573370:DMR RS20645
gene id: 573370:DMR_RS20645
uniprot id: C4XQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS11465
gene id: 573370:DMR_RS11465
uniprot id: C4XT94
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

573370:DMR RS22495
gene id: 573370:DMR_RS22495
uniprot id: C4XJG1
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS10795
gene id: 573370:DMR_RS10795
uniprot id: C4XSR5
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS15520
gene id: 573370:DMR_RS15520
uniprot id: C4XJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

573370:DMR RS15220
gene id: 573370:DMR_RS15220
uniprot id: C4XJB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

573370:DMR RS11340
gene id: 573370:DMR_RS11340
uniprot id: C4XT62
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

573370:DMR RS13755
gene id: 573370:DMR_RS13755
uniprot id: C4XHH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

573370:DMR RS21705
gene id: 573370:DMR_RS21705
uniprot id: C4XS18
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS10060
gene id: 573370:DMR_RS10060
uniprot id: C4XS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

573370:DMR RS12550
gene id: 573370:DMR_RS12550
uniprot id: C4XU93
names: Similarity
messages: Belongs to the UPF0047 family.

573370:DMR RS13680
gene id: 573370:DMR_RS13680
uniprot id: C4XH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS12080
gene id: 573370:DMR_RS12080
uniprot id: C4XTZ8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

573370:DMR RS05710
gene id: 573370:DMR_RS05710
uniprot id: C4XLK4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

573370:DMR RS10285
gene id: 573370:DMR_RS10285
uniprot id: C4XSD5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

573370:DMR RS16000
gene id: 573370:DMR_RS16000
uniprot id: C4XKE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

573370:DMR RS02915
gene id: 573370:DMR_RS02915
uniprot id: C4XIU6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

573370:DMR RS00905
gene id: 573370:DMR_RS00905
uniprot id: C4XGD1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

573370:DMR RS05805
gene id: 573370:DMR_RS05805
uniprot id: C4XMG6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

573370:DMR RS04920
gene id: 573370:DMR_RS04920
uniprot id: C4XLI4
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS00015
gene id: 573370:DMR_RS00015
uniprot id: C4XT12
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

573370:DMR RS13220
gene id: 573370:DMR_RS13220
uniprot id: C4XGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

573370:DMR RS02495
gene id: 573370:DMR_RS02495
uniprot id: C4XI63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573370:DMR RS00135
gene id: 573370:DMR_RS00135
uniprot id: C4XT36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS10115
gene id: 573370:DMR_RS10115
uniprot id: C4XSA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS05010
gene id: 573370:DMR_RS05010
uniprot id: C4XLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

573370:DMR RS00380
gene id: 573370:DMR_RS00380
uniprot id: C4XTQ2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

573370:DMR RS12100
gene id: 573370:DMR_RS12100
uniprot id: C4XU02
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS17770
gene id: 573370:DMR_RS17770
uniprot id: C4XMY2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

573370:DMR RS04875
gene id: 573370:DMR_RS04875
uniprot id: C4XL29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

573370:DMR RS08830
gene id: 573370:DMR_RS08830
uniprot id: C4XQK8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

573370:DMR RS10005
gene id: 573370:DMR_RS10005
uniprot id: C4XS79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

573370:DMR RS11325
gene id: 573370:DMR_RS11325
uniprot id: C4XT59
names: Similarity
messages: Belongs to the ClpA/ClpB family.

573370:DMR RS08610
gene id: 573370:DMR_RS08610
uniprot id: C4XQF4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

573370:DMR RS17995
gene id: 573370:DMR_RS17995
uniprot id: C4XN26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

573370:DMR RS01570
gene id: 573370:DMR_RS01570
uniprot id: C4XH73
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

573370:DMR RS10290
gene id: 573370:DMR_RS10290
uniprot id: C4XSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

573370:DMR RS01650
gene id: 573370:DMR_RS01650
uniprot id: C4XH89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

573370:DMR RS04485
gene id: 573370:DMR_RS04485
uniprot id: C4XK61
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10215
gene id: 573370:DMR_RS10215
uniprot id: C4XSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573370:DMR RS10815
gene id: 573370:DMR_RS10815
uniprot id: C4XSR9
names: Similarity
messages: Belongs to the AOR/FOR family.

573370:DMR RS02030
gene id: 573370:DMR_RS02030
uniprot id: C4XHG3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

573370:DMR RS20335
gene id: 573370:DMR_RS20335
uniprot id: C4XQS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

573370:DMR RS00090
gene id: 573370:DMR_RS00090
uniprot id: C4XT27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS09590
gene id: 573370:DMR_RS09590
uniprot id: C4XRH5
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS07800
gene id: 573370:DMR_RS07800
uniprot id: C4XPH9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

573370:DMR RS17480
gene id: 573370:DMR_RS17480
uniprot id: C4XMA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS13650
gene id: 573370:DMR_RS13650
uniprot id: C4XH29
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS17400
gene id: 573370:DMR_RS17400
uniprot id: C4XM83
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

573370:DMR RS14895
gene id: 573370:DMR_RS14895
uniprot id: C4XIP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

573370:DMR RS07935
gene id: 573370:DMR_RS07935
uniprot id: C4XPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

573370:DMR RS14585
gene id: 573370:DMR_RS14585
uniprot id: C4XIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

573370:DMR RS19365
gene id: 573370:DMR_RS19365
uniprot id: C4XPQ2
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS03055
gene id: 573370:DMR_RS03055
uniprot id: C4XIX3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573370:DMR RS07415
gene id: 573370:DMR_RS07415
uniprot id: C4XPA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

573370:DMR RS05960
gene id: 573370:DMR_RS05960
uniprot id: C4XMJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

573370:DMR RS22655
gene id: 573370:DMR_RS22655
uniprot id: C4XPU6
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS09975
gene id: 573370:DMR_RS09975
uniprot id: C4XS73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

573370:DMR RS06610
gene id: 573370:DMR_RS06610
uniprot id: C4XNE4
names: Similarity
names: Subunit
messages: Belongs to the organic radical-activating enzymes family.
messages: Monomer.

573370:DMR RS11120
gene id: 573370:DMR_RS11120
uniprot id: C4XSX8
names: Similarity
messages: Belongs to the fabD family.

573370:DMR RS21800
gene id: 573370:DMR_RS21800
uniprot id: C4XSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

573370:DMR RS04995
gene id: 573370:DMR_RS04995
uniprot id: C4XLJ8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

573370:DMR RS15045
gene id: 573370:DMR_RS15045
uniprot id: C4XIR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS07540
gene id: 573370:DMR_RS07540
uniprot id: C4XPD2
names: Similarity
messages: Belongs to the MotB family.

573370:DMR RS13575
gene id: 573370:DMR_RS13575
uniprot id: C4XH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

573370:DMR RS21820
gene id: 573370:DMR_RS21820
uniprot id: C4XSH8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

573370:DMR RS16065
gene id: 573370:DMR_RS16065
uniprot id: C4XKF8
names: Similarity
messages: Belongs to the DprA/Smf family.

573370:DMR RS14985
gene id: 573370:DMR_RS14985
uniprot id: C4XIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

573370:DMR RS06380
gene id: 573370:DMR_RS06380
uniprot id: C4XMT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573370:DMR RS11275
gene id: 573370:DMR_RS11275
uniprot id: C4XSN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Belongs to the pseudouridine synthase RluA family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

573370:DMR RS15125
gene id: 573370:DMR_RS15125
uniprot id: C4XIM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

573370:DMR RS12145
gene id: 573370:DMR_RS12145
uniprot id: C4XU11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

573370:DMR RS01770
gene id: 573370:DMR_RS01770
uniprot id: C4XHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

573370:DMR RS11320
gene id: 573370:DMR_RS11320
uniprot id: C4XT58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

573370:DMR RS12610
gene id: 573370:DMR_RS12610
uniprot id: C4XUA5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

573370:DMR RS14455
gene id: 573370:DMR_RS14455
uniprot id: C4XIE3
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS13150
gene id: 573370:DMR_RS13150
uniprot id: C4XGS4
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS20845
gene id: 573370:DMR_RS20845
uniprot id: C4XR31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS03065
gene id: 573370:DMR_RS03065
uniprot id: C4XIX5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS12980
gene id: 573370:DMR_RS12980
uniprot id: C4XGP3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573370:DMR RS18545
gene id: 573370:DMR_RS18545
uniprot id: C4XND4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

573370:DMR RS05205
gene id: 573370:DMR_RS05205
uniprot id: C4XLP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

573370:DMR RS02125
gene id: 573370:DMR_RS02125
uniprot id: C4XHY8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

573370:DMR RS09640
gene id: 573370:DMR_RS09640
uniprot id: C4XRI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

573370:DMR RS13655
gene id: 573370:DMR_RS13655
uniprot id: C4XH30
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573370:DMR RS12365
gene id: 573370:DMR_RS12365
uniprot id: C4XU55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

573370:DMR RS14095
gene id: 573370:DMR_RS14095
uniprot id: C4XHQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

573370:DMR RS04235
gene id: 573370:DMR_RS04235
uniprot id: C4XK08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

573370:DMR RS11515
gene id: 573370:DMR_RS11515
uniprot id: C4XTA5
names: Similarity
messages: Belongs to the YciI family.

573370:DMR RS21560
gene id: 573370:DMR_RS21560
uniprot id: C4XRY8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

573370:DMR RS10480
gene id: 573370:DMR_RS10480
uniprot id: C4XSJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS01680
gene id: 573370:DMR_RS01680
uniprot id: C4XH95
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08880
gene id: 573370:DMR_RS08880
uniprot id: C4XQL8
names: Similarity
messages: Belongs to the CutA family.

573370:DMR RS20830
gene id: 573370:DMR_RS20830
uniprot id: C4XR28
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS01755
gene id: 573370:DMR_RS01755
uniprot id: C4XHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

573370:DMR RS13700
gene id: 573370:DMR_RS13700
uniprot id: C4XH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS02385
gene id: 573370:DMR_RS02385
uniprot id: C4XI41
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

573370:DMR RS09000
gene id: 573370:DMR_RS09000
uniprot id: C4XR60
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573370:DMR RS03155
gene id: 573370:DMR_RS03155
uniprot id: C4XIZ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS14650
gene id: 573370:DMR_RS14650
uniprot id: C4XII8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

573370:DMR RS21275
gene id: 573370:DMR_RS21275
uniprot id: C4XRT1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

573370:DMR RS01825
gene id: 573370:DMR_RS01825
uniprot id: C4XHC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

573370:DMR RS02015
gene id: 573370:DMR_RS02015
uniprot id: C4XHG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS13415
gene id: 573370:DMR_RS13415
uniprot id: C4XGY0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS11270
gene id: 573370:DMR_RS11270
uniprot id: C4XSM9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS04810
gene id: 573370:DMR_RS04810
uniprot id: C4XL16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573370:DMR RS19410
gene id: 573370:DMR_RS19410
uniprot id: C4XPR0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS05190
gene id: 573370:DMR_RS05190
uniprot id: C4XLP3
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS17945
gene id: 573370:DMR_RS17945
uniprot id: C4XN17
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08015
gene id: 573370:DMR_RS08015
uniprot id: C4XPM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

573370:DMR RS13525
gene id: 573370:DMR_RS13525
uniprot id: C4XH02
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

573370:DMR RS02290
gene id: 573370:DMR_RS02290
uniprot id: C4XI21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS21575
gene id: 573370:DMR_RS21575
uniprot id: C4XRZ1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

573370:DMR RS18770
gene id: 573370:DMR_RS18770
uniprot id: C4XNY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

573370:DMR RS03535
gene id: 573370:DMR_RS03535
uniprot id: C4XJ62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS16070
gene id: 573370:DMR_RS16070
uniprot id: C4XKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

573370:DMR RS21565
gene id: 573370:DMR_RS21565
uniprot id: C4XRY9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

573370:DMR RS09940
gene id: 573370:DMR_RS09940
uniprot id: C4XS67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

573370:DMR RS07430
gene id: 573370:DMR_RS07430
uniprot id: C4XPB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS13950
gene id: 573370:DMR_RS13950
uniprot id: C4XHL7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS19905
gene id: 573370:DMR_RS19905
uniprot id: C4XQ23
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

573370:DMR RS09825
gene id: 573370:DMR_RS09825
uniprot id: C4XS44
names: Similarity
messages: Belongs to the peptidase M29 family.

573370:DMR RS10300
gene id: 573370:DMR_RS10300
uniprot id: C4XSD8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

573370:DMR RS09780
gene id: 573370:DMR_RS09780
uniprot id: C4XS35
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

573370:DMR RS06415
gene id: 573370:DMR_RS06415
uniprot id: C4XMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

573370:DMR RS05645
gene id: 573370:DMR_RS05645
uniprot id: C4XLY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

573370:DMR RS21755
gene id: 573370:DMR_RS21755
uniprot id: C4XSG2
names: Similarity
messages: Belongs to the glutamate synthase family.

573370:DMR RS14330
gene id: 573370:DMR_RS14330
uniprot id: C4XHW0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS14690
gene id: 573370:DMR_RS14690
uniprot id: C4XIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

573370:DMR RS07070
gene id: 573370:DMR_RS07070
uniprot id: C4XNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

573370:DMR RS02695
gene id: 573370:DMR_RS02695
uniprot id: C4XIA3
names: Similarity
messages: Belongs to the class-I fumarase family.

573370:DMR RS18000
gene id: 573370:DMR_RS18000
uniprot id: C4XN27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

573370:DMR RS08090
gene id: 573370:DMR_RS08090
uniprot id: C4XPJ8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

573370:DMR RS02760
gene id: 573370:DMR_RS02760
uniprot id: C4XIB6
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS00940
gene id: 573370:DMR_RS00940
uniprot id: C4XGD8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

573370:DMR RS09435
gene id: 573370:DMR_RS09435
uniprot id: C4XRE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

573370:DMR RS18160
gene id: 573370:DMR_RS18160
uniprot id: C4XN58
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS17980
gene id: 573370:DMR_RS17980
uniprot id: C4XN23
names: Similarity
messages: Belongs to the peptidase M16 family.

573370:DMR RS12830
gene id: 573370:DMR_RS12830
uniprot id: C4XUF4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS21740
gene id: 573370:DMR_RS21740
uniprot id: C4XSF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573370:DMR RS10360
gene id: 573370:DMR_RS10360
uniprot id: C4XSF0
names: Similarity
messages: Belongs to the UPF0235 family.

573370:DMR RS01425
gene id: 573370:DMR_RS01425
uniprot id: C4XH48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

573370:DMR RS08345
gene id: 573370:DMR_RS08345
uniprot id: C4XQA3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS20345
gene id: 573370:DMR_RS20345
uniprot id: C4XQS8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

573370:DMR RS03780
gene id: 573370:DMR_RS03780
uniprot id: C4XJS0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

573370:DMR RS14200
gene id: 573370:DMR_RS14200
uniprot id: C4XHS5
names: Similarity
messages: Belongs to the peptidase C59 family.

573370:DMR RS19825
gene id: 573370:DMR_RS19825
uniprot id: C4XQ06
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS05405
gene id: 573370:DMR_RS05405
uniprot id: C4XLT7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

573370:DMR RS02635
gene id: 573370:DMR_RS02635
uniprot id: C4XI91
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

573370:DMR RS00345
gene id: 573370:DMR_RS00345
uniprot id: C4XHQ4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS11720
gene id: 573370:DMR_RS11720
uniprot id: C4XTE6
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

573370:DMR RS02225
gene id: 573370:DMR_RS02225
uniprot id: C4XI08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

573370:DMR RS02685
gene id: 573370:DMR_RS02685
uniprot id: C4XIA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

573370:DMR RS09985
gene id: 573370:DMR_RS09985
uniprot id: C4XS75
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

573370:DMR RS06680
gene id: 573370:DMR_RS06680
uniprot id: C4XNF8
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS23185
gene id: 573370:DMR_RS23185
uniprot id: C4XLZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

573370:DMR RS14265
gene id: 573370:DMR_RS14265
uniprot id: C4XHU4
names: Similarity
messages: Belongs to the AOR/FOR family.

