559295:KLTH0A06842g
gene id: 559295:KLTH0A06842g
uniprot id: C5DC06
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

559295:KLTH0D09020g
gene id: 559295:KLTH0D09020g
uniprot id: C5DGX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

559295:KLTH0C08316g
gene id: 559295:KLTH0C08316g
uniprot id: C5DED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

559295:KLTH0F04334g
gene id: 559295:KLTH0F04334g
uniprot id: C5DKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

559295:KLTH0F04532g
gene id: 559295:KLTH0F04532g
uniprot id: C5DKG7
names: Similarity
messages: Belongs to the LST4 family.

559295:KLTH0H15224g
gene id: 559295:KLTH0H15224g
uniprot id: C5E3P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

559295:KLTH0G00814g
gene id: 559295:KLTH0G00814g
uniprot id: C5DLH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

559295:KLTH0F17292g
gene id: 559295:KLTH0F17292g
uniprot id: C5DJL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

559295:KLTH0E04114g
gene id: 559295:KLTH0E04114g
uniprot id: C5DHG3
names: Similarity
messages: Belongs to the MBF1 family.

559295:KLTH0H12320g
gene id: 559295:KLTH0H12320g
uniprot id: C5E3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Mitochondrion

559295:KLTH0B08140g
gene id: 559295:KLTH0B08140g
uniprot id: C5DD43
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E15774g
gene id: 559295:KLTH0E15774g
uniprot id: C5DIW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

559295:KLTH0B08624g
gene id: 559295:KLTH0B08624g
uniprot id: C5DD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

559295:KLTH0H02134g
gene id: 559295:KLTH0H02134g
uniprot id: C5E249
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0E08580g
gene id: 559295:KLTH0E08580g
uniprot id: C5DI01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

559295:KLTH0D03058g
gene id: 559295:KLTH0D03058g
uniprot id: C5DG79
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

559295:KLTH0H01276g
gene id: 559295:KLTH0H01276g
uniprot id: C5E210
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E03850g
gene id: 559295:KLTH0E03850g
uniprot id: C5DHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

559295:KLTH0G07700g
gene id: 559295:KLTH0G07700g
uniprot id: C5DMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

559295:KLTH0G06292g
gene id: 559295:KLTH0G06292g
uniprot id: C5DM63
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0F17138g
gene id: 559295:KLTH0F17138g
uniprot id: C5DJK3
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

559295:KLTH0G16368g
gene id: 559295:KLTH0G16368g
uniprot id: C5DNE8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

559295:KLTH0H10450g
gene id: 559295:KLTH0H10450g
uniprot id: C5E352
names: Similarity
messages: Belongs to the VPS26 family.

559295:KLTH0D17468g
gene id: 559295:KLTH0D17468g
uniprot id: C5DFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

559295:KLTH0D06402g
gene id: 559295:KLTH0D06402g
uniprot id: C5DGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

559295:KLTH0B03146g
gene id: 559295:KLTH0B03146g
uniprot id: C5DCH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

559295:KLTH0B00110g
gene id: 559295:KLTH0B00110g
uniprot id: C5DC55
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G09372g
gene id: 559295:KLTH0G09372g
uniprot id: C5DMJ1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A05896g
gene id: 559295:KLTH0A05896g
uniprot id: C5DBW6
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

559295:KLTH0G05390g
gene id: 559295:KLTH0G05390g
uniprot id: C5DM25
names: Similarity
messages: Belongs to the VPS29 family.

559295:KLTH0B01408g
gene id: 559295:KLTH0B01408g
uniprot id: C5DCA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

559295:KLTH0G11044g
gene id: 559295:KLTH0G11044g
uniprot id: C5DMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
messages: Mitochondrion inner membrane

559295:KLTH0D00396g
gene id: 559295:KLTH0D00396g
uniprot id: C5DFW1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H04554g
gene id: 559295:KLTH0H04554g
uniprot id: C5E2F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

559295:KLTH0A00440g
gene id: 559295:KLTH0A00440g
uniprot id: C5DB82
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C08096g
gene id: 559295:KLTH0C08096g
uniprot id: C5DEC6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

559295:KLTH0F11638g
gene id: 559295:KLTH0F11638g
uniprot id: C5DLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

559295:KLTH0F02090g
gene id: 559295:KLTH0F02090g
uniprot id: C5DK63
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

559295:KLTH0H04158g
gene id: 559295:KLTH0H04158g
uniprot id: C5E2E0
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0G00572g
gene id: 559295:KLTH0G00572g
uniprot id: C5DLG6
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

559295:KLTH0D07502g
gene id: 559295:KLTH0D07502g
uniprot id: C5DGR6
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

559295:KLTH0F02618g
gene id: 559295:KLTH0F02618g
uniprot id: C5DK87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

559295:KLTH0H07964g
gene id: 559295:KLTH0H07964g
uniprot id: C5E2V3
names: Similarity
messages: Belongs to the MNN1/MNT family.

559295:KLTH0A04004g
gene id: 559295:KLTH0A04004g
uniprot id: C5DBN1
names: Similarity
messages: Belongs to the aspartokinase family.

559295:KLTH0B07282g
gene id: 559295:KLTH0B07282g
uniprot id: C5DD05
names: Similarity
messages: Belongs to the importin alpha family.

559295:KLTH0D00770g
gene id: 559295:KLTH0D00770g
uniprot id: C5DFX7
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

559295:KLTH0G12452g
gene id: 559295:KLTH0G12452g
uniprot id: C5DMX6
names: Similarity
messages: Belongs to the VPS37 family.

559295:KLTH0F18348g
gene id: 559295:KLTH0F18348g
uniprot id: C5DJQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

559295:KLTH0G17754g
gene id: 559295:KLTH0G17754g
uniprot id: C5DNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

559295:KLTH0D04136g
gene id: 559295:KLTH0D04136g
uniprot id: C5DGC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

559295:KLTH0E07304g
gene id: 559295:KLTH0E07304g
uniprot id: C5DHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

559295:KLTH0F08954g
gene id: 559295:KLTH0F08954g
uniprot id: C5DL05
names: Similarity
messages: Belongs to the peptidase M16 family.

559295:KLTH0H01232g
gene id: 559295:KLTH0H01232g
uniprot id: C5E208
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

559295:KLTH0D01980g
gene id: 559295:KLTH0D01980g
uniprot id: C5DG30
names: Subcellular Location Annotation
messages: Mitochondrion

559295:KLTH0C10208g
gene id: 559295:KLTH0C10208g
uniprot id: C5DEL4
names: Similarity
messages: Belongs to the GET4 family.

559295:KLTH0C02684g
gene id: 559295:KLTH0C02684g
uniprot id: C5DDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

559295:KLTH0A07722g
gene id: 559295:KLTH0A07722g
uniprot id: C5DC46
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0D04378g
gene id: 559295:KLTH0D04378g
uniprot id: C5DGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

559295:KLTH0D06380g
gene id: 559295:KLTH0D06380g
uniprot id: C5DGL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

559295:KLTH0F18656g
gene id: 559295:KLTH0F18656g
uniprot id: C5DJS1
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

559295:KLTH0E01826g
gene id: 559295:KLTH0E01826g
uniprot id: C5DH70
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0C05610g
gene id: 559295:KLTH0C05610g
uniprot id: C5DE20
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

559295:KLTH0G13596g
gene id: 559295:KLTH0G13596g
uniprot id: C5DN25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GEP5 family.
messages: Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins (By similarity).
messages: Mitochondrion

559295:KLTH0F17600g
gene id: 559295:KLTH0F17600g
uniprot id: C5DJM3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F17116g
gene id: 559295:KLTH0F17116g
uniprot id: C5DJK2
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

559295:KLTH0B03344g
gene id: 559295:KLTH0B03344g
uniprot id: C5DCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

559295:KLTH0D17644g
gene id: 559295:KLTH0D17644g
uniprot id: C5DFT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
messages: Nucleus

559295:KLTH0A02772g
gene id: 559295:KLTH0A02772g
uniprot id: C5DBH9
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

559295:KLTH0D14564g
gene id: 559295:KLTH0D14564g
uniprot id: C5DFF0
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

559295:KLTH0A06996g
gene id: 559295:KLTH0A06996g
uniprot id: C5DC13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

559295:KLTH0D13398g
gene id: 559295:KLTH0D13398g
uniprot id: C5DF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: centromere

559295:KLTH0H04202g
gene id: 559295:KLTH0H04202g
uniprot id: C5E2E2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

559295:KLTH0G05434g
gene id: 559295:KLTH0G05434g
uniprot id: C5DM26
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

559295:KLTH0F00880g
gene id: 559295:KLTH0F00880g
uniprot id: C5DK09
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

559295:KLTH0H13420g
gene id: 559295:KLTH0H13420g
uniprot id: C5E3G8
names: Similarity
messages: Belongs to the RNR ribonuclease family.

559295:KLTH0C01826g
gene id: 559295:KLTH0C01826g
uniprot id: C5DDK9
names: Subcellular Location Annotation
messages: Peroxisome membrane

559295:KLTH0C08118g
gene id: 559295:KLTH0C08118g
uniprot id: C5DEC7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

559295:KLTH0A02068g
gene id: 559295:KLTH0A02068g
uniprot id: C5DBF0
names: Similarity
messages: Belongs to the peptidase M67A family.

559295:KLTH0C02310g
gene id: 559295:KLTH0C02310g
uniprot id: C5DDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

559295:KLTH0E06138g
gene id: 559295:KLTH0E06138g
uniprot id: C5DHQ1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E08118g
gene id: 559295:KLTH0E08118g
uniprot id: C5DHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

559295:KLTH0G15818g
gene id: 559295:KLTH0G15818g
uniprot id: C5DNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

559295:KLTH0F07920g
gene id: 559295:KLTH0F07920g
uniprot id: C5DKV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

559295:KLTH0H01540g
gene id: 559295:KLTH0H01540g
uniprot id: C5E222
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

559295:KLTH0H08492g
gene id: 559295:KLTH0H08492g
uniprot id: C5E2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

559295:KLTH0C06468g
gene id: 559295:KLTH0C06468g
uniprot id: C5DE58
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

559295:KLTH0F03938g
gene id: 559295:KLTH0F03938g
uniprot id: C5DKE2
names: Similarity
messages: Belongs to the MNN1/MNT family.

559295:KLTH0C08514g
gene id: 559295:KLTH0C08514g
uniprot id: C5DEE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.

559295:KLTH0D15026g
gene id: 559295:KLTH0D15026g
uniprot id: C5DFH0
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

559295:KLTH0G09504g
gene id: 559295:KLTH0G09504g
uniprot id: C5DMJ7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E12606g
gene id: 559295:KLTH0E12606g
uniprot id: C5DIH7
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

559295:KLTH0F19844g
gene id: 559295:KLTH0F19844g
uniprot id: C5DJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

559295:KLTH0F09658g
gene id: 559295:KLTH0F09658g
uniprot id: C5DL36
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0D09328g
gene id: 559295:KLTH0D09328g
uniprot id: C5DGY7
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0H14982g
gene id: 559295:KLTH0H14982g
uniprot id: C5E3N3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

559295:KLTH0B09548g
gene id: 559295:KLTH0B09548g
uniprot id: C5DDA3
names: Similarity
messages: Belongs to the ELP6 family.

559295:KLTH0H01034g
gene id: 559295:KLTH0H01034g
uniprot id: C5E202
names: Function
names: Similarity
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Monomer.

559295:KLTH0H13640g
gene id: 559295:KLTH0H13640g
uniprot id: C5E3H6
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

559295:KLTH0G02354g
gene id: 559295:KLTH0G02354g
uniprot id: C5DLP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

559295:KLTH0G16346g
gene id: 559295:KLTH0G16346g
uniprot id: C5DNE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

559295:KLTH0E06446g
gene id: 559295:KLTH0E06446g
uniprot id: C5DHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

559295:KLTH0E10934g
gene id: 559295:KLTH0E10934g
uniprot id: C5DIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane
messages: Peroxisome membrane

559295:KLTH0G00968g
gene id: 559295:KLTH0G00968g
uniprot id: C5DLI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0H04070g
gene id: 559295:KLTH0H04070g
uniprot id: C5E2D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

559295:KLTH0H08338g
gene id: 559295:KLTH0H08338g
uniprot id: C5E2W9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

559295:KLTH0B09064g
gene id: 559295:KLTH0B09064g
uniprot id: C5DD81
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

559295:KLTH0B00330g
gene id: 559295:KLTH0B00330g
uniprot id: C5DC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0D07480g
gene id: 559295:KLTH0D07480g
uniprot id: C5DGR5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

559295:KLTH0A05082g
gene id: 559295:KLTH0A05082g
uniprot id: C5DBS9
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0E11660g
gene id: 559295:KLTH0E11660g
uniprot id: C5DID5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

559295:KLTH0D02970g
gene id: 559295:KLTH0D02970g
uniprot id: C5DG75
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F12474g
gene id: 559295:KLTH0F12474g
uniprot id: C5DLE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

559295:KLTH0D10340g
gene id: 559295:KLTH0D10340g
uniprot id: C5DEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

559295:KLTH0G01848g
gene id: 559295:KLTH0G01848g
uniprot id: C5DLM4
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

559295:KLTH0H00462g
gene id: 559295:KLTH0H00462g
uniprot id: C5E1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0H02156g
gene id: 559295:KLTH0H02156g
uniprot id: C5E250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0E14300g
gene id: 559295:KLTH0E14300g
uniprot id: C5DIQ2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0F15136g
gene id: 559295:KLTH0F15136g
uniprot id: C5DJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0D13046g
gene id: 559295:KLTH0D13046g
uniprot id: C5DF84
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0A03872g
gene id: 559295:KLTH0A03872g
uniprot id: C5DBM5
names: Similarity
messages: Belongs to the TPA1 family.

559295:KLTH0H03872g
gene id: 559295:KLTH0H03872g
uniprot id: C5E2C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

559295:KLTH0F14520g
gene id: 559295:KLTH0F14520g
uniprot id: C5DJ92
names: Similarity
messages: Belongs to the RRP15 family.

559295:KLTH0F02464g
gene id: 559295:KLTH0F02464g
uniprot id: C5DK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

559295:KLTH0E02618g
gene id: 559295:KLTH0E02618g
uniprot id: C5DHA2
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0C08470g
gene id: 559295:KLTH0C08470g
uniprot id: C5DEE2
names: Similarity
messages: Belongs to the PPP phosphatase family.

559295:KLTH0B01056g
gene id: 559295:KLTH0B01056g
uniprot id: C5DC88
names: Similarity
messages: Belongs to the MOG1 family.

559295:KLTH0C02486g
gene id: 559295:KLTH0C02486g
uniprot id: C5DDN7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

559295:KLTH0F04180g
gene id: 559295:KLTH0F04180g
uniprot id: C5DKF2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G16984g
gene id: 559295:KLTH0G16984g
uniprot id: C5DNH1
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F01056g
gene id: 559295:KLTH0F01056g
uniprot id: C5DK17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0H06490g
gene id: 559295:KLTH0H06490g
uniprot id: C5E2N8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

559295:KLTH0G13662g
gene id: 559295:KLTH0G13662g
uniprot id: C5DN28
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

559295:KLTH0D15114g
gene id: 559295:KLTH0D15114g
uniprot id: C5DFH4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

559295:KLTH0B05896g
gene id: 559295:KLTH0B05896g
uniprot id: C5DCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

559295:KLTH0H08206g
gene id: 559295:KLTH0H08206g
uniprot id: C5E2W3
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

559295:KLTH0B05522g
gene id: 559295:KLTH0B05522g
uniprot id: C5DCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

559295:KLTH0E09416g
gene id: 559295:KLTH0E09416g
uniprot id: C5DI36
names: Similarity
messages: Belongs to the CCDC25 family.

559295:KLTH0G19404g
gene id: 559295:KLTH0G19404g
uniprot id: C5DNS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0F15774g
gene id: 559295:KLTH0F15774g
uniprot id: C5DJE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

559295:KLTH0E06424g
gene id: 559295:KLTH0E06424g
uniprot id: C5DHR1
names: Similarity
messages: Belongs to the GCN1 family.

559295:KLTH0F12870g
gene id: 559295:KLTH0F12870g
uniprot id: C5DJ23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

559295:KLTH0E01892g
gene id: 559295:KLTH0E01892g
uniprot id: C5DH73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

559295:KLTH0E02156g
gene id: 559295:KLTH0E02156g
uniprot id: C5DH85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

559295:KLTH0F15994g
gene id: 559295:KLTH0F15994g
uniprot id: C5DJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

559295:KLTH0E00550g
gene id: 559295:KLTH0E00550g
uniprot id: C5DH14
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D09548g
gene id: 559295:KLTH0D09548g
uniprot id: C5DGZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

559295:KLTH0A07238g
gene id: 559295:KLTH0A07238g
uniprot id: C5DC24
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

559295:KLTH0D04554g
gene id: 559295:KLTH0D04554g
uniprot id: C5DGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

559295:KLTH0C09614g
gene id: 559295:KLTH0C09614g
uniprot id: C5DEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

559295:KLTH0C01804g
gene id: 559295:KLTH0C01804g
uniprot id: C5DDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTC6 family.
messages: May be involved in telomere capping.
messages: Membrane

559295:KLTH0E11638g
gene id: 559295:KLTH0E11638g
uniprot id: C5DID4
names: Similarity
messages: Belongs to the alkaline phosphatase family.

559295:KLTH0E10406g
gene id: 559295:KLTH0E10406g
uniprot id: C5DI80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0H13376g
gene id: 559295:KLTH0H13376g
uniprot id: C5E3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0G01936g
gene id: 559295:KLTH0G01936g
uniprot id: C5DLM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

559295:KLTH0F04070g
gene id: 559295:KLTH0F04070g
uniprot id: C5DKE7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0H02552g
gene id: 559295:KLTH0H02552g
uniprot id: C5E268
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC4 family.
messages: Mitochondrion intermembrane space
messages: The twin Cx9C motifs are involved in the recognition by the mitochondrial disulfide relay system.

559295:KLTH0B07238g
gene id: 559295:KLTH0B07238g
uniprot id: C5DD03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0D02662g
gene id: 559295:KLTH0D02662g
uniprot id: C5DG61
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D06050g
gene id: 559295:KLTH0D06050g
uniprot id: C5DGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

559295:KLTH0E09614g
gene id: 559295:KLTH0E09614g
uniprot id: C5DI45
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

559295:KLTH0E12826g
gene id: 559295:KLTH0E12826g
uniprot id: C5DII7
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

559295:KLTH0D06204g
gene id: 559295:KLTH0D06204g
uniprot id: C5DGL1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

559295:KLTH0G19558g
gene id: 559295:KLTH0G19558g
uniprot id: C5DNS9
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

559295:KLTH0F05104g
gene id: 559295:KLTH0F05104g
uniprot id: C5DKJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S64 family.
messages: Cell membrane
messages: Component of the plasma membrane SPS (SSY1-PTR3-SSY5) amino acid sensor complex.
messages: Protease component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2. Catalyzes the activation of these transcription factors, which are synthesized as latent cytoplasmic precursors, by proteolytic removal of an N-terminal inhibitory domain containing cytoplasmic retention motifs. SSY5 binds as an inactive protease complex to STP1. In response to extracellular amino acids and dependent on the other SPS-sensor components, the inhibitory propeptide is induced to dissociate, and thereby enables the catalytic domain to process STP1.

559295:KLTH0B09834g
gene id: 559295:KLTH0B09834g
uniprot id: C5DDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

559295:KLTH0E16588g
gene id: 559295:KLTH0E16588g
uniprot id: C5DJ04
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G01166g
gene id: 559295:KLTH0G01166g
uniprot id: C5DLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE10 family.
messages: Component of the mitochondria-localized RNase mitochondrial RNA-processing (RNase MRP) composed of one single RNA encoded by the NME1 gene and at least 31 proteins. Absent in the nucleus-localized RNase MRP (NuMRP).
messages: Involved in spore wall assembly. May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria.
messages: Mitochondrion

559295:KLTH0H13398g
gene id: 559295:KLTH0H13398g
uniprot id: C5E3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0E11528g
gene id: 559295:KLTH0E11528g
uniprot id: C5DIC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of UBP8 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

559295:KLTH0H03696g
gene id: 559295:KLTH0H03696g
uniprot id: C5E2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

559295:KLTH0D09746g
gene id: 559295:KLTH0D09746g
uniprot id: C5DEU1
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0D11000g
gene id: 559295:KLTH0D11000g
uniprot id: C5DEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
messages: Membrane
messages: Preautophagosomal structure membrane

559295:KLTH0D09790g
gene id: 559295:KLTH0D09790g
uniprot id: C5DEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

559295:KLTH0E01628g
gene id: 559295:KLTH0E01628g
uniprot id: C5DH62
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

559295:KLTH0E07216g
gene id: 559295:KLTH0E07216g
uniprot id: C5DHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

559295:KLTH0E08822g
gene id: 559295:KLTH0E08822g
uniprot id: C5DI12
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

559295:KLTH0G06314g
gene id: 559295:KLTH0G06314g
uniprot id: C5DM64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

559295:KLTH0B03828g
gene id: 559295:KLTH0B03828g
uniprot id: C5DCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

559295:KLTH0C07590g
gene id: 559295:KLTH0C07590g
uniprot id: C5DEA4
names: Similarity
messages: Belongs to the WrbA family.

559295:KLTH0E12408g
gene id: 559295:KLTH0E12408g
uniprot id: C5DIG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

559295:KLTH0B05148g
gene id: 559295:KLTH0B05148g
uniprot id: C5DCR2
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

559295:KLTH0D04158g
gene id: 559295:KLTH0D04158g
uniprot id: C5DGC4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D06864g
gene id: 559295:KLTH0D06864g
uniprot id: C5DGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

559295:KLTH0D05126g
gene id: 559295:KLTH0D05126g
uniprot id: C5DGG4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

559295:KLTH0C02442g
gene id: 559295:KLTH0C02442g
uniprot id: C5DDN5
names: Similarity
messages: Belongs to the activator 1 small subunits family.

559295:KLTH0B09944g
gene id: 559295:KLTH0B09944g
uniprot id: C5DDC0
names: Similarity
messages: Belongs to the peptidase C19 family.

559295:KLTH0C05566g
gene id: 559295:KLTH0C05566g
uniprot id: C5DE18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

559295:KLTH0G14124g
gene id: 559295:KLTH0G14124g
uniprot id: C5DN48
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C03586g
gene id: 559295:KLTH0C03586g
uniprot id: C5DDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: telomere

559295:KLTH0H11924g
gene id: 559295:KLTH0H11924g
uniprot id: C5E3B3
names: Similarity
messages: Belongs to the lysophospholipase family.

559295:KLTH0G04488g
gene id: 559295:KLTH0G04488g
uniprot id: C5DLY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

559295:KLTH0A03850g
gene id: 559295:KLTH0A03850g
uniprot id: C5DBM4
names: Similarity
messages: Belongs to the complex I LYR family.

559295:KLTH0D05258g
gene id: 559295:KLTH0D05258g
uniprot id: C5DGH0
names: Similarity
messages: Belongs to the PdxS/SNZ family.

559295:KLTH0B03894g
gene id: 559295:KLTH0B03894g
uniprot id: C5DCK9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D13530g
gene id: 559295:KLTH0D13530g
uniprot id: C5DFA5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

559295:KLTH0E15048g
gene id: 559295:KLTH0E15048g
uniprot id: C5DIT5
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

559295:KLTH0F06996g
gene id: 559295:KLTH0F06996g
uniprot id: C5DKS0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

559295:KLTH0B05500g
gene id: 559295:KLTH0B05500g
uniprot id: C5DCS8
names: Similarity
messages: Belongs to the Tom22 family.

559295:KLTH0B05324g
gene id: 559295:KLTH0B05324g
uniprot id: C5DCS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

559295:KLTH0G01276g
gene id: 559295:KLTH0G01276g
uniprot id: C5DLJ8
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

559295:KLTH0H06578g
gene id: 559295:KLTH0H06578g
uniprot id: C5E2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F04290g
gene id: 559295:KLTH0F04290g
uniprot id: C5DKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

559295:KLTH0F14894g
gene id: 559295:KLTH0F14894g
uniprot id: C5DJA7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0E04268g
gene id: 559295:KLTH0E04268g
uniprot id: C5DHH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

559295:KLTH0B03498g
gene id: 559295:KLTH0B03498g
uniprot id: C5DCJ2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B07172g
gene id: 559295:KLTH0B07172g
uniprot id: C5DD00
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

559295:KLTH0D00946g
gene id: 559295:KLTH0D00946g
uniprot id: C5DFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

559295:KLTH0H15488g
gene id: 559295:KLTH0H15488g
uniprot id: C5E3Q4
names: Similarity
messages: Belongs to the SUN family.

559295:KLTH0C11264g
gene id: 559295:KLTH0C11264g
uniprot id: C5DEQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0H13354g
gene id: 559295:KLTH0H13354g
uniprot id: C5E3G5
names: Similarity
messages: Belongs to the peptidase C19 family.

559295:KLTH0E16544g
gene id: 559295:KLTH0E16544g
uniprot id: C5DJ02
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

559295:KLTH0G03058g
gene id: 559295:KLTH0G03058g
uniprot id: C5DLS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

559295:KLTH0E11946g
gene id: 559295:KLTH0E11946g
uniprot id: C5DIE8
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

559295:KLTH0G04664g
gene id: 559295:KLTH0G04664g
uniprot id: C5DLZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

559295:KLTH0F08536g
gene id: 559295:KLTH0F08536g
uniprot id: C5DKY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

559295:KLTH0G07612g
gene id: 559295:KLTH0G07612g
uniprot id: C5DMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP9 family.
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
messages: nucleolus

559295:KLTH0H08888g
gene id: 559295:KLTH0H08888g
uniprot id: C5E2Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

559295:KLTH0G13354g
gene id: 559295:KLTH0G13354g
uniprot id: C5DN14
names: Similarity
messages: Belongs to the FMO family.

559295:KLTH0D11352g
gene id: 559295:KLTH0D11352g
uniprot id: C5DF10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM44 family.
messages: Bud neck

559295:KLTH0F12320g
gene id: 559295:KLTH0F12320g
uniprot id: C5DLE2
names: Similarity
messages: Belongs to the TOP6A family.

559295:KLTH0D15774g
gene id: 559295:KLTH0D15774g
uniprot id: C5DFK1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0G09460g
gene id: 559295:KLTH0G09460g
uniprot id: C5DMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

559295:KLTH0D03740g
gene id: 559295:KLTH0D03740g
uniprot id: C5DGA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

559295:KLTH0E04466g
gene id: 559295:KLTH0E04466g
uniprot id: C5DHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

559295:KLTH0D00506g
gene id: 559295:KLTH0D00506g
uniprot id: C5DFW5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D16962g
gene id: 559295:KLTH0D16962g
uniprot id: C5DFQ1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A02200g
gene id: 559295:KLTH0A02200g
uniprot id: C5DBF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

559295:KLTH0H16148g
gene id: 559295:KLTH0H16148g
uniprot id: C5E3T4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

559295:KLTH0F02024g
gene id: 559295:KLTH0F02024g
uniprot id: C5DK60
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0C09922g
gene id: 559295:KLTH0C09922g
uniprot id: C5DEK1
names: Subunit
messages: Monomer.

559295:KLTH0H15246g
gene id: 559295:KLTH0H15246g
uniprot id: C5E3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0E08426g
gene id: 559295:KLTH0E08426g
uniprot id: C5DHZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

559295:KLTH0D14058g
gene id: 559295:KLTH0D14058g
uniprot id: C5DFC7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0D08426g
gene id: 559295:KLTH0D08426g
uniprot id: C5DGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization.
messages: cytoskeleton

559295:KLTH0G15642g
gene id: 559295:KLTH0G15642g
uniprot id: C5DNB5
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

559295:KLTH0G10604g
gene id: 559295:KLTH0G10604g
uniprot id: C5DMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

559295:KLTH0H03124g
gene id: 559295:KLTH0H03124g
uniprot id: C5E294
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

559295:KLTH0H07986g
gene id: 559295:KLTH0H07986g
uniprot id: C5E2V4
names: Similarity
messages: Belongs to the Rab GDI family.

559295:KLTH0H04972g
gene id: 559295:KLTH0H04972g
uniprot id: C5E2H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

559295:KLTH0E10648g
gene id: 559295:KLTH0E10648g
uniprot id: C5DI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

559295:KLTH0C02376g
gene id: 559295:KLTH0C02376g
uniprot id: C5DDN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

559295:KLTH0G15664g
gene id: 559295:KLTH0G15664g
uniprot id: C5DNB6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

559295:KLTH0D04400g
gene id: 559295:KLTH0D04400g
uniprot id: C5DGD4
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

559295:KLTH0F16302g
gene id: 559295:KLTH0F16302g
uniprot id: C5DJG7
names: Similarity
messages: Belongs to the peptidase M18 family.

559295:KLTH0H08932g
gene id: 559295:KLTH0H08932g
uniprot id: C5E2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

559295:KLTH0D15290g
gene id: 559295:KLTH0D15290g
uniprot id: C5DFI2
names: Similarity
messages: Belongs to the Mo25 family.

559295:KLTH0E08646g
gene id: 559295:KLTH0E08646g
uniprot id: C5DI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

559295:KLTH0D01056g
gene id: 559295:KLTH0D01056g
uniprot id: C5DFZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

559295:KLTH0G14432g
gene id: 559295:KLTH0G14432g
uniprot id: C5DN61
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

559295:KLTH0H14784g
gene id: 559295:KLTH0H14784g
uniprot id: C5E3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

559295:KLTH0H13794g
gene id: 559295:KLTH0H13794g
uniprot id: C5E3I3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

559295:KLTH0F13706g
gene id: 559295:KLTH0F13706g
uniprot id: C5DJ57
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

559295:KLTH0D09966g
gene id: 559295:KLTH0D09966g
uniprot id: C5DEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC29 family.
messages: Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Links the central plaque component SPC42 to the inner plaque component SPC110.
messages: Nucleus
messages: spindle pole body

559295:KLTH0B04928g
gene id: 559295:KLTH0B04928g
uniprot id: C5DCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

559295:KLTH0H02046g
gene id: 559295:KLTH0H02046g
uniprot id: C5E245
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

559295:KLTH0A03322g
gene id: 559295:KLTH0A03322g
uniprot id: C5DBK3
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E14168g
gene id: 559295:KLTH0E14168g
uniprot id: C5DIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

559295:KLTH0B03058g
gene id: 559295:KLTH0B03058g
uniprot id: C5DCH2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

559295:KLTH0H14168g
gene id: 559295:KLTH0H14168g
uniprot id: C5E3J8
names: Similarity
messages: Belongs to the OMP decarboxylase family.

559295:KLTH0B01892g
gene id: 559295:KLTH0B01892g
uniprot id: C5DCC4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

559295:KLTH0A01804g
gene id: 559295:KLTH0A01804g
uniprot id: C5DBD9
names: Similarity
messages: Belongs to the SCO1/2 family.

559295:KLTH0C00902g
gene id: 559295:KLTH0C00902g
uniprot id: C5DDG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

559295:KLTH0F17996g
gene id: 559295:KLTH0F17996g
uniprot id: C5DJP1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0A04158g
gene id: 559295:KLTH0A04158g
uniprot id: C5DBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

559295:KLTH0F04752g
gene id: 559295:KLTH0F04752g
uniprot id: C5DKH7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H11000g
gene id: 559295:KLTH0H11000g
uniprot id: C5E377
names: Similarity
messages: Belongs to the peptidase M20A family.

559295:KLTH0A05192g
gene id: 559295:KLTH0A05192g
uniprot id: C5DBT4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

559295:KLTH0D08668g
gene id: 559295:KLTH0D08668g
uniprot id: C5DGV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0B01694g
gene id: 559295:KLTH0B01694g
uniprot id: C5DCB5
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

559295:KLTH0G09834g
gene id: 559295:KLTH0G09834g
uniprot id: C5DML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: Cytoplasm

559295:KLTH0E05038g
gene id: 559295:KLTH0E05038g
uniprot id: C5DHK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

559295:KLTH0G13750g
gene id: 559295:KLTH0G13750g
uniprot id: C5DN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

559295:KLTH0B00132g
gene id: 559295:KLTH0B00132g
uniprot id: C5DC56
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E03542g
gene id: 559295:KLTH0E03542g
uniprot id: C5DHD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

559295:KLTH0H06006g
gene id: 559295:KLTH0H06006g
uniprot id: C5E2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

559295:KLTH0G03894g
gene id: 559295:KLTH0G03894g
uniprot id: C5DLV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

559295:KLTH0F15202g
gene id: 559295:KLTH0F15202g
uniprot id: C5DJC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VPS17 family.
messages: Component of the retromer complex.
messages: Plays a role in vesicular protein sorting.

559295:KLTH0G03344g
gene id: 559295:KLTH0G03344g
uniprot id: C5DLT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

559295:KLTH0A01122g
gene id: 559295:KLTH0A01122g
uniprot id: C5DBB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

559295:KLTH0D16940g
gene id: 559295:KLTH0D16940g
uniprot id: C5DFQ0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C02464g
gene id: 559295:KLTH0C02464g
uniprot id: C5DDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0E01540g
gene id: 559295:KLTH0E01540g
uniprot id: C5DH58
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F13464g
gene id: 559295:KLTH0F13464g
uniprot id: C5DJ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: actin patch

559295:KLTH0B09372g
gene id: 559295:KLTH0B09372g
uniprot id: C5DD95
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0A02134g
gene id: 559295:KLTH0A02134g
uniprot id: C5DBF3
names: Similarity
messages: Belongs to the LOC1 family.

559295:KLTH0E04752g
gene id: 559295:KLTH0E04752g
uniprot id: C5DHJ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

559295:KLTH0D07238g
gene id: 559295:KLTH0D07238g
uniprot id: C5DGQ6
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

559295:KLTH0C06622g
gene id: 559295:KLTH0C06622g
uniprot id: C5DE64
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

559295:KLTH0H08690g
gene id: 559295:KLTH0H08690g
uniprot id: C5E2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

559295:KLTH0G09350g
gene id: 559295:KLTH0G09350g
uniprot id: C5DMJ0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G18678g
gene id: 559295:KLTH0G18678g
uniprot id: C5DNP0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

559295:KLTH0H06754g
gene id: 559295:KLTH0H06754g
uniprot id: C5E2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GEP7 family.
messages: Involved in respiratory growth and required for cell survival in the absence of prohibitins.
messages: Mitochondrion membrane

559295:KLTH0B10428g
gene id: 559295:KLTH0B10428g
uniprot id: C5DDD6
names: Function
names: Similarity
messages: Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
messages: Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.

559295:KLTH0D02640g
gene id: 559295:KLTH0D02640g
uniprot id: C5DG60
names: Function
names: Similarity
messages: Belongs to the RRM RBM34 family.
messages: Involved in pre-25S rRNA processing.

559295:KLTH0G09922g
gene id: 559295:KLTH0G09922g
uniprot id: C5DML6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

559295:KLTH0E13244g
gene id: 559295:KLTH0E13244g
uniprot id: C5DIK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

559295:KLTH0D12254g
gene id: 559295:KLTH0D12254g
uniprot id: C5DF51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

559295:KLTH0D12122g
gene id: 559295:KLTH0D12122g
uniprot id: C5DF45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

559295:KLTH0E10956g
gene id: 559295:KLTH0E10956g
uniprot id: C5DIA4
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

559295:KLTH0G17292g
gene id: 559295:KLTH0G17292g
uniprot id: C5DNI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

559295:KLTH0H08228g
gene id: 559295:KLTH0H08228g
uniprot id: C5E2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

559295:KLTH0G16302g
gene id: 559295:KLTH0G16302g
uniprot id: C5DNE5
names: Similarity
messages: Belongs to the PPase family.

559295:KLTH0C07216g
gene id: 559295:KLTH0C07216g
uniprot id: C5DE90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

559295:KLTH0A00660g
gene id: 559295:KLTH0A00660g
uniprot id: C5DB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

559295:KLTH0D12232g
gene id: 559295:KLTH0D12232g
uniprot id: C5DF50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

559295:KLTH0F10384g
gene id: 559295:KLTH0F10384g
uniprot id: C5DL66
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

559295:KLTH0E07040g
gene id: 559295:KLTH0E07040g
uniprot id: C5DHT8
names: Similarity
messages: Belongs to the CWC26 family.

559295:KLTH0D10472g
gene id: 559295:KLTH0D10472g
uniprot id: C5DEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F17842g
gene id: 559295:KLTH0F17842g
uniprot id: C5DJN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

559295:KLTH0G04840g
gene id: 559295:KLTH0G04840g
uniprot id: C5DM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

559295:KLTH0D05522g
gene id: 559295:KLTH0D05522g
uniprot id: C5DGI2
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

559295:KLTH0D18128g
gene id: 559295:KLTH0D18128g
uniprot id: C5DFV0
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

559295:KLTH0F18282g
gene id: 559295:KLTH0F18282g
uniprot id: C5DJQ4
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

559295:KLTH0F18788g
gene id: 559295:KLTH0F18788g
uniprot id: C5DJS6
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

559295:KLTH0H12540g
gene id: 559295:KLTH0H12540g
uniprot id: C5E3D7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

559295:KLTH0H14058g
gene id: 559295:KLTH0H14058g
uniprot id: C5E3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

559295:KLTH0G10560g
gene id: 559295:KLTH0G10560g
uniprot id: C5DMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Nucleus

559295:KLTH0G09218g
gene id: 559295:KLTH0G09218g
uniprot id: C5DMI5
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

559295:KLTH0H16192g
gene id: 559295:KLTH0H16192g
uniprot id: C5E3T6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H15862g
gene id: 559295:KLTH0H15862g
uniprot id: C5E3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

559295:KLTH0D17116g
gene id: 559295:KLTH0D17116g
uniprot id: C5DFQ7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

559295:KLTH0F15268g
gene id: 559295:KLTH0F15268g
uniprot id: C5DJC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

559295:KLTH0C08404g
gene id: 559295:KLTH0C08404g
uniprot id: C5DED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

559295:KLTH0F00374g
gene id: 559295:KLTH0F00374g
uniprot id: C5DJY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

559295:KLTH0H05214g
gene id: 559295:KLTH0H05214g
uniprot id: C5E2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

559295:KLTH0D12672g
gene id: 559295:KLTH0D12672g
uniprot id: C5DF69
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

559295:KLTH0B02442g
gene id: 559295:KLTH0B02442g
uniprot id: C5DCE7
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.

559295:KLTH0F18964g
gene id: 559295:KLTH0F18964g
uniprot id: C5DJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

559295:KLTH0C04972g
gene id: 559295:KLTH0C04972g
uniprot id: C5DDZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Vacuole membrane

559295:KLTH0G09152g
gene id: 559295:KLTH0G09152g
uniprot id: C5DMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

559295:KLTH0H12452g
gene id: 559295:KLTH0H12452g
uniprot id: C5E3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

559295:KLTH0B03300g
gene id: 559295:KLTH0B03300g
uniprot id: C5DCI3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F13354g
gene id: 559295:KLTH0F13354g
uniprot id: C5DJ43
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

559295:KLTH0F18128g
gene id: 559295:KLTH0F18128g
uniprot id: C5DJP7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C05346g
gene id: 559295:KLTH0C05346g
uniprot id: C5DE08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

559295:KLTH0E06314g
gene id: 559295:KLTH0E06314g
uniprot id: C5DHQ8
names: Similarity
messages: Belongs to the PPP phosphatase family.

559295:KLTH0G05808g
gene id: 559295:KLTH0G05808g
uniprot id: C5DM42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0D17182g
gene id: 559295:KLTH0D17182g
uniprot id: C5DFR0
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0A01826g
gene id: 559295:KLTH0A01826g
uniprot id: C5DBE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

559295:KLTH0E07722g
gene id: 559295:KLTH0E07722g
uniprot id: C5DHW7
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

559295:KLTH0E12980g
gene id: 559295:KLTH0E12980g
uniprot id: C5DIJ3
names: Similarity
messages: Belongs to the SEN54 family.

559295:KLTH0F04576g
gene id: 559295:KLTH0F04576g
uniprot id: C5DKG9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H10802g
gene id: 559295:KLTH0H10802g
uniprot id: C5E368
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Mitochondrion inner membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

559295:KLTH0E04818g
gene id: 559295:KLTH0E04818g
uniprot id: C5DHJ5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

559295:KLTH0B01870g
gene id: 559295:KLTH0B01870g
uniprot id: C5DCC3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

559295:KLTH0E15598g
gene id: 559295:KLTH0E15598g
uniprot id: C5DIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

559295:KLTH0G14322g
gene id: 559295:KLTH0G14322g
uniprot id: C5DN56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

559295:KLTH0B07194g
gene id: 559295:KLTH0B07194g
uniprot id: C5DD01
names: Similarity
messages: Belongs to the peptidase M67A family. CSN5 subfamily.

559295:KLTH0E05808g
gene id: 559295:KLTH0E05808g
uniprot id: C5DHN6
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

559295:KLTH0E05346g
gene id: 559295:KLTH0E05346g
uniprot id: C5DHL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

559295:KLTH0D16544g
gene id: 559295:KLTH0D16544g
uniprot id: C5DFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

559295:KLTH0G02024g
gene id: 559295:KLTH0G02024g
uniprot id: C5DLN1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

559295:KLTH0D07370g
gene id: 559295:KLTH0D07370g
uniprot id: C5DGR0
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

559295:KLTH0F18216g
gene id: 559295:KLTH0F18216g
uniprot id: C5DJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0H05588g
gene id: 559295:KLTH0H05588g
uniprot id: C5E2J9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

559295:KLTH0D17314g
gene id: 559295:KLTH0D17314g
uniprot id: C5DFR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

559295:KLTH0F06028g
gene id: 559295:KLTH0F06028g
uniprot id: C5DKN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

559295:KLTH0H15642g
gene id: 559295:KLTH0H15642g
uniprot id: C5E3R1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

559295:KLTH0C02288g
gene id: 559295:KLTH0C02288g
uniprot id: C5DDM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

559295:KLTH0B08272g
gene id: 559295:KLTH0B08272g
uniprot id: C5DD48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure
messages: Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

559295:KLTH0G00836g
gene id: 559295:KLTH0G00836g
uniprot id: C5DLH8
names: Similarity
messages: Belongs to the APC10 family.

