574087:acear RS09580
gene id: 574087:acear_RS09580
uniprot id: D9QS81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS04910
gene id: 574087:acear_RS04910
uniprot id: D9QPL8
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS05505
gene id: 574087:acear_RS05505
uniprot id: D9QPY3
names: Similarity
messages: Belongs to the CdaR family.

574087:acear RS03010
gene id: 574087:acear_RS03010
uniprot id: D9QV41
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

574087:acear RS00200
gene id: 574087:acear_RS00200
uniprot id: D9QSP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

574087:acear RS07730
gene id: 574087:acear_RS07730
uniprot id: D9QR65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

574087:acear RS11840
gene id: 574087:acear_RS11840
uniprot id: D9QUL1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS06215
gene id: 574087:acear_RS06215
uniprot id: D9QQC4
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS09570
gene id: 574087:acear_RS09570
uniprot id: D9QS79
names: Similarity
messages: Belongs to the TrpF family.

574087:acear RS02715
gene id: 574087:acear_RS02715
uniprot id: D9QUY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

574087:acear RS01320
gene id: 574087:acear_RS01320
uniprot id: D9QTM2
names: Similarity
messages: Belongs to the GSP E family.

574087:acear RS03605
gene id: 574087:acear_RS03605
uniprot id: D9QVG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS06760
gene id: 574087:acear_RS06760
uniprot id: D9QQN3
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS08670
gene id: 574087:acear_RS08670
uniprot id: D9QRP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

574087:acear RS11765
gene id: 574087:acear_RS11765
uniprot id: D9QUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

574087:acear RS03625
gene id: 574087:acear_RS03625
uniprot id: D9QVG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

574087:acear RS02200
gene id: 574087:acear_RS02200
uniprot id: D9QUN8
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS06550
gene id: 574087:acear_RS06550
uniprot id: D9QQJ0
names: Similarity
messages: Belongs to the peptidase S16 family.

574087:acear RS03300
gene id: 574087:acear_RS03300
uniprot id: D9QV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

574087:acear RS09025
gene id: 574087:acear_RS09025
uniprot id: D9QRW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

574087:acear RS11850
gene id: 574087:acear_RS11850
uniprot id: D9QUL3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

574087:acear RS05790
gene id: 574087:acear_RS05790
uniprot id: D9QQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

574087:acear RS09560
gene id: 574087:acear_RS09560
uniprot id: D9QS77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

574087:acear RS09470
gene id: 574087:acear_RS09470
uniprot id: D9QS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

574087:acear RS01565
gene id: 574087:acear_RS01565
uniprot id: D9QU41
names: Similarity
messages: Belongs to the peptidase S41A family.

574087:acear RS00925
gene id: 574087:acear_RS00925
uniprot id: D9QTE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

574087:acear RS09610
gene id: 574087:acear_RS09610
uniprot id: D9QS87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

574087:acear RS11260
gene id: 574087:acear_RS11260
uniprot id: D9QTY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

574087:acear RS11210
gene id: 574087:acear_RS11210
uniprot id: D9QTX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

574087:acear RS11355
gene id: 574087:acear_RS11355
uniprot id: D9QU02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

574087:acear RS12165
gene id: 574087:acear_RS12165
uniprot id: D9QQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

574087:acear RS04195
gene id: 574087:acear_RS04195
uniprot id: D9QVR4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

574087:acear RS07110
gene id: 574087:acear_RS07110
uniprot id: D9QQU4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS01635
gene id: 574087:acear_RS01635
uniprot id: D9QU55
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS06025
gene id: 574087:acear_RS06025
uniprot id: D9QQ85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

574087:acear RS05685
gene id: 574087:acear_RS05685
uniprot id: D9QQ15
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS07695
gene id: 574087:acear_RS07695
uniprot id: D9QR59
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS05005
gene id: 574087:acear_RS05005
uniprot id: D9QPN7
names: Similarity
messages: Belongs to the creatininase superfamily.

574087:acear RS10450
gene id: 574087:acear_RS10450
uniprot id: D9QT46
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

574087:acear RS03645
gene id: 574087:acear_RS03645
uniprot id: D9QVG8
names: Similarity
messages: Belongs to the FBPase class 2 family.

574087:acear RS09595
gene id: 574087:acear_RS09595
uniprot id: D9QS84
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

574087:acear RS00960
gene id: 574087:acear_RS00960
uniprot id: D9QTF3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

574087:acear RS04415
gene id: 574087:acear_RS04415
uniprot id: D9QVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

574087:acear RS06685
gene id: 574087:acear_RS06685
uniprot id: D9QQL7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

574087:acear RS00835
gene id: 574087:acear_RS00835
uniprot id: D9QT05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

574087:acear RS04545
gene id: 574087:acear_RS04545
uniprot id: D9QVX9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

574087:acear RS01180
gene id: 574087:acear_RS01180
uniprot id: D9QTJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

574087:acear RS03090
gene id: 574087:acear_RS03090
uniprot id: D9QV57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

574087:acear RS03840
gene id: 574087:acear_RS03840
uniprot id: D9QVK5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

574087:acear RS09730
gene id: 574087:acear_RS09730
uniprot id: D9QSD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08945
gene id: 574087:acear_RS08945
uniprot id: D9QRV3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

574087:acear RS01755
gene id: 574087:acear_RS01755
uniprot id: D9QU78
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

574087:acear RS10030
gene id: 574087:acear_RS10030
uniprot id: D9QSJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

574087:acear RS05635
gene id: 574087:acear_RS05635
uniprot id: D9QQ07
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

574087:acear RS02410
gene id: 574087:acear_RS02410
uniprot id: D9QUT0
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02105
gene id: 574087:acear_RS02105
uniprot id: D9QUE1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS03730
gene id: 574087:acear_RS03730
uniprot id: D9QVI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

574087:acear RS01490
gene id: 574087:acear_RS01490
uniprot id: D9QTQ5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

574087:acear RS10610
gene id: 574087:acear_RS10610
uniprot id: D9QT78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

574087:acear RS05625
gene id: 574087:acear_RS05625
uniprot id: D9QQ05
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

574087:acear RS01955
gene id: 574087:acear_RS01955
uniprot id: D9QUB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

574087:acear RS00895
gene id: 574087:acear_RS00895
uniprot id: D9QTE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

574087:acear RS05225
gene id: 574087:acear_RS05225
uniprot id: D9QPS9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

574087:acear RS07710
gene id: 574087:acear_RS07710
uniprot id: D9QR62
names: Cofactor
messages: Binds 1 zinc ion per subunit.

574087:acear RS02735
gene id: 574087:acear_RS02735
uniprot id: D9QUY9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

574087:acear RS01110
gene id: 574087:acear_RS01110
uniprot id: D9QTI3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

574087:acear RS08175
gene id: 574087:acear_RS08175
uniprot id: D9QRE8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

574087:acear RS04660
gene id: 574087:acear_RS04660
uniprot id: D9QPH1
names: Similarity
messages: Belongs to the YggT family.

574087:acear RS00360
gene id: 574087:acear_RS00360
uniprot id: D9QSS5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

574087:acear RS09095
gene id: 574087:acear_RS09095
uniprot id: D9QRY3
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS05340
gene id: 574087:acear_RS05340
uniprot id: D9QPV1
names: Similarity
messages: Belongs to the fabD family.

574087:acear RS06680
gene id: 574087:acear_RS06680
uniprot id: D9QQL6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

574087:acear RS10195
gene id: 574087:acear_RS10195
uniprot id: D9QSN4
names: Similarity
messages: Belongs to the DEAD box helicase family.

574087:acear RS11090
gene id: 574087:acear_RS11090
uniprot id: D9QTU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

574087:acear RS03290
gene id: 574087:acear_RS03290
uniprot id: D9QV95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

574087:acear RS03250
gene id: 574087:acear_RS03250
uniprot id: D9QV87
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

574087:acear RS06970
gene id: 574087:acear_RS06970
uniprot id: D9QQR4
names: Similarity
messages: Belongs to the ComB family.

574087:acear RS01175
gene id: 574087:acear_RS01175
uniprot id: D9QTJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

574087:acear RS07425
gene id: 574087:acear_RS07425
uniprot id: D9QR05
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

574087:acear RS03145
gene id: 574087:acear_RS03145
uniprot id: D9QV67
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS11785
gene id: 574087:acear_RS11785
uniprot id: D9QUK0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

574087:acear RS11055
gene id: 574087:acear_RS11055
uniprot id: D9QTU2
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02910
gene id: 574087:acear_RS02910
uniprot id: D9QV21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

574087:acear RS09020
gene id: 574087:acear_RS09020
uniprot id: D9QRW8
names: Similarity
messages: Belongs to the peptidase M24B family.

574087:acear RS05895
gene id: 574087:acear_RS05895
uniprot id: D9QQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

574087:acear RS09045
gene id: 574087:acear_RS09045
uniprot id: D9QRX3
names: Similarity
messages: Belongs to the bacterial secretin family.

574087:acear RS04715
gene id: 574087:acear_RS04715
uniprot id: D9QPI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

574087:acear RS03135
gene id: 574087:acear_RS03135
uniprot id: D9QV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

574087:acear RS01380
gene id: 574087:acear_RS01380
uniprot id: D9QTN4
names: Similarity
messages: Belongs to the bacterial flagellin family.

574087:acear RS05145
gene id: 574087:acear_RS05145
uniprot id: D9QPR4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

574087:acear RS11800
gene id: 574087:acear_RS11800
uniprot id: D9QUK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

574087:acear RS01065
gene id: 574087:acear_RS01065
uniprot id: D9QTH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

574087:acear RS03980
gene id: 574087:acear_RS03980
uniprot id: D9QVM1
names: Similarity
messages: Belongs to the transpeptidase family.

574087:acear RS02900
gene id: 574087:acear_RS02900
uniprot id: D9QV19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

574087:acear RS10215
gene id: 574087:acear_RS10215
uniprot id: D9QSN8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

574087:acear RS07380
gene id: 574087:acear_RS07380
uniprot id: D9QQZ6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

574087:acear RS05835
gene id: 574087:acear_RS05835
uniprot id: D9QQ47
names: Similarity
messages: Belongs to the thioredoxin family.

574087:acear RS06035
gene id: 574087:acear_RS06035
uniprot id: D9QQ87
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

574087:acear RS05150
gene id: 574087:acear_RS05150
uniprot id: D9QPR5
names: Similarity
messages: Belongs to the AOR/FOR family.

574087:acear RS08355
gene id: 574087:acear_RS08355
uniprot id: D9QRI4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

574087:acear RS03490
gene id: 574087:acear_RS03490
uniprot id: D9QVD7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS11820
gene id: 574087:acear_RS11820
uniprot id: D9QUK7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

574087:acear RS05800
gene id: 574087:acear_RS05800
uniprot id: D9QQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

574087:acear RS02540
gene id: 574087:acear_RS02540
uniprot id: D9QUV6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

574087:acear RS09550
gene id: 574087:acear_RS09550
uniprot id: D9QS75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

574087:acear RS01505
gene id: 574087:acear_RS01505
uniprot id: D9QTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

574087:acear RS08535
gene id: 574087:acear_RS08535
uniprot id: D9QRM0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

574087:acear RS10325
gene id: 574087:acear_RS10325
uniprot id: D9QT25
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

574087:acear RS00865
gene id: 574087:acear_RS00865
uniprot id: D9QTD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

574087:acear RS10225
gene id: 574087:acear_RS10225
uniprot id: D9QSP0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

574087:acear RS11450
gene id: 574087:acear_RS11450
uniprot id: D9QU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

574087:acear RS10140
gene id: 574087:acear_RS10140
uniprot id: D9QSL9
names: Similarity
messages: Belongs to the peptidase S8 family.

574087:acear RS10690
gene id: 574087:acear_RS10690
uniprot id: D9QT95
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

574087:acear RS10440
gene id: 574087:acear_RS10440
uniprot id: D9QT44
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

574087:acear RS02325
gene id: 574087:acear_RS02325
uniprot id: D9QUR2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

574087:acear RS05040
gene id: 574087:acear_RS05040
uniprot id: D9QPP4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

574087:acear RS08720
gene id: 574087:acear_RS08720
uniprot id: D9QRQ8
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS07665
gene id: 574087:acear_RS07665
uniprot id: D9QR53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

574087:acear RS04760
gene id: 574087:acear_RS04760
uniprot id: D9QPJ2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS11095
gene id: 574087:acear_RS11095
uniprot id: D9QTV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

574087:acear RS02675
gene id: 574087:acear_RS02675
uniprot id: D9QUY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

574087:acear RS07550
gene id: 574087:acear_RS07550
uniprot id: D9QR30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.