573370:DMR RS00035
gene id: 573370:DMR_RS00035
uniprot id: C4XT16
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS08240
gene id: 573370:DMR_RS08240
uniprot id: C4XQ83
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

573370:DMR RS03920
gene id: 573370:DMR_RS03920
uniprot id: C4XJU6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

573370:DMR RS20120
gene id: 573370:DMR_RS20120
uniprot id: C4XQN3
names: Similarity
messages: Belongs to the asparagine synthetase family.

573370:DMR RS17900
gene id: 573370:DMR_RS17900
uniprot id: C4XN08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

573370:DMR RS09725
gene id: 573370:DMR_RS09725
uniprot id: C4XRK2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

573370:DMR RS06350
gene id: 573370:DMR_RS06350
uniprot id: C4XMS5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

573370:DMR RS10680
gene id: 573370:DMR_RS10680
uniprot id: C4XSP2
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS11170
gene id: 573370:DMR_RS11170
uniprot id: C4XSY8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

573370:DMR RS12945
gene id: 573370:DMR_RS12945
uniprot id: C4XGN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

573370:DMR RS21665
gene id: 573370:DMR_RS21665
uniprot id: C4XS09
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS05460
gene id: 573370:DMR_RS05460
uniprot id: C4XLU8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

573370:DMR RS05560
gene id: 573370:DMR_RS05560
uniprot id: C4XLW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

573370:DMR RS12690
gene id: 573370:DMR_RS12690
uniprot id: C4XUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

573370:DMR RS01145
gene id: 573370:DMR_RS01145
uniprot id: C4XGH9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

573370:DMR RS21145
gene id: 573370:DMR_RS21145
uniprot id: C4XRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

573370:DMR RS05350
gene id: 573370:DMR_RS05350
uniprot id: C4XLS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

573370:DMR RS04190
gene id: 573370:DMR_RS04190
uniprot id: C4XK00
names: Similarity
messages: Belongs to the UPF0111 family.

573370:DMR RS14240
gene id: 573370:DMR_RS14240
uniprot id: C4XHT9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS03925
gene id: 573370:DMR_RS03925
uniprot id: C4XJU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573370:DMR RS07145
gene id: 573370:DMR_RS07145
uniprot id: C4XNS0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

573370:DMR RS07585
gene id: 573370:DMR_RS07585
uniprot id: C4XPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

573370:DMR RS15650
gene id: 573370:DMR_RS15650
uniprot id: C4XK67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

573370:DMR RS16095
gene id: 573370:DMR_RS16095
uniprot id: C4XKG4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS05845
gene id: 573370:DMR_RS05845
uniprot id: C4XMH4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS15105
gene id: 573370:DMR_RS15105
uniprot id: C4XIM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

573370:DMR RS09995
gene id: 573370:DMR_RS09995
uniprot id: C4XS77
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

573370:DMR RS09345
gene id: 573370:DMR_RS09345
uniprot id: C4XRC7
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

573370:DMR RS16730
gene id: 573370:DMR_RS16730
uniprot id: C4XL85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

573370:DMR RS10320
gene id: 573370:DMR_RS10320
uniprot id: C4XSE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573370:DMR RS18795
gene id: 573370:DMR_RS18795
uniprot id: C4XNY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

573370:DMR RS00990
gene id: 573370:DMR_RS00990
uniprot id: C4XGE8
names: Similarity
messages: Belongs to the AOR/FOR family.

573370:DMR RS10850
gene id: 573370:DMR_RS10850
uniprot id: C4XSS6
names: Similarity
messages: Belongs to the universal stress protein A family.

573370:DMR RS08580
gene id: 573370:DMR_RS08580
uniprot id: C4XQE8
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

573370:DMR RS00580
gene id: 573370:DMR_RS00580
uniprot id: C4XRR2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS09450
gene id: 573370:DMR_RS09450
uniprot id: C4XRE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

573370:DMR RS09655
gene id: 573370:DMR_RS09655
uniprot id: C4XRI8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

573370:DMR RS15150
gene id: 573370:DMR_RS15150
uniprot id: C4XJA4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

573370:DMR RS14085
gene id: 573370:DMR_RS14085
uniprot id: C4XHQ7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

573370:DMR RS06310
gene id: 573370:DMR_RS06310
uniprot id: C4XMR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS09805
gene id: 573370:DMR_RS09805
uniprot id: C4XS40
names: Similarity
messages: Belongs to the UPF0178 family.

573370:DMR RS17850
gene id: 573370:DMR_RS17850
uniprot id: C4XMZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS13845
gene id: 573370:DMR_RS13845
uniprot id: C4XHJ6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

573370:DMR RS12700
gene id: 573370:DMR_RS12700
uniprot id: C4XUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

573370:DMR RS19780
gene id: 573370:DMR_RS19780
uniprot id: C4XPZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

573370:DMR RS03705
gene id: 573370:DMR_RS03705
uniprot id: C4XJ96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573370:DMR RS15185
gene id: 573370:DMR_RS15185
uniprot id: C4XJB1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

573370:DMR RS13685
gene id: 573370:DMR_RS13685
uniprot id: C4XH36
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573370:DMR RS12905
gene id: 573370:DMR_RS12905
uniprot id: C4XUF0
names: Similarity
messages: Belongs to the TlyA family.

573370:DMR RS00330
gene id: 573370:DMR_RS00330
uniprot id: C4XTP2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

573370:DMR RS15450
gene id: 573370:DMR_RS15450
uniprot id: C4XJM9
names: Similarity
messages: Belongs to the RemA family.

573370:DMR RS02345
gene id: 573370:DMR_RS02345
uniprot id: C4XI32
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

573370:DMR RS05610
gene id: 573370:DMR_RS05610
uniprot id: C4XLX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

573370:DMR RS15755
gene id: 573370:DMR_RS15755
uniprot id: C4XK97
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

573370:DMR RS11155
gene id: 573370:DMR_RS11155
uniprot id: C4XSY4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS08575
gene id: 573370:DMR_RS08575
uniprot id: C4XQE7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

573370:DMR RS11455
gene id: 573370:DMR_RS11455
uniprot id: C4XT92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

573370:DMR RS05315
gene id: 573370:DMR_RS05315
uniprot id: C4XLR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

573370:DMR RS19105
gene id: 573370:DMR_RS19105
uniprot id: C4XP51
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS02690
gene id: 573370:DMR_RS02690
uniprot id: C4XIA2
names: Similarity
messages: Belongs to the class-I fumarase family.

573370:DMR RS09795
gene id: 573370:DMR_RS09795
uniprot id: C4XS38
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

573370:DMR RS07315
gene id: 573370:DMR_RS07315
uniprot id: C4XP90
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS17970
gene id: 573370:DMR_RS17970
uniprot id: C4XN21
names: Similarity
messages: Belongs to the PspA/IM30 family.

573370:DMR RS09080
gene id: 573370:DMR_RS09080
uniprot id: C4XHQ4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS04495
gene id: 573370:DMR_RS04495
uniprot id: C4XK63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

573370:DMR RS14395
gene id: 573370:DMR_RS14395
uniprot id: C4XGR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS06160
gene id: 573370:DMR_RS06160
uniprot id: C4XMN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

573370:DMR RS08355
gene id: 573370:DMR_RS08355
uniprot id: C4XQA5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

573370:DMR RS13310
gene id: 573370:DMR_RS13310
uniprot id: C4XGV9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

573370:DMR RS04130
gene id: 573370:DMR_RS04130
uniprot id: C4XJY8
names: Similarity
messages: Belongs to the alkaline phosphatase family.

573370:DMR RS15545
gene id: 573370:DMR_RS15545
uniprot id: C4XJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

573370:DMR RS02330
gene id: 573370:DMR_RS02330
uniprot id: C4XI29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

573370:DMR RS08445
gene id: 573370:DMR_RS08445
uniprot id: C4XQC2
names: Similarity
messages: Belongs to the peptidase C40 family.

573370:DMR RS16175
gene id: 573370:DMR_RS16175
uniprot id: C4XKI0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

573370:DMR RS10590
gene id: 573370:DMR_RS10590
uniprot id: C4XSL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

573370:DMR RS10420
gene id: 573370:DMR_RS10420
uniprot id: C4XS28
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

573370:DMR RS14100
gene id: 573370:DMR_RS14100
uniprot id: C4XHQ9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

573370:DMR RS21255
gene id: 573370:DMR_RS21255
uniprot id: C4XRS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

573370:DMR RS18785
gene id: 573370:DMR_RS18785
uniprot id: C4XNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

573370:DMR RS09630
gene id: 573370:DMR_RS09630
uniprot id: C4XRI3
names: Similarity
messages: Belongs to the HypD family.

573370:DMR RS05900
gene id: 573370:DMR_RS05900
uniprot id: C4XMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

573370:DMR RS15425
gene id: 573370:DMR_RS15425
uniprot id: C4XJM4
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS10725
gene id: 573370:DMR_RS10725
uniprot id: C4XSQ1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS15035
gene id: 573370:DMR_RS15035
uniprot id: C4XIR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.

573370:DMR RS16925
gene id: 573370:DMR_RS16925
uniprot id: C4XLC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

573370:DMR RS05685
gene id: 573370:DMR_RS05685
uniprot id: C4XLZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

573370:DMR RS06755
gene id: 573370:DMR_RS06755
uniprot id: C4XNH4
names: Similarity
messages: Belongs to the MobA/MobL family.

573370:DMR RS06830
gene id: 573370:DMR_RS06830
uniprot id: C4XNJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

573370:DMR RS18245
gene id: 573370:DMR_RS18245
uniprot id: C4XN75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

573370:DMR RS21660
gene id: 573370:DMR_RS21660
uniprot id: C4XS08
names: Similarity
messages: Belongs to the peptidase S16 family.

573370:DMR RS13880
gene id: 573370:DMR_RS13880
uniprot id: C4XHK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

573370:DMR RS10885
gene id: 573370:DMR_RS10885
uniprot id: C4XST2
names: Similarity
messages: Belongs to the AOR/FOR family.

573370:DMR RS07450
gene id: 573370:DMR_RS07450
uniprot id: C4XPB5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS00340
gene id: 573370:DMR_RS00340
uniprot id: C4XTP4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

573370:DMR RS21610
gene id: 573370:DMR_RS21610
uniprot id: C4XRZ8
names: Similarity
messages: Belongs to the histone deacetylase family.

573370:DMR RS00860
gene id: 573370:DMR_RS00860
uniprot id: C4XGC2
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

573370:DMR RS02060
gene id: 573370:DMR_RS02060
uniprot id: C4XHG9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

573370:DMR RS07895
gene id: 573370:DMR_RS07895
uniprot id: C4XPJ7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08380
gene id: 573370:DMR_RS08380
uniprot id: C4XQA9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

573370:DMR RS18995
gene id: 573370:DMR_RS18995
uniprot id: C4XP26
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573370:DMR RS03830
gene id: 573370:DMR_RS03830
uniprot id: C4XJT0
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS20775
gene id: 573370:DMR_RS20775
uniprot id: C4XR17
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

573370:DMR RS00045
gene id: 573370:DMR_RS00045
uniprot id: C4XT18
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10270
gene id: 573370:DMR_RS10270
uniprot id: C4XSD2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS14560
gene id: 573370:DMR_RS14560
uniprot id: C4XIH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

573370:DMR RS15155
gene id: 573370:DMR_RS15155
uniprot id: C4XJA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

573370:DMR RS16405
gene id: 573370:DMR_RS16405
uniprot id: C4XKM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

573370:DMR RS03370
gene id: 573370:DMR_RS03370
uniprot id: C4XJ33
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS07560
gene id: 573370:DMR_RS07560
uniprot id: C4XPD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

573370:DMR RS07625
gene id: 573370:DMR_RS07625
uniprot id: C4XPE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

573370:DMR RS08370
gene id: 573370:DMR_RS08370
uniprot id: C4XQA7
names: Subcellular Location Annotation
messages: Cell inner membrane

573370:DMR RS09710
gene id: 573370:DMR_RS09710
uniprot id: C4XRJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

573370:DMR RS11050
gene id: 573370:DMR_RS11050
uniprot id: C4XSW4
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

573370:DMR RS07940
gene id: 573370:DMR_RS07940
uniprot id: C4XPK8
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

573370:DMR RS20320
gene id: 573370:DMR_RS20320
uniprot id: C4XQS3
names: Similarity
messages: Belongs to the peptidase S33 family.

573370:DMR RS05585
gene id: 573370:DMR_RS05585
uniprot id: C4XLX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

573370:DMR RS05830
gene id: 573370:DMR_RS05830
uniprot id: C4XMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

573370:DMR RS06130
gene id: 573370:DMR_RS06130
uniprot id: C4XMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS05670
gene id: 573370:DMR_RS05670
uniprot id: C4XLZ1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

573370:DMR RS14065
gene id: 573370:DMR_RS14065
uniprot id: C4XHQ4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS03820
gene id: 573370:DMR_RS03820
uniprot id: C4XJS8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS11630
gene id: 573370:DMR_RS11630
uniprot id: C4XTC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

573370:DMR RS16970
gene id: 573370:DMR_RS16970
uniprot id: C4XLD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

573370:DMR RS03805
gene id: 573370:DMR_RS03805
uniprot id: C4XJS5
names: Similarity
messages: Belongs to the FrhG family.

573370:DMR RS12270
gene id: 573370:DMR_RS12270
uniprot id: C4XU37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

573370:DMR RS21285
gene id: 573370:DMR_RS21285
uniprot id: C4XRT3
names: Subcellular Location Annotation
messages: Cytoplasm

573370:DMR RS19890
gene id: 573370:DMR_RS19890
uniprot id: C4XQ20
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

573370:DMR RS20855
gene id: 573370:DMR_RS20855
uniprot id: C4XR33
names: Similarity
messages: Belongs to the ComB family.

573370:DMR RS04390
gene id: 573370:DMR_RS04390
uniprot id: C4XK41
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS11615
gene id: 573370:DMR_RS11615
uniprot id: C4XTC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

573370:DMR RS01820
gene id: 573370:DMR_RS01820
uniprot id: C4XHC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

573370:DMR RS05810
gene id: 573370:DMR_RS05810
uniprot id: C4XMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

573370:DMR RS07580
gene id: 573370:DMR_RS07580
uniprot id: C4XPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

573370:DMR RS06155
gene id: 573370:DMR_RS06155
uniprot id: C4XMN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS17455
gene id: 573370:DMR_RS17455
uniprot id: C4XM96
names: Similarity
messages: Belongs to the universal stress protein A family.

573370:DMR RS18745
gene id: 573370:DMR_RS18745
uniprot id: C4XNX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

573370:DMR RS05400
gene id: 573370:DMR_RS05400
uniprot id: C4XLT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

573370:DMR RS08040
gene id: 573370:DMR_RS08040
uniprot id: C4XPM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

573370:DMR RS19970
gene id: 573370:DMR_RS19970
uniprot id: C4XQ36
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

573370:DMR RS02705
gene id: 573370:DMR_RS02705
uniprot id: C4XIA5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

573370:DMR RS10965
gene id: 573370:DMR_RS10965
uniprot id: C4XSU8
names: Similarity
messages: Belongs to the MlaA family.

573370:DMR RS06890
gene id: 573370:DMR_RS06890
uniprot id: C4XNK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

573370:DMR RS14180
gene id: 573370:DMR_RS14180
uniprot id: C4XHS1
names: Similarity
messages: Belongs to the SUI1 family.

573370:DMR RS02795
gene id: 573370:DMR_RS02795
uniprot id: C4XIC3
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

573370:DMR RS03785
gene id: 573370:DMR_RS03785
uniprot id: C4XJS1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

573370:DMR RS09205
gene id: 573370:DMR_RS09205
uniprot id: C4XR99
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

573370:DMR RS17210
gene id: 573370:DMR_RS17210
uniprot id: C4XM14
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS07255
gene id: 573370:DMR_RS07255
uniprot id: C4XNQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

573370:DMR RS07990
gene id: 573370:DMR_RS07990
uniprot id: C4XPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

573370:DMR RS12740
gene id: 573370:DMR_RS12740
uniprot id: C4XUD1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

573370:DMR RS18805
gene id: 573370:DMR_RS18805
uniprot id: C4XNY8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

573370:DMR RS08285
gene id: 573370:DMR_RS08285
uniprot id: C4XQ91
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

573370:DMR RS12895
gene id: 573370:DMR_RS12895
uniprot id: C4XUE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573370:DMR RS17030
gene id: 573370:DMR_RS17030
uniprot id: C4XLE7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

573370:DMR RS01055
gene id: 573370:DMR_RS01055
uniprot id: C4XGG1
names: Similarity
messages: Belongs to the peptidase S11 family.