559295:KLTH0H11242g
gene id: 559295:KLTH0H11242g
uniprot id: C5E387
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

559295:KLTH0H02992g
gene id: 559295:KLTH0H02992g
uniprot id: C5E288
names: Similarity
messages: Belongs to the Tango6 family.

559295:KLTH0B02970g
gene id: 559295:KLTH0B02970g
uniprot id: C5DCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

559295:KLTH0G12122g
gene id: 559295:KLTH0G12122g
uniprot id: C5DMW1
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

559295:KLTH0D08976g
gene id: 559295:KLTH0D08976g
uniprot id: C5DGX1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

559295:KLTH0F08052g
gene id: 559295:KLTH0F08052g
uniprot id: C5DKW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

559295:KLTH0E08558g
gene id: 559295:KLTH0E08558g
uniprot id: C5DI00
names: Similarity
messages: Belongs to the cullin family.

559295:KLTH0D15906g
gene id: 559295:KLTH0D15906g
uniprot id: C5DFK7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

559295:KLTH0G02112g
gene id: 559295:KLTH0G02112g
uniprot id: C5DLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

559295:KLTH0D11330g
gene id: 559295:KLTH0D11330g
uniprot id: C5DF09
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

559295:KLTH0F13112g
gene id: 559295:KLTH0F13112g
uniprot id: C5DJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

559295:KLTH0C11242g
gene id: 559295:KLTH0C11242g
uniprot id: C5DEQ5
names: Similarity
messages: Belongs to the UPF0507 family.

559295:KLTH0H09658g
gene id: 559295:KLTH0H09658g
uniprot id: C5E322
names: Similarity
messages: Belongs to the IML2 family.

559295:KLTH0B08206g
gene id: 559295:KLTH0B08206g
uniprot id: C5DD45
names: Similarity
messages: Belongs to the AIM6 family.

559295:KLTH0F02112g
gene id: 559295:KLTH0F02112g
uniprot id: C5DK64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

559295:KLTH0F16654g
gene id: 559295:KLTH0F16654g
uniprot id: C5DJI3
names: Subcellular Location Annotation
messages: Golgi apparatus

559295:KLTH0D09284g
gene id: 559295:KLTH0D09284g
uniprot id: C5DGY5
names: Similarity
messages: Belongs to the cytochrome b5 family.

559295:KLTH0A03212g
gene id: 559295:KLTH0A03212g
uniprot id: C5DBJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

559295:KLTH0A04312g
gene id: 559295:KLTH0A04312g
uniprot id: C5DBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

559295:KLTH0B00154g
gene id: 559295:KLTH0B00154g
uniprot id: C5DC57
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H13772g
gene id: 559295:KLTH0H13772g
uniprot id: C5E3I2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E07414g
gene id: 559295:KLTH0E07414g
uniprot id: C5DHV4
names: Similarity
messages: Belongs to the Fmt family.

559295:KLTH0H15928g
gene id: 559295:KLTH0H15928g
uniprot id: C5E3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIM1 family.
messages: Lipid droplet
messages: Mitochondrion

559295:KLTH0A05830g
gene id: 559295:KLTH0A05830g
uniprot id: C5DBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

559295:KLTH0C05456g
gene id: 559295:KLTH0C05456g
uniprot id: C5DE13
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

559295:KLTH0F07304g
gene id: 559295:KLTH0F07304g
uniprot id: C5DKT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0H15026g
gene id: 559295:KLTH0H15026g
uniprot id: C5E3N5
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

559295:KLTH0E10076g
gene id: 559295:KLTH0E10076g
uniprot id: C5DI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

559295:KLTH0G04268g
gene id: 559295:KLTH0G04268g
uniprot id: C5DLX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPI19 family.
messages: Component of the phosphatidylinositol N-acetylglucosaminyltransferase (GPI-GlcNAc transferase) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

559295:KLTH0F18920g
gene id: 559295:KLTH0F18920g
uniprot id: C5DJT2
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

559295:KLTH0A05940g
gene id: 559295:KLTH0A05940g
uniprot id: C5DBW8
names: Similarity
messages: Belongs to the uridine kinase family.

559295:KLTH0C08206g
gene id: 559295:KLTH0C08206g
uniprot id: C5DED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

559295:KLTH0F14102g
gene id: 559295:KLTH0F14102g
uniprot id: C5DJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0F04664g
gene id: 559295:KLTH0F04664g
uniprot id: C5DKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G11352g
gene id: 559295:KLTH0G11352g
uniprot id: C5DMS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is required for recruitment of the basal transcription machinery. SLIK is proposed to have partly overlapping functions with SAGA.
messages: Nucleus

559295:KLTH0E13178g
gene id: 559295:KLTH0E13178g
uniprot id: C5DIK2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

559295:KLTH0G14498g
gene id: 559295:KLTH0G14498g
uniprot id: C5DN64
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0B02464g
gene id: 559295:KLTH0B02464g
uniprot id: C5DCE8
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

559295:KLTH0G12584g
gene id: 559295:KLTH0G12584g
uniprot id: C5DMY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

559295:KLTH0F12914g
gene id: 559295:KLTH0F12914g
uniprot id: C5DJ25
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E00154g
gene id: 559295:KLTH0E00154g
uniprot id: C5DGZ8
names: Similarity
messages: Belongs to the IUNH family.

559295:KLTH0A05104g
gene id: 559295:KLTH0A05104g
uniprot id: C5DBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0C10714g
gene id: 559295:KLTH0C10714g
uniprot id: C5DEN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
messages: Nucleus

559295:KLTH0G04796g
gene id: 559295:KLTH0G04796g
uniprot id: C5DLZ8
names: Similarity
messages: Belongs to the guanylate kinase family.

559295:KLTH0F01254g
gene id: 559295:KLTH0F01254g
uniprot id: C5DK26
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B09416g
gene id: 559295:KLTH0B09416g
uniprot id: C5DD97
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

559295:KLTH0D03476g
gene id: 559295:KLTH0D03476g
uniprot id: C5DG96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

559295:KLTH0G10252g
gene id: 559295:KLTH0G10252g
uniprot id: C5DMN1
names: Similarity
messages: Belongs to the PIGH family.

559295:KLTH0B05720g
gene id: 559295:KLTH0B05720g
uniprot id: C5DCT7
names: Similarity
messages: Belongs to the CAP family.

559295:KLTH0F09812g
gene id: 559295:KLTH0F09812g
uniprot id: C5DL43
names: Similarity
messages: Belongs to the lipin family.

559295:KLTH0G09196g
gene id: 559295:KLTH0G09196g
uniprot id: C5DMI4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G02376g
gene id: 559295:KLTH0G02376g
uniprot id: C5DLP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

559295:KLTH0H02200g
gene id: 559295:KLTH0H02200g
uniprot id: C5E252
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

559295:KLTH0D06248g
gene id: 559295:KLTH0D06248g
uniprot id: C5DGL3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F05544g
gene id: 559295:KLTH0F05544g
uniprot id: C5DKK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

559295:KLTH0G10450g
gene id: 559295:KLTH0G10450g
uniprot id: C5DMP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

559295:KLTH0C04290g
gene id: 559295:KLTH0C04290g
uniprot id: C5DDW3
names: Subcellular Location Annotation
messages: nuclear pore complex

559295:KLTH0E06028g
gene id: 559295:KLTH0E06028g
uniprot id: C5DHP6
names: Function
names: Similarity
messages: Belongs to the IRC19 family.
messages: Involved in sporulation and maintenance of the mitochondrial DNA. Is probably involved in a pathway contributing to genomic integrity (By similarity).

559295:KLTH0G05170g
gene id: 559295:KLTH0G05170g
uniprot id: C5DM15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

559295:KLTH0H07832g
gene id: 559295:KLTH0H07832g
uniprot id: C5E2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

559295:KLTH0H09702g
gene id: 559295:KLTH0H09702g
uniprot id: C5E324
names: Similarity
messages: Belongs to the actin family.

559295:KLTH0H08162g
gene id: 559295:KLTH0H08162g
uniprot id: C5E2W1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0F13574g
gene id: 559295:KLTH0F13574g
uniprot id: C5DJ52
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

559295:KLTH0H11264g
gene id: 559295:KLTH0H11264g
uniprot id: C5E388
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

559295:KLTH0E01144g
gene id: 559295:KLTH0E01144g
uniprot id: C5DH40
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A02508g
gene id: 559295:KLTH0A02508g
uniprot id: C5DBG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

559295:KLTH0F15884g
gene id: 559295:KLTH0F15884g
uniprot id: C5DJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

559295:KLTH0E12804g
gene id: 559295:KLTH0E12804g
uniprot id: C5DII6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

559295:KLTH0H03630g
gene id: 559295:KLTH0H03630g
uniprot id: C5E2B6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

559295:KLTH0D03520g
gene id: 559295:KLTH0D03520g
uniprot id: C5DG98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

559295:KLTH0A06600g
gene id: 559295:KLTH0A06600g
uniprot id: C5DBZ5
names: Similarity
messages: Belongs to the pyridoxine kinase family.

559295:KLTH0F04466g
gene id: 559295:KLTH0F04466g
uniprot id: C5DKG4
names: Similarity
messages: Belongs to the PGA52 family.

559295:KLTH0A01386g
gene id: 559295:KLTH0A01386g
uniprot id: C5DBC4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F10164g
gene id: 559295:KLTH0F10164g
uniprot id: C5DL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM36 family.
messages: Mitochondrion membrane

559295:KLTH0D08492g
gene id: 559295:KLTH0D08492g
uniprot id: C5DGV0
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

559295:KLTH0G02618g
gene id: 559295:KLTH0G02618g
uniprot id: C5DLQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Nucleus

559295:KLTH0D16786g
gene id: 559295:KLTH0D16786g
uniprot id: C5DFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G12870g
gene id: 559295:KLTH0G12870g
uniprot id: C5DMZ3
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

559295:KLTH0C06490g
gene id: 559295:KLTH0C06490g
uniprot id: C5DE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: Vacuole membrane
messages: autophagosome membrane

559295:KLTH0F07414g
gene id: 559295:KLTH0F07414g
uniprot id: C5DKT7
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

559295:KLTH0E10582g
gene id: 559295:KLTH0E10582g
uniprot id: C5DI88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

559295:KLTH0G17380g
gene id: 559295:KLTH0G17380g
uniprot id: C5DNI7
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

559295:KLTH0D13332g
gene id: 559295:KLTH0D13332g
uniprot id: C5DF96
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

559295:KLTH0G14762g
gene id: 559295:KLTH0G14762g
uniprot id: C5DN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

559295:KLTH0G03630g
gene id: 559295:KLTH0G03630g
uniprot id: C5DLU5
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

559295:KLTH0H14300g
gene id: 559295:KLTH0H14300g
uniprot id: C5E3K4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F15664g
gene id: 559295:KLTH0F15664g
uniprot id: C5DJE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

559295:KLTH0E12870g
gene id: 559295:KLTH0E12870g
uniprot id: C5DII9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E14718g
gene id: 559295:KLTH0E14718g
uniprot id: C5DIS1
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

559295:KLTH0F18832g
gene id: 559295:KLTH0F18832g
uniprot id: C5DJS8
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

559295:KLTH0G01056g
gene id: 559295:KLTH0G01056g
uniprot id: C5DLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G16126g
gene id: 559295:KLTH0G16126g
uniprot id: C5DND7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0D03410g
gene id: 559295:KLTH0D03410g
uniprot id: C5DG93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0B03696g
gene id: 559295:KLTH0B03696g
uniprot id: C5DCK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

559295:KLTH0D00792g
gene id: 559295:KLTH0D00792g
uniprot id: C5DFX8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

559295:KLTH0A07502g
gene id: 559295:KLTH0A07502g
uniprot id: C5DC36
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0C06886g
gene id: 559295:KLTH0C06886g
uniprot id: C5DE75
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0A02376g
gene id: 559295:KLTH0A02376g
uniprot id: C5DBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

559295:KLTH0D01254g
gene id: 559295:KLTH0D01254g
uniprot id: C5DFZ9
names: Similarity
messages: Belongs to the cyclin family.

559295:KLTH0G03586g
gene id: 559295:KLTH0G03586g
uniprot id: C5DLU3
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F17886g
gene id: 559295:KLTH0F17886g
uniprot id: C5DJN6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F07942g
gene id: 559295:KLTH0F07942g
uniprot id: C5DKW0
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

559295:KLTH0A02640g
gene id: 559295:KLTH0A02640g
uniprot id: C5DBH3
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

559295:KLTH0H03894g
gene id: 559295:KLTH0H03894g
uniprot id: C5E2C8
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

559295:KLTH0G14366g
gene id: 559295:KLTH0G14366g
uniprot id: C5DN58
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0E15862g
gene id: 559295:KLTH0E15862g
uniprot id: C5DIX2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B06204g
gene id: 559295:KLTH0B06204g
uniprot id: C5DCV9
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0H05764g
gene id: 559295:KLTH0H05764g
uniprot id: C5E2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERT1/acuK family.
messages: Nucleus
messages: Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).

559295:KLTH0A04686g
gene id: 559295:KLTH0A04686g
uniprot id: C5DBR1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

559295:KLTH0G15862g
gene id: 559295:KLTH0G15862g
uniprot id: C5DNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

559295:KLTH0H16214g
gene id: 559295:KLTH0H16214g
uniprot id: C5E3T7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C03476g
gene id: 559295:KLTH0C03476g
uniprot id: C5DDS7
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

559295:KLTH0F18040g
gene id: 559295:KLTH0F18040g
uniprot id: C5DJP3
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

559295:KLTH0F08756g
gene id: 559295:KLTH0F08756g
uniprot id: C5DKZ6
names: Similarity
messages: Belongs to the phosducin family.

559295:KLTH0H01452g
gene id: 559295:KLTH0H01452g
uniprot id: C5E218
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

559295:KLTH0D13552g
gene id: 559295:KLTH0D13552g
uniprot id: C5DFA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

559295:KLTH0F00726g
gene id: 559295:KLTH0F00726g
uniprot id: C5DK02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.

559295:KLTH0G15906g
gene id: 559295:KLTH0G15906g
uniprot id: C5DNC7
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

559295:KLTH0A02596g
gene id: 559295:KLTH0A02596g
uniprot id: C5DBH1
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0G19690g
gene id: 559295:KLTH0G19690g
uniprot id: C5DNT5
names: Similarity
messages: Belongs to the MNN1/MNT family.

559295:KLTH0C02002g
gene id: 559295:KLTH0C02002g
uniprot id: C5DDL6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

559295:KLTH0F02420g
gene id: 559295:KLTH0F02420g
uniprot id: C5DK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0H00308g
gene id: 559295:KLTH0H00308g
uniprot id: C5E1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0G12606g
gene id: 559295:KLTH0G12606g
uniprot id: C5DMY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

559295:KLTH0F14190g
gene id: 559295:KLTH0F14190g
uniprot id: C5DJ79
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

559295:KLTH0G10472g
gene id: 559295:KLTH0G10472g
uniprot id: C5DMP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

559295:KLTH0A05434g
gene id: 559295:KLTH0A05434g
uniprot id: C5DBU5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

559295:KLTH0G16522g
gene id: 559295:KLTH0G16522g
uniprot id: C5DNF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0A07524g
gene id: 559295:KLTH0A07524g
uniprot id: C5DC37
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

559295:KLTH0H14102g
gene id: 559295:KLTH0H14102g
uniprot id: C5E3J6
names: Similarity
messages: Belongs to the TPP enzyme family.

559295:KLTH0G16808g
gene id: 559295:KLTH0G16808g
uniprot id: C5DNG5
names: Function
names: Similarity
messages: ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly.
messages: Belongs to the YFH7 family.

559295:KLTH0E10868g
gene id: 559295:KLTH0E10868g
uniprot id: C5DIA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CWC2 family.
messages: Nucleus

559295:KLTH0C02134g
gene id: 559295:KLTH0C02134g
uniprot id: C5DDM2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C08822g
gene id: 559295:KLTH0C08822g
uniprot id: C5DEF8
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

559295:KLTH0E12782g
gene id: 559295:KLTH0E12782g
uniprot id: C5DII5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0H05896g
gene id: 559295:KLTH0H05896g
uniprot id: C5E2L3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H15994g
gene id: 559295:KLTH0H15994g
uniprot id: C5E3S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability (By similarity).
messages: Nucleus membrane

559295:KLTH0A05962g
gene id: 559295:KLTH0A05962g
uniprot id: C5DBW9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F08404g
gene id: 559295:KLTH0F08404g
uniprot id: C5DKY0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

559295:KLTH0D15378g
gene id: 559295:KLTH0D15378g
uniprot id: C5DFI5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C03102g
gene id: 559295:KLTH0C03102g
uniprot id: C5DDR1
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

559295:KLTH0A04334g
gene id: 559295:KLTH0A04334g
uniprot id: C5DBP6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

559295:KLTH0B08360g
gene id: 559295:KLTH0B08360g
uniprot id: C5DD52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source.

559295:KLTH0E11704g
gene id: 559295:KLTH0E11704g
uniprot id: C5DID7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ODC antizyme family.
messages: Interacts with ODC and thereby sterically blocks ODC homodimerization.
messages: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.

559295:KLTH0B09658g
gene id: 559295:KLTH0B09658g
uniprot id: C5DDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

559295:KLTH0B04466g
gene id: 559295:KLTH0B04466g
uniprot id: C5DCN2
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0F12584g
gene id: 559295:KLTH0F12584g
uniprot id: C5DLF2
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

559295:KLTH0A06380g
gene id: 559295:KLTH0A06380g
uniprot id: C5DBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

559295:KLTH0F00638g
gene id: 559295:KLTH0F00638g
uniprot id: C5DJZ8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E10120g
gene id: 559295:KLTH0E10120g
uniprot id: C5DI68
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0E04378g
gene id: 559295:KLTH0E04378g
uniprot id: C5DHH5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F06424g
gene id: 559295:KLTH0F06424g
uniprot id: C5DKP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3.
messages: Nucleus

559295:KLTH0B08866g
gene id: 559295:KLTH0B08866g
uniprot id: C5DD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

559295:KLTH0G02816g
gene id: 559295:KLTH0G02816g
uniprot id: C5DLR3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G03762g
gene id: 559295:KLTH0G03762g
uniprot id: C5DLV1
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

559295:KLTH0E05500g
gene id: 559295:KLTH0E05500g
uniprot id: C5DHM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG8 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

559295:KLTH0C06314g
gene id: 559295:KLTH0C06314g
uniprot id: C5DE51
names: Function
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0D05544g
gene id: 559295:KLTH0D05544g
uniprot id: C5DGI3
names: Similarity
messages: Belongs to the peptidase M18 family.

559295:KLTH0C03168g
gene id: 559295:KLTH0C03168g
uniprot id: C5DDR4
names: Similarity
messages: Belongs to the threonine aldolase family.

559295:KLTH0G08030g
gene id: 559295:KLTH0G08030g
uniprot id: C5DMD8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

559295:KLTH0A04290g
gene id: 559295:KLTH0A04290g
uniprot id: C5DBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

559295:KLTH0H02024g
gene id: 559295:KLTH0H02024g
uniprot id: C5E244
names: Similarity
messages: Belongs to the biotin--protein ligase family.

559295:KLTH0E12342g
gene id: 559295:KLTH0E12342g
uniprot id: C5DIG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

559295:KLTH0C07524g
gene id: 559295:KLTH0C07524g
uniprot id: C5DEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

559295:KLTH0E01584g
gene id: 559295:KLTH0E01584g
uniprot id: C5DH60
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

559295:KLTH0G15928g
gene id: 559295:KLTH0G15928g
uniprot id: C5DNC8
names: Similarity
messages: Belongs to the SIN1 family.

559295:KLTH0C01188g
gene id: 559295:KLTH0C01188g
uniprot id: C5DDI2
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

559295:KLTH0F15158g
gene id: 559295:KLTH0F15158g
uniprot id: C5DJB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

559295:KLTH0D06182g
gene id: 559295:KLTH0D06182g
uniprot id: C5DGL0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B07612g
gene id: 559295:KLTH0B07612g
uniprot id: C5DD19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

559295:KLTH0A05148g
gene id: 559295:KLTH0A05148g
uniprot id: C5DBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

559295:KLTH0E02024g
gene id: 559295:KLTH0E02024g
uniprot id: C5DH79
names: Similarity
messages: Belongs to the peptidase C12 family.

559295:KLTH0G19800g
gene id: 559295:KLTH0G19800g
uniprot id: C5DNT8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

559295:KLTH0D02904g
gene id: 559295:KLTH0D02904g
uniprot id: C5DG72
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

559295:KLTH0B01188g
gene id: 559295:KLTH0B01188g
uniprot id: C5DC94
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

559295:KLTH0D15444g
gene id: 559295:KLTH0D15444g
uniprot id: C5DFI8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

559295:KLTH0E08360g
gene id: 559295:KLTH0E08360g
uniprot id: C5DHZ2
names: Similarity
messages: Belongs to the VPS8 family.

559295:KLTH0F03322g
gene id: 559295:KLTH0F03322g
uniprot id: C5DKB8
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

559295:KLTH0H00286g
gene id: 559295:KLTH0H00286g
uniprot id: C5E1W9
names: Similarity
messages: Belongs to the globin family.

559295:KLTH0F16214g
gene id: 559295:KLTH0F16214g
uniprot id: C5DJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0A06688g
gene id: 559295:KLTH0A06688g
uniprot id: C5DBZ9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

559295:KLTH0F19404g
gene id: 559295:KLTH0F19404g
uniprot id: C5DJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

559295:KLTH0G05280g
gene id: 559295:KLTH0G05280g
uniprot id: C5DM20
names: Similarity
messages: Belongs to the dpy-30 family.

559295:KLTH0H07546g
gene id: 559295:KLTH0H07546g
uniprot id: C5E2T4
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

559295:KLTH0A07018g
gene id: 559295:KLTH0A07018g
uniprot id: C5DC14
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

559295:KLTH0F15620g
gene id: 559295:KLTH0F15620g
uniprot id: C5DJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

559295:KLTH0C04312g
gene id: 559295:KLTH0C04312g
uniprot id: C5DDW4
names: Similarity
messages: Belongs to the PPase family.

559295:KLTH0B04092g
gene id: 559295:KLTH0B04092g
uniprot id: C5DCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

559295:KLTH0F11572g
gene id: 559295:KLTH0F11572g
uniprot id: C5DLB3
names: Similarity
messages: Belongs to the PP2C family.

559295:KLTH0E04092g
gene id: 559295:KLTH0E04092g
uniprot id: C5DHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

559295:KLTH0G03784g
gene id: 559295:KLTH0G03784g
uniprot id: C5DLV2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

559295:KLTH0B00902g
gene id: 559295:KLTH0B00902g
uniprot id: C5DC82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

559295:KLTH0A06182g
gene id: 559295:KLTH0A06182g
uniprot id: C5DBX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0D06754g
gene id: 559295:KLTH0D06754g
uniprot id: C5DGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

559295:KLTH0D06094g
gene id: 559295:KLTH0D06094g
uniprot id: C5DGK6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

559295:KLTH0C08844g
gene id: 559295:KLTH0C08844g
uniprot id: C5DEF9
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

559295:KLTH0D10846g
gene id: 559295:KLTH0D10846g
uniprot id: C5DEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

559295:KLTH0G17710g
gene id: 559295:KLTH0G17710g
uniprot id: C5DNK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F06380g
gene id: 559295:KLTH0F06380g
uniprot id: C5DKP4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H09548g
gene id: 559295:KLTH0H09548g
uniprot id: C5E317
names: Similarity
messages: Belongs to the TRL1 family.

559295:KLTH0H01166g
gene id: 559295:KLTH0H01166g
uniprot id: C5E205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

559295:KLTH0C06534g
gene id: 559295:KLTH0C06534g
uniprot id: C5DE61
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0F11924g
gene id: 559295:KLTH0F11924g
uniprot id: C5DLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

559295:KLTH0H06644g
gene id: 559295:KLTH0H06644g
uniprot id: C5E2P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.

559295:KLTH0F13750g
gene id: 559295:KLTH0F13750g
uniprot id: C5DJ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

559295:KLTH0C11594g
gene id: 559295:KLTH0C11594g
uniprot id: C5DES0
names: Similarity
messages: Belongs to the MYBBP1A family.

559295:KLTH0H05566g
gene id: 559295:KLTH0H05566g
uniprot id: C5E2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

559295:KLTH0C08646g
gene id: 559295:KLTH0C08646g
uniprot id: C5DEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: kinetochore

559295:KLTH0G01144g
gene id: 559295:KLTH0G01144g
uniprot id: C5DLJ2
names: Similarity
messages: Belongs to the SAPS family.

559295:KLTH0E01496g
gene id: 559295:KLTH0E01496g
uniprot id: C5DH56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

559295:KLTH0H14696g
gene id: 559295:KLTH0H14696g
uniprot id: C5E3M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

559295:KLTH0E08712g
gene id: 559295:KLTH0E08712g
uniprot id: C5DI07
names: Similarity
messages: Belongs to the cytidylyltransferase family.

559295:KLTH0G00660g
gene id: 559295:KLTH0G00660g
uniprot id: C5DLH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity). The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (PubMed:26101253). Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
messages: Divalent metal cation.
messages: Nucleus

559295:KLTH0B03762g
gene id: 559295:KLTH0B03762g
uniprot id: C5DCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F07832g
gene id: 559295:KLTH0F07832g
uniprot id: C5DKV5
names: Similarity
messages: Belongs to the AHA1 family.

559295:KLTH0H03542g
gene id: 559295:KLTH0H03542g
uniprot id: C5E2B2
names: Similarity
messages: Belongs to the peptidase S16 family.

559295:KLTH0E13222g
gene id: 559295:KLTH0E13222g
uniprot id: C5DIK4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C05698g
gene id: 559295:KLTH0C05698g
uniprot id: C5DE23
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

559295:KLTH0F10252g
gene id: 559295:KLTH0F10252g
uniprot id: C5DL60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

559295:KLTH0E03146g
gene id: 559295:KLTH0E03146g
uniprot id: C5DHC4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A01188g
gene id: 559295:KLTH0A01188g
uniprot id: C5DBB5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

559295:KLTH0D15642g
gene id: 559295:KLTH0D15642g
uniprot id: C5DFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

559295:KLTH0D01738g
gene id: 559295:KLTH0D01738g
uniprot id: C5DG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

559295:KLTH0G16500g
gene id: 559295:KLTH0G16500g
uniprot id: C5DNF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0D11110g
gene id: 559295:KLTH0D11110g
uniprot id: C5DEZ9
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

559295:KLTH0B03476g
gene id: 559295:KLTH0B03476g
uniprot id: C5DCJ1
names: Similarity
messages: Belongs to the SDO1/SBDS family.

559295:KLTH0A04180g
gene id: 559295:KLTH0A04180g
uniprot id: C5DBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

559295:KLTH0F16148g
gene id: 559295:KLTH0F16148g
uniprot id: C5DJG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

559295:KLTH0G16610g
gene id: 559295:KLTH0G16610g
uniprot id: C5DNF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

559295:KLTH0H06886g
gene id: 559295:KLTH0H06886g
uniprot id: C5E2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

559295:KLTH0E03234g
gene id: 559295:KLTH0E03234g
uniprot id: C5DHC7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D15972g
gene id: 559295:KLTH0D15972g
uniprot id: C5DFK9
names: Similarity
messages: Belongs to the TSR2 family.

559295:KLTH0D04092g
gene id: 559295:KLTH0D04092g
uniprot id: C5DGC1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

559295:KLTH0D02684g
gene id: 559295:KLTH0D02684g
uniprot id: C5DG62
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

559295:KLTH0E11154g
gene id: 559295:KLTH0E11154g
uniprot id: C5DIB3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

559295:KLTH0F19470g
gene id: 559295:KLTH0F19470g
uniprot id: C5DJV7
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

559295:KLTH0F09042g
gene id: 559295:KLTH0F09042g
uniprot id: C5DL09
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C05962g
gene id: 559295:KLTH0C05962g
uniprot id: C5DE35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

559295:KLTH0C06292g
gene id: 559295:KLTH0C06292g
uniprot id: C5DE50
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0E10670g
gene id: 559295:KLTH0E10670g
uniprot id: C5DI92
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

559295:KLTH0G02574g
gene id: 559295:KLTH0G02574g
uniprot id: C5DLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNO1 family.
messages: nucleolus

559295:KLTH0G02926g
gene id: 559295:KLTH0G02926g
uniprot id: C5DLR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

559295:KLTH0F05192g
gene id: 559295:KLTH0F05192g
uniprot id: C5DKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0A06710g
gene id: 559295:KLTH0A06710g
uniprot id: C5DC00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0D08250g
gene id: 559295:KLTH0D08250g
uniprot id: C5DGT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

559295:KLTH0D00418g
gene id: 559295:KLTH0D00418g
uniprot id: C5DFW2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

559295:KLTH0F11682g
gene id: 559295:KLTH0F11682g
uniprot id: C5DLB8
names: Subcellular Location Annotation
messages: Mitochondrion

559295:KLTH0H03806g
gene id: 559295:KLTH0H03806g
uniprot id: C5E2C4
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

559295:KLTH0B04422g
gene id: 559295:KLTH0B04422g
uniprot id: C5DCN0
names: Similarity
messages: Belongs to the SEN15 family.

559295:KLTH0H11088g
gene id: 559295:KLTH0H11088g
uniprot id: C5E381
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

559295:KLTH0E00132g
gene id: 559295:KLTH0E00132g
uniprot id: C5DB82
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C10120g
gene id: 559295:KLTH0C10120g
uniprot id: C5DEL0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B01276g
gene id: 559295:KLTH0B01276g
uniprot id: C5DC97
names: Similarity
messages: Belongs to the thioredoxin family.

559295:KLTH0F13728g
gene id: 559295:KLTH0F13728g
uniprot id: C5DJ58
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

559295:KLTH0B02794g
gene id: 559295:KLTH0B02794g
uniprot id: C5DCG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

559295:KLTH0F13904g
gene id: 559295:KLTH0F13904g
uniprot id: C5DJ66
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

559295:KLTH0D00440g
gene id: 559295:KLTH0D00440g
uniprot id: C5DFW3
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

559295:KLTH0F11506g
gene id: 559295:KLTH0F11506g
uniprot id: C5DLB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

559295:KLTH0G06974g
gene id: 559295:KLTH0G06974g
uniprot id: C5DM93
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

559295:KLTH0H01672g
gene id: 559295:KLTH0H01672g
uniprot id: C5E228
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H01408g
gene id: 559295:KLTH0H01408g
uniprot id: C5E216
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

559295:KLTH0F02156g
gene id: 559295:KLTH0F02156g
uniprot id: C5DK66
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C00396g
gene id: 559295:KLTH0C00396g
uniprot id: C5DDE6
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

559295:KLTH0C08690g
gene id: 559295:KLTH0C08690g
uniprot id: C5DEF2
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

559295:KLTH0G03872g
gene id: 559295:KLTH0G03872g
uniprot id: C5DLV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

559295:KLTH0G18590g
gene id: 559295:KLTH0G18590g
uniprot id: C5DNN6
names: Similarity
messages: Belongs to the oligoribonuclease family.

559295:KLTH0A05016g
gene id: 559295:KLTH0A05016g
uniprot id: C5DBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM9 family.
messages: Mitochondrion

559295:KLTH0H10934g
gene id: 559295:KLTH0H10934g
uniprot id: C5E374
names: Similarity
messages: Belongs to the PAF1 family.

559295:KLTH0D06534g
gene id: 559295:KLTH0D06534g
uniprot id: C5DGM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

559295:KLTH0D09174g
gene id: 559295:KLTH0D09174g
uniprot id: C5DGY0
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

559295:KLTH0F18172g
gene id: 559295:KLTH0F18172g
uniprot id: C5DJP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

559295:KLTH0C07502g
gene id: 559295:KLTH0C07502g
uniprot id: C5DEA1
names: Similarity
messages: Belongs to the arginase family.

559295:KLTH0F17424g
gene id: 559295:KLTH0F17424g
uniprot id: C5DJL5
names: Similarity
messages: Belongs to the UPF0538 family.

559295:KLTH0C09460g
gene id: 559295:KLTH0C09460g
uniprot id: C5DEI3
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

559295:KLTH0F16896g
gene id: 559295:KLTH0F16896g
uniprot id: C5DJJ4
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

559295:KLTH0B07392g
gene id: 559295:KLTH0B07392g
uniprot id: C5DD10
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D03234g
gene id: 559295:KLTH0D03234g
uniprot id: C5DG87
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

559295:KLTH0E10890g
gene id: 559295:KLTH0E10890g
uniprot id: C5DIA1
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0E01518g
gene id: 559295:KLTH0E01518g
uniprot id: C5DH57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

559295:KLTH0H05654g
gene id: 559295:KLTH0H05654g
uniprot id: C5E2K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

559295:KLTH0B06534g
gene id: 559295:KLTH0B06534g
uniprot id: C5DCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IBD2 family.
messages: spindle pole

559295:KLTH0F09922g
gene id: 559295:KLTH0F09922g
uniprot id: C5DL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

559295:KLTH0D05192g
gene id: 559295:KLTH0D05192g
uniprot id: C5DGG7
names: Similarity
messages: Belongs to the KTI12 family.

559295:KLTH0F07898g
gene id: 559295:KLTH0F07898g
uniprot id: C5DKV8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F04840g
gene id: 559295:KLTH0F04840g
uniprot id: C5DKI1
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F19184g
gene id: 559295:KLTH0F19184g
uniprot id: C5DJU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

559295:KLTH0E09130g
gene id: 559295:KLTH0E09130g
uniprot id: C5DI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

559295:KLTH0D06578g
gene id: 559295:KLTH0D06578g
uniprot id: C5DGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

559295:KLTH0D09152g
gene id: 559295:KLTH0D09152g
uniprot id: C5DGX9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

559295:KLTH0F06490g
gene id: 559295:KLTH0F06490g
uniprot id: C5DKP8
names: Similarity
messages: Belongs to the actin family.

559295:KLTH0G02684g
gene id: 559295:KLTH0G02684g
uniprot id: C5DLQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G07062g
gene id: 559295:KLTH0G07062g
uniprot id: C5DM97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

559295:KLTH0A02112g
gene id: 559295:KLTH0A02112g
uniprot id: C5DBF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

559295:KLTH0G11330g
gene id: 559295:KLTH0G11330g
uniprot id: C5DMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

559295:KLTH0G16258g
gene id: 559295:KLTH0G16258g
uniprot id: C5DMP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0F11396g
gene id: 559295:KLTH0F11396g
uniprot id: C5DLA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud (By similarity).

559295:KLTH0D04312g
gene id: 559295:KLTH0D04312g
uniprot id: C5DGD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: The heme is bound between the two transmembrane subunits.

559295:KLTH0E05566g
gene id: 559295:KLTH0E05566g
uniprot id: C5DHM5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D13156g
gene id: 559295:KLTH0D13156g
uniprot id: C5DF89
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0F04554g
gene id: 559295:KLTH0F04554g
uniprot id: C5DKG8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A04818g
gene id: 559295:KLTH0A04818g
uniprot id: C5DBR7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

559295:KLTH0G14982g
gene id: 559295:KLTH0G14982g
uniprot id: C5DN86
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

559295:KLTH0G03850g
gene id: 559295:KLTH0G03850g
uniprot id: C5DLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

559295:KLTH0D12914g
gene id: 559295:KLTH0D12914g
uniprot id: C5DF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

559295:KLTH0C06358g
gene id: 559295:KLTH0C06358g
uniprot id: C5DE53
names: Similarity
messages: Belongs to the WD repeat rae1 family.

559295:KLTH0E09020g
gene id: 559295:KLTH0E09020g
uniprot id: C5DI19
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

559295:KLTH0F03828g
gene id: 559295:KLTH0F03828g
uniprot id: C5DKD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SOP4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.
messages: Membrane

559295:KLTH0F10912g
gene id: 559295:KLTH0F10912g
uniprot id: C5DL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane

559295:KLTH0E09768g
gene id: 559295:KLTH0E09768g
uniprot id: C5DI52
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

559295:KLTH0G10208g
gene id: 559295:KLTH0G10208g
uniprot id: C5DMM9
names: Similarity
messages: Belongs to the FYV10 family.

559295:KLTH0D00550g
gene id: 559295:KLTH0D00550g
uniprot id: C5DFW7
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

559295:KLTH0G19426g
gene id: 559295:KLTH0G19426g
uniprot id: C5DNS4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E14828g
gene id: 559295:KLTH0E14828g
uniprot id: C5DIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

559295:KLTH0C05016g
gene id: 559295:KLTH0C05016g
uniprot id: C5DDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

559295:KLTH0H10626g
gene id: 559295:KLTH0H10626g
uniprot id: C5E360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane
messages: Vacuole membrane

559295:KLTH0G05962g
gene id: 559295:KLTH0G05962g
uniprot id: C5DM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G17622g
gene id: 559295:KLTH0G17622g
uniprot id: C5DNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

559295:KLTH0D17424g
gene id: 559295:KLTH0D17424g
uniprot id: C5DFS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Nucleus

559295:KLTH0B09812g
gene id: 559295:KLTH0B09812g
uniprot id: C5DDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

559295:KLTH0G06226g
gene id: 559295:KLTH0G06226g
uniprot id: C5DM60
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0B06006g
gene id: 559295:KLTH0B06006g
uniprot id: C5DCV0
names: Similarity
messages: Belongs to the arginase family.

559295:KLTH0B03102g
gene id: 559295:KLTH0B03102g
uniprot id: C5DCH4
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

559295:KLTH0E10494g
gene id: 559295:KLTH0E10494g
uniprot id: C5DI84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

559295:KLTH0B05698g
gene id: 559295:KLTH0B05698g
uniprot id: C5DCT6
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

559295:KLTH0H02728g
gene id: 559295:KLTH0H02728g
uniprot id: C5E276
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G08184g
gene id: 559295:KLTH0G08184g
uniprot id: C5DME5
names: Similarity
messages: Belongs to the PP2C family.

559295:KLTH0C06402g
gene id: 559295:KLTH0C06402g
uniprot id: C5DE55
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

559295:KLTH0E13354g
gene id: 559295:KLTH0E13354g
uniprot id: C5DIL0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0G16280g
gene id: 559295:KLTH0G16280g
uniprot id: C5DNE4
names: Similarity
messages: Belongs to the TrpF family.

559295:KLTH0C07194g
gene id: 559295:KLTH0C07194g
uniprot id: C5DE89
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

559295:KLTH0F13948g
gene id: 559295:KLTH0F13948g
uniprot id: C5DJ68
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

559295:KLTH0F09724g
gene id: 559295:KLTH0F09724g
uniprot id: C5DL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

559295:KLTH0E06754g
gene id: 559295:KLTH0E06754g
uniprot id: C5DHS5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

559295:KLTH0D03608g
gene id: 559295:KLTH0D03608g
uniprot id: C5DGA2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

559295:KLTH0A02464g
gene id: 559295:KLTH0A02464g
uniprot id: C5DBG7
names: Similarity
messages: Belongs to the RRP12 family.

559295:KLTH0H12056g
gene id: 559295:KLTH0H12056g
uniprot id: C5E3B8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

559295:KLTH0C10912g
gene id: 559295:KLTH0C10912g
uniprot id: C5DEP4
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

559295:KLTH0F08668g
gene id: 559295:KLTH0F08668g
uniprot id: C5DKZ2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

559295:KLTH0F02816g
gene id: 559295:KLTH0F02816g
uniprot id: C5DK95
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

559295:KLTH0F17050g
gene id: 559295:KLTH0F17050g
uniprot id: C5DJK0
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0E11220g
gene id: 559295:KLTH0E11220g
uniprot id: C5DIB6
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F04862g
gene id: 559295:KLTH0F04862g
uniprot id: C5DKI2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E13442g
gene id: 559295:KLTH0E13442g
uniprot id: C5DIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0H13662g
gene id: 559295:KLTH0H13662g
uniprot id: C5E3H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

559295:KLTH0D13222g
gene id: 559295:KLTH0D13222g
uniprot id: C5DF92
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

559295:KLTH0C03718g
gene id: 559295:KLTH0C03718g
uniprot id: C5DDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

559295:KLTH0H09394g
gene id: 559295:KLTH0H09394g
uniprot id: C5E310
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

559295:KLTH0F19558g
gene id: 559295:KLTH0F19558g
uniprot id: C5DJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

559295:KLTH0E04180g
gene id: 559295:KLTH0E04180g
uniprot id: C5DHG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F14212g
gene id: 559295:KLTH0F14212g
uniprot id: C5DJ80
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D14916g
gene id: 559295:KLTH0D14916g
uniprot id: C5DFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BLOC1S1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1).
messages: Endosome

559295:KLTH0F19096g
gene id: 559295:KLTH0F19096g
uniprot id: C5DJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

559295:KLTH0D07084g
gene id: 559295:KLTH0D07084g
uniprot id: C5DGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

559295:KLTH0F15400g
gene id: 559295:KLTH0F15400g
uniprot id: C5DJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0D03652g
gene id: 559295:KLTH0D03652g
uniprot id: C5DGA4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

559295:KLTH0G13112g
gene id: 559295:KLTH0G13112g
uniprot id: C5DN03
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

559295:KLTH0B04004g
gene id: 559295:KLTH0B04004g
uniprot id: C5DCL3
names: Similarity
messages: Belongs to the NDK family.

