558173:CDOO RS09225
gene id: 558173:CDOO_RS09225
uniprot id: A0A097IH48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

558173:CDOO RS13035
gene id: 558173:CDOO_RS13035
uniprot id: A0A097IJM9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

558173:CDOO RS09320
gene id: 558173:CDOO_RS09320
uniprot id: A0A097IH84
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

558173:CDOO RS05940
gene id: 558173:CDOO_RS05940
uniprot id: A0A097IFI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS04850
gene id: 558173:CDOO_RS04850
uniprot id: A0A097IEY6
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10695
gene id: 558173:CDOO_RS10695
uniprot id: A0A097IHX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

558173:CDOO RS03855
gene id: 558173:CDOO_RS03855
uniprot id: A0A097IEE5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

558173:CDOO RS01630
gene id: 558173:CDOO_RS01630
uniprot id: A0A097IDC5
names: Subcellular Location Annotation
messages: Cytoplasm

558173:CDOO RS05735
gene id: 558173:CDOO_RS05735
uniprot id: A0A097IFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS00005
gene id: 558173:CDOO_RS00005
uniprot id: A0A097ICM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

558173:CDOO RS07830
gene id: 558173:CDOO_RS07830
uniprot id: A0A097IGH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

558173:CDOO RS05650
gene id: 558173:CDOO_RS05650
uniprot id: A0A097IFA5
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS01405
gene id: 558173:CDOO_RS01405
uniprot id: A0A097ID88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

558173:CDOO RS08455
gene id: 558173:CDOO_RS08455
uniprot id: A0A097IGT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS00330
gene id: 558173:CDOO_RS00330
uniprot id: A0A097ICV3
names: Subcellular Location Annotation
messages: Cytoplasm

558173:CDOO RS06775
gene id: 558173:CDOO_RS06775
uniprot id: A0A097IFW0
names: Similarity
messages: Belongs to the UPF0434 family.

558173:CDOO RS08640
gene id: 558173:CDOO_RS08640
uniprot id: A0A097IGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

558173:CDOO RS12020
gene id: 558173:CDOO_RS12020
uniprot id: A0A097III6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

558173:CDOO RS11200
gene id: 558173:CDOO_RS11200
uniprot id: A0A097II45
names: Similarity
messages: Belongs to the TPP enzyme family.

558173:CDOO RS08820
gene id: 558173:CDOO_RS08820
uniprot id: A0A097IGX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

558173:CDOO RS06610
gene id: 558173:CDOO_RS06610
uniprot id: A0A097IFT8
names: Similarity
messages: Belongs to the universal stress protein A family.

558173:CDOO RS08765
gene id: 558173:CDOO_RS08765
uniprot id: A0A097IGW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

558173:CDOO RS07310
gene id: 558173:CDOO_RS07310
uniprot id: A0A097IG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

558173:CDOO RS11080
gene id: 558173:CDOO_RS11080
uniprot id: A0A097II27
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

558173:CDOO RS09210
gene id: 558173:CDOO_RS09210
uniprot id: A0A097IH76
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

558173:CDOO RS01120
gene id: 558173:CDOO_RS01120
uniprot id: A0A097ID63
names: Similarity
messages: Belongs to the ABC transporter superfamily.

558173:CDOO RS08800
gene id: 558173:CDOO_RS08800
uniprot id: A0A097IGW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

558173:CDOO RS08635
gene id: 558173:CDOO_RS08635
uniprot id: A0A097IGT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

558173:CDOO RS04295
gene id: 558173:CDOO_RS04295
uniprot id: A0A097IEM2
names: Similarity
messages: Belongs to the peptidase C56 family.

558173:CDOO RS07160
gene id: 558173:CDOO_RS07160
uniprot id: A0A097IG22
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

558173:CDOO RS08850
gene id: 558173:CDOO_RS08850
uniprot id: A0A097IGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS06070
gene id: 558173:CDOO_RS06070
uniprot id: A0A097IFJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS02960
gene id: 558173:CDOO_RS02960
uniprot id: A0A097IDX7
names: Similarity
messages: Belongs to the WXG100 family.

558173:CDOO RS03270
gene id: 558173:CDOO_RS03270
uniprot id: A0A097IE30
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS01440
gene id: 558173:CDOO_RS01440
uniprot id: A0A097IDB1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

558173:CDOO RS03190
gene id: 558173:CDOO_RS03190
uniprot id: A0A097IE31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS09855
gene id: 558173:CDOO_RS09855
uniprot id: A0A097IHG5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

558173:CDOO RS08405
gene id: 558173:CDOO_RS08405
uniprot id: A0A097IGS1
names: Similarity
messages: Belongs to the PspA/IM30 family.

558173:CDOO RS12895
gene id: 558173:CDOO_RS12895
uniprot id: A0A097IJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

558173:CDOO RS05565
gene id: 558173:CDOO_RS05565
uniprot id: A0A097IFA1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07840
gene id: 558173:CDOO_RS07840
uniprot id: A0A097IGF6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS10485
gene id: 558173:CDOO_RS10485
uniprot id: A0A097IHR6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

558173:CDOO RS05845
gene id: 558173:CDOO_RS05845
uniprot id: A0A097IFE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

558173:CDOO RS03340
gene id: 558173:CDOO_RS03340
uniprot id: A0A097IE44
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

558173:CDOO RS11885
gene id: 558173:CDOO_RS11885
uniprot id: A0A097III0
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

558173:CDOO RS12965
gene id: 558173:CDOO_RS12965
uniprot id: A0A097IJ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

558173:CDOO RS01195
gene id: 558173:CDOO_RS01195
uniprot id: A0A097ID65
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

558173:CDOO RS03760
gene id: 558173:CDOO_RS03760
uniprot id: A0A097IEC6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

558173:CDOO RS08325
gene id: 558173:CDOO_RS08325
uniprot id: A0A097IGL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

558173:CDOO RS10335
gene id: 558173:CDOO_RS10335
uniprot id: A0A097IHR1
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

558173:CDOO RS02505
gene id: 558173:CDOO_RS02505
uniprot id: A0A097IDS0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

558173:CDOO RS07875
gene id: 558173:CDOO_RS07875
uniprot id: A0A097IGG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

558173:CDOO RS11440
gene id: 558173:CDOO_RS11440
uniprot id: A0A097II84
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS11785
gene id: 558173:CDOO_RS11785
uniprot id: A0A097IIG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

558173:CDOO RS10130
gene id: 558173:CDOO_RS10130
uniprot id: A0A097IHM7
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS03440
gene id: 558173:CDOO_RS03440
uniprot id: A0A097IE67
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

558173:CDOO RS09140
gene id: 558173:CDOO_RS09140
uniprot id: A0A097IH36
names: Similarity
messages: Belongs to the asparaginase 1 family.

558173:CDOO RS13270
gene id: 558173:CDOO_RS13270
uniprot id: A0A097IFU7
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06735
gene id: 558173:CDOO_RS06735
uniprot id: A0A097IFV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

558173:CDOO RS08545
gene id: 558173:CDOO_RS08545
uniprot id: A0A097IGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

558173:CDOO RS00365
gene id: 558173:CDOO_RS00365
uniprot id: A0A097ICT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

558173:CDOO RS08655
gene id: 558173:CDOO_RS08655
uniprot id: A0A097IGV0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

558173:CDOO RS07855
gene id: 558173:CDOO_RS07855
uniprot id: A0A097IGJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

558173:CDOO RS03580
gene id: 558173:CDOO_RS03580
uniprot id: A0A097IE94
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

558173:CDOO RS02775
gene id: 558173:CDOO_RS02775
uniprot id: A0A097IDW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

558173:CDOO RS07560
gene id: 558173:CDOO_RS07560
uniprot id: A0A097IGB0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

558173:CDOO RS05415
gene id: 558173:CDOO_RS05415
uniprot id: A0A097IF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

558173:CDOO RS09685
gene id: 558173:CDOO_RS09685
uniprot id: A0A097IHD7
names: Subcellular Location Annotation
messages: Secreted

558173:CDOO RS08290
gene id: 558173:CDOO_RS08290
uniprot id: A0A097IGL6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

558173:CDOO RS02555
gene id: 558173:CDOO_RS02555
uniprot id: A0A097IDT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

558173:CDOO RS08770
gene id: 558173:CDOO_RS08770
uniprot id: A0A097IGV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

558173:CDOO RS07605
gene id: 558173:CDOO_RS07605
uniprot id: A0A097IGB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

558173:CDOO RS02295
gene id: 558173:CDOO_RS02295
uniprot id: A0A097IDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

558173:CDOO RS08400
gene id: 558173:CDOO_RS08400
uniprot id: A0A097IGM6
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10480
gene id: 558173:CDOO_RS10480
uniprot id: A0A097IHU0
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

558173:CDOO RS06000
gene id: 558173:CDOO_RS06000
uniprot id: A0A097IFJ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

558173:CDOO RS09690
gene id: 558173:CDOO_RS09690
uniprot id: A0A097IHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

558173:CDOO RS00175
gene id: 558173:CDOO_RS00175
uniprot id: A0A097ICP8
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06460
gene id: 558173:CDOO_RS06460
uniprot id: A0A097IFR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

558173:CDOO RS08950
gene id: 558173:CDOO_RS08950
uniprot id: A0A097IH22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS12650
gene id: 558173:CDOO_RS12650
uniprot id: A0A097IIV1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS05800
gene id: 558173:CDOO_RS05800
uniprot id: A0A097IFE8
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07245
gene id: 558173:CDOO_RS07245
uniprot id: A0A097IG51
names: Similarity
messages: Belongs to the band 7/mec-2 family.

558173:CDOO RS06475
gene id: 558173:CDOO_RS06475
uniprot id: A0A097IFQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

558173:CDOO RS05245
gene id: 558173:CDOO_RS05245
uniprot id: A0A097IF53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

558173:CDOO RS03195
gene id: 558173:CDOO_RS03195
uniprot id: A0A097IE16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

558173:CDOO RS10195
gene id: 558173:CDOO_RS10195
uniprot id: A0A097IHN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS06535
gene id: 558173:CDOO_RS06535
uniprot id: A0A097IFT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS02840
gene id: 558173:CDOO_RS02840
uniprot id: A0A097IDX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

558173:CDOO RS04565
gene id: 558173:CDOO_RS04565
uniprot id: A0A097IES7
names: Similarity
messages: Belongs to the EfeM/EfeO family.

558173:CDOO RS07625
gene id: 558173:CDOO_RS07625
uniprot id: A0A097IGD1
names: Similarity
messages: Belongs to the peptidase A24 family.

558173:CDOO RS11490
gene id: 558173:CDOO_RS11490
uniprot id: A0A097II95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

558173:CDOO RS02250
gene id: 558173:CDOO_RS02250
uniprot id: A0A097IDN0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

558173:CDOO RS06660
gene id: 558173:CDOO_RS06660
uniprot id: A0A097IFU5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

558173:CDOO RS01495
gene id: 558173:CDOO_RS01495
uniprot id: A0A097IDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS03265
gene id: 558173:CDOO_RS03265
uniprot id: A0A097IE46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS06215
gene id: 558173:CDOO_RS06215
uniprot id: A0A097IFK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS02900
gene id: 558173:CDOO_RS02900
uniprot id: A0A097IDY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

558173:CDOO RS02705
gene id: 558173:CDOO_RS02705
uniprot id: A0A097IDT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

558173:CDOO RS09470
gene id: 558173:CDOO_RS09470
uniprot id: A0A097IH99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

558173:CDOO RS03115
gene id: 558173:CDOO_RS03115
uniprot id: A0A097IE18
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS04120
gene id: 558173:CDOO_RS04120
uniprot id: A0A097IEJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

558173:CDOO RS07355
gene id: 558173:CDOO_RS07355
uniprot id: A0A097IG60
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

558173:CDOO RS03935
gene id: 558173:CDOO_RS03935
uniprot id: A0A097IEF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS12390
gene id: 558173:CDOO_RS12390
uniprot id: A0A097IIS8
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

558173:CDOO RS00380
gene id: 558173:CDOO_RS00380
uniprot id: A0A097ICW3
names: Similarity
messages: Belongs to the CmpA/NrtA family.