573370:DMR RS08235
gene id: 573370:DMR_RS08235
uniprot id: C4XQ82
names: Similarity
messages: Belongs to the UPF0045 family.

573370:DMR RS09365
gene id: 573370:DMR_RS09365
uniprot id: C4XRD1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS06870
gene id: 573370:DMR_RS06870
uniprot id: C4XNK1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

573370:DMR RS08080
gene id: 573370:DMR_RS08080
uniprot id: C4XPN5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

573370:DMR RS05580
gene id: 573370:DMR_RS05580
uniprot id: C4XLX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

573370:DMR RS10435
gene id: 573370:DMR_RS10435
uniprot id: C4XSI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

573370:DMR RS07200
gene id: 573370:DMR_RS07200
uniprot id: C4XNT1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS09165
gene id: 573370:DMR_RS09165
uniprot id: C4XR90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

573370:DMR RS10785
gene id: 573370:DMR_RS10785
uniprot id: C4XSR3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS20995
gene id: 573370:DMR_RS20995
uniprot id: C4XRM6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573370:DMR RS13695
gene id: 573370:DMR_RS13695
uniprot id: C4XH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS00300
gene id: 573370:DMR_RS00300
uniprot id: C4XTN6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

573370:DMR RS14715
gene id: 573370:DMR_RS14715
uniprot id: C4XIK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

573370:DMR RS16470
gene id: 573370:DMR_RS16470
uniprot id: C4XK81
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

573370:DMR RS16815
gene id: 573370:DMR_RS16815
uniprot id: C4XLA4
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18085
gene id: 573370:DMR_RS18085
uniprot id: C4XN43
names: Similarity
messages: Belongs to the Skp family.

573370:DMR RS05990
gene id: 573370:DMR_RS05990
uniprot id: C4XMK4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

573370:DMR RS09790
gene id: 573370:DMR_RS09790
uniprot id: C4XS37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

573370:DMR RS15580
gene id: 573370:DMR_RS15580
uniprot id: C4XJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

573370:DMR RS03890
gene id: 573370:DMR_RS03890
uniprot id: C4XJU0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS02610
gene id: 573370:DMR_RS02610
uniprot id: C4XI86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573370:DMR RS15575
gene id: 573370:DMR_RS15575
uniprot id: C4XJQ3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

573370:DMR RS05850
gene id: 573370:DMR_RS05850
uniprot id: C4XMH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

573370:DMR RS17920
gene id: 573370:DMR_RS17920
uniprot id: C4XN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

573370:DMR RS02870
gene id: 573370:DMR_RS02870
uniprot id: C4XIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

573370:DMR RS07835
gene id: 573370:DMR_RS07835
uniprot id: C4XPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS20425
gene id: 573370:DMR_RS20425
uniprot id: C4XQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

573370:DMR RS15635
gene id: 573370:DMR_RS15635
uniprot id: C4XK64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

573370:DMR RS08815
gene id: 573370:DMR_RS08815
uniprot id: C4XQK6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

573370:DMR RS06650
gene id: 573370:DMR_RS06650
uniprot id: C4XNF2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

573370:DMR RS14770
gene id: 573370:DMR_RS14770
uniprot id: C4XIL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

573370:DMR RS20670
gene id: 573370:DMR_RS20670
uniprot id: C4XQZ6
names: Subcellular Location Annotation
messages: Cell inner membrane

573370:DMR RS11375
gene id: 573370:DMR_RS11375
uniprot id: C4XT76
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

573370:DMR RS09980
gene id: 573370:DMR_RS09980
uniprot id: C4XS74
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

573370:DMR RS01160
gene id: 573370:DMR_RS01160
uniprot id: C4XGI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

573370:DMR RS11095
gene id: 573370:DMR_RS11095
uniprot id: C4XSX3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

573370:DMR RS12930
gene id: 573370:DMR_RS12930
uniprot id: C4XGN3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

573370:DMR RS05860
gene id: 573370:DMR_RS05860
uniprot id: C4XMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS11430
gene id: 573370:DMR_RS11430
uniprot id: C4XT87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

573370:DMR RS15935
gene id: 573370:DMR_RS15935
uniprot id: C4XKD2
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS06895
gene id: 573370:DMR_RS06895
uniprot id: C4XNK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

573370:DMR RS16690
gene id: 573370:DMR_RS16690
uniprot id: C4XL77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

573370:DMR RS17465
gene id: 573370:DMR_RS17465
uniprot id: C4XM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

573370:DMR RS15705
gene id: 573370:DMR_RS15705
uniprot id: C4XK87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

573370:DMR RS08335
gene id: 573370:DMR_RS08335
uniprot id: C4XQA1
names: Similarity
messages: Belongs to the glutamate synthase family.

573370:DMR RS01600
gene id: 573370:DMR_RS01600
uniprot id: C4XH79
names: Similarity
messages: Belongs to the UPF0751 family.

573370:DMR RS12085
gene id: 573370:DMR_RS12085
uniprot id: C4XTZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

573370:DMR RS12175
gene id: 573370:DMR_RS12175
uniprot id: C4XU17
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS06305
gene id: 573370:DMR_RS06305
uniprot id: C4XMR6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

573370:DMR RS00765
gene id: 573370:DMR_RS00765
uniprot id: C4XGA3
names: Similarity
messages: Belongs to the HdrA family.

573370:DMR RS08415
gene id: 573370:DMR_RS08415
uniprot id: C4XQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

573370:DMR RS02040
gene id: 573370:DMR_RS02040
uniprot id: C4XHG5
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS00200
gene id: 573370:DMR_RS00200
uniprot id: C4XT49
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

573370:DMR RS10890
gene id: 573370:DMR_RS10890
uniprot id: C4XST3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

573370:DMR RS12675
gene id: 573370:DMR_RS12675
uniprot id: C4XUB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

573370:DMR RS05180
gene id: 573370:DMR_RS05180
uniprot id: C4XLP1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18435
gene id: 573370:DMR_RS18435
uniprot id: C4XNB2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

573370:DMR RS05415
gene id: 573370:DMR_RS05415
uniprot id: C4XLT9
names: Similarity
messages: Belongs to the UPF0047 family.

573370:DMR RS10665
gene id: 573370:DMR_RS10665
uniprot id: C4XSN9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

573370:DMR RS06675
gene id: 573370:DMR_RS06675
uniprot id: C4XNF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

573370:DMR RS17370
gene id: 573370:DMR_RS17370
uniprot id: C4XM77
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

573370:DMR RS18285
gene id: 573370:DMR_RS18285
uniprot id: C4XN83
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS00890
gene id: 573370:DMR_RS00890
uniprot id: C4XGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

573370:DMR RS08060
gene id: 573370:DMR_RS08060
uniprot id: C4XPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

573370:DMR RS04065
gene id: 573370:DMR_RS04065
uniprot id: C4XJX5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

573370:DMR RS10275
gene id: 573370:DMR_RS10275
uniprot id: C4XSD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

573370:DMR RS07640
gene id: 573370:DMR_RS07640
uniprot id: C4XPF2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

573370:DMR RS05625
gene id: 573370:DMR_RS05625
uniprot id: C4XLY1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

573370:DMR RS07405
gene id: 573370:DMR_RS07405
uniprot id: C4XPA6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

573370:DMR RS02130
gene id: 573370:DMR_RS02130
uniprot id: C4XHY9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

573370:DMR RS16180
gene id: 573370:DMR_RS16180
uniprot id: C4XKI1
names: Similarity
messages: Belongs to the class-I fumarase family.

573370:DMR RS07130
gene id: 573370:DMR_RS07130
uniprot id: C4XNR7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

573370:DMR RS12695
gene id: 573370:DMR_RS12695
uniprot id: C4XUC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS07425
gene id: 573370:DMR_RS07425
uniprot id: C4XPB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

573370:DMR RS16410
gene id: 573370:DMR_RS16410
uniprot id: C4XKM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

573370:DMR RS07175
gene id: 573370:DMR_RS07175
uniprot id: C4XNS6
names: Function
names: Similarity
messages: Belongs to the CbiK family.
messages: Catalyzes the insertion of Co(2+) into sirohydrochlorin.

573370:DMR RS06455
gene id: 573370:DMR_RS06455
uniprot id: C4XMU7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

573370:DMR RS12090
gene id: 573370:DMR_RS12090
uniprot id: C4XU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

573370:DMR RS20725
gene id: 573370:DMR_RS20725
uniprot id: C4XR07
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10730
gene id: 573370:DMR_RS10730
uniprot id: C4XSQ2
names: Subcellular Location Annotation
messages: Periplasm

573370:DMR RS15700
gene id: 573370:DMR_RS15700
uniprot id: C4XK86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

573370:DMR RS20710
gene id: 573370:DMR_RS20710
uniprot id: C4XR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS08410
gene id: 573370:DMR_RS08410
uniprot id: C4XQB5
names: Similarity
messages: Belongs to the aspartokinase family.

573370:DMR RS05230
gene id: 573370:DMR_RS05230
uniprot id: C4XLQ1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

573370:DMR RS10240
gene id: 573370:DMR_RS10240
uniprot id: C4XSC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

573370:DMR RS21265
gene id: 573370:DMR_RS21265
uniprot id: C4XRS9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

573370:DMR RS08265
gene id: 573370:DMR_RS08265
uniprot id: C4XQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

573370:DMR RS05510
gene id: 573370:DMR_RS05510
uniprot id: C4XLV8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

573370:DMR RS02880
gene id: 573370:DMR_RS02880
uniprot id: C4XIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

573370:DMR RS12280
gene id: 573370:DMR_RS12280
uniprot id: C4XU39
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

573370:DMR RS13350
gene id: 573370:DMR_RS13350
uniprot id: C4XGW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

573370:DMR RS21805
gene id: 573370:DMR_RS21805
uniprot id: C4XSH5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

573370:DMR RS13595
gene id: 573370:DMR_RS13595
uniprot id: C4XH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS15955
gene id: 573370:DMR_RS15955
uniprot id: C4XKD6
names: Similarity
messages: Belongs to the bacterial secretin family.

573370:DMR RS09765
gene id: 573370:DMR_RS09765
uniprot id: C4XS32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

573370:DMR RS09215
gene id: 573370:DMR_RS09215
uniprot id: C4XRA1
names: Similarity
messages: Belongs to the FeoA family.

573370:DMR RS14675
gene id: 573370:DMR_RS14675
uniprot id: C4XIJ3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

573370:DMR RS04220
gene id: 573370:DMR_RS04220
uniprot id: C4XK06
names: Similarity
messages: Belongs to the Lgt family.

573370:DMR RS09905
gene id: 573370:DMR_RS09905
uniprot id: C4XS60
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS16215
gene id: 573370:DMR_RS16215
uniprot id: C4XKI8
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS08520
gene id: 573370:DMR_RS08520
uniprot id: C4XQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

573370:DMR RS07410
gene id: 573370:DMR_RS07410
uniprot id: C4XPA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

573370:DMR RS08110
gene id: 573370:DMR_RS08110
uniprot id: C4XQ56
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS14220
gene id: 573370:DMR_RS14220
uniprot id: C4XHS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS08010
gene id: 573370:DMR_RS08010
uniprot id: C4XPM1
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

573370:DMR RS14570
gene id: 573370:DMR_RS14570
uniprot id: C4XIH2
names: Similarity
messages: Belongs to the peptidase M18 family.

573370:DMR RS04490
gene id: 573370:DMR_RS04490
uniprot id: C4XK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

573370:DMR RS19775
gene id: 573370:DMR_RS19775
uniprot id: C4XPZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

573370:DMR RS19870
gene id: 573370:DMR_RS19870
uniprot id: C4XQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS10330
gene id: 573370:DMR_RS10330
uniprot id: C4XSE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

573370:DMR RS12810
gene id: 573370:DMR_RS12810
uniprot id: C4XUE5
names: Similarity
messages: Belongs to the peptidase M16 family.

573370:DMR RS05590
gene id: 573370:DMR_RS05590
uniprot id: C4XLX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

573370:DMR RS02715
gene id: 573370:DMR_RS02715
uniprot id: C4XIA7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

573370:DMR RS18730
gene id: 573370:DMR_RS18730
uniprot id: C4XNX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

573370:DMR RS12525
gene id: 573370:DMR_RS12525
uniprot id: C4XU88
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573370:DMR RS01815
gene id: 573370:DMR_RS01815
uniprot id: C4XHC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

573370:DMR RS10560
gene id: 573370:DMR_RS10560
uniprot id: C4XSL3
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS11670
gene id: 573370:DMR_RS11670
uniprot id: C4XTD6
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS19450
gene id: 573370:DMR_RS19450
uniprot id: C4XPR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS12075
gene id: 573370:DMR_RS12075
uniprot id: C4XTZ7
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

573370:DMR RS15065
gene id: 573370:DMR_RS15065
uniprot id: C4XIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

573370:DMR RS13635
gene id: 573370:DMR_RS13635
uniprot id: C4XH26
names: Similarity
messages: Belongs to the GSP E family.

573370:DMR RS19810
gene id: 573370:DMR_RS19810
uniprot id: C4XQ03
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

573370:DMR RS07105
gene id: 573370:DMR_RS07105
uniprot id: C4XNQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

573370:DMR RS21855
gene id: 573370:DMR_RS21855
uniprot id: C4XSI5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

573370:DMR RS18635
gene id: 573370:DMR_RS18635
uniprot id: C4XNV4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

573370:DMR RS16120
gene id: 573370:DMR_RS16120
uniprot id: C4XKG9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

573370:DMR RS05320
gene id: 573370:DMR_RS05320
uniprot id: C4XLR9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

573370:DMR RS00440
gene id: 573370:DMR_RS00440
uniprot id: C4XTT0
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS14115
gene id: 573370:DMR_RS14115
uniprot id: C4XHR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

573370:DMR RS16740
gene id: 573370:DMR_RS16740
uniprot id: C4XL87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

573370:DMR RS22410
gene id: 573370:DMR_RS22410
uniprot id: C4XTG0
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS13330
gene id: 573370:DMR_RS13330
uniprot id: C4XGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

573370:DMR RS16900
gene id: 573370:DMR_RS16900
uniprot id: C4XLC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS15225
gene id: 573370:DMR_RS15225
uniprot id: C4XJB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

573370:DMR RS02300
gene id: 573370:DMR_RS02300
uniprot id: C4XI23
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS13750
gene id: 573370:DMR_RS13750
uniprot id: C4XHH7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

573370:DMR RS13275
gene id: 573370:DMR_RS13275
uniprot id: C4XGV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

573370:DMR RS04255
gene id: 573370:DMR_RS04255
uniprot id: C4XK11
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS05480
gene id: 573370:DMR_RS05480
uniprot id: C4XLV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

573370:DMR RS16575
gene id: 573370:DMR_RS16575
uniprot id: C4XL54
names: Similarity
messages: Belongs to the peptidase A24 family.