559295:KLTH0D08294g
gene id: 559295:KLTH0D08294g
uniprot id: C5DGU1
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

559295:KLTH0C07480g
gene id: 559295:KLTH0C07480g
uniprot id: C5DEA0
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0C03410g
gene id: 559295:KLTH0C03410g
uniprot id: C5DDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

559295:KLTH0H01980g
gene id: 559295:KLTH0H01980g
uniprot id: C5E242
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

559295:KLTH0E13640g
gene id: 559295:KLTH0E13640g
uniprot id: C5DIM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: perinuclear region

559295:KLTH0F17798g
gene id: 559295:KLTH0F17798g
uniprot id: C5DJN2
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

559295:KLTH0F13794g
gene id: 559295:KLTH0F13794g
uniprot id: C5DJ61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

559295:KLTH0E02398g
gene id: 559295:KLTH0E02398g
uniprot id: C5DH93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

559295:KLTH0H14146g
gene id: 559295:KLTH0H14146g
uniprot id: C5E3J7
names: Similarity
messages: Belongs to the small Tim family.

559295:KLTH0E03828g
gene id: 559295:KLTH0E03828g
uniprot id: C5DHF0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H15444g
gene id: 559295:KLTH0H15444g
uniprot id: C5E3Q2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H06556g
gene id: 559295:KLTH0H06556g
uniprot id: C5E2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.
messages: Membrane

559295:KLTH0H10406g
gene id: 559295:KLTH0H10406g
uniprot id: C5E350
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

559295:KLTH0E11726g
gene id: 559295:KLTH0E11726g
uniprot id: C5DID8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

559295:KLTH0G14564g
gene id: 559295:KLTH0G14564g
uniprot id: C5DN67
names: Similarity
messages: Belongs to the XPC family.

559295:KLTH0F06666g
gene id: 559295:KLTH0F06666g
uniprot id: C5DKQ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0G02882g
gene id: 559295:KLTH0G02882g
uniprot id: C5DLR6
names: Similarity
messages: Belongs to the cytochrome P450 family.

559295:KLTH0A01694g
gene id: 559295:KLTH0A01694g
uniprot id: C5DBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

559295:KLTH0D04862g
gene id: 559295:KLTH0D04862g
uniprot id: C5DGF3
names: Similarity
messages: Belongs to the MUB1/samB family.

559295:KLTH0G04202g
gene id: 559295:KLTH0G04202g
uniprot id: C5DLX1
names: Similarity
messages: Belongs to the TAF11 family.

559295:KLTH0E13706g
gene id: 559295:KLTH0E13706g
uniprot id: C5DIM6
names: Subcellular Location Annotation
messages: Peroxisome membrane

559295:KLTH0A03102g
gene id: 559295:KLTH0A03102g
uniprot id: C5DBJ3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

559295:KLTH0G15576g
gene id: 559295:KLTH0G15576g
uniprot id: C5DNB2
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

559295:KLTH0F08184g
gene id: 559295:KLTH0F08184g
uniprot id: C5DKX0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

559295:KLTH0F01408g
gene id: 559295:KLTH0F01408g
uniprot id: C5DK33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

559295:KLTH0B08822g
gene id: 559295:KLTH0B08822g
uniprot id: C5DD71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0H09922g
gene id: 559295:KLTH0H09922g
uniprot id: C5E333
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

559295:KLTH0C09240g
gene id: 559295:KLTH0C09240g
uniprot id: C5DEH3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D02728g
gene id: 559295:KLTH0D02728g
uniprot id: C5DG64
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

559295:KLTH0E02750g
gene id: 559295:KLTH0E02750g
uniprot id: C5DHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0D10736g
gene id: 559295:KLTH0D10736g
uniprot id: C5DEY4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

559295:KLTH0H06776g
gene id: 559295:KLTH0H06776g
uniprot id: C5E2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.

559295:KLTH0E03894g
gene id: 559295:KLTH0E03894g
uniprot id: C5DHF3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H06710g
gene id: 559295:KLTH0H06710g
uniprot id: C5E2P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

559295:KLTH0A06578g
gene id: 559295:KLTH0A06578g
uniprot id: C5DBZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

559295:KLTH0F17490g
gene id: 559295:KLTH0F17490g
uniprot id: C5DJL8
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0B02948g
gene id: 559295:KLTH0B02948g
uniprot id: C5DCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

559295:KLTH0C04532g
gene id: 559295:KLTH0C04532g
uniprot id: C5DDX4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G16434g
gene id: 559295:KLTH0G16434g
uniprot id: C5DNF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

559295:KLTH0D04598g
gene id: 559295:KLTH0D04598g
uniprot id: C5DGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE2 family.
messages: Cytoplasm
messages: Homodimer and homotetramer.
messages: Nucleus
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell (By similarity).

559295:KLTH0D09614g
gene id: 559295:KLTH0D09614g
uniprot id: C5DET5
names: Similarity
messages: Belongs to the peptidase C14B family.

559295:KLTH0E00176g
gene id: 559295:KLTH0E00176g
uniprot id: C5DGZ9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E10142g
gene id: 559295:KLTH0E10142g
uniprot id: C5DI69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

559295:KLTH0E12144g
gene id: 559295:KLTH0E12144g
uniprot id: C5DIF6
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

559295:KLTH0G12518g
gene id: 559295:KLTH0G12518g
uniprot id: C5DMX9
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

559295:KLTH0G11484g
gene id: 559295:KLTH0G11484g
uniprot id: C5DMT5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

559295:KLTH0G12188g
gene id: 559295:KLTH0G12188g
uniprot id: C5DMW4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

559295:KLTH0F09768g
gene id: 559295:KLTH0F09768g
uniprot id: C5DL41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homodimer.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

559295:KLTH0D12364g
gene id: 559295:KLTH0D12364g
uniprot id: C5DF55
names: Function
names: Similarity
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.

559295:KLTH0C03630g
gene id: 559295:KLTH0C03630g
uniprot id: C5DDT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

559295:KLTH0E02354g
gene id: 559295:KLTH0E02354g
uniprot id: C5DH91
names: Subcellular Location Annotation
messages: Vacuole

559295:KLTH0B04906g
gene id: 559295:KLTH0B04906g
uniprot id: C5DCQ1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

559295:KLTH0F09790g
gene id: 559295:KLTH0F09790g
uniprot id: C5DL42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0H10384g
gene id: 559295:KLTH0H10384g
uniprot id: C5E349
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome subunit S5B/HSM3 family.
messages: Cytoplasm
messages: Involved in DNA mismatch repair in slow-growing cells. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).

559295:KLTH0F17446g
gene id: 559295:KLTH0F17446g
uniprot id: C5DJL6
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

559295:KLTH0H03564g
gene id: 559295:KLTH0H03564g
uniprot id: C5E2B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

559295:KLTH0B00594g
gene id: 559295:KLTH0B00594g
uniprot id: C5DC75
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G19668g
gene id: 559295:KLTH0G19668g
uniprot id: C5DNT4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F14476g
gene id: 559295:KLTH0F14476g
uniprot id: C5DJ90
names: Similarity
messages: Belongs to the taffazin family.

559295:KLTH0G06248g
gene id: 559295:KLTH0G06248g
uniprot id: C5DM61
names: Similarity
messages: Belongs to the RNR ribonuclease family.

559295:KLTH0G00858g
gene id: 559295:KLTH0G00858g
uniprot id: C5DLH9
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

559295:KLTH0F12210g
gene id: 559295:KLTH0F12210g
uniprot id: C5DLD8
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

559295:KLTH0C04114g
gene id: 559295:KLTH0C04114g
uniprot id: C5DDV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0H12298g
gene id: 559295:KLTH0H12298g
uniprot id: C5E3C9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H05874g
gene id: 559295:KLTH0H05874g
uniprot id: C5E2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

559295:KLTH0H13992g
gene id: 559295:KLTH0H13992g
uniprot id: C5E3J1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0E13838g
gene id: 559295:KLTH0E13838g
uniprot id: C5DIN2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

559295:KLTH0G04400g
gene id: 559295:KLTH0G04400g
uniprot id: C5DLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

559295:KLTH0C07128g
gene id: 559295:KLTH0C07128g
uniprot id: C5DE86
names: Similarity
messages: Belongs to the PP2C family.

559295:KLTH0G14014g
gene id: 559295:KLTH0G14014g
uniprot id: C5DN43
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

559295:KLTH0C09152g
gene id: 559295:KLTH0C09152g
uniprot id: C5DEH1
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

559295:KLTH0D16610g
gene id: 559295:KLTH0D16610g
uniprot id: C5DFN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

559295:KLTH0F05170g
gene id: 559295:KLTH0F05170g
uniprot id: C5DKJ3
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

559295:KLTH0G04576g
gene id: 559295:KLTH0G04576g
uniprot id: C5DLY8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

559295:KLTH0G05896g
gene id: 559295:KLTH0G05896g
uniprot id: C5DM45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F07018g
gene id: 559295:KLTH0F07018g
uniprot id: C5DKS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

559295:KLTH0E06952g
gene id: 559295:KLTH0E06952g
uniprot id: C5DHT4
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F00308g
gene id: 559295:KLTH0F00308g
uniprot id: C5DJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
messages: Cytoplasm
messages: Homodimer.

559295:KLTH0H06248g
gene id: 559295:KLTH0H06248g
uniprot id: C5E2M8
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

559295:KLTH0H16104g
gene id: 559295:KLTH0H16104g
uniprot id: C5E3T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Nucleus matrix

559295:KLTH0H08778g
gene id: 559295:KLTH0H08778g
uniprot id: C5E2Y3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

559295:KLTH0G15158g
gene id: 559295:KLTH0G15158g
uniprot id: C5DN94
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

559295:KLTH0H02310g
gene id: 559295:KLTH0H02310g
uniprot id: C5E257
names: Similarity
messages: Belongs to the Rho GDI family.

559295:KLTH0D17226g
gene id: 559295:KLTH0D17226g
uniprot id: C5DFR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

559295:KLTH0C01980g
gene id: 559295:KLTH0C01980g
uniprot id: C5DDL5
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

559295:KLTH0E09878g
gene id: 559295:KLTH0E09878g
uniprot id: C5DI57
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0D06138g
gene id: 559295:KLTH0D06138g
uniprot id: C5DGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Endosome membrane

559295:KLTH0H03036g
gene id: 559295:KLTH0H03036g
uniprot id: C5E290
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

559295:KLTH0F10538g
gene id: 559295:KLTH0F10538g
uniprot id: C5DL71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

559295:KLTH0G02266g
gene id: 559295:KLTH0G02266g
uniprot id: C5DLN9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C07018g
gene id: 559295:KLTH0C07018g
uniprot id: C5DE81
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

559295:KLTH0F05434g
gene id: 559295:KLTH0F05434g
uniprot id: C5DKK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

559295:KLTH0H09240g
gene id: 559295:KLTH0H09240g
uniprot id: C5E303
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

559295:KLTH0C02354g
gene id: 559295:KLTH0C02354g
uniprot id: C5DDN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0G04070g
gene id: 559295:KLTH0G04070g
uniprot id: C5DLW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

559295:KLTH0F18062g
gene id: 559295:KLTH0F18062g
uniprot id: C5DJP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0C08888g
gene id: 559295:KLTH0C08888g
uniprot id: C5DEG1
names: Similarity
messages: Belongs to the SF3A3 family.

559295:KLTH0G17072g
gene id: 559295:KLTH0G17072g
uniprot id: C5DNH5
names: Similarity
messages: Belongs to the YIP1 family.

559295:KLTH0C00660g
gene id: 559295:KLTH0C00660g
uniprot id: C5DDF8
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

559295:KLTH0F08162g
gene id: 559295:KLTH0F08162g
uniprot id: C5DKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

559295:KLTH0F17556g
gene id: 559295:KLTH0F17556g
uniprot id: C5DJM1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

559295:KLTH0H16258g
gene id: 559295:KLTH0H16258g
uniprot id: C5E3T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

559295:KLTH0D14234g
gene id: 559295:KLTH0D14234g
uniprot id: C5DFD5
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0F07172g
gene id: 559295:KLTH0F07172g
uniprot id: C5DKS7
names: Similarity
messages: Belongs to the ketopantoate reductase family.

559295:KLTH0F19822g
gene id: 559295:KLTH0F19822g
uniprot id: C5DJX3
names: Similarity
messages: Belongs to the DCP1 family.

559295:KLTH0E00462g
gene id: 559295:KLTH0E00462g
uniprot id: C5DDC3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H02794g
gene id: 559295:KLTH0H02794g
uniprot id: C5E279
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

559295:KLTH0E11770g
gene id: 559295:KLTH0E11770g
uniprot id: C5DIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

559295:KLTH0A01166g
gene id: 559295:KLTH0A01166g
uniprot id: C5DBB4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D06028g
gene id: 559295:KLTH0D06028g
uniprot id: C5DGK3
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

559295:KLTH0G16544g
gene id: 559295:KLTH0G16544g
uniprot id: C5DNF5
names: Similarity
messages: Belongs to the RMD1/sif2 family.

559295:KLTH0G16038g
gene id: 559295:KLTH0G16038g
uniprot id: C5DND3
names: Similarity
messages: Belongs to the MNN1/MNT family.

559295:KLTH0B08228g
gene id: 559295:KLTH0B08228g
uniprot id: C5DD46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

559295:KLTH0E14388g
gene id: 559295:KLTH0E14388g
uniprot id: C5DIQ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

559295:KLTH0A01936g
gene id: 559295:KLTH0A01936g
uniprot id: C5DBE5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

559295:KLTH0B06072g
gene id: 559295:KLTH0B06072g
uniprot id: C5DCV3
names: Similarity
messages: Belongs to the peptidase M14 family.

559295:KLTH0B07700g
gene id: 559295:KLTH0B07700g
uniprot id: C5DD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTT106 family.
messages: Chromosome
messages: Nucleus

559295:KLTH0C03366g
gene id: 559295:KLTH0C03366g
uniprot id: C5DDS3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

559295:KLTH0G11000g
gene id: 559295:KLTH0G11000g
uniprot id: C5DMR3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

559295:KLTH0B10318g
gene id: 559295:KLTH0B10318g
uniprot id: C5DDD3
names: Function
names: Similarity
messages: Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
messages: Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.

559295:KLTH0F07458g
gene id: 559295:KLTH0F07458g
uniprot id: C5DKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

559295:KLTH0E09570g
gene id: 559295:KLTH0E09570g
uniprot id: C5DI43
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D00132g
gene id: 559295:KLTH0D00132g
uniprot id: C5DFV4
names: Function
names: Similarity
messages: Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
messages: Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.

559295:KLTH0B04136g
gene id: 559295:KLTH0B04136g
uniprot id: C5DCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

559295:KLTH0F17468g
gene id: 559295:KLTH0F17468g
uniprot id: C5DJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD7 family.
messages: Nucleus
messages: Required for the proper initiation of DNA replication. Required for mitochondrial morphology (By similarity).
messages: spindle pole

559295:KLTH0E07788g
gene id: 559295:KLTH0E07788g
uniprot id: C5DHX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

559295:KLTH0C05170g
gene id: 559295:KLTH0C05170g
uniprot id: C5DE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0D13794g
gene id: 559295:KLTH0D13794g
uniprot id: C5DFB7
names: Similarity
messages: Belongs to the FBPase class 1 family.

559295:KLTH0G10692g
gene id: 559295:KLTH0G10692g
uniprot id: C5DMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0D06270g
gene id: 559295:KLTH0D06270g
uniprot id: C5DGL4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

559295:KLTH0E08294g
gene id: 559295:KLTH0E08294g
uniprot id: C5DHZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

559295:KLTH0H00968g
gene id: 559295:KLTH0H00968g
uniprot id: C5E1Z9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0C09350g
gene id: 559295:KLTH0C09350g
uniprot id: C5DEH8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H04488g
gene id: 559295:KLTH0H04488g
uniprot id: C5E2F3
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

559295:KLTH0H04224g
gene id: 559295:KLTH0H04224g
uniprot id: C5E2E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

559295:KLTH0B03784g
gene id: 559295:KLTH0B03784g
uniprot id: C5DCK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

559295:KLTH0A01782g
gene id: 559295:KLTH0A01782g
uniprot id: C5DBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

559295:KLTH0E10736g
gene id: 559295:KLTH0E10736g
uniprot id: C5DI95
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

559295:KLTH0B06622g
gene id: 559295:KLTH0B06622g
uniprot id: C5DCX8
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

559295:KLTH0F15048g
gene id: 559295:KLTH0F15048g
uniprot id: C5DJB4
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

559295:KLTH0G11154g
gene id: 559295:KLTH0G11154g
uniprot id: C5DMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0D17600g
gene id: 559295:KLTH0D17600g
uniprot id: C5DFS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

559295:KLTH0D03124g
gene id: 559295:KLTH0D03124g
uniprot id: C5DG82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.
messages: Mitochondrion inner membrane

559295:KLTH0A06226g
gene id: 559295:KLTH0A06226g
uniprot id: C5DBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase.
messages: Mitochondrion inner membrane

559295:KLTH0G18942g
gene id: 559295:KLTH0G18942g
uniprot id: C5DNQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

559295:KLTH0H12342g
gene id: 559295:KLTH0H12342g
uniprot id: C5E3D1
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

559295:KLTH0D04642g
gene id: 559295:KLTH0D04642g
uniprot id: C5DGE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0H07612g
gene id: 559295:KLTH0H07612g
uniprot id: C5E2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

559295:KLTH0G17028g
gene id: 559295:KLTH0G17028g
uniprot id: C5DNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

559295:KLTH0B03278g
gene id: 559295:KLTH0B03278g
uniprot id: C5DCI2
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0B09482g
gene id: 559295:KLTH0B09482g
uniprot id: C5DDA0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G04246g
gene id: 559295:KLTH0G04246g
uniprot id: C5DLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

559295:KLTH0G02860g
gene id: 559295:KLTH0G02860g
uniprot id: C5DLR5
names: Similarity
messages: Belongs to the IUNH family.

559295:KLTH0G05016g
gene id: 559295:KLTH0G05016g
uniprot id: C5DM08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.

559295:KLTH0G05940g
gene id: 559295:KLTH0G05940g
uniprot id: C5DM47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

559295:KLTH0F01430g
gene id: 559295:KLTH0F01430g
uniprot id: C5DK34
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

559295:KLTH0C03674g
gene id: 559295:KLTH0C03674g
uniprot id: C5DDT6
names: Similarity
messages: Belongs to the RNR ribonuclease family.

559295:KLTH0G07502g
gene id: 559295:KLTH0G07502g
uniprot id: C5DMB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

559295:KLTH0D15422g
gene id: 559295:KLTH0D15422g
uniprot id: C5DFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

559295:KLTH0H07898g
gene id: 559295:KLTH0H07898g
uniprot id: C5E2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0D00572g
gene id: 559295:KLTH0D00572g
uniprot id: C5DFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0F06798g
gene id: 559295:KLTH0F06798g
uniprot id: C5DKR2
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

559295:KLTH0C04224g
gene id: 559295:KLTH0C04224g
uniprot id: C5DDW0
names: Similarity
messages: Belongs to the sorting nexin family.

559295:KLTH0B09218g
gene id: 559295:KLTH0B09218g
uniprot id: C5DD88
names: Similarity
messages: Belongs to the EFG1 family.

559295:KLTH0G11814g
gene id: 559295:KLTH0G11814g
uniprot id: C5DMV0
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

559295:KLTH0E15224g
gene id: 559295:KLTH0E15224g
uniprot id: C5DIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0H15312g
gene id: 559295:KLTH0H15312g
uniprot id: C5E3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

559295:KLTH0D08272g
gene id: 559295:KLTH0D08272g
uniprot id: C5DGU0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

559295:KLTH0H01892g
gene id: 559295:KLTH0H01892g
uniprot id: C5E238
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

559295:KLTH0A06864g
gene id: 559295:KLTH0A06864g
uniprot id: C5DC07
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

559295:KLTH0G06864g
gene id: 559295:KLTH0G06864g
uniprot id: C5DM88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

559295:KLTH0G10120g
gene id: 559295:KLTH0G10120g
uniprot id: C5DMM5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

559295:KLTH0D04422g
gene id: 559295:KLTH0D04422g
uniprot id: C5DGD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

559295:KLTH0F01606g
gene id: 559295:KLTH0F01606g
uniprot id: C5DK42
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G00946g
gene id: 559295:KLTH0G00946g
uniprot id: C5DLI3
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

559295:KLTH0D02552g
gene id: 559295:KLTH0D02552g
uniprot id: C5DG56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Mitochondrion
messages: Nucleus

559295:KLTH0C09482g
gene id: 559295:KLTH0C09482g
uniprot id: C5DEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity).
messages: Belongs to the complex I LYR family. MZM1 subfamily.
messages: Interacts with RIP1.
messages: Mitochondrion matrix

559295:KLTH0B08118g
gene id: 559295:KLTH0B08118g
uniprot id: C5DD42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

559295:KLTH0E15796g
gene id: 559295:KLTH0E15796g
uniprot id: C5DIW9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H14894g
gene id: 559295:KLTH0H14894g
uniprot id: C5E3M9
names: Similarity
messages: Belongs to the NOP10 family.

559295:KLTH0G15202g
gene id: 559295:KLTH0G15202g
uniprot id: C5DN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

559295:KLTH0E04686g
gene id: 559295:KLTH0E04686g
uniprot id: C5DHI9
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

559295:KLTH0A05038g
gene id: 559295:KLTH0A05038g
uniprot id: C5DBS7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

559295:KLTH0F01782g
gene id: 559295:KLTH0F01782g
uniprot id: C5DK50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

559295:KLTH0F02970g
gene id: 559295:KLTH0F02970g
uniprot id: C5DKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

559295:KLTH0H10956g
gene id: 559295:KLTH0H10956g
uniprot id: C5E375
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

559295:KLTH0G07546g
gene id: 559295:KLTH0G07546g
uniprot id: C5DMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

559295:KLTH0A03410g
gene id: 559295:KLTH0A03410g
uniprot id: C5DBK7
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F06006g
gene id: 559295:KLTH0F06006g
uniprot id: C5DKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

559295:KLTH0F09372g
gene id: 559295:KLTH0F09372g
uniprot id: C5DL23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

559295:KLTH0D09372g
gene id: 559295:KLTH0D09372g
uniprot id: C5DGY9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

559295:KLTH0D07986g
gene id: 559295:KLTH0D07986g
uniprot id: C5DGT0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0F18634g
gene id: 559295:KLTH0F18634g
uniprot id: C5DJS0
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

559295:KLTH0F03718g
gene id: 559295:KLTH0F03718g
uniprot id: C5DKD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

559295:KLTH0E05588g
gene id: 559295:KLTH0E05588g
uniprot id: C5DHM6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0D07414g
gene id: 559295:KLTH0D07414g
uniprot id: C5DGR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

559295:KLTH0E09196g
gene id: 559295:KLTH0E09196g
uniprot id: C5DI27
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

559295:KLTH0F17820g
gene id: 559295:KLTH0F17820g
uniprot id: C5DJN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD2 family.
messages: Nucleus
messages: kinetochore
messages: spindle

559295:KLTH0E04906g
gene id: 559295:KLTH0E04906g
uniprot id: C5DHJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
messages: Nucleus

559295:KLTH0H12430g
gene id: 559295:KLTH0H12430g
uniprot id: C5E3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

559295:KLTH0C09548g
gene id: 559295:KLTH0C09548g
uniprot id: C5DEI7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

559295:KLTH0A00792g
gene id: 559295:KLTH0A00792g
uniprot id: C5DB98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0E11990g
gene id: 559295:KLTH0E11990g
uniprot id: C5DIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.

559295:KLTH0E07502g
gene id: 559295:KLTH0E07502g
uniprot id: C5DHV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

559295:KLTH0A04576g
gene id: 559295:KLTH0A04576g
uniprot id: C5DBQ6
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

559295:KLTH0G05192g
gene id: 559295:KLTH0G05192g
uniprot id: C5DM16
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

559295:KLTH0G09614g
gene id: 559295:KLTH0G09614g
uniprot id: C5DMK2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0F11286g
gene id: 559295:KLTH0F11286g
uniprot id: C5DLA1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C00374g
gene id: 559295:KLTH0C00374g
uniprot id: C5DDE5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0E14652g
gene id: 559295:KLTH0E14652g
uniprot id: C5DIR8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

559295:KLTH0G09020g
gene id: 559295:KLTH0G09020g
uniprot id: C5DMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0F04158g
gene id: 559295:KLTH0F04158g
uniprot id: C5DKF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

559295:KLTH0D14520g
gene id: 559295:KLTH0D14520g
uniprot id: C5DFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0E02948g
gene id: 559295:KLTH0E02948g
uniprot id: C5DHB5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

559295:KLTH0E08184g
gene id: 559295:KLTH0E08184g
uniprot id: C5DHY6
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D15686g
gene id: 559295:KLTH0D15686g
uniprot id: C5DFJ8
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

559295:KLTH0H07810g
gene id: 559295:KLTH0H07810g
uniprot id: C5E2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

559295:KLTH0C02090g
gene id: 559295:KLTH0C02090g
uniprot id: C5DDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

559295:KLTH0C04708g
gene id: 559295:KLTH0C04708g
uniprot id: C5DDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM39 family.
messages: Mitochondrion membrane

559295:KLTH0E15620g
gene id: 559295:KLTH0E15620g
uniprot id: C5DIW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0E16786g
gene id: 559295:KLTH0E16786g
uniprot id: C5DJ12
names: Similarity
messages: Belongs to the GST superfamily.

559295:KLTH0F01100g
gene id: 559295:KLTH0F01100g
uniprot id: C5DK19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

559295:KLTH0G03036g
gene id: 559295:KLTH0G03036g
uniprot id: C5DLS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

559295:KLTH0H02750g
gene id: 559295:KLTH0H02750g
uniprot id: C5E277
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

559295:KLTH0E01122g
gene id: 559295:KLTH0E01122g
uniprot id: C5DH39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG32 family.
messages: Mitochondrion outer membrane
messages: Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation (By similarity).
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

559295:KLTH0B02486g
gene id: 559295:KLTH0B02486g
uniprot id: C5DCE9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0D01936g
gene id: 559295:KLTH0D01936g
uniprot id: C5DG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0D00264g
gene id: 559295:KLTH0D00264g
uniprot id: C5DFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

559295:KLTH0G15752g
gene id: 559295:KLTH0G15752g
uniprot id: C5DNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

559295:KLTH0H05368g
gene id: 559295:KLTH0H05368g
uniprot id: C5E2I9
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

559295:KLTH0H00660g
gene id: 559295:KLTH0H00660g
uniprot id: C5E1Y5
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

559295:KLTH0E01320g
gene id: 559295:KLTH0E01320g
uniprot id: C5DH48
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F06820g
gene id: 559295:KLTH0F06820g
uniprot id: C5DKR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

559295:KLTH0A07656g
gene id: 559295:KLTH0A07656g
uniprot id: C5DC43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

559295:KLTH0F06116g
gene id: 559295:KLTH0F06116g
uniprot id: C5DKN4
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

559295:KLTH0E15004g
gene id: 559295:KLTH0E15004g
uniprot id: C5DIT3
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0H14916g
gene id: 559295:KLTH0H14916g
uniprot id: C5E3N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

559295:KLTH0A00814g
gene id: 559295:KLTH0A00814g
uniprot id: C5DB99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

559295:KLTH0A02046g
gene id: 559295:KLTH0A02046g
uniprot id: C5DBE9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E04730g
gene id: 559295:KLTH0E04730g
uniprot id: C5DHJ1
names: Function
names: Similarity
messages: Belongs to the RRT5 family.
messages: May be involved in the modulation of rDNA transcription.

559295:KLTH0E05918g
gene id: 559295:KLTH0E05918g
uniprot id: C5DHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

559295:KLTH0D14036g
gene id: 559295:KLTH0D14036g
uniprot id: C5DFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

559295:KLTH0G06820g
gene id: 559295:KLTH0G06820g
uniprot id: C5DM86
names: Similarity
messages: Belongs to the RCAN family.

559295:KLTH0B09284g
gene id: 559295:KLTH0B09284g
uniprot id: C5DD91
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

559295:KLTH0G14630g
gene id: 559295:KLTH0G14630g
uniprot id: C5DN70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

559295:KLTH0C10142g
gene id: 559295:KLTH0C10142g
uniprot id: C5DEL1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G18612g
gene id: 559295:KLTH0G18612g
uniprot id: C5DNN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

559295:KLTH0F01914g
gene id: 559295:KLTH0F01914g
uniprot id: C5DK55
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

559295:KLTH0E01034g
gene id: 559295:KLTH0E01034g
uniprot id: C5DH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

559295:KLTH0E08536g
gene id: 559295:KLTH0E08536g
uniprot id: C5DHZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

559295:KLTH0H02486g
gene id: 559295:KLTH0H02486g
uniprot id: C5E265
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

559295:KLTH0E02970g
gene id: 559295:KLTH0E02970g
uniprot id: C5DHB6
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

559295:KLTH0C09284g
gene id: 559295:KLTH0C09284g
uniprot id: C5DEH5
names: Similarity
messages: Belongs to the AHA1 family.

559295:KLTH0D14696g
gene id: 559295:KLTH0D14696g
uniprot id: C5DFF6
names: Function
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.

559295:KLTH0F07876g
gene id: 559295:KLTH0F07876g
uniprot id: C5DKV7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

559295:KLTH0G09284g
gene id: 559295:KLTH0G09284g
uniprot id: C5DMI8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0H13926g
gene id: 559295:KLTH0H13926g
uniprot id: C5E3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

559295:KLTH0E14014g
gene id: 559295:KLTH0E14014g
uniprot id: C5DIP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

559295:KLTH0F00330g
gene id: 559295:KLTH0F00330g
uniprot id: C5DJY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0A06204g
gene id: 559295:KLTH0A06204g
uniprot id: C5DBX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

559295:KLTH0E16456g
gene id: 559295:KLTH0E16456g
uniprot id: C5DIZ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

559295:KLTH0D01496g
gene id: 559295:KLTH0D01496g
uniprot id: C5DG09
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

559295:KLTH0G10362g
gene id: 559295:KLTH0G10362g
uniprot id: C5DMN6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

559295:KLTH0H01716g
gene id: 559295:KLTH0H01716g
uniprot id: C5E230
names: Similarity
messages: Belongs to the SAS10 family.

559295:KLTH0D04928g
gene id: 559295:KLTH0D04928g
uniprot id: C5DGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0D12078g
gene id: 559295:KLTH0D12078g
uniprot id: C5DF43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

559295:KLTH0D09834g
gene id: 559295:KLTH0D09834g
uniprot id: C5DEU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

559295:KLTH0C00330g
gene id: 559295:KLTH0C00330g
uniprot id: C5DDE3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B03938g
gene id: 559295:KLTH0B03938g
uniprot id: C5DCL1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

559295:KLTH0E13068g
gene id: 559295:KLTH0E13068g
uniprot id: C5DIJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

559295:KLTH0A05786g
gene id: 559295:KLTH0A05786g
uniprot id: C5DBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

559295:KLTH0B04752g
gene id: 559295:KLTH0B04752g
uniprot id: C5DCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

559295:KLTH0D13838g
gene id: 559295:KLTH0D13838g
uniprot id: C5DFB9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D14982g
gene id: 559295:KLTH0D14982g
uniprot id: C5DFG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

559295:KLTH0G02948g
gene id: 559295:KLTH0G02948g
uniprot id: C5DLR9
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

559295:KLTH0E02904g
gene id: 559295:KLTH0E02904g
uniprot id: C5DHB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

559295:KLTH0H11660g
gene id: 559295:KLTH0H11660g
uniprot id: C5E3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

559295:KLTH0B09768g
gene id: 559295:KLTH0B09768g
uniprot id: C5DDB2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

559295:KLTH0H12012g
gene id: 559295:KLTH0H12012g
uniprot id: C5E3B7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

559295:KLTH0G05346g
gene id: 559295:KLTH0G05346g
uniprot id: C5DM23
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

559295:KLTH0H05346g
gene id: 559295:KLTH0H05346g
uniprot id: C5E2I8
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

559295:KLTH0F08382g
gene id: 559295:KLTH0F08382g
uniprot id: C5DKX9
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0A05126g
gene id: 559295:KLTH0A05126g
uniprot id: C5DBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GET2 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

559295:KLTH0C08976g
gene id: 559295:KLTH0C08976g
uniprot id: C5DEG5
names: Similarity
messages: Belongs to the MNN1/MNT family.

559295:KLTH0H07722g
gene id: 559295:KLTH0H07722g
uniprot id: C5E2U2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

559295:KLTH0F02530g
gene id: 559295:KLTH0F02530g
uniprot id: C5DK83
names: Similarity
messages: Belongs to the UFD1 family.

559295:KLTH0H15378g
gene id: 559295:KLTH0H15378g
uniprot id: C5E3P9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

559295:KLTH0B09526g
gene id: 559295:KLTH0B09526g
uniprot id: C5DDA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

559295:KLTH0H12232g
gene id: 559295:KLTH0H12232g
uniprot id: C5E3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0H15004g
gene id: 559295:KLTH0H15004g
uniprot id: C5E3N4
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

559295:KLTH0H13090g
gene id: 559295:KLTH0H13090g
uniprot id: C5E3F9
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

559295:KLTH0C00528g
gene id: 559295:KLTH0C00528g
uniprot id: C5DDF2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

559295:KLTH0E07942g
gene id: 559295:KLTH0E07942g
uniprot id: C5DHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

559295:KLTH0H05478g
gene id: 559295:KLTH0H05478g
uniprot id: C5E2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0E01210g
gene id: 559295:KLTH0E01210g
uniprot id: C5DH43
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

559295:KLTH0E07084g
gene id: 559295:KLTH0E07084g
uniprot id: C5DHU0
names: Subcellular Location Annotation
messages: Nucleus membrane

559295:KLTH0G17556g
gene id: 559295:KLTH0G17556g
uniprot id: C5DNJ5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E11968g
gene id: 559295:KLTH0E11968g
uniprot id: C5DIE9
names: Similarity
messages: Belongs to the PGA52 family.

559295:KLTH0H07920g
gene id: 559295:KLTH0H07920g
uniprot id: C5E2V1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0F18370g
gene id: 559295:KLTH0F18370g
uniprot id: C5DJQ8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C04444g
gene id: 559295:KLTH0C04444g
uniprot id: C5DDX0
names: Similarity
messages: Belongs to the SAP30 family.

559295:KLTH0D01034g
gene id: 559295:KLTH0D01034g
uniprot id: C5DFY9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

559295:KLTH0D00880g
gene id: 559295:KLTH0D00880g
uniprot id: C5DFY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

559295:KLTH0E17138g
gene id: 559295:KLTH0E17138g
uniprot id: C5DJ18
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H04752g
gene id: 559295:KLTH0H04752g
uniprot id: C5E2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Membrane
messages: Mitochondrion

559295:KLTH0D00484g
gene id: 559295:KLTH0D00484g
uniprot id: C5DFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0B03740g
gene id: 559295:KLTH0B03740g
uniprot id: C5DCK2
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

559295:KLTH0B02046g
gene id: 559295:KLTH0B02046g
uniprot id: C5DCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0E05368g
gene id: 559295:KLTH0E05368g
uniprot id: C5DHL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
messages: Belongs to the GatF family.
messages: Mitochondrion inner membrane
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

559295:KLTH0F14498g
gene id: 559295:KLTH0F14498g
uniprot id: C5DJ91
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

559295:KLTH0F10868g
gene id: 559295:KLTH0F10868g
uniprot id: C5DL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

559295:KLTH0F13970g
gene id: 559295:KLTH0F13970g
uniprot id: C5DJ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

559295:KLTH0E09394g
gene id: 559295:KLTH0E09394g
uniprot id: C5DI35
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G01914g
gene id: 559295:KLTH0G01914g
uniprot id: C5DLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

559295:KLTH0C03344g
gene id: 559295:KLTH0C03344g
uniprot id: C5DDS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

559295:KLTH0E06292g
gene id: 559295:KLTH0E06292g
uniprot id: C5DHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

559295:KLTH0H10714g
gene id: 559295:KLTH0H10714g
uniprot id: C5E364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

559295:KLTH0B08096g
gene id: 559295:KLTH0B08096g
uniprot id: C5DD41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G04686g
gene id: 559295:KLTH0G04686g
uniprot id: C5DLZ3
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G03960g
gene id: 559295:KLTH0G03960g
uniprot id: C5DLW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

559295:KLTH0F03366g
gene id: 559295:KLTH0F03366g
uniprot id: C5DKC0
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

559295:KLTH0E08206g
gene id: 559295:KLTH0E08206g
uniprot id: C5DHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

559295:KLTH0C00506g
gene id: 559295:KLTH0C00506g
uniprot id: C5DDF1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0F19756g
gene id: 559295:KLTH0F19756g
uniprot id: C5DJX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

559295:KLTH0E13486g
gene id: 559295:KLTH0E13486g
uniprot id: C5DIL6
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

559295:KLTH0G12474g
gene id: 559295:KLTH0G12474g
uniprot id: C5DMX7
names: Function
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.

559295:KLTH0E11352g
gene id: 559295:KLTH0E11352g
uniprot id: C5DIC1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0D05434g
gene id: 559295:KLTH0D05434g
uniprot id: C5DGH8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D01716g
gene id: 559295:KLTH0D01716g
uniprot id: C5DG18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

559295:KLTH0H06798g
gene id: 559295:KLTH0H06798g
uniprot id: C5E2Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

559295:KLTH0F00924g
gene id: 559295:KLTH0F00924g
uniprot id: C5DK11
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: GTPase-activating protein for the ADP ribosylation factor family.

559295:KLTH0G12298g
gene id: 559295:KLTH0G12298g
uniprot id: C5DMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

559295:KLTH0D12386g
gene id: 559295:KLTH0D12386g
uniprot id: C5DF56
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

559295:KLTH0G11616g
gene id: 559295:KLTH0G11616g
uniprot id: C5DMU1
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

559295:KLTH0D12276g
gene id: 559295:KLTH0D12276g
uniprot id: C5DF52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

559295:KLTH0C04378g
gene id: 559295:KLTH0C04378g
uniprot id: C5DDW7
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E11792g
gene id: 559295:KLTH0E11792g
uniprot id: C5DIE1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C03388g
gene id: 559295:KLTH0C03388g
uniprot id: C5DDS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

559295:KLTH0G03300g
gene id: 559295:KLTH0G03300g
uniprot id: C5DLT4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

559295:KLTH0F12716g
gene id: 559295:KLTH0F12716g
uniprot id: C5DLF4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

559295:KLTH0G17138g
gene id: 559295:KLTH0G17138g
uniprot id: C5DNH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0B05258g
gene id: 559295:KLTH0B05258g
uniprot id: C5DCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

559295:KLTH0F19338g
gene id: 559295:KLTH0F19338g
uniprot id: C5DJV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat RTC1 family.
messages: May be involved in a process influencing telomere capping.
messages: Vacuole

559295:KLTH0D10626g
gene id: 559295:KLTH0D10626g
uniprot id: C5DEX9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D02794g
gene id: 559295:KLTH0D02794g
uniprot id: C5DG67
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

559295:KLTH0F16544g
gene id: 559295:KLTH0F16544g
uniprot id: C5DJH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

559295:KLTH0A00924g
gene id: 559295:KLTH0A00924g
uniprot id: C5DBA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

559295:KLTH0H04950g
gene id: 559295:KLTH0H04950g
uniprot id: C5E2H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.
messages: Nucleus

559295:KLTH0G05148g
gene id: 559295:KLTH0G05148g
uniprot id: C5DM14
names: Similarity
messages: Belongs to the cytochrome P450 family.

559295:KLTH0D15400g
gene id: 559295:KLTH0D15400g
uniprot id: C5DFI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

559295:KLTH0D08558g
gene id: 559295:KLTH0D08558g
uniprot id: C5DGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EIS1 family.
messages: Cell membrane
messages: Cytoplasmic granule
messages: Required for normal formation of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on plasma membrane and mark the site of endocytosis.

559295:KLTH0H02530g
gene id: 559295:KLTH0H02530g
uniprot id: C5E267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

559295:KLTH0F08976g
gene id: 559295:KLTH0F08976g
uniprot id: C5DL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

559295:KLTH0H13948g
gene id: 559295:KLTH0H13948g
uniprot id: C5E3I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

559295:KLTH0F03498g
gene id: 559295:KLTH0F03498g
uniprot id: C5DKC5
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0B05456g
gene id: 559295:KLTH0B05456g
uniprot id: C5DCS6
names: Similarity
messages: Belongs to the MIP18 family.

559295:KLTH0C07084g
gene id: 559295:KLTH0C07084g
uniprot id: C5DE84
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

559295:KLTH0H15510g
gene id: 559295:KLTH0H15510g
uniprot id: C5E3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

559295:KLTH0D16522g
gene id: 559295:KLTH0D16522g
uniprot id: C5DFN3
names: Similarity
messages: Belongs to the hexokinase family.

559295:KLTH0G17974g
gene id: 559295:KLTH0G17974g
uniprot id: C5DNL3
names: Subcellular Location Annotation
messages: nuclear pore complex

559295:KLTH0A06886g
gene id: 559295:KLTH0A06886g
uniprot id: C5DC08
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H05016g
gene id: 559295:KLTH0H05016g
uniprot id: C5E2H6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

559295:KLTH0G10670g
gene id: 559295:KLTH0G10670g
uniprot id: C5DMP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0B02156g
gene id: 559295:KLTH0B02156g
uniprot id: C5DCD4
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

559295:KLTH0E13046g
gene id: 559295:KLTH0E13046g
uniprot id: C5DIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.
messages: Membrane

559295:KLTH0D02310g
gene id: 559295:KLTH0D02310g
uniprot id: C5DG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0E03806g
gene id: 559295:KLTH0E03806g
uniprot id: C5DHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

559295:KLTH0C05500g
gene id: 559295:KLTH0C05500g
uniprot id: C5DE15
names: Similarity
messages: Belongs to the WD repeat mio family.

559295:KLTH0H15334g
gene id: 559295:KLTH0H15334g
uniprot id: C5E3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

559295:KLTH0H11902g
gene id: 559295:KLTH0H11902g
uniprot id: C5E3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

559295:KLTH0D12188g
gene id: 559295:KLTH0D12188g
uniprot id: C5DF48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

559295:KLTH0B04268g
gene id: 559295:KLTH0B04268g
uniprot id: C5DCM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

559295:KLTH0F07216g
gene id: 559295:KLTH0F07216g
uniprot id: C5DKS9
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

559295:KLTH0G04862g
gene id: 559295:KLTH0G04862g
uniprot id: C5DM01
names: Similarity
messages: Belongs to the RAD52 family.