558173:CDOO RS06740
gene id: 558173:CDOO_RS06740
uniprot id: A0A097IFV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS06690
gene id: 558173:CDOO_RS06690
uniprot id: A0A097IFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

558173:CDOO RS10415
gene id: 558173:CDOO_RS10415
uniprot id: A0A097IHS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

558173:CDOO RS04685
gene id: 558173:CDOO_RS04685
uniprot id: A0A097IES9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS10820
gene id: 558173:CDOO_RS10820
uniprot id: A0A097IHZ2
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

558173:CDOO RS06195
gene id: 558173:CDOO_RS06195
uniprot id: A0A097IFL2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

558173:CDOO RS08735
gene id: 558173:CDOO_RS08735
uniprot id: A0A097IGW4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

558173:CDOO RS02450
gene id: 558173:CDOO_RS02450
uniprot id: A0A097IDQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

558173:CDOO RS12765
gene id: 558173:CDOO_RS12765
uniprot id: A0A097IIX3
names: Similarity
messages: Belongs to the FPG family.

558173:CDOO RS06435
gene id: 558173:CDOO_RS06435
uniprot id: A0A097IFQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS11235
gene id: 558173:CDOO_RS11235
uniprot id: A0A097II69
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

558173:CDOO RS10205
gene id: 558173:CDOO_RS10205
uniprot id: A0A097IHN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

558173:CDOO RS11900
gene id: 558173:CDOO_RS11900
uniprot id: A0A097IIG6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

558173:CDOO RS00025
gene id: 558173:CDOO_RS00025
uniprot id: A0A097ICP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

558173:CDOO RS03770
gene id: 558173:CDOO_RS03770
uniprot id: A0A097IED8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

558173:CDOO RS07760
gene id: 558173:CDOO_RS07760
uniprot id: A0A097IGE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS05880
gene id: 558173:CDOO_RS05880
uniprot id: A0A097IFG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

558173:CDOO RS03460
gene id: 558173:CDOO_RS03460
uniprot id: A0A097IE98
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

558173:CDOO RS04100
gene id: 558173:CDOO_RS04100
uniprot id: A0A097IEI0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

558173:CDOO RS11825
gene id: 558173:CDOO_RS11825
uniprot id: A0A097IIH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

558173:CDOO RS03095
gene id: 558173:CDOO_RS03095
uniprot id: A0A097IDZ7
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

558173:CDOO RS05910
gene id: 558173:CDOO_RS05910
uniprot id: A0A097IFI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

558173:CDOO RS09370
gene id: 558173:CDOO_RS09370
uniprot id: A0A097IH87
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

558173:CDOO RS01375
gene id: 558173:CDOO_RS01375
uniprot id: A0A097ID98
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

558173:CDOO RS12655
gene id: 558173:CDOO_RS12655
uniprot id: A0A097IIU6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

558173:CDOO RS09180
gene id: 558173:CDOO_RS09180
uniprot id: A0A097IH39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

558173:CDOO RS09125
gene id: 558173:CDOO_RS09125
uniprot id: A0A097IH66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

558173:CDOO RS07620
gene id: 558173:CDOO_RS07620
uniprot id: A0A097IGA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

558173:CDOO RS13010
gene id: 558173:CDOO_RS13010
uniprot id: A0A097IJR6
names: Similarity
messages: Belongs to the HsdR family.

558173:CDOO RS09655
gene id: 558173:CDOO_RS09655
uniprot id: A0A097IHD3
names: Similarity
messages: Belongs to the Dps family.

558173:CDOO RS05785
gene id: 558173:CDOO_RS05785
uniprot id: A0A097IFC7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

558173:CDOO RS03630
gene id: 558173:CDOO_RS03630
uniprot id: A0A097IEA4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

558173:CDOO RS00415
gene id: 558173:CDOO_RS00415
uniprot id: A0A097ICW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

558173:CDOO RS07420
gene id: 558173:CDOO_RS07420
uniprot id: A0A097IG67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

558173:CDOO RS10060
gene id: 558173:CDOO_RS10060
uniprot id: A0A097IHL0
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS12075
gene id: 558173:CDOO_RS12075
uniprot id: A0A097IIL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

558173:CDOO RS02885
gene id: 558173:CDOO_RS02885
uniprot id: A0A097IDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

558173:CDOO RS02350
gene id: 558173:CDOO_RS02350
uniprot id: A0A097IDP6
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS09005
gene id: 558173:CDOO_RS09005
uniprot id: A0A097IH13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

558173:CDOO RS08250
gene id: 558173:CDOO_RS08250
uniprot id: A0A097IGM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

558173:CDOO RS09000
gene id: 558173:CDOO_RS09000
uniprot id: A0A097IH33
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

558173:CDOO RS00890
gene id: 558173:CDOO_RS00890
uniprot id: A0A097ID27
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

558173:CDOO RS02650
gene id: 558173:CDOO_RS02650
uniprot id: A0A097IDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

558173:CDOO RS03515
gene id: 558173:CDOO_RS03515
uniprot id: A0A097IEA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

558173:CDOO RS12870
gene id: 558173:CDOO_RS12870
uniprot id: A0A097IIZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

558173:CDOO RS00375
gene id: 558173:CDOO_RS00375
uniprot id: A0A097ICU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS01570
gene id: 558173:CDOO_RS01570
uniprot id: A0A097IDC3
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS11595
gene id: 558173:CDOO_RS11595
uniprot id: A0A097IIB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

558173:CDOO RS05875
gene id: 558173:CDOO_RS05875
uniprot id: A0A097IFF9
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS05825
gene id: 558173:CDOO_RS05825
uniprot id: A0A097IFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

558173:CDOO RS02645
gene id: 558173:CDOO_RS02645
uniprot id: A0A097IDS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

558173:CDOO RS04505
gene id: 558173:CDOO_RS04505
uniprot id: A0A097IEQ2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06170
gene id: 558173:CDOO_RS06170
uniprot id: A0A097IFK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

558173:CDOO RS12960
gene id: 558173:CDOO_RS12960
uniprot id: A0A097IJ01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

558173:CDOO RS05535
gene id: 558173:CDOO_RS05535
uniprot id: A0A097IF95
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

558173:CDOO RS02895
gene id: 558173:CDOO_RS02895
uniprot id: A0A097IDW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

558173:CDOO RS06390
gene id: 558173:CDOO_RS06390
uniprot id: A0A097IFP4
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

558173:CDOO RS08680
gene id: 558173:CDOO_RS08680
uniprot id: A0A097IGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

558173:CDOO RS14320
gene id: 558173:CDOO_RS14320
uniprot id: A0A097IG89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

558173:CDOO RS04045
gene id: 558173:CDOO_RS04045
uniprot id: A0A097IEH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

558173:CDOO RS05150
gene id: 558173:CDOO_RS05150
uniprot id: A0A097IF33
names: Similarity
messages: Belongs to the TPP enzyme family.

558173:CDOO RS07140
gene id: 558173:CDOO_RS07140
uniprot id: A0A097IG28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

558173:CDOO RS04150
gene id: 558173:CDOO_RS04150
uniprot id: A0A097IEM0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

558173:CDOO RS05715
gene id: 558173:CDOO_RS05715
uniprot id: A0A097IFC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

558173:CDOO RS07415
gene id: 558173:CDOO_RS07415
uniprot id: A0A097IGA5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

558173:CDOO RS02865
gene id: 558173:CDOO_RS02865
uniprot id: A0A097IDY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

558173:CDOO RS08925
gene id: 558173:CDOO_RS08925
uniprot id: A0A097IH16
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

558173:CDOO RS06725
gene id: 558173:CDOO_RS06725
uniprot id: A0A097IFV5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

558173:CDOO RS02845
gene id: 558173:CDOO_RS02845
uniprot id: A0A097IDV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

558173:CDOO RS03320
gene id: 558173:CDOO_RS03320
uniprot id: A0A097IE57
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

558173:CDOO RS09150
gene id: 558173:CDOO_RS09150
uniprot id: A0A097IH69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

558173:CDOO RS04125
gene id: 558173:CDOO_RS04125
uniprot id: A0A097IEJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

558173:CDOO RS02355
gene id: 558173:CDOO_RS02355
uniprot id: A0A097IDQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

558173:CDOO RS02910
gene id: 558173:CDOO_RS02910
uniprot id: A0A097IDY2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

558173:CDOO RS11430
gene id: 558173:CDOO_RS11430
uniprot id: A0A097II91
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS07590
gene id: 558173:CDOO_RS07590
uniprot id: A0A097IGE0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

558173:CDOO RS04785
gene id: 558173:CDOO_RS04785
uniprot id: A0A097IEW7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

558173:CDOO RS02770
gene id: 558173:CDOO_RS02770
uniprot id: A0A097IDT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

558173:CDOO RS03030
gene id: 558173:CDOO_RS03030
uniprot id: A0A097IDY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

558173:CDOO RS02850
gene id: 558173:CDOO_RS02850
uniprot id: A0A097IDX1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

558173:CDOO RS12515
gene id: 558173:CDOO_RS12515
uniprot id: A0A097IIS5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

558173:CDOO RS04455
gene id: 558173:CDOO_RS04455
uniprot id: A0A097IEP1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS00880
gene id: 558173:CDOO_RS00880
uniprot id: A0A097ID19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS04040
gene id: 558173:CDOO_RS04040
uniprot id: A0A097IEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

558173:CDOO RS06625
gene id: 558173:CDOO_RS06625
uniprot id: A0A097IFT2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06710
gene id: 558173:CDOO_RS06710
uniprot id: A0A097IFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

558173:CDOO RS07215
gene id: 558173:CDOO_RS07215
uniprot id: A0A097IG46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

558173:CDOO RS07225
gene id: 558173:CDOO_RS07225
uniprot id: A0A097IG42
names: Similarity
messages: Belongs to the UPF0098 family.