573370:DMR RS04830
gene id: 573370:DMR_RS04830
uniprot id: C4XL20
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

573370:DMR RS07780
gene id: 573370:DMR_RS07780
uniprot id: C4XPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

573370:DMR RS10015
gene id: 573370:DMR_RS10015
uniprot id: C4XS81
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

573370:DMR RS08625
gene id: 573370:DMR_RS08625
uniprot id: C4XQF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573370:DMR RS09610
gene id: 573370:DMR_RS09610
uniprot id: C4XRH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

573370:DMR RS10555
gene id: 573370:DMR_RS10555
uniprot id: C4XSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

573370:DMR RS13280
gene id: 573370:DMR_RS13280
uniprot id: C4XGV3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

573370:DMR RS11405
gene id: 573370:DMR_RS11405
uniprot id: C4XT82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

573370:DMR RS10550
gene id: 573370:DMR_RS10550
uniprot id: C4XSL1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

573370:DMR RS04785
gene id: 573370:DMR_RS04785
uniprot id: C4XL11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS07665
gene id: 573370:DMR_RS07665
uniprot id: C4XPF7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

573370:DMR RS10020
gene id: 573370:DMR_RS10020
uniprot id: C4XS82
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

573370:DMR RS16495
gene id: 573370:DMR_RS16495
uniprot id: C4XL38
names: Similarity
messages: Belongs to the P(II) protein family.

573370:DMR RS03210
gene id: 573370:DMR_RS03210
uniprot id: C4XJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

573370:DMR RS15025
gene id: 573370:DMR_RS15025
uniprot id: C4XIR3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

573370:DMR RS01030
gene id: 573370:DMR_RS01030
uniprot id: C4XGF6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

573370:DMR RS19860
gene id: 573370:DMR_RS19860
uniprot id: C4XQ14
names: Similarity
messages: Belongs to the universal stress protein A family.

573370:DMR RS17840
gene id: 573370:DMR_RS17840
uniprot id: C4XMZ6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573370:DMR RS19620
gene id: 573370:DMR_RS19620
uniprot id: C4XPV6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573370:DMR RS08585
gene id: 573370:DMR_RS08585
uniprot id: C4XQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

573370:DMR RS06435
gene id: 573370:DMR_RS06435
uniprot id: C4XMU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

573370:DMR RS21920
gene id: 573370:DMR_RS21920
uniprot id: C4XPR0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS00840
gene id: 573370:DMR_RS00840
uniprot id: C4XGB8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS10415
gene id: 573370:DMR_RS10415
uniprot id: C4XS27
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

573370:DMR RS15195
gene id: 573370:DMR_RS15195
uniprot id: C4XJB3
names: Similarity
messages: Belongs to the TPP enzyme family.

573370:DMR RS15075
gene id: 573370:DMR_RS15075
uniprot id: C4XIS3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

573370:DMR RS21830
gene id: 573370:DMR_RS21830
uniprot id: C4XSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

573370:DMR RS08140
gene id: 573370:DMR_RS08140
uniprot id: C4XQ63
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

573370:DMR RS10375
gene id: 573370:DMR_RS10375
uniprot id: C4XSF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

573370:DMR RS08525
gene id: 573370:DMR_RS08525
uniprot id: C4XQD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

573370:DMR RS14695
gene id: 573370:DMR_RS14695
uniprot id: C4XIJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

573370:DMR RS11450
gene id: 573370:DMR_RS11450
uniprot id: C4XT91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

573370:DMR RS17390
gene id: 573370:DMR_RS17390
uniprot id: C4XM81
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

573370:DMR RS12165
gene id: 573370:DMR_RS12165
uniprot id: C4XU15
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

573370:DMR RS18540
gene id: 573370:DMR_RS18540
uniprot id: C4XND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

573370:DMR RS12355
gene id: 573370:DMR_RS12355
uniprot id: C4XU53
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

573370:DMR RS00020
gene id: 573370:DMR_RS00020
uniprot id: C4XT13
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

573370:DMR RS18495
gene id: 573370:DMR_RS18495
uniprot id: C4XNC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

573370:DMR RS08845
gene id: 573370:DMR_RS08845
uniprot id: C4XQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

573370:DMR RS16985
gene id: 573370:DMR_RS16985
uniprot id: C4XLD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

573370:DMR RS02650
gene id: 573370:DMR_RS02650
uniprot id: C4XI94
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS16835
gene id: 573370:DMR_RS16835
uniprot id: C4XLA8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573370:DMR RS02910
gene id: 573370:DMR_RS02910
uniprot id: C4XIU5
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18980
gene id: 573370:DMR_RS18980
uniprot id: C4XP23
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

573370:DMR RS18460
gene id: 573370:DMR_RS18460
uniprot id: C4XNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS11495
gene id: 573370:DMR_RS11495
uniprot id: C4XT99
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS00145
gene id: 573370:DMR_RS00145
uniprot id: C4XT38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

573370:DMR RS10125
gene id: 573370:DMR_RS10125
uniprot id: C4XSA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

573370:DMR RS07715
gene id: 573370:DMR_RS07715
uniprot id: C4XPG3
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10600
gene id: 573370:DMR_RS10600
uniprot id: C4XSM1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS07170
gene id: 573370:DMR_RS07170
uniprot id: C4XNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573370:DMR RS07645
gene id: 573370:DMR_RS07645
uniprot id: C4XPF3
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS21490
gene id: 573370:DMR_RS21490
uniprot id: C4XRX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573370:DMR RS14875
gene id: 573370:DMR_RS14875
uniprot id: C4XIN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573370:DMR RS10045
gene id: 573370:DMR_RS10045
uniprot id: C4XS87
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

573370:DMR RS08590
gene id: 573370:DMR_RS08590
uniprot id: C4XQF0
names: Similarity
messages: Belongs to the GcvT family.

573370:DMR RS12935
gene id: 573370:DMR_RS12935
uniprot id: C4XGN4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

573370:DMR RS00915
gene id: 573370:DMR_RS00915
uniprot id: C4XGD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS18340
gene id: 573370:DMR_RS18340
uniprot id: C4XN94
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

573370:DMR RS08405
gene id: 573370:DMR_RS08405
uniprot id: C4XQB4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

573370:DMR RS05160
gene id: 573370:DMR_RS05160
uniprot id: C4XLN7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

573370:DMR RS13295
gene id: 573370:DMR_RS13295
uniprot id: C4XGV6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

573370:DMR RS10380
gene id: 573370:DMR_RS10380
uniprot id: C4XSF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

573370:DMR RS15680
gene id: 573370:DMR_RS15680
uniprot id: C4XK73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

573370:DMR RS09585
gene id: 573370:DMR_RS09585
uniprot id: C4XRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

573370:DMR RS14850
gene id: 573370:DMR_RS14850
uniprot id: C4XIN3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS12150
gene id: 573370:DMR_RS12150
uniprot id: C4XU12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

573370:DMR RS18575
gene id: 573370:DMR_RS18575
uniprot id: C4XNU2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

573370:DMR RS02220
gene id: 573370:DMR_RS02220
uniprot id: C4XI07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

573370:DMR RS09465
gene id: 573370:DMR_RS09465
uniprot id: C4XRF1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

573370:DMR RS04145
gene id: 573370:DMR_RS04145
uniprot id: C4XJZ1
names: Subcellular Location Annotation
messages: Periplasm

573370:DMR RS21290
gene id: 573370:DMR_RS21290
uniprot id: C4XRT4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS18415
gene id: 573370:DMR_RS18415
uniprot id: C4XNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

573370:DMR RS11475
gene id: 573370:DMR_RS11475
uniprot id: C4XT96
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

573370:DMR RS15655
gene id: 573370:DMR_RS15655
uniprot id: C4XK68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

573370:DMR RS16185
gene id: 573370:DMR_RS16185
uniprot id: C4XKI2
names: Similarity
messages: Belongs to the class-I fumarase family.

573370:DMR RS00320
gene id: 573370:DMR_RS00320
uniprot id: C4XTP0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

573370:DMR RS18485
gene id: 573370:DMR_RS18485
uniprot id: C4XNC2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

573370:DMR RS17045
gene id: 573370:DMR_RS17045
uniprot id: C4XLF1
names: Similarity
messages: Belongs to the peptidase S8 family.

573370:DMR RS10370
gene id: 573370:DMR_RS10370
uniprot id: C4XSF2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

573370:DMR RS02720
gene id: 573370:DMR_RS02720
uniprot id: C4XIA8
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS10155
gene id: 573370:DMR_RS10155
uniprot id: C4XSA9
names: Similarity
messages: Belongs to the UbiD family.

573370:DMR RS04120
gene id: 573370:DMR_RS04120
uniprot id: C4XJY6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

573370:DMR RS01705
gene id: 573370:DMR_RS01705
uniprot id: C4XHA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

573370:DMR RS03675
gene id: 573370:DMR_RS03675
uniprot id: C4XJ90
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

573370:DMR RS00670
gene id: 573370:DMR_RS00670
uniprot id: C4XTL7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS06670
gene id: 573370:DMR_RS06670
uniprot id: C4XNF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

573370:DMR RS22530
gene id: 573370:DMR_RS22530
uniprot id: C4XM33
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS13935
gene id: 573370:DMR_RS13935
uniprot id: C4XHL4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

573370:DMR RS11700
gene id: 573370:DMR_RS11700
uniprot id: C4XTE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

573370:DMR RS14910
gene id: 573370:DMR_RS14910
uniprot id: C4XIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

573370:DMR RS17670
gene id: 573370:DMR_RS17670
uniprot id: C4XMC2
names: Similarity
messages: Belongs to the peptidase C40 family.

573370:DMR RS10705
gene id: 573370:DMR_RS10705
uniprot id: C4XSP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

573370:DMR RS21845
gene id: 573370:DMR_RS21845
uniprot id: C4XSI3
names: Similarity
messages: Belongs to the YkuD family.

573370:DMR RS10950
gene id: 573370:DMR_RS10950
uniprot id: C4XSU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS00355
gene id: 573370:DMR_RS00355
uniprot id: C4XTP7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS14295
gene id: 573370:DMR_RS14295
uniprot id: C4XHV0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS08460
gene id: 573370:DMR_RS08460
uniprot id: C4XQC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

573370:DMR RS21075
gene id: 573370:DMR_RS21075
uniprot id: C4XRP2
names: Similarity
messages: Belongs to the UPF0758 family.

573370:DMR RS13915
gene id: 573370:DMR_RS13915
uniprot id: C4XHL0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

573370:DMR RS02625
gene id: 573370:DMR_RS02625
uniprot id: C4XI89
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS12735
gene id: 573370:DMR_RS12735
uniprot id: C4XUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

573370:DMR RS13260
gene id: 573370:DMR_RS13260
uniprot id: C4XGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

573370:DMR RS07385
gene id: 573370:DMR_RS07385
uniprot id: C4XPA2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573370:DMR RS01445
gene id: 573370:DMR_RS01445
uniprot id: C4XH52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

573370:DMR RS05420
gene id: 573370:DMR_RS05420
uniprot id: C4XLU0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

573370:DMR RS06420
gene id: 573370:DMR_RS06420
uniprot id: C4XMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

573370:DMR RS06340
gene id: 573370:DMR_RS06340
uniprot id: C4XMS3
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

573370:DMR RS13300
gene id: 573370:DMR_RS13300
uniprot id: C4XGV7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

573370:DMR RS06885
gene id: 573370:DMR_RS06885
uniprot id: C4XNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

573370:DMR RS07815
gene id: 573370:DMR_RS07815
uniprot id: C4XPI2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

573370:DMR RS10000
gene id: 573370:DMR_RS10000
uniprot id: C4XS78
names: Similarity
messages: Belongs to the LacAB/RpiB family.

573370:DMR RS15715
gene id: 573370:DMR_RS15715
uniprot id: C4XK89
names: Similarity
messages: Belongs to the PhoU family.

573370:DMR RS12835
gene id: 573370:DMR_RS12835
uniprot id: C4XUF5
names: Similarity
messages: Belongs to the Fur family.

573370:DMR RS18235
gene id: 573370:DMR_RS18235
uniprot id: C4XN73
names: Similarity
messages: Belongs to the PhoH family.

573370:DMR RS16200
gene id: 573370:DMR_RS16200
uniprot id: C4XKI5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

573370:DMR RS07830
gene id: 573370:DMR_RS07830
uniprot id: C4XPI5
names: Similarity
messages: Belongs to the GARS family.

573370:DMR RS05210
gene id: 573370:DMR_RS05210
uniprot id: C4XLP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

573370:DMR RS01170
gene id: 573370:DMR_RS01170
uniprot id: C4XGI4
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS20135
gene id: 573370:DMR_RS20135
uniprot id: C4XQN6
names: Similarity
messages: Belongs to the asparagine synthetase family.

573370:DMR RS15500
gene id: 573370:DMR_RS15500
uniprot id: C4XJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

573370:DMR RS15605
gene id: 573370:DMR_RS15605
uniprot id: C4XJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

573370:DMR RS16190
gene id: 573370:DMR_RS16190
uniprot id: C4XKI3
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

573370:DMR RS08565
gene id: 573370:DMR_RS08565
uniprot id: C4XQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

573370:DMR RS14155
gene id: 573370:DMR_RS14155
uniprot id: C4XHR9
names: Similarity
messages: Belongs to the GSP E family.

573370:DMR RS07205
gene id: 573370:DMR_RS07205
uniprot id: C4XNT2
names: Similarity
messages: Belongs to the peptidase A31 family.

573370:DMR RS05520
gene id: 573370:DMR_RS05520
uniprot id: C4XLW0
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS11140
gene id: 573370:DMR_RS11140
uniprot id: C4XSY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

573370:DMR RS17780
gene id: 573370:DMR_RS17780
uniprot id: C4XMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

573370:DMR RS04855
gene id: 573370:DMR_RS04855
uniprot id: C4XL25
names: Similarity
messages: Belongs to the glutamine synthetase family.

573370:DMR RS15055
gene id: 573370:DMR_RS15055
uniprot id: C4XIR9
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

573370:DMR RS06005
gene id: 573370:DMR_RS06005
uniprot id: C4XMK7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS17340
gene id: 573370:DMR_RS17340
uniprot id: C4XM71
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

573370:DMR RS09300
gene id: 573370:DMR_RS09300
uniprot id: C4XRB8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS12940
gene id: 573370:DMR_RS12940
uniprot id: C4XGN5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

573370:DMR RS05495
gene id: 573370:DMR_RS05495
uniprot id: C4XLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573370:DMR RS01655
gene id: 573370:DMR_RS01655
uniprot id: C4XH90
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573370:DMR RS07875
gene id: 573370:DMR_RS07875
uniprot id: C4XPJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

573370:DMR RS22535
gene id: 573370:DMR_RS22535
uniprot id: C4XM34
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS05600
gene id: 573370:DMR_RS05600
uniprot id: C4XLX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

573370:DMR RS11535
gene id: 573370:DMR_RS11535
uniprot id: C4XTA9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

573370:DMR RS13185
gene id: 573370:DMR_RS13185
uniprot id: C4XGT1
names: Similarity
messages: Belongs to the citrate synthase family.

573370:DMR RS21720
gene id: 573370:DMR_RS21720
uniprot id: C4XS21
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS05655
gene id: 573370:DMR_RS05655
uniprot id: C4XLY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

573370:DMR RS15095
gene id: 573370:DMR_RS15095
uniprot id: C4XIS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

573370:DMR RS21065
gene id: 573370:DMR_RS21065
uniprot id: C4XRP0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

573370:DMR RS01380
gene id: 573370:DMR_RS01380
uniprot id: C4XGM8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS15855
gene id: 573370:DMR_RS15855
uniprot id: C4XKB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS04205
gene id: 573370:DMR_RS04205
uniprot id: C4XK03
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS11410
gene id: 573370:DMR_RS11410
uniprot id: C4XT83
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

573370:DMR RS22150
gene id: 573370:DMR_RS22150
uniprot id: C4XUM4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

573370:DMR RS02185
gene id: 573370:DMR_RS02185
uniprot id: C4XI00
names: Similarity
messages: Belongs to the MreC family.

573370:DMR RS08215
gene id: 573370:DMR_RS08215
uniprot id: C4XQ78
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

573370:DMR RS12920
gene id: 573370:DMR_RS12920
uniprot id: C4XGN1
names: Similarity
messages: Belongs to the threonine synthase family.

573370:DMR RS00360
gene id: 573370:DMR_RS00360
uniprot id: C4XTP8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

573370:DMR RS16950
gene id: 573370:DMR_RS16950
uniprot id: C4XLD1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

573370:DMR RS08185
gene id: 573370:DMR_RS08185
uniprot id: C4XQ72
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

573370:DMR RS01660
gene id: 573370:DMR_RS01660
uniprot id: C4XH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

573370:DMR RS13215
gene id: 573370:DMR_RS13215
uniprot id: C4XGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

573370:DMR RS05785
gene id: 573370:DMR_RS05785
uniprot id: C4XMG2
names: Similarity
messages: Belongs to the P(II) protein family.

573370:DMR RS16165
gene id: 573370:DMR_RS16165
uniprot id: C4XKH8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

573370:DMR RS18070
gene id: 573370:DMR_RS18070
uniprot id: C4XN40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

573370:DMR RS09210
gene id: 573370:DMR_RS09210
uniprot id: C4XRA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573370:DMR RS09475
gene id: 573370:DMR_RS09475
uniprot id: C4XRF3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

573370:DMR RS14110
gene id: 573370:DMR_RS14110
uniprot id: C4XHR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

573370:DMR RS20460
gene id: 573370:DMR_RS20460
uniprot id: C4XQV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

573370:DMR RS02865
gene id: 573370:DMR_RS02865
uniprot id: C4XIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

573370:DMR RS19535
gene id: 573370:DMR_RS19535
uniprot id: C4XPT6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS19930
gene id: 573370:DMR_RS19930
uniprot id: C4XQ28
names: Subcellular Location Annotation
messages: Cell inner membrane

573370:DMR RS02730
gene id: 573370:DMR_RS02730
uniprot id: C4XIB0
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS13165
gene id: 573370:DMR_RS13165
uniprot id: C4XGS7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573370:DMR RS16940
gene id: 573370:DMR_RS16940
uniprot id: C4XLC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

573370:DMR RS18525
gene id: 573370:DMR_RS18525
uniprot id: C4XND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS21190
gene id: 573370:DMR_RS21190
uniprot id: C4XRR4
names: Function
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

573370:DMR RS11645
gene id: 573370:DMR_RS11645
uniprot id: C4XTD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

573370:DMR RS13100
gene id: 573370:DMR_RS13100
uniprot id: C4XGR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS05570
gene id: 573370:DMR_RS05570
uniprot id: C4XLX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

573370:DMR RS08930
gene id: 573370:DMR_RS08930
uniprot id: C4XR47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

573370:DMR RS05255
gene id: 573370:DMR_RS05255
uniprot id: C4XLQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

573370:DMR RS08020
gene id: 573370:DMR_RS08020
uniprot id: C4XPM3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

573370:DMR RS16390
gene id: 573370:DMR_RS16390
uniprot id: C4XKL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

573370:DMR RS12600
gene id: 573370:DMR_RS12600
uniprot id: C4XUA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

573370:DMR RS16965
gene id: 573370:DMR_RS16965
uniprot id: C4XLD4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

573370:DMR RS20945
gene id: 573370:DMR_RS20945
uniprot id: C4XRL7
names: Similarity
messages: Belongs to the Ahb/Nir family.

573370:DMR RS08465
gene id: 573370:DMR_RS08465
uniprot id: C4XQC6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

573370:DMR RS16830
gene id: 573370:DMR_RS16830
uniprot id: C4XLA7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS21085
gene id: 573370:DMR_RS21085
uniprot id: C4XRP4
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS14815
gene id: 573370:DMR_RS14815
uniprot id: C4XIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

573370:DMR RS11055
gene id: 573370:DMR_RS11055
uniprot id: C4XSW5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

573370:DMR RS09420
gene id: 573370:DMR_RS09420
uniprot id: C4XRE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573370:DMR RS04860
gene id: 573370:DMR_RS04860
uniprot id: C4XL26
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS09840
gene id: 573370:DMR_RS09840
uniprot id: C4XS47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

573370:DMR RS14925
gene id: 573370:DMR_RS14925
uniprot id: C4XIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

573370:DMR RS03605
gene id: 573370:DMR_RS03605
uniprot id: C4XJ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

573370:DMR RS05630
gene id: 573370:DMR_RS05630
uniprot id: C4XLY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

573370:DMR RS14130
gene id: 573370:DMR_RS14130
uniprot id: C4XHR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS21270
gene id: 573370:DMR_RS21270
uniprot id: C4XRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

573370:DMR RS20015
gene id: 573370:DMR_RS20015
uniprot id: C4XQ45
names: Similarity
messages: Belongs to the transglycosylase Slt family.

573370:DMR RS20170
gene id: 573370:DMR_RS20170
uniprot id: C4XQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

573370:DMR RS12880
gene id: 573370:DMR_RS12880
uniprot id: C4XUG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

573370:DMR RS11065
gene id: 573370:DMR_RS11065
uniprot id: C4XSW7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

573370:DMR RS16395
gene id: 573370:DMR_RS16395
uniprot id: C4XKL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

573370:DMR RS14700
gene id: 573370:DMR_RS14700
uniprot id: C4XIJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

573370:DMR RS17425
gene id: 573370:DMR_RS17425
uniprot id: C4XM88
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS07190
gene id: 573370:DMR_RS07190
uniprot id: C4XNS9
names: Similarity
messages: Belongs to the peptidase C56 family.

573370:DMR RS10660
gene id: 573370:DMR_RS10660
uniprot id: C4XSN8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

573370:DMR RS02725
gene id: 573370:DMR_RS02725
uniprot id: C4XIA9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS21445
gene id: 573370:DMR_RS21445
uniprot id: C4XRW5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

573370:DMR RS13520
gene id: 573370:DMR_RS13520
uniprot id: C4XH01
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

573370:DMR RS24005
gene id: 573370:DMR_RS24005
uniprot id: C4XRR2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS07085
gene id: 573370:DMR_RS07085
uniprot id: C4XNQ1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

573370:DMR RS01350
gene id: 573370:DMR_RS01350
uniprot id: C4XGL8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS03710
gene id: 573370:DMR_RS03710
uniprot id: C4XJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm

573370:DMR RS20880
gene id: 573370:DMR_RS20880
uniprot id: C4XR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

573370:DMR RS11085
gene id: 573370:DMR_RS11085
uniprot id: C4XSX1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

573370:DMR RS17815
gene id: 573370:DMR_RS17815
uniprot id: C4XMZ1
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

573370:DMR RS07975
gene id: 573370:DMR_RS07975
uniprot id: C4XPL5
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

573370:DMR RS13770
gene id: 573370:DMR_RS13770
uniprot id: C4XHI1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573370:DMR RS03125
gene id: 573370:DMR_RS03125
uniprot id: C4XIY7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

573370:DMR RS12275
gene id: 573370:DMR_RS12275
uniprot id: C4XU38
names: Similarity
messages: Belongs to the UDPGP type 2 family.

573370:DMR RS20040
gene id: 573370:DMR_RS20040
uniprot id: C4XQ52
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS16550
gene id: 573370:DMR_RS16550
uniprot id: C4XL49
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

573370:DMR RS05735
gene id: 573370:DMR_RS05735
uniprot id: C4XME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573370:DMR RS21850
gene id: 573370:DMR_RS21850
uniprot id: C4XSI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS06905
gene id: 573370:DMR_RS06905
uniprot id: C4XNK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS03095
gene id: 573370:DMR_RS03095
uniprot id: C4XIY1
names: Similarity
messages: Belongs to the universal stress protein A family.

573370:DMR RS08920
gene id: 573370:DMR_RS08920
uniprot id: C4XR45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS18295
gene id: 573370:DMR_RS18295
uniprot id: C4XN85
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS20175
gene id: 573370:DMR_RS20175
uniprot id: C4XQP4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS10245
gene id: 573370:DMR_RS10245
uniprot id: C4XSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

573370:DMR RS22140
gene id: 573370:DMR_RS22140
uniprot id: C4XUM2
names: Similarity
messages: Belongs to the transposase 7 family.

573370:DMR RS17565
gene id: 573370:DMR_RS17565
uniprot id: C4XMB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

573370:DMR RS10035
gene id: 573370:DMR_RS10035
uniprot id: C4XS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

573370:DMR RS13055
gene id: 573370:DMR_RS13055
uniprot id: C4XGQ8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS04975
gene id: 573370:DMR_RS04975
uniprot id: C4XLJ4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

573370:DMR RS08770
gene id: 573370:DMR_RS08770
uniprot id: C4XQJ3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

573370:DMR RS08260
gene id: 573370:DMR_RS08260
uniprot id: C4XQ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

573370:DMR RS07710
gene id: 573370:DMR_RS07710
uniprot id: C4XPG2
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS02005
gene id: 573370:DMR_RS02005
uniprot id: C4XHF8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS06320
gene id: 573370:DMR_RS06320
uniprot id: C4XMR9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573370:DMR RS03670
gene id: 573370:DMR_RS03670
uniprot id: C4XJ89
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

573370:DMR RS10650
gene id: 573370:DMR_RS10650
uniprot id: C4XSN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

573370:DMR RS16565
gene id: 573370:DMR_RS16565
uniprot id: C4XL52
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

573370:DMR RS10640
gene id: 573370:DMR_RS10640
uniprot id: C4XSN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

573370:DMR RS13480
gene id: 573370:DMR_RS13480
uniprot id: C4XGZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

573370:DMR RS03165
gene id: 573370:DMR_RS03165
uniprot id: C4XIZ6
names: Similarity
messages: Belongs to the GSP E family.

573370:DMR RS07775
gene id: 573370:DMR_RS07775
uniprot id: C4XPH4
names: Similarity
messages: Belongs to the FeoA family.

573370:DMR RS15120
gene id: 573370:DMR_RS15120
uniprot id: C4XIM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

573370:DMR RS02615
gene id: 573370:DMR_RS02615
uniprot id: C4XI87
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

573370:DMR RS07155
gene id: 573370:DMR_RS07155
uniprot id: C4XNS2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

573370:DMR RS12435
gene id: 573370:DMR_RS12435
uniprot id: C4XU70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS05575
gene id: 573370:DMR_RS05575
uniprot id: C4XIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

573370:DMR RS18050
gene id: 573370:DMR_RS18050
uniprot id: C4XN37
names: Similarity
messages: Belongs to the autoinducer synthase family.

573370:DMR RS08280
gene id: 573370:DMR_RS08280
uniprot id: C4XQ90
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

573370:DMR RS04060
gene id: 573370:DMR_RS04060
uniprot id: C4XJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS05650
gene id: 573370:DMR_RS05650
uniprot id: C4XLY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

573370:DMR RS03205
gene id: 573370:DMR_RS03205
uniprot id: C4XJ03
names: Similarity
messages: Belongs to the GSP E family.

573370:DMR RS15800
gene id: 573370:DMR_RS15800
uniprot id: C4XKA5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS04960
gene id: 573370:DMR_RS04960
uniprot id: C4XLJ1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08605
gene id: 573370:DMR_RS08605
uniprot id: C4XQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

573370:DMR RS16500
gene id: 573370:DMR_RS16500
uniprot id: C4XL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS09875
gene id: 573370:DMR_RS09875
uniprot id: C4XS55
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

573370:DMR RS18100
gene id: 573370:DMR_RS18100
uniprot id: C4XN46
names: Similarity
messages: Belongs to the UPF0251 family.

573370:DMR RS10900
gene id: 573370:DMR_RS10900
uniprot id: C4XST5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

573370:DMR RS15830
gene id: 573370:DMR_RS15830
uniprot id: C4XKB1
names: Similarity
messages: Belongs to the DinB family.

573370:DMR RS03580
gene id: 573370:DMR_RS03580
uniprot id: C4XJ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

573370:DMR RS13405
gene id: 573370:DMR_RS13405
uniprot id: C4XGX8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08025
gene id: 573370:DMR_RS08025
uniprot id: C4XPM4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

573370:DMR RS11640
gene id: 573370:DMR_RS11640
uniprot id: C4XTD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS05615
gene id: 573370:DMR_RS05615
uniprot id: C4XLX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

573370:DMR RS07705
gene id: 573370:DMR_RS07705
uniprot id: C4XPG1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS11625
gene id: 573370:DMR_RS11625
uniprot id: C4XTC7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

573370:DMR RS08210
gene id: 573370:DMR_RS08210
uniprot id: C4XQ77
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

573370:DMR RS04910
gene id: 573370:DMR_RS04910
uniprot id: C4XKR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS05395
gene id: 573370:DMR_RS05395
uniprot id: C4XLT5
names: Similarity
messages: Belongs to the Ahb/Nir family.

573370:DMR RS14710
gene id: 573370:DMR_RS14710
uniprot id: C4XIK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

573370:DMR RS13675
gene id: 573370:DMR_RS13675
uniprot id: C4XH34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

573370:DMR RS17020
gene id: 573370:DMR_RS17020
uniprot id: C4XLE5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

573370:DMR RS20380
gene id: 573370:DMR_RS20380
uniprot id: C4XQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

573370:DMR RS01720
gene id: 573370:DMR_RS01720
uniprot id: C4XHA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS01175
gene id: 573370:DMR_RS01175
uniprot id: C4XGI5
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS15515
gene id: 573370:DMR_RS15515
uniprot id: C4XJP3
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS06665
gene id: 573370:DMR_RS06665
uniprot id: C4XNF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

573370:DMR RS14535
gene id: 573370:DMR_RS14535
uniprot id: C4XIG6
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS03945
gene id: 573370:DMR_RS03945
uniprot id: C4XJV1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18240
gene id: 573370:DMR_RS18240
uniprot id: C4XN74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS20555
gene id: 573370:DMR_RS20555
uniprot id: C4XQX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

573370:DMR RS10655
gene id: 573370:DMR_RS10655
uniprot id: C4XSN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

573370:DMR RS05700
gene id: 573370:DMR_RS05700
uniprot id: C4XLK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

573370:DMR RS10050
gene id: 573370:DMR_RS10050
uniprot id: C4XS88
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

573370:DMR RS02810
gene id: 573370:DMR_RS02810
uniprot id: C4XIC7
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

573370:DMR RS09605
gene id: 573370:DMR_RS09605
uniprot id: C4XRH8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

573370:DMR RS12780
gene id: 573370:DMR_RS12780
uniprot id: C4XUD9
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

573370:DMR RS20050
gene id: 573370:DMR_RS20050
uniprot id: C4XQL9
names: Similarity
messages: Belongs to the peptidase C59 family.

573370:DMR RS05475
gene id: 573370:DMR_RS05475
uniprot id: C4XLV1
names: Similarity
messages: Belongs to the FeoA family.

573370:DMR RS21070
gene id: 573370:DMR_RS21070
uniprot id: C4XRP1
names: Similarity
messages: Belongs to the acylphosphatase family.

573370:DMR RS21090
gene id: 573370:DMR_RS21090
uniprot id: C4XRP5
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08870
gene id: 573370:DMR_RS08870
uniprot id: C4XQL6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

573370:DMR RS20310
gene id: 573370:DMR_RS20310
uniprot id: C4XQS1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

573370:DMR RS00255
gene id: 573370:DMR_RS00255
uniprot id: C4XTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

573370:DMR RS13355
gene id: 573370:DMR_RS13355
uniprot id: C4XGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS12345
gene id: 573370:DMR_RS12345
uniprot id: C4XU51
names: Subcellular Location Annotation
messages: Cytoplasm

573370:DMR RS17385
gene id: 573370:DMR_RS17385
uniprot id: C4XM80
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

573370:DMR RS18670
gene id: 573370:DMR_RS18670
uniprot id: C4XNW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

573370:DMR RS06165
gene id: 573370:DMR_RS06165
uniprot id: C4XMN8
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

573370:DMR RS10565
gene id: 573370:DMR_RS10565
uniprot id: C4XSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

573370:DMR RS03315
gene id: 573370:DMR_RS03315
uniprot id: C4XJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS03910
gene id: 573370:DMR_RS03910
uniprot id: C4XJU4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

573370:DMR RS17230
gene id: 573370:DMR_RS17230
uniprot id: C4XM19
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS02000
gene id: 573370:DMR_RS02000
uniprot id: C4XHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS12825
gene id: 573370:DMR_RS12825
uniprot id: C4XUF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS15765
gene id: 573370:DMR_RS15765
uniprot id: C4XK99
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

573370:DMR RS05500
gene id: 573370:DMR_RS05500
uniprot id: C4XLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573370:DMR RS07840
gene id: 573370:DMR_RS07840
uniprot id: C4XPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS02940
gene id: 573370:DMR_RS02940
uniprot id: C4XIV0
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS21810
gene id: 573370:DMR_RS21810
uniprot id: C4XSH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

573370:DMR RS13505
gene id: 573370:DMR_RS13505
uniprot id: C4XGZ8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

573370:DMR RS18200
gene id: 573370:DMR_RS18200
uniprot id: C4XN66
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573370:DMR RS21260
gene id: 573370:DMR_RS21260
uniprot id: C4XRS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

573370:DMR RS14905
gene id: 573370:DMR_RS14905
uniprot id: C4XIP4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

573370:DMR RS18250
gene id: 573370:DMR_RS18250
uniprot id: C4XN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

573370:DMR RS07620
gene id: 573370:DMR_RS07620
uniprot id: C4XPE8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

573370:DMR RS04195
gene id: 573370:DMR_RS04195
uniprot id: C4XK01
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08300
gene id: 573370:DMR_RS08300
uniprot id: C4XQ94
names: Similarity
messages: Belongs to the peptidase S41A family.