574087:acear RS11775
gene id: 574087:acear_RS11775
uniprot id: D9QUJ8
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

574087:acear RS11445
gene id: 574087:acear_RS11445
uniprot id: D9QU20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

574087:acear RS08680
gene id: 574087:acear_RS08680
uniprot id: D9QRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

574087:acear RS10860
gene id: 574087:acear_RS10860
uniprot id: D9QTC7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS07450
gene id: 574087:acear_RS07450
uniprot id: D9QR10
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

574087:acear RS06205
gene id: 574087:acear_RS06205
uniprot id: D9QQC2
names: Similarity
messages: Belongs to the RutC family.

574087:acear RS01160
gene id: 574087:acear_RS01160
uniprot id: D9QTJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

574087:acear RS05760
gene id: 574087:acear_RS05760
uniprot id: D9QQ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

574087:acear RS03575
gene id: 574087:acear_RS03575
uniprot id: D9QVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

574087:acear RS02290
gene id: 574087:acear_RS02290
uniprot id: D9QUQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

574087:acear RS06700
gene id: 574087:acear_RS06700
uniprot id: D9QQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

574087:acear RS04450
gene id: 574087:acear_RS04450
uniprot id: D9QVW0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

574087:acear RS10800
gene id: 574087:acear_RS10800
uniprot id: D9QTB6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

574087:acear RS06355
gene id: 574087:acear_RS06355
uniprot id: D9QQF1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS00315
gene id: 574087:acear_RS00315
uniprot id: D9QSR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS07640
gene id: 574087:acear_RS07640
uniprot id: D9QR48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS07935
gene id: 574087:acear_RS07935
uniprot id: D9QRA4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

574087:acear RS02385
gene id: 574087:acear_RS02385
uniprot id: D9QUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

574087:acear RS08280
gene id: 574087:acear_RS08280
uniprot id: D9QRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

574087:acear RS00135
gene id: 574087:acear_RS00135
uniprot id: D9QSB8
names: Similarity
messages: Belongs to the manganese catalase family.

574087:acear RS06950
gene id: 574087:acear_RS06950
uniprot id: D9QQQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

574087:acear RS09790
gene id: 574087:acear_RS09790
uniprot id: D9QSE9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS09130
gene id: 574087:acear_RS09130
uniprot id: D9QRZ0
names: Similarity
messages: Belongs to the EamA transporter family.

574087:acear RS11360
gene id: 574087:acear_RS11360
uniprot id: D9QU03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08830
gene id: 574087:acear_RS08830
uniprot id: D9QRT0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

574087:acear RS08740
gene id: 574087:acear_RS08740
uniprot id: D9QRR2
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02920
gene id: 574087:acear_RS02920
uniprot id: D9QV23
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

574087:acear RS07230
gene id: 574087:acear_RS07230
uniprot id: D9QQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

574087:acear RS00335
gene id: 574087:acear_RS00335
uniprot id: D9QSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

574087:acear RS02120
gene id: 574087:acear_RS02120
uniprot id: D9QUE4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

574087:acear RS08395
gene id: 574087:acear_RS08395
uniprot id: D9QRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

574087:acear RS06460
gene id: 574087:acear_RS06460
uniprot id: D9QQH2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS09165
gene id: 574087:acear_RS09165
uniprot id: D9QRZ7
names: Similarity
messages: Belongs to the DHPS family.

574087:acear RS02015
gene id: 574087:acear_RS02015
uniprot id: D9QUC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

574087:acear RS10880
gene id: 574087:acear_RS10880
uniprot id: D9QTR0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

574087:acear RS05275
gene id: 574087:acear_RS05275
uniprot id: D9QPT8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

574087:acear RS07715
gene id: 574087:acear_RS07715
uniprot id: D9QR63
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

574087:acear RS07000
gene id: 574087:acear_RS07000
uniprot id: D9QQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

574087:acear RS05170
gene id: 574087:acear_RS05170
uniprot id: D9QPR9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

574087:acear RS05585
gene id: 574087:acear_RS05585
uniprot id: D9QPZ7
names: Similarity
messages: Belongs to the thioredoxin family.

574087:acear RS08425
gene id: 574087:acear_RS08425
uniprot id: D9QRJ8
names: Similarity
messages: Belongs to the MotB family.

574087:acear RS00785
gene id: 574087:acear_RS00785
uniprot id: D9QSZ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

574087:acear RS05280
gene id: 574087:acear_RS05280
uniprot id: D9QPT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

574087:acear RS04050
gene id: 574087:acear_RS04050
uniprot id: D9QVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

574087:acear RS08135
gene id: 574087:acear_RS08135
uniprot id: D9QRE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

574087:acear RS09035
gene id: 574087:acear_RS09035
uniprot id: D9QRX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

574087:acear RS07270
gene id: 574087:acear_RS07270
uniprot id: D9QQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

574087:acear RS08920
gene id: 574087:acear_RS08920
uniprot id: D9QRU8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

574087:acear RS04560
gene id: 574087:acear_RS04560
uniprot id: D9QVY3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS10065
gene id: 574087:acear_RS10065
uniprot id: D9QSK1
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

574087:acear RS00485
gene id: 574087:acear_RS00485
uniprot id: D9QSV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08580
gene id: 574087:acear_RS08580
uniprot id: D9QRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

574087:acear RS02050
gene id: 574087:acear_RS02050
uniprot id: D9QUD3
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS11330
gene id: 574087:acear_RS11330
uniprot id: D9QTZ7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

574087:acear RS11700
gene id: 574087:acear_RS11700
uniprot id: D9QUI4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

574087:acear RS08115
gene id: 574087:acear_RS08115
uniprot id: D9QRD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

574087:acear RS06175
gene id: 574087:acear_RS06175
uniprot id: D9QQB6
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS07655
gene id: 574087:acear_RS07655
uniprot id: D9QR51
names: Similarity
messages: Belongs to the CinA family.

574087:acear RS02495
gene id: 574087:acear_RS02495
uniprot id: D9QUU7
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

574087:acear RS07245
gene id: 574087:acear_RS07245
uniprot id: D9QQW8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

574087:acear RS05755
gene id: 574087:acear_RS05755
uniprot id: D9QQ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

574087:acear RS01500
gene id: 574087:acear_RS01500
uniprot id: D9QTQ7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

574087:acear RS10180
gene id: 574087:acear_RS10180
uniprot id: D9QSN1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS04030
gene id: 574087:acear_RS04030
uniprot id: D9QVN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

574087:acear RS06960
gene id: 574087:acear_RS06960
uniprot id: D9QQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

574087:acear RS07650
gene id: 574087:acear_RS07650
uniprot id: D9QR50
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

574087:acear RS06125
gene id: 574087:acear_RS06125
uniprot id: D9QQA6
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02890
gene id: 574087:acear_RS02890
uniprot id: D9QV17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

574087:acear RS09830
gene id: 574087:acear_RS09830
uniprot id: D9QSF4
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS00940
gene id: 574087:acear_RS00940
uniprot id: D9QTE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

574087:acear RS08880
gene id: 574087:acear_RS08880
uniprot id: D9QRU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

574087:acear RS09995
gene id: 574087:acear_RS09995
uniprot id: D9QSI4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

574087:acear RS01125
gene id: 574087:acear_RS01125
uniprot id: D9QTI6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

574087:acear RS00660
gene id: 574087:acear_RS00660
uniprot id: D9QSY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS07560
gene id: 574087:acear_RS07560
uniprot id: D9QR32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

574087:acear RS10670
gene id: 574087:acear_RS10670
uniprot id: D9QT91
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08640
gene id: 574087:acear_RS08640
uniprot id: D9QRP1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

574087:acear RS05630
gene id: 574087:acear_RS05630
uniprot id: D9QQ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

574087:acear RS09160
gene id: 574087:acear_RS09160
uniprot id: D9QRZ6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

574087:acear RS02450
gene id: 574087:acear_RS02450
uniprot id: D9QUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

574087:acear RS02125
gene id: 574087:acear_RS02125
uniprot id: D9QUE5
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS08840
gene id: 574087:acear_RS08840
uniprot id: D9QRT2
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

574087:acear RS02960
gene id: 574087:acear_RS02960
uniprot id: D9QV31
names: Similarity
messages: Belongs to the Ahb/Nir family.

574087:acear RS04455
gene id: 574087:acear_RS04455
uniprot id: D9QVW1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

574087:acear RS01205
gene id: 574087:acear_RS01205
uniprot id: D9QTK2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS11990
gene id: 574087:acear_RS11990
uniprot id: D9QTN3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

574087:acear RS08140
gene id: 574087:acear_RS08140
uniprot id: D9QRE1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

574087:acear RS03735
gene id: 574087:acear_RS03735
uniprot id: D9QVI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

574087:acear RS01150
gene id: 574087:acear_RS01150
uniprot id: D9QTJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS02640
gene id: 574087:acear_RS02640
uniprot id: D9QUX6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS05500
gene id: 574087:acear_RS05500
uniprot id: D9QPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

574087:acear RS08370
gene id: 574087:acear_RS08370
uniprot id: D9QRI7
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

574087:acear RS04670
gene id: 574087:acear_RS04670
uniprot id: D9QPH3
names: Subcellular Location Annotation
messages: Cytoplasm

574087:acear RS02945
gene id: 574087:acear_RS02945
uniprot id: D9QV28
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

574087:acear RS00820
gene id: 574087:acear_RS00820
uniprot id: D9QT02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

574087:acear RS08785
gene id: 574087:acear_RS08785
uniprot id: D9QRS1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

574087:acear RS07210
gene id: 574087:acear_RS07210
uniprot id: D9QQW1
names: Similarity
messages: Belongs to the AAA ATPase family.

574087:acear RS08400
gene id: 574087:acear_RS08400
uniprot id: D9QRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

574087:acear RS01775
gene id: 574087:acear_RS01775
uniprot id: D9QU82
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

574087:acear RS00840
gene id: 574087:acear_RS00840
uniprot id: D9QTD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

574087:acear RS04145
gene id: 574087:acear_RS04145
uniprot id: D9QVQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

574087:acear RS00615
gene id: 574087:acear_RS00615
uniprot id: D9QSX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

574087:acear RS04040
gene id: 574087:acear_RS04040
uniprot id: D9QVN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

574087:acear RS08590
gene id: 574087:acear_RS08590
uniprot id: D9QRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

574087:acear RS11170
gene id: 574087:acear_RS11170
uniprot id: D9QTW5
names: Similarity
messages: Belongs to the Skp family.

574087:acear RS04120
gene id: 574087:acear_RS04120
uniprot id: D9QVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

574087:acear RS09190
gene id: 574087:acear_RS09190
uniprot id: D9QS02
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

574087:acear RS09380
gene id: 574087:acear_RS09380
uniprot id: D9QS40
names: Similarity
messages: Belongs to the glutamate synthase family.

574087:acear RS02150
gene id: 574087:acear_RS02150
uniprot id: D9QUN5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

574087:acear RS00920
gene id: 574087:acear_RS00920
uniprot id: D9QTE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

574087:acear RS05735
gene id: 574087:acear_RS05735
uniprot id: D9QQ25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

574087:acear RS01045
gene id: 574087:acear_RS01045
uniprot id: D9QTH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

574087:acear RS04390
gene id: 574087:acear_RS04390
uniprot id: D9QVU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

574087:acear RS11520
gene id: 574087:acear_RS11520
uniprot id: D9QUF5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

574087:acear RS08600
gene id: 574087:acear_RS08600
uniprot id: D9QRN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

574087:acear RS09645
gene id: 574087:acear_RS09645
uniprot id: D9QS94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

574087:acear RS10410
gene id: 574087:acear_RS10410
uniprot id: D9QT38
names: Similarity
messages: Belongs to the ThiD family.

574087:acear RS09015
gene id: 574087:acear_RS09015
uniprot id: D9QRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

574087:acear RS02505
gene id: 574087:acear_RS02505
uniprot id: D9QUU9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

574087:acear RS01390
gene id: 574087:acear_RS01390
uniprot id: D9QTN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

574087:acear RS06575
gene id: 574087:acear_RS06575
uniprot id: D9QQJ5
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

574087:acear RS09440
gene id: 574087:acear_RS09440
uniprot id: D9QS53
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

574087:acear RS10560
gene id: 574087:acear_RS10560
uniprot id: D9QT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

574087:acear RS02740
gene id: 574087:acear_RS02740
uniprot id: D9QUZ0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

574087:acear RS00510
gene id: 574087:acear_RS00510
uniprot id: D9QSV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

574087:acear RS02680
gene id: 574087:acear_RS02680
uniprot id: D9QUY4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

574087:acear RS07075
gene id: 574087:acear_RS07075
uniprot id: D9QQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

574087:acear RS07670
gene id: 574087:acear_RS07670
uniprot id: D9QR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

574087:acear RS10705
gene id: 574087:acear_RS10705
uniprot id: D9QT98
names: Similarity
messages: Belongs to the UDPGP type 2 family.