558173:CDOO RS04205
gene id: 558173:CDOO_RS04205
uniprot id: A0A097IEK8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

558173:CDOO RS08980
gene id: 558173:CDOO_RS08980
uniprot id: A0A097IH10
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

558173:CDOO RS03815
gene id: 558173:CDOO_RS03815
uniprot id: A0A097IEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

558173:CDOO RS08965
gene id: 558173:CDOO_RS08965
uniprot id: A0A097IH38
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS01445
gene id: 558173:CDOO_RS01445
uniprot id: A0A097IDA5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS07130
gene id: 558173:CDOO_RS07130
uniprot id: A0A097IG53
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

558173:CDOO RS08995
gene id: 558173:CDOO_RS08995
uniprot id: A0A097IGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

558173:CDOO RS00100
gene id: 558173:CDOO_RS00100
uniprot id: A0A097ICP6
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS09270
gene id: 558173:CDOO_RS09270
uniprot id: A0A097IH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

558173:CDOO RS07135
gene id: 558173:CDOO_RS07135
uniprot id: A0A097IG16
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

558173:CDOO RS08600
gene id: 558173:CDOO_RS08600
uniprot id: A0A097IGS5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

558173:CDOO RS08225
gene id: 558173:CDOO_RS08225
uniprot id: A0A097IGK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS10015
gene id: 558173:CDOO_RS10015
uniprot id: A0A097IHI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

558173:CDOO RS02200
gene id: 558173:CDOO_RS02200
uniprot id: A0A097IDL9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

558173:CDOO RS03955
gene id: 558173:CDOO_RS03955
uniprot id: A0A097IEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

558173:CDOO RS04755
gene id: 558173:CDOO_RS04755
uniprot id: A0A097IEW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

558173:CDOO RS02525
gene id: 558173:CDOO_RS02525
uniprot id: A0A097IDQ0
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS09250
gene id: 558173:CDOO_RS09250
uniprot id: A0A097IH74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

558173:CDOO RS09485
gene id: 558173:CDOO_RS09485
uniprot id: A0A097IJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

558173:CDOO RS04465
gene id: 558173:CDOO_RS04465
uniprot id: A0A097IES3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

558173:CDOO RS09475
gene id: 558173:CDOO_RS09475
uniprot id: A0A097IHA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

558173:CDOO RS11110
gene id: 558173:CDOO_RS11110
uniprot id: A0A097II31
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

558173:CDOO RS09990
gene id: 558173:CDOO_RS09990
uniprot id: A0A097IHH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

558173:CDOO RS11470
gene id: 558173:CDOO_RS11470
uniprot id: A0A097IIA7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

558173:CDOO RS08880
gene id: 558173:CDOO_RS08880
uniprot id: A0A097IGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

558173:CDOO RS11375
gene id: 558173:CDOO_RS11375
uniprot id: A0A097II73
names: Similarity
messages: Belongs to the Nth/MutY family.

558173:CDOO RS05465
gene id: 558173:CDOO_RS05465
uniprot id: A0A097IF99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

558173:CDOO RS08515
gene id: 558173:CDOO_RS08515
uniprot id: A0A097IGQ9
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS04375
gene id: 558173:CDOO_RS04375
uniprot id: A0A097IEM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

558173:CDOO RS08380
gene id: 558173:CDOO_RS08380
uniprot id: A0A097IGR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

558173:CDOO RS05490
gene id: 558173:CDOO_RS05490
uniprot id: A0A097IFA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

558173:CDOO RS12855
gene id: 558173:CDOO_RS12855
uniprot id: A0A097IIY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS03380
gene id: 558173:CDOO_RS03380
uniprot id: A0A097IE64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

558173:CDOO RS05330
gene id: 558173:CDOO_RS05330
uniprot id: A0A097IF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS05780
gene id: 558173:CDOO_RS05780
uniprot id: A0A097IFF6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS06810
gene id: 558173:CDOO_RS06810
uniprot id: A0A097IFW3
names: Similarity
messages: Belongs to the TlyA family.

558173:CDOO RS07480
gene id: 558173:CDOO_RS07480
uniprot id: A0A097IG88
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

558173:CDOO RS12630
gene id: 558173:CDOO_RS12630
uniprot id: A0A097IIU2
names: Similarity
messages: Belongs to the PspA/IM30 family.

558173:CDOO RS04430
gene id: 558173:CDOO_RS04430
uniprot id: A0A097IEN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS01235
gene id: 558173:CDOO_RS01235
uniprot id: A0A097ID70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

558173:CDOO RS02745
gene id: 558173:CDOO_RS02745
uniprot id: A0A097IDV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

558173:CDOO RS05370
gene id: 558173:CDOO_RS05370
uniprot id: A0A097IF78
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

558173:CDOO RS07490
gene id: 558173:CDOO_RS07490
uniprot id: A0A097IGB9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

558173:CDOO RS00325
gene id: 558173:CDOO_RS00325
uniprot id: A0A097ICT4
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07515
gene id: 558173:CDOO_RS07515
uniprot id: A0A097IGC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS01470
gene id: 558173:CDOO_RS01470
uniprot id: A0A097ID97
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

558173:CDOO RS12845
gene id: 558173:CDOO_RS12845
uniprot id: A0A097IIZ2
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

558173:CDOO RS14325
gene id: 558173:CDOO_RS14325
uniprot id: A0A097IG76
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

558173:CDOO RS09890
gene id: 558173:CDOO_RS09890
uniprot id: A0A097IHF7
names: Similarity
messages: Belongs to the Fur family.

558173:CDOO RS12595
gene id: 558173:CDOO_RS12595
uniprot id: A0A097IIT9
names: Similarity
messages: Belongs to the universal stress protein A family.

558173:CDOO RS03155
gene id: 558173:CDOO_RS03155
uniprot id: A0A097IE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS12925
gene id: 558173:CDOO_RS12925
uniprot id: A0A097IJ05
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

558173:CDOO RS04405
gene id: 558173:CDOO_RS04405
uniprot id: A0A097IEP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

558173:CDOO RS06780
gene id: 558173:CDOO_RS06780
uniprot id: A0A097IFW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS02715
gene id: 558173:CDOO_RS02715
uniprot id: A0A097IDS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

558173:CDOO RS08725
gene id: 558173:CDOO_RS08725
uniprot id: A0A097IGT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

558173:CDOO RS05815
gene id: 558173:CDOO_RS05815
uniprot id: A0A097IFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

558173:CDOO RS02870
gene id: 558173:CDOO_RS02870
uniprot id: A0A097IDW3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

558173:CDOO RS06245
gene id: 558173:CDOO_RS06245
uniprot id: A0A097IFM3
names: Similarity
messages: Belongs to the isochorismate synthase family.

558173:CDOO RS06200
gene id: 558173:CDOO_RS06200
uniprot id: A0A097IFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

558173:CDOO RS09230
gene id: 558173:CDOO_RS09230
uniprot id: A0A097IH51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS04300
gene id: 558173:CDOO_RS04300
uniprot id: A0A097IEL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

558173:CDOO RS02110
gene id: 558173:CDOO_RS02110
uniprot id: A0A097IDJ0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

558173:CDOO RS05135
gene id: 558173:CDOO_RS05135
uniprot id: A0A097IF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

558173:CDOO RS08825
gene id: 558173:CDOO_RS08825
uniprot id: A0A097IGX0
names: Similarity
messages: Belongs to the acylphosphatase family.

558173:CDOO RS00650
gene id: 558173:CDOO_RS00650
uniprot id: A0A097ICZ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

558173:CDOO RS04330
gene id: 558173:CDOO_RS04330
uniprot id: A0A097IEN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

558173:CDOO RS12900
gene id: 558173:CDOO_RS12900
uniprot id: A0A097IIZ9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

558173:CDOO RS07660
gene id: 558173:CDOO_RS07660
uniprot id: A0A097IGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS09930
gene id: 558173:CDOO_RS09930
uniprot id: A0A097IHI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

558173:CDOO RS12775
gene id: 558173:CDOO_RS12775
uniprot id: A0A097IIW8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

558173:CDOO RS11485
gene id: 558173:CDOO_RS11485
uniprot id: A0A097II93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

558173:CDOO RS08230
gene id: 558173:CDOO_RS08230
uniprot id: A0A097IGQ0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

558173:CDOO RS02265
gene id: 558173:CDOO_RS02265
uniprot id: A0A097IDK7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

558173:CDOO RS12025
gene id: 558173:CDOO_RS12025
uniprot id: A0A097IIK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

558173:CDOO RS08420
gene id: 558173:CDOO_RS08420
uniprot id: A0A097IGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

558173:CDOO RS03290
gene id: 558173:CDOO_RS03290
uniprot id: A0A097IE51
names: Similarity
messages: Belongs to the peptidase C40 family.

558173:CDOO RS09255
gene id: 558173:CDOO_RS09255
uniprot id: A0A097IH52
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS02465
gene id: 558173:CDOO_RS02465
uniprot id: A0A097IDS2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

558173:CDOO RS10235
gene id: 558173:CDOO_RS10235
uniprot id: A0A097IHL7
names: Similarity
messages: Belongs to the pirin family.

558173:CDOO RS09960
gene id: 558173:CDOO_RS09960
uniprot id: A0A097IHI3
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10180
gene id: 558173:CDOO_RS10180
uniprot id: A0A097IHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

558173:CDOO RS05310
gene id: 558173:CDOO_RS05310
uniprot id: A0A097IF39
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10380
gene id: 558173:CDOO_RS10380
uniprot id: A0A097IHS0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

558173:CDOO RS11645
gene id: 558173:CDOO_RS11645
uniprot id: A0A097IIC2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

558173:CDOO RS08955
gene id: 558173:CDOO_RS08955
uniprot id: A0A097IH04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

558173:CDOO RS09075
gene id: 558173:CDOO_RS09075
uniprot id: A0A097IGZ1
names: Similarity
messages: Belongs to the IMPACT family.

558173:CDOO RS06815
gene id: 558173:CDOO_RS06815
uniprot id: A0A097IFW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS04745
gene id: 558173:CDOO_RS04745
uniprot id: A0A097IEW1
names: Similarity
messages: Belongs to the FBPase class 2 family.

558173:CDOO RS03545
gene id: 558173:CDOO_RS03545
uniprot id: A0A097IE90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

558173:CDOO RS07435
gene id: 558173:CDOO_RS07435
uniprot id: A0A097IG83
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

558173:CDOO RS11610
gene id: 558173:CDOO_RS11610
uniprot id: A0A097IIB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

558173:CDOO RS03500
gene id: 558173:CDOO_RS03500
uniprot id: A0A097IE76
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

558173:CDOO RS12835
gene id: 558173:CDOO_RS12835
uniprot id: A0A097IIX7
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS05690
gene id: 558173:CDOO_RS05690
uniprot id: A0A097IFC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

558173:CDOO RS10730
gene id: 558173:CDOO_RS10730
uniprot id: A0A097IHX4
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06145
gene id: 558173:CDOO_RS06145
uniprot id: A0A097IFK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS04115
gene id: 558173:CDOO_RS04115
uniprot id: A0A097IEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

558173:CDOO RS07175
gene id: 558173:CDOO_RS07175
uniprot id: A0A097IG32
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

558173:CDOO RS03890
gene id: 558173:CDOO_RS03890
uniprot id: A0A097IEE9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

558173:CDOO RS03250
gene id: 558173:CDOO_RS03250
uniprot id: A0A097IE43
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

558173:CDOO RS03325
gene id: 558173:CDOO_RS03325
uniprot id: A0A097IE41
names: Similarity
messages: Belongs to the PrpD family.

558173:CDOO RS07465
gene id: 558173:CDOO_RS07465
uniprot id: A0A097IGB4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

558173:CDOO RS10795
gene id: 558173:CDOO_RS10795
uniprot id: A0A097IHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

558173:CDOO RS10995
gene id: 558173:CDOO_RS10995
uniprot id: A0A097II13
names: Similarity
messages: Belongs to the CsoR family.

558173:CDOO RS04290
gene id: 558173:CDOO_RS04290
uniprot id: A0A097IEM4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

558173:CDOO RS08705
gene id: 558173:CDOO_RS08705
uniprot id: A0A097IGX7
names: Similarity
messages: Belongs to the DprA/Smf family.

558173:CDOO RS06895
gene id: 558173:CDOO_RS06895
uniprot id: A0A097IFX7
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS02695
gene id: 558173:CDOO_RS02695
uniprot id: A0A097IDU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

558173:CDOO RS09315
gene id: 558173:CDOO_RS09315
uniprot id: A0A097IH63
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

558173:CDOO RS08550
gene id: 558173:CDOO_RS08550
uniprot id: A0A097IGQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

558173:CDOO RS07705
gene id: 558173:CDOO_RS07705
uniprot id: A0A097IGD7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

558173:CDOO RS07880
gene id: 558173:CDOO_RS07880
uniprot id: A0A097IGF9
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

558173:CDOO RS04535
gene id: 558173:CDOO_RS04535
uniprot id: A0A097IES2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

558173:CDOO RS02690
gene id: 558173:CDOO_RS02690
uniprot id: A0A097IDS1
names: Similarity
messages: Belongs to the asp23 family.