573370:DMR RS13145
gene id: 573370:DMR_RS13145
uniprot id: C4XGS3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS00125
gene id: 573370:DMR_RS00125
uniprot id: C4XT34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

573370:DMR RS01165
gene id: 573370:DMR_RS01165
uniprot id: C4XGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

573370:DMR RS07305
gene id: 573370:DMR_RS07305
uniprot id: C4XP88
names: Similarity
messages: Belongs to the citrate synthase family.

573370:DMR RS02235
gene id: 573370:DMR_RS02235
uniprot id: C4XI10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

573370:DMR RS00385
gene id: 573370:DMR_RS00385
uniprot id: C4XTQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573370:DMR RS04990
gene id: 573370:DMR_RS04990
uniprot id: C4XLJ7
names: Similarity
messages: Belongs to the bacterial glucokinase family.

573370:DMR RS11420
gene id: 573370:DMR_RS11420
uniprot id: C4XT85
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

573370:DMR RS03665
gene id: 573370:DMR_RS03665
uniprot id: C4XJ88
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18695
gene id: 573370:DMR_RS18695
uniprot id: C4XNW6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

573370:DMR RS14900
gene id: 573370:DMR_RS14900
uniprot id: C4XIP3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

573370:DMR RS02640
gene id: 573370:DMR_RS02640
uniprot id: C4XI92
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

573370:DMR RS04895
gene id: 573370:DMR_RS04895
uniprot id: C4XL33
names: Similarity
messages: Belongs to the peptidase S16 family.

573370:DMR RS18225
gene id: 573370:DMR_RS18225
uniprot id: C4XN71
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

573370:DMR RS08330
gene id: 573370:DMR_RS08330
uniprot id: C4XQA0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

573370:DMR RS03815
gene id: 573370:DMR_RS03815
uniprot id: C4XJS7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS06175
gene id: 573370:DMR_RS06175
uniprot id: C4XMP0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

573370:DMR RS12180
gene id: 573370:DMR_RS12180
uniprot id: C4XU18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

573370:DMR RS20430
gene id: 573370:DMR_RS20430
uniprot id: C4XQU5
names: Similarity
messages: Belongs to the MEMO1 family.

573370:DMR RS02415
gene id: 573370:DMR_RS02415
uniprot id: C4XI47
names: Similarity
messages: Belongs to the pyruvate kinase family.

573370:DMR RS05595
gene id: 573370:DMR_RS05595
uniprot id: C4XLX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

573370:DMR RS07420
gene id: 573370:DMR_RS07420
uniprot id: C4XPA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

573370:DMR RS06145
gene id: 573370:DMR_RS06145
uniprot id: C4XMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS10450
gene id: 573370:DMR_RS10450
uniprot id: C4XSJ2
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10395
gene id: 573370:DMR_RS10395
uniprot id: C4XS23
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS12765
gene id: 573370:DMR_RS12765
uniprot id: C4XUD6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

573370:DMR RS17520
gene id: 573370:DMR_RS17520
uniprot id: C4XMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

573370:DMR RS12840
gene id: 573370:DMR_RS12840
uniprot id: C4XUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

573370:DMR RS08150
gene id: 573370:DMR_RS08150
uniprot id: C4XQ65
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

573370:DMR RS10910
gene id: 573370:DMR_RS10910
uniprot id: C4XST7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

573370:DMR RS02405
gene id: 573370:DMR_RS02405
uniprot id: C4XI45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

573370:DMR RS22615
gene id: 573370:DMR_RS22615
uniprot id: C4XPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS13840
gene id: 573370:DMR_RS13840
uniprot id: C4XHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

573370:DMR RS06090
gene id: 573370:DMR_RS06090
uniprot id: C4XMM3
names: Subunit
messages: Heterodimer of a large and a small subunit.

573370:DMR RS20305
gene id: 573370:DMR_RS20305
uniprot id: C4XQS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

573370:DMR RS02510
gene id: 573370:DMR_RS02510
uniprot id: C4XI66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

573370:DMR RS17585
gene id: 573370:DMR_RS17585
uniprot id: C4XMC0
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18950
gene id: 573370:DMR_RS18950
uniprot id: C4XP18
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573370:DMR RS11705
gene id: 573370:DMR_RS11705
uniprot id: C4XTE3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

573370:DMR RS12950
gene id: 573370:DMR_RS12950
uniprot id: C4XGN7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

573370:DMR RS20875
gene id: 573370:DMR_RS20875
uniprot id: C4XR37
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS09115
gene id: 573370:DMR_RS09115
uniprot id: C4XR80
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

573370:DMR RS09870
gene id: 573370:DMR_RS09870
uniprot id: C4XS54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573370:DMR RS14965
gene id: 573370:DMR_RS14965
uniprot id: C4XIQ1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

573370:DMR RS13530
gene id: 573370:DMR_RS13530
uniprot id: C4XH03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

573370:DMR RS09360
gene id: 573370:DMR_RS09360
uniprot id: C4XRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

573370:DMR RS10055
gene id: 573370:DMR_RS10055
uniprot id: C4XS89
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

573370:DMR RS13470
gene id: 573370:DMR_RS13470
uniprot id: C4XGZ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS13600
gene id: 573370:DMR_RS13600
uniprot id: C4XH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

573370:DMR RS01635
gene id: 573370:DMR_RS01635
uniprot id: C4XH86
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

573370:DMR RS15810
gene id: 573370:DMR_RS15810
uniprot id: C4XKA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS10800
gene id: 573370:DMR_RS10800
uniprot id: C4XSR6
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08860
gene id: 573370:DMR_RS08860
uniprot id: C4XQL4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

573370:DMR RS08000
gene id: 573370:DMR_RS08000
uniprot id: C4XPL9
names: Similarity
messages: Belongs to the UPF0166 family.

573370:DMR RS18680
gene id: 573370:DMR_RS18680
uniprot id: C4XNW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

573370:DMR RS10540
gene id: 573370:DMR_RS10540
uniprot id: C4XSK9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS11605
gene id: 573370:DMR_RS11605
uniprot id: C4XTC3
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

573370:DMR RS22220
gene id: 573370:DMR_RS22220
uniprot id: C4XTX7
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS11250
gene id: 573370:DMR_RS11250
uniprot id: C4XT05
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

573370:DMR RS01040
gene id: 573370:DMR_RS01040
uniprot id: C4XGF8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

573370:DMR RS12970
gene id: 573370:DMR_RS12970
uniprot id: C4XGP1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

573370:DMR RS07010
gene id: 573370:DMR_RS07010
uniprot id: C4XNN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

573370:DMR RS01100
gene id: 573370:DMR_RS01100
uniprot id: C4XGH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

573370:DMR RS15235
gene id: 573370:DMR_RS15235
uniprot id: C4XJC1
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

573370:DMR RS20385
gene id: 573370:DMR_RS20385
uniprot id: C4XQT6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

573370:DMR RS09425
gene id: 573370:DMR_RS09425
uniprot id: C4XRE3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

573370:DMR RS06140
gene id: 573370:DMR_RS06140
uniprot id: C4XMN3
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS02500
gene id: 573370:DMR_RS02500
uniprot id: C4XI64
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

573370:DMR RS15455
gene id: 573370:DMR_RS15455
uniprot id: C4XJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

573370:DMR RS10715
gene id: 573370:DMR_RS10715
uniprot id: C4XSP9
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

573370:DMR RS07555
gene id: 573370:DMR_RS07555
uniprot id: C4XPD5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

573370:DMR RS08965
gene id: 573370:DMR_RS08965
uniprot id: C4XR53
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS18760
gene id: 573370:DMR_RS18760
uniprot id: C4XNX9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS12430
gene id: 573370:DMR_RS12430
uniprot id: C4XU69
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

573370:DMR RS12190
gene id: 573370:DMR_RS12190
uniprot id: C4XU20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

573370:DMR RS13380
gene id: 573370:DMR_RS13380
uniprot id: C4XGX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS14670
gene id: 573370:DMR_RS14670
uniprot id: C4XIJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

573370:DMR RS02460
gene id: 573370:DMR_RS02460
uniprot id: C4XI56
names: Similarity
messages: Belongs to the TrpF family.

573370:DMR RS05175
gene id: 573370:DMR_RS05175
uniprot id: C4XLP0
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08485
gene id: 573370:DMR_RS08485
uniprot id: C4XQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

573370:DMR RS12440
gene id: 573370:DMR_RS12440
uniprot id: C4XU71
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS16385
gene id: 573370:DMR_RS16385
uniprot id: C4XKL7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

573370:DMR RS22005
gene id: 573370:DMR_RS22005
uniprot id: C4XUJ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS06845
gene id: 573370:DMR_RS06845
uniprot id: C4XNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

573370:DMR RS20590
gene id: 573370:DMR_RS20590
uniprot id: C4XQY0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

573370:DMR RS12155
gene id: 573370:DMR_RS12155
uniprot id: C4XU13
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

573370:DMR RS20635
gene id: 573370:DMR_RS20635
uniprot id: C4XQY9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS00690
gene id: 573370:DMR_RS00690
uniprot id: C4XG88
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS21115
gene id: 573370:DMR_RS21115
uniprot id: C4XRQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

573370:DMR RS00830
gene id: 573370:DMR_RS00830
uniprot id: C4XGB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

573370:DMR RS03795
gene id: 573370:DMR_RS03795
uniprot id: C4XJS3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

573370:DMR RS20095
gene id: 573370:DMR_RS20095
uniprot id: C4XQM8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

573370:DMR RS16485
gene id: 573370:DMR_RS16485
uniprot id: C4XL36
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

573370:DMR RS20090
gene id: 573370:DMR_RS20090
uniprot id: C4XQM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

573370:DMR RS00635
gene id: 573370:DMR_RS00635
uniprot id: C4XPR0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS16905
gene id: 573370:DMR_RS16905
uniprot id: C4XLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

573370:DMR RS18875
gene id: 573370:DMR_RS18875
uniprot id: C4XP02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS13920
gene id: 573370:DMR_RS13920
uniprot id: C4XHL1
names: Similarity
messages: Belongs to the peptidase S24 family.

573370:DMR RS18855
gene id: 573370:DMR_RS18855
uniprot id: C4XNZ8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS21795
gene id: 573370:DMR_RS21795
uniprot id: C4XSH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

573370:DMR RS01225
gene id: 573370:DMR_RS01225
uniprot id: C4XGJ4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

573370:DMR RS18675
gene id: 573370:DMR_RS18675
uniprot id: C4XNW2
names: Similarity
messages: Belongs to the MotB family.

573370:DMR RS06260
gene id: 573370:DMR_RS06260
uniprot id: C4XMQ7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS02350
gene id: 573370:DMR_RS02350
uniprot id: C4XI34
names: Similarity
messages: Belongs to the CobH/CbiC family.

573370:DMR RS22745
gene id: 573370:DMR_RS22745
uniprot id: C4XKN2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS06910
gene id: 573370:DMR_RS06910
uniprot id: C4XNK9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

573370:DMR RS03045
gene id: 573370:DMR_RS03045
uniprot id: C4XIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

573370:DMR RS15550
gene id: 573370:DMR_RS15550
uniprot id: C4XJP9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

573370:DMR RS18420
gene id: 573370:DMR_RS18420
uniprot id: C4XNA9
names: Subcellular Location Annotation
messages: Periplasm

573370:DMR RS13535
gene id: 573370:DMR_RS13535
uniprot id: C4XH04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

573370:DMR RS22255
gene id: 573370:DMR_RS22255
uniprot id: C4XHZ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573370:DMR RS05935
gene id: 573370:DMR_RS05935
uniprot id: C4XMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

573370:DMR RS05690
gene id: 573370:DMR_RS05690
uniprot id: C4XLK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

573370:DMR RS09715
gene id: 573370:DMR_RS09715
uniprot id: C4XRK0
names: Similarity
messages: Belongs to the P(II) protein family.

573370:DMR RS03970
gene id: 573370:DMR_RS03970
uniprot id: C4XJV6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

573370:DMR RS20925
gene id: 573370:DMR_RS20925
uniprot id: C4XRL2
names: Similarity
messages: Belongs to the NodU/CmcH family.

573370:DMR RS21030
gene id: 573370:DMR_RS21030
uniprot id: C4XRN3
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS16540
gene id: 573370:DMR_RS16540
uniprot id: C4XL47
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

573370:DMR RS05135
gene id: 573370:DMR_RS05135
uniprot id: C4XLN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

573370:DMR RS13190
gene id: 573370:DMR_RS13190
uniprot id: C4XGT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

573370:DMR RS05915
gene id: 573370:DMR_RS05915
uniprot id: C4XMI9
names: Similarity
messages: Belongs to the universal stress protein A family.

573370:DMR RS09505
gene id: 573370:DMR_RS09505
uniprot id: C4XRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

573370:DMR RS07595
gene id: 573370:DMR_RS07595
uniprot id: C4XPE3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS17190
gene id: 573370:DMR_RS17190
uniprot id: C4XM06
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

573370:DMR RS11310
gene id: 573370:DMR_RS11310
uniprot id: C4XT55
names: Similarity
messages: Belongs to the LOG family.

573370:DMR RS09120
gene id: 573370:DMR_RS09120
uniprot id: C4XR81
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS03160
gene id: 573370:DMR_RS03160
uniprot id: C4XIZ5
names: Similarity
messages: Belongs to the GSP E family.

573370:DMR RS09990
gene id: 573370:DMR_RS09990
uniprot id: C4XS76
names: Similarity
messages: Belongs to the FBPase class 2 family.

573370:DMR RS08075
gene id: 573370:DMR_RS08075
uniprot id: C4XPN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

573370:DMR RS05945
gene id: 573370:DMR_RS05945
uniprot id: C4XMJ5
names: Subunit
messages: Heterodimer of a large and a small subunit.

573370:DMR RS19790
gene id: 573370:DMR_RS19790
uniprot id: C4XPZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

573370:DMR RS18800
gene id: 573370:DMR_RS18800
uniprot id: C4XNY7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

573370:DMR RS12135
gene id: 573370:DMR_RS12135
uniprot id: C4XU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

573370:DMR RS00050
gene id: 573370:DMR_RS00050
uniprot id: C4XT19
names: Similarity
messages: Belongs to the band 7/mec-2 family.

573370:DMR RS19280
gene id: 573370:DMR_RS19280
uniprot id: C4XP80
names: Similarity
messages: Belongs to the heat shock protein 70 family.

573370:DMR RS10065
gene id: 573370:DMR_RS10065
uniprot id: C4XS91
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

573370:DMR RS19840
gene id: 573370:DMR_RS19840
uniprot id: C4XQ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

573370:DMR RS00275
gene id: 573370:DMR_RS00275
uniprot id: C4XTN2
names: Similarity
messages: Belongs to the asparagine synthetase family.

573370:DMR RS16490
gene id: 573370:DMR_RS16490
uniprot id: C4XL37
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

573370:DMR RS03825
gene id: 573370:DMR_RS03825
uniprot id: C4XJS9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS11460
gene id: 573370:DMR_RS11460
uniprot id: C4XT93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

573370:DMR RS19925
gene id: 573370:DMR_RS19925
uniprot id: C4XQ27
names: Similarity
messages: Belongs to the peptidase C40 family.

573370:DMR RS14975
gene id: 573370:DMR_RS14975
uniprot id: C4XIQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

573370:DMR RS10930
gene id: 573370:DMR_RS10930
uniprot id: C4XSU1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS12890
gene id: 573370:DMR_RS12890
uniprot id: C4XUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

573370:DMR RS19835
gene id: 573370:DMR_RS19835
uniprot id: C4XQ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

573370:DMR RS18450
gene id: 573370:DMR_RS18450
uniprot id: C4XNB5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

573370:DMR RS19235
gene id: 573370:DMR_RS19235
uniprot id: C4XP82
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573370:DMR RS02605
gene id: 573370:DMR_RS02605
uniprot id: C4XI85
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

573370:DMR RS10485
gene id: 573370:DMR_RS10485
uniprot id: C4XSJ9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

573370:DMR RS10315
gene id: 573370:DMR_RS10315
uniprot id: C4XSE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

573370:DMR RS09810
gene id: 573370:DMR_RS09810
uniprot id: C4XS41
names: Similarity
messages: Belongs to the LOG family.

573370:DMR RS06345
gene id: 573370:DMR_RS06345
uniprot id: C4XMS4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

573370:DMR RS17495
gene id: 573370:DMR_RS17495
uniprot id: C4XMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

573370:DMR RS10790
gene id: 573370:DMR_RS10790
uniprot id: C4XSR4
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS08145
gene id: 573370:DMR_RS08145
uniprot id: C4XQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

573370:DMR RS17145
gene id: 573370:DMR_RS17145
uniprot id: C4XLH4
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS02135
gene id: 573370:DMR_RS02135
uniprot id: C4XHZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS18255
gene id: 573370:DMR_RS18255
uniprot id: C4XN77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

573370:DMR RS11400
gene id: 573370:DMR_RS11400
uniprot id: C4XT81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

573370:DMR RS01760
gene id: 573370:DMR_RS01760
uniprot id: C4XHA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS09705
gene id: 573370:DMR_RS09705
uniprot id: C4XRJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

573370:DMR RS06150
gene id: 573370:DMR_RS06150
uniprot id: C4XMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS03695
gene id: 573370:DMR_RS03695
uniprot id: C4XJ94
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS14880
gene id: 573370:DMR_RS14880
uniprot id: C4XIN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573370:DMR RS09315
gene id: 573370:DMR_RS09315
uniprot id: C4XRC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

573370:DMR RS13375
gene id: 573370:DMR_RS13375
uniprot id: C4XGX2
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS11160
gene id: 573370:DMR_RS11160
uniprot id: C4XSY6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

573370:DMR RS18490
gene id: 573370:DMR_RS18490
uniprot id: C4XNC3
names: Subunit
messages: Homodimer.

573370:DMR RS03660
gene id: 573370:DMR_RS03660
uniprot id: C4XJ87
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573370:DMR RS18440
gene id: 573370:DMR_RS18440
uniprot id: C4XNB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

573370:DMR RS18430
gene id: 573370:DMR_RS18430
uniprot id: C4XNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

573370:DMR RS05635
gene id: 573370:DMR_RS05635
uniprot id: C4XLY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

573370:DMR RS06460
gene id: 573370:DMR_RS06460
uniprot id: C4XMU9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

573370:DMR RS04800
gene id: 573370:DMR_RS04800
uniprot id: C4XL14
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

573370:DMR RS02200
gene id: 573370:DMR_RS02200
uniprot id: C4XI03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

573370:DMR RS11135
gene id: 573370:DMR_RS11135
uniprot id: C4XSY1
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

573370:DMR RS08655
gene id: 573370:DMR_RS08655
uniprot id: C4XQG3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573370:DMR RS05185
gene id: 573370:DMR_RS05185
uniprot id: C4XLP2
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS15940
gene id: 573370:DMR_RS15940
uniprot id: C4XKD3
names: Similarity
messages: Belongs to the GSP E family.

573370:DMR RS14990
gene id: 573370:DMR_RS14990
uniprot id: C4XIQ6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

573370:DMR RS16375
gene id: 573370:DMR_RS16375
uniprot id: C4XKL5
names: Similarity
messages: Belongs to the UPF0102 family.

573370:DMR RS07880
gene id: 573370:DMR_RS07880
uniprot id: C4XPJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS16140
gene id: 573370:DMR_RS16140
uniprot id: C4XKH3
names: Similarity
messages: Belongs to the catalase family.

573370:DMR RS21545
gene id: 573370:DMR_RS21545
uniprot id: C4XRY5
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS03085
gene id: 573370:DMR_RS03085
uniprot id: C4XIX9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

573370:DMR RS00215
gene id: 573370:DMR_RS00215
uniprot id: C4XT09
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

573370:DMR RS00170
gene id: 573370:DMR_RS00170
uniprot id: C4XT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS02710
gene id: 573370:DMR_RS02710
uniprot id: C4XIA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS16770
gene id: 573370:DMR_RS16770
uniprot id: C4XL93
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

573370:DMR RS03560
gene id: 573370:DMR_RS03560
uniprot id: C4XJ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

573370:DMR RS11125
gene id: 573370:DMR_RS11125
uniprot id: C4XSX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

573370:DMR RS06880
gene id: 573370:DMR_RS06880
uniprot id: C4XNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

573370:DMR RS14225
gene id: 573370:DMR_RS14225
uniprot id: C4XHT0
names: Subcellular Location Annotation
messages: Cell inner membrane

573370:DMR RS16880
gene id: 573370:DMR_RS16880
uniprot id: C4XLB7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS17435
gene id: 573370:DMR_RS17435
uniprot id: C4XM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

573370:DMR RS13730
gene id: 573370:DMR_RS13730
uniprot id: C4XH08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

573370:DMR RS19290
gene id: 573370:DMR_RS19290
uniprot id: C4XPN7
names: Similarity
messages: Belongs to the FeoA family.

573370:DMR RS05565
gene id: 573370:DMR_RS05565
uniprot id: C4XLW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

573370:DMR RS04970
gene id: 573370:DMR_RS04970
uniprot id: C4XLJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573370:DMR RS18385
gene id: 573370:DMR_RS18385
uniprot id: C4XNA2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

573370:DMR RS03610
gene id: 573370:DMR_RS03610
uniprot id: C4XJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

573370:DMR RS04140
gene id: 573370:DMR_RS04140
uniprot id: C4XJZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

573370:DMR RS00390
gene id: 573370:DMR_RS00390
uniprot id: C4XTQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573370:DMR RS15675
gene id: 573370:DMR_RS15675
uniprot id: C4XK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

573370:DMR RS10755
gene id: 573370:DMR_RS10755
uniprot id: C4XSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

573370:DMR RS16005
gene id: 573370:DMR_RS16005
uniprot id: C4XKE6
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS01135
gene id: 573370:DMR_RS01135
uniprot id: C4XGH7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS15465
gene id: 573370:DMR_RS15465
uniprot id: C4XJN3
names: Similarity
messages: Belongs to the RecJ family.

573370:DMR RS14035
gene id: 573370:DMR_RS14035
uniprot id: C4XHP9
names: Similarity
messages: Belongs to the Skp family.

573370:DMR RS07890
gene id: 573370:DMR_RS07890
uniprot id: C4XPJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

573370:DMR RS13945
gene id: 573370:DMR_RS13945
uniprot id: C4XHL6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

573370:DMR RS05695
gene id: 573370:DMR_RS05695
uniprot id: C4XLK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

573370:DMR RS16425
gene id: 573370:DMR_RS16425
uniprot id: C4XKM5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS14580
gene id: 573370:DMR_RS14580
uniprot id: C4XIH4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

573370:DMR RS17895
gene id: 573370:DMR_RS17895
uniprot id: C4XN07
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

573370:DMR RS04025
gene id: 573370:DMR_RS04025
uniprot id: C4XJW7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS08505
gene id: 573370:DMR_RS08505
uniprot id: C4XQD4
names: Similarity
messages: Belongs to the PhoU family.

573370:DMR RS17765
gene id: 573370:DMR_RS17765
uniprot id: C4XMY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

573370:DMR RS18935
gene id: 573370:DMR_RS18935
uniprot id: C4XP15
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS19670
gene id: 573370:DMR_RS19670
uniprot id: C4XPX5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

573370:DMR RS17755
gene id: 573370:DMR_RS17755
uniprot id: C4XMX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

573370:DMR RS17205
gene id: 573370:DMR_RS17205
uniprot id: C4XM13
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

573370:DMR RS18090
gene id: 573370:DMR_RS18090
uniprot id: C4XN44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

573370:DMR RS07995
gene id: 573370:DMR_RS07995
uniprot id: C4XPL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

573370:DMR RS17560
gene id: 573370:DMR_RS17560
uniprot id: C4XMB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

573370:DMR RS18655
gene id: 573370:DMR_RS18655
uniprot id: C4XNV8
names: Similarity
messages: Belongs to the UPF0434 family.

573370:DMR RS16380
gene id: 573370:DMR_RS16380
uniprot id: C4XKL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

573370:DMR RS04795
gene id: 573370:DMR_RS04795
uniprot id: C4XL13
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

573370:DMR RS00735
gene id: 573370:DMR_RS00735
uniprot id: C4XG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS09400
gene id: 573370:DMR_RS09400
uniprot id: C4XRD8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18650
gene id: 573370:DMR_RS18650
uniprot id: C4XNV7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573370:DMR RS07240
gene id: 573370:DMR_RS07240
uniprot id: C4XNT9
names: Similarity
messages: Belongs to the MotB family.

573370:DMR RS06075
gene id: 573370:DMR_RS06075
uniprot id: C4XMM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS03740
gene id: 573370:DMR_RS03740
uniprot id: C4XJA3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

573370:DMR RS01980
gene id: 573370:DMR_RS01980
uniprot id: C4XHF3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

573370:DMR RS06390
gene id: 573370:DMR_RS06390
uniprot id: C4XMT4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

573370:DMR RS03105
gene id: 573370:DMR_RS03105
uniprot id: C4XIY3
names: Similarity
messages: Belongs to the RutC family.

573370:DMR RS15070
gene id: 573370:DMR_RS15070
uniprot id: C4XIS2
names: Subcellular Location Annotation
messages: Secreted

573370:DMR RS16560
gene id: 573370:DMR_RS16560
uniprot id: C4XL51
names: Similarity
messages: Belongs to the hyi family.

573370:DMR RS10280
gene id: 573370:DMR_RS10280
uniprot id: C4XSD4
names: Similarity
messages: Belongs to the thioredoxin family.

573370:DMR RS20525
gene id: 573370:DMR_RS20525
uniprot id: C4XQW8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS03355
gene id: 573370:DMR_RS03355
uniprot id: C4XJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

573370:DMR RS02595
gene id: 573370:DMR_RS02595
uniprot id: C4XI83
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

573370:DMR RS05680
gene id: 573370:DMR_RS05680
uniprot id: C4XLZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

573370:DMR RS07120
gene id: 573370:DMR_RS07120
uniprot id: C4XNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

573370:DMR RS07090
gene id: 573370:DMR_RS07090
uniprot id: C4XNQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

573370:DMR RS07545
gene id: 573370:DMR_RS07545
uniprot id: C4XPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

573370:DMR RS12745
gene id: 573370:DMR_RS12745
uniprot id: C4XUD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

573370:DMR RS09625
gene id: 573370:DMR_RS09625
uniprot id: C4XRI2
names: Similarity
messages: Belongs to the HupF/HypC family.

573370:DMR RS11300
gene id: 573370:DMR_RS11300
uniprot id: C4XT53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

573370:DMR RS09570
gene id: 573370:DMR_RS09570
uniprot id: C4XRH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

573370:DMR RS20410
gene id: 573370:DMR_RS20410
uniprot id: C4XQU1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS01155
gene id: 573370:DMR_RS01155
uniprot id: C4XGI1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS21220
gene id: 573370:DMR_RS21220
uniprot id: C4XRS0
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS14610
gene id: 573370:DMR_RS14610
uniprot id: C4XII0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

573370:DMR RS15210
gene id: 573370:DMR_RS15210
uniprot id: C4XJB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

573370:DMR RS18810
gene id: 573370:DMR_RS18810
uniprot id: C4XNY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS00010
gene id: 573370:DMR_RS00010
uniprot id: C4XT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

573370:DMR RS08205
gene id: 573370:DMR_RS08205
uniprot id: C4XQ76
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

573370:DMR RS01245
gene id: 573370:DMR_RS01245
uniprot id: C4XGJ8
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS12290
gene id: 573370:DMR_RS12290
uniprot id: C4XU41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

573370:DMR RS07960
gene id: 573370:DMR_RS07960
uniprot id: C4XPL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

573370:DMR RS12635
gene id: 573370:DMR_RS12635
uniprot id: C4XUB0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

573370:DMR RS18780
gene id: 573370:DMR_RS18780
uniprot id: C4XNY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

573370:DMR RS08395
gene id: 573370:DMR_RS08395
uniprot id: C4XQB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

573370:DMR RS15110
gene id: 573370:DMR_RS15110
uniprot id: C4XIM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

573370:DMR RS02250
gene id: 573370:DMR_RS02250
uniprot id: C4XI13
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS09800
gene id: 573370:DMR_RS09800
uniprot id: C4XS39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

573370:DMR RS15245
gene id: 573370:DMR_RS15245
uniprot id: C4XJC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

573370:DMR RS00870
gene id: 573370:DMR_RS00870
uniprot id: C4XGC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

573370:DMR RS12475
gene id: 573370:DMR_RS12475
uniprot id: C4XU78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573370:DMR RS08940
gene id: 573370:DMR_RS08940
uniprot id: C4XR49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

573370:DMR RS16170
gene id: 573370:DMR_RS16170
uniprot id: C4XKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS14885
gene id: 573370:DMR_RS14885
uniprot id: C4XIP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

573370:DMR RS01990
gene id: 573370:DMR_RS01990
uniprot id: C4XHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573370:DMR RS15405
gene id: 573370:DMR_RS15405
uniprot id: C4XJL3
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS18425
gene id: 573370:DMR_RS18425
uniprot id: C4XNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

573370:DMR RS05215
gene id: 573370:DMR_RS05215
uniprot id: C4XLP8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573370:DMR RS10465
gene id: 573370:DMR_RS10465
uniprot id: C4XSJ5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS21540
gene id: 573370:DMR_RS21540
uniprot id: C4XRY4
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS22510
gene id: 573370:DMR_RS22510
uniprot id: C4XJI8
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS07825
gene id: 573370:DMR_RS07825
uniprot id: C4XPI4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

573370:DMR RS08125
gene id: 573370:DMR_RS08125
uniprot id: C4XQ59
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

573370:DMR RS13210
gene id: 573370:DMR_RS13210
uniprot id: C4XGT6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

573370:DMR RS04625
gene id: 573370:DMR_RS04625
uniprot id: C4XKV1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS05675
gene id: 573370:DMR_RS05675
uniprot id: C4XLZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

573370:DMR RS13630
gene id: 573370:DMR_RS13630
uniprot id: C4XH25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

573370:DMR RS04805
gene id: 573370:DMR_RS04805
uniprot id: C4XL15
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573370:DMR RS15835
gene id: 573370:DMR_RS15835
uniprot id: C4XKB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

573370:DMR RS19805
gene id: 573370:DMR_RS19805
uniprot id: C4XQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

573370:DMR RS14825
gene id: 573370:DMR_RS14825
uniprot id: C4XIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

573370:DMR RS04395
gene id: 573370:DMR_RS04395
uniprot id: C4XK42
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS09220
gene id: 573370:DMR_RS09220
uniprot id: C4XRA2
names: Similarity
messages: Belongs to the FeoA family.