559295:KLTH0C10890g
gene id: 559295:KLTH0C10890g
uniprot id: C5DEP3
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

559295:KLTH0H13750g
gene id: 559295:KLTH0H13750g
uniprot id: C5E3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWM2 family.
messages: nucleolus

559295:KLTH0F17182g
gene id: 559295:KLTH0F17182g
uniprot id: C5DJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

559295:KLTH0A03432g
gene id: 559295:KLTH0A03432g
uniprot id: C5DBK8
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

559295:KLTH0E06512g
gene id: 559295:KLTH0E06512g
uniprot id: C5DHR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0B09130g
gene id: 559295:KLTH0B09130g
uniprot id: C5DD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

559295:KLTH0D10032g
gene id: 559295:KLTH0D10032g
uniprot id: C5DEV3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

559295:KLTH0G07920g
gene id: 559295:KLTH0G07920g
uniprot id: C5DMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0G10340g
gene id: 559295:KLTH0G10340g
uniprot id: C5DMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

559295:KLTH0H08514g
gene id: 559295:KLTH0H08514g
uniprot id: C5E2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

559295:KLTH0H09130g
gene id: 559295:KLTH0H09130g
uniprot id: C5E2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

559295:KLTH0F06886g
gene id: 559295:KLTH0F06886g
uniprot id: C5DKR6
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

559295:KLTH0B04884g
gene id: 559295:KLTH0B04884g
uniprot id: C5DCQ0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

559295:KLTH0G02068g
gene id: 559295:KLTH0G02068g
uniprot id: C5DLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

559295:KLTH0E09900g
gene id: 559295:KLTH0E09900g
uniprot id: C5DI58
names: Similarity
messages: Belongs to the PhyH family.

559295:KLTH0F09262g
gene id: 559295:KLTH0F09262g
uniprot id: C5DL18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

559295:KLTH0D07018g
gene id: 559295:KLTH0D07018g
uniprot id: C5DGP6
names: Similarity
messages: Belongs to the PDCD5 family.

559295:KLTH0A07700g
gene id: 559295:KLTH0A07700g
uniprot id: C5DC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

559295:KLTH0D02838g
gene id: 559295:KLTH0D02838g
uniprot id: C5DG69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

559295:KLTH0D06644g
gene id: 559295:KLTH0D06644g
uniprot id: C5DGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0B05346g
gene id: 559295:KLTH0B05346g
uniprot id: C5DCS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

559295:KLTH0G04092g
gene id: 559295:KLTH0G04092g
uniprot id: C5DLW6
names: Similarity
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Homodimer.

559295:KLTH0H14190g
gene id: 559295:KLTH0H14190g
uniprot id: C5E3J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0D17798g
gene id: 559295:KLTH0D17798g
uniprot id: C5DFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0D11704g
gene id: 559295:KLTH0D11704g
uniprot id: C5DF26
names: Similarity
messages: Belongs to the TMA16 family.

559295:KLTH0F00242g
gene id: 559295:KLTH0F00242g
uniprot id: C5DJY2
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E01562g
gene id: 559295:KLTH0E01562g
uniprot id: C5DH59
names: Similarity
messages: Belongs to the yippee family.

559295:KLTH0F10648g
gene id: 559295:KLTH0F10648g
uniprot id: C5DL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM3 family.
messages: Membrane raft

559295:KLTH0G09086g
gene id: 559295:KLTH0G09086g
uniprot id: C5DMH9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G05918g
gene id: 559295:KLTH0G05918g
uniprot id: C5DM46
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

559295:KLTH0F01386g
gene id: 559295:KLTH0F01386g
uniprot id: C5DK32
names: Similarity
messages: Belongs to the RRP7 family.

559295:KLTH0G06710g
gene id: 559295:KLTH0G06710g
uniprot id: C5DM81
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

559295:KLTH0E15642g
gene id: 559295:KLTH0E15642g
uniprot id: C5DIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0E01188g
gene id: 559295:KLTH0E01188g
uniprot id: C5DH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

559295:KLTH0F07106g
gene id: 559295:KLTH0F07106g
uniprot id: C5DKS4
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

559295:KLTH0C08668g
gene id: 559295:KLTH0C08668g
uniprot id: C5DEF1
names: Similarity
messages: Belongs to the SF3A2 family.

559295:KLTH0B09504g
gene id: 559295:KLTH0B09504g
uniprot id: C5DDA1
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

559295:KLTH0E15378g
gene id: 559295:KLTH0E15378g
uniprot id: C5DIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

559295:KLTH0E14190g
gene id: 559295:KLTH0E14190g
uniprot id: C5DIP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

559295:KLTH0C11396g
gene id: 559295:KLTH0C11396g
uniprot id: C5DER2
names: Similarity
messages: Belongs to the peptidase S8 family.

559295:KLTH0D10406g
gene id: 559295:KLTH0D10406g
uniprot id: C5DEW9
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

559295:KLTH0F11066g
gene id: 559295:KLTH0F11066g
uniprot id: C5DL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

559295:KLTH0C01144g
gene id: 559295:KLTH0C01144g
uniprot id: C5DDI0
names: Similarity
messages: Belongs to the sulfiredoxin family.

559295:KLTH0F15730g
gene id: 559295:KLTH0F15730g
uniprot id: C5DJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F18304g
gene id: 559295:KLTH0F18304g
uniprot id: C5DJQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

559295:KLTH0B00836g
gene id: 559295:KLTH0B00836g
uniprot id: C5DC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

559295:KLTH0G15730g
gene id: 559295:KLTH0G15730g
uniprot id: C5DNB9
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

559295:KLTH0B06116g
gene id: 559295:KLTH0B06116g
uniprot id: C5DCV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0H03718g
gene id: 559295:KLTH0H03718g
uniprot id: C5E2C0
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0G13552g
gene id: 559295:KLTH0G13552g
uniprot id: C5DN23
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

559295:KLTH0E03586g
gene id: 559295:KLTH0E03586g
uniprot id: C5DHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

559295:KLTH0H14564g
gene id: 559295:KLTH0H14564g
uniprot id: C5E3L5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0E05456g
gene id: 559295:KLTH0E05456g
uniprot id: C5DHM0
names: Similarity
messages: Belongs to the TEL2 family.

559295:KLTH0G05830g
gene id: 559295:KLTH0G05830g
uniprot id: C5DM43
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

559295:KLTH0C01320g
gene id: 559295:KLTH0C01320g
uniprot id: C5DDI8
names: Similarity
messages: Belongs to the SURF6 family.

559295:KLTH0G18876g
gene id: 559295:KLTH0G18876g
uniprot id: C5DNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

559295:KLTH0D00858g
gene id: 559295:KLTH0D00858g
uniprot id: C5DFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

559295:KLTH0D03036g
gene id: 559295:KLTH0D03036g
uniprot id: C5DG78
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E14234g
gene id: 559295:KLTH0E14234g
uniprot id: C5DIQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

559295:KLTH0D14278g
gene id: 559295:KLTH0D14278g
uniprot id: C5DFD7
names: Similarity
messages: Belongs to the peptidase M16 family.

559295:KLTH0F07700g
gene id: 559295:KLTH0F07700g
uniprot id: C5DKU9
names: Similarity
messages: Belongs to the TMEM14 family.

559295:KLTH0D15818g
gene id: 559295:KLTH0D15818g
uniprot id: C5DFK3
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0B08888g
gene id: 559295:KLTH0B08888g
uniprot id: C5DD74
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

559295:KLTH0G04224g
gene id: 559295:KLTH0G04224g
uniprot id: C5DLX2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

559295:KLTH0H02618g
gene id: 559295:KLTH0H02618g
uniprot id: C5E271
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

559295:KLTH0G08404g
gene id: 559295:KLTH0G08404g
uniprot id: C5DMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0H07150g
gene id: 559295:KLTH0H07150g
uniprot id: C5E2R7
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

559295:KLTH0G04708g
gene id: 559295:KLTH0G04708g
uniprot id: C5DLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Membrane
messages: Vacuole membrane

559295:KLTH0H09966g
gene id: 559295:KLTH0H09966g
uniprot id: C5E335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

559295:KLTH0D16390g
gene id: 559295:KLTH0D16390g
uniprot id: C5DFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

559295:KLTH0E08668g
gene id: 559295:KLTH0E08668g
uniprot id: C5DI05
names: Similarity
messages: Belongs to the PRP18 family.

559295:KLTH0E15136g
gene id: 559295:KLTH0E15136g
uniprot id: C5DIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

559295:KLTH0C08426g
gene id: 559295:KLTH0C08426g
uniprot id: C5DEE0
names: Similarity
messages: Belongs to the RENT3 family.

559295:KLTH0C02508g
gene id: 559295:KLTH0C02508g
uniprot id: C5DDN8
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

559295:KLTH0G19536g
gene id: 559295:KLTH0G19536g
uniprot id: C5DNS8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

559295:KLTH0E05302g
gene id: 559295:KLTH0E05302g
uniprot id: C5DHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

559295:KLTH0C07678g
gene id: 559295:KLTH0C07678g
uniprot id: C5DEA8
names: Similarity
messages: Belongs to the VPS54 family.

559295:KLTH0F14278g
gene id: 559295:KLTH0F14278g
uniprot id: C5DJ83
names: Subcellular Location Annotation
messages: Nucleus membrane

559295:KLTH0F07150g
gene id: 559295:KLTH0F07150g
uniprot id: C5DKS6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

559295:KLTH0F07634g
gene id: 559295:KLTH0F07634g
uniprot id: C5DKU6
names: Similarity
messages: Belongs to the TIP41 family.

559295:KLTH0F01760g
gene id: 559295:KLTH0F01760g
uniprot id: C5DK49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

559295:KLTH0B08536g
gene id: 559295:KLTH0B08536g
uniprot id: C5DD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

559295:KLTH0G14894g
gene id: 559295:KLTH0G14894g
uniprot id: C5DN82
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

559295:KLTH0C10780g
gene id: 559295:KLTH0C10780g
uniprot id: C5DEN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

559295:KLTH0D06710g
gene id: 559295:KLTH0D06710g
uniprot id: C5DGN3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F06556g
gene id: 559295:KLTH0F06556g
uniprot id: C5DKQ1
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

559295:KLTH0G04950g
gene id: 559295:KLTH0G04950g
uniprot id: C5DM05
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

559295:KLTH0D10252g
gene id: 559295:KLTH0D10252g
uniprot id: C5DEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM41 family.
messages: Mitochondrion

559295:KLTH0E03784g
gene id: 559295:KLTH0E03784g
uniprot id: C5DHE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

559295:KLTH0G15950g
gene id: 559295:KLTH0G15950g
uniprot id: C5DNC9
names: Similarity
messages: Belongs to the peptidase S10 family.

559295:KLTH0G08492g
gene id: 559295:KLTH0G08492g
uniprot id: C5DMF6
names: Similarity
messages: Belongs to the END3 family.

559295:KLTH0H12936g
gene id: 559295:KLTH0H12936g
uniprot id: C5E3F2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

559295:KLTH0E12122g
gene id: 559295:KLTH0E12122g
uniprot id: C5DIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

559295:KLTH0A03982g
gene id: 559295:KLTH0A03982g
uniprot id: C5DBN0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

559295:KLTH0A03652g
gene id: 559295:KLTH0A03652g
uniprot id: C5DBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0E06468g
gene id: 559295:KLTH0E06468g
uniprot id: C5DHR3
names: Similarity
messages: Belongs to the MT-A70-like family.

559295:KLTH0G02992g
gene id: 559295:KLTH0G02992g
uniprot id: C5DLS1
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

559295:KLTH0A05874g
gene id: 559295:KLTH0A05874g
uniprot id: C5DBW5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

559295:KLTH0F08734g
gene id: 559295:KLTH0F08734g
uniprot id: C5DKZ5
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

559295:KLTH0E07348g
gene id: 559295:KLTH0E07348g
uniprot id: C5DHV1
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

559295:KLTH0F05368g
gene id: 559295:KLTH0F05368g
uniprot id: C5DKK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

559295:KLTH0A04840g
gene id: 559295:KLTH0A04840g
uniprot id: C5DBR8
names: Similarity
messages: Belongs to the YOS1 family.

559295:KLTH0E00418g
gene id: 559295:KLTH0E00418g
uniprot id: C5DH09
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

559295:KLTH0G08426g
gene id: 559295:KLTH0G08426g
uniprot id: C5DMF4
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

559295:KLTH0B03234g
gene id: 559295:KLTH0B03234g
uniprot id: C5DCI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

559295:KLTH0D09922g
gene id: 559295:KLTH0D09922g
uniprot id: C5DEU8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

559295:KLTH0E14586g
gene id: 559295:KLTH0E14586g
uniprot id: C5DIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: spindle

559295:KLTH0C03916g
gene id: 559295:KLTH0C03916g
uniprot id: C5DDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

559295:KLTH0C02398g
gene id: 559295:KLTH0C02398g
uniprot id: C5DDN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

559295:KLTH0D14344g
gene id: 559295:KLTH0D14344g
uniprot id: C5DFE0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0G06644g
gene id: 559295:KLTH0G06644g
uniprot id: C5DM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm
messages: nucleolus

559295:KLTH0D10186g
gene id: 559295:KLTH0D10186g
uniprot id: C5DEV9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

559295:KLTH0G08690g
gene id: 559295:KLTH0G08690g
uniprot id: C5DMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

559295:KLTH0G19030g
gene id: 559295:KLTH0G19030g
uniprot id: C5DNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

559295:KLTH0F01804g
gene id: 559295:KLTH0F01804g
uniprot id: C5DK51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

559295:KLTH0H12078g
gene id: 559295:KLTH0H12078g
uniprot id: C5E3B9
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

559295:KLTH0E16390g
gene id: 559295:KLTH0E16390g
uniprot id: C5DIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

559295:KLTH0G14938g
gene id: 559295:KLTH0G14938g
uniprot id: C5DN84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

559295:KLTH0B02002g
gene id: 559295:KLTH0B02002g
uniprot id: C5DCC9
names: Similarity
messages: Belongs to the eIF-2-alpha family.

559295:KLTH0D14652g
gene id: 559295:KLTH0D14652g
uniprot id: C5DFF4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G03806g
gene id: 559295:KLTH0G03806g
uniprot id: C5DLV3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

559295:KLTH0H03608g
gene id: 559295:KLTH0H03608g
uniprot id: C5E2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

559295:KLTH0G15004g
gene id: 559295:KLTH0G15004g
uniprot id: C5DN87
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

559295:KLTH0F15906g
gene id: 559295:KLTH0F15906g
uniprot id: C5DJF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

559295:KLTH0H08250g
gene id: 559295:KLTH0H08250g
uniprot id: C5E2W5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

559295:KLTH0G06622g
gene id: 559295:KLTH0G06622g
uniprot id: C5DM77
names: Similarity
messages: Belongs to the RMD1/sif2 family.

559295:KLTH0A00308g
gene id: 559295:KLTH0A00308g
uniprot id: C5DB79
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D01760g
gene id: 559295:KLTH0D01760g
uniprot id: C5DG20
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0G17666g
gene id: 559295:KLTH0G17666g
uniprot id: C5DNK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

559295:KLTH0D04906g
gene id: 559295:KLTH0D04906g
uniprot id: C5DGF5
names: Similarity
messages: Belongs to the UPP synthase family.

559295:KLTH0F00836g
gene id: 559295:KLTH0F00836g
uniprot id: C5DK07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE28 family.
messages: Nucleus membrane
messages: Required for kinetochore binding by a discrete subset of kMAPs and motors. Involved in kinetochore-microtubule binding and the spindle assembly checkpoint (By similarity).
messages: kinetochore
messages: spindle pole body

559295:KLTH0H12782g
gene id: 559295:KLTH0H12782g
uniprot id: C5E3E7
names: Similarity
messages: Belongs to the peptidase M28 family.

559295:KLTH0G13970g
gene id: 559295:KLTH0G13970g
uniprot id: C5DN41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

559295:KLTH0H00990g
gene id: 559295:KLTH0H00990g
uniprot id: C5E200
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

559295:KLTH0A01078g
gene id: 559295:KLTH0A01078g
uniprot id: C5DBB1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G09042g
gene id: 559295:KLTH0G09042g
uniprot id: C5DMH7
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

559295:KLTH0E02728g
gene id: 559295:KLTH0E02728g
uniprot id: C5DHA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

559295:KLTH0E16764g
gene id: 559295:KLTH0E16764g
uniprot id: C5DJ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

559295:KLTH0E08470g
gene id: 559295:KLTH0E08470g
uniprot id: C5DHZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

559295:KLTH0E14608g
gene id: 559295:KLTH0E14608g
uniprot id: C5DIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

559295:KLTH0F03872g
gene id: 559295:KLTH0F03872g
uniprot id: C5DFA2
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

559295:KLTH0F06842g
gene id: 559295:KLTH0F06842g
uniprot id: C5DKR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

559295:KLTH0E00880g
gene id: 559295:KLTH0E00880g
uniprot id: C5DH28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

559295:KLTH0H10164g
gene id: 559295:KLTH0H10164g
uniprot id: C5E340
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex.
messages: Nucleus

559295:KLTH0E05654g
gene id: 559295:KLTH0E05654g
uniprot id: C5DHM9
names: Similarity
messages: Belongs to the FGGY kinase family.

559295:KLTH0H03080g
gene id: 559295:KLTH0H03080g
uniprot id: C5E292
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0C11154g
gene id: 559295:KLTH0C11154g
uniprot id: C5DEQ2
names: Similarity
messages: Belongs to the pirin family.

559295:KLTH0G19206g
gene id: 559295:KLTH0G19206g
uniprot id: C5DNR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

559295:KLTH0H07260g
gene id: 559295:KLTH0H07260g
uniprot id: C5E2S2
names: Similarity
messages: Belongs to the MYG1 family.

559295:KLTH0H13046g
gene id: 559295:KLTH0H13046g
uniprot id: C5E3F7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

559295:KLTH0H05984g
gene id: 559295:KLTH0H05984g
uniprot id: C5E2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD3 family.
messages: Nucleus
messages: kinetochore
messages: spindle

559295:KLTH0F14674g
gene id: 559295:KLTH0F14674g
uniprot id: C5DJ97
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H06336g
gene id: 559295:KLTH0H06336g
uniprot id: C5E2N2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

559295:KLTH0C06050g
gene id: 559295:KLTH0C06050g
uniprot id: C5DE39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.
messages: telomere

559295:KLTH0A02948g
gene id: 559295:KLTH0A02948g
uniprot id: C5DBI7
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

559295:KLTH0B06292g
gene id: 559295:KLTH0B06292g
uniprot id: C5DCW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

559295:KLTH0B01122g
gene id: 559295:KLTH0B01122g
uniprot id: C5DC91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

559295:KLTH0A05478g
gene id: 559295:KLTH0A05478g
uniprot id: C5DBU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

559295:KLTH0H07876g
gene id: 559295:KLTH0H07876g
uniprot id: C5E2U9
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

559295:KLTH0D14674g
gene id: 559295:KLTH0D14674g
uniprot id: C5DFF5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B05126g
gene id: 559295:KLTH0B05126g
uniprot id: C5DCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

559295:KLTH0F17336g
gene id: 559295:KLTH0F17336g
uniprot id: C5DJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

559295:KLTH0F16104g
gene id: 559295:KLTH0F16104g
uniprot id: C5DJG0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

559295:KLTH0G14256g
gene id: 559295:KLTH0G14256g
uniprot id: C5DN53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

559295:KLTH0F03696g
gene id: 559295:KLTH0F03696g
uniprot id: C5DKD2
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

559295:KLTH0E11924g
gene id: 559295:KLTH0E11924g
uniprot id: C5DIE7
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0A02970g
gene id: 559295:KLTH0A02970g
uniprot id: C5DBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

559295:KLTH0G00528g
gene id: 559295:KLTH0G00528g
uniprot id: C5DLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

559295:KLTH0E13112g
gene id: 559295:KLTH0E13112g
uniprot id: C5DIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

559295:KLTH0A04642g
gene id: 559295:KLTH0A04642g
uniprot id: C5DBQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

559295:KLTH0H11044g
gene id: 559295:KLTH0H11044g
uniprot id: C5E379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

559295:KLTH0F00506g
gene id: 559295:KLTH0F00506g
uniprot id: C5DJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

559295:KLTH0A06072g
gene id: 559295:KLTH0A06072g
uniprot id: C5DBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F17358g
gene id: 559295:KLTH0F17358g
uniprot id: C5DJL3
names: Similarity
messages: Belongs to the SGT1 family.

559295:KLTH0D12606g
gene id: 559295:KLTH0D12606g
uniprot id: C5DF66
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

559295:KLTH0G13574g
gene id: 559295:KLTH0G13574g
uniprot id: C5DN24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

559295:KLTH0D10670g
gene id: 559295:KLTH0D10670g
uniprot id: C5DEY1
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0H08448g
gene id: 559295:KLTH0H08448g
uniprot id: C5E2X1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

559295:KLTH0H04312g
gene id: 559295:KLTH0H04312g
uniprot id: C5E2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPS2 family.
messages: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
messages: Nucleus membrane
messages: spindle pole body

559295:KLTH0G10076g
gene id: 559295:KLTH0G10076g
uniprot id: C5DMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

559295:KLTH0D10538g
gene id: 559295:KLTH0D10538g
uniprot id: C5DEX5
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

559295:KLTH0D17534g
gene id: 559295:KLTH0D17534g
uniprot id: C5DFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

559295:KLTH0A03300g
gene id: 559295:KLTH0A03300g
uniprot id: C5DBK2
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

559295:KLTH0G08250g
gene id: 559295:KLTH0G08250g
uniprot id: C5DME8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

559295:KLTH0A07678g
gene id: 559295:KLTH0A07678g
uniprot id: C5DC44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

559295:KLTH0E12672g
gene id: 559295:KLTH0E12672g
uniprot id: C5DII0
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

559295:KLTH0B05786g
gene id: 559295:KLTH0B05786g
uniprot id: C5DCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

559295:KLTH0G06380g
gene id: 559295:KLTH0G06380g
uniprot id: C5DM67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

559295:KLTH0G08470g
gene id: 559295:KLTH0G08470g
uniprot id: C5DMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

559295:KLTH0D11660g
gene id: 559295:KLTH0D11660g
uniprot id: C5DF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG29 family.
messages: Preautophagosomal structure

559295:KLTH0B00572g
gene id: 559295:KLTH0B00572g
uniprot id: C5DC74
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F06952g
gene id: 559295:KLTH0F06952g
uniprot id: C5DKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

559295:KLTH0C06556g
gene id: 559295:KLTH0C06556g
uniprot id: C5DE62
names: Similarity
messages: Belongs to the heat shock protein 70 family.

559295:KLTH0C04026g
gene id: 559295:KLTH0C04026g
uniprot id: C5DDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G13882g
gene id: 559295:KLTH0G13882g
uniprot id: C5DN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

559295:KLTH0A04752g
gene id: 559295:KLTH0A04752g
uniprot id: C5DBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA2 family.
messages: Cell projection
messages: Cytoplasm

559295:KLTH0G03168g
gene id: 559295:KLTH0G03168g
uniprot id: C5DLS9
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

559295:KLTH0D05412g
gene id: 559295:KLTH0D05412g
uniprot id: C5DGH7
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

559295:KLTH0E00726g
gene id: 559295:KLTH0E00726g
uniprot id: C5DH21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKG1 family.
messages: Bud membrane
messages: Cell membrane
messages: Plays a role in cell wall integrity. Affects the cell wall polymer composition in the growing region of the cell (By similarity).

559295:KLTH0H07194g
gene id: 559295:KLTH0H07194g
uniprot id: C5E2R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Required for vacuolar assembly and vacuolar traffic.
messages: Vacuole

559295:KLTH0H02178g
gene id: 559295:KLTH0H02178g
uniprot id: C5E251
names: Similarity
messages: Belongs to the UPP synthase family.

559295:KLTH0G16390g
gene id: 559295:KLTH0G16390g
uniprot id: C5DNE9
names: Similarity
messages: Belongs to the UPP synthase family.

559295:KLTH0B05830g
gene id: 559295:KLTH0B05830g
uniprot id: C5DCU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

559295:KLTH0D06006g
gene id: 559295:KLTH0D06006g
uniprot id: C5DGK2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

559295:KLTH0D08954g
gene id: 559295:KLTH0D08954g
uniprot id: C5DGX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

559295:KLTH0E07744g
gene id: 559295:KLTH0E07744g
uniprot id: C5DHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

559295:KLTH0D01892g
gene id: 559295:KLTH0D01892g
uniprot id: C5DG26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

559295:KLTH0H00528g
gene id: 559295:KLTH0H00528g
uniprot id: C5E1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

559295:KLTH0E07700g
gene id: 559295:KLTH0E07700g
uniprot id: C5DHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

559295:KLTH0F10824g
gene id: 559295:KLTH0F10824g
uniprot id: C5DL84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ART10 family.
messages: Cytoplasm
messages: May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.

559295:KLTH0H12606g
gene id: 559295:KLTH0H12606g
uniprot id: C5E3E0
names: Similarity
messages: Belongs to the citrate synthase family.

559295:KLTH0F04598g
gene id: 559295:KLTH0F04598g
uniprot id: C5DKH0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

559295:KLTH0B06336g
gene id: 559295:KLTH0B06336g
uniprot id: C5DCW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

559295:KLTH0F02046g
gene id: 559295:KLTH0F02046g
uniprot id: C5DK61
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

559295:KLTH0G09570g
gene id: 559295:KLTH0G09570g
uniprot id: C5DMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM5 family.
messages: Vacuole membrane

559295:KLTH0D02750g
gene id: 559295:KLTH0D02750g
uniprot id: C5DG65
names: Similarity
names: Subunit
messages: Belongs to the SIL1 family.
messages: Interacts with KAR2.

559295:KLTH0E00484g
gene id: 559295:KLTH0E00484g
uniprot id: C5DH12
names: Similarity
messages: Belongs to the oxoprolinase family.

559295:KLTH0G13618g
gene id: 559295:KLTH0G13618g
uniprot id: C5DN26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0G13530g
gene id: 559295:KLTH0G13530g
uniprot id: C5DN22
names: Similarity
messages: Belongs to the eIF2D family.

559295:KLTH0H03256g
gene id: 559295:KLTH0H03256g
uniprot id: C5E2A0
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

559295:KLTH0H00880g
gene id: 559295:KLTH0H00880g
uniprot id: C5E1Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

559295:KLTH0D04444g
gene id: 559295:KLTH0D04444g
uniprot id: C5DGD6
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

559295:KLTH0G02662g
gene id: 559295:KLTH0G02662g
uniprot id: C5DLQ6
names: Similarity
messages: Belongs to the AAA ATPase family.

559295:KLTH0E08162g
gene id: 559295:KLTH0E08162g
uniprot id: C5DHY5
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

559295:KLTH0H14652g
gene id: 559295:KLTH0H14652g
uniprot id: C5E3L9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

559295:KLTH0F08272g
gene id: 559295:KLTH0F08272g
uniprot id: C5DKX4
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

559295:KLTH0B05478g
gene id: 559295:KLTH0B05478g
uniprot id: C5DCS7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

559295:KLTH0F08624g
gene id: 559295:KLTH0F08624g
uniprot id: C5DKZ0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

559295:KLTH0G07986g
gene id: 559295:KLTH0G07986g
uniprot id: C5DMD6
names: Similarity
messages: Belongs to the MNN1/MNT family.

559295:KLTH0H10648g
gene id: 559295:KLTH0H10648g
uniprot id: C5E361
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0B00550g
gene id: 559295:KLTH0B00550g
uniprot id: C5DC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

559295:KLTH0C06864g
gene id: 559295:KLTH0C06864g
uniprot id: C5DE74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YEL1 family.
messages: Bud neck
messages: Bud tip
messages: Cell membrane
messages: Cytoplasm
messages: Guanine nucleotide exchange factor for ARF3 required for localization of ARF3 to the bud neck and tip and involved in actin patch polarization.

559295:KLTH0H02970g
gene id: 559295:KLTH0H02970g
uniprot id: C5E287
names: Similarity
messages: Belongs to the heat shock protein 90 family.

559295:KLTH0F13200g
gene id: 559295:KLTH0F13200g
uniprot id: C5DJ37
names: Similarity
messages: Belongs to the TFIIB family.

559295:KLTH0E16368g
gene id: 559295:KLTH0E16368g
uniprot id: C5DIZ4
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

559295:KLTH0E13376g
gene id: 559295:KLTH0E13376g
uniprot id: C5DIL1
names: Similarity
messages: Belongs to the MGR2 family.

559295:KLTH0E16082g
gene id: 559295:KLTH0E16082g
uniprot id: C5DIY2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

559295:KLTH0F11198g
gene id: 559295:KLTH0F11198g
uniprot id: C5DL97
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

559295:KLTH0G15400g
gene id: 559295:KLTH0G15400g
uniprot id: C5DNA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

559295:KLTH0D16126g
gene id: 559295:KLTH0D16126g
uniprot id: C5DFL6
names: Similarity
messages: Belongs to the type-1 OGG1 family.

559295:KLTH0D07832g
gene id: 559295:KLTH0D07832g
uniprot id: C5DGS3
names: Similarity
messages: Belongs to the cytochrome P450 family.

559295:KLTH0D13002g
gene id: 559295:KLTH0D13002g
uniprot id: C5DF83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0E16148g
gene id: 559295:KLTH0E16148g
uniprot id: C5DIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

559295:KLTH0F08602g
gene id: 559295:KLTH0F08602g
uniprot id: C5DKY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

559295:KLTH0G06490g
gene id: 559295:KLTH0G06490g
uniprot id: C5DM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

559295:KLTH0H08008g
gene id: 559295:KLTH0H08008g
uniprot id: C5E2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

559295:KLTH0D01188g
gene id: 559295:KLTH0D01188g
uniprot id: C5DFZ6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

559295:KLTH0B09592g
gene id: 559295:KLTH0B09592g
uniprot id: C5DDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

559295:KLTH0D09482g
gene id: 559295:KLTH0D09482g
uniprot id: C5DGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

559295:KLTH0F14014g
gene id: 559295:KLTH0F14014g
uniprot id: C5DJ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

559295:KLTH0E03674g
gene id: 559295:KLTH0E03674g
uniprot id: C5DHE3
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

559295:KLTH0F07326g
gene id: 559295:KLTH0F07326g
uniprot id: C5DKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0F19008g
gene id: 559295:KLTH0F19008g
uniprot id: C5DJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

559295:KLTH0E14806g
gene id: 559295:KLTH0E14806g
uniprot id: C5DIS5
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

559295:KLTH0G12892g
gene id: 559295:KLTH0G12892g
uniprot id: C5DMZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

559295:KLTH0G00990g
gene id: 559295:KLTH0G00990g
uniprot id: C5DLI5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

559295:KLTH0F00704g
gene id: 559295:KLTH0F00704g
uniprot id: C5DK01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

559295:KLTH0E00308g
gene id: 559295:KLTH0E00308g
uniprot id: C5DH05
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

559295:KLTH0E12848g
gene id: 559295:KLTH0E12848g
uniprot id: C5DII8
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

559295:KLTH0H10670g
gene id: 559295:KLTH0H10670g
uniprot id: C5E362
names: Similarity
messages: Belongs to the SDHAF4 family.

559295:KLTH0D04224g
gene id: 559295:KLTH0D04224g
uniprot id: C5DGC6
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

559295:KLTH0H08096g
gene id: 559295:KLTH0H08096g
uniprot id: C5E2V8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

559295:KLTH0F09482g
gene id: 559295:KLTH0F09482g
uniprot id: C5DL28
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

559295:KLTH0C10604g
gene id: 559295:KLTH0C10604g
uniprot id: C5DEN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0E15400g
gene id: 559295:KLTH0E15400g
uniprot id: C5DIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

559295:KLTH0E14630g
gene id: 559295:KLTH0E14630g
uniprot id: C5DIR7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B09680g
gene id: 559295:KLTH0B09680g
uniprot id: C5DDA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

559295:KLTH0H15950g
gene id: 559295:KLTH0H15950g
uniprot id: C5E3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIM1 family.
messages: Lipid droplet
messages: Mitochondrion

559295:KLTH0F03740g
gene id: 559295:KLTH0F03740g
uniprot id: C5DKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

559295:KLTH0F14542g
gene id: 559295:KLTH0F14542g
uniprot id: C5DJ93
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

559295:KLTH0F05720g
gene id: 559295:KLTH0F05720g
uniprot id: C5DKL6
names: Subunit
messages: Consists of at least two heavy chains and a number of intermediate and light chains.

559295:KLTH0H06534g
gene id: 559295:KLTH0H06534g
uniprot id: C5E2P0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C02024g
gene id: 559295:KLTH0C02024g
uniprot id: C5DDL7
names: Similarity
messages: Belongs to the exportin family.

559295:KLTH0B07128g
gene id: 559295:KLTH0B07128g
uniprot id: C5DCZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

559295:KLTH0H06094g
gene id: 559295:KLTH0H06094g
uniprot id: C5E2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

559295:KLTH0E02420g
gene id: 559295:KLTH0E02420g
uniprot id: C5DH94
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

559295:KLTH0B02706g
gene id: 559295:KLTH0B02706g
uniprot id: C5DCF8
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

559295:KLTH0F08228g
gene id: 559295:KLTH0F08228g
uniprot id: C5DKX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

559295:KLTH0G04730g
gene id: 559295:KLTH0G04730g
uniprot id: C5DLZ5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

559295:KLTH0H04774g
gene id: 559295:KLTH0H04774g
uniprot id: C5E2G5
names: Similarity
messages: Belongs to the MAD1 family.

559295:KLTH0G17160g
gene id: 559295:KLTH0G17160g
uniprot id: C5DNH9
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

559295:KLTH0A01320g
gene id: 559295:KLTH0A01320g
uniprot id: C5DBC1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

559295:KLTH0E01716g
gene id: 559295:KLTH0E01716g
uniprot id: C5DH65
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

559295:KLTH0G06600g
gene id: 559295:KLTH0G06600g
uniprot id: C5DM76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

559295:KLTH0B10054g
gene id: 559295:KLTH0B10054g
uniprot id: C5DDC3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D16060g
gene id: 559295:KLTH0D16060g
uniprot id: C5DFL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

559295:KLTH0E10714g
gene id: 559295:KLTH0E10714g
uniprot id: C5DI94
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

559295:KLTH0G01694g
gene id: 559295:KLTH0G01694g
uniprot id: C5DLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

559295:KLTH0E05698g
gene id: 559295:KLTH0E05698g
uniprot id: C5DHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

559295:KLTH0G03674g
gene id: 559295:KLTH0G03674g
uniprot id: C5DLU7
names: Similarity
messages: Belongs to the AFG1 ATPase family.

559295:KLTH0D06226g
gene id: 559295:KLTH0D06226g
uniprot id: C5DGL2
names: Function
names: Similarity
messages: Belongs to the BYE1 family.
messages: Negative regulator of transcription elongation.

559295:KLTH0C01100g
gene id: 559295:KLTH0C01100g
uniprot id: C5DDH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G09438g
gene id: 559295:KLTH0G09438g
uniprot id: C5DMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

559295:KLTH0H06446g
gene id: 559295:KLTH0H06446g
uniprot id: C5E2N6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

559295:KLTH0A06974g
gene id: 559295:KLTH0A06974g
uniprot id: C5DC12
names: Similarity
messages: Belongs to the PAT1 family.

559295:KLTH0F13002g
gene id: 559295:KLTH0F13002g
uniprot id: C5DJ29
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

559295:KLTH0C01672g
gene id: 559295:KLTH0C01672g
uniprot id: C5DDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

559295:KLTH0G10626g
gene id: 559295:KLTH0G10626g
uniprot id: C5DMP7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

559295:KLTH0E05170g
gene id: 559295:KLTH0E05170g
uniprot id: C5DHK9
names: Similarity
messages: Belongs to the cyclin family.

559295:KLTH0C05808g
gene id: 559295:KLTH0C05808g
uniprot id: C5DE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0H11748g
gene id: 559295:KLTH0H11748g
uniprot id: C5E3A7
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

559295:KLTH0B01166g
gene id: 559295:KLTH0B01166g
uniprot id: C5DC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0G00418g
gene id: 559295:KLTH0G00418g
uniprot id: C5DLF9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

559295:KLTH0B01078g
gene id: 559295:KLTH0B01078g
uniprot id: C5DC89
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

559295:KLTH0G14696g
gene id: 559295:KLTH0G14696g
uniprot id: C5DN73
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G11462g
gene id: 559295:KLTH0G11462g
uniprot id: C5DMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

559295:KLTH0H00374g
gene id: 559295:KLTH0H00374g
uniprot id: C5E1X3
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

559295:KLTH0G04004g
gene id: 559295:KLTH0G04004g
uniprot id: C5DLW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

559295:KLTH0G12430g
gene id: 559295:KLTH0G12430g
uniprot id: C5DMX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

559295:KLTH0G16170g
gene id: 559295:KLTH0G16170g
uniprot id: C5DND9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

559295:KLTH0C08030g
gene id: 559295:KLTH0C08030g
uniprot id: C5DEC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

559295:KLTH0B06754g
gene id: 559295:KLTH0B06754g
uniprot id: C5DCY2
names: Similarity
messages: Belongs to the FAH family.

559295:KLTH0D06930g
gene id: 559295:KLTH0D06930g
uniprot id: C5DGP3
names: Similarity
messages: Belongs to the cytochrome b5 family.

559295:KLTH0G06754g
gene id: 559295:KLTH0G06754g
uniprot id: C5DM83
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F19932g
gene id: 559295:KLTH0F19932g
uniprot id: C5DJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.
messages: Secreted

559295:KLTH0E14080g
gene id: 559295:KLTH0E14080g
uniprot id: C5DIP3
names: Similarity
messages: Belongs to the group II decarboxylase family.

559295:KLTH0D08074g
gene id: 559295:KLTH0D08074g
uniprot id: C5DGT4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

559295:KLTH0H05940g
gene id: 559295:KLTH0H05940g
uniprot id: C5E2L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSA1 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

559295:KLTH0F09680g
gene id: 559295:KLTH0F09680g
uniprot id: C5DL37
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0H03982g
gene id: 559295:KLTH0H03982g
uniprot id: C5E2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: kinetochore
messages: spindle

559295:KLTH0G10714g
gene id: 559295:KLTH0G10714g
uniprot id: C5DMQ1
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

559295:KLTH0A01540g
gene id: 559295:KLTH0A01540g
uniprot id: C5DBD0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

559295:KLTH0H01298g
gene id: 559295:KLTH0H01298g
uniprot id: C5E211
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

559295:KLTH0C08162g
gene id: 559295:KLTH0C08162g
uniprot id: C5DEC9
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

559295:KLTH0F18942g
gene id: 559295:KLTH0F18942g
uniprot id: C5DJT3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

559295:KLTH0E12716g
gene id: 559295:KLTH0E12716g
uniprot id: C5DII2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

559295:KLTH0G09526g
gene id: 559295:KLTH0G09526g
uniprot id: C5DMJ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

559295:KLTH0E15906g
gene id: 559295:KLTH0E15906g
uniprot id: C5DIX4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

559295:KLTH0F19580g
gene id: 559295:KLTH0F19580g
uniprot id: C5DJW2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

559295:KLTH0E15994g
gene id: 559295:KLTH0E15994g
uniprot id: C5DIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

559295:KLTH0B04994g
gene id: 559295:KLTH0B04994g
uniprot id: C5DCQ5
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

559295:KLTH0A02024g
gene id: 559295:KLTH0A02024g
uniprot id: C5DBE8
names: Similarity
messages: Belongs to the peptidase M24B family.

559295:KLTH0G17314g
gene id: 559295:KLTH0G17314g
uniprot id: C5DNI4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

559295:KLTH0H01210g
gene id: 559295:KLTH0H01210g
uniprot id: C5E207
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

559295:KLTH0E07634g
gene id: 559295:KLTH0E07634g
uniprot id: C5DHW3
names: Similarity
messages: Belongs to the R-transferase family.

559295:KLTH0F09064g
gene id: 559295:KLTH0F09064g
uniprot id: C5DL10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0G07766g
gene id: 559295:KLTH0G07766g
uniprot id: C5DMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

559295:KLTH0F01078g
gene id: 559295:KLTH0F01078g
uniprot id: C5DK18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR1 family.
messages: Membrane

559295:KLTH0F15554g
gene id: 559295:KLTH0F15554g
uniprot id: C5DJD5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

559295:KLTH0G11132g
gene id: 559295:KLTH0G11132g
uniprot id: C5DMR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

559295:KLTH0H06292g
gene id: 559295:KLTH0H06292g
uniprot id: C5E2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

559295:KLTH0D15708g
gene id: 559295:KLTH0D15708g
uniprot id: C5DFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Membrane

559295:KLTH0C03300g
gene id: 559295:KLTH0C03300g
uniprot id: C5DDS0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

559295:KLTH0F14982g
gene id: 559295:KLTH0F14982g
uniprot id: C5DJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

559295:KLTH0D06490g
gene id: 559295:KLTH0D06490g
uniprot id: C5DGM3
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H00770g
gene id: 559295:KLTH0H00770g
uniprot id: C5E1Z0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

559295:KLTH0H07348g
gene id: 559295:KLTH0H07348g
uniprot id: C5E2S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHU2 family.
messages: Nucleus
messages: Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase. Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).

559295:KLTH0D03806g
gene id: 559295:KLTH0D03806g
uniprot id: C5DGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

559295:KLTH0E02112g
gene id: 559295:KLTH0E02112g
uniprot id: C5DH83
names: Subcellular Location Annotation
messages: Peroxisome membrane

559295:KLTH0H04180g
gene id: 559295:KLTH0H04180g
uniprot id: C5E2E1
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F07986g
gene id: 559295:KLTH0F07986g
uniprot id: C5DKW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

559295:KLTH0D01012g
gene id: 559295:KLTH0D01012g
uniprot id: C5DFY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

559295:KLTH0E10538g
gene id: 559295:KLTH0E10538g
uniprot id: C5DI86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

559295:KLTH0D04246g
gene id: 559295:KLTH0D04246g
uniprot id: C5DGC7
names: Similarity
messages: Belongs to the syntaxin family.