558173:CDOO RS11500
gene id: 558173:CDOO_RS11500
uniprot id: A0A097II99
names: Similarity
messages: Belongs to the peptidase S13 family.

558173:CDOO RS07000
gene id: 558173:CDOO_RS07000
uniprot id: A0A097IG01
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

558173:CDOO RS08215
gene id: 558173:CDOO_RS08215
uniprot id: A0A097IGN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS02725
gene id: 558173:CDOO_RS02725
uniprot id: A0A097IDV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

558173:CDOO RS12330
gene id: 558173:CDOO_RS12330
uniprot id: A0A097IIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS09110
gene id: 558173:CDOO_RS09110
uniprot id: A0A097IH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

558173:CDOO RS01605
gene id: 558173:CDOO_RS01605
uniprot id: A0A097IDC0
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS02055
gene id: 558173:CDOO_RS02055
uniprot id: A0A097IDJ4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

558173:CDOO RS09650
gene id: 558173:CDOO_RS09650
uniprot id: A0A097IHF2
names: Similarity
messages: Belongs to the AHA1 family.

558173:CDOO RS09745
gene id: 558173:CDOO_RS09745
uniprot id: A0A097IHE9
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10830
gene id: 558173:CDOO_RS10830
uniprot id: A0A097IHX8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

558173:CDOO RS10305
gene id: 558173:CDOO_RS10305
uniprot id: A0A097IHQ3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

558173:CDOO RS02765
gene id: 558173:CDOO_RS02765
uniprot id: A0A097IDV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

558173:CDOO RS10475
gene id: 558173:CDOO_RS10475
uniprot id: A0A097IHT2
names: Similarity
messages: Belongs to the peptidase M1 family.

558173:CDOO RS08425
gene id: 558173:CDOO_RS08425
uniprot id: A0A097IGN1
names: Similarity
messages: Belongs to the YciI family.

558173:CDOO RS02890
gene id: 558173:CDOO_RS02890
uniprot id: A0A097IDY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

558173:CDOO RS03405
gene id: 558173:CDOO_RS03405
uniprot id: A0A097IE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS07545
gene id: 558173:CDOO_RS07545
uniprot id: A0A097IG91
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS02730
gene id: 558173:CDOO_RS02730
uniprot id: A0A097IDU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

558173:CDOO RS05685
gene id: 558173:CDOO_RS05685
uniprot id: A0A097IFB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

558173:CDOO RS02095
gene id: 558173:CDOO_RS02095
uniprot id: A0A097IDH7
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

558173:CDOO RS07665
gene id: 558173:CDOO_RS07665
uniprot id: A0A097IGF7
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS12980
gene id: 558173:CDOO_RS12980
uniprot id: A0A097IJ07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

558173:CDOO RS02535
gene id: 558173:CDOO_RS02535
uniprot id: A0A097IDT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

558173:CDOO RS12720
gene id: 558173:CDOO_RS12720
uniprot id: A0A097IIY7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

558173:CDOO RS06140
gene id: 558173:CDOO_RS06140
uniprot id: A0A097IFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

558173:CDOO RS02515
gene id: 558173:CDOO_RS02515
uniprot id: A0A097IDR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

558173:CDOO RS00430
gene id: 558173:CDOO_RS00430
uniprot id: A0A097ICU7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

558173:CDOO RS02835
gene id: 558173:CDOO_RS02835
uniprot id: A0A097IDW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

558173:CDOO RS10890
gene id: 558173:CDOO_RS10890
uniprot id: A0A097II12
names: Similarity
messages: Belongs to the phosphohexose mutase family.

558173:CDOO RS12510
gene id: 558173:CDOO_RS12510
uniprot id: A0A097IIS2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

558173:CDOO RS11685
gene id: 558173:CDOO_RS11685
uniprot id: A0A097IID5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

558173:CDOO RS07950
gene id: 558173:CDOO_RS07950
uniprot id: A0A097IGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

558173:CDOO RS10460
gene id: 558173:CDOO_RS10460
uniprot id: A0A097IHQ9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

558173:CDOO RS04495
gene id: 558173:CDOO_RS04495
uniprot id: A0A097IER5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

558173:CDOO RS00485
gene id: 558173:CDOO_RS00485
uniprot id: A0A097ICX8
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

558173:CDOO RS00770
gene id: 558173:CDOO_RS00770
uniprot id: A0A097ID06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS06500
gene id: 558173:CDOO_RS06500
uniprot id: A0A097IFR3
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

558173:CDOO RS10755
gene id: 558173:CDOO_RS10755
uniprot id: A0A097IHW2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

558173:CDOO RS07165
gene id: 558173:CDOO_RS07165
uniprot id: A0A097IG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

558173:CDOO RS00670
gene id: 558173:CDOO_RS00670
uniprot id: A0A097ICZ8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

558173:CDOO RS12930
gene id: 558173:CDOO_RS12930
uniprot id: A0A097IIZ8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

558173:CDOO RS10065
gene id: 558173:CDOO_RS10065
uniprot id: A0A097IHK5
names: Similarity
messages: Belongs to the peptidase S33 family.

558173:CDOO RS06470
gene id: 558173:CDOO_RS06470
uniprot id: A0A097IFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

558173:CDOO RS08690
gene id: 558173:CDOO_RS08690
uniprot id: A0A097IGU3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

558173:CDOO RS10530
gene id: 558173:CDOO_RS10530
uniprot id: A0A097IHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS07805
gene id: 558173:CDOO_RS07805
uniprot id: A0A097IGH0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

558173:CDOO RS08875
gene id: 558173:CDOO_RS08875
uniprot id: A0A097IGY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

558173:CDOO RS00055
gene id: 558173:CDOO_RS00055
uniprot id: A0A097ICN0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

558173:CDOO RS03165
gene id: 558173:CDOO_RS03165
uniprot id: A0A097IE26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

558173:CDOO RS09940
gene id: 558173:CDOO_RS09940
uniprot id: A0A097IHG6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

558173:CDOO RS04445
gene id: 558173:CDOO_RS04445
uniprot id: A0A097IEQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

558173:CDOO RS05410
gene id: 558173:CDOO_RS05410
uniprot id: A0A097IF82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

558173:CDOO RS08370
gene id: 558173:CDOO_RS08370
uniprot id: A0A097IGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS04350
gene id: 558173:CDOO_RS04350
uniprot id: A0A097IEM3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

558173:CDOO RS05720
gene id: 558173:CDOO_RS05720
uniprot id: A0A097IFD4
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06445
gene id: 558173:CDOO_RS06445
uniprot id: A0A097IFP6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

558173:CDOO RS11505
gene id: 558173:CDOO_RS11505
uniprot id: A0A097IIA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

558173:CDOO RS09575
gene id: 558173:CDOO_RS09575
uniprot id: A0A097IHB7
names: Similarity
messages: Belongs to the glutamine synthetase family.

558173:CDOO RS12255
gene id: 558173:CDOO_RS12255
uniprot id: A0A097IIM1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS09215
gene id: 558173:CDOO_RS09215
uniprot id: A0A097IH14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

558173:CDOO RS12935
gene id: 558173:CDOO_RS12935
uniprot id: A0A097IIZ5
names: Similarity
messages: Belongs to the thioredoxin family.

558173:CDOO RS02045
gene id: 558173:CDOO_RS02045
uniprot id: A0A097IDG5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

558173:CDOO RS09545
gene id: 558173:CDOO_RS09545
uniprot id: A0A097IHD4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

558173:CDOO RS11445
gene id: 558173:CDOO_RS11445
uniprot id: A0A097IIA3
names: Similarity
messages: Belongs to the pantothenate synthetase family.

558173:CDOO RS09365
gene id: 558173:CDOO_RS09365
uniprot id: A0A097IH71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

558173:CDOO RS03995
gene id: 558173:CDOO_RS03995
uniprot id: A0A097IEG5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

558173:CDOO RS07155
gene id: 558173:CDOO_RS07155
uniprot id: A0A097IG57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

558173:CDOO RS06005
gene id: 558173:CDOO_RS06005
uniprot id: A0A097IFG8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

558173:CDOO RS07180
gene id: 558173:CDOO_RS07180
uniprot id: A0A097IG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

558173:CDOO RS04760
gene id: 558173:CDOO_RS04760
uniprot id: A0A097IEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

558173:CDOO RS07345
gene id: 558173:CDOO_RS07345
uniprot id: A0A097IG54
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

558173:CDOO RS03065
gene id: 558173:CDOO_RS03065
uniprot id: A0A097IE08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

558173:CDOO RS09455
gene id: 558173:CDOO_RS09455
uniprot id: A0A097IH94
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

558173:CDOO RS00180
gene id: 558173:CDOO_RS00180
uniprot id: A0A097ICR0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

558173:CDOO RS01285
gene id: 558173:CDOO_RS01285
uniprot id: A0A097ID86
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

558173:CDOO RS04560
gene id: 558173:CDOO_RS04560
uniprot id: A0A097IET6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

558173:CDOO RS11075
gene id: 558173:CDOO_RS11075
uniprot id: A0A097II25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

558173:CDOO RS10715
gene id: 558173:CDOO_RS10715
uniprot id: A0A097IHX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

558173:CDOO RS00540
gene id: 558173:CDOO_RS00540
uniprot id: A0A097ICW2
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

558173:CDOO RS00565
gene id: 558173:CDOO_RS00565
uniprot id: A0A097ICW4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

558173:CDOO RS11730
gene id: 558173:CDOO_RS11730
uniprot id: A0A097IID7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

558173:CDOO RS07810
gene id: 558173:CDOO_RS07810
uniprot id: A0A097IGF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

558173:CDOO RS07675
gene id: 558173:CDOO_RS07675
uniprot id: A0A097IGE3
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS03060
gene id: 558173:CDOO_RS03060
uniprot id: A0A097IDZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

558173:CDOO RS12155
gene id: 558173:CDOO_RS12155
uniprot id: A0A097IIL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

558173:CDOO RS04630
gene id: 558173:CDOO_RS04630
uniprot id: A0A097IET7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS00125
gene id: 558173:CDOO_RS00125
uniprot id: A0A097ICQ0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

558173:CDOO RS09935
gene id: 558173:CDOO_RS09935
uniprot id: A0A097IHH8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

558173:CDOO RS07790
gene id: 558173:CDOO_RS07790
uniprot id: A0A097IGE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

558173:CDOO RS10200
gene id: 558173:CDOO_RS10200
uniprot id: A0A097IHN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

558173:CDOO RS04365
gene id: 558173:CDOO_RS04365
uniprot id: A0A097IEP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

558173:CDOO RS09645
gene id: 558173:CDOO_RS09645
uniprot id: A0A097IHC1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

558173:CDOO RS11290
gene id: 558173:CDOO_RS11290
uniprot id: A0A097II79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

558173:CDOO RS05885
gene id: 558173:CDOO_RS05885
uniprot id: A0A097IFH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

558173:CDOO RS08710
gene id: 558173:CDOO_RS08710
uniprot id: A0A097IGW0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

558173:CDOO RS02050
gene id: 558173:CDOO_RS02050
uniprot id: A0A097IDJ3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

558173:CDOO RS05700
gene id: 558173:CDOO_RS05700
uniprot id: A0A097IFE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

558173:CDOO RS10955
gene id: 558173:CDOO_RS10955
uniprot id: A0A097II24
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

558173:CDOO RS06885
gene id: 558173:CDOO_RS06885
uniprot id: A0A097IFX6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

558173:CDOO RS05275
gene id: 558173:CDOO_RS05275
uniprot id: A0A097IF60
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS02640
gene id: 558173:CDOO_RS02640
uniprot id: A0A097IDU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

558173:CDOO RS09895
gene id: 558173:CDOO_RS09895
uniprot id: A0A097IHI8
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06840
gene id: 558173:CDOO_RS06840
uniprot id: A0A097IFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

558173:CDOO RS03235
gene id: 558173:CDOO_RS03235
uniprot id: A0A097IE24
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

558173:CDOO RS11265
gene id: 558173:CDOO_RS11265
uniprot id: A0A097II56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS10805
gene id: 558173:CDOO_RS10805
uniprot id: A0A097IHX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

558173:CDOO RS01360
gene id: 558173:CDOO_RS01360
uniprot id: A0A097IDA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

558173:CDOO RS12300
gene id: 558173:CDOO_RS12300
uniprot id: A0A097IIP3
names: Similarity
messages: Belongs to the AccD/PCCB family.