574087:acear RS02810
gene id: 574087:acear_RS02810
uniprot id: D9QV04
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

574087:acear RS01050
gene id: 574087:acear_RS01050
uniprot id: D9QTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

574087:acear RS11705
gene id: 574087:acear_RS11705
uniprot id: D9QUI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

574087:acear RS10495
gene id: 574087:acear_RS10495
uniprot id: D9QT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

574087:acear RS10270
gene id: 574087:acear_RS10270
uniprot id: D9QT12
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

574087:acear RS01325
gene id: 574087:acear_RS01325
uniprot id: D9QTM3
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS03995
gene id: 574087:acear_RS03995
uniprot id: D9QVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

574087:acear RS08700
gene id: 574087:acear_RS08700
uniprot id: D9QRQ3
names: Similarity
messages: Belongs to the acylphosphatase family.

574087:acear RS00685
gene id: 574087:acear_RS00685
uniprot id: D9QSY6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

574087:acear RS06295
gene id: 574087:acear_RS06295
uniprot id: D9QQE0
names: Similarity
messages: Belongs to the TPP enzyme family.

574087:acear RS11720
gene id: 574087:acear_RS11720
uniprot id: D9QUI7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

574087:acear RS04055
gene id: 574087:acear_RS04055
uniprot id: D9QVN6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

574087:acear RS06515
gene id: 574087:acear_RS06515
uniprot id: D9QQI3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

574087:acear RS06650
gene id: 574087:acear_RS06650
uniprot id: D9QQL0
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS05600
gene id: 574087:acear_RS05600
uniprot id: D9QQ00
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

574087:acear RS06335
gene id: 574087:acear_RS06335
uniprot id: D9QQE7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS06140
gene id: 574087:acear_RS06140
uniprot id: D9QQA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

574087:acear RS11930
gene id: 574087:acear_RS11930
uniprot id: D9QUM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

574087:acear RS06675
gene id: 574087:acear_RS06675
uniprot id: D9QQL5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

574087:acear RS03650
gene id: 574087:acear_RS03650
uniprot id: D9QVG9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

574087:acear RS01030
gene id: 574087:acear_RS01030
uniprot id: D9QTG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

574087:acear RS03035
gene id: 574087:acear_RS03035
uniprot id: D9QV46
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

574087:acear RS09850
gene id: 574087:acear_RS09850
uniprot id: D9QSF8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

574087:acear RS00010
gene id: 574087:acear_RS00010
uniprot id: D9QS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

574087:acear RS04270
gene id: 574087:acear_RS04270
uniprot id: D9QVS9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

574087:acear RS09565
gene id: 574087:acear_RS09565
uniprot id: D9QS78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

574087:acear RS04020
gene id: 574087:acear_RS04020
uniprot id: D9QVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

574087:acear RS04775
gene id: 574087:acear_RS04775
uniprot id: D9QPJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08090
gene id: 574087:acear_RS08090
uniprot id: D9QRD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

574087:acear RS11160
gene id: 574087:acear_RS11160
uniprot id: D9QTW3
names: Similarity
messages: Belongs to the Skp family.

574087:acear RS03065
gene id: 574087:acear_RS03065
uniprot id: D9QV52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

574087:acear RS02785
gene id: 574087:acear_RS02785
uniprot id: D9QUZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

574087:acear RS09410
gene id: 574087:acear_RS09410
uniprot id: D9QS47
names: Similarity
messages: Belongs to the asparagine synthetase family.

574087:acear RS05710
gene id: 574087:acear_RS05710
uniprot id: D9QQ20
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

574087:acear RS00565
gene id: 574087:acear_RS00565
uniprot id: D9QSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

574087:acear RS02455
gene id: 574087:acear_RS02455
uniprot id: D9QUT9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

574087:acear RS09040
gene id: 574087:acear_RS09040
uniprot id: D9QRX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

574087:acear RS11385
gene id: 574087:acear_RS11385
uniprot id: D9QU08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

574087:acear RS06615
gene id: 574087:acear_RS06615
uniprot id: D9QQK3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

574087:acear RS04320
gene id: 574087:acear_RS04320
uniprot id: D9QVT8
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

574087:acear RS01970
gene id: 574087:acear_RS01970
uniprot id: D9QUB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

574087:acear RS01875
gene id: 574087:acear_RS01875
uniprot id: D9QU99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

574087:acear RS06115
gene id: 574087:acear_RS06115
uniprot id: D9QQA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

574087:acear RS07530
gene id: 574087:acear_RS07530
uniprot id: D9QR26
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

574087:acear RS00650
gene id: 574087:acear_RS00650
uniprot id: D9QSX9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

574087:acear RS03000
gene id: 574087:acear_RS03000
uniprot id: D9QV39
names: Similarity
messages: Belongs to the UPF0758 family.

574087:acear RS00875
gene id: 574087:acear_RS00875
uniprot id: D9QTD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

574087:acear RS09535
gene id: 574087:acear_RS09535
uniprot id: D9QS72
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

574087:acear RS10155
gene id: 574087:acear_RS10155
uniprot id: D9QSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

574087:acear RS09955
gene id: 574087:acear_RS09955
uniprot id: D9QSH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS01770
gene id: 574087:acear_RS01770
uniprot id: D9QU81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

574087:acear RS11425
gene id: 574087:acear_RS11425
uniprot id: D9QU16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

574087:acear RS05995
gene id: 574087:acear_RS05995
uniprot id: D9QQ79
names: Similarity
messages: Belongs to the HypE family.

574087:acear RS03845
gene id: 574087:acear_RS03845
uniprot id: D9QVK6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

574087:acear RS01240
gene id: 574087:acear_RS01240
uniprot id: D9QTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

574087:acear RS00295
gene id: 574087:acear_RS00295
uniprot id: D9QSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

574087:acear RS04275
gene id: 574087:acear_RS04275
uniprot id: D9QVT0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

574087:acear RS10395
gene id: 574087:acear_RS10395
uniprot id: D9QT35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

574087:acear RS11245
gene id: 574087:acear_RS11245
uniprot id: D9QTY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

574087:acear RS02545
gene id: 574087:acear_RS02545
uniprot id: D9QUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

574087:acear RS10265
gene id: 574087:acear_RS10265
uniprot id: D9QT11
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

574087:acear RS11310
gene id: 574087:acear_RS11310
uniprot id: D9QTZ3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

574087:acear RS11880
gene id: 574087:acear_RS11880
uniprot id: D9QUL9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

574087:acear RS04745
gene id: 574087:acear_RS04745
uniprot id: D9QPI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

574087:acear RS04685
gene id: 574087:acear_RS04685
uniprot id: D9QPH6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

574087:acear RS05775
gene id: 574087:acear_RS05775
uniprot id: D9QQ35
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS08795
gene id: 574087:acear_RS08795
uniprot id: D9QRS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

574087:acear RS01155
gene id: 574087:acear_RS01155
uniprot id: D9QTJ2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

574087:acear RS07920
gene id: 574087:acear_RS07920
uniprot id: D9QRA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

574087:acear RS04990
gene id: 574087:acear_RS04990
uniprot id: D9QPN4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

574087:acear RS10555
gene id: 574087:acear_RS10555
uniprot id: D9QT67
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

574087:acear RS01020
gene id: 574087:acear_RS01020
uniprot id: D9QTG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

574087:acear RS10100
gene id: 574087:acear_RS10100
uniprot id: D9QSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

574087:acear RS03405
gene id: 574087:acear_RS03405
uniprot id: D9QVB9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

574087:acear RS10125
gene id: 574087:acear_RS10125
uniprot id: D9QSL6
names: Similarity
messages: Belongs to the hemerythrin family.

574087:acear RS05330
gene id: 574087:acear_RS05330
uniprot id: D9QPU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

574087:acear RS05235
gene id: 574087:acear_RS05235
uniprot id: D9QPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

574087:acear RS10400
gene id: 574087:acear_RS10400
uniprot id: D9QT36
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

574087:acear RS03815
gene id: 574087:acear_RS03815
uniprot id: D9QVK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

574087:acear RS09405
gene id: 574087:acear_RS09405
uniprot id: D9QS45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

574087:acear RS09145
gene id: 574087:acear_RS09145
uniprot id: D9QRZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

574087:acear RS11955
gene id: 574087:acear_RS11955
uniprot id: D9QUN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

574087:acear RS04490
gene id: 574087:acear_RS04490
uniprot id: D9QVW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

574087:acear RS03005
gene id: 574087:acear_RS03005
uniprot id: D9QV40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

574087:acear RS02365
gene id: 574087:acear_RS02365
uniprot id: D9QUS1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

574087:acear RS00975
gene id: 574087:acear_RS00975
uniprot id: D9QTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

574087:acear RS08925
gene id: 574087:acear_RS08925
uniprot id: D9QRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

574087:acear RS07495
gene id: 574087:acear_RS07495
uniprot id: D9QR19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

574087:acear RS05240
gene id: 574087:acear_RS05240
uniprot id: D9QPT1
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

574087:acear RS00075
gene id: 574087:acear_RS00075
uniprot id: D9QSA6
names: Similarity
messages: Belongs to the peptidase S49 family.

574087:acear RS05055
gene id: 574087:acear_RS05055
uniprot id: D9QPP7
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

574087:acear RS03675
gene id: 574087:acear_RS03675
uniprot id: D9QVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

574087:acear RS03865
gene id: 574087:acear_RS03865
uniprot id: D9QVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

574087:acear RS09395
gene id: 574087:acear_RS09395
uniprot id: D9QS43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

574087:acear RS10795
gene id: 574087:acear_RS10795
uniprot id: D9QTB5
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS01315
gene id: 574087:acear_RS01315
uniprot id: D9QTM1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS05300
gene id: 574087:acear_RS05300
uniprot id: D9QPU3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

574087:acear RS07995
gene id: 574087:acear_RS07995
uniprot id: D9QRB6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

574087:acear RS03695
gene id: 574087:acear_RS03695
uniprot id: D9QVH6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

574087:acear RS09870
gene id: 574087:acear_RS09870
uniprot id: D9QSG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

574087:acear RS05100
gene id: 574087:acear_RS05100
uniprot id: D9QPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

574087:acear RS03985
gene id: 574087:acear_RS03985
uniprot id: D9QVM2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS09715
gene id: 574087:acear_RS09715
uniprot id: D9QSD4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

574087:acear RS05450
gene id: 574087:acear_RS05450
uniprot id: D9QPX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

574087:acear RS10430
gene id: 574087:acear_RS10430
uniprot id: D9QT42
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

574087:acear RS05325
gene id: 574087:acear_RS05325
uniprot id: D9QPU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

574087:acear RS07740
gene id: 574087:acear_RS07740
uniprot id: D9QR67
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

574087:acear RS07410
gene id: 574087:acear_RS07410
uniprot id: D9QR02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

574087:acear RS10725
gene id: 574087:acear_RS10725
uniprot id: D9QTA2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

574087:acear RS06850
gene id: 574087:acear_RS06850
uniprot id: D9QQQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

574087:acear RS01580
gene id: 574087:acear_RS01580
uniprot id: D9QU44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

574087:acear RS08300
gene id: 574087:acear_RS08300
uniprot id: D9QRH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

574087:acear RS09260
gene id: 574087:acear_RS09260
uniprot id: D9QS16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

574087:acear RS04475
gene id: 574087:acear_RS04475
uniprot id: D9QVW5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

574087:acear RS00645
gene id: 574087:acear_RS00645
uniprot id: D9QSX8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

574087:acear RS11795
gene id: 574087:acear_RS11795
uniprot id: D9QUK2
names: Similarity
messages: Belongs to the GARS family.

574087:acear RS11265
gene id: 574087:acear_RS11265
uniprot id: D9QTY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

574087:acear RS03040
gene id: 574087:acear_RS03040
uniprot id: D9QV47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

574087:acear RS05350
gene id: 574087:acear_RS05350
uniprot id: D9QPV3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

574087:acear RS07025
gene id: 574087:acear_RS07025
uniprot id: D9QQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

574087:acear RS04755
gene id: 574087:acear_RS04755
uniprot id: D9QPJ1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

574087:acear RS08515
gene id: 574087:acear_RS08515
uniprot id: D9QRL6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

574087:acear RS10540
gene id: 574087:acear_RS10540
uniprot id: D9QT64
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

574087:acear RS03375
gene id: 574087:acear_RS03375
uniprot id: D9QVB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

574087:acear RS07825
gene id: 574087:acear_RS07825
uniprot id: D9QR83
names: Similarity
messages: Belongs to the AOR/FOR family.