573370:DMR RS15660
gene id: 573370:DMR_RS15660
uniprot id: C4XK69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

573370:DMR RS02100
gene id: 573370:DMR_RS02100
uniprot id: C4XHY3
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

573370:DMR RS11190
gene id: 573370:DMR_RS11190
uniprot id: C4XSZ2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

573370:DMR RS20240
gene id: 573370:DMR_RS20240
uniprot id: C4XQQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS21555
gene id: 573370:DMR_RS21555
uniprot id: C4XRY7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

573370:DMR RS08490
gene id: 573370:DMR_RS08490
uniprot id: C4XQD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

573370:DMR RS13385
gene id: 573370:DMR_RS13385
uniprot id: C4XGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS19800
gene id: 573370:DMR_RS19800
uniprot id: C4XQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

573370:DMR RS19845
gene id: 573370:DMR_RS19845
uniprot id: C4XQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

573370:DMR RS02470
gene id: 573370:DMR_RS02470
uniprot id: C4XI58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS13870
gene id: 573370:DMR_RS13870
uniprot id: C4XHK1
names: Similarity
messages: Belongs to the PhoH family.

573370:DMR RS09335
gene id: 573370:DMR_RS09335
uniprot id: C4XRC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS06360
gene id: 573370:DMR_RS06360
uniprot id: C4XMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

573370:DMR RS05220
gene id: 573370:DMR_RS05220
uniprot id: C4XLP9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573370:DMR RS04500
gene id: 573370:DMR_RS04500
uniprot id: C4XKM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

573370:DMR RS22750
gene id: 573370:DMR_RS22750
uniprot id: C4XKV5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573370:DMR RS01190
gene id: 573370:DMR_RS01190
uniprot id: C4XGI8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

573370:DMR RS05330
gene id: 573370:DMR_RS05330
uniprot id: C4XLS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

573370:DMR RS17360
gene id: 573370:DMR_RS17360
uniprot id: C4XM75
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

573370:DMR RS01180
gene id: 573370:DMR_RS01180
uniprot id: C4XGI6
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

573370:DMR RS18290
gene id: 573370:DMR_RS18290
uniprot id: C4XN84
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18790
gene id: 573370:DMR_RS18790
uniprot id: C4XNY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

573370:DMR RS16400
gene id: 573370:DMR_RS16400
uniprot id: C4XKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

573370:DMR RS08635
gene id: 573370:DMR_RS08635
uniprot id: C4XQF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573370:DMR RS15060
gene id: 573370:DMR_RS15060
uniprot id: C4XIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

573370:DMR RS20060
gene id: 573370:DMR_RS20060
uniprot id: C4XQM1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

573370:DMR RS13490
gene id: 573370:DMR_RS13490
uniprot id: C4XGZ5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

573370:DMR RS10625
gene id: 573370:DMR_RS10625
uniprot id: C4XSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

573370:DMR RS06900
gene id: 573370:DMR_RS06900
uniprot id: C4XNK7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

573370:DMR RS19725
gene id: 573370:DMR_RS19725
uniprot id: C4XPZ0
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS11395
gene id: 573370:DMR_RS11395
uniprot id: C4XT80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

573370:DMR RS00085
gene id: 573370:DMR_RS00085
uniprot id: C4XT26
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573370:DMR RS10350
gene id: 573370:DMR_RS10350
uniprot id: C4XSE8
names: Similarity
messages: Belongs to the YggT family.

573370:DMR RS05640
gene id: 573370:DMR_RS05640
uniprot id: C4XLY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

573370:DMR RS13305
gene id: 573370:DMR_RS13305
uniprot id: C4XGV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

573370:DMR RS14370
gene id: 573370:DMR_RS14370
uniprot id: C4XHX1
names: Subunit
messages: Heterodimer of a large and a small subunit.

573370:DMR RS18720
gene id: 573370:DMR_RS18720
uniprot id: C4XNX1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

573370:DMR RS02805
gene id: 573370:DMR_RS02805
uniprot id: C4XIC6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

573370:DMR RS12405
gene id: 573370:DMR_RS12405
uniprot id: C4XU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

573370:DMR RS00075
gene id: 573370:DMR_RS00075
uniprot id: C4XT24
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

573370:DMR RS25615
gene id: 573370:DMR_RS25615
uniprot id: C4XGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

573370:DMR RS16860
gene id: 573370:DMR_RS16860
uniprot id: C4XLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
messages: Cytoplasm

573370:DMR RS00680
gene id: 573370:DMR_RS00680
uniprot id: C4XTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

573370:DMR RS12070
gene id: 573370:DMR_RS12070
uniprot id: C4XTZ6
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS02110
gene id: 573370:DMR_RS02110
uniprot id: C4XHY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

573370:DMR RS02230
gene id: 573370:DMR_RS02230
uniprot id: C4XI09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

573370:DMR RS18715
gene id: 573370:DMR_RS18715
uniprot id: C4XNX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

573370:DMR RS15665
gene id: 573370:DMR_RS15665
uniprot id: C4XK70
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS18665
gene id: 573370:DMR_RS18665
uniprot id: C4XNW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

573370:DMR RS19085
gene id: 573370:DMR_RS19085
uniprot id: C4XP42
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573370:DMR RS07730
gene id: 573370:DMR_RS07730
uniprot id: C4XPG6
names: Similarity
messages: Belongs to the LarC family.

573370:DMR RS20265
gene id: 573370:DMR_RS20265
uniprot id: C4XQR2
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10905
gene id: 573370:DMR_RS10905
uniprot id: C4XST6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

573370:DMR RS09860
gene id: 573370:DMR_RS09860
uniprot id: C4XS52
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

573370:DMR RS10580
gene id: 573370:DMR_RS10580
uniprot id: C4XSL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

573370:DMR RS02430
gene id: 573370:DMR_RS02430
uniprot id: C4XI50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

573370:DMR RS06135
gene id: 573370:DMR_RS06135
uniprot id: C4XMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

573370:DMR RS00500
gene id: 573370:DMR_RS00500
uniprot id: C4XPR0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

573370:DMR RS07210
gene id: 573370:DMR_RS07210
uniprot id: C4XNT3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

573370:DMR RS02765
gene id: 573370:DMR_RS02765
uniprot id: C4XIB7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS02180
gene id: 573370:DMR_RS02180
uniprot id: C4XHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

573370:DMR RS19695
gene id: 573370:DMR_RS19695
uniprot id: C4XPY1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573370:DMR RS05705
gene id: 573370:DMR_RS05705
uniprot id: C4XLK3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

573370:DMR RS02265
gene id: 573370:DMR_RS02265
uniprot id: C4XI16
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

573370:DMR RS20190
gene id: 573370:DMR_RS20190
uniprot id: C4XQP7
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS14705
gene id: 573370:DMR_RS14705
uniprot id: C4XIJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

573370:DMR RS13960
gene id: 573370:DMR_RS13960
uniprot id: C4XHM5
names: Similarity
messages: Belongs to the ros/MucR family.

573370:DMR RS12995
gene id: 573370:DMR_RS12995
uniprot id: C4XGP6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573370:DMR RS12375
gene id: 573370:DMR_RS12375
uniprot id: C4XU57
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

573370:DMR RS06355
gene id: 573370:DMR_RS06355
uniprot id: C4XMS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

573370:DMR RS12975
gene id: 573370:DMR_RS12975
uniprot id: C4XGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

573370:DMR RS02450
gene id: 573370:DMR_RS02450
uniprot id: C4XI54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

573370:DMR RS00785
gene id: 573370:DMR_RS00785
uniprot id: C4XGA7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

573370:DMR RS12370
gene id: 573370:DMR_RS12370
uniprot id: C4XU56
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

573370:DMR RS14355
gene id: 573370:DMR_RS14355
uniprot id: C4XHW6
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS18300
gene id: 573370:DMR_RS18300
uniprot id: C4XN86
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

573370:DMR RS19830
gene id: 573370:DMR_RS19830
uniprot id: C4XQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

573370:DMR RS08190
gene id: 573370:DMR_RS08190
uniprot id: C4XQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

573370:DMR RS07245
gene id: 573370:DMR_RS07245
uniprot id: C4XNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

573370:DMR RS02875
gene id: 573370:DMR_RS02875
uniprot id: C4XIT8
names: Similarity
messages: Belongs to the glutamine synthetase family.

573370:DMR RS09175
gene id: 573370:DMR_RS09175
uniprot id: C4XR92
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

573370:DMR RS00005
gene id: 573370:DMR_RS00005
uniprot id: C4XT10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

573370:DMR RS10185
gene id: 573370:DMR_RS10185
uniprot id: C4XSB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

573370:DMR RS07215
gene id: 573370:DMR_RS07215
uniprot id: C4XNT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

573370:DMR RS13345
gene id: 573370:DMR_RS13345
uniprot id: C4XGW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS09040
gene id: 573370:DMR_RS09040
uniprot id: C4XR67
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

573370:DMR RS15780
gene id: 573370:DMR_RS15780
uniprot id: C4XKA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

573370:DMR RS06185
gene id: 573370:DMR_RS06185
uniprot id: C4XMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573370:DMR RS11345
gene id: 573370:DMR_RS11345
uniprot id: C4XT63
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

573370:DMR RS06215
gene id: 573370:DMR_RS06215
uniprot id: C4XMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

573370:DMR RS10100
gene id: 573370:DMR_RS10100
uniprot id: C4XS98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

573370:DMR RS17760
gene id: 573370:DMR_RS17760
uniprot id: C4XMY0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS21365
gene id: 573370:DMR_RS21365
uniprot id: C4XRU9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS05200
gene id: 573370:DMR_RS05200
uniprot id: C4XLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

573370:DMR RS15640
gene id: 573370:DMR_RS15640
uniprot id: C4XK65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

573370:DMR RS08005
gene id: 573370:DMR_RS08005
uniprot id: C4XPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

573370:DMR RS10545
gene id: 573370:DMR_RS10545
uniprot id: C4XSL0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS08425
gene id: 573370:DMR_RS08425
uniprot id: C4XQB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS04400
gene id: 573370:DMR_RS04400
uniprot id: C4XK43
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS09020
gene id: 573370:DMR_RS09020
uniprot id: C4XR64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

573370:DMR RS03585
gene id: 573370:DMR_RS03585
uniprot id: C4XJ72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

573370:DMR RS08925
gene id: 573370:DMR_RS08925
uniprot id: C4XR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

573370:DMR RS11105
gene id: 573370:DMR_RS11105
uniprot id: C4XSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

573370:DMR RS04210
gene id: 573370:DMR_RS04210
uniprot id: C4XK04
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10735
gene id: 573370:DMR_RS10735
uniprot id: C4XSQ3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

573370:DMR RS14820
gene id: 573370:DMR_RS14820
uniprot id: C4XIM0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573370:DMR RS11970
gene id: 573370:DMR_RS11970
uniprot id: C4XTK4
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS10690
gene id: 573370:DMR_RS10690
uniprot id: C4XSP4
names: Similarity
messages: Belongs to the leucine-binding protein family.

573370:DMR RS12560
gene id: 573370:DMR_RS12560
uniprot id: C4XU95
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

573370:DMR RS08850
gene id: 573370:DMR_RS08850
uniprot id: C4XQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573370:DMR RS13225
gene id: 573370:DMR_RS13225
uniprot id: C4XGU2
names: Similarity
messages: Belongs to the peptidase M20A family.

573370:DMR RS02210
gene id: 573370:DMR_RS02210
uniprot id: C4XI05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

573370:DMR RS06170
gene id: 573370:DMR_RS06170
uniprot id: C4XMN9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

573370:DMR RS12095
gene id: 573370:DMR_RS12095
uniprot id: C4XU01
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

573370:DMR RS05605
gene id: 573370:DMR_RS05605
uniprot id: C4XLX7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

573370:DMR RS06770
gene id: 573370:DMR_RS06770
uniprot id: C4XNH9
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTCGAG-3' and cleaves after C-1.
messages: Belongs to the XhoI type II restriction endonuclease family.

573370:DMR RS08130
gene id: 573370:DMR_RS08130
uniprot id: C4XQ61
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

573370:DMR RS15670
gene id: 573370:DMR_RS15670
uniprot id: C4XK71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

573370:DMR RS15160
gene id: 573370:DMR_RS15160
uniprot id: C4XJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

573370:DMR RS10445
gene id: 573370:DMR_RS10445
uniprot id: C4XSJ1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS14920
gene id: 573370:DMR_RS14920
uniprot id: C4XIP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

573370:DMR RS09865
gene id: 573370:DMR_RS09865
uniprot id: C4XS53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573370:DMR RS10620
gene id: 573370:DMR_RS10620
uniprot id: C4XSM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

573370:DMR RS17415
gene id: 573370:DMR_RS17415
uniprot id: C4XM86
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS21125
gene id: 573370:DMR_RS21125
uniprot id: C4XRQ2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

573370:DMR RS22480
gene id: 573370:DMR_RS22480
uniprot id: C4XHM4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

573370:DMR RS14625
gene id: 573370:DMR_RS14625
uniprot id: C4XII3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

573370:DMR RS00370
gene id: 573370:DMR_RS00370
uniprot id: C4XTQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

573370:DMR RS07980
gene id: 573370:DMR_RS07980
uniprot id: C4XPL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573370:DMR RS15590
gene id: 573370:DMR_RS15590
uniprot id: C4XJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

573370:DMR RS12130
gene id: 573370:DMR_RS12130
uniprot id: C4XU08
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573370:DMR RS09770
gene id: 573370:DMR_RS09770
uniprot id: C4XS33
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

573370:DMR RS01840
gene id: 573370:DMR_RS01840
uniprot id: C4XHC5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS11725
gene id: 573370:DMR_RS11725
uniprot id: C4XTE7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

573370:DMR RS05620
gene id: 573370:DMR_RS05620
uniprot id: C4XLY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

573370:DMR RS21700
gene id: 573370:DMR_RS21700
uniprot id: C4XS17
names: Similarity
messages: Belongs to the SfsA family.

573370:DMR RS01010
gene id: 573370:DMR_RS01010
uniprot id: C4XGF2
names: Similarity
messages: Belongs to the hemerythrin family.

573370:DMR RS17990
gene id: 573370:DMR_RS17990
uniprot id: C4XN25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

573370:DMR RS18945
gene id: 573370:DMR_RS18945
uniprot id: C4XP17
names: Similarity
messages: Belongs to the polysaccharide synthase family.

573370:DMR RS13775
gene id: 573370:DMR_RS13775
uniprot id: C4XHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

573370:DMR RS05660
gene id: 573370:DMR_RS05660
uniprot id: C4XLY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

573370:DMR RS15610
gene id: 573370:DMR_RS15610
uniprot id: C4XJR0
names: Similarity
messages: Belongs to the universal stress protein A family.

573370:DMR RS17600
gene id: 573370:DMR_RS17600
uniprot id: C4XMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

573370:DMR RS05725
gene id: 573370:DMR_RS05725
uniprot id: C4XME2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

573370:DMR RS02245
gene id: 573370:DMR_RS02245
uniprot id: C4XI12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

573370:DMR RS12625
gene id: 573370:DMR_RS12625
uniprot id: C4XUA8
names: Subcellular Location Annotation
messages: Cell inner membrane

573370:DMR RS10700
gene id: 573370:DMR_RS10700
uniprot id: C4XSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

573370:DMR RS07885
gene id: 573370:DMR_RS07885
uniprot id: C4XPJ5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

573370:DMR RS08910
gene id: 573370:DMR_RS08910
uniprot id: C4XR43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

573370:DMR RS01385
gene id: 573370:DMR_RS01385
uniprot id: C4XGM9
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS06525
gene id: 573370:DMR_RS06525
uniprot id: C4XMW1
names: Subcellular Location Annotation
messages: Membrane

573370:DMR RS12495
gene id: 573370:DMR_RS12495
uniprot id: C4XU82
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

573370:DMR RS20950
gene id: 573370:DMR_RS20950
uniprot id: C4XRL8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573370:DMR RS21815
gene id: 573370:DMR_RS21815
uniprot id: C4XSH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

573370:DMR RS16160
gene id: 573370:DMR_RS16160
uniprot id: C4XKH7
names: Subcellular Location Annotation
messages: Membrane