559295:KLTH0C07326g
gene id: 559295:KLTH0C07326g
uniprot id: C5DE95
names: Similarity
messages: Belongs to the peptidase C19 family.

559295:KLTH0F14036g
gene id: 559295:KLTH0F14036g
uniprot id: C5DJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.

559295:KLTH0D13772g
gene id: 559295:KLTH0D13772g
uniprot id: C5DFB6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

559295:KLTH0D10296g
gene id: 559295:KLTH0D10296g
uniprot id: C5DEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

559295:KLTH0E02816g
gene id: 559295:KLTH0E02816g
uniprot id: C5DHB0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0B03168g
gene id: 559295:KLTH0B03168g
uniprot id: C5DCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

559295:KLTH0D16148g
gene id: 559295:KLTH0D16148g
uniprot id: C5DFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

559295:KLTH0F06600g
gene id: 559295:KLTH0F06600g
uniprot id: C5DKQ3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B09966g
gene id: 559295:KLTH0B09966g
uniprot id: C5DDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.

559295:KLTH0G06138g
gene id: 559295:KLTH0G06138g
uniprot id: C5DM56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

559295:KLTH0H12518g
gene id: 559295:KLTH0H12518g
uniprot id: C5E3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

559295:KLTH0E08998g
gene id: 559295:KLTH0E08998g
uniprot id: C5DI18
names: Similarity
messages: Belongs to the PurH family.

559295:KLTH0A03542g
gene id: 559295:KLTH0A03542g
uniprot id: C5DBL3
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F16742g
gene id: 559295:KLTH0F16742g
uniprot id: C5DJI7
names: Similarity
messages: Belongs to the syntaxin family.

559295:KLTH0H09570g
gene id: 559295:KLTH0H09570g
uniprot id: C5E318
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.

559295:KLTH0A02332g
gene id: 559295:KLTH0A02332g
uniprot id: C5DBG1
names: Similarity
messages: Belongs to the patched family.

559295:KLTH0F02288g
gene id: 559295:KLTH0F02288g
uniprot id: C5DK72
names: Similarity
messages: Belongs to the peptidase S8 family.

559295:KLTH0H03740g
gene id: 559295:KLTH0H03740g
uniprot id: C5E2C1
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G18964g
gene id: 559295:KLTH0G18964g
uniprot id: C5DNQ3
names: Similarity
messages: Belongs to the multicopper oxidase family.

559295:KLTH0G18854g
gene id: 559295:KLTH0G18854g
uniprot id: C5DNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0C06952g
gene id: 559295:KLTH0C06952g
uniprot id: C5DE78
names: Similarity
messages: Belongs to the RICTOR family.

559295:KLTH0D09064g
gene id: 559295:KLTH0D09064g
uniprot id: C5DGX5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

559295:KLTH0F16412g
gene id: 559295:KLTH0F16412g
uniprot id: C5DJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

559295:KLTH0E04202g
gene id: 559295:KLTH0E04202g
uniprot id: C5DHG7
names: Similarity
messages: Belongs to the RNase H family.

559295:KLTH0G00462g
gene id: 559295:KLTH0G00462g
uniprot id: C5DLG1
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

559295:KLTH0F05896g
gene id: 559295:KLTH0F05896g
uniprot id: C5DKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

559295:KLTH0E13090g
gene id: 559295:KLTH0E13090g
uniprot id: C5DIJ8
names: Similarity
messages: Belongs to the threonine aldolase family.

559295:KLTH0E16324g
gene id: 559295:KLTH0E16324g
uniprot id: C5DIZ2
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

559295:KLTH0F10450g
gene id: 559295:KLTH0F10450g
uniprot id: C5DL69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
messages: P-body
messages: nucleoplasm

559295:KLTH0C01452g
gene id: 559295:KLTH0C01452g
uniprot id: C5DDJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA11 family.
messages: Cytoplasm

559295:KLTH0G11374g
gene id: 559295:KLTH0G11374g
uniprot id: C5DMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

559295:KLTH0C05786g
gene id: 559295:KLTH0C05786g
uniprot id: C5DE27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

559295:KLTH0G17116g
gene id: 559295:KLTH0G17116g
uniprot id: C5DNH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

559295:KLTH0C04796g
gene id: 559295:KLTH0C04796g
uniprot id: C5DDY4
names: Similarity
messages: Belongs to the amidase family.

559295:KLTH0D00110g
gene id: 559295:KLTH0D00110g
uniprot id: C5DDD7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

559295:KLTH0C01958g
gene id: 559295:KLTH0C01958g
uniprot id: C5DDL4
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

559295:KLTH0G01540g
gene id: 559295:KLTH0G01540g
uniprot id: C5DLL0
names: Similarity
messages: Belongs to the BolA/IbaG family.

559295:KLTH0H00264g
gene id: 559295:KLTH0H00264g
uniprot id: C5E1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

559295:KLTH0G08052g
gene id: 559295:KLTH0G08052g
uniprot id: C5DMD9
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

559295:KLTH0H14344g
gene id: 559295:KLTH0H14344g
uniprot id: C5E3K6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

559295:KLTH0F16874g
gene id: 559295:KLTH0F16874g
uniprot id: C5DJJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

559295:KLTH0C10978g
gene id: 559295:KLTH0C10978g
uniprot id: C5DEP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

559295:KLTH0D00990g
gene id: 559295:KLTH0D00990g
uniprot id: C5DFY7
names: Similarity
messages: Belongs to the BolA/IbaG family.

559295:KLTH0E00616g
gene id: 559295:KLTH0E00616g
uniprot id: C5DH16
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0E11132g
gene id: 559295:KLTH0E11132g
uniprot id: C5DIB2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

559295:KLTH0C11308g
gene id: 559295:KLTH0C11308g
uniprot id: C5DEQ8
names: Similarity
messages: Belongs to the NPR2 family.

559295:KLTH0E09152g
gene id: 559295:KLTH0E09152g
uniprot id: C5DI25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

559295:KLTH0H15554g
gene id: 559295:KLTH0H15554g
uniprot id: C5E3Q7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0H12738g
gene id: 559295:KLTH0H12738g
uniprot id: C5E3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

559295:KLTH0G16940g
gene id: 559295:KLTH0G16940g
uniprot id: C5DNG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

559295:KLTH0B05236g
gene id: 559295:KLTH0B05236g
uniprot id: C5DCR6
names: Similarity
messages: Belongs to the peptidase S1C family.

559295:KLTH0H02398g
gene id: 559295:KLTH0H02398g
uniprot id: C5E261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

559295:KLTH0E08052g
gene id: 559295:KLTH0E08052g
uniprot id: C5DHY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0D02376g
gene id: 559295:KLTH0D02376g
uniprot id: C5DG48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

559295:KLTH0H02002g
gene id: 559295:KLTH0H02002g
uniprot id: C5E243
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

559295:KLTH0F17776g
gene id: 559295:KLTH0F17776g
uniprot id: C5DJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

559295:KLTH0C08382g
gene id: 559295:KLTH0C08382g
uniprot id: C5DED8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

559295:KLTH0H00330g
gene id: 559295:KLTH0H00330g
uniprot id: C5E1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Preautophagosomal structure membrane

559295:KLTH0E03718g
gene id: 559295:KLTH0E03718g
uniprot id: C5DHE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C1D family.
messages: Nucleus
messages: Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.

559295:KLTH0C09988g
gene id: 559295:KLTH0C09988g
uniprot id: C5DEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

559295:KLTH0C00770g
gene id: 559295:KLTH0C00770g
uniprot id: C5DDG3
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

559295:KLTH0F09570g
gene id: 559295:KLTH0F09570g
uniprot id: C5DL32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

559295:KLTH0A05500g
gene id: 559295:KLTH0A05500g
uniprot id: C5DBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Golgi apparatus membrane
messages: Membrane

559295:KLTH0D03982g
gene id: 559295:KLTH0D03982g
uniprot id: C5DGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane

559295:KLTH0G18018g
gene id: 559295:KLTH0G18018g
uniprot id: C5DNL4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

559295:KLTH0C01386g
gene id: 559295:KLTH0C01386g
uniprot id: C5DDJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

559295:KLTH0C04334g
gene id: 559295:KLTH0C04334g
uniprot id: C5DDW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

559295:KLTH0H03916g
gene id: 559295:KLTH0H03916g
uniprot id: C5E2C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

559295:KLTH0E07062g
gene id: 559295:KLTH0E07062g
uniprot id: C5DHT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

559295:KLTH0E13992g
gene id: 559295:KLTH0E13992g
uniprot id: C5DIN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

559295:KLTH0G11792g
gene id: 559295:KLTH0G11792g
uniprot id: C5DMU9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RKM5 family.
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates 60S ribosomal protein L1.

559295:KLTH0G14850g
gene id: 559295:KLTH0G14850g
uniprot id: C5DN80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

559295:KLTH0F08778g
gene id: 559295:KLTH0F08778g
uniprot id: C5DKZ7
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

559295:KLTH0C10428g
gene id: 559295:KLTH0C10428g
uniprot id: C5DEM4
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

559295:KLTH0F14850g
gene id: 559295:KLTH0F14850g
uniprot id: C5DJA5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E04598g
gene id: 559295:KLTH0E04598g
uniprot id: C5DHI5
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

559295:KLTH0D01870g
gene id: 559295:KLTH0D01870g
uniprot id: C5DG25
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

559295:KLTH0G09262g
gene id: 559295:KLTH0G09262g
uniprot id: C5DMI7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

559295:KLTH0E16038g
gene id: 559295:KLTH0E16038g
uniprot id: C5DIY0
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0D13948g
gene id: 559295:KLTH0D13948g
uniprot id: C5DFC2
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

559295:KLTH0F10780g
gene id: 559295:KLTH0F10780g
uniprot id: C5DL82
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D05654g
gene id: 559295:KLTH0D05654g
uniprot id: C5DGI8
names: Function
names: Similarity
messages: Belongs to the MTC2 family.
messages: May be involved in telomere capping.

559295:KLTH0E16676g
gene id: 559295:KLTH0E16676g
uniprot id: C5DJ08
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C10736g
gene id: 559295:KLTH0C10736g
uniprot id: C5DEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

559295:KLTH0B05280g
gene id: 559295:KLTH0B05280g
uniprot id: C5DCR8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

559295:KLTH0C06908g
gene id: 559295:KLTH0C06908g
uniprot id: C5DE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

559295:KLTH0F00858g
gene id: 559295:KLTH0F00858g
uniprot id: C5DK08
names: Similarity
messages: Belongs to the RPAP1 family.

559295:KLTH0A02684g
gene id: 559295:KLTH0A02684g
uniprot id: C5DBH5
names: Similarity
messages: Belongs to the BLM10 family.

559295:KLTH0C10956g
gene id: 559295:KLTH0C10956g
uniprot id: C5DEP6
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0B07370g
gene id: 559295:KLTH0B07370g
uniprot id: C5DD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

559295:KLTH0C10934g
gene id: 559295:KLTH0C10934g
uniprot id: C5DEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

559295:KLTH0D14784g
gene id: 559295:KLTH0D14784g
uniprot id: C5DFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

559295:KLTH0A06292g
gene id: 559295:KLTH0A06292g
uniprot id: C5DBY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

559295:KLTH0F06688g
gene id: 559295:KLTH0F06688g
uniprot id: C5DKQ7
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

559295:KLTH0H03168g
gene id: 559295:KLTH0H03168g
uniprot id: C5E296
names: Similarity
messages: Belongs to the syntaxin family.

559295:KLTH0C00484g
gene id: 559295:KLTH0C00484g
uniprot id: C5DDF0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

559295:KLTH0D11550g
gene id: 559295:KLTH0D11550g
uniprot id: C5DF19
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

559295:KLTH0H16390g
gene id: 559295:KLTH0H16390g
uniprot id: C5E3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VEL1 family.
messages: cytosol

559295:KLTH0B03190g
gene id: 559295:KLTH0B03190g
uniprot id: C5DCH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

559295:KLTH0A02706g
gene id: 559295:KLTH0A02706g
uniprot id: C5DBH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

559295:KLTH0B01804g
gene id: 559295:KLTH0B01804g
uniprot id: C5DCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0D12892g
gene id: 559295:KLTH0D12892g
uniprot id: C5DF79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
messages: nucleolus

559295:KLTH0B06930g
gene id: 559295:KLTH0B06930g
uniprot id: C5DCY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

559295:KLTH0F10230g
gene id: 559295:KLTH0F10230g
uniprot id: C5DL59
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

559295:KLTH0H10252g
gene id: 559295:KLTH0H10252g
uniprot id: C5E343
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

559295:KLTH0C05104g
gene id: 559295:KLTH0C05104g
uniprot id: C5DDZ8
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

559295:KLTH0E16808g
gene id: 559295:KLTH0E16808g
uniprot id: C5DJ13
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G06446g
gene id: 559295:KLTH0G06446g
uniprot id: C5DM70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0G18634g
gene id: 559295:KLTH0G18634g
uniprot id: C5DNN8
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

559295:KLTH0A00748g
gene id: 559295:KLTH0A00748g
uniprot id: C5DB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

559295:KLTH0G15444g
gene id: 559295:KLTH0G15444g
uniprot id: C5DNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F11726g
gene id: 559295:KLTH0F11726g
uniprot id: C5DLC0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

559295:KLTH0A06424g
gene id: 559295:KLTH0A06424g
uniprot id: C5DBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

559295:KLTH0G01980g
gene id: 559295:KLTH0G01980g
uniprot id: C5DLM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).
messages: trans-Golgi network membrane

559295:KLTH0H10780g
gene id: 559295:KLTH0H10780g
uniprot id: C5E367
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0B09900g
gene id: 559295:KLTH0B09900g
uniprot id: C5DDB8
names: Similarity
messages: Belongs to the CWC22 family.

559295:KLTH0D11242g
gene id: 559295:KLTH0D11242g
uniprot id: C5DF05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

559295:KLTH0H09328g
gene id: 559295:KLTH0H09328g
uniprot id: C5E307
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

559295:KLTH0D16192g
gene id: 559295:KLTH0D16192g
uniprot id: C5DFL9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F16434g
gene id: 559295:KLTH0F16434g
uniprot id: C5DJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

559295:KLTH0C07238g
gene id: 559295:KLTH0C07238g
uniprot id: C5DE91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

559295:KLTH0G10494g
gene id: 559295:KLTH0G10494g
uniprot id: C5DMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

559295:KLTH0D15532g
gene id: 559295:KLTH0D15532g
uniprot id: C5DFJ2
names: Similarity
messages: Belongs to the DOCK family.

559295:KLTH0B02662g
gene id: 559295:KLTH0B02662g
uniprot id: C5DCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

559295:KLTH0C03542g
gene id: 559295:KLTH0C03542g
uniprot id: C5DDT0
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

559295:KLTH0G05214g
gene id: 559295:KLTH0G05214g
uniprot id: C5DM17
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

559295:KLTH0G07524g
gene id: 559295:KLTH0G07524g
uniprot id: C5DMB7
names: Similarity
messages: Belongs to the AAA ATPase family.

559295:KLTH0D14498g
gene id: 559295:KLTH0D14498g
uniprot id: C5DFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F00770g
gene id: 559295:KLTH0F00770g
uniprot id: C5DK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

559295:KLTH0H03762g
gene id: 559295:KLTH0H03762g
uniprot id: C5E2C2
names: Similarity
messages: Belongs to the CBP3 family.

559295:KLTH0A04730g
gene id: 559295:KLTH0A04730g
uniprot id: C5DBR3
names: Similarity
messages: Belongs to the SEC6 family.

559295:KLTH0D05984g
gene id: 559295:KLTH0D05984g
uniprot id: C5DGK1
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

559295:KLTH0C03806g
gene id: 559295:KLTH0C03806g
uniprot id: C5DDU2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B03564g
gene id: 559295:KLTH0B03564g
uniprot id: C5DCJ5
names: Similarity
messages: Belongs to the HGH1 family.

559295:KLTH0B07216g
gene id: 559295:KLTH0B07216g
uniprot id: C5DD02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with snRNPs.
messages: Belongs to the SWT21 family.
messages: Involved in mRNA splicing. Helps to stabilize the U1 snRNP-5' splice site interaction (By similarity).
messages: Nucleus

559295:KLTH0E14344g
gene id: 559295:KLTH0E14344g
uniprot id: C5DIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

559295:KLTH0F13266g
gene id: 559295:KLTH0F13266g
uniprot id: C5DJ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

559295:KLTH0F14586g
gene id: 559295:KLTH0F14586g
uniprot id: C5DJ94
names: Similarity
messages: Belongs to the CBF/MAK21 family.

559295:KLTH0G00550g
gene id: 559295:KLTH0G00550g
uniprot id: C5DLG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

559295:KLTH0A00572g
gene id: 559295:KLTH0A00572g
uniprot id: C5DB88
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B02200g
gene id: 559295:KLTH0B02200g
uniprot id: C5DCD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

559295:KLTH0E07260g
gene id: 559295:KLTH0E07260g
uniprot id: C5DHU7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

559295:KLTH0F18854g
gene id: 559295:KLTH0F18854g
uniprot id: C5DJS9
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

559295:KLTH0G10054g
gene id: 559295:KLTH0G10054g
uniprot id: C5DMM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

559295:KLTH0F10098g
gene id: 559295:KLTH0F10098g
uniprot id: C5DL53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

559295:KLTH0H09086g
gene id: 559295:KLTH0H09086g
uniprot id: C5E2Z6
names: Similarity
messages: Belongs to the isochorismatase family.

559295:KLTH0F10406g
gene id: 559295:KLTH0F10406g
uniprot id: C5DL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

559295:KLTH0B00528g
gene id: 559295:KLTH0B00528g
uniprot id: C5DC72
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

559295:KLTH0E10186g
gene id: 559295:KLTH0E10186g
uniprot id: C5DI71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0E12738g
gene id: 559295:KLTH0E12738g
uniprot id: C5DII3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM4 family.
messages: Cytoplasm

559295:KLTH0G17930g
gene id: 559295:KLTH0G17930g
uniprot id: C5DNL1
names: Similarity
messages: Belongs to the AAA ATPase family.

559295:KLTH0D04004g
gene id: 559295:KLTH0D04004g
uniprot id: C5DGB7
names: Similarity
messages: Belongs to the PITHD1 family.

559295:KLTH0B08998g
gene id: 559295:KLTH0B08998g
uniprot id: C5DD78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: nucleolus

559295:KLTH0D03498g
gene id: 559295:KLTH0D03498g
uniprot id: C5DG97
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

559295:KLTH0C09504g
gene id: 559295:KLTH0C09504g
uniprot id: C5DEI5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D04180g
gene id: 559295:KLTH0D04180g
uniprot id: C5DGC5
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F08514g
gene id: 559295:KLTH0F08514g
uniprot id: C5DKY5
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

559295:KLTH0H10824g
gene id: 559295:KLTH0H10824g
uniprot id: C5E369
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

559295:KLTH0C05368g
gene id: 559295:KLTH0C05368g
uniprot id: C5DE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

559295:KLTH0D13090g
gene id: 559295:KLTH0D13090g
uniprot id: C5DF86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

559295:KLTH0A01452g
gene id: 559295:KLTH0A01452g
uniprot id: C5DBC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

559295:KLTH0C09746g
gene id: 559295:KLTH0C09746g
uniprot id: C5DEJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

559295:KLTH0D14806g
gene id: 559295:KLTH0D14806g
uniprot id: C5DFG1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

559295:KLTH0F04444g
gene id: 559295:KLTH0F04444g
uniprot id: C5DKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

559295:KLTH0A01848g
gene id: 559295:KLTH0A01848g
uniprot id: C5DBE1
names: Similarity
messages: Belongs to the peptidase M20A family.

559295:KLTH0C05236g
gene id: 559295:KLTH0C05236g
uniprot id: C5DE04
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

559295:KLTH0E05676g
gene id: 559295:KLTH0E05676g
uniprot id: C5DHN0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E16192g
gene id: 559295:KLTH0E16192g
uniprot id: C5DIY6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

559295:KLTH0F07854g
gene id: 559295:KLTH0F07854g
uniprot id: C5DKV6
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H00836g
gene id: 559295:KLTH0H00836g
uniprot id: C5E1Z3
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

559295:KLTH0H10692g
gene id: 559295:KLTH0H10692g
uniprot id: C5E363
names: Subcellular Location Annotation
messages: nuclear pore complex

559295:KLTH0G04972g
gene id: 559295:KLTH0G04972g
uniprot id: C5DM06
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

559295:KLTH0D10076g
gene id: 559295:KLTH0D10076g
uniprot id: C5DEV5
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

559295:KLTH0C11176g
gene id: 559295:KLTH0C11176g
uniprot id: C5DEQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G18502g
gene id: 559295:KLTH0G18502g
uniprot id: C5DNN2
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

559295:KLTH0F08448g
gene id: 559295:KLTH0F08448g
uniprot id: C5DKY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

559295:KLTH0F11440g
gene id: 559295:KLTH0F11440g
uniprot id: C5DLA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat ASA1 family.
messages: Component of the ASTRA chromatin remodeling machinery complex.
messages: Component of the ASTRA complex involved in chromatin remodeling.
messages: Nucleus

559295:KLTH0F04422g
gene id: 559295:KLTH0F04422g
uniprot id: C5DKG2
names: Similarity
messages: Belongs to the peptidase M20A family.

559295:KLTH0E00682g
gene id: 559295:KLTH0E00682g
uniprot id: C5DH19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

559295:KLTH0F02200g
gene id: 559295:KLTH0F02200g
uniprot id: C5DK68
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

559295:KLTH0E14520g
gene id: 559295:KLTH0E14520g
uniprot id: C5DIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEK2 family.
messages: Binds RNA.
messages: Cytoplasm
messages: Nucleus
messages: P-body
messages: RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).
messages: telomere

559295:KLTH0C03520g
gene id: 559295:KLTH0C03520g
uniprot id: C5DDS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

559295:KLTH0H14410g
gene id: 559295:KLTH0H14410g
uniprot id: C5E3K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

559295:KLTH0D01518g
gene id: 559295:KLTH0D01518g
uniprot id: C5DG10
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

559295:KLTH0B07568g
gene id: 559295:KLTH0B07568g
uniprot id: C5DD17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

559295:KLTH0G03476g
gene id: 559295:KLTH0G03476g
uniprot id: C5DLU0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

559295:KLTH0F05148g
gene id: 559295:KLTH0F05148g
uniprot id: C5DKJ2
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

559295:KLTH0F13310g
gene id: 559295:KLTH0F13310g
uniprot id: C5DJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

559295:KLTH0E04532g
gene id: 559295:KLTH0E04532g
uniprot id: C5DHI2
names: Similarity
messages: Belongs to the peptidase C48 family.

559295:KLTH0H07678g
gene id: 559295:KLTH0H07678g
uniprot id: C5E2U0
names: Similarity
messages: Belongs to the peptidase C19 family.

559295:KLTH0D07920g
gene id: 559295:KLTH0D07920g
uniprot id: C5DGS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

559295:KLTH0H09856g
gene id: 559295:KLTH0H09856g
uniprot id: C5E331
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E00990g
gene id: 559295:KLTH0E00990g
uniprot id: C5DH33
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

559295:KLTH0D11880g
gene id: 559295:KLTH0D11880g
uniprot id: C5DF34
names: Function
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

559295:KLTH0F04620g
gene id: 559295:KLTH0F04620g
uniprot id: C5DKH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

559295:KLTH0G03234g
gene id: 559295:KLTH0G03234g
uniprot id: C5DLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G02970g
gene id: 559295:KLTH0G02970g
uniprot id: C5DLS0
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

559295:KLTH0B08492g
gene id: 559295:KLTH0B08492g
uniprot id: C5DD58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

559295:KLTH0C05742g
gene id: 559295:KLTH0C05742g
uniprot id: C5DE25
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

559295:KLTH0D01848g
gene id: 559295:KLTH0D01848g
uniprot id: C5DG24
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

559295:KLTH0G16478g
gene id: 559295:KLTH0G16478g
uniprot id: C5DNF2
names: Similarity
messages: Belongs to the UPF0045 family.

559295:KLTH0H15752g
gene id: 559295:KLTH0H15752g
uniprot id: C5E3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

559295:KLTH0E06974g
gene id: 559295:KLTH0E06974g
uniprot id: C5DHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRG family.
messages: Nucleus

559295:KLTH0F08998g
gene id: 559295:KLTH0F08998g
uniprot id: C5DL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS35 family.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

559295:KLTH0E10560g
gene id: 559295:KLTH0E10560g
uniprot id: C5DI87
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0H08470g
gene id: 559295:KLTH0H08470g
uniprot id: C5E2X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

559295:KLTH0B08250g
gene id: 559295:KLTH0B08250g
uniprot id: C5DD47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

559295:KLTH0E08602g
gene id: 559295:KLTH0E08602g
uniprot id: C5DI02
names: Subcellular Location Annotation
messages: Peroxisome membrane

559295:KLTH0G02530g
gene id: 559295:KLTH0G02530g
uniprot id: C5DLQ0
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D08800g
gene id: 559295:KLTH0D08800g
uniprot id: C5DGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

559295:KLTH0C09768g
gene id: 559295:KLTH0C09768g
uniprot id: C5DEJ4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0B01980g
gene id: 559295:KLTH0B01980g
uniprot id: C5DCC8
names: Similarity
messages: Belongs to the MEMO1 family.

559295:KLTH0E09702g
gene id: 559295:KLTH0E09702g
uniprot id: C5DI49
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

559295:KLTH0E12298g
gene id: 559295:KLTH0E12298g
uniprot id: C5DIG3
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

559295:KLTH0D08470g
gene id: 559295:KLTH0D08470g
uniprot id: C5DGU9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEF1 family.
messages: Cytoplasm
messages: Homodimer; may form higher order oligomers. Interacts with the large RNA polymerase II subunit RPO21; the interaction is direct and serves to bridge RPO21 to the Elongin complex in a manner dependent on transcription stress. Interacts with RAD26.
messages: Nucleus
messages: Proteolytically cleaved by the proteasome in response to transcription stress; the resulting N-terminal form constitutes the activated nuclear form and the C-terminal portion is degraded.
messages: Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation. Binds DNA.
messages: Ubiquitinated.
messages: telomere

559295:KLTH0D05720g
gene id: 559295:KLTH0D05720g
uniprot id: C5DGJ1
names: Similarity
messages: Belongs to the CWC16 family.

559295:KLTH0A05808g
gene id: 559295:KLTH0A05808g
uniprot id: C5DBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F06358g
gene id: 559295:KLTH0F06358g
uniprot id: C5DKP3
names: Similarity
messages: Belongs to the SUN family.

559295:KLTH0D04796g
gene id: 559295:KLTH0D04796g
uniprot id: C5DGF0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

559295:KLTH0D02860g
gene id: 559295:KLTH0D02860g
uniprot id: C5DG70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

559295:KLTH0D02926g
gene id: 559295:KLTH0D02926g
uniprot id: C5DG73
names: Similarity
messages: Belongs to the FUN14 family.

559295:KLTH0A06798g
gene id: 559295:KLTH0A06798g
uniprot id: C5DC04
names: Similarity
messages: Belongs to the PPP phosphatase family.

559295:KLTH0G14388g
gene id: 559295:KLTH0G14388g
uniprot id: C5DN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

559295:KLTH0C10648g
gene id: 559295:KLTH0C10648g
uniprot id: C5DEN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0F08118g
gene id: 559295:KLTH0F08118g
uniprot id: C5DKW7
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

559295:KLTH0B03080g
gene id: 559295:KLTH0B03080g
uniprot id: C5DCH3
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F09878g
gene id: 559295:KLTH0F09878g
uniprot id: C5DL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP2 family.
messages: Membrane
messages: Peroxisome membrane

559295:KLTH0H13530g
gene id: 559295:KLTH0H13530g
uniprot id: C5E3H1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

559295:KLTH0A00462g
gene id: 559295:KLTH0A00462g
uniprot id: C5DB83
names: Similarity
messages: Belongs to the IUNH family.

559295:KLTH0F06754g
gene id: 559295:KLTH0F06754g
uniprot id: C5DKR0
names: Similarity
messages: Belongs to the peptidase A1 family.

559295:KLTH0D08866g
gene id: 559295:KLTH0D08866g
uniprot id: C5DGW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

559295:KLTH0F06864g
gene id: 559295:KLTH0F06864g
uniprot id: C5DKR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0H04818g
gene id: 559295:KLTH0H04818g
uniprot id: C5E2G7
names: Similarity
messages: Belongs to the NAD kinase family.

559295:KLTH0F19316g
gene id: 559295:KLTH0F19316g
uniprot id: C5DJV0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G02464g
gene id: 559295:KLTH0G02464g
uniprot id: C5DLP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

559295:KLTH0G10934g
gene id: 559295:KLTH0G10934g
uniprot id: C5DMR0
names: Similarity
messages: Belongs to the peptidase C19 family.

559295:KLTH0G19140g
gene id: 559295:KLTH0G19140g
uniprot id: C5DNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

559295:KLTH0F15576g
gene id: 559295:KLTH0F15576g
uniprot id: C5DJD6
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

559295:KLTH0H00572g
gene id: 559295:KLTH0H00572g
uniprot id: C5E1Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
messages: Homodimer.
messages: Preautophagosomal structure

559295:KLTH0D12034g
gene id: 559295:KLTH0D12034g
uniprot id: C5DF41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

559295:KLTH0B08756g
gene id: 559295:KLTH0B08756g
uniprot id: C5DD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

559295:KLTH0D11176g
gene id: 559295:KLTH0D11176g
uniprot id: C5DF02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

559295:KLTH0D04840g
gene id: 559295:KLTH0D04840g
uniprot id: C5DGF2
names: Similarity
messages: Belongs to the RRN3 family.

559295:KLTH0H12980g
gene id: 559295:KLTH0H12980g
uniprot id: C5E3F4
names: Similarity
messages: Belongs to the SH3YL1 family.

559295:KLTH0E06204g
gene id: 559295:KLTH0E06204g
uniprot id: C5DHQ4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

559295:KLTH0B07876g
gene id: 559295:KLTH0B07876g
uniprot id: C5DD31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

559295:KLTH0D15840g
gene id: 559295:KLTH0D15840g
uniprot id: C5DFK4
names: Similarity
messages: Belongs to the WD repeat coronin family.

559295:KLTH0B00858g
gene id: 559295:KLTH0B00858g
uniprot id: C5DC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0D09702g
gene id: 559295:KLTH0D09702g
uniprot id: C5DET9
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

559295:KLTH0H09724g
gene id: 559295:KLTH0H09724g
uniprot id: C5E325
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

559295:KLTH0B06094g
gene id: 559295:KLTH0B06094g
uniprot id: C5DCV4
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

559295:KLTH0E14872g
gene id: 559295:KLTH0E14872g
uniprot id: C5DIS8
names: Similarity
messages: Belongs to the small Tim family.

559295:KLTH0G00924g
gene id: 559295:KLTH0G00924g
uniprot id: C5DLI2
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

559295:KLTH0C09944g
gene id: 559295:KLTH0C09944g
uniprot id: C5DEK2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A03344g
gene id: 559295:KLTH0A03344g
uniprot id: C5DBK4
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

559295:KLTH0G14344g
gene id: 559295:KLTH0G14344g
uniprot id: C5DN57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

559295:KLTH0G06072g
gene id: 559295:KLTH0G06072g
uniprot id: C5DM53
names: Similarity
messages: Belongs to the ATPase delta chain family.

559295:KLTH0F12936g
gene id: 559295:KLTH0F12936g
uniprot id: C5DJ26
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

559295:KLTH0C05874g
gene id: 559295:KLTH0C05874g
uniprot id: C5DE31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F09988g
gene id: 559295:KLTH0F09988g
uniprot id: C5DL50
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

559295:KLTH0D14124g
gene id: 559295:KLTH0D14124g
uniprot id: C5DFD0
names: Similarity
messages: Belongs to the RAD52 family.

559295:KLTH0H09350g
gene id: 559295:KLTH0H09350g
uniprot id: C5E308
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

559295:KLTH0E12760g
gene id: 559295:KLTH0E12760g
uniprot id: C5DII4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0H11396g
gene id: 559295:KLTH0H11396g
uniprot id: C5E392
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F19250g
gene id: 559295:KLTH0F19250g
uniprot id: C5DJU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F02926g
gene id: 559295:KLTH0F02926g
uniprot id: C5DKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: Cytoplasm
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

559295:KLTH0C00352g
gene id: 559295:KLTH0C00352g
uniprot id: C5DDE4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H00220g
gene id: 559295:KLTH0H00220g
uniprot id: C5E1W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0D05104g
gene id: 559295:KLTH0D05104g
uniprot id: C5DGG3
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

559295:KLTH0G08624g
gene id: 559295:KLTH0G08624g
uniprot id: C5DMG1
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

559295:KLTH0E11308g
gene id: 559295:KLTH0E11308g
uniprot id: C5DIB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

559295:KLTH0D17864g
gene id: 559295:KLTH0D17864g
uniprot id: C5DFT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

559295:KLTH0E07590g
gene id: 559295:KLTH0E07590g
uniprot id: C5DHW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

559295:KLTH0A04598g
gene id: 559295:KLTH0A04598g
uniprot id: C5DBQ7
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

559295:KLTH0D08052g
gene id: 559295:KLTH0D08052g
uniprot id: C5DGT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BLI1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1).
messages: Endosome

559295:KLTH0C03894g
gene id: 559295:KLTH0C03894g
uniprot id: C5DDU6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

559295:KLTH0C09834g
gene id: 559295:KLTH0C09834g
uniprot id: C5DEJ7
names: Similarity
messages: Belongs to the VPS72/YL1 family.

559295:KLTH0D01100g
gene id: 559295:KLTH0D01100g
uniprot id: C5DFZ2
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F19382g
gene id: 559295:KLTH0F19382g
uniprot id: C5DJV3
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

559295:KLTH0C08184g
gene id: 559295:KLTH0C08184g
uniprot id: C5DED0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

559295:KLTH0H15840g
gene id: 559295:KLTH0H15840g
uniprot id: C5E3S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSW5 family.
messages: Involved in spore wall assembly.
messages: Membrane

559295:KLTH0H11110g
gene id: 559295:KLTH0H11110g
uniprot id: C5E382
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

559295:KLTH0H12254g
gene id: 559295:KLTH0H12254g
uniprot id: C5E3C7
names: Similarity
messages: Belongs to the DCC1 family.

559295:KLTH0A00770g
gene id: 559295:KLTH0A00770g
uniprot id: C5DB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

559295:KLTH0G15378g
gene id: 559295:KLTH0G15378g
uniprot id: C5DNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

559295:KLTH0G10032g
gene id: 559295:KLTH0G10032g
uniprot id: C5DMM1
names: Similarity
messages: Belongs to the SHQ1 family.

559295:KLTH0H06930g
gene id: 559295:KLTH0H06930g
uniprot id: C5E2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRI1 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0H01518g
gene id: 559295:KLTH0H01518g
uniprot id: C5E221
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: nuclear pore complex

559295:KLTH0G01100g
gene id: 559295:KLTH0G01100g
uniprot id: C5DLJ0
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

559295:KLTH0E14542g
gene id: 559295:KLTH0E14542g
uniprot id: C5DIR3
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

559295:KLTH0F09746g
gene id: 559295:KLTH0F09746g
uniprot id: C5DL40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

559295:KLTH0F03652g
gene id: 559295:KLTH0F03652g
uniprot id: C5DKD0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G01562g
gene id: 559295:KLTH0G01562g
uniprot id: C5DLL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

559295:KLTH0E05632g
gene id: 559295:KLTH0E05632g
uniprot id: C5DHM8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

559295:KLTH0G19338g
gene id: 559295:KLTH0G19338g
uniprot id: C5DNS0
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

559295:KLTH0F15950g
gene id: 559295:KLTH0F15950g
uniprot id: C5DJF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

559295:KLTH0G02310g
gene id: 559295:KLTH0G02310g
uniprot id: C5DLP1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B01364g
gene id: 559295:KLTH0B01364g
uniprot id: C5DCA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

559295:KLTH0G11198g
gene id: 559295:KLTH0G11198g
uniprot id: C5DMS2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

559295:KLTH0H03234g
gene id: 559295:KLTH0H03234g
uniprot id: C5E299
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

559295:KLTH0B10142g
gene id: 559295:KLTH0B10142g
uniprot id: C5DDC6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F01584g
gene id: 559295:KLTH0F01584g
uniprot id: C5DK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0D14146g
gene id: 559295:KLTH0D14146g
uniprot id: C5DFD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0G07392g
gene id: 559295:KLTH0G07392g
uniprot id: C5DMB1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

559295:KLTH0C11550g
gene id: 559295:KLTH0C11550g
uniprot id: C5DER8
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F05676g
gene id: 559295:KLTH0F05676g
uniprot id: C5DKL4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

559295:KLTH0E02552g
gene id: 559295:KLTH0E02552g
uniprot id: C5DHA0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

559295:KLTH0F04202g
gene id: 559295:KLTH0F04202g
uniprot id: C5DKF3
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

559295:KLTH0C11220g
gene id: 559295:KLTH0C11220g
uniprot id: C5DEQ4
names: Similarity
messages: Belongs to the SGT family.

559295:KLTH0A02090g
gene id: 559295:KLTH0A02090g
uniprot id: C5DBF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

559295:KLTH0C10296g
gene id: 559295:KLTH0C10296g
uniprot id: C5DEL8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

559295:KLTH0F05566g
gene id: 559295:KLTH0F05566g
uniprot id: C5DKK9
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

559295:KLTH0H06512g
gene id: 559295:KLTH0H06512g
uniprot id: C5E2N9
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

559295:KLTH0D17336g
gene id: 559295:KLTH0D17336g
uniprot id: C5DFR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

559295:KLTH0G07304g
gene id: 559295:KLTH0G07304g
uniprot id: C5DMA7
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

559295:KLTH0F09174g
gene id: 559295:KLTH0F09174g
uniprot id: C5DL14
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

559295:KLTH0F10340g
gene id: 559295:KLTH0F10340g
uniprot id: C5DL64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

559295:KLTH0D02706g
gene id: 559295:KLTH0D02706g
uniprot id: C5DG63
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

559295:KLTH0H01936g
gene id: 559295:KLTH0H01936g
uniprot id: C5E240
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A05632g
gene id: 559295:KLTH0A05632g
uniprot id: C5DBV4
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition.

559295:KLTH0B10186g
gene id: 559295:KLTH0B10186g
uniprot id: C5DDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

559295:KLTH0F17578g
gene id: 559295:KLTH0F17578g
uniprot id: C5DJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

559295:KLTH0C02332g
gene id: 559295:KLTH0C02332g
uniprot id: C5DDN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

559295:KLTH0F13662g
gene id: 559295:KLTH0F13662g
uniprot id: C5DJ56
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E02926g
gene id: 559295:KLTH0E02926g
uniprot id: C5DHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

559295:KLTH0E02860g
gene id: 559295:KLTH0E02860g
uniprot id: C5DHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

559295:KLTH0B08800g
gene id: 559295:KLTH0B08800g
uniprot id: C5DD70
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

559295:KLTH0F13772g
gene id: 559295:KLTH0F13772g
uniprot id: C5DJ60
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D06820g
gene id: 559295:KLTH0D06820g
uniprot id: C5DGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0G13464g
gene id: 559295:KLTH0G13464g
uniprot id: C5DN19
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C04818g
gene id: 559295:KLTH0C04818g
uniprot id: C5DDY5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0H06072g
gene id: 559295:KLTH0H06072g
uniprot id: C5E2M1
names: Function
names: Similarity
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

559295:KLTH0D10120g
gene id: 559295:KLTH0D10120g
uniprot id: C5DEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

559295:KLTH0G09174g
gene id: 559295:KLTH0G09174g
uniprot id: C5DMI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

559295:KLTH0D06446g
gene id: 559295:KLTH0D06446g
uniprot id: C5DGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

559295:KLTH0G16016g
gene id: 559295:KLTH0G16016g
uniprot id: C5DND2
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

559295:KLTH0D13596g
gene id: 559295:KLTH0D13596g
uniprot id: C5DFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

559295:KLTH0A07062g
gene id: 559295:KLTH0A07062g
uniprot id: C5DC16
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

559295:KLTH0D08536g
gene id: 559295:KLTH0D08536g
uniprot id: C5DGV2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D09196g
gene id: 559295:KLTH0D09196g
uniprot id: C5DGY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for an H2A variant leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

559295:KLTH0E03102g
gene id: 559295:KLTH0E03102g
uniprot id: C5DHC2
names: Similarity
messages: Belongs to the DSD1 family.

559295:KLTH0F04048g
gene id: 559295:KLTH0F04048g
uniprot id: C5DKE6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G11748g
gene id: 559295:KLTH0G11748g
uniprot id: C5DMU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

559295:KLTH0D05588g
gene id: 559295:KLTH0D05588g
uniprot id: C5DGI5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0G15246g
gene id: 559295:KLTH0G15246g
uniprot id: C5DN98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

559295:KLTH0C03278g
gene id: 559295:KLTH0C03278g
uniprot id: C5DDR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

559295:KLTH0F06974g
gene id: 559295:KLTH0F06974g
uniprot id: C5DKR9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

559295:KLTH0G03102g
gene id: 559295:KLTH0G03102g
uniprot id: C5DLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

559295:KLTH0C01782g
gene id: 559295:KLTH0C01782g
uniprot id: C5DDK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0F11968g
gene id: 559295:KLTH0F11968g
uniprot id: C5DLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

559295:KLTH0D16874g
gene id: 559295:KLTH0D16874g
uniprot id: C5DFP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

559295:KLTH0G10406g
gene id: 559295:KLTH0G10406g
uniprot id: C5DMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

559295:KLTH0D12452g
gene id: 559295:KLTH0D12452g
uniprot id: C5DF59
names: Similarity
messages: Belongs to the CEF1 family.