574087:acear RS10040
gene id: 574087:acear_RS10040
uniprot id: D9QSJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS07865
gene id: 574087:acear_RS07865
uniprot id: D9QR91
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

574087:acear RS11835
gene id: 574087:acear_RS11835
uniprot id: D9QUL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

574087:acear RS04700
gene id: 574087:acear_RS04700
uniprot id: D9QPI0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

574087:acear RS00210
gene id: 574087:acear_RS00210
uniprot id: D9QSP6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

574087:acear RS04425
gene id: 574087:acear_RS04425
uniprot id: D9QVV5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

574087:acear RS05420
gene id: 574087:acear_RS05420
uniprot id: D9QPW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

574087:acear RS07890
gene id: 574087:acear_RS07890
uniprot id: D9QR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

574087:acear RS07300
gene id: 574087:acear_RS07300
uniprot id: D9QQY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

574087:acear RS08430
gene id: 574087:acear_RS08430
uniprot id: D9QRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

574087:acear RS11270
gene id: 574087:acear_RS11270
uniprot id: D9QTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

574087:acear RS00885
gene id: 574087:acear_RS00885
uniprot id: D9QTD8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

574087:acear RS05510
gene id: 574087:acear_RS05510
uniprot id: D9QPY4
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS10675
gene id: 574087:acear_RS10675
uniprot id: D9QT92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

574087:acear RS10765
gene id: 574087:acear_RS10765
uniprot id: D9QTA9
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02950
gene id: 574087:acear_RS02950
uniprot id: D9QV29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

574087:acear RS03240
gene id: 574087:acear_RS03240
uniprot id: D9QV85
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

574087:acear RS08320
gene id: 574087:acear_RS08320
uniprot id: D9QRH7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

574087:acear RS07370
gene id: 574087:acear_RS07370
uniprot id: D9QQZ4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

574087:acear RS09725
gene id: 574087:acear_RS09725
uniprot id: D9QSD6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

574087:acear RS09710
gene id: 574087:acear_RS09710
uniprot id: D9QSD3
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

574087:acear RS05535
gene id: 574087:acear_RS05535
uniprot id: D9QPY9
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS06200
gene id: 574087:acear_RS06200
uniprot id: D9QQC1
names: Similarity
messages: Belongs to the peptidase M20A family.

574087:acear RS11555
gene id: 574087:acear_RS11555
uniprot id: D9QUG0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

574087:acear RS09575
gene id: 574087:acear_RS09575
uniprot id: D9QS80
names: Similarity
messages: Belongs to the TrpC family.

574087:acear RS11805
gene id: 574087:acear_RS11805
uniprot id: D9QUK4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

574087:acear RS08415
gene id: 574087:acear_RS08415
uniprot id: D9QRJ6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

574087:acear RS09750
gene id: 574087:acear_RS09750
uniprot id: D9QSE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS04230
gene id: 574087:acear_RS04230
uniprot id: D9QVS1
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS10405
gene id: 574087:acear_RS10405
uniprot id: D9QT37
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS03720
gene id: 574087:acear_RS03720
uniprot id: D9QVI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

574087:acear RS05430
gene id: 574087:acear_RS05430
uniprot id: D9QPW8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

574087:acear RS11485
gene id: 574087:acear_RS11485
uniprot id: D9QU28
names: Similarity
messages: Belongs to the NAD synthetase family.

574087:acear RS04130
gene id: 574087:acear_RS04130
uniprot id: D9QVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

574087:acear RS04770
gene id: 574087:acear_RS04770
uniprot id: D9QPJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

574087:acear RS08000
gene id: 574087:acear_RS08000
uniprot id: D9QRB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

574087:acear RS06965
gene id: 574087:acear_RS06965
uniprot id: D9QQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

574087:acear RS03015
gene id: 574087:acear_RS03015
uniprot id: D9QV42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

574087:acear RS05875
gene id: 574087:acear_RS05875
uniprot id: D9QQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

574087:acear RS08500
gene id: 574087:acear_RS08500
uniprot id: D9QRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

574087:acear RS02930
gene id: 574087:acear_RS02930
uniprot id: D9QV25
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

574087:acear RS11490
gene id: 574087:acear_RS11490
uniprot id: D9QU29
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS08530
gene id: 574087:acear_RS08530
uniprot id: D9QRL9
names: Similarity
messages: Belongs to the DprA/Smf family.

574087:acear RS04495
gene id: 574087:acear_RS04495
uniprot id: D9QVW9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

574087:acear RS11950
gene id: 574087:acear_RS11950
uniprot id: D9QUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

574087:acear RS04140
gene id: 574087:acear_RS04140
uniprot id: D9QVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

574087:acear RS03210
gene id: 574087:acear_RS03210
uniprot id: D9QV79
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

574087:acear RS01170
gene id: 574087:acear_RS01170
uniprot id: D9QTJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

574087:acear RS03095
gene id: 574087:acear_RS03095
uniprot id: D9QV58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

574087:acear RS09500
gene id: 574087:acear_RS09500
uniprot id: D9QS65
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

574087:acear RS07190
gene id: 574087:acear_RS07190
uniprot id: D9QQV7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

574087:acear RS06185
gene id: 574087:acear_RS06185
uniprot id: D9QQB8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

574087:acear RS05725
gene id: 574087:acear_RS05725
uniprot id: D9QQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

574087:acear RS04100
gene id: 574087:acear_RS04100
uniprot id: D9QVP5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS03510
gene id: 574087:acear_RS03510
uniprot id: D9QVE0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

574087:acear RS02135
gene id: 574087:acear_RS02135
uniprot id: D9QUE7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS12000
gene id: 574087:acear_RS12000
uniprot id: D9QTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

574087:acear RS00455
gene id: 574087:acear_RS00455
uniprot id: D9QSU4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

574087:acear RS09530
gene id: 574087:acear_RS09530
uniprot id: D9QS71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08885
gene id: 574087:acear_RS08885
uniprot id: D9QRU1
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS08070
gene id: 574087:acear_RS08070
uniprot id: D9QRC7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

574087:acear RS04565
gene id: 574087:acear_RS04565
uniprot id: D9QVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

574087:acear RS05425
gene id: 574087:acear_RS05425
uniprot id: D9QPW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

574087:acear RS08595
gene id: 574087:acear_RS08595
uniprot id: D9QRN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

574087:acear RS07065
gene id: 574087:acear_RS07065
uniprot id: D9QQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

574087:acear RS05860
gene id: 574087:acear_RS05860
uniprot id: D9QQ52
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

574087:acear RS11650
gene id: 574087:acear_RS11650
uniprot id: D9QUH5
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS08485
gene id: 574087:acear_RS08485
uniprot id: D9QRL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

574087:acear RS08675
gene id: 574087:acear_RS08675
uniprot id: D9QRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

574087:acear RS05490
gene id: 574087:acear_RS05490
uniprot id: D9QPY0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

574087:acear RS07930
gene id: 574087:acear_RS07930
uniprot id: D9QRA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

574087:acear RS11155
gene id: 574087:acear_RS11155
uniprot id: D9QTW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

574087:acear RS11115
gene id: 574087:acear_RS11115
uniprot id: D9QTV4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

574087:acear RS05990
gene id: 574087:acear_RS05990
uniprot id: D9QQ78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

574087:acear RS01260
gene id: 574087:acear_RS01260
uniprot id: D9QTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

574087:acear RS00490
gene id: 574087:acear_RS00490
uniprot id: D9QSV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

574087:acear RS07430
gene id: 574087:acear_RS07430
uniprot id: D9QR06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusB family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

574087:acear RS11735
gene id: 574087:acear_RS11735
uniprot id: D9QUJ0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

574087:acear RS09350
gene id: 574087:acear_RS09350
uniprot id: D9QS35
names: Similarity
messages: Belongs to the histone deacetylase family.

574087:acear RS09840
gene id: 574087:acear_RS09840
uniprot id: D9QSF6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

574087:acear RS09755
gene id: 574087:acear_RS09755
uniprot id: D9QSE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS07400
gene id: 574087:acear_RS07400
uniprot id: D9QR00
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

574087:acear RS03760
gene id: 574087:acear_RS03760
uniprot id: D9QVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

574087:acear RS05840
gene id: 574087:acear_RS05840
uniprot id: D9QQ48
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

574087:acear RS12145
gene id: 574087:acear_RS12145
uniprot id: D9QQJ8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

574087:acear RS11305
gene id: 574087:acear_RS11305
uniprot id: D9QTZ2
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS05620
gene id: 574087:acear_RS05620
uniprot id: D9QQ04
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

574087:acear RS05615
gene id: 574087:acear_RS05615
uniprot id: D9QQ03
names: Similarity
messages: Belongs to the UPF0735 family.

574087:acear RS01405
gene id: 574087:acear_RS01405
uniprot id: D9QTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

574087:acear RS04630
gene id: 574087:acear_RS04630
uniprot id: D9QPG5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS08380
gene id: 574087:acear_RS08380
uniprot id: D9QRI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

574087:acear RS03555
gene id: 574087:acear_RS03555
uniprot id: D9QVE9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

574087:acear RS00430
gene id: 574087:acear_RS00430
uniprot id: D9QST9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

574087:acear RS06770
gene id: 574087:acear_RS06770
uniprot id: D9QQN5
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

574087:acear RS01890
gene id: 574087:acear_RS01890
uniprot id: D9QUA2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

574087:acear RS11280
gene id: 574087:acear_RS11280
uniprot id: D9QTY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

574087:acear RS09940
gene id: 574087:acear_RS09940
uniprot id: D9QSH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

574087:acear RS03620
gene id: 574087:acear_RS03620
uniprot id: D9QVG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

574087:acear RS04800
gene id: 574087:acear_RS04800
uniprot id: D9QPJ9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

574087:acear RS11285
gene id: 574087:acear_RS11285
uniprot id: D9QTY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

574087:acear RS04650
gene id: 574087:acear_RS04650
uniprot id: D9QPG9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

574087:acear RS09630
gene id: 574087:acear_RS09630
uniprot id: D9QS91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

574087:acear RS09545
gene id: 574087:acear_RS09545
uniprot id: D9QS74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

574087:acear RS03430
gene id: 574087:acear_RS03430
uniprot id: D9QVC4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

574087:acear RS03360
gene id: 574087:acear_RS03360
uniprot id: D9QVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

574087:acear RS11130
gene id: 574087:acear_RS11130
uniprot id: D9QTV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

574087:acear RS10290
gene id: 574087:acear_RS10290
uniprot id: D9QT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

574087:acear RS09635
gene id: 574087:acear_RS09635
uniprot id: D9QS92
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

574087:acear RS09700
gene id: 574087:acear_RS09700
uniprot id: D9QSD1
names: Subcellular Location Annotation
messages: Cytoplasm

574087:acear RS00005
gene id: 574087:acear_RS00005
uniprot id: D9QS97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

574087:acear RS09640
gene id: 574087:acear_RS09640
uniprot id: D9QS93
names: Similarity
messages: Belongs to the UPF0047 family.

574087:acear RS04435
gene id: 574087:acear_RS04435
uniprot id: D9QVV7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

574087:acear RS09390
gene id: 574087:acear_RS09390
uniprot id: D9QS42
names: Similarity
messages: Belongs to the P(II) protein family.

574087:acear RS03515
gene id: 574087:acear_RS03515
uniprot id: D9QVE1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

574087:acear RS02620
gene id: 574087:acear_RS02620
uniprot id: D9QUX2
names: Similarity
messages: Belongs to the class-I fumarase family.

574087:acear RS04185
gene id: 574087:acear_RS04185
uniprot id: D9QVR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

574087:acear RS02045
gene id: 574087:acear_RS02045
uniprot id: D9QUD2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS00775
gene id: 574087:acear_RS00775
uniprot id: D9QSZ3
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

574087:acear RS11760
gene id: 574087:acear_RS11760
uniprot id: D9QUJ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

574087:acear RS01480
gene id: 574087:acear_RS01480
uniprot id: D9QTQ3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

574087:acear RS08035
gene id: 574087:acear_RS08035
uniprot id: D9QRC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

574087:acear RS07500
gene id: 574087:acear_RS07500
uniprot id: D9QR20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

574087:acear RS09845
gene id: 574087:acear_RS09845
uniprot id: D9QSF7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

574087:acear RS00415
gene id: 574087:acear_RS00415
uniprot id: D9QST6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

574087:acear RS02370
gene id: 574087:acear_RS02370
uniprot id: D9QUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

574087:acear RS01550
gene id: 574087:acear_RS01550
uniprot id: D9QU38
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

574087:acear RS09760
gene id: 574087:acear_RS09760
uniprot id: D9QSE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS11365
gene id: 574087:acear_RS11365
uniprot id: D9QU04
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

574087:acear RS10570
gene id: 574087:acear_RS10570
uniprot id: D9QT70
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

574087:acear RS04260
gene id: 574087:acear_RS04260
uniprot id: D9QVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

574087:acear RS08775
gene id: 574087:acear_RS08775
uniprot id: D9QRR9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

574087:acear RS01980
gene id: 574087:acear_RS01980
uniprot id: D9QUB9
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS00035
gene id: 574087:acear_RS00035
uniprot id: D9QSA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

574087:acear RS00825
gene id: 574087:acear_RS00825
uniprot id: D9QT03
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

574087:acear RS07835
gene id: 574087:acear_RS07835
uniprot id: D9QR85
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

574087:acear RS00955
gene id: 574087:acear_RS00955
uniprot id: D9QTF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

574087:acear RS08255
gene id: 574087:acear_RS08255
uniprot id: D9QRG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

574087:acear RS04590
gene id: 574087:acear_RS04590
uniprot id: D9QVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

574087:acear RS02270
gene id: 574087:acear_RS02270
uniprot id: D9QUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

574087:acear RS09540
gene id: 574087:acear_RS09540
uniprot id: D9QS73
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS11215
gene id: 574087:acear_RS11215
uniprot id: D9QTX4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

574087:acear RS03850
gene id: 574087:acear_RS03850
uniprot id: D9QVK7
names: Similarity
messages: Belongs to the IMPACT family.