558173:CDOO RS07455
gene id: 558173:CDOO_RS07455
uniprot id: A0A097IG81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

558173:CDOO RS11305
gene id: 558173:CDOO_RS11305
uniprot id: A0A097II75
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

558173:CDOO RS06520
gene id: 558173:CDOO_RS06520
uniprot id: A0A097IFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS12245
gene id: 558173:CDOO_RS12245
uniprot id: A0A097IIM5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

558173:CDOO RS07755
gene id: 558173:CDOO_RS07755
uniprot id: A0A097IGG1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

558173:CDOO RS10850
gene id: 558173:CDOO_RS10850
uniprot id: A0A097II07
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS12085
gene id: 558173:CDOO_RS12085
uniprot id: A0A097IIK8
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

558173:CDOO RS09245
gene id: 558173:CDOO_RS09245
uniprot id: A0A097IH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

558173:CDOO RS04880
gene id: 558173:CDOO_RS04880
uniprot id: A0A097IEZ0
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

558173:CDOO RS05325
gene id: 558173:CDOO_RS05325
uniprot id: A0A097IF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS08525
gene id: 558173:CDOO_RS08525
uniprot id: A0A097IGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

558173:CDOO RS11320
gene id: 558173:CDOO_RS11320
uniprot id: A0A097II65
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

558173:CDOO RS02970
gene id: 558173:CDOO_RS02970
uniprot id: A0A097IDZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

558173:CDOO RS01365
gene id: 558173:CDOO_RS01365
uniprot id: A0A097ID99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

558173:CDOO RS02855
gene id: 558173:CDOO_RS02855
uniprot id: A0A097IDV2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

558173:CDOO RS09355
gene id: 558173:CDOO_RS09355
uniprot id: A0A097IH83
names: Similarity
messages: Belongs to the peptidase C40 family.

558173:CDOO RS09240
gene id: 558173:CDOO_RS09240
uniprot id: A0A097IH78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

558173:CDOO RS10635
gene id: 558173:CDOO_RS10635
uniprot id: A0A097IHV8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

558173:CDOO RS06485
gene id: 558173:CDOO_RS06485
uniprot id: A0A097IFR7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

558173:CDOO RS09385
gene id: 558173:CDOO_RS09385
uniprot id: A0A097IH73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

558173:CDOO RS06490
gene id: 558173:CDOO_RS06490
uniprot id: A0A097IFS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

558173:CDOO RS10925
gene id: 558173:CDOO_RS10925
uniprot id: A0A097II11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS02740
gene id: 558173:CDOO_RS02740
uniprot id: A0A097IDT2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

558173:CDOO RS09950
gene id: 558173:CDOO_RS09950
uniprot id: A0A097IHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

558173:CDOO RS09985
gene id: 558173:CDOO_RS09985
uniprot id: A0A097IHI9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

558173:CDOO RS07395
gene id: 558173:CDOO_RS07395
uniprot id: A0A097IG64
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

558173:CDOO RS05115
gene id: 558173:CDOO_RS05115
uniprot id: A0A097IF22
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

558173:CDOO RS00585
gene id: 558173:CDOO_RS00585
uniprot id: A0A097ICY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS09505
gene id: 558173:CDOO_RS09505
uniprot id: A0A097IHA3
names: Similarity
messages: Belongs to the glutamine synthetase family.

558173:CDOO RS08500
gene id: 558173:CDOO_RS08500
uniprot id: A0A097IGP3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

558173:CDOO RS02875
gene id: 558173:CDOO_RS02875
uniprot id: A0A097IDX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

558173:CDOO RS03330
gene id: 558173:CDOO_RS03330
uniprot id: A0A097IE54
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

558173:CDOO RS08450
gene id: 558173:CDOO_RS08450
uniprot id: A0A097IGN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

558173:CDOO RS04655
gene id: 558173:CDOO_RS04655
uniprot id: A0A097IEU2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

558173:CDOO RS05740
gene id: 558173:CDOO_RS05740
uniprot id: A0A097IFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

558173:CDOO RS11940
gene id: 558173:CDOO_RS11940
uniprot id: A0A097III9
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07500
gene id: 558173:CDOO_RS07500
uniprot id: A0A097IGA2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

558173:CDOO RS07170
gene id: 558173:CDOO_RS07170
uniprot id: A0A097IG23
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

558173:CDOO RS02475
gene id: 558173:CDOO_RS02475
uniprot id: A0A097IDR3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

558173:CDOO RS04645
gene id: 558173:CDOO_RS04645
uniprot id: A0A097IEV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

558173:CDOO RS05065
gene id: 558173:CDOO_RS05065
uniprot id: A0A097IEZ2
names: Cofactor
messages: Binds 1 FMN per subunit.

558173:CDOO RS11660
gene id: 558173:CDOO_RS11660
uniprot id: A0A097IIC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

558173:CDOO RS10390
gene id: 558173:CDOO_RS10390
uniprot id: A0A097IHS2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS03915
gene id: 558173:CDOO_RS03915
uniprot id: A0A097IEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

558173:CDOO RS11055
gene id: 558173:CDOO_RS11055
uniprot id: A0A097II23
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS06730
gene id: 558173:CDOO_RS06730
uniprot id: A0A097IFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

558173:CDOO RS08590
gene id: 558173:CDOO_RS08590
uniprot id: A0A097IGV6
names: Similarity
messages: Belongs to the MQO family.

558173:CDOO RS06655
gene id: 558173:CDOO_RS06655
uniprot id: A0A097IFU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

558173:CDOO RS08320
gene id: 558173:CDOO_RS08320
uniprot id: A0A097IGR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS08460
gene id: 558173:CDOO_RS08460
uniprot id: A0A097IGR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

558173:CDOO RS10585
gene id: 558173:CDOO_RS10585
uniprot id: A0A097IHV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

558173:CDOO RS07060
gene id: 558173:CDOO_RS07060
uniprot id: A0A097IG11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

558173:CDOO RS01555
gene id: 558173:CDOO_RS01555
uniprot id: A0A097IDB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

558173:CDOO RS07565
gene id: 558173:CDOO_RS07565
uniprot id: A0A097IGD4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

558173:CDOO RS06915
gene id: 558173:CDOO_RS06915
uniprot id: A0A097IFY1
names: Subcellular Location Annotation
messages: Secreted

558173:CDOO RS12710
gene id: 558173:CDOO_RS12710
uniprot id: A0A097IIV9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

558173:CDOO RS02510
gene id: 558173:CDOO_RS02510
uniprot id: A0A097IDS6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

558173:CDOO RS09905
gene id: 558173:CDOO_RS09905
uniprot id: A0A097IHH6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

558173:CDOO RS09445
gene id: 558173:CDOO_RS09445
uniprot id: A0A097IH95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

558173:CDOO RS03650
gene id: 558173:CDOO_RS03650
uniprot id: A0A097IEB6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

558173:CDOO RS09190
gene id: 558173:CDOO_RS09190
uniprot id: A0A097IH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

558173:CDOO RS04415
gene id: 558173:CDOO_RS04415
uniprot id: A0A097IER3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS07250
gene id: 558173:CDOO_RS07250
uniprot id: A0A097IG39
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS05235
gene id: 558173:CDOO_RS05235
uniprot id: A0A097IF51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

558173:CDOO RS01670
gene id: 558173:CDOO_RS01670
uniprot id: A0A097IDC8
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

558173:CDOO RS12665
gene id: 558173:CDOO_RS12665
uniprot id: A0A097IIX8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS10210
gene id: 558173:CDOO_RS10210
uniprot id: A0A097IHL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

558173:CDOO RS05855
gene id: 558173:CDOO_RS05855
uniprot id: A0A097IFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

558173:CDOO RS06075
gene id: 558173:CDOO_RS06075
uniprot id: A0A097IFL1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06605
gene id: 558173:CDOO_RS06605
uniprot id: A0A097IFT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

558173:CDOO RS06635
gene id: 558173:CDOO_RS06635
uniprot id: A0A097IFU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

558173:CDOO RS04370
gene id: 558173:CDOO_RS04370
uniprot id: A0A097IEN9
names: Cofactor
messages: Can also use Mn(2+) ion.

558173:CDOO RS02675
gene id: 558173:CDOO_RS02675
uniprot id: A0A097IDU8
names: Similarity
messages: Belongs to the asp23 family.

558173:CDOO RS09350
gene id: 558173:CDOO_RS09350
uniprot id: A0A097IH37
names: Similarity
messages: Belongs to the peptidase C40 family.

558173:CDOO RS08560
gene id: 558173:CDOO_RS08560
uniprot id: A0A097IGV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS01370
gene id: 558173:CDOO_RS01370
uniprot id: A0A097ID96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

558173:CDOO RS11740
gene id: 558173:CDOO_RS11740
uniprot id: A0A097IIE1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

558173:CDOO RS01325
gene id: 558173:CDOO_RS01325
uniprot id: A0A097ID95
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

558173:CDOO RS11630
gene id: 558173:CDOO_RS11630
uniprot id: A0A097IIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS12415
gene id: 558173:CDOO_RS12415
uniprot id: A0A097IIT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

558173:CDOO RS03750
gene id: 558173:CDOO_RS03750
uniprot id: A0A097IEC4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

558173:CDOO RS09880
gene id: 558173:CDOO_RS09880
uniprot id: A0A097IHH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS03390
gene id: 558173:CDOO_RS03390
uniprot id: A0A097IE56
names: Similarity
messages: Belongs to the AccD/PCCB family.

558173:CDOO RS11580
gene id: 558173:CDOO_RS11580
uniprot id: A0A097IIB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

558173:CDOO RS05695
gene id: 558173:CDOO_RS05695
uniprot id: A0A097IFD0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

558173:CDOO RS04185
gene id: 558173:CDOO_RS04185
uniprot id: A0A097IEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

558173:CDOO RS00885
gene id: 558173:CDOO_RS00885
uniprot id: A0A097ID20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS08140
gene id: 558173:CDOO_RS08140
uniprot id: A0A097IGL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

558173:CDOO RS03730
gene id: 558173:CDOO_RS03730
uniprot id: A0A097IEC5
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

558173:CDOO RS07955
gene id: 558173:CDOO_RS07955
uniprot id: A0A097IGG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

558173:CDOO RS11495
gene id: 558173:CDOO_RS11495
uniprot id: A0A097IIB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

558173:CDOO RS02975
gene id: 558173:CDOO_RS02975
uniprot id: A0A097IDX5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

558173:CDOO RS01065
gene id: 558173:CDOO_RS01065
uniprot id: A0A097ID55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS10405
gene id: 558173:CDOO_RS10405
uniprot id: A0A097IHS5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

558173:CDOO RS08435
gene id: 558173:CDOO_RS08435
uniprot id: A0A097IGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

558173:CDOO RS06680
gene id: 558173:CDOO_RS06680
uniprot id: A0A097IFU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

558173:CDOO RS08785
gene id: 558173:CDOO_RS08785
uniprot id: A0A097IGZ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS03945
gene id: 558173:CDOO_RS03945
uniprot id: A0A097IEI5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

558173:CDOO RS03395
gene id: 558173:CDOO_RS03395
uniprot id: A0A097IE69
names: Similarity
messages: Belongs to the AccD/PCCB family.

558173:CDOO RS07520
gene id: 558173:CDOO_RS07520
uniprot id: A0A097IG86
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS09275
gene id: 558173:CDOO_RS09275
uniprot id: A0A097IH77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

558173:CDOO RS09065
gene id: 558173:CDOO_RS09065
uniprot id: A0A097IH19
names: Similarity
messages: Belongs to the HSP15 family.

558173:CDOO RS09920
gene id: 558173:CDOO_RS09920
uniprot id: A0A097IHJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

558173:CDOO RS00640
gene id: 558173:CDOO_RS00640
uniprot id: A0A097ICZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

558173:CDOO RS11015
gene id: 558173:CDOO_RS11015
uniprot id: A0A097II03
names: Similarity
messages: Belongs to the PhoU family.

558173:CDOO RS02710
gene id: 558173:CDOO_RS02710
uniprot id: A0A097IDU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

558173:CDOO RS04015
gene id: 558173:CDOO_RS04015
uniprot id: A0A097IEG6
names: Similarity
messages: Belongs to the FPG family.

558173:CDOO RS07530
gene id: 558173:CDOO_RS07530
uniprot id: A0A097IG99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

558173:CDOO RS09760
gene id: 558173:CDOO_RS09760
uniprot id: A0A097IHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

558173:CDOO RS04070
gene id: 558173:CDOO_RS04070
uniprot id: A0A097IJB1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07860
gene id: 558173:CDOO_RS07860
uniprot id: A0A097IGE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

558173:CDOO RS06720
gene id: 558173:CDOO_RS06720
uniprot id: A0A097IFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

558173:CDOO RS02955
gene id: 558173:CDOO_RS02955
uniprot id: A0A097IDZ9
names: Similarity
messages: Belongs to the WXG100 family.

558173:CDOO RS07505
gene id: 558173:CDOO_RS07505
uniprot id: A0A097IG94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

558173:CDOO RS08390
gene id: 558173:CDOO_RS08390
uniprot id: A0A097IGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

558173:CDOO RS10080
gene id: 558173:CDOO_RS10080
uniprot id: A0A097IHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

558173:CDOO RS11005
gene id: 558173:CDOO_RS11005
uniprot id: A0A097II14
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

558173:CDOO RS03230
gene id: 558173:CDOO_RS03230
uniprot id: A0A097IE53
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

558173:CDOO RS07485
gene id: 558173:CDOO_RS07485
uniprot id: A0A097IG92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

558173:CDOO RS02530
gene id: 558173:CDOO_RS02530
uniprot id: A0A097IDS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

558173:CDOO RS00010
gene id: 558173:CDOO_RS00010
uniprot id: A0A097ICM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

558173:CDOO RS10070
gene id: 558173:CDOO_RS10070
uniprot id: A0A097IHJ0
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

558173:CDOO RS06165
gene id: 558173:CDOO_RS06165
uniprot id: A0A097IFJ8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

558173:CDOO RS07510
gene id: 558173:CDOO_RS07510
uniprot id: A0A097IG98
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS07495
gene id: 558173:CDOO_RS07495
uniprot id: A0A097IG82
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

558173:CDOO RS06980
gene id: 558173:CDOO_RS06980
uniprot id: A0A097IFZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

558173:CDOO RS10895
gene id: 558173:CDOO_RS10895
uniprot id: A0A097IHY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS11030
gene id: 558173:CDOO_RS11030
uniprot id: A0A097II19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

558173:CDOO RS09770
gene id: 558173:CDOO_RS09770
uniprot id: A0A097IHF1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS02735
gene id: 558173:CDOO_RS02735
uniprot id: A0A097IDU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

558173:CDOO RS06585
gene id: 558173:CDOO_RS06585
uniprot id: A0A097IFS1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS11920
gene id: 558173:CDOO_RS11920
uniprot id: A0A097IIG1
names: Similarity
messages: Belongs to the asparaginase 1 family.

558173:CDOO RS09195
gene id: 558173:CDOO_RS09195
uniprot id: A0A097IH65
names: Similarity
messages: Belongs to the YggT family.

558173:CDOO RS09325
gene id: 558173:CDOO_RS09325
uniprot id: A0A097IH32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

558173:CDOO RS02230
gene id: 558173:CDOO_RS02230
uniprot id: A0A097IDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

558173:CDOO RS05075
gene id: 558173:CDOO_RS05075
uniprot id: A0A097IF18
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

558173:CDOO RS03920
gene id: 558173:CDOO_RS03920
uniprot id: A0A097IEI1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

558173:CDOO RS03075
gene id: 558173:CDOO_RS03075
uniprot id: A0A097IE06
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

558173:CDOO RS06715
gene id: 558173:CDOO_RS06715
uniprot id: A0A097IFV2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

558173:CDOO RS03170
gene id: 558173:CDOO_RS03170
uniprot id: A0A097IE11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

558173:CDOO RS09395
gene id: 558173:CDOO_RS09395
uniprot id: A0A097IH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

558173:CDOO RS08535
gene id: 558173:CDOO_RS08535
uniprot id: A0A097IGT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

558173:CDOO RS10590
gene id: 558173:CDOO_RS10590
uniprot id: A0A097IHV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

558173:CDOO RS00195
gene id: 558173:CDOO_RS00195
uniprot id: A0A097ICS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

558173:CDOO RS04675
gene id: 558173:CDOO_RS04675
uniprot id: A0A097IEU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS05430
gene id: 558173:CDOO_RS05430
uniprot id: A0A097IF76
names: Similarity
messages: Belongs to the LOG family.

558173:CDOO RS12700
gene id: 558173:CDOO_RS12700
uniprot id: A0A097IIW1
names: Similarity
messages: Belongs to the universal stress protein A family.

558173:CDOO RS04680
gene id: 558173:CDOO_RS04680
uniprot id: A0A097IEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

558173:CDOO RS03335
gene id: 558173:CDOO_RS03335
uniprot id: A0A097IE73
names: Similarity
messages: Belongs to the citrate synthase family.

558173:CDOO RS10095
gene id: 558173:CDOO_RS10095
uniprot id: A0A097IHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

558173:CDOO RS09380
gene id: 558173:CDOO_RS09380
uniprot id: A0A097IH86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

558173:CDOO RS07400
gene id: 558173:CDOO_RS07400
uniprot id: A0A097IG85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

558173:CDOO RS07780
gene id: 558173:CDOO_RS07780
uniprot id: A0A097IGG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

558173:CDOO RS05810
gene id: 558173:CDOO_RS05810
uniprot id: A0A097IFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

558173:CDOO RS07470
gene id: 558173:CDOO_RS07470
uniprot id: A0A097IG77
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

558173:CDOO RS08670
gene id: 558173:CDOO_RS08670
uniprot id: A0A097IGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

558173:CDOO RS01280
gene id: 558173:CDOO_RS01280
uniprot id: A0A097ID90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

558173:CDOO RS08305
gene id: 558173:CDOO_RS08305
uniprot id: A0A097IGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

558173:CDOO RS11335
gene id: 558173:CDOO_RS11335
uniprot id: A0A097II67
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

558173:CDOO RS00120
gene id: 558173:CDOO_RS00120
uniprot id: A0A097ICN9
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS08480
gene id: 558173:CDOO_RS08480
uniprot id: A0A097IGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

558173:CDOO RS07650
gene id: 558173:CDOO_RS07650
uniprot id: A0A097IGD8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

558173:CDOO RS07795
gene id: 558173:CDOO_RS07795
uniprot id: A0A097IGI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

558173:CDOO RS11850
gene id: 558173:CDOO_RS11850
uniprot id: A0A097IIF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS02290
gene id: 558173:CDOO_RS02290
uniprot id: A0A097IDM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS02425
gene id: 558173:CDOO_RS02425
uniprot id: A0A097IDQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS11040
gene id: 558173:CDOO_RS11040
uniprot id: A0A097II10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

558173:CDOO RS10545
gene id: 558173:CDOO_RS10545
uniprot id: A0A097IHU8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

558173:CDOO RS00575
gene id: 558173:CDOO_RS00575
uniprot id: A0A097ICX5
names: Similarity
messages: Belongs to the YciI family.

558173:CDOO RS12810
gene id: 558173:CDOO_RS12810
uniprot id: A0A097IJ00
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS03070
gene id: 558173:CDOO_RS03070
uniprot id: A0A097IDZ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

558173:CDOO RS00150
gene id: 558173:CDOO_RS00150
uniprot id: A0A097ICP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

558173:CDOO RS03205
gene id: 558173:CDOO_RS03205
uniprot id: A0A097IE47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

558173:CDOO RS00860
gene id: 558173:CDOO_RS00860
uniprot id: A0A097ID13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS04060
gene id: 558173:CDOO_RS04060
uniprot id: A0A097IEI2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

558173:CDOO RS05865
gene id: 558173:CDOO_RS05865
uniprot id: A0A097IFE2
names: Similarity
messages: Belongs to the UPF0045 family.

558173:CDOO RS08645
gene id: 558173:CDOO_RS08645
uniprot id: A0A097IGR7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS12645
gene id: 558173:CDOO_RS12645
uniprot id: A0A097IIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

558173:CDOO RS09120
gene id: 558173:CDOO_RS09120
uniprot id: A0A097IH30
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

558173:CDOO RS02540
gene id: 558173:CDOO_RS02540
uniprot id: A0A097IDR8
names: Similarity
messages: Belongs to the creatininase superfamily.

558173:CDOO RS06590
gene id: 558173:CDOO_RS06590
uniprot id: A0A097IFS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

558173:CDOO RS08715
gene id: 558173:CDOO_RS08715
uniprot id: A0A097IGU8
names: Similarity
messages: Belongs to the UPF0102 family.

558173:CDOO RS11155
gene id: 558173:CDOO_RS11155
uniprot id: A0A097II38
names: Similarity
messages: Belongs to the GARS family.

558173:CDOO RS00820
gene id: 558173:CDOO_RS00820
uniprot id: A0A097ID08
names: Similarity
messages: Belongs to the DprA/Smf family.

558173:CDOO RS02700
gene id: 558173:CDOO_RS02700
uniprot id: A0A097IDV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

558173:CDOO RS07965
gene id: 558173:CDOO_RS07965
uniprot id: A0A097IGI7
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

558173:CDOO RS04240
gene id: 558173:CDOO_RS04240
uniprot id: A0A097IEL2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10330
gene id: 558173:CDOO_RS10330
uniprot id: A0A097IHQ8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

558173:CDOO RS06180
gene id: 558173:CDOO_RS06180
uniprot id: A0A097IFL7
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS00285
gene id: 558173:CDOO_RS00285
uniprot id: A0A097ICS2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

558173:CDOO RS03780
gene id: 558173:CDOO_RS03780
uniprot id: A0A097IED1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

558173:CDOO RS03275
gene id: 558173:CDOO_RS03275
uniprot id: A0A097IE48
names: Similarity
messages: Belongs to the peptidase S11 family.

558173:CDOO RS09735
gene id: 558173:CDOO_RS09735
uniprot id: A0A097IHF0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

558173:CDOO RS07145
gene id: 558173:CDOO_RS07145
uniprot id: A0A097IG19
names: Similarity
messages: Belongs to the peptidase M18 family.

558173:CDOO RS05455
gene id: 558173:CDOO_RS05455
uniprot id: A0A097IF83
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

558173:CDOO RS09390
gene id: 558173:CDOO_RS09390
uniprot id: A0A097IH75
names: Similarity
messages: Belongs to the asparagine synthetase family.

558173:CDOO RS04765
gene id: 558173:CDOO_RS04765
uniprot id: A0A097IEU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

558173:CDOO RS07265
gene id: 558173:CDOO_RS07265
uniprot id: A0A097IG40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS11285
gene id: 558173:CDOO_RS11285
uniprot id: A0A097II58
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

558173:CDOO RS11480
gene id: 558173:CDOO_RS11480
uniprot id: A0A097II97
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

558173:CDOO RS08275
gene id: 558173:CDOO_RS08275
uniprot id: A0A097IGK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

558173:CDOO RS05605
gene id: 558173:CDOO_RS05605
uniprot id: A0A097IF96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

558173:CDOO RS01510
gene id: 558173:CDOO_RS01510
uniprot id: A0A097IDC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

558173:CDOO RS11105
gene id: 558173:CDOO_RS11105
uniprot id: A0A097II29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

558173:CDOO RS05495
gene id: 558173:CDOO_RS05495
uniprot id: A0A097IF84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

558173:CDOO RS04740
gene id: 558173:CDOO_RS04740
uniprot id: A0A097IET9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

558173:CDOO RS06105
gene id: 558173:CDOO_RS06105
uniprot id: A0A097IFL5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

558173:CDOO RS11935
gene id: 558173:CDOO_RS11935
uniprot id: A0A097IIH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

558173:CDOO RS03300
gene id: 558173:CDOO_RS03300
uniprot id: A0A097IE35
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

558173:CDOO RS04130
gene id: 558173:CDOO_RS04130
uniprot id: A0A097IEI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

558173:CDOO RS07195
gene id: 558173:CDOO_RS07195
uniprot id: A0A097IG30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

558173:CDOO RS04155
gene id: 558173:CDOO_RS04155
uniprot id: A0A097IEJ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

558173:CDOO RS02330
gene id: 558173:CDOO_RS02330
uniprot id: A0A097IDP7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

558173:CDOO RS10110
gene id: 558173:CDOO_RS10110
uniprot id: A0A097IHL8
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS08730
gene id: 558173:CDOO_RS08730
uniprot id: A0A097IGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

558173:CDOO RS05200
gene id: 558173:CDOO_RS05200
uniprot id: A0A097IF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS02385
gene id: 558173:CDOO_RS02385
uniprot id: A0A097IDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS03110
gene id: 558173:CDOO_RS03110
uniprot id: A0A097IE00
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

558173:CDOO RS11205
gene id: 558173:CDOO_RS11205
uniprot id: A0A097II57
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS08365
gene id: 558173:CDOO_RS08365
uniprot id: A0A097IGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS11020
gene id: 558173:CDOO_RS11020
uniprot id: A0A097II21
names: Similarity
messages: Belongs to the cytochrome P450 family.

558173:CDOO RS07445
gene id: 558173:CDOO_RS07445
uniprot id: A0A097IG72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

558173:CDOO RS02860
gene id: 558173:CDOO_RS02860
uniprot id: A0A097IDX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

558173:CDOO RS12325
gene id: 558173:CDOO_RS12325
uniprot id: A0A097IIP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS08285
gene id: 558173:CDOO_RS08285
uniprot id: A0A097IGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

558173:CDOO RS12805
gene id: 558173:CDOO_RS12805
uniprot id: A0A097IIX2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS11690
gene id: 558173:CDOO_RS11690
uniprot id: A0A097IID1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07750
gene id: 558173:CDOO_RS07750
uniprot id: A0A097IGC8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

558173:CDOO RS11625
gene id: 558173:CDOO_RS11625
uniprot id: A0A097IIC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS08485
gene id: 558173:CDOO_RS08485
uniprot id: A0A097IGS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

558173:CDOO RS10055
gene id: 558173:CDOO_RS10055
uniprot id: A0A097IHK9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

558173:CDOO RS04905
gene id: 558173:CDOO_RS04905
uniprot id: A0A097IEZ4
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS03520
gene id: 558173:CDOO_RS03520
uniprot id: A0A097IE83
names: Similarity
messages: Belongs to the thymidylate kinase family.

558173:CDOO RS07570
gene id: 558173:CDOO_RS07570
uniprot id: A0A097IG96
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

558173:CDOO RS07340
gene id: 558173:CDOO_RS07340
uniprot id: A0A097IG90
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

558173:CDOO RS12400
gene id: 558173:CDOO_RS12400
uniprot id: A0A097IIQ8
names: Similarity
messages: Belongs to the FGGY kinase family.

558173:CDOO RS02655
gene id: 558173:CDOO_RS02655
uniprot id: A0A097IDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

558173:CDOO RS06175
gene id: 558173:CDOO_RS06175
uniprot id: A0A097IFL0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS05175
gene id: 558173:CDOO_RS05175
uniprot id: A0A097IF37
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

558173:CDOO RS12860
gene id: 558173:CDOO_RS12860
uniprot id: A0A097IIY0
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

558173:CDOO RS12730
gene id: 558173:CDOO_RS12730
uniprot id: A0A097IIW7
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10645
gene id: 558173:CDOO_RS10645
uniprot id: A0A097IHU2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

558173:CDOO RS02025
gene id: 558173:CDOO_RS02025
uniprot id: A0A097IDI8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

558173:CDOO RS11475
gene id: 558173:CDOO_RS11475
uniprot id: A0A097II92
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

558173:CDOO RS12055
gene id: 558173:CDOO_RS12055
uniprot id: A0A097III7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS04200
gene id: 558173:CDOO_RS04200
uniprot id: A0A097IEN0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

558173:CDOO RS06095
gene id: 558173:CDOO_RS06095
uniprot id: A0A097IFJ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

558173:CDOO RS07555
gene id: 558173:CDOO_RS07555
uniprot id: A0A097IGA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

558173:CDOO RS10835
gene id: 558173:CDOO_RS10835
uniprot id: A0A097IHZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

558173:CDOO RS03025
gene id: 558173:CDOO_RS03025
uniprot id: A0A097IE10
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

558173:CDOO RS10500
gene id: 558173:CDOO_RS10500
uniprot id: A0A097IHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

558173:CDOO RS07730
gene id: 558173:CDOO_RS07730
uniprot id: A0A097IGE2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

558173:CDOO RS08745
gene id: 558173:CDOO_RS08745
uniprot id: A0A097IGZ6
names: Similarity
messages: Belongs to the peptidase M1 family.

558173:CDOO RS07125
gene id: 558173:CDOO_RS07125
uniprot id: A0A097IG21
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

558173:CDOO RS03595
gene id: 558173:CDOO_RS03595
uniprot id: A0A097IEA0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

558173:CDOO RS10295
gene id: 558173:CDOO_RS10295
uniprot id: A0A097IHM6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

558173:CDOO RS11965
gene id: 558173:CDOO_RS11965
uniprot id: A0A097IIJ4
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

558173:CDOO RS12970
gene id: 558173:CDOO_RS12970
uniprot id: A0A097IJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

558173:CDOO RS10020
gene id: 558173:CDOO_RS10020
uniprot id: A0A097IHK8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

558173:CDOO RS08220
gene id: 558173:CDOO_RS08220
uniprot id: A0A097IGM3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

558173:CDOO RS08310
gene id: 558173:CDOO_RS08310
uniprot id: A0A097IGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

558173:CDOO RS02995
gene id: 558173:CDOO_RS02995
uniprot id: A0A097IDY3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

558173:CDOO RS01045
gene id: 558173:CDOO_RS01045
uniprot id: A0A097ID43
names: Similarity
messages: Belongs to the peptidase M13 family.

558173:CDOO RS04595
gene id: 558173:CDOO_RS04595
uniprot id: A0A097IET2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

558173:CDOO RS04265
gene id: 558173:CDOO_RS04265
uniprot id: A0A097IEL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

558173:CDOO RS02790
gene id: 558173:CDOO_RS02790
uniprot id: A0A097IDV0
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10680
gene id: 558173:CDOO_RS10680
uniprot id: A0A097IHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

558173:CDOO RS12950
gene id: 558173:CDOO_RS12950
uniprot id: A0A097IJ11
names: Similarity
messages: Belongs to the ParB family.

558173:CDOO RS00185
gene id: 558173:CDOO_RS00185
uniprot id: A0A097ICT0
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

558173:CDOO RS10340
gene id: 558173:CDOO_RS10340
uniprot id: A0A097IHR2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

558173:CDOO RS06940
gene id: 558173:CDOO_RS06940
uniprot id: A0A097IG20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

558173:CDOO RS10385
gene id: 558173:CDOO_RS10385
uniprot id: A0A097IHR9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

558173:CDOO RS08930
gene id: 558173:CDOO_RS08930
uniprot id: A0A097IGZ9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

558173:CDOO RS07610
gene id: 558173:CDOO_RS07610
uniprot id: A0A097IGB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS12265
gene id: 558173:CDOO_RS12265
uniprot id: A0A097IIN1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS01230
gene id: 558173:CDOO_RS01230
uniprot id: A0A097ID76
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS02300
gene id: 558173:CDOO_RS02300
uniprot id: A0A097IDN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS01640
gene id: 558173:CDOO_RS01640
uniprot id: A0A097IDE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

558173:CDOO RS07050
gene id: 558173:CDOO_RS07050
uniprot id: A0A097IG38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS11315
gene id: 558173:CDOO_RS11315
uniprot id: A0A097II62
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

558173:CDOO RS06615
gene id: 558173:CDOO_RS06615
uniprot id: A0A097IFS6
names: Similarity
messages: Belongs to the universal stress protein A family.

558173:CDOO RS12865
gene id: 558173:CDOO_RS12865
uniprot id: A0A097IJ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

558173:CDOO RS05820
gene id: 558173:CDOO_RS05820
uniprot id: A0A097IFE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

558173:CDOO RS03685
gene id: 558173:CDOO_RS03685
uniprot id: A0A097IEB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

558173:CDOO RS12070
gene id: 558173:CDOO_RS12070
uniprot id: A0A097IIJ7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

558173:CDOO RS06675
gene id: 558173:CDOO_RS06675
uniprot id: A0A097IFW7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

558173:CDOO RS09620
gene id: 558173:CDOO_RS09620
uniprot id: A0A097IHE7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

558173:CDOO RS09840
gene id: 558173:CDOO_RS09840
uniprot id: A0A097IHH9
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

558173:CDOO RS10490
gene id: 558173:CDOO_RS10490
uniprot id: A0A097IHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

558173:CDOO RS05350
gene id: 558173:CDOO_RS05350
uniprot id: A0A097IF75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

558173:CDOO RS10225
gene id: 558173:CDOO_RS10225
uniprot id: A0A097IHP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

558173:CDOO RS10105
gene id: 558173:CDOO_RS10105
uniprot id: A0A097IHM3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

558173:CDOO RS04480
gene id: 558173:CDOO_RS04480
uniprot id: A0A097IEP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

558173:CDOO RS01205
gene id: 558173:CDOO_RS01205
uniprot id: A0A097ID79
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

558173:CDOO RS10320
gene id: 558173:CDOO_RS10320
uniprot id: A0A097IHN1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07600
gene id: 558173:CDOO_RS07600
uniprot id: A0A097IGC5
names: Similarity
messages: Belongs to the peptidase M24B family.