559295:KLTH0C04906g
gene id: 559295:KLTH0C04906g
uniprot id: C5DDY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

559295:KLTH0H10472g
gene id: 559295:KLTH0H10472g
uniprot id: C5E353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM54 family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0E13508g
gene id: 559295:KLTH0E13508g
uniprot id: C5DIL7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G01892g
gene id: 559295:KLTH0G01892g
uniprot id: C5DLM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

559295:KLTH0G10780g
gene id: 559295:KLTH0G10780g
uniprot id: C5DMQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

559295:KLTH0F08492g
gene id: 559295:KLTH0F08492g
uniprot id: C5DKY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

559295:KLTH0H02706g
gene id: 559295:KLTH0H02706g
uniprot id: C5E275
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

559295:KLTH0B05104g
gene id: 559295:KLTH0B05104g
uniprot id: C5DCR0
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

559295:KLTH0E13310g
gene id: 559295:KLTH0E13310g
uniprot id: C5DIK8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

559295:KLTH0E13530g
gene id: 559295:KLTH0E13530g
uniprot id: C5DIL8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

559295:KLTH0D17248g
gene id: 559295:KLTH0D17248g
uniprot id: C5DFR3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

559295:KLTH0F01672g
gene id: 559295:KLTH0F01672g
uniprot id: C5DK45
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

559295:KLTH0D05038g
gene id: 559295:KLTH0D05038g
uniprot id: C5DGG0
names: Similarity
messages: Belongs to the p23/wos2 family.

559295:KLTH0D17908g
gene id: 559295:KLTH0D17908g
uniprot id: C5DFU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

559295:KLTH0F15378g
gene id: 559295:KLTH0F15378g
uniprot id: C5DJC7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

559295:KLTH0G07436g
gene id: 559295:KLTH0G07436g
uniprot id: C5DMB3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

559295:KLTH0E15554g
gene id: 559295:KLTH0E15554g
uniprot id: C5DIV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

559295:KLTH0E07194g
gene id: 559295:KLTH0E07194g
uniprot id: C5DHU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCM1 family.
messages: Mitochondrion
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).

559295:KLTH0H14476g
gene id: 559295:KLTH0H14476g
uniprot id: C5E3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

559295:KLTH0D13684g
gene id: 559295:KLTH0D13684g
uniprot id: C5DFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

559295:KLTH0C05984g
gene id: 559295:KLTH0C05984g
uniprot id: C5DE36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

559295:KLTH0A07964g
gene id: 559295:KLTH0A07964g
uniprot id: C5DC51
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B03652g
gene id: 559295:KLTH0B03652g
uniprot id: C5DCJ9
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

559295:KLTH0E05324g
gene id: 559295:KLTH0E05324g
uniprot id: C5DHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0H00550g
gene id: 559295:KLTH0H00550g
uniprot id: C5E1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus

559295:KLTH0E12914g
gene id: 559295:KLTH0E12914g
uniprot id: C5DIJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

559295:KLTH0A01342g
gene id: 559295:KLTH0A01342g
uniprot id: C5DBC2
names: Similarity
messages: Belongs to the MON2 family.

559295:KLTH0G01342g
gene id: 559295:KLTH0G01342g
uniprot id: C5DLK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

559295:KLTH0G06116g
gene id: 559295:KLTH0G06116g
uniprot id: C5DM55
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.

559295:KLTH0C06028g
gene id: 559295:KLTH0C06028g
uniprot id: C5DE38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

559295:KLTH0E10450g
gene id: 559295:KLTH0E10450g
uniprot id: C5DI82
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

559295:KLTH0G03498g
gene id: 559295:KLTH0G03498g
uniprot id: C5DLU1
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

559295:KLTH0D00198g
gene id: 559295:KLTH0D00198g
uniprot id: C5DFV5
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

559295:KLTH0B05940g
gene id: 559295:KLTH0B05940g
uniprot id: C5DCU7
names: Similarity
messages: Belongs to the actin family.

559295:KLTH0C03146g
gene id: 559295:KLTH0C03146g
uniprot id: C5DDR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

559295:KLTH0F07128g
gene id: 559295:KLTH0F07128g
uniprot id: C5DKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

559295:KLTH0F10604g
gene id: 559295:KLTH0F10604g
uniprot id: C5DL74
names: Function
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

559295:KLTH0C08052g
gene id: 559295:KLTH0C08052g
uniprot id: C5DEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0G05720g
gene id: 559295:KLTH0G05720g
uniprot id: C5DM38
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

559295:KLTH0F00132g
gene id: 559295:KLTH0F00132g
uniprot id: C5DJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.
messages: Secreted

559295:KLTH0D11198g
gene id: 559295:KLTH0D11198g
uniprot id: C5DF03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

559295:KLTH0D12782g
gene id: 559295:KLTH0D12782g
uniprot id: C5DF74
names: Similarity
messages: Belongs to the phosducin family.

559295:KLTH0B09460g
gene id: 559295:KLTH0B09460g
uniprot id: C5DD99
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

559295:KLTH0H15884g
gene id: 559295:KLTH0H15884g
uniprot id: C5E3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Mitochondrion inner membrane

559295:KLTH0F16368g
gene id: 559295:KLTH0F16368g
uniprot id: C5DJH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

559295:KLTH0D17094g
gene id: 559295:KLTH0D17094g
uniprot id: C5DFQ6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0G11770g
gene id: 559295:KLTH0G11770g
uniprot id: C5DMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

559295:KLTH0D10516g
gene id: 559295:KLTH0D10516g
uniprot id: C5DEX4
names: Similarity
messages: Belongs to the MTFP1 family.

559295:KLTH0F13332g
gene id: 559295:KLTH0F13332g
uniprot id: C5DJ42
names: Similarity
messages: Belongs to the SEC3 family.

559295:KLTH0B00990g
gene id: 559295:KLTH0B00990g
uniprot id: C5DC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

559295:KLTH0H05280g
gene id: 559295:KLTH0H05280g
uniprot id: C5E2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0B08470g
gene id: 559295:KLTH0B08470g
uniprot id: C5DD57
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

559295:KLTH0B01650g
gene id: 559295:KLTH0B01650g
uniprot id: C5DCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

559295:KLTH0D11264g
gene id: 559295:KLTH0D11264g
uniprot id: C5DF06
names: Similarity
messages: Belongs to the peptidase A1 family.

559295:KLTH0C05324g
gene id: 559295:KLTH0C05324g
uniprot id: C5DE07
names: Similarity
messages: Belongs to the actin family.

559295:KLTH0D13860g
gene id: 559295:KLTH0D13860g
uniprot id: C5DFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

559295:KLTH0H01562g
gene id: 559295:KLTH0H01562g
uniprot id: C5E223
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0C06006g
gene id: 559295:KLTH0C06006g
uniprot id: C5DE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

559295:KLTH0D17842g
gene id: 559295:KLTH0D17842g
uniprot id: C5DFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0G06270g
gene id: 559295:KLTH0G06270g
uniprot id: C5DM62
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.

559295:KLTH0F01188g
gene id: 559295:KLTH0F01188g
uniprot id: C5DK23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

559295:KLTH0H03102g
gene id: 559295:KLTH0H03102g
uniprot id: C5E293
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

559295:KLTH0D15268g
gene id: 559295:KLTH0D15268g
uniprot id: C5DFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

559295:KLTH0B00440g
gene id: 559295:KLTH0B00440g
uniprot id: C5DC68
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B02310g
gene id: 559295:KLTH0B02310g
uniprot id: C5DCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

559295:KLTH0A01672g
gene id: 559295:KLTH0A01672g
uniprot id: C5DBD5
names: Similarity
messages: Belongs to the CNOT9 family.

559295:KLTH0B07986g
gene id: 559295:KLTH0B07986g
uniprot id: C5DD36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

559295:KLTH0E16984g
gene id: 559295:KLTH0E16984g
uniprot id: C5DJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0F12056g
gene id: 559295:KLTH0F12056g
uniprot id: C5DLD4
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

559295:KLTH0F15510g
gene id: 559295:KLTH0F15510g
uniprot id: C5DJD3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

559295:KLTH0B01606g
gene id: 559295:KLTH0B01606g
uniprot id: C5DCB1
names: Similarity
messages: Belongs to the IlvD/Edd family.

559295:KLTH0D00638g
gene id: 559295:KLTH0D00638g
uniprot id: C5DFX1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

559295:KLTH0E01298g
gene id: 559295:KLTH0E01298g
uniprot id: C5DH47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

559295:KLTH0B03916g
gene id: 559295:KLTH0B03916g
uniprot id: C5DCL0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THI4 family.
messages: Binds 1 Fe cation per subunit.
messages: Cytoplasm
messages: During the catalytic reaction, a sulfide is transferred from Cys-204 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
messages: Nucleus

559295:KLTH0B04026g
gene id: 559295:KLTH0B04026g
uniprot id: C5DCL4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D11154g
gene id: 559295:KLTH0D11154g
uniprot id: C5DF01
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

559295:KLTH0G12166g
gene id: 559295:KLTH0G12166g
uniprot id: C5DMW3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX4 family.
messages: Forms a heterodimer with SLX1.
messages: Nucleus
messages: Phosphorylated in response to DNA damage.
messages: Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.

559295:KLTH0D03344g
gene id: 559295:KLTH0D03344g
uniprot id: C5DG90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

559295:KLTH0F12958g
gene id: 559295:KLTH0F12958g
uniprot id: C5DJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

559295:KLTH0C11330g
gene id: 559295:KLTH0C11330g
uniprot id: C5DEQ9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

559295:KLTH0D03322g
gene id: 559295:KLTH0D03322g
uniprot id: C5DG89
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

559295:KLTH0H08668g
gene id: 559295:KLTH0H08668g
uniprot id: C5E2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

559295:KLTH0G11880g
gene id: 559295:KLTH0G11880g
uniprot id: C5DMV2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

559295:KLTH0H13816g
gene id: 559295:KLTH0H13816g
uniprot id: C5E3I4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0G14674g
gene id: 559295:KLTH0G14674g
uniprot id: C5DN72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0E13266g
gene id: 559295:KLTH0E13266g
uniprot id: C5DIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0F05654g
gene id: 559295:KLTH0F05654g
uniprot id: C5DKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

559295:KLTH0D01826g
gene id: 559295:KLTH0D01826g
uniprot id: C5DG23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

559295:KLTH0F11242g
gene id: 559295:KLTH0F11242g
uniprot id: C5DL99
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.

559295:KLTH0F10296g
gene id: 559295:KLTH0F10296g
uniprot id: C5DL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP14 family.
messages: Cytoplasm

559295:KLTH0H07062g
gene id: 559295:KLTH0H07062g
uniprot id: C5E2R3
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

559295:KLTH0H05676g
gene id: 559295:KLTH0H05676g
uniprot id: C5E2K3
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

559295:KLTH0G17204g
gene id: 559295:KLTH0G17204g
uniprot id: C5DNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

559295:KLTH0H09262g
gene id: 559295:KLTH0H09262g
uniprot id: C5E304
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

559295:KLTH0E06710g
gene id: 559295:KLTH0E06710g
uniprot id: C5DHS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

559295:KLTH0G16236g
gene id: 559295:KLTH0G16236g
uniprot id: C5DMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0F08690g
gene id: 559295:KLTH0F08690g
uniprot id: C5DKZ3
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

559295:KLTH0F02222g
gene id: 559295:KLTH0F02222g
uniprot id: C5DK69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

559295:KLTH0H02222g
gene id: 559295:KLTH0H02222g
uniprot id: C5E253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

559295:KLTH0F09284g
gene id: 559295:KLTH0F09284g
uniprot id: C5DL19
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

559295:KLTH0B04070g
gene id: 559295:KLTH0B04070g
uniprot id: C5DCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

559295:KLTH0E05390g
gene id: 559295:KLTH0E05390g
uniprot id: C5DHL7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G05654g
gene id: 559295:KLTH0G05654g
uniprot id: C5DM35
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

559295:KLTH0F03850g
gene id: 559295:KLTH0F03850g
uniprot id: C5DKD9
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

559295:KLTH0F12848g
gene id: 559295:KLTH0F12848g
uniprot id: C5DJ22
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E16104g
gene id: 559295:KLTH0E16104g
uniprot id: C5DIY3
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0B07062g
gene id: 559295:KLTH0B07062g
uniprot id: C5DCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

559295:KLTH0E04026g
gene id: 559295:KLTH0E04026g
uniprot id: C5DHF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0E10164g
gene id: 559295:KLTH0E10164g
uniprot id: C5DI70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

559295:KLTH0B07744g
gene id: 559295:KLTH0B07744g
uniprot id: C5DD25
names: Similarity
messages: Belongs to the heat shock protein 70 family.

559295:KLTH0H03190g
gene id: 559295:KLTH0H03190g
uniprot id: C5E297
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

559295:KLTH0B01496g
gene id: 559295:KLTH0B01496g
uniprot id: C5DCA6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

559295:KLTH0E14322g
gene id: 559295:KLTH0E14322g
uniprot id: C5DIQ3
names: Similarity
messages: Belongs to the CBF/MAK21 family.

559295:KLTH0F19866g
gene id: 559295:KLTH0F19866g
uniprot id: C5DJX5
names: Similarity
messages: Belongs to the globin family.

559295:KLTH0A04202g
gene id: 559295:KLTH0A04202g
uniprot id: C5DBP0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

559295:KLTH0A00968g
gene id: 559295:KLTH0A00968g
uniprot id: C5DBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Membrane

559295:KLTH0G10978g
gene id: 559295:KLTH0G10978g
uniprot id: C5DMR2
names: Similarity
messages: Belongs to the frataxin family.

559295:KLTH0F14410g
gene id: 559295:KLTH0F14410g
uniprot id: C5DJ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

559295:KLTH0B08668g
gene id: 559295:KLTH0B08668g
uniprot id: C5DD65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

559295:KLTH0F04774g
gene id: 559295:KLTH0F04774g
uniprot id: C5DKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

559295:KLTH0F11836g
gene id: 559295:KLTH0F11836g
uniprot id: C5DLC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

559295:KLTH0F05786g
gene id: 559295:KLTH0F05786g
uniprot id: C5DKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G11418g
gene id: 559295:KLTH0G11418g
uniprot id: C5DMT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

559295:KLTH0D06688g
gene id: 559295:KLTH0D06688g
uniprot id: C5DGN2
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

559295:KLTH0F10758g
gene id: 559295:KLTH0F10758g
uniprot id: C5DL81
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

559295:KLTH0F16720g
gene id: 559295:KLTH0F16720g
uniprot id: C5DJI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0A06556g
gene id: 559295:KLTH0A06556g
uniprot id: C5DBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

559295:KLTH0D12056g
gene id: 559295:KLTH0D12056g
uniprot id: C5DF42
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

559295:KLTH0C02728g
gene id: 559295:KLTH0C02728g
uniprot id: C5DDP8
names: Similarity
messages: Belongs to the thymidylate kinase family.

559295:KLTH0A07370g
gene id: 559295:KLTH0A07370g
uniprot id: C5DC30
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H03388g
gene id: 559295:KLTH0H03388g
uniprot id: C5E2A5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G07634g
gene id: 559295:KLTH0G07634g
uniprot id: C5DMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

559295:KLTH0D09086g
gene id: 559295:KLTH0D09086g
uniprot id: C5DGX6
names: Similarity
messages: Belongs to the syntaxin family.

559295:KLTH0H05060g
gene id: 559295:KLTH0H05060g
uniprot id: C5E2H8
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

559295:KLTH0C07282g
gene id: 559295:KLTH0C07282g
uniprot id: C5DE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Membrane

559295:KLTH0E11682g
gene id: 559295:KLTH0E11682g
uniprot id: C5DID6
names: Similarity
messages: Belongs to the CWC21 family.

559295:KLTH0E00264g
gene id: 559295:KLTH0E00264g
uniprot id: C5DH03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

559295:KLTH0A07084g
gene id: 559295:KLTH0A07084g
uniprot id: C5DC17
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0E11748g
gene id: 559295:KLTH0E11748g
uniprot id: C5DID9
names: Similarity
messages: Belongs to the TTC4 family.

559295:KLTH0A02992g
gene id: 559295:KLTH0A02992g
uniprot id: C5DBI9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

559295:KLTH0H07788g
gene id: 559295:KLTH0H07788g
uniprot id: C5E2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

559295:KLTH0A02222g
gene id: 559295:KLTH0A02222g
uniprot id: C5DBF6
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

559295:KLTH0F16764g
gene id: 559295:KLTH0F16764g
uniprot id: C5DJI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

559295:KLTH0D07436g
gene id: 559295:KLTH0D07436g
uniprot id: C5DGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

559295:KLTH0H04026g
gene id: 559295:KLTH0H04026g
uniprot id: C5E2D4
names: Similarity
messages: Belongs to the TYW1 family.

559295:KLTH0D00968g
gene id: 559295:KLTH0D00968g
uniprot id: C5DFY6
names: Similarity
messages: Belongs to the BolA/IbaG family.

559295:KLTH0D08602g
gene id: 559295:KLTH0D08602g
uniprot id: C5DGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

559295:KLTH0E06094g
gene id: 559295:KLTH0E06094g
uniprot id: C5DHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G07942g
gene id: 559295:KLTH0G07942g
uniprot id: C5DMD4
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

559295:KLTH0F17204g
gene id: 559295:KLTH0F17204g
uniprot id: C5DJK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETT1 family.
messages: Nucleus
messages: Required for correct translation termination and probably involved in regulation of hypoxic gene expression.

559295:KLTH0H15620g
gene id: 559295:KLTH0H15620g
uniprot id: C5E3R0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

559295:KLTH0D08822g
gene id: 559295:KLTH0D08822g
uniprot id: C5DGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

559295:KLTH0A05236g
gene id: 559295:KLTH0A05236g
uniprot id: C5DBT6
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

559295:KLTH0D05346g
gene id: 559295:KLTH0D05346g
uniprot id: C5DGH4
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0F05852g
gene id: 559295:KLTH0F05852g
uniprot id: C5DKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM23 family.
messages: Mitochondrion

559295:KLTH0H12474g
gene id: 559295:KLTH0H12474g
uniprot id: C5E3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

559295:KLTH0D08624g
gene id: 559295:KLTH0D08624g
uniprot id: C5DGV6
names: Similarity
messages: Belongs to the actin family.

559295:KLTH0D15356g
gene id: 559295:KLTH0D15356g
uniprot id: C5DFI4
names: Similarity
messages: Belongs to the CDC73 family.

559295:KLTH0G16214g
gene id: 559295:KLTH0G16214g
uniprot id: C5DNE1
names: Similarity
messages: Belongs to the TCP11 family.

559295:KLTH0E05742g
gene id: 559295:KLTH0E05742g
uniprot id: C5DHN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

559295:KLTH0H05962g
gene id: 559295:KLTH0H05962g
uniprot id: C5E2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

559295:KLTH0D08184g
gene id: 559295:KLTH0D08184g
uniprot id: C5DGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

559295:KLTH0E06996g
gene id: 559295:KLTH0E06996g
uniprot id: C5DHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0A06732g
gene id: 559295:KLTH0A06732g
uniprot id: C5DC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

559295:KLTH0B09152g
gene id: 559295:KLTH0B09152g
uniprot id: C5DD85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

559295:KLTH0B07326g
gene id: 559295:KLTH0B07326g
uniprot id: C5DD07
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H01958g
gene id: 559295:KLTH0H01958g
uniprot id: C5E241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Regulates the cell cycle in a nutrient dependent manner.

559295:KLTH0B04488g
gene id: 559295:KLTH0B04488g
uniprot id: C5DCN3
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

559295:KLTH0D02948g
gene id: 559295:KLTH0D02948g
uniprot id: C5DG74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

559295:KLTH0E12034g
gene id: 559295:KLTH0E12034g
uniprot id: C5DIF2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

559295:KLTH0H13728g
gene id: 559295:KLTH0H13728g
uniprot id: C5E3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0F13882g
gene id: 559295:KLTH0F13882g
uniprot id: C5DJ65
names: Similarity
messages: Belongs to the MAPRE family.

559295:KLTH0D06358g
gene id: 559295:KLTH0D06358g
uniprot id: C5DGL7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

559295:KLTH0H11176g
gene id: 559295:KLTH0H11176g
uniprot id: C5E384
names: Similarity
messages: Belongs to the cullin family.

559295:KLTH0D12584g
gene id: 559295:KLTH0D12584g
uniprot id: C5DF65
names: Subunit
messages: Homodimer.

559295:KLTH0C00594g
gene id: 559295:KLTH0C00594g
uniprot id: C5DDF5
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

559295:KLTH0D13442g
gene id: 559295:KLTH0D13442g
uniprot id: C5DFA1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C00462g
gene id: 559295:KLTH0C00462g
uniprot id: C5DDE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0D07458g
gene id: 559295:KLTH0D07458g
uniprot id: C5DGR4
names: Similarity
messages: Belongs to the NifU family.

559295:KLTH0C10824g
gene id: 559295:KLTH0C10824g
uniprot id: C5DEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM34 family.
messages: Mitochondrion membrane

559295:KLTH0E01254g
gene id: 559295:KLTH0E01254g
uniprot id: C5DH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0C05764g
gene id: 559295:KLTH0C05764g
uniprot id: C5DE26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

559295:KLTH0D11066g
gene id: 559295:KLTH0D11066g
uniprot id: C5DEZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Required for methionine synthesis and maintenance of intact mitochondrial DNA. Involved in telomere maintenance.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

559295:KLTH0E00902g
gene id: 559295:KLTH0E00902g
uniprot id: C5DH29
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

559295:KLTH0A04466g
gene id: 559295:KLTH0A04466g
uniprot id: C5DBQ2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

559295:KLTH0H14850g
gene id: 559295:KLTH0H14850g
uniprot id: C5E3M7
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

559295:KLTH0F18194g
gene id: 559295:KLTH0F18194g
uniprot id: C5DJQ0
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

559295:KLTH0D17446g
gene id: 559295:KLTH0D17446g
uniprot id: C5DFS1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

559295:KLTH0D08778g
gene id: 559295:KLTH0D08778g
uniprot id: C5DGW3
names: Similarity
messages: Belongs to the CCS1 family.

559295:KLTH0D14190g
gene id: 559295:KLTH0D14190g
uniprot id: C5DFD3
names: Similarity
messages: Belongs to the VAC14 family.

559295:KLTH0G05456g
gene id: 559295:KLTH0G05456g
uniprot id: C5DM27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum

559295:KLTH0G08778g
gene id: 559295:KLTH0G08778g
uniprot id: C5DMG7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0C06578g
gene id: 559295:KLTH0C06578g
uniprot id: C5DE63
names: Similarity
messages: Belongs to the AAR2 family.

559295:KLTH0G04642g
gene id: 559295:KLTH0G04642g
uniprot id: C5DLZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

559295:KLTH0E07172g
gene id: 559295:KLTH0E07172g
uniprot id: C5DHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

559295:KLTH0G03828g
gene id: 559295:KLTH0G03828g
uniprot id: C5DLV4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

559295:KLTH0A07766g
gene id: 559295:KLTH0A07766g
uniprot id: C5DC48
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E14124g
gene id: 559295:KLTH0E14124g
uniprot id: C5DIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

559295:KLTH0D04510g
gene id: 559295:KLTH0D04510g
uniprot id: C5DGD8
names: Function
names: Similarity
messages: Belongs to the SPG4 family.
messages: Stationary phase-essential protein not required for growth on nonfermentable carbon sources.

559295:KLTH0A06512g
gene id: 559295:KLTH0A06512g
uniprot id: C5DBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

559295:KLTH0C03212g
gene id: 559295:KLTH0C03212g
uniprot id: C5DDR6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

559295:KLTH0H02816g
gene id: 559295:KLTH0H02816g
uniprot id: C5E280
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E13860g
gene id: 559295:KLTH0E13860g
uniprot id: C5DIN3
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

559295:KLTH0B08558g
gene id: 559295:KLTH0B08558g
uniprot id: C5DD61
names: Similarity
messages: Belongs to the FMO family.

559295:KLTH0H10736g
gene id: 559295:KLTH0H10736g
uniprot id: C5E365
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0G10384g
gene id: 559295:KLTH0G10384g
uniprot id: C5DMN7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

559295:KLTH0D08910g
gene id: 559295:KLTH0D08910g
uniprot id: C5DGW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

559295:KLTH0D04664g
gene id: 559295:KLTH0D04664g
uniprot id: C5DGE5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

559295:KLTH0F18986g
gene id: 559295:KLTH0F18986g
uniprot id: C5DJT5
names: Similarity
messages: Belongs to the KRI1 family.

559295:KLTH0H10010g
gene id: 559295:KLTH0H10010g
uniprot id: C5E336
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D16324g
gene id: 559295:KLTH0D16324g
uniprot id: C5DFM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

559295:KLTH0G13794g
gene id: 559295:KLTH0G13794g
uniprot id: C5DN34
names: Similarity
messages: Belongs to the FGGY kinase family.

559295:KLTH0H04290g
gene id: 559295:KLTH0H04290g
uniprot id: C5E2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

559295:KLTH0D10560g
gene id: 559295:KLTH0D10560g
uniprot id: C5DEX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

559295:KLTH0H14498g
gene id: 559295:KLTH0H14498g
uniprot id: C5E3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

559295:KLTH0A03938g
gene id: 559295:KLTH0A03938g
uniprot id: C5DBM8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

559295:KLTH0D04466g
gene id: 559295:KLTH0D04466g
uniprot id: C5DGD7
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

559295:KLTH0G12738g
gene id: 559295:KLTH0G12738g
uniprot id: C5DMY8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Nucleus

559295:KLTH0D02068g
gene id: 559295:KLTH0D02068g
uniprot id: C5DG34
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

559295:KLTH0D04730g
gene id: 559295:KLTH0D04730g
uniprot id: C5DGE8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

559295:KLTH0F11946g
gene id: 559295:KLTH0F11946g
uniprot id: C5DLC9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0G04334g
gene id: 559295:KLTH0G04334g
uniprot id: C5DLX7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B00396g
gene id: 559295:KLTH0B00396g
uniprot id: C5DC66
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H01694g
gene id: 559295:KLTH0H01694g
uniprot id: C5E229
names: Similarity
messages: Belongs to the cyclin family.

559295:KLTH0E12254g
gene id: 559295:KLTH0E12254g
uniprot id: C5DIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0E12430g
gene id: 559295:KLTH0E12430g
uniprot id: C5DIG9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

559295:KLTH0F08800g
gene id: 559295:KLTH0F08800g
uniprot id: C5DKZ8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B04972g
gene id: 559295:KLTH0B04972g
uniprot id: C5DCQ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0D02772g
gene id: 559295:KLTH0D02772g
uniprot id: C5DG66
names: Similarity
messages: Belongs to the OPI10 family.

559295:KLTH0G12496g
gene id: 559295:KLTH0G12496g
uniprot id: C5DMX8
names: Similarity
messages: Belongs to the dopey family.

559295:KLTH0F02266g
gene id: 559295:KLTH0F02266g
uniprot id: C5DK71
names: Similarity
messages: Belongs to the cyclin family.

559295:KLTH0E04400g
gene id: 559295:KLTH0E04400g
uniprot id: C5DHH6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G16786g
gene id: 559295:KLTH0G16786g
uniprot id: C5DNG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

559295:KLTH0H15532g
gene id: 559295:KLTH0H15532g
uniprot id: C5E3Q6
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

559295:KLTH0F01980g
gene id: 559295:KLTH0F01980g
uniprot id: C5DK58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0A03916g
gene id: 559295:KLTH0A03916g
uniprot id: C5DBM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

559295:KLTH0E13772g
gene id: 559295:KLTH0E13772g
uniprot id: C5DIM9
names: Subunit
messages: Homodimer.

559295:KLTH0D01386g
gene id: 559295:KLTH0D01386g
uniprot id: C5DG04
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

559295:KLTH0E15686g
gene id: 559295:KLTH0E15686g
uniprot id: C5DIW4
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

559295:KLTH0C03872g
gene id: 559295:KLTH0C03872g
uniprot id: C5DDU5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

559295:KLTH0F11220g
gene id: 559295:KLTH0F11220g
uniprot id: C5DL98
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

559295:KLTH0G09988g
gene id: 559295:KLTH0G09988g
uniprot id: C5DML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

559295:KLTH0F02640g
gene id: 559295:KLTH0F02640g
uniprot id: C5DK88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

559295:KLTH0G19448g
gene id: 559295:KLTH0G19448g
uniprot id: C5DNS5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E14256g
gene id: 559295:KLTH0E14256g
uniprot id: C5DIQ1
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D07260g
gene id: 559295:KLTH0D07260g
uniprot id: C5DGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDS1/RGT1 family.
messages: Cytoplasm
messages: Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose. In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator. In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription (By similarity).
messages: Nucleus

559295:KLTH0G04422g
gene id: 559295:KLTH0G04422g
uniprot id: C5DLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Nucleus

559295:KLTH0G14586g
gene id: 559295:KLTH0G14586g
uniprot id: C5DN68
names: Similarity
messages: Belongs to the SPT2 family.

559295:KLTH0H14806g
gene id: 559295:KLTH0H14806g
uniprot id: C5E3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

559295:KLTH0G07040g
gene id: 559295:KLTH0G07040g
uniprot id: C5DM96
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

559295:KLTH0E02178g
gene id: 559295:KLTH0E02178g
uniprot id: C5DH86
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0B03212g
gene id: 559295:KLTH0B03212g
uniprot id: C5DCH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

559295:KLTH0E12210g
gene id: 559295:KLTH0E12210g
uniprot id: C5DIF9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0H13574g
gene id: 559295:KLTH0H13574g
uniprot id: C5E3H3
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

559295:KLTH0D15950g
gene id: 559295:KLTH0D15950g
uniprot id: C5DFK8
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

559295:KLTH0D16016g
gene id: 559295:KLTH0D16016g
uniprot id: C5DFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Mediates the nuclear localization of the ribonucleotide reductase.
messages: Nucleus

559295:KLTH0H00594g
gene id: 559295:KLTH0H00594g
uniprot id: C5E1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0B06820g
gene id: 559295:KLTH0B06820g
uniprot id: C5DCY5
names: Similarity
messages: Belongs to the APC1 family.

559295:KLTH0C04158g
gene id: 559295:KLTH0C04158g
uniprot id: C5DDV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

559295:KLTH0E16478g
gene id: 559295:KLTH0E16478g
uniprot id: C5DIZ9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F00968g
gene id: 559295:KLTH0F00968g
uniprot id: C5DK13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

559295:KLTH0G01518g
gene id: 559295:KLTH0G01518g
uniprot id: C5DLK9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

559295:KLTH0F10846g
gene id: 559295:KLTH0F10846g
uniprot id: C5DL85
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

559295:KLTH0D12474g
gene id: 559295:KLTH0D12474g
uniprot id: C5DF60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA.
messages: Belongs to the CAF20 family.
messages: Cytoplasm

559295:KLTH0G14784g
gene id: 559295:KLTH0G14784g
uniprot id: C5DN77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

559295:KLTH0H08844g
gene id: 559295:KLTH0H08844g
uniprot id: C5E2Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G07744g
gene id: 559295:KLTH0G07744g
uniprot id: C5DMC5
names: Similarity
messages: Belongs to the cyclin family.

559295:KLTH0F05874g
gene id: 559295:KLTH0F05874g
uniprot id: C5DKM3
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

559295:KLTH0G15994g
gene id: 559295:KLTH0G15994g
uniprot id: C5DND1
names: Similarity
messages: Belongs to the BRX1 family.

559295:KLTH0C03190g
gene id: 559295:KLTH0C03190g
uniprot id: C5DDR5
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F09328g
gene id: 559295:KLTH0F09328g
uniprot id: C5DL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

559295:KLTH0H03520g
gene id: 559295:KLTH0H03520g
uniprot id: C5E2B1
names: Similarity
messages: Belongs to the SELO family.

559295:KLTH0C06798g
gene id: 559295:KLTH0C06798g
uniprot id: C5DE71
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

559295:KLTH0G18744g
gene id: 559295:KLTH0G18744g
uniprot id: C5DNP3
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

559295:KLTH0G13090g
gene id: 559295:KLTH0G13090g
uniprot id: C5DN02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

559295:KLTH0H09504g
gene id: 559295:KLTH0H09504g
uniprot id: C5E315
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0E00198g
gene id: 559295:KLTH0E00198g
uniprot id: C5DH00
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

559295:KLTH0D13200g
gene id: 559295:KLTH0D13200g
uniprot id: C5DF91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

559295:KLTH0H02860g
gene id: 559295:KLTH0H02860g
uniprot id: C5E282
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F13992g
gene id: 559295:KLTH0F13992g
uniprot id: C5DJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAM1 family.
messages: Nucleus
messages: kinetochore

559295:KLTH0G11022g
gene id: 559295:KLTH0G11022g
uniprot id: C5DMR4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

559295:KLTH0D16632g
gene id: 559295:KLTH0D16632g
uniprot id: C5DFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

559295:KLTH0H01804g
gene id: 559295:KLTH0H01804g
uniprot id: C5E234
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

559295:KLTH0G17270g
gene id: 559295:KLTH0G17270g
uniprot id: C5DNI2
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

559295:KLTH0G13772g
gene id: 559295:KLTH0G13772g
uniprot id: C5DN33
names: Function
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

559295:KLTH0E11198g
gene id: 559295:KLTH0E11198g
uniprot id: C5DIB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

559295:KLTH0H09064g
gene id: 559295:KLTH0H09064g
uniprot id: C5E2Z5
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

559295:KLTH0G07216g
gene id: 559295:KLTH0G07216g
uniprot id: C5DMA4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0A05654g
gene id: 559295:KLTH0A05654g
uniprot id: C5DBV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.

559295:KLTH0H10186g
gene id: 559295:KLTH0H10186g
uniprot id: C5E341
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

559295:KLTH0F19888g
gene id: 559295:KLTH0F19888g
uniprot id: C5DJX6
names: Subcellular Location Annotation
messages: Membrane
messages: cell wall

559295:KLTH0B04114g
gene id: 559295:KLTH0B04114g
uniprot id: C5DCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

559295:KLTH0D17490g
gene id: 559295:KLTH0D17490g
uniprot id: C5DFS3
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

559295:KLTH0B01100g
gene id: 559295:KLTH0B01100g
uniprot id: C5DC90
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D04686g
gene id: 559295:KLTH0D04686g
uniprot id: C5DGE6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

559295:KLTH0C11462g
gene id: 559295:KLTH0C11462g
uniprot id: C5DER4
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

559295:KLTH0H04532g
gene id: 559295:KLTH0H04532g
uniprot id: C5E2F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

559295:KLTH0E15356g
gene id: 559295:KLTH0E15356g
uniprot id: C5DIU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

559295:KLTH0A03036g
gene id: 559295:KLTH0A03036g
uniprot id: C5DBJ0
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G01012g
gene id: 559295:KLTH0G01012g
uniprot id: C5DLI6
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

559295:KLTH0F10032g
gene id: 559295:KLTH0F10032g
uniprot id: C5DL52
names: Similarity
messages: Belongs to the ATG16 family.

559295:KLTH0A05676g
gene id: 559295:KLTH0A05676g
uniprot id: C5DBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS27 family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
messages: Endosome membrane
messages: Membrane

559295:KLTH0H08976g
gene id: 559295:KLTH0H08976g
uniprot id: C5E2Z1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0G12936g
gene id: 559295:KLTH0G12936g
uniprot id: C5DMZ5
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

559295:KLTH0E12100g
gene id: 559295:KLTH0E12100g
uniprot id: C5DIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

559295:KLTH0D13376g
gene id: 559295:KLTH0D13376g
uniprot id: C5DF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

559295:KLTH0F00550g
gene id: 559295:KLTH0F00550g
uniprot id: C5DJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G14718g
gene id: 559295:KLTH0G14718g
uniprot id: C5DN74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

559295:KLTH0H13156g
gene id: 559295:KLTH0H13156g
uniprot id: C5E3G1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

559295:KLTH0E16610g
gene id: 559295:KLTH0E16610g
uniprot id: C5DJ05
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

559295:KLTH0D11682g
gene id: 559295:KLTH0D11682g
uniprot id: C5DF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

559295:KLTH0E02002g
gene id: 559295:KLTH0E02002g
uniprot id: C5DH78
names: Similarity
messages: Belongs to the phospholipid scramblase family.

559295:KLTH0E01958g
gene id: 559295:KLTH0E01958g
uniprot id: C5DH76
names: Similarity
messages: Belongs to the VPS25 family.

559295:KLTH0F16588g
gene id: 559295:KLTH0F16588g
uniprot id: C5DJI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPT35 family.
messages: Endosome membrane
messages: Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
messages: Vacuole membrane

559295:KLTH0D05632g
gene id: 559295:KLTH0D05632g
uniprot id: C5DGI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

559295:KLTH0B00484g
gene id: 559295:KLTH0B00484g
uniprot id: C5DC70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0C05192g
gene id: 559295:KLTH0C05192g
uniprot id: C5DE02
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

559295:KLTH0E06358g
gene id: 559295:KLTH0E06358g
uniprot id: C5DHQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

559295:KLTH0B04818g
gene id: 559295:KLTH0B04818g
uniprot id: C5DCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

559295:KLTH0H12166g
gene id: 559295:KLTH0H12166g
uniprot id: C5E3C3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

559295:KLTH0C05434g
gene id: 559295:KLTH0C05434g
uniprot id: C5DE12
names: Similarity
messages: Belongs to the MIX23 family.

559295:KLTH0B08712g
gene id: 559295:KLTH0B08712g
uniprot id: C5DD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0G18480g
gene id: 559295:KLTH0G18480g
uniprot id: C5DNN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

559295:KLTH0D16038g
gene id: 559295:KLTH0D16038g
uniprot id: C5DFL2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0B08514g
gene id: 559295:KLTH0B08514g
uniprot id: C5DD59
names: Similarity
messages: Belongs to the enolase family.

559295:KLTH0F00176g
gene id: 559295:KLTH0F00176g
uniprot id: C5DJY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VEL1 family.
messages: cytosol

559295:KLTH0A04224g
gene id: 559295:KLTH0A04224g
uniprot id: C5DBP1
names: Similarity
messages: Belongs to the RutC family.

559295:KLTH0D14256g
gene id: 559295:KLTH0D14256g
uniprot id: C5DFD6
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

559295:KLTH0E10802g
gene id: 559295:KLTH0E10802g
uniprot id: C5DI98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

559295:KLTH0E14366g
gene id: 559295:KLTH0E14366g
uniprot id: C5DIQ5
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

559295:KLTH0G18810g
gene id: 559295:KLTH0G18810g
uniprot id: C5DNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0B06974g
gene id: 559295:KLTH0B06974g
uniprot id: C5DCZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

559295:KLTH0E15092g
gene id: 559295:KLTH0E15092g
uniprot id: C5DIT7
names: Similarity
messages: Belongs to the FES1 family.

559295:KLTH0F02486g
gene id: 559295:KLTH0F02486g
uniprot id: C5DK81
names: Similarity
messages: Belongs to the IST1 family.

559295:KLTH0H01738g
gene id: 559295:KLTH0H01738g
uniprot id: C5E231
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G18766g
gene id: 559295:KLTH0G18766g
uniprot id: C5DNP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

559295:KLTH0E05236g
gene id: 559295:KLTH0E05236g
uniprot id: C5DHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

559295:KLTH0H15972g
gene id: 559295:KLTH0H15972g
uniprot id: C5E3S6
names: Subcellular Location Annotation
messages: nuclear pore complex

559295:KLTH0C08536g
gene id: 559295:KLTH0C08536g
uniprot id: C5DEE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

559295:KLTH0E08030g
gene id: 559295:KLTH0E08030g
uniprot id: C5DHX9
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

559295:KLTH0G07260g
gene id: 559295:KLTH0G07260g
uniprot id: C5DMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0H15598g
gene id: 559295:KLTH0H15598g
uniprot id: C5E3Q9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

559295:KLTH0F19668g
gene id: 559295:KLTH0F19668g
uniprot id: C5DJW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

559295:KLTH0H15158g
gene id: 559295:KLTH0H15158g
uniprot id: C5E3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

559295:KLTH0G07018g
gene id: 559295:KLTH0G07018g
uniprot id: C5DM95
names: Similarity
messages: Belongs to the peptidase S9B family.

559295:KLTH0E00330g
gene id: 559295:KLTH0E00330g
uniprot id: C5DH06
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

559295:KLTH0G11088g
gene id: 559295:KLTH0G11088g
uniprot id: C5DMR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

559295:KLTH0G02640g
gene id: 559295:KLTH0G02640g
uniprot id: C5DLQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.

559295:KLTH0F11484g
gene id: 559295:KLTH0F11484g
uniprot id: C5DLA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG14 family.
messages: Vacuole membrane

559295:KLTH0G16852g
gene id: 559295:KLTH0G16852g
uniprot id: C5DNG7
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G16764g
gene id: 559295:KLTH0G16764g
uniprot id: C5DNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

559295:KLTH0D08008g
gene id: 559295:KLTH0D08008g
uniprot id: C5DGT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

559295:KLTH0F10626g
gene id: 559295:KLTH0F10626g
uniprot id: C5DL75
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

559295:KLTH0D14850g
gene id: 559295:KLTH0D14850g
uniprot id: C5DFG2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

559295:KLTH0G13486g
gene id: 559295:KLTH0G13486g
uniprot id: C5DN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

559295:KLTH0D03630g
gene id: 559295:KLTH0D03630g
uniprot id: C5DGA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

559295:KLTH0F07590g
gene id: 559295:KLTH0F07590g
uniprot id: C5DKU4
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

559295:KLTH0B00462g
gene id: 559295:KLTH0B00462g
uniprot id: C5DC69
names: Similarity
messages: Belongs to the FMO family.