574087:acear RS08550
gene id: 574087:acear_RS08550
uniprot id: D9QRM3
names: Similarity
messages: Belongs to the UPF0145 family.

574087:acear RS00020
gene id: 574087:acear_RS00020
uniprot id: D9QSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

574087:acear RS01105
gene id: 574087:acear_RS01105
uniprot id: D9QTI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

574087:acear RS08745
gene id: 574087:acear_RS08745
uniprot id: D9QRR3
names: Similarity
messages: Belongs to the GerABKA family.

574087:acear RS01010
gene id: 574087:acear_RS01010
uniprot id: D9QTG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

574087:acear RS11770
gene id: 574087:acear_RS11770
uniprot id: D9QUJ7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

574087:acear RS07140
gene id: 574087:acear_RS07140
uniprot id: D9QPG5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS10525
gene id: 574087:acear_RS10525
uniprot id: D9QT61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

574087:acear RS11690
gene id: 574087:acear_RS11690
uniprot id: D9QUI2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

574087:acear RS00880
gene id: 574087:acear_RS00880
uniprot id: D9QTD7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

574087:acear RS10520
gene id: 574087:acear_RS10520
uniprot id: D9QT60
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

574087:acear RS07760
gene id: 574087:acear_RS07760
uniprot id: D9QR71
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

574087:acear RS09460
gene id: 574087:acear_RS09460
uniprot id: D9QS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

574087:acear RS05360
gene id: 574087:acear_RS05360
uniprot id: D9QPV5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

574087:acear RS02730
gene id: 574087:acear_RS02730
uniprot id: D9QUY8
names: Similarity
messages: Belongs to the peptidase S16 family.

574087:acear RS08505
gene id: 574087:acear_RS08505
uniprot id: D9QRL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

574087:acear RS08855
gene id: 574087:acear_RS08855
uniprot id: D9QRT5
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS01165
gene id: 574087:acear_RS01165
uniprot id: D9QTJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS02670
gene id: 574087:acear_RS02670
uniprot id: D9QUY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

574087:acear RS00095
gene id: 574087:acear_RS00095
uniprot id: D9QSB0
names: Similarity
messages: Belongs to the DtxR/MntR family.

574087:acear RS08510
gene id: 574087:acear_RS08510
uniprot id: D9QRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

574087:acear RS02215
gene id: 574087:acear_RS02215
uniprot id: D9QUP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

574087:acear RS06220
gene id: 574087:acear_RS06220
uniprot id: D9QQC5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

574087:acear RS05405
gene id: 574087:acear_RS05405
uniprot id: D9QPW3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

574087:acear RS10850
gene id: 574087:acear_RS10850
uniprot id: D9QTC5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

574087:acear RS02925
gene id: 574087:acear_RS02925
uniprot id: D9QV24
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

574087:acear RS07465
gene id: 574087:acear_RS07465
uniprot id: D9QR13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

574087:acear RS02800
gene id: 574087:acear_RS02800
uniprot id: D9QV02
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS07970
gene id: 574087:acear_RS07970
uniprot id: D9QRB1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

574087:acear RS02720
gene id: 574087:acear_RS02720
uniprot id: D9QUY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

574087:acear RS05730
gene id: 574087:acear_RS05730
uniprot id: D9QQ24
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

574087:acear RS07045
gene id: 574087:acear_RS07045
uniprot id: D9QQS9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

574087:acear RS10960
gene id: 574087:acear_RS10960
uniprot id: D9QTS3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

574087:acear RS11080
gene id: 574087:acear_RS11080
uniprot id: D9QTU7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

574087:acear RS00805
gene id: 574087:acear_RS00805
uniprot id: D9QSZ9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

574087:acear RS05085
gene id: 574087:acear_RS05085
uniprot id: D9QPQ3
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

574087:acear RS07030
gene id: 574087:acear_RS07030
uniprot id: D9QQS6
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS05080
gene id: 574087:acear_RS05080
uniprot id: D9QPQ2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

574087:acear RS03970
gene id: 574087:acear_RS03970
uniprot id: D9QVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

574087:acear RS08660
gene id: 574087:acear_RS08660
uniprot id: D9QRP5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

574087:acear RS01545
gene id: 574087:acear_RS01545
uniprot id: D9QU37
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

574087:acear RS09665
gene id: 574087:acear_RS09665
uniprot id: D9QSC6
names: Similarity
messages: Belongs to the Fur family.

574087:acear RS08520
gene id: 574087:acear_RS08520
uniprot id: D9QRL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

574087:acear RS06050
gene id: 574087:acear_RS06050
uniprot id: D9QQ90
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

574087:acear RS04905
gene id: 574087:acear_RS04905
uniprot id: D9QPL7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS09115
gene id: 574087:acear_RS09115
uniprot id: D9QRY7
names: Similarity
messages: Belongs to the GSP E family.

574087:acear RS08305
gene id: 574087:acear_RS08305
uniprot id: D9QRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

574087:acear RS02865
gene id: 574087:acear_RS02865
uniprot id: D9QV12
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

574087:acear RS08250
gene id: 574087:acear_RS08250
uniprot id: D9QRG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

574087:acear RS08125
gene id: 574087:acear_RS08125
uniprot id: D9QRD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

574087:acear RS02055
gene id: 574087:acear_RS02055
uniprot id: D9QUD4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

574087:acear RS11710
gene id: 574087:acear_RS11710
uniprot id: D9QUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

574087:acear RS02830
gene id: 574087:acear_RS02830
uniprot id: D9QV08
names: Similarity
messages: Belongs to the class-I fumarase family.

574087:acear RS04720
gene id: 574087:acear_RS04720
uniprot id: D9QPI4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

574087:acear RS03330
gene id: 574087:acear_RS03330
uniprot id: D9QVA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

574087:acear RS09200
gene id: 574087:acear_RS09200
uniprot id: D9QS04
names: Similarity
messages: Belongs to the UPF0251 family.

574087:acear RS07385
gene id: 574087:acear_RS07385
uniprot id: D9QQZ7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

574087:acear RS00240
gene id: 574087:acear_RS00240
uniprot id: D9QSQ2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

574087:acear RS08965
gene id: 574087:acear_RS08965
uniprot id: D9QRV7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

574087:acear RS01855
gene id: 574087:acear_RS01855
uniprot id: D9QU95
names: Similarity
messages: Belongs to the peptidase U62 family.

574087:acear RS08935
gene id: 574087:acear_RS08935
uniprot id: D9QRV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS00665
gene id: 574087:acear_RS00665
uniprot id: D9QSY2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

574087:acear RS06500
gene id: 574087:acear_RS06500
uniprot id: D9QQI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

574087:acear RS02430
gene id: 574087:acear_RS02430
uniprot id: D9QUT4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

574087:acear RS02625
gene id: 574087:acear_RS02625
uniprot id: D9QUX3
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS04895
gene id: 574087:acear_RS04895
uniprot id: D9QPL5
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS01035
gene id: 574087:acear_RS01035
uniprot id: D9QTG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

574087:acear RS02590
gene id: 574087:acear_RS02590
uniprot id: D9QUW6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS09090
gene id: 574087:acear_RS09090
uniprot id: D9QRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

574087:acear RS02955
gene id: 574087:acear_RS02955
uniprot id: D9QV30
names: Similarity
messages: Belongs to the Ahb/Nir family.

574087:acear RS05515
gene id: 574087:acear_RS05515
uniprot id: D9QPY5
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS00160
gene id: 574087:acear_RS00160
uniprot id: D9QSC3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

574087:acear RS03365
gene id: 574087:acear_RS03365
uniprot id: D9QVB0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

574087:acear RS05720
gene id: 574087:acear_RS05720
uniprot id: D9QQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

574087:acear RS10005
gene id: 574087:acear_RS10005
uniprot id: D9QSI6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

574087:acear RS01395
gene id: 574087:acear_RS01395
uniprot id: D9QTN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

574087:acear RS03750
gene id: 574087:acear_RS03750
uniprot id: D9QVI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

574087:acear RS05415
gene id: 574087:acear_RS05415
uniprot id: D9QPW5
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

574087:acear RS03755
gene id: 574087:acear_RS03755
uniprot id: D9QVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

574087:acear RS03020
gene id: 574087:acear_RS03020
uniprot id: D9QV43
names: Similarity
messages: Belongs to the transpeptidase family.

574087:acear RS10935
gene id: 574087:acear_RS10935
uniprot id: D9QTR8
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS04000
gene id: 574087:acear_RS04000
uniprot id: D9QVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

574087:acear RS08790
gene id: 574087:acear_RS08790
uniprot id: D9QRS2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

574087:acear RS02780
gene id: 574087:acear_RS02780
uniprot id: D9QUZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS01700
gene id: 574087:acear_RS01700
uniprot id: D9QU68
names: Similarity
messages: Belongs to the phosphohexose mutase family.

574087:acear RS07540
gene id: 574087:acear_RS07540
uniprot id: D9QR28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

574087:acear RS01015
gene id: 574087:acear_RS01015
uniprot id: D9QTG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

574087:acear RS10020
gene id: 574087:acear_RS10020
uniprot id: D9QSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

574087:acear RS11515
gene id: 574087:acear_RS11515
uniprot id: D9QUF4
names: Similarity
messages: Belongs to the thioredoxin family.

574087:acear RS07850
gene id: 574087:acear_RS07850
uniprot id: D9QR88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

574087:acear RS09585
gene id: 574087:acear_RS09585
uniprot id: D9QS82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

574087:acear RS08905
gene id: 574087:acear_RS08905
uniprot id: D9QRU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS00905
gene id: 574087:acear_RS00905
uniprot id: D9QTE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

574087:acear RS05315
gene id: 574087:acear_RS05315
uniprot id: D9QPU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

574087:acear RS03265
gene id: 574087:acear_RS03265
uniprot id: D9QV90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

574087:acear RS11275
gene id: 574087:acear_RS11275
uniprot id: D9QTY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

574087:acear RS06630
gene id: 574087:acear_RS06630
uniprot id: D9QQK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

574087:acear RS04655
gene id: 574087:acear_RS04655
uniprot id: D9QPH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

574087:acear RS08565
gene id: 574087:acear_RS08565
uniprot id: D9QRM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

574087:acear RS07035
gene id: 574087:acear_RS07035
uniprot id: D9QQS7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS05265
gene id: 574087:acear_RS05265
uniprot id: D9QPT6
names: Similarity
messages: Belongs to the peptidase S16 family.

574087:acear RS05010
gene id: 574087:acear_RS05010
uniprot id: D9QPN8
names: Similarity
messages: Belongs to the AOR/FOR family.

574087:acear RS10475
gene id: 574087:acear_RS10475
uniprot id: D9QT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

574087:acear RS03325
gene id: 574087:acear_RS03325
uniprot id: D9QVA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

574087:acear RS10580
gene id: 574087:acear_RS10580
uniprot id: D9QT72
names: Similarity
messages: Belongs to the GerABKA family.

574087:acear RS08310
gene id: 574087:acear_RS08310
uniprot id: D9QRH5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS09030
gene id: 574087:acear_RS09030
uniprot id: D9QRX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08690
gene id: 574087:acear_RS08690
uniprot id: D9QRQ1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

574087:acear RS07580
gene id: 574087:acear_RS07580
uniprot id: D9QR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

574087:acear RS04550
gene id: 574087:acear_RS04550
uniprot id: D9QVY0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS04025
gene id: 574087:acear_RS04025
uniprot id: D9QVN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS00620
gene id: 574087:acear_RS00620
uniprot id: D9QSX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

574087:acear RS08540
gene id: 574087:acear_RS08540
uniprot id: D9QRM1
names: Similarity
messages: Belongs to the UPF0102 family.

