:THITE_2094562
uniprot id: G2QU51
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.

578455:THITE 2120314
gene id: 578455:THITE_2120314
uniprot id: G2RA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 2170138
gene id: 578455:THITE_2170138
uniprot id: G2R2W4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 54138
gene id: 578455:THITE_54138
uniprot id: G2QZA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.

578455:THITE 2119583
gene id: 578455:THITE_2119583
uniprot id: G2RBZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

578455:THITE 2123755
gene id: 578455:THITE_2123755
uniprot id: G2RHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD3 family.
messages: Nucleus
messages: kinetochore
messages: spindle

578455:THITE 2115585
gene id: 578455:THITE_2115585
uniprot id: G2R4X9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2043209
gene id: 578455:THITE_2043209
uniprot id: G2QXF2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116544
gene id: 578455:THITE_2116544
uniprot id: G2R6N9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

578455:THITE 2111295
gene id: 578455:THITE_2111295
uniprot id: G2R1T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

578455:THITE 2109382
gene id: 578455:THITE_2109382
uniprot id: G2QV94
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2110530
gene id: 578455:THITE_2110530
uniprot id: G2QT76
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

578455:THITE 2113850
gene id: 578455:THITE_2113850
uniprot id: G2R4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

578455:THITE 2014962
gene id: 578455:THITE_2014962
uniprot id: G2R7S5
names: Caution
names: Similarity
messages: Belongs to the ATPase C chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2111816
gene id: 578455:THITE_2111816
uniprot id: G2R3N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
messages: Secreted

578455:THITE 2114670
gene id: 578455:THITE_2114670
uniprot id: G2R132
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrial mRNA stabilization factor.
messages: Mitochondrion inner membrane
messages: Probable mitochondrial mRNA stabilization factor.

578455:THITE 2123893
gene id: 578455:THITE_2123893
uniprot id: G2RI19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

578455:THITE 2111558
gene id: 578455:THITE_2111558
uniprot id: G2R2S3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

578455:THITE 2108788
gene id: 578455:THITE_2108788
uniprot id: G2QSI9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2111183
gene id: 578455:THITE_2111183
uniprot id: G2R1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

578455:THITE 2119407
gene id: 578455:THITE_2119407
uniprot id: G2RBR5
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family.
messages: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.

578455:THITE 2109401
gene id: 578455:THITE_2109401
uniprot id: G2QVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Membrane

578455:THITE 2106879
gene id: 578455:THITE_2106879
uniprot id: G2QRX9
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

578455:THITE 2116774
gene id: 578455:THITE_2116774
uniprot id: G2R731
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

578455:THITE 2081698
gene id: 578455:THITE_2081698
uniprot id: G2RF55
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107161
gene id: 578455:THITE_2107161
uniprot id: G2QSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

578455:THITE 2123540
gene id: 578455:THITE_2123540
uniprot id: G2RHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

578455:THITE 2096633
gene id: 578455:THITE_2096633
uniprot id: G2RBP4
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

578455:THITE 2118090
gene id: 578455:THITE_2118090
uniprot id: G2R6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2119827
gene id: 578455:THITE_2119827
uniprot id: G2R8X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2118237
gene id: 578455:THITE_2118237
uniprot id: G2R952
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

578455:THITE 2169619
gene id: 578455:THITE_2169619
uniprot id: G2QRA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

578455:THITE 121986
gene id: 578455:THITE_121986
uniprot id: G2RC20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM8 and 3 copies of TIM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

578455:THITE 47394
gene id: 578455:THITE_47394
uniprot id: G2QWI7
names: Similarity
messages: Belongs to the peptidase S8 family.

578455:THITE 2109571
gene id: 578455:THITE_2109571
uniprot id: G2QWZ2
names: Similarity
messages: Belongs to the cyclin family.

578455:THITE 2109162
gene id: 578455:THITE_2109162
uniprot id: G2QTX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2108355
gene id: 578455:THITE_2108355
uniprot id: G2QR50
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

578455:THITE 2118100
gene id: 578455:THITE_2118100
uniprot id: G2R6X2
names: Similarity
messages: Belongs to the IlvD/Edd family.

578455:THITE 2119942
gene id: 578455:THITE_2119942
uniprot id: G2R981
names: Similarity
messages: Belongs to the PAF1 family.

578455:THITE 2110831
gene id: 578455:THITE_2110831
uniprot id: G2QUK6
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

578455:THITE 74701
gene id: 578455:THITE_74701
uniprot id: G2QUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

578455:THITE 127436
gene id: 578455:THITE_127436
uniprot id: G2REM2
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

578455:THITE 59724
gene id: 578455:THITE_59724
uniprot id: G2RB43
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2052945
gene id: 578455:THITE_2052945
uniprot id: G2R9K6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

578455:THITE 2119900
gene id: 578455:THITE_2119900
uniprot id: G2R964
names: Similarity
messages: Belongs to the VPS72/YL1 family.

578455:THITE 2111136
gene id: 578455:THITE_2111136
uniprot id: G2QWL4
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2107310
gene id: 578455:THITE_2107310
uniprot id: G2QTE1
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2110922
gene id: 578455:THITE_2110922
uniprot id: G2QVE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

578455:THITE 2115823
gene id: 578455:THITE_2115823
uniprot id: G2QYG4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

578455:THITE 2117812
gene id: 578455:THITE_2117812
uniprot id: G2R5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

578455:THITE 2144859
gene id: 578455:THITE_2144859
uniprot id: G2R5S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

578455:THITE 2120214
gene id: 578455:THITE_2120214
uniprot id: G2R9U3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

578455:THITE 2144300
gene id: 578455:THITE_2144300
uniprot id: G2R3J5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109545
gene id: 578455:THITE_2109545
uniprot id: G2QWF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

578455:THITE 2119342
gene id: 578455:THITE_2119342
uniprot id: G2RBN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for an H2A variant leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

578455:THITE 125477
gene id: 578455:THITE_125477
uniprot id: G2R6Z5
names: Similarity
messages: Belongs to the peptidase C14B family.

578455:THITE 2119671
gene id: 578455:THITE_2119671
uniprot id: G2RC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

578455:THITE 2118392
gene id: 578455:THITE_2118392
uniprot id: G2R9Y6
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

578455:THITE 2116910
gene id: 578455:THITE_2116910
uniprot id: G2R7A2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2143224
gene id: 578455:THITE_2143224
uniprot id: G2QZI9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2169767
gene id: 578455:THITE_2169767
uniprot id: G2QWH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2114872
gene id: 578455:THITE_2114872
uniprot id: G2R261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2038876
gene id: 578455:THITE_2038876
uniprot id: G2QX58
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2114571
gene id: 578455:THITE_2114571
uniprot id: G2R0J5
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

578455:THITE 2117891
gene id: 578455:THITE_2117891
uniprot id: G2R603
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112909
gene id: 578455:THITE_2112909
uniprot id: G2R0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

578455:THITE 2170949
gene id: 578455:THITE_2170949
uniprot id: G2RBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm

578455:THITE 2054846
gene id: 578455:THITE_2054846
uniprot id: G2RBL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

578455:THITE 2111424
gene id: 578455:THITE_2111424
uniprot id: G2R2B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Prevacuolar compartment membrane
messages: Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).

578455:THITE 2110152
gene id: 578455:THITE_2110152
uniprot id: G2QRT3
names: Similarity
messages: Belongs to the hexokinase family.

578455:THITE 2076671
gene id: 578455:THITE_2076671
uniprot id: G2QYN0
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

578455:THITE 2118143
gene id: 578455:THITE_2118143
uniprot id: G2R752
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116724
gene id: 578455:THITE_2116724
uniprot id: G2R715
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

578455:THITE 135005
gene id: 578455:THITE_135005
uniprot id: G2RCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2121894
gene id: 578455:THITE_2121894
uniprot id: G2RFF8
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

578455:THITE 2096060
gene id: 578455:THITE_2096060
uniprot id: G2R7I9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 2107332
gene id: 578455:THITE_2107332
uniprot id: G2QTQ8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2124287
gene id: 578455:THITE_2124287
uniprot id: G2RIH0
names: Similarity
messages: Belongs to the RRP12 family.

578455:THITE 122601
gene id: 578455:THITE_122601
uniprot id: G2RCP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

578455:THITE 2050866
gene id: 578455:THITE_2050866
uniprot id: G2R5S9
names: Similarity
messages: Belongs to the RNase T2 family.

578455:THITE 2058340
gene id: 578455:THITE_2058340
uniprot id: G2RFX7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

578455:THITE 2116645
gene id: 578455:THITE_2116645
uniprot id: G2R6Y5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

578455:THITE 42761
gene id: 578455:THITE_42761
uniprot id: G2RBB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2114269
gene id: 578455:THITE_2114269
uniprot id: G2QYU0
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2122098
gene id: 578455:THITE_2122098
uniprot id: G2RFN5
names: Similarity
messages: Belongs to the actin family.

578455:THITE 2120808
gene id: 578455:THITE_2120808
uniprot id: G2RDS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small Tim family.
messages: Mitochondrion inner membrane

578455:THITE 2153770
gene id: 578455:THITE_2153770
uniprot id: G2R1V6
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2112286
gene id: 578455:THITE_2112286
uniprot id: G2QY74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

578455:THITE 2109996
gene id: 578455:THITE_2109996
uniprot id: G2QR96
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113863
gene id: 578455:THITE_2113863
uniprot id: G2R4B9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2119335
gene id: 578455:THITE_2119335
uniprot id: G2RBM8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117913
gene id: 578455:THITE_2117913
uniprot id: G2R676
names: Similarity
messages: Belongs to the SAPS family.

578455:THITE 2110696
gene id: 578455:THITE_2110696
uniprot id: G2QU46
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 113895
gene id: 578455:THITE_113895
uniprot id: G2RBN8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2107935
gene id: 578455:THITE_2107935
uniprot id: G2QWA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2114422
gene id: 578455:THITE_2114422
uniprot id: G2QZN4
names: Similarity
messages: Belongs to the MAD1 family.

578455:THITE 42718
gene id: 578455:THITE_42718
uniprot id: G2RBR8
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2077826
gene id: 578455:THITE_2077826
uniprot id: G2QZ49
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

578455:THITE 2118671
gene id: 578455:THITE_2118671
uniprot id: G2RAK9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114103
gene id: 578455:THITE_2114103
uniprot id: G2QY88
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

578455:THITE 68146
gene id: 578455:THITE_68146
uniprot id: G2QZH7
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

578455:THITE 2115164
gene id: 578455:THITE_2115164
uniprot id: G2R3G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2143588
gene id: 578455:THITE_2143588
uniprot id: G2R3B9
names: Similarity
messages: Belongs to the glycosyl hydrolase 45 (cellulase K) family.

578455:THITE 66261
gene id: 578455:THITE_66261
uniprot id: G2QYE9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2145375
gene id: 578455:THITE_2145375
uniprot id: G2R8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT5 family.
messages: Component of the SPT4-SPT5 complex. Interacts with RNA polymerase II.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

578455:THITE 2116549
gene id: 578455:THITE_2116549
uniprot id: G2R6P8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2106411
gene id: 578455:THITE_2106411
uniprot id: G2QXM2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2116923
gene id: 578455:THITE_2116923
uniprot id: G2R7B0
names: Similarity
messages: Belongs to the peptidase S8 family.

578455:THITE 2112880
gene id: 578455:THITE_2112880
uniprot id: G2R0Y0
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

578455:THITE 2122457
gene id: 578455:THITE_2122457
uniprot id: G2RDA3
names: Similarity
messages: Belongs to the fungal fatty acid synthetase subunit beta family.

578455:THITE 2073202
gene id: 578455:THITE_2073202
uniprot id: G2QQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

578455:THITE 2095073
gene id: 578455:THITE_2095073
uniprot id: G2R0V9
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

578455:THITE 2038450
gene id: 578455:THITE_2038450
uniprot id: G2QX24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2122510
gene id: 578455:THITE_2122510
uniprot id: G2RDC9
names: Subunit
messages: Consists of at least two heavy chains and a number of intermediate and light chains.

578455:THITE 2118845
gene id: 578455:THITE_2118845
uniprot id: G2RAY2
names: Similarity
names: Subunit
messages: Belongs to the G-alpha family. G(q) subfamily.
messages: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

578455:THITE 2119136
gene id: 578455:THITE_2119136
uniprot id: G2RBD6
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2118872
gene id: 578455:THITE_2118872
uniprot id: G2RAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

578455:THITE 2110683
gene id: 578455:THITE_2110683
uniprot id: G2QU38
names: Function
names: Similarity
names: Subunit
messages: Associates with DNA double-strand breaks.
messages: Belongs to the PI3/PI4-kinase family.
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.

578455:THITE 2142541
gene id: 578455:THITE_2142541
uniprot id: G2QVX5
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2110323
gene id: 578455:THITE_2110323
uniprot id: G2QSB8
names: Similarity
messages: Belongs to the AATF family.

578455:THITE 2044791
gene id: 578455:THITE_2044791
uniprot id: G2R0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2110960
gene id: 578455:THITE_2110960
uniprot id: G2QVH8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

578455:THITE 2118274
gene id: 578455:THITE_2118274
uniprot id: G2R9E4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

578455:THITE 2150920
gene id: 578455:THITE_2150920
uniprot id: G2R7W3
names: Function
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Polynucleotide 5'-kinase involved in rRNA processing.

578455:THITE 118360
gene id: 578455:THITE_118360
uniprot id: G2QZD9
names: Similarity
messages: Belongs to the glycosyl hydrolase 7 (cellulase C) family.

578455:THITE 2121045
gene id: 578455:THITE_2121045
uniprot id: G2REC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

578455:THITE 2119290
gene id: 578455:THITE_2119290
uniprot id: G2RBK6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2117667
gene id: 578455:THITE_2117667
uniprot id: G2R8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Membrane

578455:THITE 2108082
gene id: 578455:THITE_2108082
uniprot id: G2QXF4
names: Similarity
messages: Belongs to the NAD kinase family.

578455:THITE 2107774
gene id: 578455:THITE_2107774
uniprot id: G2QV67
names: Similarity
messages: Belongs to the SF3A3 family.

578455:THITE 109486
gene id: 578455:THITE_109486
uniprot id: G2RIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

578455:THITE 2106057
gene id: 578455:THITE_2106057
uniprot id: G2QW07
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

578455:THITE 2110543
gene id: 578455:THITE_2110543
uniprot id: G2QT82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

578455:THITE 2121773
gene id: 578455:THITE_2121773
uniprot id: G2RFA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

578455:THITE 2114953
gene id: 578455:THITE_2114953
uniprot id: G2R2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

578455:THITE 2113181
gene id: 578455:THITE_2113181
uniprot id: G2R1Z3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

578455:THITE 2122964
gene id: 578455:THITE_2122964
uniprot id: G2RGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

578455:THITE 2123741
gene id: 578455:THITE_2123741
uniprot id: G2RHV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

578455:THITE 2124541
gene id: 578455:THITE_2124541
uniprot id: G2RFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

578455:THITE 2113679
gene id: 578455:THITE_2113679
uniprot id: G2R3S9
names: Similarity
messages: Belongs to the pyridoxine kinase family.

578455:THITE 2111010
gene id: 578455:THITE_2111010
uniprot id: G2QVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

578455:THITE 2148406
gene id: 578455:THITE_2148406
uniprot id: G2RG65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

578455:THITE 2117141
gene id: 578455:THITE_2117141
uniprot id: G2R7P2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

578455:THITE 2120700
gene id: 578455:THITE_2120700
uniprot id: G2RDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

578455:THITE 2113301
gene id: 578455:THITE_2113301
uniprot id: G2R2E6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

578455:THITE 2123961
gene id: 578455:THITE_2123961
uniprot id: G2RI47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 52693
gene id: 578455:THITE_52693
uniprot id: G2R5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Secreted

578455:THITE 2057681
gene id: 578455:THITE_2057681
uniprot id: G2RD74
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2122533
gene id: 578455:THITE_2122533
uniprot id: G2RDE1
names: Similarity
messages: Belongs to the TTC4 family.

578455:THITE 2114244
gene id: 578455:THITE_2114244
uniprot id: G2QYS6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 39615
gene id: 578455:THITE_39615
uniprot id: G2QXC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Secreted

578455:THITE 2126187
gene id: 578455:THITE_2126187
uniprot id: G2RIC4
names: Similarity
messages: Belongs to the peptidase C48 family.

578455:THITE 2097049
gene id: 578455:THITE_2097049
uniprot id: G2REB7
names: Similarity
messages: Belongs to the peptidase S9C family.

578455:THITE 2122099
gene id: 578455:THITE_2122099
uniprot id: G2RFN6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 108954
gene id: 578455:THITE_108954
uniprot id: G2REF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

578455:THITE 2121059
gene id: 578455:THITE_2121059
uniprot id: G2RED1
names: Similarity
messages: Belongs to the YOS1 family.

578455:THITE 33702
gene id: 578455:THITE_33702
uniprot id: G2R0P9
names: Caution
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2120144
gene id: 578455:THITE_2120144
uniprot id: G2R9L6
names: Similarity
messages: Belongs to the AAR2 family.

578455:THITE 2122075
gene id: 578455:THITE_2122075
uniprot id: G2RFM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

578455:THITE 2112995
gene id: 578455:THITE_2112995
uniprot id: G2R1H5
names: Similarity
messages: Belongs to the TMCO4 family.

578455:THITE 2084928
gene id: 578455:THITE_2084928
uniprot id: G2QS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

578455:THITE 2112800
gene id: 578455:THITE_2112800
uniprot id: G2R0U8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

578455:THITE 2122093
gene id: 578455:THITE_2122093
uniprot id: G2RFN3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2144817
gene id: 578455:THITE_2144817
uniprot id: G2R5H3
names: Similarity
messages: Belongs to the isochorismatase family.

578455:THITE 2106661
gene id: 578455:THITE_2106661
uniprot id: G2QR14
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

578455:THITE 2077915
gene id: 578455:THITE_2077915
uniprot id: G2QZP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.
messages: Mitochondrion matrix

578455:THITE 2080404
gene id: 578455:THITE_2080404
uniprot id: G2RC38
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

578455:THITE 2122753
gene id: 578455:THITE_2122753
uniprot id: G2RE71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

578455:THITE 126270
gene id: 578455:THITE_126270
uniprot id: G2R521
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2119312
gene id: 578455:THITE_2119312
uniprot id: G2RBL5
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

578455:THITE 2112010
gene id: 578455:THITE_2112010
uniprot id: G2R4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

578455:THITE 2079458
gene id: 578455:THITE_2079458
uniprot id: G2R911
names: Similarity
messages: Belongs to the RdRP family.

578455:THITE 2079092
gene id: 578455:THITE_2079092
uniprot id: G2R8D8
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

578455:THITE 2142959
gene id: 578455:THITE_2142959
uniprot id: G2R451
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

578455:THITE 2119862
gene id: 578455:THITE_2119862
uniprot id: G2R8Z5
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

578455:THITE 2111487
gene id: 578455:THITE_2111487
uniprot id: G2R2P3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

578455:THITE 2112714
gene id: 578455:THITE_2112714
uniprot id: G2R014
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

578455:THITE 2084674
gene id: 578455:THITE_2084674
uniprot id: G2QXD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

578455:THITE 2117308
gene id: 578455:THITE_2117308
uniprot id: G2R7V9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106254
gene id: 578455:THITE_2106254
uniprot id: G2QWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.

578455:THITE 2122883
gene id: 578455:THITE_2122883
uniprot id: G2REJ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2118287
gene id: 578455:THITE_2118287
uniprot id: G2R9G9
names: Similarity
messages: Belongs to the MNN1/MNT family.

578455:THITE 2040977
gene id: 578455:THITE_2040977
uniprot id: G2QWM8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 163136
gene id: 578455:THITE_163136
uniprot id: G2RAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

578455:THITE 2110184
gene id: 578455:THITE_2110184
uniprot id: G2QRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

578455:THITE 2082691
gene id: 578455:THITE_2082691
uniprot id: G2RH50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

578455:THITE 2111901
gene id: 578455:THITE_2111901
uniprot id: G2R429
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

578455:THITE 76291
gene id: 578455:THITE_76291
uniprot id: G2R5L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

578455:THITE 2120172
gene id: 578455:THITE_2120172
uniprot id: G2R9M1
names: Similarity
messages: Belongs to the RICTOR family.

578455:THITE 2112429
gene id: 578455:THITE_2112429
uniprot id: G2QZ10
names: Similarity
messages: Belongs to the cullin family.

578455:THITE 2107592
gene id: 578455:THITE_2107592
uniprot id: G2QUB0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2114674
gene id: 578455:THITE_2114674
uniprot id: G2R139
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation.

578455:THITE 2131584
gene id: 578455:THITE_2131584
uniprot id: G2RE45
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2116654
gene id: 578455:THITE_2116654
uniprot id: G2R6Y7
names: Similarity
messages: Belongs to the peptidase C12 family.

578455:THITE 2144773
gene id: 578455:THITE_2144773
uniprot id: G2R1A3
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

578455:THITE 2117251
gene id: 578455:THITE_2117251
uniprot id: G2R7T2
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2070950
gene id: 578455:THITE_2070950
uniprot id: G2RGX9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

578455:THITE 2114616
gene id: 578455:THITE_2114616
uniprot id: G2R0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

578455:THITE 2120142
gene id: 578455:THITE_2120142
uniprot id: G2R9L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

578455:THITE 2170323
gene id: 578455:THITE_2170323
uniprot id: G2R1M8
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

578455:THITE 2113000
gene id: 578455:THITE_2113000
uniprot id: G2R1H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

578455:THITE 2111115
gene id: 578455:THITE_2111115
uniprot id: G2QWK0
names: Similarity
messages: Belongs to the peptidase C19 family.

578455:THITE 2114708
gene id: 578455:THITE_2114708
uniprot id: G2R1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

578455:THITE 2114023
gene id: 578455:THITE_2114023
uniprot id: G2R561
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

578455:THITE 2122404
gene id: 578455:THITE_2122404
uniprot id: G2RD16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2113051
gene id: 578455:THITE_2113051
uniprot id: G2R1J2
names: Similarity
messages: Belongs to the TLS1 family.

578455:THITE 2117106
gene id: 578455:THITE_2117106
uniprot id: G2R7M1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

578455:THITE 2119607
gene id: 578455:THITE_2119607
uniprot id: G2RC10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

578455:THITE 2120258
gene id: 578455:THITE_2120258
uniprot id: G2R9W6
names: Similarity
messages: Belongs to the WD repeat coronin family.

578455:THITE 2040308
gene id: 578455:THITE_2040308
uniprot id: G2QXE1
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

578455:THITE 49687
gene id: 578455:THITE_49687
uniprot id: G2RH01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

578455:THITE 2117243
gene id: 578455:THITE_2117243
uniprot id: G2R7T0
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

578455:THITE 2056637
gene id: 578455:THITE_2056637
uniprot id: G2RCR3
names: Similarity
messages: Belongs to the tyrosinase family.

578455:THITE 2107955
gene id: 578455:THITE_2107955
uniprot id: G2QWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

578455:THITE 2121277
gene id: 578455:THITE_2121277
uniprot id: G2RER1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

578455:THITE 2123410
gene id: 578455:THITE_2123410
uniprot id: G2RHB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

578455:THITE 2107125
gene id: 578455:THITE_2107125
uniprot id: G2QSU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

578455:THITE 2111597
gene id: 578455:THITE_2111597
uniprot id: G2R2T8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

578455:THITE 2108636
gene id: 578455:THITE_2108636
uniprot id: G2QS24
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

578455:THITE 2049009
gene id: 578455:THITE_2049009
uniprot id: G2QYQ9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily.

578455:THITE 2111270
gene id: 578455:THITE_2111270
uniprot id: G2R1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

578455:THITE 76931
gene id: 578455:THITE_76931
uniprot id: G2R705
names: Similarity
messages: Belongs to the CWC22 family.

578455:THITE 121141
gene id: 578455:THITE_121141
uniprot id: G2QRN5
names: Similarity
messages: Belongs to the peptidase S10 family.

578455:THITE 2114712
gene id: 578455:THITE_2114712
uniprot id: G2R1M0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

578455:THITE 108852
gene id: 578455:THITE_108852
uniprot id: G2RF92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

578455:THITE 2123398
gene id: 578455:THITE_2123398
uniprot id: G2RHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

578455:THITE 2109482
gene id: 578455:THITE_2109482
uniprot id: G2QWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2119771
gene id: 578455:THITE_2119771
uniprot id: G2RC81
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 2124813
gene id: 578455:THITE_2124813
uniprot id: G2RGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

578455:THITE 2120978
gene id: 578455:THITE_2120978
uniprot id: G2RE43
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

578455:THITE 2112113
gene id: 578455:THITE_2112113
uniprot id: G2R4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 2118401
gene id: 578455:THITE_2118401
uniprot id: G2R9Y9
names: Similarity
messages: Belongs to the phosducin family.

578455:THITE 121011
gene id: 578455:THITE_121011
uniprot id: G2QXV2
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2120501
gene id: 578455:THITE_2120501
uniprot id: G2RAU6
names: Caution
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 2113186
gene id: 578455:THITE_2113186
uniprot id: G2R1Z5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114850
gene id: 578455:THITE_2114850
uniprot id: G2R249
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

578455:THITE 131994
gene id: 578455:THITE_131994
uniprot id: G2R6W8
names: Similarity
messages: Belongs to the RUS1 family.

578455:THITE 2170173
gene id: 578455:THITE_2170173
uniprot id: G2R3S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

578455:THITE 2111018
gene id: 578455:THITE_2111018
uniprot id: G2QW03
names: Similarity
messages: Belongs to the GCN1 family.

578455:THITE 2111564
gene id: 578455:THITE_2111564
uniprot id: G2R2S7
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).
messages: Belongs to the APS kinase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the sulfate adenylyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.

578455:THITE 2110860
gene id: 578455:THITE_2110860
uniprot id: G2QUM2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

578455:THITE 2110483
gene id: 578455:THITE_2110483
uniprot id: G2QT52
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

578455:THITE 2119261
gene id: 578455:THITE_2119261
uniprot id: G2RBJ3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 68084
gene id: 578455:THITE_68084
uniprot id: G2R006
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of lanosterol to form eburicol.

578455:THITE 2113044
gene id: 578455:THITE_2113044
uniprot id: G2R1J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

578455:THITE 2115342
gene id: 578455:THITE_2115342
uniprot id: G2R411
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2142385
gene id: 578455:THITE_2142385
uniprot id: G2QU16
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2151098
gene id: 578455:THITE_2151098
uniprot id: G2R6V1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 43665
gene id: 578455:THITE_43665
uniprot id: G2RB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2146599
gene id: 578455:THITE_2146599
uniprot id: G2RA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

578455:THITE 2120034
gene id: 578455:THITE_2120034
uniprot id: G2R9I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
messages: Membrane

578455:THITE 2121296
gene id: 578455:THITE_2121296
uniprot id: G2RER9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.

578455:THITE 2117632
gene id: 578455:THITE_2117632
uniprot id: G2R8E8
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2120080
gene id: 578455:THITE_2120080
uniprot id: G2R9J2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

578455:THITE 2118006
gene id: 578455:THITE_2118006
uniprot id: G2R6I1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2110633
gene id: 578455:THITE_2110633
uniprot id: G2QU09
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

578455:THITE 2142624
gene id: 578455:THITE_2142624
uniprot id: G2QX54
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2110901
gene id: 578455:THITE_2110901
uniprot id: G2QV03
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

578455:THITE 2109619
gene id: 578455:THITE_2109619
uniprot id: G2QX20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

578455:THITE 2058099
gene id: 578455:THITE_2058099
uniprot id: G2RG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

578455:THITE 57872
gene id: 578455:THITE_57872
uniprot id: G2QSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

578455:THITE 2106426
gene id: 578455:THITE_2106426
uniprot id: G2QXM7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2106904
gene id: 578455:THITE_2106904
uniprot id: G2QRZ1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

578455:THITE 2117441
gene id: 578455:THITE_2117441
uniprot id: G2R824
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

578455:THITE 2106692
gene id: 578455:THITE_2106692
uniprot id: G2QR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

578455:THITE 114904
gene id: 578455:THITE_114904
uniprot id: G2RFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

578455:THITE 2106953
gene id: 578455:THITE_2106953
uniprot id: G2QS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

578455:THITE 66464
gene id: 578455:THITE_66464
uniprot id: G2R4F6
names: Similarity
messages: Belongs to the PPP phosphatase family.

578455:THITE 2073073
gene id: 578455:THITE_2073073
uniprot id: G2QWH1
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

578455:THITE 2120135
gene id: 578455:THITE_2120135
uniprot id: G2R9L1
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2109429
gene id: 578455:THITE_2109429
uniprot id: G2QVQ2
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2117434
gene id: 578455:THITE_2117434
uniprot id: G2R820
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

578455:THITE 72015
gene id: 578455:THITE_72015
uniprot id: G2R9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

578455:THITE 70031
gene id: 578455:THITE_70031
uniprot id: G2QVL9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 43396
gene id: 578455:THITE_43396
uniprot id: G2R901
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

578455:THITE 121452
gene id: 578455:THITE_121452
uniprot id: G2R956
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 52833
gene id: 578455:THITE_52833
uniprot id: G2R656
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

578455:THITE 2130140
gene id: 578455:THITE_2130140
uniprot id: G2R602
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

578455:THITE 129457
gene id: 578455:THITE_129457
uniprot id: G2QX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EFG1/PHD1/stuA family.
messages: Nucleus

578455:THITE 2116894
gene id: 578455:THITE_2116894
uniprot id: G2R796
names: Similarity
messages: In the 2nd section; belongs to the type-I 3-dehydroquinase family.
messages: In the N-terminal section; belongs to the shikimate kinase family.

578455:THITE 2150738
gene id: 578455:THITE_2150738
uniprot id: G2R642
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

578455:THITE 2049423
gene id: 578455:THITE_2049423
uniprot id: G2R7D7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2170336
gene id: 578455:THITE_2170336
uniprot id: G2R227
names: Similarity
messages: Belongs to the TFIIB family.

578455:THITE 2142635
gene id: 578455:THITE_2142635
uniprot id: G2R0U1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111578
gene id: 578455:THITE_2111578
uniprot id: G2R2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

578455:THITE 2086982
gene id: 578455:THITE_2086982
uniprot id: G2QZI1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2120270
gene id: 578455:THITE_2120270
uniprot id: G2R9X6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2086510
gene id: 578455:THITE_2086510
uniprot id: G2R2Q9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.

578455:THITE 2042204
gene id: 578455:THITE_2042204
uniprot id: G2QSP7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2066678
gene id: 578455:THITE_2066678
uniprot id: G2R5H7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2108092
gene id: 578455:THITE_2108092
uniprot id: G2QXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA.
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2119843
gene id: 578455:THITE_2119843
uniprot id: G2R8Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.
messages: Nucleus

578455:THITE 2064683
gene id: 578455:THITE_2064683
uniprot id: G2R3M6
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2106599
gene id: 578455:THITE_2106599
uniprot id: G2QQM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

578455:THITE 2115011
gene id: 578455:THITE_2115011
uniprot id: G2R2M6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

578455:THITE 2119967
gene id: 578455:THITE_2119967
uniprot id: G2R995
names: Similarity
messages: Belongs to the GcvT family. CAF17 subfamily.

578455:THITE 2111493
gene id: 578455:THITE_2111493
uniprot id: G2R2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

578455:THITE 2125012
gene id: 578455:THITE_2125012
uniprot id: G2QXA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2114471
gene id: 578455:THITE_2114471
uniprot id: G2QZQ7
names: Similarity
messages: Belongs to the DDB1 family.

578455:THITE 2121038
gene id: 578455:THITE_2121038
uniprot id: G2REC1
names: Similarity
messages: Belongs to the COG4 family.

578455:THITE 2077070
gene id: 578455:THITE_2077070
uniprot id: G2R1K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

578455:THITE 2144616
gene id: 578455:THITE_2144616
uniprot id: G2QZS1
names: Similarity
messages: Belongs to the peptidase S10 family.

578455:THITE 2111496
gene id: 578455:THITE_2111496
uniprot id: G2R2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

578455:THITE 2107325
gene id: 578455:THITE_2107325
uniprot id: G2QTQ7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

578455:THITE 2171733
gene id: 578455:THITE_2171733
uniprot id: G2RGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2110208
gene id: 578455:THITE_2110208
uniprot id: G2QS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

578455:THITE 129749
gene id: 578455:THITE_129749
uniprot id: G2QV38
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

578455:THITE 2122236
gene id: 578455:THITE_2122236
uniprot id: G2RCH3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2169523
gene id: 578455:THITE_2169523
uniprot id: G2QUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

578455:THITE 2121106
gene id: 578455:THITE_2121106
uniprot id: G2REF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

578455:THITE 2112374
gene id: 578455:THITE_2112374
uniprot id: G2QYM5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 75719
gene id: 578455:THITE_75719
uniprot id: G2RFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

578455:THITE 2115235
gene id: 578455:THITE_2115235
uniprot id: G2R3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

578455:THITE 2107726
gene id: 578455:THITE_2107726
uniprot id: G2QUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

578455:THITE 123992
gene id: 578455:THITE_123992
uniprot id: G2QVY4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2120874
gene id: 578455:THITE_2120874
uniprot id: G2RDV2
names: Similarity
messages: Belongs to the Tim44 family.

578455:THITE 2116393
gene id: 578455:THITE_2116393
uniprot id: G2R5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBT5 family.
messages: Membrane
messages: cell wall

578455:THITE 2114086
gene id: 578455:THITE_2114086
uniprot id: G2R593
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2027442
gene id: 578455:THITE_2027442
uniprot id: G2QXA1
names: Function
names: Similarity
messages: Belongs to the MBF1 family.
messages: Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators.

578455:THITE 2119641
gene id: 578455:THITE_2119641
uniprot id: G2RC25
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2108629
gene id: 578455:THITE_2108629
uniprot id: G2QS22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2141597
gene id: 578455:THITE_2141597
uniprot id: G2QSY5
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2046631
gene id: 578455:THITE_2046631
uniprot id: G2R111
names: Similarity
messages: Belongs to the TBP family.

578455:THITE 2118436
gene id: 578455:THITE_2118436
uniprot id: G2RA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate.
messages: Vacuole

578455:THITE 2121510
gene id: 578455:THITE_2121510
uniprot id: G2RF01
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

578455:THITE 2118310
gene id: 578455:THITE_2118310
uniprot id: G2R9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

578455:THITE 2111957
gene id: 578455:THITE_2111957
uniprot id: G2R450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion

578455:THITE 2116105
gene id: 578455:THITE_2116105
uniprot id: G2QZV9
names: Similarity
messages: Belongs to the MIX23 family.

578455:THITE 2114564
gene id: 578455:THITE_2114564
uniprot id: G2R0J1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

578455:THITE 131200
gene id: 578455:THITE_131200
uniprot id: G2QWD2
names: Similarity
messages: Belongs to the peptidase A1 family.

578455:THITE 2141752
gene id: 578455:THITE_2141752
uniprot id: G2QUE7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

578455:THITE 163916
gene id: 578455:THITE_163916
uniprot id: G2RF34
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

578455:THITE 2117024
gene id: 578455:THITE_2117024
uniprot id: G2R7G6
names: Function
messages: Required for the assembly of cytochrome c oxidase.

578455:THITE 2154626
gene id: 578455:THITE_2154626
uniprot id: G2R2M7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2120989
gene id: 578455:THITE_2120989
uniprot id: G2RE48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.

578455:THITE 2108762
gene id: 578455:THITE_2108762
uniprot id: G2QSH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

578455:THITE 2112724
gene id: 578455:THITE_2112724
uniprot id: G2R0C4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2052808
gene id: 578455:THITE_2052808
uniprot id: G2R978
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

578455:THITE 2124731
gene id: 578455:THITE_2124731
uniprot id: G2RGH2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: Membrane
messages: actin patch

578455:THITE 2111501
gene id: 578455:THITE_2111501
uniprot id: G2R2Q0
names: Similarity
messages: Belongs to the SLA2 family.

578455:THITE 2122373
gene id: 578455:THITE_2122373
uniprot id: G2RCZ8
names: Similarity
messages: Belongs to the peptidase C48 family.

578455:THITE 127590
gene id: 578455:THITE_127590
uniprot id: G2QQU8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

578455:THITE 2043508
gene id: 578455:THITE_2043508
uniprot id: G2QZC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

578455:THITE 2112741
gene id: 578455:THITE_2112741
uniprot id: G2R0D5
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2110312
gene id: 578455:THITE_2110312
uniprot id: G2QSB5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

578455:THITE 2073385
gene id: 578455:THITE_2073385
uniprot id: G2QRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

578455:THITE 2082851
gene id: 578455:THITE_2082851
uniprot id: G2RHK4
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

578455:THITE 2106074
gene id: 578455:THITE_2106074
uniprot id: G2QW18
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 49160
gene id: 578455:THITE_49160
uniprot id: G2QTN3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2061803
gene id: 578455:THITE_2061803
uniprot id: G2QRZ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

578455:THITE 2112938
gene id: 578455:THITE_2112938
uniprot id: G2R1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 2144780
gene id: 578455:THITE_2144780
uniprot id: G2R8I9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106222
gene id: 578455:THITE_2106222
uniprot id: G2QWP4
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

578455:THITE 2118294
gene id: 578455:THITE_2118294
uniprot id: G2R9M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: cytoskeleton

578455:THITE 2111384
gene id: 578455:THITE_2111384
uniprot id: G2R2A0
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

578455:THITE 2051934
gene id: 578455:THITE_2051934
uniprot id: G2R5U2
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

578455:THITE 2110770
gene id: 578455:THITE_2110770
uniprot id: G2QUH8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

578455:THITE 2124530
gene id: 578455:THITE_2124530
uniprot id: G2RFY0
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

578455:THITE 2108308
gene id: 578455:THITE_2108308
uniprot id: G2QQR6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

578455:THITE 2124573
gene id: 578455:THITE_2124573
uniprot id: G2RG02
names: Similarity
messages: Belongs to the syntaxin family.

578455:THITE 2053513
gene id: 578455:THITE_2053513
uniprot id: G2RBA7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

578455:THITE 2080723
gene id: 578455:THITE_2080723
uniprot id: G2R9S6
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

578455:THITE 2117052
gene id: 578455:THITE_2117052
uniprot id: G2R7I0
names: Similarity
messages: Belongs to the peptidase M28 family.

578455:THITE 2112048
gene id: 578455:THITE_2112048
uniprot id: G2R4K3
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2117674
gene id: 578455:THITE_2117674
uniprot id: G2R8H9
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.

578455:THITE 2119541
gene id: 578455:THITE_2119541
uniprot id: G2RBY0
names: Similarity
messages: Belongs to the isochorismatase family.

578455:THITE 2114329
gene id: 578455:THITE_2114329
uniprot id: G2QZ74
names: Similarity
messages: Belongs to the EIF1AD family.

578455:THITE 2118727
gene id: 578455:THITE_2118727
uniprot id: G2RAN6
names: Function
names: Subcellular Location Annotation
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
messages: nucleolus

578455:THITE 2117644
gene id: 578455:THITE_2117644
uniprot id: G2R8G3
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2107320
gene id: 578455:THITE_2107320
uniprot id: G2QTQ5
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111426
gene id: 578455:THITE_2111426
uniprot id: G2R2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2116489
gene id: 578455:THITE_2116489
uniprot id: G2R6D0
names: Similarity
messages: Belongs to the caleosin family.

578455:THITE 2109842
gene id: 578455:THITE_2109842
uniprot id: G2QY15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

578455:THITE 16677
gene id: 578455:THITE_16677
uniprot id: G2R708
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

578455:THITE 2046563
gene id: 578455:THITE_2046563
uniprot id: G2R0X9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2060441
gene id: 578455:THITE_2060441
uniprot id: G2QW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2120778
gene id: 578455:THITE_2120778
uniprot id: G2RDR3
names: Subcellular Location Annotation
messages: Cytoplasm

578455:THITE 2106853
gene id: 578455:THITE_2106853
uniprot id: G2QRW2
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

578455:THITE 2144537
gene id: 578455:THITE_2144537
uniprot id: G2QYU5
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2124050
gene id: 578455:THITE_2124050
uniprot id: G2RI75
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

578455:THITE 2113125
gene id: 578455:THITE_2113125
uniprot id: G2R1X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

578455:THITE 2121540
gene id: 578455:THITE_2121540
uniprot id: G2RF17
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2120664
gene id: 578455:THITE_2120664
uniprot id: G2RD65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2080789
gene id: 578455:THITE_2080789
uniprot id: G2R9W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

578455:THITE 109910
gene id: 578455:THITE_109910
uniprot id: G2R0P6
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

578455:THITE 2119830
gene id: 578455:THITE_2119830
uniprot id: G2R8Y0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs.

578455:THITE 2121970
gene id: 578455:THITE_2121970
uniprot id: G2RFJ0
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

578455:THITE 2142830
gene id: 578455:THITE_2142830
uniprot id: G2R359
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

578455:THITE 2106346
gene id: 578455:THITE_2106346
uniprot id: G2QX85
names: Subcellular Location Annotation
messages: Peroxisome membrane

578455:THITE 2117092
gene id: 578455:THITE_2117092
uniprot id: G2R7K5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.
messages: Component of the SWR1 chromatin-remodeling complex.
messages: Nucleus

578455:THITE 2080212
gene id: 578455:THITE_2080212
uniprot id: G2RBP9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111794
gene id: 578455:THITE_2111794
uniprot id: G2R3M4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2106558
gene id: 578455:THITE_2106558
uniprot id: G2QQL3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

578455:THITE 2107635
gene id: 578455:THITE_2107635
uniprot id: G2QUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

578455:THITE 2108697
gene id: 578455:THITE_2108697
uniprot id: G2QS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

578455:THITE 70134
gene id: 578455:THITE_70134
uniprot id: G2QWV4
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

578455:THITE 107944
gene id: 578455:THITE_107944
uniprot id: G2QXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.

578455:THITE 2170564
gene id: 578455:THITE_2170564
uniprot id: G2R6M9
names: Similarity
messages: Belongs to the Necrosis inducing protein (NPP1) family.

578455:THITE 2110364
gene id: 578455:THITE_2110364
uniprot id: G2QSP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN.
messages: Cytoplasm

578455:THITE 119498
gene id: 578455:THITE_119498
uniprot id: G2R0Z5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

578455:THITE 125777
gene id: 578455:THITE_125777
uniprot id: G2R5A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

578455:THITE 2142625
gene id: 578455:THITE_2142625
uniprot id: G2QX55
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2110963
gene id: 578455:THITE_2110963
uniprot id: G2QVI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

578455:THITE 2107025
gene id: 578455:THITE_2107025
uniprot id: G2QSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

578455:THITE 2120512
gene id: 578455:THITE_2120512
uniprot id: G2RCJ6
names: Function
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

578455:THITE 2124136
gene id: 578455:THITE_2124136
uniprot id: G2RIC1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

578455:THITE 2123244
gene id: 578455:THITE_2123244
uniprot id: G2QUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cytoskeleton

578455:THITE 2112421
gene id: 578455:THITE_2112421
uniprot id: G2QZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

578455:THITE 161618
gene id: 578455:THITE_161618
uniprot id: G2R3F1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

578455:THITE 2144330
gene id: 578455:THITE_2144330
uniprot id: G2R3Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

578455:THITE 2090735
gene id: 578455:THITE_2090735
uniprot id: G2RBR2
names: Similarity
messages: Belongs to the PRP18 family.

578455:THITE 2124341
gene id: 578455:THITE_2124341
uniprot id: G2RFQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with GET3.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.

578455:THITE 2123375
gene id: 578455:THITE_2123375
uniprot id: G2RH97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2142516
gene id: 578455:THITE_2142516
uniprot id: G2QVI1
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2114782
gene id: 578455:THITE_2114782
uniprot id: G2R1Q4
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

578455:THITE 2120380
gene id: 578455:THITE_2120380
uniprot id: G2RAF4
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

578455:THITE 2123792
gene id: 578455:THITE_2123792
uniprot id: G2RHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

578455:THITE 2113667
gene id: 578455:THITE_2113667
uniprot id: G2R3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2120529
gene id: 578455:THITE_2120529
uniprot id: G2RCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2107939
gene id: 578455:THITE_2107939
uniprot id: G2QWA6
names: Subcellular Location Annotation
messages: Secreted

578455:THITE 2110418
gene id: 578455:THITE_2110418
uniprot id: G2QSR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STAM family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
messages: Endosome membrane
messages: Membrane

578455:THITE 2124500
gene id: 578455:THITE_2124500
uniprot id: G2RFW6
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

578455:THITE 2124568
gene id: 578455:THITE_2124568
uniprot id: G2RFZ9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

578455:THITE 2050738
gene id: 578455:THITE_2050738
uniprot id: G2R7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2109230
gene id: 578455:THITE_2109230
uniprot id: G2QUE4
names: Similarity
messages: Belongs to the peptidase S8 family.

578455:THITE 2141153
gene id: 578455:THITE_2141153
uniprot id: G2QV57
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120303
gene id: 578455:THITE_2120303
uniprot id: G2RA47
names: Similarity
messages: Belongs to the scytalone dehydratase family.

578455:THITE 2119170
gene id: 578455:THITE_2119170
uniprot id: G2RBF4
names: Similarity
names: Subunit
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: Component of the COP9 signalosome (CSN) complex.

578455:THITE 2121904
gene id: 578455:THITE_2121904
uniprot id: G2RFG3
names: Similarity
messages: Belongs to the DEAD box helicase family.

578455:THITE 2111430
gene id: 578455:THITE_2111430
uniprot id: G2R2B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

578455:THITE 2116634
gene id: 578455:THITE_2116634
uniprot id: G2R6Y2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

578455:THITE 2059741
gene id: 578455:THITE_2059741
uniprot id: G2RG51
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2122979
gene id: 578455:THITE_2122979
uniprot id: G2RGE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2124126
gene id: 578455:THITE_2124126
uniprot id: G2RIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

578455:THITE 2130565
gene id: 578455:THITE_2130565
uniprot id: G2RAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2108974
gene id: 578455:THITE_2108974
uniprot id: G2QT23
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

578455:THITE 2108064
gene id: 578455:THITE_2108064
uniprot id: G2QXE3
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

578455:THITE 2113959
gene id: 578455:THITE_2113959
uniprot id: G2R4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

578455:THITE 2117966
gene id: 578455:THITE_2117966
uniprot id: G2R698
names: Similarity
messages: Belongs to the UTP6 family.

578455:THITE 2124387
gene id: 578455:THITE_2124387
uniprot id: G2RFS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2110340
gene id: 578455:THITE_2110340
uniprot id: G2QSN3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

578455:THITE 2122726
gene id: 578455:THITE_2122726
uniprot id: G2RE01
names: Similarity
messages: Belongs to the actin family.

578455:THITE 2110805
gene id: 578455:THITE_2110805
uniprot id: G2QUJ5
names: Similarity
messages: Belongs to the RSP5/NEDD4 family.

578455:THITE 2107763
gene id: 578455:THITE_2107763
uniprot id: G2QV62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

578455:THITE 2115220
gene id: 578455:THITE_2115220
uniprot id: G2R3I9
names: Similarity
messages: Belongs to the FAM214 family.

578455:THITE 2122194
gene id: 578455:THITE_2122194
uniprot id: G2RCD1
names: Similarity
messages: Belongs to the isochorismatase family.

578455:THITE 2114661
gene id: 578455:THITE_2114661
uniprot id: G2R124
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Polynucleotide 5'-kinase involved in rRNA processing.
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

578455:THITE 2120052
gene id: 578455:THITE_2120052
uniprot id: G2R9I5
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

578455:THITE 2141895
gene id: 578455:THITE_2141895
uniprot id: G2QWC5
names: Similarity
messages: Belongs to the polyketide transferase af380 family.

578455:THITE 2077413
gene id: 578455:THITE_2077413
uniprot id: G2R3C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

578455:THITE 122992
gene id: 578455:THITE_122992
uniprot id: G2REP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

578455:THITE 2150123
gene id: 578455:THITE_2150123
uniprot id: G2R3A3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

578455:THITE 2147675
gene id: 578455:THITE_2147675
uniprot id: G2REH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

578455:THITE 2072790
gene id: 578455:THITE_2072790
uniprot id: G2QTQ0
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

578455:THITE 2109732
gene id: 578455:THITE_2109732
uniprot id: G2QXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

578455:THITE 2122567
gene id: 578455:THITE_2122567
uniprot id: G2RDK8
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.

578455:THITE 45100
gene id: 578455:THITE_45100
uniprot id: G2RDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSH4 family.
messages: Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.
messages: Endosome membrane
messages: Membrane
messages: Vacuole membrane

578455:THITE 2110329
gene id: 578455:THITE_2110329
uniprot id: G2QSM8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

578455:THITE 2109847
gene id: 578455:THITE_2109847
uniprot id: G2QY17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

578455:THITE 2147180
gene id: 578455:THITE_2147180
uniprot id: G2RF56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

578455:THITE 2119491
gene id: 578455:THITE_2119491
uniprot id: G2RBW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane
messages: Probable lipid hydrolase.

578455:THITE 2117990
gene id: 578455:THITE_2117990
uniprot id: G2R6B1
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

578455:THITE 2124577
gene id: 578455:THITE_2124577
uniprot id: G2RG04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

578455:THITE 2170472
gene id: 578455:THITE_2170472
uniprot id: G2QYG0
names: Function
names: Subunit
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

578455:THITE 2116548
gene id: 578455:THITE_2116548
uniprot id: G2R6P4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2170572
gene id: 578455:THITE_2170572
uniprot id: G2R6R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

578455:THITE 2119707
gene id: 578455:THITE_2119707
uniprot id: G2RC56
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

578455:THITE 2119559
gene id: 578455:THITE_2119559
uniprot id: G2RBY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

578455:THITE 2037220
gene id: 578455:THITE_2037220
uniprot id: G2QS66
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

578455:THITE 2106743
gene id: 578455:THITE_2106743
uniprot id: G2QRG5
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2110980
gene id: 578455:THITE_2110980
uniprot id: G2QVV4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2111700
gene id: 578455:THITE_2111700
uniprot id: G2R379
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

578455:THITE 133987
gene id: 578455:THITE_133987
uniprot id: G2QW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

578455:THITE 2151119
gene id: 578455:THITE_2151119
uniprot id: G2R916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

578455:THITE 2051591
gene id: 578455:THITE_2051591
uniprot id: G2R765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

578455:THITE 2070828
gene id: 578455:THITE_2070828
uniprot id: G2RGD7
names: Similarity
messages: Belongs to the APC10 family.

578455:THITE 2116019
gene id: 578455:THITE_2116019
uniprot id: G2QZF2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2117076
gene id: 578455:THITE_2117076
uniprot id: G2R7J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

578455:THITE 2155455
gene id: 578455:THITE_2155455
uniprot id: G2RAB3
names: Similarity
messages: Belongs to the taffazin family.

578455:THITE 2119891
gene id: 578455:THITE_2119891
uniprot id: G2R908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

578455:THITE 2114946
gene id: 578455:THITE_2114946
uniprot id: G2R2J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

578455:THITE 2069837
gene id: 578455:THITE_2069837
uniprot id: G2RET1
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

578455:THITE 2039728
gene id: 578455:THITE_2039728
uniprot id: G2QWL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

578455:THITE 2108235
gene id: 578455:THITE_2108235
uniprot id: G2QQP2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112439
gene id: 578455:THITE_2112439
uniprot id: G2QZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

578455:THITE 2116283
gene id: 578455:THITE_2116283
uniprot id: G2R185
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2048755
gene id: 578455:THITE_2048755
uniprot id: G2R5B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2155717
gene id: 578455:THITE_2155717
uniprot id: G2RC29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

578455:THITE 2120602
gene id: 578455:THITE_2120602
uniprot id: G2RCU6
names: Similarity
messages: Belongs to the multicopper oxidase family.

578455:THITE 2122744
gene id: 578455:THITE_2122744
uniprot id: G2RE66
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

578455:THITE 2088921
gene id: 578455:THITE_2088921
uniprot id: G2R8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2110987
gene id: 578455:THITE_2110987
uniprot id: G2QVW2
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

578455:THITE 2112289
gene id: 578455:THITE_2112289
uniprot id: G2QY75
names: Similarity
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.

578455:THITE 2117601
gene id: 578455:THITE_2117601
uniprot id: G2R8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

578455:THITE 2143248
gene id: 578455:THITE_2143248
uniprot id: G2QZX2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2018475
gene id: 578455:THITE_2018475
uniprot id: G2R3E9
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2040152
gene id: 578455:THITE_2040152
uniprot id: G2QW33
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

578455:THITE 2118082
gene id: 578455:THITE_2118082
uniprot id: G2R6W1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123045
gene id: 578455:THITE_2123045
uniprot id: G2RGN0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

578455:THITE 2074679
gene id: 578455:THITE_2074679
uniprot id: G2QTG8
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

578455:THITE 2113432
gene id: 578455:THITE_2113432
uniprot id: G2R2V4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

578455:THITE 2124823
gene id: 578455:THITE_2124823
uniprot id: G2RGU2
names: Similarity
messages: Belongs to the activator 1 small subunits family.

578455:THITE 2109576
gene id: 578455:THITE_2109576
uniprot id: G2QWZ5
names: Similarity
messages: Belongs to the BLM10 family.

578455:THITE 2121503
gene id: 578455:THITE_2121503
uniprot id: G2REZ7
names: Function
names: Similarity
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.

578455:THITE 2074062
gene id: 578455:THITE_2074062
uniprot id: G2QWV7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

578455:THITE 2106420
gene id: 578455:THITE_2106420
uniprot id: G2QXM4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

578455:THITE 135666
gene id: 578455:THITE_135666
uniprot id: G2QTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

578455:THITE 2079007
gene id: 578455:THITE_2079007
uniprot id: G2R860
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

578455:THITE 2122268
gene id: 578455:THITE_2122268
uniprot id: G2RCN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

578455:THITE 2121964
gene id: 578455:THITE_2121964
uniprot id: G2RFI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

578455:THITE 2120922
gene id: 578455:THITE_2120922
uniprot id: G2RE25
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 74570
gene id: 578455:THITE_74570
uniprot id: G2QU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2118793
gene id: 578455:THITE_2118793
uniprot id: G2RAW3
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2116896
gene id: 578455:THITE_2116896
uniprot id: G2R798
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

578455:THITE 2106430
gene id: 578455:THITE_2106430
uniprot id: G2QXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

578455:THITE 2118892
gene id: 578455:THITE_2118892
uniprot id: G2RB09
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2170283
gene id: 578455:THITE_2170283
uniprot id: G2R027
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

578455:THITE 2121216
gene id: 578455:THITE_2121216
uniprot id: G2REN6
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

578455:THITE 2090942
gene id: 578455:THITE_2090942
uniprot id: G2R905
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

578455:THITE 2110409
gene id: 578455:THITE_2110409
uniprot id: G2QSR3
names: Similarity
messages: Belongs to the PhyH family.

578455:THITE 2124334
gene id: 578455:THITE_2124334
uniprot id: G2RFQ2
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 35966
gene id: 578455:THITE_35966
uniprot id: G2R1A9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123493
gene id: 578455:THITE_2123493
uniprot id: G2RHI3
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

578455:THITE 2106660
gene id: 578455:THITE_2106660
uniprot id: G2QR13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

578455:THITE 2116818
gene id: 578455:THITE_2116818
uniprot id: G2R762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SQS1 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2066420
gene id: 578455:THITE_2066420
uniprot id: G2R121
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

578455:THITE 2115403
gene id: 578455:THITE_2115403
uniprot id: G2R4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

578455:THITE 2110940
gene id: 578455:THITE_2110940
uniprot id: G2QVG5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

578455:THITE 2121828
gene id: 578455:THITE_2121828
uniprot id: G2RFC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

578455:THITE 2108019
gene id: 578455:THITE_2108019
uniprot id: G2QWV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

578455:THITE 170170
gene id: 578455:THITE_170170
uniprot id: G2R8Q8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

578455:THITE 2122806
gene id: 578455:THITE_2122806
uniprot id: G2RE93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

578455:THITE 2107520
gene id: 578455:THITE_2107520
uniprot id: G2QU79
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

578455:THITE 2119570
gene id: 578455:THITE_2119570
uniprot id: G2RBZ0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2109818
gene id: 578455:THITE_2109818
uniprot id: G2QY03
names: Similarity
messages: Belongs to the FPG family.

578455:THITE 120638
gene id: 578455:THITE_120638
uniprot id: G2QTB3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

578455:THITE 2110885
gene id: 578455:THITE_2110885
uniprot id: G2QUZ1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 119017
gene id: 578455:THITE_119017
uniprot id: G2QZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

578455:THITE 2156588
gene id: 578455:THITE_2156588
uniprot id: G2RH82
names: Similarity
messages: Belongs to the TCF25 family.

578455:THITE 76240
gene id: 578455:THITE_76240
uniprot id: G2R5Y0
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

578455:THITE 2110690
gene id: 578455:THITE_2110690
uniprot id: G2QU44
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

578455:THITE 2065460
gene id: 578455:THITE_2065460
uniprot id: G2R1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

578455:THITE 2115183
gene id: 578455:THITE_2115183
uniprot id: G2R3H1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

578455:THITE 2149004
gene id: 578455:THITE_2149004
uniprot id: G2QQQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

578455:THITE 2112784
gene id: 578455:THITE_2112784
uniprot id: G2R0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

578455:THITE 2149730
gene id: 578455:THITE_2149730
uniprot id: G2R389
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122630
gene id: 578455:THITE_2122630
uniprot id: G2RDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

578455:THITE 2141821
gene id: 578455:THITE_2141821
uniprot id: G2QV93
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

578455:THITE 2123688
gene id: 578455:THITE_2123688
uniprot id: G2RHS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. SEC13 and SEC31 make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple copies to form the complete polyhedral cage. Interacts (via WD 8) with SEC13.

578455:THITE 2116074
gene id: 578455:THITE_2116074
uniprot id: G2QZU4
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

578455:THITE 2117640
gene id: 578455:THITE_2117640
uniprot id: G2R8F8
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

578455:THITE 2146542
gene id: 578455:THITE_2146542
uniprot id: G2R9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

578455:THITE 2074797
gene id: 578455:THITE_2074797
uniprot id: G2QUE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.
messages: Secreted

578455:THITE 2116382
gene id: 578455:THITE_2116382
uniprot id: G2R5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

578455:THITE 2124576
gene id: 578455:THITE_2124576
uniprot id: G2RG03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

578455:THITE 2115532
gene id: 578455:THITE_2115532
uniprot id: G2R4V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

578455:THITE 2110071
gene id: 578455:THITE_2110071
uniprot id: G2QRE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

578455:THITE 2114620
gene id: 578455:THITE_2114620
uniprot id: G2R0M5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

578455:THITE 2108097
gene id: 578455:THITE_2108097
uniprot id: G2QXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cerato-platanin family.
messages: Secreted

578455:THITE 71399
gene id: 578455:THITE_71399
uniprot id: G2RB69
names: Similarity
messages: Belongs to the MAPRE family.

578455:THITE 2171105
gene id: 578455:THITE_2171105
uniprot id: G2RA78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

578455:THITE 2124841
gene id: 578455:THITE_2124841
uniprot id: G2RGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

578455:THITE 2041371
gene id: 578455:THITE_2041371
uniprot id: G2QRS4
names: Similarity
messages: Belongs to the DapA family.

578455:THITE 2110751
gene id: 578455:THITE_2110751
uniprot id: G2QUG9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113587
gene id: 578455:THITE_2113587
uniprot id: G2R3C8
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

578455:THITE 2106512
gene id: 578455:THITE_2106512
uniprot id: G2QQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

578455:THITE 2116651
gene id: 578455:THITE_2116651
uniprot id: G2R6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

578455:THITE 2041986
gene id: 578455:THITE_2041986
uniprot id: G2QS04
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

578455:THITE 128080
gene id: 578455:THITE_128080
uniprot id: G2R5P7
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 46900
gene id: 578455:THITE_46900
uniprot id: G2RCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 75 family.
messages: Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.
messages: Secreted

578455:THITE 2119866
gene id: 578455:THITE_2119866
uniprot id: G2R8Z7
names: Function
names: Subcellular Location Annotation
messages: May act as a zinc-influx transporter.
messages: Membrane

578455:THITE 2109142
gene id: 578455:THITE_2109142
uniprot id: G2QTW4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

578455:THITE 2171333
gene id: 578455:THITE_2171333
uniprot id: G2RFG1
names: Similarity
messages: Belongs to the 14-3-3 family.

578455:THITE 70334
gene id: 578455:THITE_70334
uniprot id: G2QQT4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113311
gene id: 578455:THITE_2113311
uniprot id: G2R2E9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2119946
gene id: 578455:THITE_2119946
uniprot id: G2R983
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

578455:THITE 2120288
gene id: 578455:THITE_2120288
uniprot id: G2RA38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
messages: Nucleus

578455:THITE 2113534
gene id: 578455:THITE_2113534
uniprot id: G2R3A9
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120630
gene id: 578455:THITE_2120630
uniprot id: G2RCY5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX4 family.
messages: Forms a heterodimer with SLX1.
messages: Nucleus
messages: Phosphorylated in response to DNA damage.
messages: Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.

578455:THITE 2119337
gene id: 578455:THITE_2119337
uniprot id: G2RBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

578455:THITE 2113066
gene id: 578455:THITE_2113066
uniprot id: G2R1J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
messages: Vacuole membrane

578455:THITE 66668
gene id: 578455:THITE_66668
uniprot id: G2R338
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

578455:THITE 2106179
gene id: 578455:THITE_2106179
uniprot id: G2QWM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

578455:THITE 135170
gene id: 578455:THITE_135170
uniprot id: G2REY4
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2108283
gene id: 578455:THITE_2108283
uniprot id: G2QQQ8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2112263
gene id: 578455:THITE_2112263
uniprot id: G2QY61
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118362
gene id: 578455:THITE_2118362
uniprot id: G2R9R4
names: Similarity
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.

578455:THITE 2056521
gene id: 578455:THITE_2056521
uniprot id: G2RCE3
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2044060
gene id: 578455:THITE_2044060
uniprot id: G2R2H8
names: Similarity
messages: Belongs to the UPP synthase family.

578455:THITE 2117654
gene id: 578455:THITE_2117654
uniprot id: G2R8G9
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2114309
gene id: 578455:THITE_2114309
uniprot id: G2QZ67
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

578455:THITE 2020551
gene id: 578455:THITE_2020551
uniprot id: G2RB03
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 46814
gene id: 578455:THITE_46814
uniprot id: G2RFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

578455:THITE 2117348
gene id: 578455:THITE_2117348
uniprot id: G2R7Y4
names: Similarity
messages: Belongs to the MIT1/WOR1 family.

578455:THITE 2086847
gene id: 578455:THITE_2086847
uniprot id: G2QY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2107828
gene id: 578455:THITE_2107828
uniprot id: G2QVL2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2109691
gene id: 578455:THITE_2109691
uniprot id: G2QXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS27 family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
messages: Endosome membrane
messages: Membrane

578455:THITE 2123261
gene id: 578455:THITE_2123261
uniprot id: G2RH25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

578455:THITE 2076863
gene id: 578455:THITE_2076863
uniprot id: G2R009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 61 family.
messages: Secreted

578455:THITE 2118804
gene id: 578455:THITE_2118804
uniprot id: G2RAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

578455:THITE 2110162
gene id: 578455:THITE_2110162
uniprot id: G2QRT7
names: Similarity
messages: Belongs to the neutral ceramidase family.

578455:THITE 2110797
gene id: 578455:THITE_2110797
uniprot id: G2QUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

578455:THITE 36773
gene id: 578455:THITE_36773
uniprot id: G2R372
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

578455:THITE 2113728
gene id: 578455:THITE_2113728
uniprot id: G2R3V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

578455:THITE 2114423
gene id: 578455:THITE_2114423
uniprot id: G2QZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

578455:THITE 2110175
gene id: 578455:THITE_2110175
uniprot id: G2QRU6
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

578455:THITE 2040718
gene id: 578455:THITE_2040718
uniprot id: G2QUN0
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.

578455:THITE 63893
gene id: 578455:THITE_63893
uniprot id: G2RHK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

578455:THITE 2123828
gene id: 578455:THITE_2123828
uniprot id: G2RHZ5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

578455:THITE 2122420
gene id: 578455:THITE_2122420
uniprot id: G2RD27
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 2155132
gene id: 578455:THITE_2155132
uniprot id: G2R7S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

578455:THITE 2107365
gene id: 578455:THITE_2107365
uniprot id: G2QTR9
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

578455:THITE 2123979
gene id: 578455:THITE_2123979
uniprot id: G2RI52
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122272
gene id: 578455:THITE_2122272
uniprot id: G2RCP1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2114623
gene id: 578455:THITE_2114623
uniprot id: G2R0M6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2119140
gene id: 578455:THITE_2119140
uniprot id: G2RBE2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2085894
gene id: 578455:THITE_2085894
uniprot id: G2QT68
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

578455:THITE 2121064
gene id: 578455:THITE_2121064
uniprot id: G2RED3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

578455:THITE 2106651
gene id: 578455:THITE_2106651
uniprot id: G2QR09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

578455:THITE 2117306
gene id: 578455:THITE_2117306
uniprot id: G2R7V8
names: Similarity
messages: Belongs to the protein kinase superfamily.

578455:THITE 2114717
gene id: 578455:THITE_2114717
uniprot id: G2R1M2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

578455:THITE 2113700
gene id: 578455:THITE_2113700
uniprot id: G2R3U0
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107410
gene id: 578455:THITE_2107410
uniprot id: G2QTT9
names: Similarity
messages: Belongs to the peptidase M14 family.

578455:THITE 2059924
gene id: 578455:THITE_2059924
uniprot id: G2RI40
names: Similarity
messages: Belongs to the actin family.

578455:THITE 2107775
gene id: 578455:THITE_2107775
uniprot id: G2QV68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

578455:THITE 152152
gene id: 578455:THITE_152152
uniprot id: G2QZM2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: telomere

578455:THITE 41067
gene id: 578455:THITE_41067
uniprot id: G2QWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

578455:THITE 2107530
gene id: 578455:THITE_2107530
uniprot id: G2QU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

578455:THITE 2122170
gene id: 578455:THITE_2122170
uniprot id: G2RCB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

578455:THITE 2096832
gene id: 578455:THITE_2096832
uniprot id: G2R9T1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

578455:THITE 2117062
gene id: 578455:THITE_2117062
uniprot id: G2R7I6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

578455:THITE 2118763
gene id: 578455:THITE_2118763
uniprot id: G2RAV6
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

578455:THITE 2108295
gene id: 578455:THITE_2108295
uniprot id: G2QQR2
names: Similarity
messages: Belongs to the syntaxin family.

578455:THITE 2154403
gene id: 578455:THITE_2154403
uniprot id: G2R4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 113981
gene id: 578455:THITE_113981
uniprot id: G2RBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

578455:THITE 2108456
gene id: 578455:THITE_2108456
uniprot id: G2QR93
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113878
gene id: 578455:THITE_2113878
uniprot id: G2R4C4
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

578455:THITE 2126029
gene id: 578455:THITE_2126029
uniprot id: G2QT07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

578455:THITE 2113782
gene id: 578455:THITE_2113782
uniprot id: G2R485
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

578455:THITE 2122898
gene id: 578455:THITE_2122898
uniprot id: G2RG48
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

578455:THITE 2107200
gene id: 578455:THITE_2107200
uniprot id: G2QTA0
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

578455:THITE 42297
gene id: 578455:THITE_42297
uniprot id: G2R965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

578455:THITE 2123151
gene id: 578455:THITE_2123151
uniprot id: G2RGS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2109326
gene id: 578455:THITE_2109326
uniprot id: G2QUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cytoskeleton

578455:THITE 2119973
gene id: 578455:THITE_2119973
uniprot id: G2R9A0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

578455:THITE 14941
gene id: 578455:THITE_14941
uniprot id: G2QRA2
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

578455:THITE 2111382
gene id: 578455:THITE_2111382
uniprot id: G2R299
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2060163
gene id: 578455:THITE_2060163
uniprot id: G2RHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

578455:THITE 2107345
gene id: 578455:THITE_2107345
uniprot id: G2QTR2
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

578455:THITE 2122357
gene id: 578455:THITE_2122357
uniprot id: G2RCT4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2057505
gene id: 578455:THITE_2057505
uniprot id: G2RCH0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2116933
gene id: 578455:THITE_2116933
uniprot id: G2R7B5
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

578455:THITE 2124766
gene id: 578455:THITE_2124766
uniprot id: G2RGK7
names: Function
names: Similarity
messages: Belongs to the MUB1/samB family.
messages: Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.

578455:THITE 2083750
gene id: 578455:THITE_2083750
uniprot id: G2QW53
names: Similarity
messages: Belongs to the GST superfamily.

578455:THITE 2156422
gene id: 578455:THITE_2156422
uniprot id: G2RDN6
names: Similarity
messages: Belongs to the phospholipase D family.

578455:THITE 2076069
gene id: 578455:THITE_2076069
uniprot id: G2R0B7
names: Subcellular Location Annotation
messages: nuclear pore complex

578455:THITE 127923
gene id: 578455:THITE_127923
uniprot id: G2RI89
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

578455:THITE 2106815
gene id: 578455:THITE_2106815
uniprot id: G2QRJ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

578455:THITE 2034205
gene id: 578455:THITE_2034205
uniprot id: G2R6L3
names: Similarity
messages: Belongs to the UbiA prenyltransferase family.

578455:THITE 2119222
gene id: 578455:THITE_2119222
uniprot id: G2RBH5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

578455:THITE 2120481
gene id: 578455:THITE_2120481
uniprot id: G2RAS7
names: Similarity
messages: Belongs to the CHS7 family.

578455:THITE 131997
gene id: 578455:THITE_131997
uniprot id: G2R6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

578455:THITE 67248
gene id: 578455:THITE_67248
uniprot id: G2QY91
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

578455:THITE 122312
gene id: 578455:THITE_122312
uniprot id: G2RAP7
names: Similarity
messages: Belongs to the IlvD/Edd family.

578455:THITE 2111320
gene id: 578455:THITE_2111320
uniprot id: G2R1U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

578455:THITE 2049026
gene id: 578455:THITE_2049026
uniprot id: G2R1V8
names: Similarity
messages: Belongs to the cytochrome P450 family.

578455:THITE 2116076
gene id: 578455:THITE_2116076
uniprot id: G2QZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

578455:THITE 2117283
gene id: 578455:THITE_2117283
uniprot id: G2R7U6
names: Similarity
messages: Belongs to the RMD1/sif2 family.

578455:THITE 2117322
gene id: 578455:THITE_2117322
uniprot id: G2R7W6
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2087527
gene id: 578455:THITE_2087527
uniprot id: G2R4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2048425
gene id: 578455:THITE_2048425
uniprot id: G2R2W8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2120008
gene id: 578455:THITE_2120008
uniprot id: G2R9H2
names: Similarity
messages: Belongs to the peptidase M18 family.

578455:THITE 2124791
gene id: 578455:THITE_2124791
uniprot id: G2RGS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

578455:THITE 2169707
gene id: 578455:THITE_2169707
uniprot id: G2QU47
names: Subunit
messages: Homodimer.

578455:THITE 2111461
gene id: 578455:THITE_2111461
uniprot id: G2R2C7
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2107753
gene id: 578455:THITE_2107753
uniprot id: G2QV46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

578455:THITE 2114473
gene id: 578455:THITE_2114473
uniprot id: G2R018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

578455:THITE 41253
gene id: 578455:THITE_41253
uniprot id: G2QUB2
names: Subcellular Location Annotation
messages: Nucleus

578455:THITE 2116672
gene id: 578455:THITE_2116672
uniprot id: G2R6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2152932
gene id: 578455:THITE_2152932
uniprot id: G2QU81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

578455:THITE 2120180
gene id: 578455:THITE_2120180
uniprot id: G2R9S7
names: Similarity
messages: Belongs to the CCS1 family.
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

578455:THITE 2110465
gene id: 578455:THITE_2110465
uniprot id: G2QT42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
messages: Membrane

578455:THITE 2143978
gene id: 578455:THITE_2143978
uniprot id: G2R041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 44263
gene id: 578455:THITE_44263
uniprot id: G2RBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2122581
gene id: 578455:THITE_2122581
uniprot id: G2RDL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 2110796
gene id: 578455:THITE_2110796
uniprot id: G2QUJ0
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

578455:THITE 2120852
gene id: 578455:THITE_2120852
uniprot id: G2RDU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

578455:THITE 2114542
gene id: 578455:THITE_2114542
uniprot id: G2R060
names: Similarity
messages: Belongs to the peptidase M28 family.

578455:THITE 2107196
gene id: 578455:THITE_2107196
uniprot id: G2QT99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

578455:THITE 2123918
gene id: 578455:THITE_2123918
uniprot id: G2RI29
names: Similarity
messages: Belongs to the ZPR1 family.

578455:THITE 2120880
gene id: 578455:THITE_2120880
uniprot id: G2RE11
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

578455:THITE 2118200
gene id: 578455:THITE_2118200
uniprot id: G2R927
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

578455:THITE 2108492
gene id: 578455:THITE_2108492
uniprot id: G2QRL4
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2055159
gene id: 578455:THITE_2055159
uniprot id: G2RAF9
names: Similarity
messages: Belongs to the peptidase C1 family.

578455:THITE 2171720
gene id: 578455:THITE_2171720
uniprot id: G2RGA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

578455:THITE 2120241
gene id: 578455:THITE_2120241
uniprot id: G2R9V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

578455:THITE 122544
gene id: 578455:THITE_122544
uniprot id: G2RD28
names: Similarity
messages: Belongs to the pectinesterase family.

578455:THITE 2115493
gene id: 578455:THITE_2115493
uniprot id: G2R4U2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

578455:THITE 2119471
gene id: 578455:THITE_2119471
uniprot id: G2RBU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

578455:THITE 2117414
gene id: 578455:THITE_2117414
uniprot id: G2R813
names: Similarity
messages: Belongs to the TMA16 family.

578455:THITE 2065964
gene id: 578455:THITE_2065964
uniprot id: G2R4N7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

578455:THITE 2012445
gene id: 578455:THITE_2012445
uniprot id: G2QRT8
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2115689
gene id: 578455:THITE_2115689
uniprot id: G2R5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

578455:THITE 2112745
gene id: 578455:THITE_2112745
uniprot id: G2R0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

578455:THITE 2107907
gene id: 578455:THITE_2107907
uniprot id: G2QW84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

578455:THITE 2123803
gene id: 578455:THITE_2123803
uniprot id: G2RHY4
names: Similarity
messages: Belongs to the NifU family.

578455:THITE 2121196
gene id: 578455:THITE_2121196
uniprot id: G2REM7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

578455:THITE 32886
gene id: 578455:THITE_32886
uniprot id: G2R3T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

578455:THITE 2112832
gene id: 578455:THITE_2112832
uniprot id: G2R0W2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

578455:THITE 2110311
gene id: 578455:THITE_2110311
uniprot id: G2QSB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

578455:THITE 2115888
gene id: 578455:THITE_2115888
uniprot id: G2QYV3
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 124700
gene id: 578455:THITE_124700
uniprot id: G2RG14
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.

578455:THITE 59711
gene id: 578455:THITE_59711
uniprot id: G2RB31
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

578455:THITE 2123179
gene id: 578455:THITE_2123179
uniprot id: G2RGY7
names: Similarity
messages: Belongs to the RENT3 family.

578455:THITE 2107341
gene id: 578455:THITE_2107341
uniprot id: G2QTR1
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2122621
gene id: 578455:THITE_2122621
uniprot id: G2RDN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

578455:THITE 2121318
gene id: 578455:THITE_2121318
uniprot id: G2RET0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

578455:THITE 2124648
gene id: 578455:THITE_2124648
uniprot id: G2RG66
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

578455:THITE 2123387
gene id: 578455:THITE_2123387
uniprot id: G2RHA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

578455:THITE 2108274
gene id: 578455:THITE_2108274
uniprot id: G2QQQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

578455:THITE 2107855
gene id: 578455:THITE_2107855
uniprot id: G2QVM7
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 33410
gene id: 578455:THITE_33410
uniprot id: G2R397
names: Similarity
messages: Belongs to the GAMAD family.

578455:THITE 2144336
gene id: 578455:THITE_2144336
uniprot id: G2R3Z7
names: Similarity
messages: Belongs to the MT-A70-like family.

578455:THITE 2122126
gene id: 578455:THITE_2122126
uniprot id: G2RC97
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

578455:THITE 2039383
gene id: 578455:THITE_2039383
uniprot id: G2QX00
names: Similarity
messages: Belongs to the MON2 family.

578455:THITE 2125932
gene id: 578455:THITE_2125932
uniprot id: G2QS27
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

578455:THITE 2147951
gene id: 578455:THITE_2147951
uniprot id: G2RHG9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

578455:THITE 2067133
gene id: 578455:THITE_2067133
uniprot id: G2R7P8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

578455:THITE 2106186
gene id: 578455:THITE_2106186
uniprot id: G2QWM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

578455:THITE 157561
gene id: 578455:THITE_157561
uniprot id: G2RD46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

578455:THITE 2111726
gene id: 578455:THITE_2111726
uniprot id: G2R391
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

578455:THITE 2118476
gene id: 578455:THITE_2118476
uniprot id: G2RA20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

578455:THITE 2108112
gene id: 578455:THITE_2108112
uniprot id: G2QXT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

578455:THITE 2097885
gene id: 578455:THITE_2097885
uniprot id: G2RFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

578455:THITE 2108869
gene id: 578455:THITE_2108869
uniprot id: G2QSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.
messages: Nucleus

578455:THITE 2041903
gene id: 578455:THITE_2041903
uniprot id: G2QUJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

578455:THITE 2081525
gene id: 578455:THITE_2081525
uniprot id: G2REV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

578455:THITE 2111952
gene id: 578455:THITE_2111952
uniprot id: G2R449
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

578455:THITE 2111926
gene id: 578455:THITE_2111926
uniprot id: G2R439
names: Similarity
messages: Belongs to the AccD/PCCB family.

578455:THITE 160239
gene id: 578455:THITE_160239
uniprot id: G2R851
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118911
gene id: 578455:THITE_2118911
uniprot id: G2RB22
names: Subcellular Location Annotation
messages: nuclear pore complex

578455:THITE 2107950
gene id: 578455:THITE_2107950
uniprot id: G2QWS2
names: Similarity
messages: Belongs to the cyclin family.

578455:THITE 2109016
gene id: 578455:THITE_2109016
uniprot id: G2QTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

578455:THITE 2122150
gene id: 578455:THITE_2122150
uniprot id: G2RCA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: May form a complex with LTO1.
messages: Nucleus
messages: The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.

578455:THITE 46638
gene id: 578455:THITE_46638
uniprot id: G2RF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

578455:THITE 2114432
gene id: 578455:THITE_2114432
uniprot id: G2QZP1
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

578455:THITE 2107864
gene id: 578455:THITE_2107864
uniprot id: G2QVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

578455:THITE 2122221
gene id: 578455:THITE_2122221
uniprot id: G2RCF1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

578455:THITE 2108933
gene id: 578455:THITE_2108933
uniprot id: G2QT12
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

578455:THITE 2114694
gene id: 578455:THITE_2114694
uniprot id: G2R149
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

578455:THITE 2118672
gene id: 578455:THITE_2118672
uniprot id: G2RAL0
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2113385
gene id: 578455:THITE_2113385
uniprot id: G2R2H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

578455:THITE 2120204
gene id: 578455:THITE_2120204
uniprot id: G2R9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

578455:THITE 2118680
gene id: 578455:THITE_2118680
uniprot id: G2RAL5
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

578455:THITE 2093920
gene id: 578455:THITE_2093920
uniprot id: G2QVP3
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2123986
gene id: 578455:THITE_2123986
uniprot id: G2RI54
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2040798
gene id: 578455:THITE_2040798
uniprot id: G2QY07
names: Subcellular Location Annotation
messages: nucleolus

578455:THITE 135104
gene id: 578455:THITE_135104
uniprot id: G2RFA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm

578455:THITE 2117229
gene id: 578455:THITE_2117229
uniprot id: G2R7S6
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

578455:THITE 2120984
gene id: 578455:THITE_2120984
uniprot id: G2RE46
names: Similarity
messages: Belongs to the NAD kinase family.

578455:THITE 2110384
gene id: 578455:THITE_2110384
uniprot id: G2QSQ2
names: Subcellular Location Annotation
messages: Membrane

578455:THITE 2118833
gene id: 578455:THITE_2118833
uniprot id: G2RAX8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

578455:THITE 2111458
gene id: 578455:THITE_2111458
uniprot id: G2R2C6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

578455:THITE 2111662
gene id: 578455:THITE_2111662
uniprot id: G2R365
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

578455:THITE 2119870
gene id: 578455:THITE_2119870
uniprot id: G2R8Z9
names: Similarity
messages: Belongs to the WD repeat MET30/SCONB/SCON-2 family.