558173:CDOO RS02195
gene id: 558173:CDOO_RS02195
uniprot id: A0A097IDL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

558173:CDOO RS02720
gene id: 558173:CDOO_RS02720
uniprot id: A0A097IDV1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

558173:CDOO RS03490
gene id: 558173:CDOO_RS03490
uniprot id: A0A097IE77
names: Similarity
messages: Belongs to the phosphohexose mutase family.

558173:CDOO RS00015
gene id: 558173:CDOO_RS00015
uniprot id: A0A097ICM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

558173:CDOO RS00425
gene id: 558173:CDOO_RS00425
uniprot id: A0A097ICU4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

558173:CDOO RS11350
gene id: 558173:CDOO_RS11350
uniprot id: A0A097II68
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

558173:CDOO RS10160
gene id: 558173:CDOO_RS10160
uniprot id: A0A097IHN2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

558173:CDOO RS10345
gene id: 558173:CDOO_RS10345
uniprot id: A0A097IHN7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

558173:CDOO RS01475
gene id: 558173:CDOO_RS01475
uniprot id: A0A097IDB8
names: Similarity
messages: Belongs to the catalase family.

558173:CDOO RS08360
gene id: 558173:CDOO_RS08360
uniprot id: A0A097IGQ1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

558173:CDOO RS05130
gene id: 558173:CDOO_RS05130
uniprot id: A0A097IF29
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

558173:CDOO RS01430
gene id: 558173:CDOO_RS01430
uniprot id: A0A097ID93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

558173:CDOO RS02370
gene id: 558173:CDOO_RS02370
uniprot id: A0A097IDM6
names: Similarity
messages: Belongs to the YjdM family.

558173:CDOO RS08265
gene id: 558173:CDOO_RS08265
uniprot id: A0A097IGQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

558173:CDOO RS06210
gene id: 558173:CDOO_RS06210
uniprot id: A0A097IFN5
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

558173:CDOO RS02420
gene id: 558173:CDOO_RS02420
uniprot id: A0A097IDP9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

558173:CDOO RS00400
gene id: 558173:CDOO_RS00400
uniprot id: A0A097ICT8
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

558173:CDOO RS02270
gene id: 558173:CDOO_RS02270
uniprot id: A0A097IDN1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

558173:CDOO RS05905
gene id: 558173:CDOO_RS05905
uniprot id: A0A097IFG7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

558173:CDOO RS05835
gene id: 558173:CDOO_RS05835
uniprot id: A0A097IFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

558173:CDOO RS02430
gene id: 558173:CDOO_RS02430
uniprot id: A0A097IDN9
names: Similarity
messages: Belongs to the peptidase S51 family.

558173:CDOO RS11330
gene id: 558173:CDOO_RS11330
uniprot id: A0A097II85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS05935
gene id: 558173:CDOO_RS05935
uniprot id: A0A097IFH1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

558173:CDOO RS01175
gene id: 558173:CDOO_RS01175
uniprot id: A0A097ID75
names: Similarity
messages: Belongs to the OsmC/Ohr family.

558173:CDOO RS04355
gene id: 558173:CDOO_RS04355
uniprot id: A0A097IEN8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

558173:CDOO RS00635
gene id: 558173:CDOO_RS00635
uniprot id: A0A097ICY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

558173:CDOO RS09835
gene id: 558173:CDOO_RS09835
uniprot id: A0A097IHE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

558173:CDOO RS10915
gene id: 558173:CDOO_RS10915
uniprot id: A0A097II18
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS08895
gene id: 558173:CDOO_RS08895
uniprot id: A0A097IH11
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

558173:CDOO RS09610
gene id: 558173:CDOO_RS09610
uniprot id: A0A097IHC2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

558173:CDOO RS10945
gene id: 558173:CDOO_RS10945
uniprot id: A0A097II08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS10420
gene id: 558173:CDOO_RS10420
uniprot id: A0A097IHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

558173:CDOO RS12815
gene id: 558173:CDOO_RS12815
uniprot id: A0A097IIY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS10710
gene id: 558173:CDOO_RS10710
uniprot id: A0A097IHX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

558173:CDOO RS10825
gene id: 558173:CDOO_RS10825
uniprot id: A0A097II02
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

558173:CDOO RS04635
gene id: 558173:CDOO_RS04635
uniprot id: A0A097IES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS07305
gene id: 558173:CDOO_RS07305
uniprot id: A0A097IG50
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

558173:CDOO RS06820
gene id: 558173:CDOO_RS06820
uniprot id: A0A097IFW4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

558173:CDOO RS12190
gene id: 558173:CDOO_RS12190
uniprot id: A0A097IIL6
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

558173:CDOO RS01300
gene id: 558173:CDOO_RS01300
uniprot id: A0A097ID78
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS11760
gene id: 558173:CDOO_RS11760
uniprot id: A0A097IIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS12820
gene id: 558173:CDOO_RS12820
uniprot id: A0A097IIY4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

558173:CDOO RS11820
gene id: 558173:CDOO_RS11820
uniprot id: A0A097IIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS06120
gene id: 558173:CDOO_RS06120
uniprot id: A0A097IFK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

558173:CDOO RS12530
gene id: 558173:CDOO_RS12530
uniprot id: A0A097IIT1
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS12495
gene id: 558173:CDOO_RS12495
uniprot id: A0A097IIU9
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10840
gene id: 558173:CDOO_RS10840
uniprot id: A0A097IHZ4
names: Similarity
messages: Belongs to the fructosamine kinase family.

558173:CDOO RS08835
gene id: 558173:CDOO_RS08835
uniprot id: A0A097IGU9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

558173:CDOO RS12590
gene id: 558173:CDOO_RS12590
uniprot id: A0A097IIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

558173:CDOO RS12270
gene id: 558173:CDOO_RS12270
uniprot id: A0A097IIN0
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS07645
gene id: 558173:CDOO_RS07645
uniprot id: A0A097IGA7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

558173:CDOO RS02070
gene id: 558173:CDOO_RS02070
uniprot id: A0A097IDG9
names: Similarity
messages: Belongs to the peptidase M1 family.

558173:CDOO RS03225
gene id: 558173:CDOO_RS03225
uniprot id: A0A097IE38
names: Similarity
messages: Belongs to the band 7/mec-2 family.

558173:CDOO RS07770
gene id: 558173:CDOO_RS07770
uniprot id: A0A097IGH6
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10960
gene id: 558173:CDOO_RS10960
uniprot id: A0A097IHZ8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

558173:CDOO RS12660
gene id: 558173:CDOO_RS12660
uniprot id: A0A097IIU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

558173:CDOO RS08295
gene id: 558173:CDOO_RS08295
uniprot id: A0A097IGR1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

558173:CDOO RS03050
gene id: 558173:CDOO_RS03050
uniprot id: A0A097IE01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

558173:CDOO RS09465
gene id: 558173:CDOO_RS09465
uniprot id: A0A097IHA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

558173:CDOO RS09205
gene id: 558173:CDOO_RS09205
uniprot id: A0A097IH45
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

558173:CDOO RS01295
gene id: 558173:CDOO_RS01295
uniprot id: A0A097ID87
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS10040
gene id: 558173:CDOO_RS10040
uniprot id: A0A097IHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

558173:CDOO RS07595
gene id: 558173:CDOO_RS07595
uniprot id: A0A097IGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

558173:CDOO RS07800
gene id: 558173:CDOO_RS07800
uniprot id: A0A097IGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

558173:CDOO RS02820
gene id: 558173:CDOO_RS02820
uniprot id: A0A097IDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

558173:CDOO RS06875
gene id: 558173:CDOO_RS06875
uniprot id: A0A097IFX9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

558173:CDOO RS08700
gene id: 558173:CDOO_RS08700
uniprot id: A0A097IGS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

558173:CDOO RS03635
gene id: 558173:CDOO_RS03635
uniprot id: A0A097IEB2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

558173:CDOO RS01500
gene id: 558173:CDOO_RS01500
uniprot id: A0A097IDC2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS05285
gene id: 558173:CDOO_RS05285
uniprot id: A0A097IF35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

558173:CDOO RS06685
gene id: 558173:CDOO_RS06685
uniprot id: A0A097IFU8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

558173:CDOO RS01660
gene id: 558173:CDOO_RS01660
uniprot id: A0A097IDE5
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS02500
gene id: 558173:CDOO_RS02500
uniprot id: A0A097IDP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

558173:CDOO RS12250
gene id: 558173:CDOO_RS12250
uniprot id: A0A097IIN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

558173:CDOO RS10605
gene id: 558173:CDOO_RS10605
uniprot id: A0A097IHW0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

558173:CDOO RS03535
gene id: 558173:CDOO_RS03535
uniprot id: A0A097IE91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

558173:CDOO RS01410
gene id: 558173:CDOO_RS01410
uniprot id: A0A097IDA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

558173:CDOO RS04555
gene id: 558173:CDOO_RS04555
uniprot id: A0A097IES5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

558173:CDOO RS12030
gene id: 558173:CDOO_RS12030
uniprot id: A0A097III2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

558173:CDOO RS09630
gene id: 558173:CDOO_RS09630
uniprot id: A0A097IHC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

558173:CDOO RS10440
gene id: 558173:CDOO_RS10440
uniprot id: A0A097IHS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

558173:CDOO RS10410
gene id: 558173:CDOO_RS10410
uniprot id: A0A097IHS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

558173:CDOO RS01595
gene id: 558173:CDOO_RS01595
uniprot id: A0A097IDC7
names: Similarity
messages: Belongs to the GSP E family.

558173:CDOO RS05210
gene id: 558173:CDOO_RS05210
uniprot id: A0A097IF45
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

558173:CDOO RS06990
gene id: 558173:CDOO_RS06990
uniprot id: A0A097IG29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

558173:CDOO RS11140
gene id: 558173:CDOO_RS11140
uniprot id: A0A097II55
names: Similarity
messages: Belongs to the SAICAR synthetase family.

558173:CDOO RS07720
gene id: 558173:CDOO_RS07720
uniprot id: A0A097IGC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

558173:CDOO RS10035
gene id: 558173:CDOO_RS10035
uniprot id: A0A097IHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

558173:CDOO RS09440
gene id: 558173:CDOO_RS09440
uniprot id: A0A097IH97
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

558173:CDOO RS12010
gene id: 558173:CDOO_RS12010
uniprot id: A0A097IIJ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

558173:CDOO RS07070
gene id: 558173:CDOO_RS07070
uniprot id: A0A097IG14
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

558173:CDOO RS02905
gene id: 558173:CDOO_RS02905
uniprot id: A0A097IDW2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

558173:CDOO RS07450
gene id: 558173:CDOO_RS07450
uniprot id: A0A097IG93
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

558173:CDOO RS03765
gene id: 558173:CDOO_RS03765
uniprot id: A0A097IED0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

558173:CDOO RS03090
gene id: 558173:CDOO_RS03090
uniprot id: A0A097IE13
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

558173:CDOO RS02325
gene id: 558173:CDOO_RS02325
uniprot id: A0A097IDP2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS03550
gene id: 558173:CDOO_RS03550
uniprot id: A0A097IE97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

558173:CDOO RS07540
gene id: 558173:CDOO_RS07540
uniprot id: A0A097IGC9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

558173:CDOO RS11615
gene id: 558173:CDOO_RS11615
uniprot id: A0A097IID3
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS06135
gene id: 558173:CDOO_RS06135
uniprot id: A0A097IFJ2
names: Subcellular Location Annotation
messages: Membrane

558173:CDOO RS12680
gene id: 558173:CDOO_RS12680
uniprot id: A0A097IIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

558173:CDOO RS07785
gene id: 558173:CDOO_RS07785
uniprot id: A0A097IGF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.