574087:acear RS00260
gene id: 574087:acear_RS00260
uniprot id: D9QSQ6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

574087:acear RS03530
gene id: 574087:acear_RS03530
uniprot id: D9QVE4
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

574087:acear RS07900
gene id: 574087:acear_RS07900
uniprot id: D9QR97
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08450
gene id: 574087:acear_RS08450
uniprot id: D9QRK3
names: Similarity
messages: Belongs to the FlgD family.

574087:acear RS01055
gene id: 574087:acear_RS01055
uniprot id: D9QTH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

574087:acear RS11790
gene id: 574087:acear_RS11790
uniprot id: D9QUK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS03030
gene id: 574087:acear_RS03030
uniprot id: D9QV45
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

574087:acear RS06180
gene id: 574087:acear_RS06180
uniprot id: D9QQB7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

574087:acear RS06640
gene id: 574087:acear_RS06640
uniprot id: D9QQK8
names: Similarity
messages: Belongs to the UPF0045 family.

574087:acear RS00945
gene id: 574087:acear_RS00945
uniprot id: D9QTF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

574087:acear RS09985
gene id: 574087:acear_RS09985
uniprot id: D9QSI2
names: Similarity
messages: Belongs to the GerABKA family.

574087:acear RS03990
gene id: 574087:acear_RS03990
uniprot id: D9QVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

574087:acear RS08060
gene id: 574087:acear_RS08060
uniprot id: D9QRC5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

574087:acear RS10680
gene id: 574087:acear_RS10680
uniprot id: D9QT93
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

574087:acear RS02820
gene id: 574087:acear_RS02820
uniprot id: D9QV06
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

574087:acear RS09125
gene id: 574087:acear_RS09125
uniprot id: D9QRY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS11235
gene id: 574087:acear_RS11235
uniprot id: D9QTX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS11135
gene id: 574087:acear_RS11135
uniprot id: D9QTV8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

574087:acear RS08805
gene id: 574087:acear_RS08805
uniprot id: D9QRS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

574087:acear RS05605
gene id: 574087:acear_RS05605
uniprot id: D9QQ01
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

574087:acear RS04915
gene id: 574087:acear_RS04915
uniprot id: D9QPL9
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

574087:acear RS01100
gene id: 574087:acear_RS01100
uniprot id: D9QTI1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS10905
gene id: 574087:acear_RS10905
uniprot id: D9QTR5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

574087:acear RS05660
gene id: 574087:acear_RS05660
uniprot id: D9QQ12
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

574087:acear RS04695
gene id: 574087:acear_RS04695
uniprot id: D9QPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

574087:acear RS05640
gene id: 574087:acear_RS05640
uniprot id: D9QQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

574087:acear RS01365
gene id: 574087:acear_RS01365
uniprot id: D9QTN1
names: Similarity
messages: Belongs to the FlgM family.

574087:acear RS11100
gene id: 574087:acear_RS11100
uniprot id: D9QTV1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

574087:acear RS06070
gene id: 574087:acear_RS06070
uniprot id: D9QQ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

574087:acear RS04110
gene id: 574087:acear_RS04110
uniprot id: D9QVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

574087:acear RS11935
gene id: 574087:acear_RS11935
uniprot id: D9QUM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS03340
gene id: 574087:acear_RS03340
uniprot id: D9QVA5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

574087:acear RS07910
gene id: 574087:acear_RS07910
uniprot id: D9QR99
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS10260
gene id: 574087:acear_RS10260
uniprot id: D9QT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

574087:acear RS04385
gene id: 574087:acear_RS04385
uniprot id: D9QVU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

574087:acear RS08495
gene id: 574087:acear_RS08495
uniprot id: D9QRL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

574087:acear RS02005
gene id: 574087:acear_RS02005
uniprot id: D9QUC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

574087:acear RS01805
gene id: 574087:acear_RS01805
uniprot id: D9QU88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

574087:acear RS00570
gene id: 574087:acear_RS00570
uniprot id: D9QSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

574087:acear RS01310
gene id: 574087:acear_RS01310
uniprot id: D9QTM0
names: Similarity
messages: Belongs to the bacterial secretin family.

574087:acear RS05440
gene id: 574087:acear_RS05440
uniprot id: D9QPX0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS11750
gene id: 574087:acear_RS11750
uniprot id: D9QUJ3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

574087:acear RS05130
gene id: 574087:acear_RS05130
uniprot id: D9QPR2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

574087:acear RS05525
gene id: 574087:acear_RS05525
uniprot id: D9QPY7
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS09990
gene id: 574087:acear_RS09990
uniprot id: D9QSI3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

574087:acear RS02030
gene id: 574087:acear_RS02030
uniprot id: D9QUC9
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS10585
gene id: 574087:acear_RS10585
uniprot id: D9QT73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

574087:acear RS11320
gene id: 574087:acear_RS11320
uniprot id: D9QTZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS10210
gene id: 574087:acear_RS10210
uniprot id: D9QSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

574087:acear RS02970
gene id: 574087:acear_RS02970
uniprot id: D9QV33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

574087:acear RS11255
gene id: 574087:acear_RS11255
uniprot id: D9QTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

574087:acear RS01075
gene id: 574087:acear_RS01075
uniprot id: D9QTH6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

574087:acear RS00530
gene id: 574087:acear_RS00530
uniprot id: D9QSV9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

574087:acear RS09150
gene id: 574087:acear_RS09150
uniprot id: D9QRZ4
names: Similarity
messages: Belongs to the Fur family.

574087:acear RS06365
gene id: 574087:acear_RS06365
uniprot id: D9QQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

574087:acear RS04600
gene id: 574087:acear_RS04600
uniprot id: D9QVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

574087:acear RS11250
gene id: 574087:acear_RS11250
uniprot id: D9QTY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

574087:acear RS10645
gene id: 574087:acear_RS10645
uniprot id: D9QT85
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

574087:acear RS11195
gene id: 574087:acear_RS11195
uniprot id: D9QTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

574087:acear RS06015
gene id: 574087:acear_RS06015
uniprot id: D9QQ83
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

574087:acear RS07950
gene id: 574087:acear_RS07950
uniprot id: D9QRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

574087:acear RS04750
gene id: 574087:acear_RS04750
uniprot id: D9QPJ0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

574087:acear RS03120
gene id: 574087:acear_RS03120
uniprot id: D9QV63
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

574087:acear RS03745
gene id: 574087:acear_RS03745
uniprot id: D9QVI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

574087:acear RS08915
gene id: 574087:acear_RS08915
uniprot id: D9QRU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

574087:acear RS03535
gene id: 574087:acear_RS03535
uniprot id: D9QVE5
names: Similarity
messages: Belongs to the HupF/HypC family.

574087:acear RS09825
gene id: 574087:acear_RS09825
uniprot id: D9QSF3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS11730
gene id: 574087:acear_RS11730
uniprot id: D9QUI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

574087:acear RS04540
gene id: 574087:acear_RS04540
uniprot id: D9QVX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

574087:acear RS11660
gene id: 574087:acear_RS11660
uniprot id: D9QUH7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

574087:acear RS06430
gene id: 574087:acear_RS06430
uniprot id: D9QQG6
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

574087:acear RS05780
gene id: 574087:acear_RS05780
uniprot id: D9QQ36
names: Similarity
messages: Belongs to the threonine synthase family.

574087:acear RS08130
gene id: 574087:acear_RS08130
uniprot id: D9QRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

574087:acear RS11420
gene id: 574087:acear_RS11420
uniprot id: D9QU15
names: Similarity
messages: Belongs to the glutamine synthetase family.

574087:acear RS08210
gene id: 574087:acear_RS08210
uniprot id: D9QRF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

574087:acear RS03800
gene id: 574087:acear_RS03800
uniprot id: D9QVJ7
names: Similarity
messages: Belongs to the RecJ family.

574087:acear RS11620
gene id: 574087:acear_RS11620
uniprot id: D9QUH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

574087:acear RS03410
gene id: 574087:acear_RS03410
uniprot id: D9QVC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

574087:acear RS11345
gene id: 574087:acear_RS11345
uniprot id: D9QU00
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

574087:acear RS03640
gene id: 574087:acear_RS03640
uniprot id: D9QVG7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

574087:acear RS06815
gene id: 574087:acear_RS06815
uniprot id: D9QQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

574087:acear RS02765
gene id: 574087:acear_RS02765
uniprot id: D9QUZ5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

574087:acear RS05030
gene id: 574087:acear_RS05030
uniprot id: D9QPP2
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

574087:acear RS09655
gene id: 574087:acear_RS09655
uniprot id: D9QS96
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

574087:acear RS01060
gene id: 574087:acear_RS01060
uniprot id: D9QTH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

574087:acear RS05495
gene id: 574087:acear_RS05495
uniprot id: D9QPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

574087:acear RS11560
gene id: 574087:acear_RS11560
uniprot id: D9QUG1
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS11325
gene id: 574087:acear_RS11325
uniprot id: D9QTZ6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

574087:acear RS05740
gene id: 574087:acear_RS05740
uniprot id: D9QQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

574087:acear RS07070
gene id: 574087:acear_RS07070
uniprot id: D9QQT4
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

574087:acear RS08095
gene id: 574087:acear_RS08095
uniprot id: D9QRD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

574087:acear RS00965
gene id: 574087:acear_RS00965
uniprot id: D9QTF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

574087:acear RS00680
gene id: 574087:acear_RS00680
uniprot id: D9QSY5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

574087:acear RS01765
gene id: 574087:acear_RS01765
uniprot id: D9QU80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS09435
gene id: 574087:acear_RS09435
uniprot id: D9QS52
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

574087:acear RS01330
gene id: 574087:acear_RS01330
uniprot id: D9QTM4
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS01195
gene id: 574087:acear_RS01195
uniprot id: D9QTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

574087:acear RS04485
gene id: 574087:acear_RS04485
uniprot id: D9QVW7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

574087:acear RS10055
gene id: 574087:acear_RS10055
uniprot id: D9QSJ8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

574087:acear RS10310
gene id: 574087:acear_RS10310
uniprot id: D9QT22
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

574087:acear RS00765
gene id: 574087:acear_RS00765
uniprot id: D9QSZ1
names: Similarity
messages: Belongs to the CtsR family.

574087:acear RS01040
gene id: 574087:acear_RS01040
uniprot id: D9QTG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

574087:acear RS08490
gene id: 574087:acear_RS08490
uniprot id: D9QRL1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

574087:acear RS08235
gene id: 574087:acear_RS08235
uniprot id: D9QRG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

574087:acear RS08410
gene id: 574087:acear_RS08410
uniprot id: D9QRJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

574087:acear RS03540
gene id: 574087:acear_RS03540
uniprot id: D9QVE6
names: Similarity
messages: Belongs to the HypD family.

574087:acear RS11315
gene id: 574087:acear_RS11315
uniprot id: D9QTZ4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

574087:acear RS07955
gene id: 574087:acear_RS07955
uniprot id: D9QRA8
names: Similarity
messages: Belongs to the GerABKA family.

574087:acear RS11125
gene id: 574087:acear_RS11125
uniprot id: D9QTV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

574087:acear RS00935
gene id: 574087:acear_RS00935
uniprot id: D9QTE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

574087:acear RS06135
gene id: 574087:acear_RS06135
uniprot id: D9QQA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

574087:acear RS09120
gene id: 574087:acear_RS09120
uniprot id: D9QRY8
names: Similarity
messages: Belongs to the GSP E family.

574087:acear RS04580
gene id: 574087:acear_RS04580
uniprot id: D9QVY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

574087:acear RS07525
gene id: 574087:acear_RS07525
uniprot id: D9QR25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

574087:acear RS09960
gene id: 574087:acear_RS09960
uniprot id: D9QSI0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS00970
gene id: 574087:acear_RS00970
uniprot id: D9QTF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

574087:acear RS04820
gene id: 574087:acear_RS04820
uniprot id: D9QPK2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS03425
gene id: 574087:acear_RS03425
uniprot id: D9QVC3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

574087:acear RS07905
gene id: 574087:acear_RS07905
uniprot id: D9QR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

574087:acear RS00790
gene id: 574087:acear_RS00790
uniprot id: D9QSZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

574087:acear RS06105
gene id: 574087:acear_RS06105
uniprot id: D9QQA1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

574087:acear RS01655
gene id: 574087:acear_RS01655
uniprot id: D9QU59
names: Similarity
messages: Belongs to the phosphohexose mutase family.

574087:acear RS01070
gene id: 574087:acear_RS01070
uniprot id: D9QTH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

574087:acear RS07575
gene id: 574087:acear_RS07575
uniprot id: D9QR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

574087:acear RS05610
gene id: 574087:acear_RS05610
uniprot id: D9QQ02
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

574087:acear RS05075
gene id: 574087:acear_RS05075
uniprot id: D9QPQ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS09175
gene id: 574087:acear_RS09175
uniprot id: D9QRZ9
names: Similarity
messages: Belongs to the peptidase A31 family.

574087:acear RS09925
gene id: 574087:acear_RS09925
uniprot id: D9QSH3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

574087:acear RS09625
gene id: 574087:acear_RS09625
uniprot id: D9QS90
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

574087:acear RS08695
gene id: 574087:acear_RS08695
uniprot id: D9QRQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

574087:acear RS10460
gene id: 574087:acear_RS10460
uniprot id: D9QT48
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

574087:acear RS05260
gene id: 574087:acear_RS05260
uniprot id: D9QPT5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08685
gene id: 574087:acear_RS08685
uniprot id: D9QRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

574087:acear RS08375
gene id: 574087:acear_RS08375
uniprot id: D9QRI8
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

574087:acear RS01080
gene id: 574087:acear_RS01080
uniprot id: D9QTH7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

574087:acear RS09480
gene id: 574087:acear_RS09480
uniprot id: D9QS61
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

574087:acear RS08955
gene id: 574087:acear_RS08955
uniprot id: D9QRV5
names: Similarity
messages: Belongs to the asp23 family.

574087:acear RS08385
gene id: 574087:acear_RS08385
uniprot id: D9QRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

574087:acear RS04005
gene id: 574087:acear_RS04005
uniprot id: D9QVM6
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS03150
gene id: 574087:acear_RS03150
uniprot id: D9QV68
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

574087:acear RS07680
gene id: 574087:acear_RS07680
uniprot id: D9QR56
names: Similarity
messages: Belongs to the AOR/FOR family.

574087:acear RS10875
gene id: 574087:acear_RS10875
uniprot id: D9QTQ9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

574087:acear RS07965
gene id: 574087:acear_RS07965
uniprot id: D9QRB0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

574087:acear RS01750
gene id: 574087:acear_RS01750
uniprot id: D9QU77
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

574087:acear RS07275
gene id: 574087:acear_RS07275
uniprot id: D9QQX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

574087:acear RS05745
gene id: 574087:acear_RS05745
uniprot id: D9QQ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

574087:acear RS02225
gene id: 574087:acear_RS02225
uniprot id: D9QUP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

574087:acear RS00640
gene id: 574087:acear_RS00640
uniprot id: D9QSX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

574087:acear RS07115
gene id: 574087:acear_RS07115
uniprot id: D9QQU5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS02035
gene id: 574087:acear_RS02035
uniprot id: D9QUD0
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02595
gene id: 574087:acear_RS02595
uniprot id: D9QUW7
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

574087:acear RS00990
gene id: 574087:acear_RS00990
uniprot id: D9QTF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

574087:acear RS02230
gene id: 574087:acear_RS02230
uniprot id: D9QUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

574087:acear RS07485
gene id: 574087:acear_RS07485
uniprot id: D9QR17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

574087:acear RS09275
gene id: 574087:acear_RS09275
uniprot id: D9QS19
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

574087:acear RS04765
gene id: 574087:acear_RS04765
uniprot id: D9QPJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

574087:acear RS02260
gene id: 574087:acear_RS02260
uniprot id: D9QUQ0
names: Similarity
messages: Belongs to the UPF0297 family.

574087:acear RS01585
gene id: 574087:acear_RS01585
uniprot id: D9QU45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

574087:acear RS00800
gene id: 574087:acear_RS00800
uniprot id: D9QSZ8
names: Similarity
messages: Belongs to the ycf81 family.

574087:acear RS09930
gene id: 574087:acear_RS09930
uniprot id: D9QSH4
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS10595
gene id: 574087:acear_RS10595
uniprot id: D9QT75
names: Similarity
messages: Belongs to the UPF0237 family.

574087:acear RS07390
gene id: 574087:acear_RS07390
uniprot id: D9QQZ8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

574087:acear RS05705
gene id: 574087:acear_RS05705
uniprot id: D9QQ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

574087:acear RS05985
gene id: 574087:acear_RS05985
uniprot id: D9QQ77
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

574087:acear RS01920
gene id: 574087:acear_RS01920
uniprot id: D9QUA8
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

574087:acear RS02940
gene id: 574087:acear_RS02940
uniprot id: D9QV27
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

574087:acear RS05750
gene id: 574087:acear_RS05750
uniprot id: D9QQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

574087:acear RS00520
gene id: 574087:acear_RS00520
uniprot id: D9QSV7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS06325
gene id: 574087:acear_RS06325
uniprot id: D9QQE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

574087:acear RS02905
gene id: 574087:acear_RS02905
uniprot id: D9QV20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

574087:acear RS07280
gene id: 574087:acear_RS07280
uniprot id: D9QQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

574087:acear RS04015
gene id: 574087:acear_RS04015
uniprot id: D9QVM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

574087:acear RS03775
gene id: 574087:acear_RS03775
uniprot id: D9QVJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

574087:acear RS10550
gene id: 574087:acear_RS10550
uniprot id: D9QT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

574087:acear RS01760
gene id: 574087:acear_RS01760
uniprot id: D9QU79
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

574087:acear RS11925
gene id: 574087:acear_RS11925
uniprot id: D9QUM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

574087:acear RS07520
gene id: 574087:acear_RS07520
uniprot id: D9QR24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

574087:acear RS06045
gene id: 574087:acear_RS06045
uniprot id: D9QQ89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

574087:acear RS04480
gene id: 574087:acear_RS04480
uniprot id: D9QVW6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

574087:acear RS07330
gene id: 574087:acear_RS07330
uniprot id: D9QQY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

574087:acear RS07735
gene id: 574087:acear_RS07735
uniprot id: D9QR66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

574087:acear RS03670
gene id: 574087:acear_RS03670
uniprot id: D9QVH3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

574087:acear RS01520
gene id: 574087:acear_RS01520
uniprot id: D9QU32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

574087:acear RS10895
gene id: 574087:acear_RS10895
uniprot id: D9QTR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

574087:acear RS06975
gene id: 574087:acear_RS06975
uniprot id: D9QQR5
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

574087:acear RS00445
gene id: 574087:acear_RS00445
uniprot id: D9QSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

574087:acear RS06620
gene id: 574087:acear_RS06620
uniprot id: D9QQK4
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02010
gene id: 574087:acear_RS02010
uniprot id: D9QUC5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

574087:acear RS01880
gene id: 574087:acear_RS01880
uniprot id: D9QUA0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

574087:acear RS06435
gene id: 574087:acear_RS06435
uniprot id: D9QQG7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

574087:acear RS08295
gene id: 574087:acear_RS08295
uniprot id: D9QRH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

574087:acear RS01740
gene id: 574087:acear_RS01740
uniprot id: D9QU76
names: Similarity
messages: Belongs to the sigma-54 factor family.

574087:acear RS07455
gene id: 574087:acear_RS07455
uniprot id: D9QR11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

574087:acear RS05270
gene id: 574087:acear_RS05270
uniprot id: D9QPT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS04575
gene id: 574087:acear_RS04575
uniprot id: D9QVY6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS03220
gene id: 574087:acear_RS03220
uniprot id: D9QV81
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

574087:acear RS00830
gene id: 574087:acear_RS00830
uniprot id: D9QT04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

574087:acear RS07545
gene id: 574087:acear_RS07545
uniprot id: D9QR29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

574087:acear RS05305
gene id: 574087:acear_RS05305
uniprot id: D9QPU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

574087:acear RS04315
gene id: 574087:acear_RS04315
uniprot id: D9QVT7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS11290
gene id: 574087:acear_RS11290
uniprot id: D9QTY9
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS00985
gene id: 574087:acear_RS00985
uniprot id: D9QTF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

574087:acear RS10455
gene id: 574087:acear_RS10455
uniprot id: D9QT47
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

574087:acear RS00355
gene id: 574087:acear_RS00355
uniprot id: D9QSS4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

574087:acear RS01690
gene id: 574087:acear_RS01690
uniprot id: D9QU66
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

574087:acear RS11900
gene id: 574087:acear_RS11900
uniprot id: D9QUM2
names: Similarity
messages: Belongs to the ParB family.

574087:acear RS03595
gene id: 574087:acear_RS03595
uniprot id: D9QVF7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02060
gene id: 574087:acear_RS02060
uniprot id: D9QUD5
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

574087:acear RS10205
gene id: 574087:acear_RS10205
uniprot id: D9QSN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

574087:acear RS07915
gene id: 574087:acear_RS07915
uniprot id: D9QRA0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

574087:acear RS01640
gene id: 574087:acear_RS01640
uniprot id: D9QU56
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

574087:acear RS01600
gene id: 574087:acear_RS01600
uniprot id: D9QU48
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

574087:acear RS02525
gene id: 574087:acear_RS02525
uniprot id: D9QUV3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

574087:acear RS07095
gene id: 574087:acear_RS07095
uniprot id: D9QQU1
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS10735
gene id: 574087:acear_RS10735
uniprot id: D9QTA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

574087:acear RS00205
gene id: 574087:acear_RS00205
uniprot id: D9QSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

574087:acear RS11200
gene id: 574087:acear_RS11200
uniprot id: D9QTX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

574087:acear RS03080
gene id: 574087:acear_RS03080
uniprot id: D9QV55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

574087:acear RS07505
gene id: 574087:acear_RS07505
uniprot id: D9QR21
names: Similarity
messages: Belongs to the RemA family.

574087:acear RS08900
gene id: 574087:acear_RS08900
uniprot id: D9QRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

574087:acear RS03235
gene id: 574087:acear_RS03235
uniprot id: D9QV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

574087:acear RS11380
gene id: 574087:acear_RS11380
uniprot id: D9QU07
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS08005
gene id: 574087:acear_RS08005
uniprot id: D9QRB8
names: Subcellular Location Annotation
messages: Cytoplasm

574087:acear RS08480
gene id: 574087:acear_RS08480
uniprot id: D9QRK9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

574087:acear RS07960
gene id: 574087:acear_RS07960
uniprot id: D9QRA9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

574087:acear RS05445
gene id: 574087:acear_RS05445
uniprot id: D9QPX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

574087:acear RS00915
gene id: 574087:acear_RS00915
uniprot id: D9QTE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

574087:acear RS10695
gene id: 574087:acear_RS10695
uniprot id: D9QT96
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

574087:acear RS11845
gene id: 574087:acear_RS11845
uniprot id: D9QUL2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

574087:acear RS02915
gene id: 574087:acear_RS02915
uniprot id: D9QV22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

574087:acear RS04250
gene id: 574087:acear_RS04250
uniprot id: D9QVS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

574087:acear RS03770
gene id: 574087:acear_RS03770
uniprot id: D9QVJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

574087:acear RS05365
gene id: 574087:acear_RS05365
uniprot id: D9QPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

574087:acear RS04975
gene id: 574087:acear_RS04975
uniprot id: D9QPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

574087:acear RS10530
gene id: 574087:acear_RS10530
uniprot id: D9QT62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

574087:acear RS00330
gene id: 574087:acear_RS00330
uniprot id: D9QSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

574087:acear RS06785
gene id: 574087:acear_RS06785
uniprot id: D9QQN8
names: Similarity
messages: Belongs to the TPP enzyme family.

574087:acear RS12100
gene id: 574087:acear_RS12100
uniprot id: D9QVV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

574087:acear RS07855
gene id: 574087:acear_RS07855
uniprot id: D9QR89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

574087:acear RS07460
gene id: 574087:acear_RS07460
uniprot id: D9QR12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

574087:acear RS11605
gene id: 574087:acear_RS11605
uniprot id: D9QUG8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

574087:acear RS04690
gene id: 574087:acear_RS04690
uniprot id: D9QPH8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

574087:acear RS08225
gene id: 574087:acear_RS08225
uniprot id: D9QRF8
names: Similarity
messages: Belongs to the ribF family.

574087:acear RS00890
gene id: 574087:acear_RS00890
uniprot id: D9QTD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

574087:acear RS11740
gene id: 574087:acear_RS11740
uniprot id: D9QUJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS06040
gene id: 574087:acear_RS06040
uniprot id: D9QQ88
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

574087:acear RS05865
gene id: 574087:acear_RS05865
uniprot id: D9QQ53
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

574087:acear RS02115
gene id: 574087:acear_RS02115
uniprot id: D9QUE3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

574087:acear RS04105
gene id: 574087:acear_RS04105
uniprot id: D9QVP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

574087:acear RS02750
gene id: 574087:acear_RS02750
uniprot id: D9QUZ2
names: Similarity
messages: Belongs to the UbiD family.