559295:KLTH0C02112g
gene id: 559295:KLTH0C02112g
uniprot id: C5DDM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

559295:KLTH0G05060g
gene id: 559295:KLTH0G05060g
uniprot id: C5DM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

559295:KLTH0G12980g
gene id: 559295:KLTH0G12980g
uniprot id: C5DMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

559295:KLTH0E00528g
gene id: 559295:KLTH0E00528g
uniprot id: C5DH13
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A05060g
gene id: 559295:KLTH0A05060g
uniprot id: C5DBS8
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

559295:KLTH0C11352g
gene id: 559295:KLTH0C11352g
uniprot id: C5DER0
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0B09878g
gene id: 559295:KLTH0B09878g
uniprot id: C5DDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

559295:KLTH0G04444g
gene id: 559295:KLTH0G04444g
uniprot id: C5DLY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

559295:KLTH0E05764g
gene id: 559295:KLTH0E05764g
uniprot id: C5DHN4
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

559295:KLTH0F19118g
gene id: 559295:KLTH0F19118g
uniprot id: C5DJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

559295:KLTH0F16566g
gene id: 559295:KLTH0F16566g
uniprot id: C5DJH9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

559295:KLTH0H00418g
gene id: 559295:KLTH0H00418g
uniprot id: C5E1X5
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

559295:KLTH0C02706g
gene id: 559295:KLTH0C02706g
uniprot id: C5DDP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

559295:KLTH0F16830g
gene id: 559295:KLTH0F16830g
uniprot id: C5DJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

559295:KLTH0B02816g
gene id: 559295:KLTH0B02816g
uniprot id: C5DCG3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E06842g
gene id: 559295:KLTH0E06842g
uniprot id: C5DHS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

559295:KLTH0C06248g
gene id: 559295:KLTH0C06248g
uniprot id: C5DE48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

559295:KLTH0E03476g
gene id: 559295:KLTH0E03476g
uniprot id: C5DHD5
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G11396g
gene id: 559295:KLTH0G11396g
uniprot id: C5DMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

559295:KLTH0G15686g
gene id: 559295:KLTH0G15686g
uniprot id: C5DNB7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0F06534g
gene id: 559295:KLTH0F06534g
uniprot id: C5DKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

559295:KLTH0C00748g
gene id: 559295:KLTH0C00748g
uniprot id: C5DDG2
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E14762g
gene id: 559295:KLTH0E14762g
uniprot id: C5DIS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

559295:KLTH0B01738g
gene id: 559295:KLTH0B01738g
uniprot id: C5DCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

559295:KLTH0B08976g
gene id: 559295:KLTH0B08976g
uniprot id: C5DD77
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0H04730g
gene id: 559295:KLTH0H04730g
uniprot id: C5E2G3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G14058g
gene id: 559295:KLTH0G14058g
uniprot id: C5DN45
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

559295:KLTH0E04708g
gene id: 559295:KLTH0E04708g
uniprot id: C5DHJ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

559295:KLTH0A00726g
gene id: 559295:KLTH0A00726g
uniprot id: C5DB95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

559295:KLTH0A05698g
gene id: 559295:KLTH0A05698g
uniprot id: C5DBV7
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F09636g
gene id: 559295:KLTH0F09636g
uniprot id: C5DL35
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0B10098g
gene id: 559295:KLTH0B10098g
uniprot id: C5DDC5
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

559295:KLTH0H03850g
gene id: 559295:KLTH0H03850g
uniprot id: C5E2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

559295:KLTH0E02772g
gene id: 559295:KLTH0E02772g
uniprot id: C5DHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0F09966g
gene id: 559295:KLTH0F09966g
uniprot id: C5DL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

559295:KLTH0F11880g
gene id: 559295:KLTH0F11880g
uniprot id: C5DLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0E05896g
gene id: 559295:KLTH0E05896g
uniprot id: C5DHP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

559295:KLTH0H01254g
gene id: 559295:KLTH0H01254g
uniprot id: C5E209
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

559295:KLTH0B01958g
gene id: 559295:KLTH0B01958g
uniprot id: C5DCC7
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

559295:KLTH0E07568g
gene id: 559295:KLTH0E07568g
uniprot id: C5DHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

559295:KLTH0H13134g
gene id: 559295:KLTH0H13134g
uniprot id: C5E3G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus

559295:KLTH0F02068g
gene id: 559295:KLTH0F02068g
uniprot id: C5DK62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

559295:KLTH0H12188g
gene id: 559295:KLTH0H12188g
uniprot id: C5E3C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

559295:KLTH0C00286g
gene id: 559295:KLTH0C00286g
uniprot id: C5DDE2
names: Similarity
messages: Belongs to the PhyH family.

559295:KLTH0B02926g
gene id: 559295:KLTH0B02926g
uniprot id: C5DCG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

559295:KLTH0B06358g
gene id: 559295:KLTH0B06358g
uniprot id: C5DCW6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F08580g
gene id: 559295:KLTH0F08580g
uniprot id: C5DKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

559295:KLTH0E11022g
gene id: 559295:KLTH0E11022g
uniprot id: C5DIA7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

559295:KLTH0E07832g
gene id: 559295:KLTH0E07832g
uniprot id: C5DHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

559295:KLTH0F07612g
gene id: 559295:KLTH0F07612g
uniprot id: C5DKU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

559295:KLTH0F01936g
gene id: 559295:KLTH0F01936g
uniprot id: C5DK56
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H05434g
gene id: 559295:KLTH0H05434g
uniprot id: C5E2J2
names: Similarity
messages: Belongs to the bystin family.

559295:KLTH0A01914g
gene id: 559295:KLTH0A01914g
uniprot id: C5DBE4
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G11220g
gene id: 559295:KLTH0G11220g
uniprot id: C5DMS3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E15950g
gene id: 559295:KLTH0E15950g
uniprot id: C5DIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

559295:KLTH0B01034g
gene id: 559295:KLTH0B01034g
uniprot id: C5DC87
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

559295:KLTH0F18678g
gene id: 559295:KLTH0F18678g
uniprot id: C5DJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F10714g
gene id: 559295:KLTH0F10714g
uniprot id: C5DL79
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

559295:KLTH0G07480g
gene id: 559295:KLTH0G07480g
uniprot id: C5DMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

559295:KLTH0D15796g
gene id: 559295:KLTH0D15796g
uniprot id: C5DFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0D12210g
gene id: 559295:KLTH0D12210g
uniprot id: C5DF49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

559295:KLTH0F14080g
gene id: 559295:KLTH0F14080g
uniprot id: C5DJ74
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E14674g
gene id: 559295:KLTH0E14674g
uniprot id: C5DIR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

559295:KLTH0C00792g
gene id: 559295:KLTH0C00792g
uniprot id: C5DDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

559295:KLTH0H05500g
gene id: 559295:KLTH0H05500g
uniprot id: C5E2J5
names: Similarity
messages: Belongs to the peptidase M20A family.

559295:KLTH0A02178g
gene id: 559295:KLTH0A02178g
uniprot id: C5DBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0F08844g
gene id: 559295:KLTH0F08844g
uniprot id: C5DL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

559295:KLTH0D11792g
gene id: 559295:KLTH0D11792g
uniprot id: C5DF30
names: Similarity
messages: Belongs to the NXF family.

559295:KLTH0B01232g
gene id: 559295:KLTH0B01232g
uniprot id: C5DC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: Belongs to the TOG/XMAP215 family.
messages: spindle

559295:KLTH0B09328g
gene id: 559295:KLTH0B09328g
uniprot id: C5DD93
names: Similarity
messages: Belongs to the peptidase S10 family.

559295:KLTH0C06732g
gene id: 559295:KLTH0C06732g
uniprot id: C5DE69
names: Similarity
messages: Belongs to the peptidase C19 family.

559295:KLTH0F03784g
gene id: 559295:KLTH0F03784g
uniprot id: C5DKD6
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

559295:KLTH0H08712g
gene id: 559295:KLTH0H08712g
uniprot id: C5E2Y0
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F14234g
gene id: 559295:KLTH0F14234g
uniprot id: C5DJ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

559295:KLTH0B02134g
gene id: 559295:KLTH0B02134g
uniprot id: C5DCD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

559295:KLTH0B02618g
gene id: 559295:KLTH0B02618g
uniprot id: C5DCF4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

559295:KLTH0B04620g
gene id: 559295:KLTH0B04620g
uniprot id: C5DCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AEP1 family.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.

559295:KLTH0D06600g
gene id: 559295:KLTH0D06600g
uniprot id: C5DGM8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F03212g
gene id: 559295:KLTH0F03212g
uniprot id: C5DKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

559295:KLTH0E03938g
gene id: 559295:KLTH0E03938g
uniprot id: C5DHF5
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0E02200g
gene id: 559295:KLTH0E02200g
uniprot id: C5DH87
names: Similarity
messages: Belongs to the ClpA/ClpB family.

559295:KLTH0G04180g
gene id: 559295:KLTH0G04180g
uniprot id: C5DLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0B00418g
gene id: 559295:KLTH0B00418g
uniprot id: C5DC67
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

559295:KLTH0E08756g
gene id: 559295:KLTH0E08756g
uniprot id: C5DI09
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

559295:KLTH0B01848g
gene id: 559295:KLTH0B01848g
uniprot id: C5DCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0H06204g
gene id: 559295:KLTH0H06204g
uniprot id: C5E2M6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

559295:KLTH0H14630g
gene id: 559295:KLTH0H14630g
uniprot id: C5E3L8
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

559295:KLTH0C05082g
gene id: 559295:KLTH0C05082g
uniprot id: C5DDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
messages: Membrane
messages: Nucleus membrane

559295:KLTH0C06226g
gene id: 559295:KLTH0C06226g
uniprot id: C5DE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

559295:KLTH0H01760g
gene id: 559295:KLTH0H01760g
uniprot id: C5E232
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

559295:KLTH0D05060g
gene id: 559295:KLTH0D05060g
uniprot id: C5DGG1
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

559295:KLTH0E14058g
gene id: 559295:KLTH0E14058g
uniprot id: C5DIP2
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.

559295:KLTH0D03828g
gene id: 559295:KLTH0D03828g
uniprot id: C5DGB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

559295:KLTH0E13200g
gene id: 559295:KLTH0E13200g
uniprot id: C5DIK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

559295:KLTH0C10340g
gene id: 559295:KLTH0C10340g
uniprot id: C5DEM0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0H03652g
gene id: 559295:KLTH0H03652g
uniprot id: C5E2B7
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

559295:KLTH0D10824g
gene id: 559295:KLTH0D10824g
uniprot id: C5DEY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

559295:KLTH0B00924g
gene id: 559295:KLTH0B00924g
uniprot id: C5DC83
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0D11374g
gene id: 559295:KLTH0D11374g
uniprot id: C5DF11
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

559295:KLTH0E08624g
gene id: 559295:KLTH0E08624g
uniprot id: C5DI03
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

559295:KLTH0F03586g
gene id: 559295:KLTH0F03586g
uniprot id: C5DKC8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

559295:KLTH0F04246g
gene id: 559295:KLTH0F04246g
uniprot id: C5DKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

559295:KLTH0G08074g
gene id: 559295:KLTH0G08074g
uniprot id: C5DME0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

559295:KLTH0G01188g
gene id: 559295:KLTH0G01188g
uniprot id: C5DLJ4
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

559295:KLTH0B10384g
gene id: 559295:KLTH0B10384g
uniprot id: C5DDD5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E11000g
gene id: 559295:KLTH0E11000g
uniprot id: C5DIA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

559295:KLTH0F13134g
gene id: 559295:KLTH0F13134g
uniprot id: C5DJ34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

559295:KLTH0E10604g
gene id: 559295:KLTH0E10604g
uniprot id: C5DI89
names: Similarity
messages: Belongs to the HMBS family.

559295:KLTH0B02508g
gene id: 559295:KLTH0B02508g
uniprot id: C5DCF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

559295:KLTH0F11374g
gene id: 559295:KLTH0F11374g
uniprot id: C5DLA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

559295:KLTH0H08646g
gene id: 559295:KLTH0H08646g
uniprot id: C5E2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: nucleolus

559295:KLTH0C06930g
gene id: 559295:KLTH0C06930g
uniprot id: C5DE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

559295:KLTH0G10846g
gene id: 559295:KLTH0G10846g
uniprot id: C5DMQ7
names: Similarity
messages: Belongs to the PPC synthetase family.

559295:KLTH0F02398g
gene id: 559295:KLTH0F02398g
uniprot id: C5DK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

559295:KLTH0H16038g
gene id: 559295:KLTH0H16038g
uniprot id: C5E3S9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H01584g
gene id: 559295:KLTH0H01584g
uniprot id: C5E224
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0D03388g
gene id: 559295:KLTH0D03388g
uniprot id: C5DG92
names: Similarity
messages: Belongs to the SAPS family.

559295:KLTH0F15422g
gene id: 559295:KLTH0F15422g
uniprot id: C5DJC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0F16126g
gene id: 559295:KLTH0F16126g
uniprot id: C5DJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC5 family.
messages: Cytoplasm
messages: May be involved in a process influencing telomere capping.

559295:KLTH0G18524g
gene id: 559295:KLTH0G18524g
uniprot id: C5DNN3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0G00440g
gene id: 559295:KLTH0G00440g
uniprot id: C5DLG0
names: Similarity
messages: Belongs to the hexokinase family.

559295:KLTH0C01562g
gene id: 559295:KLTH0C01562g
uniprot id: C5DDJ8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

559295:KLTH0F17226g
gene id: 559295:KLTH0F17226g
uniprot id: C5DJK7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

559295:KLTH0G12320g
gene id: 559295:KLTH0G12320g
uniprot id: C5DMX0
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

559295:KLTH0G18172g
gene id: 559295:KLTH0G18172g
uniprot id: C5DNL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG33 family.
messages: Involved in the selective degradation of mitochondria via autophagy during starvation and at post-log phase.
messages: Mitochondrion membrane

559295:KLTH0D04356g
gene id: 559295:KLTH0D04356g
uniprot id: C5DGD2
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0A03520g
gene id: 559295:KLTH0A03520g
uniprot id: C5DBL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

559295:KLTH0B10032g
gene id: 559295:KLTH0B10032g
uniprot id: C5DDC2
names: Similarity
messages: Belongs to the oxoprolinase family.

559295:KLTH0F03036g
gene id: 559295:KLTH0F03036g
uniprot id: C5DKA5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F04510g
gene id: 559295:KLTH0F04510g
uniprot id: C5DKG6
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

559295:KLTH0B01298g
gene id: 559295:KLTH0B01298g
uniprot id: C5DC98
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

559295:KLTH0C11902g
gene id: 559295:KLTH0C11902g
uniprot id: C5DET0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

559295:KLTH0H07854g
gene id: 559295:KLTH0H07854g
uniprot id: C5E2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG1 family.
messages: Essential for respiratory growth and required for mitochondrial protein synthesis. Required for vacuolar acidification (By similarity).
messages: Mitochondrion

559295:KLTH0E16566g
gene id: 559295:KLTH0E16566g
uniprot id: C5DJ03
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

559295:KLTH0B03322g
gene id: 559295:KLTH0B03322g
uniprot id: C5DCI4
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

559295:KLTH0A02904g
gene id: 559295:KLTH0A02904g
uniprot id: C5DBI5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0D11572g
gene id: 559295:KLTH0D11572g
uniprot id: C5DF20
names: Similarity
messages: Belongs to the APC5 family.

559295:KLTH0G18568g
gene id: 559295:KLTH0G18568g
uniprot id: C5DNN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

559295:KLTH0B01584g
gene id: 559295:KLTH0B01584g
uniprot id: C5DCB0
names: Similarity
messages: Belongs to the cytidylyltransferase family.

559295:KLTH0D18194g
gene id: 559295:KLTH0D18194g
uniprot id: C5DFV2
names: Subcellular Location Annotation
messages: Cell surface

559295:KLTH0H04400g
gene id: 559295:KLTH0H04400g
uniprot id: C5E2F0
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

559295:KLTH0D16214g
gene id: 559295:KLTH0D16214g
uniprot id: C5DFM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

559295:KLTH0G08976g
gene id: 559295:KLTH0G08976g
uniprot id: C5DMH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

559295:KLTH0G11528g
gene id: 559295:KLTH0G11528g
uniprot id: C5DMT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

559295:KLTH0G19074g
gene id: 559295:KLTH0G19074g
uniprot id: C5DNQ8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

559295:KLTH0B06226g
gene id: 559295:KLTH0B06226g
uniprot id: C5DCW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0C03322g
gene id: 559295:KLTH0C03322g
uniprot id: C5DDS1
names: Similarity
messages: Belongs to the NAD kinase family.

559295:KLTH0A01870g
gene id: 559295:KLTH0A01870g
uniprot id: C5DBE2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H00858g
gene id: 559295:KLTH0H00858g
uniprot id: C5E1Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0A00484g
gene id: 559295:KLTH0A00484g
uniprot id: C5DB84
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H02464g
gene id: 559295:KLTH0H02464g
uniprot id: C5E264
names: Similarity
messages: Belongs to the cullin family.

559295:KLTH0E14036g
gene id: 559295:KLTH0E14036g
uniprot id: C5DIP1
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H06622g
gene id: 559295:KLTH0H06622g
uniprot id: C5E2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

559295:KLTH0F05808g
gene id: 559295:KLTH0F05808g
uniprot id: C5DKM0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H05148g
gene id: 559295:KLTH0H05148g
uniprot id: C5E2I2
names: Similarity
messages: Belongs to the PPP phosphatase family.

559295:KLTH0F00396g
gene id: 559295:KLTH0F00396g
uniprot id: C5DJY8
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E14476g
gene id: 559295:KLTH0E14476g
uniprot id: C5DIR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

559295:KLTH0G00704g
gene id: 559295:KLTH0G00704g
uniprot id: C5DLH2
names: Similarity
messages: Belongs to the RMD1/sif2 family.

559295:KLTH0D09878g
gene id: 559295:KLTH0D09878g
uniprot id: C5DEU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

559295:KLTH0G11726g
gene id: 559295:KLTH0G11726g
uniprot id: C5DMU6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G08580g
gene id: 559295:KLTH0G08580g
uniprot id: C5DMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G18656g
gene id: 559295:KLTH0G18656g
uniprot id: C5DNN9
names: Similarity
messages: Belongs to the TMCO4 family.

559295:KLTH0D04994g
gene id: 559295:KLTH0D04994g
uniprot id: C5DGF9
names: Similarity
messages: Belongs to the SSH4 family.

559295:KLTH0F11550g
gene id: 559295:KLTH0F11550g
uniprot id: C5DLB2
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

559295:KLTH0G12760g
gene id: 559295:KLTH0G12760g
uniprot id: C5DMY9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H06468g
gene id: 559295:KLTH0H06468g
uniprot id: C5E2N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

559295:KLTH0G04620g
gene id: 559295:KLTH0G04620g
uniprot id: C5DLZ0
names: Similarity
messages: Belongs to the UTP6 family.

559295:KLTH0C02882g
gene id: 559295:KLTH0C02882g
uniprot id: C5DDQ4
names: Similarity
messages: Belongs to the AIM32 family.

559295:KLTH0A05368g
gene id: 559295:KLTH0A05368g
uniprot id: C5DBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

559295:KLTH0E16500g
gene id: 559295:KLTH0E16500g
uniprot id: C5DJ00
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D09900g
gene id: 559295:KLTH0D09900g
uniprot id: C5DEU7
names: Similarity
messages: Belongs to the beclin family.

559295:KLTH0H07502g
gene id: 559295:KLTH0H07502g
uniprot id: C5E2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

559295:KLTH0C07370g
gene id: 559295:KLTH0C07370g
uniprot id: C5DE97
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

559295:KLTH0G10428g
gene id: 559295:KLTH0G10428g
uniprot id: C5DMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.

559295:KLTH0D02178g
gene id: 559295:KLTH0D02178g
uniprot id: C5DG39
names: Similarity
messages: Belongs to the MAK16 family.

559295:KLTH0G01606g
gene id: 559295:KLTH0G01606g
uniprot id: C5DLL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

559295:KLTH0F10560g
gene id: 559295:KLTH0F10560g
uniprot id: C5DL72
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

559295:KLTH0G06556g
gene id: 559295:KLTH0G06556g
uniprot id: C5DM74
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

559295:KLTH0E13398g
gene id: 559295:KLTH0E13398g
uniprot id: C5DIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the INA17 family.
messages: Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.
messages: Component of the inner membrane assembly (INA) complex, composed of INA17 and INA22. Interacts with a subset of F(1)F(0)-ATP synthase subunits of the F(1)-domain and the peripheral stalk.
messages: Mitochondrion inner membrane

559295:KLTH0F06094g
gene id: 559295:KLTH0F06094g
uniprot id: C5DKN3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

559295:KLTH0D00594g
gene id: 559295:KLTH0D00594g
uniprot id: C5DFW9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0C05478g
gene id: 559295:KLTH0C05478g
uniprot id: C5DE14
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

559295:KLTH0B05214g
gene id: 559295:KLTH0B05214g
uniprot id: C5DCR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

559295:KLTH0E04312g
gene id: 559295:KLTH0E04312g
uniprot id: C5DHH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

559295:KLTH0F05214g
gene id: 559295:KLTH0F05214g
uniprot id: C5DKJ5
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

559295:KLTH0D06116g
gene id: 559295:KLTH0D06116g
uniprot id: C5DGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

559295:KLTH0A02442g
gene id: 559295:KLTH0A02442g
uniprot id: C5DBG6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

559295:KLTH0A06754g
gene id: 559295:KLTH0A06754g
uniprot id: C5DC02
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0F14784g
gene id: 559295:KLTH0F14784g
uniprot id: C5DJA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

559295:KLTH0H12122g
gene id: 559295:KLTH0H12122g
uniprot id: C5E3C1
names: Similarity
messages: Belongs to the WD repeat LST8 family.

559295:KLTH0G15070g
gene id: 559295:KLTH0G15070g
uniprot id: C5DN90
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

559295:KLTH0E14784g
gene id: 559295:KLTH0E14784g
uniprot id: C5DIS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

559295:KLTH0D17512g
gene id: 559295:KLTH0D17512g
uniprot id: C5DFS4
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

559295:KLTH0C00946g
gene id: 559295:KLTH0C00946g
uniprot id: C5DDH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).
messages: Endoplasmic reticulum membrane
messages: The C-terminal short (CTS) helix is essential for catalytic activity. It may be accommodated as a transmembrane helix in the thinned membrane environment of the complex, similarly to the signal peptide in the complex substrates.

559295:KLTH0C08074g
gene id: 559295:KLTH0C08074g
uniprot id: C5DEC5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G04774g
gene id: 559295:KLTH0G04774g
uniprot id: C5DLZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
messages: Mitochondrion membrane

559295:KLTH0A06094g
gene id: 559295:KLTH0A06094g
uniprot id: C5DBX5
names: Similarity
messages: Belongs to the peptidase S8 family.

559295:KLTH0B10450g
gene id: 559295:KLTH0B10450g
uniprot id: C5DDD7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

559295:KLTH0G07326g
gene id: 559295:KLTH0G07326g
uniprot id: C5DMA8
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

559295:KLTH0F02662g
gene id: 559295:KLTH0F02662g
uniprot id: C5DK89
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D07854g
gene id: 559295:KLTH0D07854g
uniprot id: C5DGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC42 family.
messages: Forms a polymeric layer at the periphery of the spindle pole body (SPB) central plaque which has an essential function during SPB duplication and may facilitate attachment of the SPB to the nuclear membrane.
messages: Nucleus
messages: spindle pole body

559295:KLTH0G15510g
gene id: 559295:KLTH0G15510g
uniprot id: C5DNA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0C10670g
gene id: 559295:KLTH0C10670g
uniprot id: C5DEN4
names: Similarity
messages: Belongs to the lysophospholipase family.

559295:KLTH0B01320g
gene id: 559295:KLTH0B01320g
uniprot id: C5DC99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

559295:KLTH0F01034g
gene id: 559295:KLTH0F01034g
uniprot id: C5DK16
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.

559295:KLTH0D02816g
gene id: 559295:KLTH0D02816g
uniprot id: C5DG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

559295:KLTH0E13134g
gene id: 559295:KLTH0E13134g
uniprot id: C5DIK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0D16698g
gene id: 559295:KLTH0D16698g
uniprot id: C5DFP1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

559295:KLTH0E04774g
gene id: 559295:KLTH0E04774g
uniprot id: C5DHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

559295:KLTH0H01320g
gene id: 559295:KLTH0H01320g
uniprot id: C5E212
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

559295:KLTH0E06600g
gene id: 559295:KLTH0E06600g
uniprot id: C5DHR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

559295:KLTH0F09130g
gene id: 559295:KLTH0F09130g
uniprot id: C5DL13
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

559295:KLTH0F18326g
gene id: 559295:KLTH0F18326g
uniprot id: C5DJQ6
names: Similarity
messages: Belongs to the GcvT family. CAF17 subfamily.

559295:KLTH0E03960g
gene id: 559295:KLTH0E03960g
uniprot id: C5DHF6
names: Similarity
messages: Belongs to the PP2C family.

559295:KLTH0D12804g
gene id: 559295:KLTH0D12804g
uniprot id: C5DF75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

559295:KLTH0G18986g
gene id: 559295:KLTH0G18986g
uniprot id: C5DNQ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0G18832g
gene id: 559295:KLTH0G18832g
uniprot id: C5DNP7
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

559295:KLTH0G10758g
gene id: 559295:KLTH0G10758g
uniprot id: C5DMQ3
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G06182g
gene id: 559295:KLTH0G06182g
uniprot id: C5DM58
names: Similarity
messages: Belongs to the group II decarboxylase family.

559295:KLTH0E04620g
gene id: 559295:KLTH0E04620g
uniprot id: C5DHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

559295:KLTH0H09526g
gene id: 559295:KLTH0H09526g
uniprot id: C5E316
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

559295:KLTH0D02398g
gene id: 559295:KLTH0D02398g
uniprot id: C5DG49
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

559295:KLTH0E11462g
gene id: 559295:KLTH0E11462g
uniprot id: C5DIC6
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

559295:KLTH0H11022g
gene id: 559295:KLTH0H11022g
uniprot id: C5E378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

559295:KLTH0F00660g
gene id: 559295:KLTH0F00660g
uniprot id: C5DJZ9
names: Similarity
messages: Belongs to the MT-A70-like family.

559295:KLTH0H07590g
gene id: 559295:KLTH0H07590g
uniprot id: C5E2T6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D15246g
gene id: 559295:KLTH0D15246g
uniprot id: C5DFI0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H00946g
gene id: 559295:KLTH0H00946g
uniprot id: C5E1Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. CPD1 family.
messages: Golgi apparatus
messages: Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.

559295:KLTH0D11990g
gene id: 559295:KLTH0D11990g
uniprot id: C5DF39
names: Similarity
messages: Belongs to the AAA ATPase family.

559295:KLTH0H07216g
gene id: 559295:KLTH0H07216g
uniprot id: C5E2S0
names: Similarity
messages: Belongs to the COG3 family.

559295:KLTH0A07150g
gene id: 559295:KLTH0A07150g
uniprot id: C5DC20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

559295:KLTH0G15268g
gene id: 559295:KLTH0G15268g
uniprot id: C5DN99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

559295:KLTH0D11286g
gene id: 559295:KLTH0D11286g
uniprot id: C5DF07
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

559295:KLTH0D15554g
gene id: 559295:KLTH0D15554g
uniprot id: C5DFJ3
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

559295:KLTH0C09306g
gene id: 559295:KLTH0C09306g
uniprot id: C5DEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

559295:KLTH0E06534g
gene id: 559295:KLTH0E06534g
uniprot id: C5DHR5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

559295:KLTH0G14300g
gene id: 559295:KLTH0G14300g
uniprot id: C5DN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

559295:KLTH0B07040g
gene id: 559295:KLTH0B07040g
uniprot id: C5DCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

559295:KLTH0E04048g
gene id: 559295:KLTH0E04048g
uniprot id: C5DHG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

559295:KLTH0G15092g
gene id: 559295:KLTH0G15092g
uniprot id: C5DN91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

559295:KLTH0B04510g
gene id: 559295:KLTH0B04510g
uniprot id: C5DCN4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

559295:KLTH0H08118g
gene id: 559295:KLTH0H08118g
uniprot id: C5E2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

559295:KLTH0F11858g
gene id: 559295:KLTH0F11858g
uniprot id: C5DLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

559295:KLTH0H00924g
gene id: 559295:KLTH0H00924g
uniprot id: C5E1Z7
names: Similarity
messages: Belongs to the TFIIB family.

559295:KLTH0F12342g
gene id: 559295:KLTH0F12342g
uniprot id: C5DLE3
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

559295:KLTH0F19294g
gene id: 559295:KLTH0F19294g
uniprot id: C5DJU9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.

559295:KLTH0F11902g
gene id: 559295:KLTH0F11902g
uniprot id: C5DLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0E02068g
gene id: 559295:KLTH0E02068g
uniprot id: C5DH81
names: Similarity
messages: Belongs to the peptidase C12 family.

559295:KLTH0E13156g
gene id: 559295:KLTH0E13156g
uniprot id: C5DIK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

559295:KLTH0F15532g
gene id: 559295:KLTH0F15532g
uniprot id: C5DJD4
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

559295:KLTH0E05984g
gene id: 559295:KLTH0E05984g
uniprot id: C5DHP4
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

559295:KLTH0F08140g
gene id: 559295:KLTH0F08140g
uniprot id: C5DKW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0F08932g
gene id: 559295:KLTH0F08932g
uniprot id: C5DL04
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0A04136g
gene id: 559295:KLTH0A04136g
uniprot id: C5DBN7
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity.

559295:KLTH0G16676g
gene id: 559295:KLTH0G16676g
uniprot id: C5DNG1
names: Similarity
messages: Belongs to the PP2C family.

559295:KLTH0F18480g
gene id: 559295:KLTH0F18480g
uniprot id: C5DJR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

559295:KLTH0A04796g
gene id: 559295:KLTH0A04796g
uniprot id: C5DBR6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0D07964g
gene id: 559295:KLTH0D07964g
uniprot id: C5DGS9
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0A07546g
gene id: 559295:KLTH0A07546g
uniprot id: C5DC38
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0C08492g
gene id: 559295:KLTH0C08492g
uniprot id: C5DEE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

559295:KLTH0B02750g
gene id: 559295:KLTH0B02750g
uniprot id: C5DCG0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F05500g
gene id: 559295:KLTH0F05500g
uniprot id: C5DKK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F12386g
gene id: 559295:KLTH0F12386g
uniprot id: C5DLE5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A04774g
gene id: 559295:KLTH0A04774g
uniprot id: C5DBR5
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

559295:KLTH0F05258g
gene id: 559295:KLTH0F05258g
uniprot id: C5DKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OAF3 family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus
messages: Transcriptional inhibitor with a significantly increased number of target genes in response to oleate.

559295:KLTH0F04400g
gene id: 559295:KLTH0F04400g
uniprot id: C5DKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

559295:KLTH0D16412g
gene id: 559295:KLTH0D16412g
uniprot id: C5DFM9
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

559295:KLTH0G04510g
gene id: 559295:KLTH0G04510g
uniprot id: C5DLY5
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

559295:KLTH0H01782g
gene id: 559295:KLTH0H01782g
uniprot id: C5E233
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

559295:KLTH0B08954g
gene id: 559295:KLTH0B08954g
uniprot id: C5DD76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: telomere

559295:KLTH0G18150g
gene id: 559295:KLTH0G18150g
uniprot id: C5DNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

559295:KLTH0C07810g
gene id: 559295:KLTH0C07810g
uniprot id: C5DEB4
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

559295:KLTH0C09372g
gene id: 559295:KLTH0C09372g
uniprot id: C5DEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0A02530g
gene id: 559295:KLTH0A02530g
uniprot id: C5DBH0
names: Similarity
messages: Belongs to the NEMF family.

559295:KLTH0C01760g
gene id: 559295:KLTH0C01760g
uniprot id: C5DDK6
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

559295:KLTH0G01782g
gene id: 559295:KLTH0G01782g
uniprot id: C5DLM1
names: Function
names: Similarity
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.

559295:KLTH0D04532g
gene id: 559295:KLTH0D04532g
uniprot id: C5DGD9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

559295:KLTH0G05258g
gene id: 559295:KLTH0G05258g
uniprot id: C5DM19
names: Similarity
messages: Belongs to the syntaxin family.

559295:KLTH0E04554g
gene id: 559295:KLTH0E04554g
uniprot id: C5DHI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

559295:KLTH0H14278g
gene id: 559295:KLTH0H14278g
uniprot id: C5E3K3
names: Similarity
messages: Belongs to the PET191 family.

559295:KLTH0F01320g
gene id: 559295:KLTH0F01320g
uniprot id: C5DK29
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0F13486g
gene id: 559295:KLTH0F13486g
uniprot id: C5DJ49
names: Similarity
messages: Belongs to the MNN1/MNT family.

559295:KLTH0C09130g
gene id: 559295:KLTH0C09130g
uniprot id: C5DEH0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F13046g
gene id: 559295:KLTH0F13046g
uniprot id: C5DJ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRC22 family.
messages: Endoplasmic reticulum membrane
messages: Is probably involved in a pathway contributing to genomic integrity.

559295:KLTH0H01870g
gene id: 559295:KLTH0H01870g
uniprot id: C5E237
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

559295:KLTH0H11418g
gene id: 559295:KLTH0H11418g
uniprot id: C5E393
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

559295:KLTH0D10318g
gene id: 559295:KLTH0D10318g
uniprot id: C5DEW5
names: Similarity
messages: Belongs to the peptidase S9B family.

559295:KLTH0D11594g
gene id: 559295:KLTH0D11594g
uniprot id: C5DF21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

559295:KLTH0H07766g
gene id: 559295:KLTH0H07766g
uniprot id: C5E2U4
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

559295:KLTH0G14542g
gene id: 559295:KLTH0G14542g
uniprot id: C5DN66
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

559295:KLTH0D13464g
gene id: 559295:KLTH0D13464g
uniprot id: C5DFA2
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

559295:KLTH0C10758g
gene id: 559295:KLTH0C10758g
uniprot id: C5DEN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

559295:KLTH0G04598g
gene id: 559295:KLTH0G04598g
uniprot id: C5DLY9
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

559295:KLTH0F11352g
gene id: 559295:KLTH0F11352g
uniprot id: C5DLA3
names: Similarity
messages: Belongs to the CCZ1 family.

559295:KLTH0F01694g
gene id: 559295:KLTH0F01694g
uniprot id: C5DK46
names: Similarity
messages: Belongs to the multicopper oxidase family.

559295:KLTH0D03014g
gene id: 559295:KLTH0D03014g
uniprot id: C5DG77
names: Similarity
messages: Belongs to the COG4 family.

559295:KLTH0G10186g
gene id: 559295:KLTH0G10186g
uniprot id: C5DMM8
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

559295:KLTH0F19448g
gene id: 559295:KLTH0F19448g
uniprot id: C5DJV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

559295:KLTH0G04994g
gene id: 559295:KLTH0G04994g
uniprot id: C5DM07
names: Function
names: Subcellular Location Annotation
messages: Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

559295:KLTH0H10054g
gene id: 559295:KLTH0H10054g
uniprot id: C5E338
names: Similarity
messages: Belongs to the peptidase M28 family.

559295:KLTH0G06952g
gene id: 559295:KLTH0G06952g
uniprot id: C5DM92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Nucleus
messages: telomere

559295:KLTH0G13420g
gene id: 559295:KLTH0G13420g
uniprot id: C5DN17
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

559295:KLTH0C05412g
gene id: 559295:KLTH0C05412g
uniprot id: C5DE11
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

559295:KLTH0F11660g
gene id: 559295:KLTH0F11660g
uniprot id: C5DLB7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

559295:KLTH0D09042g
gene id: 559295:KLTH0D09042g
uniprot id: C5DGX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

559295:KLTH0E07964g
gene id: 559295:KLTH0E07964g
uniprot id: C5DHX8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0E11484g
gene id: 559295:KLTH0E11484g
uniprot id: C5DIC7
names: Similarity
messages: Belongs to the SKP1 family.

559295:KLTH0E09350g
gene id: 559295:KLTH0E09350g
uniprot id: C5DI33
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

559295:KLTH0B03586g
gene id: 559295:KLTH0B03586g
uniprot id: C5DCJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

559295:KLTH0A04070g
gene id: 559295:KLTH0A04070g
uniprot id: C5DBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0E16720g
gene id: 559295:KLTH0E16720g
uniprot id: C5DJ09
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E15466g
gene id: 559295:KLTH0E15466g
uniprot id: C5DIV4
names: Similarity
messages: Belongs to the phospholipase D family.

559295:KLTH0G07678g
gene id: 559295:KLTH0G07678g
uniprot id: C5DMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

559295:KLTH0E13288g
gene id: 559295:KLTH0E13288g
uniprot id: C5DIK7
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

559295:KLTH0B01386g
gene id: 559295:KLTH0B01386g
uniprot id: C5DCA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

559295:KLTH0A01474g
gene id: 559295:KLTH0A01474g
uniprot id: C5DBC8
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

559295:KLTH0G17446g
gene id: 559295:KLTH0G17446g
uniprot id: C5DNJ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.

559295:KLTH0A02618g
gene id: 559295:KLTH0A02618g
uniprot id: C5DBH2
names: Similarity
messages: Belongs to the peptidase C48 family.

559295:KLTH0G06930g
gene id: 559295:KLTH0G06930g
uniprot id: C5DM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

559295:KLTH0E01914g
gene id: 559295:KLTH0E01914g
uniprot id: C5DH74
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

559295:KLTH0E05610g
gene id: 559295:KLTH0E05610g
uniprot id: C5DHM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

559295:KLTH0G03982g
gene id: 559295:KLTH0G03982g
uniprot id: C5DLW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

559295:KLTH0C04994g
gene id: 559295:KLTH0C04994g
uniprot id: C5DDZ3
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

559295:KLTH0B02574g
gene id: 559295:KLTH0B02574g
uniprot id: C5DCF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NMT1/THI5 family.
messages: Homodimer.
messages: Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.

559295:KLTH0F02442g
gene id: 559295:KLTH0F02442g
uniprot id: C5DK79
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

559295:KLTH0G11110g
gene id: 559295:KLTH0G11110g
uniprot id: C5DMR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F16236g
gene id: 559295:KLTH0F16236g
uniprot id: C5DJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

559295:KLTH0H15708g
gene id: 559295:KLTH0H15708g
uniprot id: C5E3R4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

559295:KLTH0H13288g
gene id: 559295:KLTH0H13288g
uniprot id: C5E3G2
names: Similarity
messages: Belongs to the syntaxin family.

559295:KLTH0C06072g
gene id: 559295:KLTH0C06072g
uniprot id: C5DE40
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

559295:KLTH0B06468g
gene id: 559295:KLTH0B06468g
uniprot id: C5DCX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Interacts with CHS3.

559295:KLTH0F04268g
gene id: 559295:KLTH0F04268g
uniprot id: C5DKF5
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

559295:KLTH0G06028g
gene id: 559295:KLTH0G06028g
uniprot id: C5DM51
names: Similarity
messages: Belongs to the PIH1 family.

559295:KLTH0A05852g
gene id: 559295:KLTH0A05852g
uniprot id: C5DBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

559295:KLTH0D01144g
gene id: 559295:KLTH0D01144g
uniprot id: C5DFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

559295:KLTH0G06534g
gene id: 559295:KLTH0G06534g
uniprot id: C5DM73
names: Similarity
messages: Belongs to the glutaredoxin family.

559295:KLTH0G10582g
gene id: 559295:KLTH0G10582g
uniprot id: C5DMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

559295:KLTH0G06666g
gene id: 559295:KLTH0G06666g
uniprot id: C5DM79
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

559295:KLTH0B00220g
gene id: 559295:KLTH0B00220g
uniprot id: C5DC59
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0G08338g
gene id: 559295:KLTH0G08338g
uniprot id: C5DMF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

559295:KLTH0C11286g
gene id: 559295:KLTH0C11286g
uniprot id: C5DEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

559295:KLTH0C09878g
gene id: 559295:KLTH0C09878g
uniprot id: C5DEJ9
names: Similarity
messages: Belongs to the VPS52 family.

559295:KLTH0E01078g
gene id: 559295:KLTH0E01078g
uniprot id: C5DH37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

559295:KLTH0D04576g
gene id: 559295:KLTH0D04576g
uniprot id: C5DGE1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0F12100g
gene id: 559295:KLTH0F12100g
uniprot id: C5DLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

559295:KLTH0F16808g
gene id: 559295:KLTH0F16808g
uniprot id: C5DJJ0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

559295:KLTH0G01320g
gene id: 559295:KLTH0G01320g
uniprot id: C5DLK0
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H06974g
gene id: 559295:KLTH0H06974g
uniprot id: C5E2Q9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

559295:KLTH0F05610g
gene id: 559295:KLTH0F05610g
uniprot id: C5DKL1
names: Function
names: Similarity
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

559295:KLTH0H04444g
gene id: 559295:KLTH0H04444g
uniprot id: C5E2F1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C05918g
gene id: 559295:KLTH0C05918g
uniprot id: C5DE33
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

559295:KLTH0D14630g
gene id: 559295:KLTH0D14630g
uniprot id: C5DFF3
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

559295:KLTH0G17820g
gene id: 559295:KLTH0G17820g
uniprot id: C5DNK6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

559295:KLTH0H07304g
gene id: 559295:KLTH0H07304g
uniprot id: C5E2S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

559295:KLTH0G06732g
gene id: 559295:KLTH0G06732g
uniprot id: C5DM82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0E03982g
gene id: 559295:KLTH0E03982g
uniprot id: C5DHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

559295:KLTH0G17952g
gene id: 559295:KLTH0G17952g
uniprot id: C5DNL2
names: Similarity
messages: Belongs to the CWC22 family.

559295:KLTH0G06842g
gene id: 559295:KLTH0G06842g
uniprot id: C5DM87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

559295:KLTH0G19118g
gene id: 559295:KLTH0G19118g
uniprot id: C5DNR0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

559295:KLTH0E14740g
gene id: 559295:KLTH0E14740g
uniprot id: C5DIS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

559295:KLTH0G06358g
gene id: 559295:KLTH0G06358g
uniprot id: C5DM66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

559295:KLTH0C04180g
gene id: 559295:KLTH0C04180g
uniprot id: C5DDV8
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0D15004g
gene id: 559295:KLTH0D15004g
uniprot id: C5DFG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

559295:KLTH0G08602g
gene id: 559295:KLTH0G08602g
uniprot id: C5DMG0
names: Similarity
messages: Belongs to the MAD2 family.