574087:acear RS08620
gene id: 574087:acear_RS08620
uniprot id: D9QRN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

574087:acear RS04885
gene id: 574087:acear_RS04885
uniprot id: D9QPL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

574087:acear RS08470
gene id: 574087:acear_RS08470
uniprot id: D9QRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

574087:acear RS06635
gene id: 574087:acear_RS06635
uniprot id: D9QQK7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

574087:acear RS10575
gene id: 574087:acear_RS10575
uniprot id: D9QT71
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

574087:acear RS02895
gene id: 574087:acear_RS02895
uniprot id: D9QV18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

574087:acear RS01850
gene id: 574087:acear_RS01850
uniprot id: D9QU94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

574087:acear RS10445
gene id: 574087:acear_RS10445
uniprot id: D9QT45
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

574087:acear RS07515
gene id: 574087:acear_RS07515
uniprot id: D9QR23
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

574087:acear RS00655
gene id: 574087:acear_RS00655
uniprot id: D9QSY0
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS04170
gene id: 574087:acear_RS04170
uniprot id: D9QVQ9
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS04160
gene id: 574087:acear_RS04160
uniprot id: D9QVQ7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS08610
gene id: 574087:acear_RS08610
uniprot id: D9QRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

574087:acear RS05400
gene id: 574087:acear_RS05400
uniprot id: D9QPW2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

574087:acear RS10590
gene id: 574087:acear_RS10590
uniprot id: D9QT74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

574087:acear RS03805
gene id: 574087:acear_RS03805
uniprot id: D9QVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

574087:acear RS01090
gene id: 574087:acear_RS01090
uniprot id: D9QTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

574087:acear RS06225
gene id: 574087:acear_RS06225
uniprot id: D9QQC6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

574087:acear RS04930
gene id: 574087:acear_RS04930
uniprot id: D9QPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

574087:acear RS00165
gene id: 574087:acear_RS00165
uniprot id: D9QSC4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS06030
gene id: 574087:acear_RS06030
uniprot id: D9QQ86
names: Similarity
messages: Belongs to the UPF0342 family.

574087:acear RS02000
gene id: 574087:acear_RS02000
uniprot id: D9QUC3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

574087:acear RS09235
gene id: 574087:acear_RS09235
uniprot id: D9QS11
names: Similarity
messages: Belongs to the Fur family.

574087:acear RS07290
gene id: 574087:acear_RS07290
uniprot id: D9QQX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS02155
gene id: 574087:acear_RS02155
uniprot id: D9QUN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

574087:acear RS02405
gene id: 574087:acear_RS02405
uniprot id: D9QUS9
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS09325
gene id: 574087:acear_RS09325
uniprot id: D9QS30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

574087:acear RS01000
gene id: 574087:acear_RS01000
uniprot id: D9QTG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

574087:acear RS05395
gene id: 574087:acear_RS05395
uniprot id: D9QPW1
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

574087:acear RS01095
gene id: 574087:acear_RS01095
uniprot id: D9QTI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

574087:acear RS08215
gene id: 574087:acear_RS08215
uniprot id: D9QRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

574087:acear RS00810
gene id: 574087:acear_RS00810
uniprot id: D9QT00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS02645
gene id: 574087:acear_RS02645
uniprot id: D9QUX7
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

574087:acear RS04725
gene id: 574087:acear_RS04725
uniprot id: D9QPI5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

574087:acear RS02390
gene id: 574087:acear_RS02390
uniprot id: D9QUS6
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

574087:acear RS10535
gene id: 574087:acear_RS10535
uniprot id: D9QT63
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

574087:acear RS00630
gene id: 574087:acear_RS00630
uniprot id: D9QSX5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

574087:acear RS05345
gene id: 574087:acear_RS05345
uniprot id: D9QPV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

574087:acear RS09400
gene id: 574087:acear_RS09400
uniprot id: D9QS44
names: Similarity
messages: Belongs to the glutamine synthetase family.

574087:acear RS01215
gene id: 574087:acear_RS01215
uniprot id: D9QTK4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

574087:acear RS07310
gene id: 574087:acear_RS07310
uniprot id: D9QQY2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

574087:acear RS10165
gene id: 574087:acear_RS10165
uniprot id: D9QSM7
names: Similarity
messages: Belongs to the peptidase S8 family.

574087:acear RS05375
gene id: 574087:acear_RS05375
uniprot id: D9QPV7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS08240
gene id: 574087:acear_RS08240
uniprot id: D9QRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

574087:acear RS10280
gene id: 574087:acear_RS10280
uniprot id: D9QT14
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

574087:acear RS01810
gene id: 574087:acear_RS01810
uniprot id: D9QU89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

574087:acear RS01860
gene id: 574087:acear_RS01860
uniprot id: D9QU96
names: Similarity
messages: Belongs to the peptidase U62 family.

574087:acear RS00870
gene id: 574087:acear_RS00870
uniprot id: D9QTD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

574087:acear RS02445
gene id: 574087:acear_RS02445
uniprot id: D9QUT7
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS06860
gene id: 574087:acear_RS06860
uniprot id: D9QQQ3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

574087:acear RS08605
gene id: 574087:acear_RS08605
uniprot id: D9QRN4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

574087:acear RS11085
gene id: 574087:acear_RS11085
uniprot id: D9QTU8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

574087:acear RS04045
gene id: 574087:acear_RS04045
uniprot id: D9QVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

574087:acear RS06120
gene id: 574087:acear_RS06120
uniprot id: D9QQA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

574087:acear RS08220
gene id: 574087:acear_RS08220
uniprot id: D9QRF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

574087:acear RS02285
gene id: 574087:acear_RS02285
uniprot id: D9QUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

574087:acear RS00950
gene id: 574087:acear_RS00950
uniprot id: D9QTF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

574087:acear RS11395
gene id: 574087:acear_RS11395
uniprot id: D9QU10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS10720
gene id: 574087:acear_RS10720
uniprot id: D9QTA1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

574087:acear RS11590
gene id: 574087:acear_RS11590
uniprot id: D9QUG5
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

574087:acear RS08290
gene id: 574087:acear_RS08290
uniprot id: D9QRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

574087:acear RS00910
gene id: 574087:acear_RS00910
uniprot id: D9QTE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

574087:acear RS02975
gene id: 574087:acear_RS02975
uniprot id: D9QV34
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

574087:acear RS08570
gene id: 574087:acear_RS08570
uniprot id: D9QRM7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

574087:acear RS02725
gene id: 574087:acear_RS02725
uniprot id: D9QUY7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

574087:acear RS04010
gene id: 574087:acear_RS04010
uniprot id: D9QVM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS04735
gene id: 574087:acear_RS04735
uniprot id: D9QPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

574087:acear RS03255
gene id: 574087:acear_RS03255
uniprot id: D9QV88
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

574087:acear RS06350
gene id: 574087:acear_RS06350
uniprot id: D9QQF0
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS01905
gene id: 574087:acear_RS01905
uniprot id: D9QUA5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS12090
gene id: 574087:acear_RS12090
uniprot id: D9QVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

574087:acear RS04240
gene id: 574087:acear_RS04240
uniprot id: D9QVS3
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS00930
gene id: 574087:acear_RS00930
uniprot id: D9QTD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

574087:acear RS10945
gene id: 574087:acear_RS10945
uniprot id: D9QTS0
names: Subcellular Location Annotation
messages: Membrane

574087:acear RS02995
gene id: 574087:acear_RS02995
uniprot id: D9QV38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

574087:acear RS00040
gene id: 574087:acear_RS00040
uniprot id: D9QSA4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

574087:acear RS10840
gene id: 574087:acear_RS10840
uniprot id: D9QTC3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

574087:acear RS03525
gene id: 574087:acear_RS03525
uniprot id: D9QVE3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

574087:acear RS05580
gene id: 574087:acear_RS05580
uniprot id: D9QPZ6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

574087:acear RS09510
gene id: 574087:acear_RS09510
uniprot id: D9QS67
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

574087:acear RS08420
gene id: 574087:acear_RS08420
uniprot id: D9QRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

574087:acear RS08800
gene id: 574087:acear_RS08800
uniprot id: D9QRS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

574087:acear RS11810
gene id: 574087:acear_RS11810
uniprot id: D9QUK5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

574087:acear RS03245
gene id: 574087:acear_RS03245
uniprot id: D9QV86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

574087:acear RS09495
gene id: 574087:acear_RS09495
uniprot id: D9QS64
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

574087:acear RS01575
gene id: 574087:acear_RS01575
uniprot id: D9QU43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

574087:acear RS10625
gene id: 574087:acear_RS10625
uniprot id: D9QT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

574087:acear RS01085
gene id: 574087:acear_RS01085
uniprot id: D9QTH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

574087:acear RS06840
gene id: 574087:acear_RS06840
uniprot id: D9QQP9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

574087:acear RS08635
gene id: 574087:acear_RS08635
uniprot id: D9QRP0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

574087:acear RS06290
gene id: 574087:acear_RS06290
uniprot id: D9QQD9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

574087:acear RS09415
gene id: 574087:acear_RS09415
uniprot id: D9QS48
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

574087:acear RS00625
gene id: 574087:acear_RS00625
uniprot id: D9QSX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

574087:acear RS08065
gene id: 574087:acear_RS08065
uniprot id: D9QRC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

574087:acear RS07365
gene id: 574087:acear_RS07365
uniprot id: D9QQZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

574087:acear RS08440
gene id: 574087:acear_RS08440
uniprot id: D9QRK1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

574087:acear RS08895
gene id: 574087:acear_RS08895
uniprot id: D9QRU3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

574087:acear RS09445
gene id: 574087:acear_RS09445
uniprot id: D9QS54
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

574087:acear RS03830
gene id: 574087:acear_RS03830
uniprot id: D9QVK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

574087:acear RS07985
gene id: 574087:acear_RS07985
uniprot id: D9QRB4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

574087:acear RS05700
gene id: 574087:acear_RS05700
uniprot id: D9QQ18
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

574087:acear RS04515
gene id: 574087:acear_RS04515
uniprot id: D9QVX3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

574087:acear RS01515
gene id: 574087:acear_RS01515
uniprot id: D9QU31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

574087:acear RS07535
gene id: 574087:acear_RS07535
uniprot id: D9QR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

574087:acear RS11920
gene id: 574087:acear_RS11920
uniprot id: D9QUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

574087:acear RS02630
gene id: 574087:acear_RS02630
uniprot id: D9QUX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

574087:acear RS10230
gene id: 574087:acear_RS10230
uniprot id: D9QSP1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

574087:acear RS08390
gene id: 574087:acear_RS08390
uniprot id: D9QRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

574087:acear RS06245
gene id: 574087:acear_RS06245
uniprot id: D9QQD0
names: Similarity
messages: Belongs to the EamA transporter family.

574087:acear RS07405
gene id: 574087:acear_RS07405
uniprot id: D9QR01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

574087:acear RS11340
gene id: 574087:acear_RS11340
uniprot id: D9QTZ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

574087:acear RS05110
gene id: 574087:acear_RS05110
uniprot id: D9QPQ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

574087:acear RS08145
gene id: 574087:acear_RS08145
uniprot id: D9QRE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

574087:acear RS01670
gene id: 574087:acear_RS01670
uniprot id: D9QU62
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

574087:acear RS01665
gene id: 574087:acear_RS01665
uniprot id: D9QU61
names: Similarity
messages: Belongs to the NadC/ModD family.

574087:acear RS08585
gene id: 574087:acear_RS08585
uniprot id: D9QRN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

574087:acear RS07940
gene id: 574087:acear_RS07940
uniprot id: D9QRA5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

574087:acear RS08160
gene id: 574087:acear_RS08160
uniprot id: D9QRE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

574087:acear RS06600
gene id: 574087:acear_RS06600
uniprot id: D9QQJ9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

574087:acear RS12880
gene id: 574087:acear_RS12880
uniprot id: D9QTT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

574087:acear RS07355
gene id: 574087:acear_RS07355
uniprot id: D9QQZ1
names: Similarity
messages: Belongs to the asp23 family.

574087:acear RS10485
gene id: 574087:acear_RS10485
uniprot id: D9QT53
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

574087:acear RS03610
gene id: 574087:acear_RS03610
uniprot id: D9QVG1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

574087:acear RS07285
gene id: 574087:acear_RS07285
uniprot id: D9QQX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

574087:acear RS01425
gene id: 574087:acear_RS01425
uniprot id: D9QTP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cytosol

574087:acear RS04855
gene id: 574087:acear_RS04855
uniprot id: D9QPK8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

574087:acear RS08315
gene id: 574087:acear_RS08315
uniprot id: D9QRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

574087:acear RS00495
gene id: 574087:acear_RS00495
uniprot id: D9QSV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

574087:acear RS01985
gene id: 574087:acear_RS01985
uniprot id: D9QUC0
names: Subcellular Location Annotation
messages: Membrane