559295:KLTH0H12210g
gene id: 559295:KLTH0H12210g
uniprot id: C5E3C5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

559295:KLTH0A04510g
gene id: 559295:KLTH0A04510g
uniprot id: C5DBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RGI1 family.
messages: Cell membrane
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.

559295:KLTH0D00682g
gene id: 559295:KLTH0D00682g
uniprot id: C5DFX3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

559295:KLTH0D06996g
gene id: 559295:KLTH0D06996g
uniprot id: C5DGP5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

559295:KLTH0E06248g
gene id: 559295:KLTH0E06248g
uniprot id: C5DHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
messages: Vacuole membrane

559295:KLTH0F03234g
gene id: 559295:KLTH0F03234g
uniprot id: C5DKB4
names: Similarity
messages: Belongs to the SUI1 family.

559295:KLTH0C08910g
gene id: 559295:KLTH0C08910g
uniprot id: C5DEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

559295:KLTH0E11088g
gene id: 559295:KLTH0E11088g
uniprot id: C5DIB0
names: Function
names: Similarity
messages: Belongs to the NUP family.
messages: Nucleoside permease that transports adenosine and guanosine.

559295:KLTH0D04884g
gene id: 559295:KLTH0D04884g
uniprot id: C5DGF4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0F01958g
gene id: 559295:KLTH0F01958g
uniprot id: C5DK57
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

559295:KLTH0H15268g
gene id: 559295:KLTH0H15268g
uniprot id: C5E3P5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C09900g
gene id: 559295:KLTH0C09900g
uniprot id: C5DEK0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

559295:KLTH0B03410g
gene id: 559295:KLTH0B03410g
uniprot id: C5DCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

559295:KLTH0G12716g
gene id: 559295:KLTH0G12716g
uniprot id: C5DMY7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A07106g
gene id: 559295:KLTH0A07106g
uniprot id: C5DC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

559295:KLTH0F09218g
gene id: 559295:KLTH0F09218g
uniprot id: C5DL16
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

559295:KLTH0G07128g
gene id: 559295:KLTH0G07128g
uniprot id: C5DMA0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

559295:KLTH0E11550g
gene id: 559295:KLTH0E11550g
uniprot id: C5DID0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

559295:KLTH0G09306g
gene id: 559295:KLTH0G09306g
uniprot id: C5DMI9
names: Similarity
messages: Belongs to the SUN family.

559295:KLTH0D10692g
gene id: 559295:KLTH0D10692g
uniprot id: C5DEY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

559295:KLTH0E11110g
gene id: 559295:KLTH0E11110g
uniprot id: C5DIB1
names: Similarity
messages: Belongs to the protein kinase superfamily.

559295:KLTH0F15180g
gene id: 559295:KLTH0F15180g
uniprot id: C5DJC0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

559295:KLTH0A04246g
gene id: 559295:KLTH0A04246g
uniprot id: C5DBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

559295:KLTH0E02464g
gene id: 559295:KLTH0E02464g
uniprot id: C5DH96
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

559295:KLTH0D06622g
gene id: 559295:KLTH0D06622g
uniprot id: C5DGM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0F02332g
gene id: 559295:KLTH0F02332g
uniprot id: C5DK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

559295:KLTH0F04378g
gene id: 559295:KLTH0F04378g
uniprot id: C5DKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

559295:KLTH0E12012g
gene id: 559295:KLTH0E12012g
uniprot id: C5DIF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EXO5 family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Mitochondrion
messages: Monomer.
messages: Single strand DNA specific 5'exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).

559295:KLTH0B04708g
gene id: 559295:KLTH0B04708g
uniprot id: C5DCP3
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

559295:KLTH0F18898g
gene id: 559295:KLTH0F18898g
uniprot id: C5DJT1
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

559295:KLTH0F02134g
gene id: 559295:KLTH0F02134g
uniprot id: C5DK65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0A05588g
gene id: 559295:KLTH0A05588g
uniprot id: C5DBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BBP1 family.
messages: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. Connects the central plaque of the SPB with the half-bridge. Required for proper localization of CDC5 at the SPB and for proper M-phase progression (By similarity).
messages: Homodimer.
messages: spindle pole body

559295:KLTH0A00704g
gene id: 559295:KLTH0A00704g
uniprot id: C5DB94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Preautophagosomal structure

559295:KLTH0C07964g
gene id: 559295:KLTH0C07964g
uniprot id: C5DEC0
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0F14740g
gene id: 559295:KLTH0F14740g
uniprot id: C5DJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

559295:KLTH0F19690g
gene id: 559295:KLTH0F19690g
uniprot id: C5DJW7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

559295:KLTH0E05192g
gene id: 559295:KLTH0E05192g
uniprot id: C5DHL0
names: Similarity
messages: Belongs to the cyclin family.

559295:KLTH0G03366g
gene id: 559295:KLTH0G03366g
uniprot id: C5DLT7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B03542g
gene id: 559295:KLTH0B03542g
uniprot id: C5DCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0D08514g
gene id: 559295:KLTH0D08514g
uniprot id: C5DGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

559295:KLTH0B01474g
gene id: 559295:KLTH0B01474g
uniprot id: C5DCA5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

559295:KLTH0C04510g
gene id: 559295:KLTH0C04510g
uniprot id: C5DDX3
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

559295:KLTH0F14960g
gene id: 559295:KLTH0F14960g
uniprot id: C5DJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

559295:KLTH0F06050g
gene id: 559295:KLTH0F06050g
uniprot id: C5DKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

559295:KLTH0H15906g
gene id: 559295:KLTH0H15906g
uniprot id: C5E3S3
names: Similarity
messages: Belongs to the Luc7 family.

559295:KLTH0A00616g
gene id: 559295:KLTH0A00616g
uniprot id: C5DB90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

559295:KLTH0D11132g
gene id: 559295:KLTH0D11132g
uniprot id: C5DF00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

559295:KLTH0D13926g
gene id: 559295:KLTH0D13926g
uniprot id: C5DFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

559295:KLTH0G01870g
gene id: 559295:KLTH0G01870g
uniprot id: C5DLM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

559295:KLTH0G16632g
gene id: 559295:KLTH0G16632g
uniprot id: C5DNF9
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

559295:KLTH0A06336g
gene id: 559295:KLTH0A06336g
uniprot id: C5DBY5
names: Similarity
messages: Belongs to the threonine synthase family.

559295:KLTH0F03124g
gene id: 559295:KLTH0F03124g
uniprot id: C5DKA9
names: Function
names: Similarity
messages: Belongs to the DPH4 family.
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

559295:KLTH0E03212g
gene id: 559295:KLTH0E03212g
uniprot id: C5DHC6
names: Similarity
messages: Belongs to the peptidase M20A family.

559295:KLTH0D05170g
gene id: 559295:KLTH0D05170g
uniprot id: C5DGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrion inner membrane
messages: Probable mitochondrial mRNA stabilization factor.

559295:KLTH0G07106g
gene id: 559295:KLTH0G07106g
uniprot id: C5DM99
names: Similarity
messages: Belongs to the peptidase M16 family.

559295:KLTH0F12254g
gene id: 559295:KLTH0F12254g
uniprot id: C5DLE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

559295:KLTH0F03102g
gene id: 559295:KLTH0F03102g
uniprot id: C5DKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

559295:KLTH0H07524g
gene id: 559295:KLTH0H07524g
uniprot id: C5E2T3
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

559295:KLTH0F01144g
gene id: 559295:KLTH0F01144g
uniprot id: C5DK21
names: Similarity
messages: Belongs to the hexokinase family.

559295:KLTH0H11066g
gene id: 559295:KLTH0H11066g
uniprot id: C5E380
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

559295:KLTH0G17600g
gene id: 559295:KLTH0G17600g
uniprot id: C5DNJ7
names: Subcellular Location Annotation
messages: Cytoplasm

559295:KLTH0B03630g
gene id: 559295:KLTH0B03630g
uniprot id: C5DCJ8
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

559295:KLTH0E10208g
gene id: 559295:KLTH0E10208g
uniprot id: C5DI72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

559295:KLTH0C02904g
gene id: 559295:KLTH0C02904g
uniprot id: C5DDQ5
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0E01804g
gene id: 559295:KLTH0E01804g
uniprot id: C5DH69
names: Similarity
messages: Belongs to the peptidase M20A family.

559295:KLTH0D17050g
gene id: 559295:KLTH0D17050g
uniprot id: C5DFQ4
names: Subcellular Location Annotation
messages: Cell surface

559295:KLTH0D09944g
gene id: 559295:KLTH0D09944g
uniprot id: C5DEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

559295:KLTH0B01628g
gene id: 559295:KLTH0B01628g
uniprot id: C5DCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Nucleus

559295:KLTH0D11462g
gene id: 559295:KLTH0D11462g
uniprot id: C5DF15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0G03916g
gene id: 559295:KLTH0G03916g
uniprot id: C5DLV8
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

559295:KLTH0B06798g
gene id: 559295:KLTH0B06798g
uniprot id: C5DCY4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

559295:KLTH0G15422g
gene id: 559295:KLTH0G15422g
uniprot id: C5DNA5
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D15092g
gene id: 559295:KLTH0D15092g
uniprot id: C5DFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Nucleus

559295:KLTH0F06160g
gene id: 559295:KLTH0F06160g
uniprot id: C5DKN5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

559295:KLTH0D17974g
gene id: 559295:KLTH0D17974g
uniprot id: C5DFU3
names: Similarity
messages: Belongs to the allantoicase family.

559295:KLTH0E08382g
gene id: 559295:KLTH0E08382g
uniprot id: C5DHZ3
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

559295:KLTH0F11594g
gene id: 559295:KLTH0F11594g
uniprot id: C5DLB4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0C11616g
gene id: 559295:KLTH0C11616g
uniprot id: C5DES1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C07414g
gene id: 559295:KLTH0C07414g
uniprot id: C5DE98
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

559295:KLTH0C02200g
gene id: 559295:KLTH0C02200g
uniprot id: C5DDM5
names: Similarity
messages: Belongs to the ZPR1 family.

559295:KLTH0H06952g
gene id: 559295:KLTH0H06952g
uniprot id: C5E2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

559295:KLTH0G17512g
gene id: 559295:KLTH0G17512g
uniprot id: C5DNJ3
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

559295:KLTH0D08338g
gene id: 559295:KLTH0D08338g
uniprot id: C5DGU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

559295:KLTH0H06600g
gene id: 559295:KLTH0H06600g
uniprot id: C5E2P3
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

559295:KLTH0E05016g
gene id: 559295:KLTH0E05016g
uniprot id: C5DHK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 22 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0F14872g
gene id: 559295:KLTH0F14872g
uniprot id: C5DJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

559295:KLTH0H02266g
gene id: 559295:KLTH0H02266g
uniprot id: C5E255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

559295:KLTH0D01474g
gene id: 559295:KLTH0D01474g
uniprot id: C5DG08
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F09504g
gene id: 559295:KLTH0F09504g
uniprot id: C5DL29
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

559295:KLTH0C10626g
gene id: 559295:KLTH0C10626g
uniprot id: C5DEN2
names: Similarity
messages: Belongs to the OPA3 family.

559295:KLTH0A04664g
gene id: 559295:KLTH0A04664g
uniprot id: C5DBR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

559295:KLTH0B06446g
gene id: 559295:KLTH0B06446g
uniprot id: C5DCX0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

559295:KLTH0B09856g
gene id: 559295:KLTH0B09856g
uniprot id: C5DDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

559295:KLTH0E16346g
gene id: 559295:KLTH0E16346g
uniprot id: C5DIZ3
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0G10142g
gene id: 559295:KLTH0G10142g
uniprot id: C5DMM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

559295:KLTH0E00836g
gene id: 559295:KLTH0E00836g
uniprot id: C5DH26
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

559295:KLTH0H03300g
gene id: 559295:KLTH0H03300g
uniprot id: C5E2A2
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

559295:KLTH0D09350g
gene id: 559295:KLTH0D09350g
uniprot id: C5DGY8
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

559295:KLTH0C11044g
gene id: 559295:KLTH0C11044g
uniprot id: C5DEP8
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D06160g
gene id: 559295:KLTH0D06160g
uniprot id: C5DGK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

559295:KLTH0B03608g
gene id: 559295:KLTH0B03608g
uniprot id: C5DCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

559295:KLTH0E05104g
gene id: 559295:KLTH0E05104g
uniprot id: C5DHK7
names: Similarity
messages: Belongs to the peptidase M16 family.

559295:KLTH0E01342g
gene id: 559295:KLTH0E01342g
uniprot id: C5DH49
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

559295:KLTH0F04884g
gene id: 559295:KLTH0F04884g
uniprot id: C5DKI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

559295:KLTH0C05632g
gene id: 559295:KLTH0C05632g
uniprot id: C5DE21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

559295:KLTH0G14476g
gene id: 559295:KLTH0G14476g
uniprot id: C5DN63
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

559295:KLTH0F03058g
gene id: 559295:KLTH0F03058g
uniprot id: C5DKA6
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

559295:KLTH0H01628g
gene id: 559295:KLTH0H01628g
uniprot id: C5E226
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

559295:KLTH0F16852g
gene id: 559295:KLTH0F16852g
uniprot id: C5DJJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

559295:KLTH0G13992g
gene id: 559295:KLTH0G13992g
uniprot id: C5DN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

559295:KLTH0C05214g
gene id: 559295:KLTH0C05214g
uniprot id: C5DE03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

559295:KLTH0D10802g
gene id: 559295:KLTH0D10802g
uniprot id: C5DEY6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

559295:KLTH0D09856g
gene id: 559295:KLTH0D09856g
uniprot id: C5DEU5
names: Similarity
messages: Belongs to the NOC2 family.

559295:KLTH0F16962g
gene id: 559295:KLTH0F16962g
uniprot id: C5DJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

559295:KLTH0A00242g
gene id: 559295:KLTH0A00242g
uniprot id: C5DB77
names: Similarity
messages: Belongs to the peptidase C56 family.

559295:KLTH0A00902g
gene id: 559295:KLTH0A00902g
uniprot id: C5DBA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

559295:KLTH0B09108g
gene id: 559295:KLTH0B09108g
uniprot id: C5DD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

559295:KLTH0D02288g
gene id: 559295:KLTH0D02288g
uniprot id: C5DG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

559295:KLTH0H13068g
gene id: 559295:KLTH0H13068g
uniprot id: C5E3F8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

559295:KLTH0G15598g
gene id: 559295:KLTH0G15598g
uniprot id: C5DNB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

559295:KLTH0E03762g
gene id: 559295:KLTH0E03762g
uniprot id: C5DHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Membrane
messages: Peroxisome membrane

559295:KLTH0E06160g
gene id: 559295:KLTH0E06160g
uniprot id: C5DHQ2
names: Similarity
messages: Belongs to the peptidase M24B family.

559295:KLTH0C11836g
gene id: 559295:KLTH0C11836g
uniprot id: C5DES7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0E02310g
gene id: 559295:KLTH0E02310g
uniprot id: C5DH90
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G05588g
gene id: 559295:KLTH0G05588g
uniprot id: C5DM32
names: Similarity
messages: Belongs to the GroES chaperonin family.

559295:KLTH0F16478g
gene id: 559295:KLTH0F16478g
uniprot id: C5DJH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1).
messages: Cytoplasm

559295:KLTH0E10692g
gene id: 559295:KLTH0E10692g
uniprot id: C5DI93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

559295:KLTH0G10736g
gene id: 559295:KLTH0G10736g
uniprot id: C5DMQ2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H00814g
gene id: 559295:KLTH0H00814g
uniprot id: C5E1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

559295:KLTH0D01958g
gene id: 559295:KLTH0D01958g
uniprot id: C5DG29
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

559295:KLTH0F16500g
gene id: 559295:KLTH0F16500g
uniprot id: C5DJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPC110 family.
messages: Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth (By similarity).
messages: Homodimer.
messages: Nucleus
messages: spindle pole body

559295:KLTH0G08646g
gene id: 559295:KLTH0G08646g
uniprot id: C5DMG2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

559295:KLTH0F03190g
gene id: 559295:KLTH0F03190g
uniprot id: C5DKB2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

559295:KLTH0G18920g
gene id: 559295:KLTH0G18920g
uniprot id: C5DNQ1
names: Similarity
messages: Belongs to the FYV7 family.

559295:KLTH0E04334g
gene id: 559295:KLTH0E04334g
uniprot id: C5DHH3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

559295:KLTH0G16698g
gene id: 559295:KLTH0G16698g
uniprot id: C5DNG2
names: Similarity
messages: Belongs to the AAA ATPase family.

559295:KLTH0F16346g
gene id: 559295:KLTH0F16346g
uniprot id: C5DJG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

559295:KLTH0C06710g
gene id: 559295:KLTH0C06710g
uniprot id: C5DE68
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

559295:KLTH0D04774g
gene id: 559295:KLTH0D04774g
uniprot id: C5DGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: telomere

559295:KLTH0H03938g
gene id: 559295:KLTH0H03938g
uniprot id: C5E2D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

559295:KLTH0H06732g
gene id: 559295:KLTH0H06732g
uniprot id: C5E2P9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

559295:KLTH0B04356g
gene id: 559295:KLTH0B04356g
uniprot id: C5DCM7
names: Similarity
messages: Belongs to the multicopper oxidase family.

559295:KLTH0A06160g
gene id: 559295:KLTH0A06160g
uniprot id: C5DBX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

559295:KLTH0F02838g
gene id: 559295:KLTH0F02838g
uniprot id: C5DK96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

559295:KLTH0H08910g
gene id: 559295:KLTH0H08910g
uniprot id: C5E2Y8
names: Similarity
messages: Belongs to the TACO1 family.

559295:KLTH0F10934g
gene id: 559295:KLTH0F10934g
uniprot id: C5DL89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX9 family.
messages: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3 snoRNA.
messages: Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1). May be involved in the movements of the replication forks.
messages: nucleolus

559295:KLTH0F13178g
gene id: 559295:KLTH0F13178g
uniprot id: C5DJ36
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

559295:KLTH0H05236g
gene id: 559295:KLTH0H05236g
uniprot id: C5E2I4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D16764g
gene id: 559295:KLTH0D16764g
uniprot id: C5DFP2
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.

559295:KLTH0C05390g
gene id: 559295:KLTH0C05390g
uniprot id: C5DE10
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

559295:KLTH0B10340g
gene id: 559295:KLTH0B10340g
uniprot id: C5DDD4
names: Function
names: Similarity
messages: Belongs to the NUP family.
messages: Nucleoside permease that transports adenosine and guanosine.

559295:KLTH0H14718g
gene id: 559295:KLTH0H14718g
uniprot id: C5E3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

559295:KLTH0D16104g
gene id: 559295:KLTH0D16104g
uniprot id: C5DFL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

559295:KLTH0G02508g
gene id: 559295:KLTH0G02508g
uniprot id: C5DLP9
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

559295:KLTH0A06776g
gene id: 559295:KLTH0A06776g
uniprot id: C5DC03
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

559295:KLTH0F08426g
gene id: 559295:KLTH0F08426g
uniprot id: C5DKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

559295:KLTH0E15752g
gene id: 559295:KLTH0E15752g
uniprot id: C5DIW7
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G04818g
gene id: 559295:KLTH0G04818g
uniprot id: C5DLZ9
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

559295:KLTH0D15488g
gene id: 559295:KLTH0D15488g
uniprot id: C5DFJ0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

559295:KLTH0H00396g
gene id: 559295:KLTH0H00396g
uniprot id: C5E1X4
names: Similarity
messages: Belongs to the NARF family.

559295:KLTH0F07788g
gene id: 559295:KLTH0F07788g
uniprot id: C5DKV3
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

559295:KLTH0C09812g
gene id: 559295:KLTH0C09812g
uniprot id: C5DEJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

559295:KLTH0H02354g
gene id: 559295:KLTH0H02354g
uniprot id: C5E259
names: Similarity
messages: Belongs to the PPP phosphatase family.

559295:KLTH0A04950g
gene id: 559295:KLTH0A04950g
uniprot id: C5DBS3
names: Similarity
messages: Belongs to the peptidase M24B family.

559295:KLTH0B07722g
gene id: 559295:KLTH0B07722g
uniprot id: C5DD24
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

559295:KLTH0D02156g
gene id: 559295:KLTH0D02156g
uniprot id: C5DG38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

559295:KLTH0A00506g
gene id: 559295:KLTH0A00506g
uniprot id: C5DB85
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

559295:KLTH0A06534g
gene id: 559295:KLTH0A06534g
uniprot id: C5DBZ2
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D06556g
gene id: 559295:KLTH0D06556g
uniprot id: C5DGM6
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

559295:KLTH0E15180g
gene id: 559295:KLTH0E15180g
uniprot id: C5DIU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

559295:KLTH0D05764g
gene id: 559295:KLTH0D05764g
uniprot id: C5DGJ3
names: Similarity
messages: Belongs to the ISF1/MBR1 family.

559295:KLTH0F17666g
gene id: 559295:KLTH0F17666g
uniprot id: C5DJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0E01848g
gene id: 559295:KLTH0E01848g
uniprot id: C5DH71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0F04642g
gene id: 559295:KLTH0F04642g
uniprot id: C5DKH2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

559295:KLTH0G17732g
gene id: 559295:KLTH0G17732g
uniprot id: C5DNK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

559295:KLTH0H01430g
gene id: 559295:KLTH0H01430g
uniprot id: C5E217
names: Similarity
messages: Belongs to the epsin family.

559295:KLTH0C02530g
gene id: 559295:KLTH0C02530g
uniprot id: C5DDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

559295:KLTH0E12936g
gene id: 559295:KLTH0E12936g
uniprot id: C5DIJ2
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

559295:KLTH0F15070g
gene id: 559295:KLTH0F15070g
uniprot id: C5DJB5
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

559295:KLTH0G07568g
gene id: 559295:KLTH0G07568g
uniprot id: C5DMB9
names: Similarity
messages: Belongs to the LTV1 family.

559295:KLTH0E11902g
gene id: 559295:KLTH0E11902g
uniprot id: C5DIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

559295:KLTH0C01078g
gene id: 559295:KLTH0C01078g
uniprot id: C5DDH7
names: Similarity
messages: Belongs to the small Tim family.

559295:KLTH0F13376g
gene id: 559295:KLTH0F13376g
uniprot id: C5DJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM21 family.
messages: Involved in mitochondrial migration along actin filaments.
messages: actin patch

559295:KLTH0H02244g
gene id: 559295:KLTH0H02244g
uniprot id: C5E254
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

559295:KLTH0A01034g
gene id: 559295:KLTH0A01034g
uniprot id: C5DBA9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B04576g
gene id: 559295:KLTH0B04576g
uniprot id: C5DCN7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.

559295:KLTH0E06556g
gene id: 559295:KLTH0E06556g
uniprot id: C5DHR6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

559295:KLTH0C03740g
gene id: 559295:KLTH0C03740g
uniprot id: C5DDT9
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

559295:KLTH0G02596g
gene id: 559295:KLTH0G02596g
uniprot id: C5DLQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0A07436g
gene id: 559295:KLTH0A07436g
uniprot id: C5DC33
names: Similarity
messages: Belongs to the TRM112 family.

559295:KLTH0F17710g
gene id: 559295:KLTH0F17710g
uniprot id: C5DJM8
names: Similarity
messages: Belongs to the RNase Z family.

559295:KLTH0D07128g
gene id: 559295:KLTH0D07128g
uniprot id: C5DGQ1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G18238g
gene id: 559295:KLTH0G18238g
uniprot id: C5DNM0
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

559295:KLTH0H08316g
gene id: 559295:KLTH0H08316g
uniprot id: C5E2W8
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

559295:KLTH0G03212g
gene id: 559295:KLTH0G03212g
uniprot id: C5DLT1
names: Similarity
messages: Belongs to the PIAS family.

559295:KLTH0D13178g
gene id: 559295:KLTH0D13178g
uniprot id: C5DF90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

559295:KLTH0H14828g
gene id: 559295:KLTH0H14828g
uniprot id: C5E3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Yeast FIT2A/YFT2 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization). Involved in phospholipid biosynthesis.
messages: Membrane

559295:KLTH0G07810g
gene id: 559295:KLTH0G07810g
uniprot id: C5DMC8
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

559295:KLTH0D05786g
gene id: 559295:KLTH0D05786g
uniprot id: C5DGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

559295:KLTH0H10208g
gene id: 559295:KLTH0H10208g
uniprot id: C5E342
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

559295:KLTH0A03278g
gene id: 559295:KLTH0A03278g
uniprot id: C5DBK1
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F04312g
gene id: 559295:KLTH0F04312g
uniprot id: C5DKF7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

559295:KLTH0F01738g
gene id: 559295:KLTH0F01738g
uniprot id: C5DK48
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

559295:KLTH0B01760g
gene id: 559295:KLTH0B01760g
uniprot id: C5DCB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

559295:KLTH0D13112g
gene id: 559295:KLTH0D13112g
uniprot id: C5DF87
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

559295:KLTH0F18876g
gene id: 559295:KLTH0F18876g
uniprot id: C5DJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

559295:KLTH0E15488g
gene id: 559295:KLTH0E15488g
uniprot id: C5DIV5
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H14938g
gene id: 559295:KLTH0H14938g
uniprot id: C5E3N1
names: Similarity
messages: Belongs to the OSBP family.

559295:KLTH0D00814g
gene id: 559295:KLTH0D00814g
uniprot id: C5DFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
messages: Nucleus

559295:KLTH0G12958g
gene id: 559295:KLTH0G12958g
uniprot id: C5DMZ6
names: Function
names: Similarity
messages: Belongs to the LCL2 family.
messages: Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.

559295:KLTH0G14146g
gene id: 559295:KLTH0G14146g
uniprot id: C5DN49
names: Similarity
messages: Belongs to the 14-3-3 family.

559295:KLTH0F08558g
gene id: 559295:KLTH0F08558g
uniprot id: C5DKY7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

559295:KLTH0B09636g
gene id: 559295:KLTH0B09636g
uniprot id: C5DDA7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

559295:KLTH0G12386g
gene id: 559295:KLTH0G12386g
uniprot id: C5DMX3
names: Similarity
messages: Belongs to the peptidase A1 family.

559295:KLTH0H08184g
gene id: 559295:KLTH0H08184g
uniprot id: C5E2W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

559295:KLTH0E03014g
gene id: 559295:KLTH0E03014g
uniprot id: C5DHB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

559295:KLTH0E10340g
gene id: 559295:KLTH0E10340g
uniprot id: C5DI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

559295:KLTH0A05566g
gene id: 559295:KLTH0A05566g
uniprot id: C5DBV1
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0H12760g
gene id: 559295:KLTH0H12760g
uniprot id: C5E3E6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H06182g
gene id: 559295:KLTH0H06182g
uniprot id: C5E2M5
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

559295:KLTH0H07084g
gene id: 559295:KLTH0H07084g
uniprot id: C5E2R4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

559295:KLTH0E10428g
gene id: 559295:KLTH0E10428g
uniprot id: C5DI81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

559295:KLTH0H12584g
gene id: 559295:KLTH0H12584g
uniprot id: C5E3D9
names: Similarity
messages: Belongs to the WrbA family.

559295:KLTH0D14476g
gene id: 559295:KLTH0D14476g
uniprot id: C5DFE6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

559295:KLTH0A02244g
gene id: 559295:KLTH0A02244g
uniprot id: C5DBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

559295:KLTH0B04598g
gene id: 559295:KLTH0B04598g
uniprot id: C5DCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

559295:KLTH0D03960g
gene id: 559295:KLTH0D03960g
uniprot id: C5DGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

559295:KLTH0D06314g
gene id: 559295:KLTH0D06314g
uniprot id: C5DGL6
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

559295:KLTH0B06776g
gene id: 559295:KLTH0B06776g
uniprot id: C5DCY3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

559295:KLTH0A03234g
gene id: 559295:KLTH0A03234g
uniprot id: C5DBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

559295:KLTH0H05698g
gene id: 559295:KLTH0H05698g
uniprot id: C5E2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

559295:KLTH0D00616g
gene id: 559295:KLTH0D00616g
uniprot id: C5DFX0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0D05280g
gene id: 559295:KLTH0D05280g
uniprot id: C5DGH1
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

559295:KLTH0G08118g
gene id: 559295:KLTH0G08118g
uniprot id: C5DME2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H05632g
gene id: 559295:KLTH0H05632g
uniprot id: C5E2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0E06644g
gene id: 559295:KLTH0E06644g
uniprot id: C5DHS0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

559295:KLTH0F07766g
gene id: 559295:KLTH0F07766g
uniprot id: C5DKV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

559295:KLTH0D12430g
gene id: 559295:KLTH0D12430g
uniprot id: C5DF58
names: Similarity
messages: Belongs to the EFR3 family.

559295:KLTH0H05610g
gene id: 559295:KLTH0H05610g
uniprot id: C5E2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

559295:KLTH0G09482g
gene id: 559295:KLTH0G09482g
uniprot id: C5DMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

559295:KLTH0C10560g
gene id: 559295:KLTH0C10560g
uniprot id: C5DEM9
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F09460g
gene id: 559295:KLTH0F09460g
uniprot id: C5DL27
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

559295:KLTH0D01628g
gene id: 559295:KLTH0D01628g
uniprot id: C5DG15
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

559295:KLTH0D16918g
gene id: 559295:KLTH0D16918g
uniprot id: C5DFP9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

559295:KLTH0G02046g
gene id: 559295:KLTH0G02046g
uniprot id: C5DLN2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

559295:KLTH0F16632g
gene id: 559295:KLTH0F16632g
uniprot id: C5DJI2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C11704g
gene id: 559295:KLTH0C11704g
uniprot id: C5DES5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

559295:KLTH0C02552g
gene id: 559295:KLTH0C02552g
uniprot id: C5DDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

559295:KLTH0C10230g
gene id: 559295:KLTH0C10230g
uniprot id: C5DEL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

559295:KLTH0D05324g
gene id: 559295:KLTH0D05324g
uniprot id: C5DGH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

559295:KLTH0D07876g
gene id: 559295:KLTH0D07876g
uniprot id: C5DGS5
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

559295:KLTH0C06842g
gene id: 559295:KLTH0C06842g
uniprot id: C5DE73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

559295:KLTH0F04708g
gene id: 559295:KLTH0F04708g
uniprot id: C5DKH5
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

559295:KLTH0E01364g
gene id: 559295:KLTH0E01364g
uniprot id: C5DH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

559295:KLTH0D02266g
gene id: 559295:KLTH0D02266g
uniprot id: C5DG43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

559295:KLTH0B09724g
gene id: 559295:KLTH0B09724g
uniprot id: C5DDB0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0A01980g
gene id: 559295:KLTH0A01980g
uniprot id: C5DBE7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

559295:KLTH0A06270g
gene id: 559295:KLTH0A06270g
uniprot id: C5DBY2
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H14586g
gene id: 559295:KLTH0H14586g
uniprot id: C5E3L6
names: Similarity
messages: Belongs to the pyridoxine kinase family.

559295:KLTH0H00902g
gene id: 559295:KLTH0H00902g
uniprot id: C5E1Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

559295:KLTH0G06050g
gene id: 559295:KLTH0G06050g
uniprot id: C5DM52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

559295:KLTH0H05104g
gene id: 559295:KLTH0H05104g
uniprot id: C5E2I0
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

559295:KLTH0D09658g
gene id: 559295:KLTH0D09658g
uniprot id: C5DET7
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

559295:KLTH0F05456g
gene id: 559295:KLTH0F05456g
uniprot id: C5DKK4
names: Cofactor
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

559295:KLTH0D16258g
gene id: 559295:KLTH0D16258g
uniprot id: C5DFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

559295:KLTH0D02354g
gene id: 559295:KLTH0D02354g
uniprot id: C5DG47
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0G19008g
gene id: 559295:KLTH0G19008g
uniprot id: C5DNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

559295:KLTH0A07832g
gene id: 559295:KLTH0A07832g
uniprot id: C5DC50
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0G12342g
gene id: 559295:KLTH0G12342g
uniprot id: C5DMX1
names: Similarity
messages: Belongs to the cullin family.

559295:KLTH0D07172g
gene id: 559295:KLTH0D07172g
uniprot id: C5DGQ3
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

559295:KLTH0D08448g
gene id: 559295:KLTH0D08448g
uniprot id: C5DGU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

559295:KLTH0D06732g
gene id: 559295:KLTH0D06732g
uniprot id: C5DGN4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

559295:KLTH0B03674g
gene id: 559295:KLTH0B03674g
uniprot id: C5DCK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0H06358g
gene id: 559295:KLTH0H06358g
uniprot id: C5E2N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

559295:KLTH0H11550g
gene id: 559295:KLTH0H11550g
uniprot id: C5E398
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferric reductase (FRE) family. AIM14 subfamily.
messages: Membrane
messages: Probable cell surface metalloreductase. May be involved in iron or copper homeostasis (By similarity).

559295:KLTH0H07370g
gene id: 559295:KLTH0H07370g
uniprot id: C5E2S7
names: Similarity
messages: Belongs to the peptidase C19 family.

559295:KLTH0E01166g
gene id: 559295:KLTH0E01166g
uniprot id: C5DH41
names: Similarity
messages: Belongs to the pantothenate synthetase family.

559295:KLTH0E11066g
gene id: 559295:KLTH0E11066g
uniprot id: C5DIA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

559295:KLTH0G05082g
gene id: 559295:KLTH0G05082g
uniprot id: C5DM11
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0B02090g
gene id: 559295:KLTH0B02090g
uniprot id: C5DCD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

559295:KLTH0D00902g
gene id: 559295:KLTH0D00902g
uniprot id: C5DFY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

559295:KLTH0C11506g
gene id: 559295:KLTH0C11506g
uniprot id: C5DER6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

559295:KLTH0A05258g
gene id: 559295:KLTH0A05258g
uniprot id: C5DBT7
names: Similarity
messages: Belongs to the IMPACT family.

559295:KLTH0D14080g
gene id: 559295:KLTH0D14080g
uniprot id: C5DFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Nucleus

559295:KLTH0G08998g
gene id: 559295:KLTH0G08998g
uniprot id: C5DMH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

559295:KLTH0F11022g
gene id: 559295:KLTH0F11022g
uniprot id: C5DL92
names: Similarity
messages: Belongs to the PHF5 family.

559295:KLTH0D12320g
gene id: 559295:KLTH0D12320g
uniprot id: C5DF54
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0E00374g
gene id: 559295:KLTH0E00374g
uniprot id: C5DH08
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

559295:KLTH0F02310g
gene id: 559295:KLTH0F02310g
uniprot id: C5DK73
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0C05038g
gene id: 559295:KLTH0C05038g
uniprot id: C5DDZ5
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0D15048g
gene id: 559295:KLTH0D15048g
uniprot id: C5DFH1
names: Similarity
messages: Belongs to the SRR1 family.

559295:KLTH0D03190g
gene id: 559295:KLTH0D03190g
uniprot id: C5DG85
names: Subcellular Location Annotation
messages: nucleolus

559295:KLTH0E12628g
gene id: 559295:KLTH0E12628g
uniprot id: C5DIH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

559295:KLTH0G15488g
gene id: 559295:KLTH0G15488g
uniprot id: C5DNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Cytoplasm

559295:KLTH0A07986g
gene id: 559295:KLTH0A07986g
uniprot id: C5DC52
names: Similarity
messages: Belongs to the DSD1 family.

559295:KLTH0G11550g
gene id: 559295:KLTH0G11550g
uniprot id: C5DMT8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

559295:KLTH0G03432g
gene id: 559295:KLTH0G03432g
uniprot id: C5DLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

559295:KLTH0H05456g
gene id: 559295:KLTH0H05456g
uniprot id: C5E2J3
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0C08866g
gene id: 559295:KLTH0C08866g
uniprot id: C5DEG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

559295:KLTH0D04026g
gene id: 559295:KLTH0D04026g
uniprot id: C5DGB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

559295:KLTH0B05676g
gene id: 559295:KLTH0B05676g
uniprot id: C5DCT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

559295:KLTH0E01738g
gene id: 559295:KLTH0E01738g
uniprot id: C5DH66
names: Similarity
messages: Belongs to the PPP4R2 family.

559295:KLTH0H11770g
gene id: 559295:KLTH0H11770g
uniprot id: C5E3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Golgi apparatus

559295:KLTH0C08360g
gene id: 559295:KLTH0C08360g
uniprot id: C5DED7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

559295:KLTH0D05478g
gene id: 559295:KLTH0D05478g
uniprot id: C5DGI0
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

559295:KLTH0F06622g
gene id: 559295:KLTH0F06622g
uniprot id: C5DKQ4
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

559295:KLTH0H14432g
gene id: 559295:KLTH0H14432g
uniprot id: C5E3L0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0H14960g
gene id: 559295:KLTH0H14960g
uniprot id: C5E3N2
names: Similarity
messages: Belongs to the asparaginase 1 family.

559295:KLTH0E10274g
gene id: 559295:KLTH0E10274g
uniprot id: C5DI74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

559295:KLTH0F02882g
gene id: 559295:KLTH0F02882g
uniprot id: C5DK98
names: Function
names: Similarity
messages: Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.
messages: In the central section; belongs to the HPPK family.

559295:KLTH0E07612g
gene id: 559295:KLTH0E07612g
uniprot id: C5DHW2
names: Similarity
messages: Belongs to the HscB family.

559295:KLTH0D15070g
gene id: 559295:KLTH0D15070g
uniprot id: C5DFH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

559295:KLTH0A01276g
gene id: 559295:KLTH0A01276g
uniprot id: C5DBB9
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

559295:KLTH0G03652g
gene id: 559295:KLTH0G03652g
uniprot id: C5DLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

559295:KLTH0F09306g
gene id: 559295:KLTH0F09306g
uniprot id: C5DL20
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

559295:KLTH0E09174g
gene id: 559295:KLTH0E09174g
uniprot id: C5DI26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

559295:KLTH0F07436g
gene id: 559295:KLTH0F07436g
uniprot id: C5DKT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

559295:KLTH0A01144g
gene id: 559295:KLTH0A01144g
uniprot id: C5DBB3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

559295:KLTH0C10802g
gene id: 559295:KLTH0C10802g
uniprot id: C5DEN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

559295:KLTH0H02882g
gene id: 559295:KLTH0H02882g
uniprot id: C5E283
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

559295:KLTH0G03322g
gene id: 559295:KLTH0G03322g
uniprot id: C5DLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

559295:KLTH0G00682g
gene id: 559295:KLTH0G00682g
uniprot id: C5DLH1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

559295:KLTH0G07414g
gene id: 559295:KLTH0G07414g
uniprot id: C5DMB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

559295:KLTH0D10890g
gene id: 559295:KLTH0D10890g
uniprot id: C5DEZ0
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0F09086g
gene id: 559295:KLTH0F09086g
uniprot id: C5DL11
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

559295:KLTH0E00242g
gene id: 559295:KLTH0E00242g
uniprot id: C5DH02
names: Subcellular Location Annotation
messages: Cell surface

559295:KLTH0C01056g
gene id: 559295:KLTH0C01056g
uniprot id: C5DDH6
names: Subcellular Location Annotation
messages: Membrane

559295:KLTH0D08690g
gene id: 559295:KLTH0D08690g
uniprot id: C5DGV9
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

559295:KLTH0H15576g
gene id: 559295:KLTH0H15576g
uniprot id: C5E3Q8
names: Similarity
messages: Belongs to the SIP5 family.

559295:KLTH0D09812g
gene id: 559295:KLTH0D09812g
uniprot id: C5DEU3
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

559295:KLTH0H07458g
gene id: 559295:KLTH0H07458g
uniprot id: C5E2T0
names: Similarity
messages: Belongs to the PPP phosphatase family.

559295:KLTH0H02596g
gene id: 559295:KLTH0H02596g
uniprot id: C5E270
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

559295:KLTH0D01320g
gene id: 559295:KLTH0D01320g
uniprot id: C5DG01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

559295:KLTH0G00880g
gene id: 559295:KLTH0G00880g
uniprot id: C5DLI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

559295:KLTH0F12408g
gene id: 559295:KLTH0F12408g
uniprot id: C5DLE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

559295:KLTH0A03454g
gene id: 559295:KLTH0A03454g
uniprot id: C5DBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

559295:KLTH0G08382g
gene id: 559295:KLTH0G08382g
uniprot id: C5DMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPIN family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1).
messages: Endosome

559295:KLTH0D10098g
gene id: 559295:KLTH0D10098g
uniprot id: C5DEV6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

559295:KLTH0B08052g
gene id: 559295:KLTH0B08052g
uniprot id: C5DD39
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

559295:KLTH0C03256g
gene id: 559295:KLTH0C03256g
uniprot id: C5DDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

559295:KLTH0E09658g
gene id: 559295:KLTH0E09658g
uniprot id: C5DI47
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

559295:KLTH0H04466g
gene id: 559295:KLTH0H04466g
uniprot id: C5E2F2
names: Similarity
messages: Belongs to the DEAD box helicase family.

559295:KLTH0E03564g
gene id: 559295:KLTH0E03564g
uniprot id: C5DHD8
names: Similarity
messages: Belongs to the TCF25 family.

559295:KLTH0D16082g
gene id: 559295:KLTH0D16082g
uniprot id: C5DFL4
names: Subcellular Location Annotation
messages: Nucleus

559295:KLTH0F10142g
gene id: 559295:KLTH0F10142g
uniprot id: C5DL55
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

559295:KLTH0A00418g
gene id: 559295:KLTH0A00418g
uniprot id: C5DB81
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

559295:KLTH0G07084g
gene id: 559295:KLTH0G07084g
uniprot id: C5DM98
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

559295:KLTH0B01914g
gene id: 559295:KLTH0B01914g
uniprot id: C5DCC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfate adenylyltransferase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.

559295:KLTH0F02860g
gene id: 559295:KLTH0F02860g
uniprot id: C5DK97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

559295:KLTH0D03256g
gene id: 559295:KLTH0D03256g
uniprot id: C5DG88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

559295:KLTH0F12804g
gene id: 559295:KLTH0F12804g
uniprot id: C5DJ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane