557599:MKAN RS11610
gene id: 557599:MKAN_RS11610
uniprot id: U5WP39
names: Subcellular Location Annotation
messages: Secreted

557599:MKAN RS00635
gene id: 557599:MKAN_RS00635
uniprot id: U5WIF7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

557599:MKAN RS23680
gene id: 557599:MKAN_RS23680
uniprot id: U5WZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

557599:MKAN RS19205
gene id: 557599:MKAN_RS19205
uniprot id: U5WT51
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

557599:MKAN RS03075
gene id: 557599:MKAN_RS03075
uniprot id: U5WNB1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS26890
gene id: 557599:MKAN_RS26890
uniprot id: U5WWY4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

557599:MKAN RS02890
gene id: 557599:MKAN_RS02890
uniprot id: U5WMV3
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

557599:MKAN RS17410
gene id: 557599:MKAN_RS17410
uniprot id: U5WVB3
names: Cofactor
messages: Can also use Mn(2+) ion.

557599:MKAN RS25710
gene id: 557599:MKAN_RS25710
uniprot id: U5WWB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

557599:MKAN RS15525
gene id: 557599:MKAN_RS15525
uniprot id: U5WR32
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS20220
gene id: 557599:MKAN_RS20220
uniprot id: U5WWX6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

557599:MKAN RS26550
gene id: 557599:MKAN_RS26550
uniprot id: U5WXM8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

557599:MKAN RS27725
gene id: 557599:MKAN_RS27725
uniprot id: U5X0N7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS15430
gene id: 557599:MKAN_RS15430
uniprot id: U5WR65
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

557599:MKAN RS14240
gene id: 557599:MKAN_RS14240
uniprot id: U5WQA9
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS14075
gene id: 557599:MKAN_RS14075
uniprot id: U5WTZ2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS11040
gene id: 557599:MKAN_RS11040
uniprot id: U5WPF7
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

557599:MKAN RS11000
gene id: 557599:MKAN_RS11000
uniprot id: U5WNL1
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS24180
gene id: 557599:MKAN_RS24180
uniprot id: U5WVU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS17705
gene id: 557599:MKAN_RS17705
uniprot id: U5WVL4
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS25500
gene id: 557599:MKAN_RS25500
uniprot id: U5WZK1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

557599:MKAN RS12740
gene id: 557599:MKAN_RS12740
uniprot id: U5WQD3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

557599:MKAN RS14160
gene id: 557599:MKAN_RS14160
uniprot id: U5WR28
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

557599:MKAN RS14530
gene id: 557599:MKAN_RS14530
uniprot id: U5WU69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

557599:MKAN RS26925
gene id: 557599:MKAN_RS26925
uniprot id: U5WWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

557599:MKAN RS26410
gene id: 557599:MKAN_RS26410
uniprot id: U5X027
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS20795
gene id: 557599:MKAN_RS20795
uniprot id: U5WX84
names: Similarity
messages: Belongs to the peptidase S16 family.

557599:MKAN RS08215
gene id: 557599:MKAN_RS08215
uniprot id: U5WMZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

557599:MKAN RS20000
gene id: 557599:MKAN_RS20000
uniprot id: U5WTD0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS20370
gene id: 557599:MKAN_RS20370
uniprot id: U5WX25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

557599:MKAN RS08425
gene id: 557599:MKAN_RS08425
uniprot id: U5WMH3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

557599:MKAN RS06480
gene id: 557599:MKAN_RS06480
uniprot id: U5WQ21
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS11465
gene id: 557599:MKAN_RS11465
uniprot id: U5WNT7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS02860
gene id: 557599:MKAN_RS02860
uniprot id: U5WJN0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

557599:MKAN RS20415
gene id: 557599:MKAN_RS20415
uniprot id: U5WTQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

557599:MKAN RS27705
gene id: 557599:MKAN_RS27705
uniprot id: U5X136
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS16990
gene id: 557599:MKAN_RS16990
uniprot id: U5WZD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

557599:MKAN RS15885
gene id: 557599:MKAN_RS15885
uniprot id: U5WUJ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS14800
gene id: 557599:MKAN_RS14800
uniprot id: U5WQR9
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS02315
gene id: 557599:MKAN_RS02315
uniprot id: U5WJX1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

557599:MKAN RS20145
gene id: 557599:MKAN_RS20145
uniprot id: U5WWT6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

557599:MKAN RS04610
gene id: 557599:MKAN_RS04610
uniprot id: U5WP57
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS19285
gene id: 557599:MKAN_RS19285
uniprot id: U5WWD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

557599:MKAN RS21380
gene id: 557599:MKAN_RS21380
uniprot id: U5WU38
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS16805
gene id: 557599:MKAN_RS16805
uniprot id: U5WRN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

557599:MKAN RS11845
gene id: 557599:MKAN_RS11845
uniprot id: U5WP17
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

557599:MKAN RS09395
gene id: 557599:MKAN_RS09395
uniprot id: U5WNQ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS06260
gene id: 557599:MKAN_RS06260
uniprot id: U5WPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS05920
gene id: 557599:MKAN_RS05920
uniprot id: U5WL74
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

557599:MKAN RS11160
gene id: 557599:MKAN_RS11160
uniprot id: U5WSG5
names: Similarity
messages: Belongs to the TPP enzyme family.

557599:MKAN RS09275
gene id: 557599:MKAN_RS09275
uniprot id: U5WR37
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS19765
gene id: 557599:MKAN_RS19765
uniprot id: U5WWM5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

557599:MKAN RS22505
gene id: 557599:MKAN_RS22505
uniprot id: U5WUX8
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS16145
gene id: 557599:MKAN_RS16145
uniprot id: U5WRD5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS09140
gene id: 557599:MKAN_RS09140
uniprot id: U5WMV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

557599:MKAN RS04465
gene id: 557599:MKAN_RS04465
uniprot id: U5WKE1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

557599:MKAN RS01740
gene id: 557599:MKAN_RS01740
uniprot id: U5WJ26
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS05975
gene id: 557599:MKAN_RS05975
uniprot id: U5WPD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

557599:MKAN RS02625
gene id: 557599:MKAN_RS02625
uniprot id: U5WJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

557599:MKAN RS07570
gene id: 557599:MKAN_RS07570
uniprot id: U5WQ92
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

557599:MKAN RS08925
gene id: 557599:MKAN_RS08925
uniprot id: U5WMS1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS03235
gene id: 557599:MKAN_RS03235
uniprot id: U5WN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm

557599:MKAN RS08230
gene id: 557599:MKAN_RS08230
uniprot id: U5WQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

557599:MKAN RS26940
gene id: 557599:MKAN_RS26940
uniprot id: U5X0R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

557599:MKAN RS01120
gene id: 557599:MKAN_RS01120
uniprot id: U5WME1
names: Subcellular Location Annotation
messages: Cytoplasm

557599:MKAN RS01785
gene id: 557599:MKAN_RS01785
uniprot id: U5WMQ8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

557599:MKAN RS18310
gene id: 557599:MKAN_RS18310
uniprot id: U5WW98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

557599:MKAN RS28340
gene id: 557599:MKAN_RS28340
uniprot id: U5X0G4
names: Similarity
messages: Belongs to the YoeB family.

557599:MKAN RS14475
gene id: 557599:MKAN_RS14475
uniprot id: U5WQF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

557599:MKAN RS18000
gene id: 557599:MKAN_RS18000
uniprot id: U5WW48
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

557599:MKAN RS23370
gene id: 557599:MKAN_RS23370
uniprot id: U5WYK3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

557599:MKAN RS03185
gene id: 557599:MKAN_RS03185
uniprot id: U5WN01
names: Similarity
messages: Belongs to the peptidase S33 family.

557599:MKAN RS06695
gene id: 557599:MKAN_RS06695
uniprot id: U5WLJ9
names: Function
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

557599:MKAN RS14905
gene id: 557599:MKAN_RS14905
uniprot id: U5WUF8
names: Similarity
messages: Belongs to the PrpF family.

557599:MKAN RS23635
gene id: 557599:MKAN_RS23635
uniprot id: U5WVB4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS00205
gene id: 557599:MKAN_RS00205
uniprot id: U5WIB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

557599:MKAN RS13310
gene id: 557599:MKAN_RS13310
uniprot id: U5WT63
names: Similarity
messages: Belongs to the serpin family.

557599:MKAN RS24650
gene id: 557599:MKAN_RS24650
uniprot id: U5WZ51
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

557599:MKAN RS22175
gene id: 557599:MKAN_RS22175
uniprot id: U5WVB0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS05590
gene id: 557599:MKAN_RS05590
uniprot id: U5WLK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS12690
gene id: 557599:MKAN_RS12690
uniprot id: U5WQC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

557599:MKAN RS23800
gene id: 557599:MKAN_RS23800
uniprot id: U5WYR4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS16010
gene id: 557599:MKAN_RS16010
uniprot id: U5WS47
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

557599:MKAN RS24125
gene id: 557599:MKAN_RS24125
uniprot id: U5WVJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

557599:MKAN RS14925
gene id: 557599:MKAN_RS14925
uniprot id: U5WU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

557599:MKAN RS19165
gene id: 557599:MKAN_RS19165
uniprot id: U5WWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

557599:MKAN RS20250
gene id: 557599:MKAN_RS20250
uniprot id: U5WXC0
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Monovalent cation. The ion could be potassium.

557599:MKAN RS07090
gene id: 557599:MKAN_RS07090
uniprot id: U5WMG3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

557599:MKAN RS07025
gene id: 557599:MKAN_RS07025
uniprot id: U5WME8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

557599:MKAN RS21630
gene id: 557599:MKAN_RS21630
uniprot id: U5WXM4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

557599:MKAN RS24955
gene id: 557599:MKAN_RS24955
uniprot id: U5WZR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

557599:MKAN RS03080
gene id: 557599:MKAN_RS03080
uniprot id: U5WK98
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS08985
gene id: 557599:MKAN_RS08985
uniprot id: U5WRD6
names: Similarity
messages: Belongs to the citrate synthase family.

557599:MKAN RS02970
gene id: 557599:MKAN_RS02970
uniprot id: U5WN90
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS23135
gene id: 557599:MKAN_RS23135
uniprot id: U5WVB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

557599:MKAN RS07670
gene id: 557599:MKAN_RS07670
uniprot id: U5WLZ6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

557599:MKAN RS27080
gene id: 557599:MKAN_RS27080
uniprot id: U5WXB6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

557599:MKAN RS19860
gene id: 557599:MKAN_RS19860
uniprot id: U5WTA1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

557599:MKAN RS03425
gene id: 557599:MKAN_RS03425
uniprot id: U5WNH6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

557599:MKAN RS00490
gene id: 557599:MKAN_RS00490
uniprot id: U5WLM1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

557599:MKAN RS11615
gene id: 557599:MKAN_RS11615
uniprot id: U5WS89
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS26445
gene id: 557599:MKAN_RS26445
uniprot id: U5WXK6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS18515
gene id: 557599:MKAN_RS18515
uniprot id: U5WTF7
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS03005
gene id: 557599:MKAN_RS03005
uniprot id: U5WJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

557599:MKAN RS00400
gene id: 557599:MKAN_RS00400
uniprot id: U5WIF0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS14135
gene id: 557599:MKAN_RS14135
uniprot id: U5WQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

557599:MKAN RS06730
gene id: 557599:MKAN_RS06730
uniprot id: U5WPV8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

557599:MKAN RS01005
gene id: 557599:MKAN_RS01005
uniprot id: U5WM96
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

557599:MKAN RS16965
gene id: 557599:MKAN_RS16965
uniprot id: U5WVG8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

557599:MKAN RS05150
gene id: 557599:MKAN_RS05150
uniprot id: U5WP06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

557599:MKAN RS07975
gene id: 557599:MKAN_RS07975
uniprot id: U5WP40
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS19720
gene id: 557599:MKAN_RS19720
uniprot id: U5WWY7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS25715
gene id: 557599:MKAN_RS25715
uniprot id: U5WWL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

557599:MKAN RS16455
gene id: 557599:MKAN_RS16455
uniprot id: U5WUV4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

557599:MKAN RS00325
gene id: 557599:MKAN_RS00325
uniprot id: U5WLJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

557599:MKAN RS05540
gene id: 557599:MKAN_RS05540
uniprot id: U5WLK1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS11330
gene id: 557599:MKAN_RS11330
uniprot id: U5WNR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS26645
gene id: 557599:MKAN_RS26645
uniprot id: U5WWU8
names: Similarity
messages: Belongs to the TrpC family.

557599:MKAN RS06135
gene id: 557599:MKAN_RS06135
uniprot id: U5WLB6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

557599:MKAN RS22865
gene id: 557599:MKAN_RS22865
uniprot id: U5WV34
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

557599:MKAN RS24960
gene id: 557599:MKAN_RS24960
uniprot id: U5WWS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

557599:MKAN RS14695
gene id: 557599:MKAN_RS14695
uniprot id: U5WQQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

557599:MKAN RS14145
gene id: 557599:MKAN_RS14145
uniprot id: U5WTL1
names: Similarity
messages: Belongs to the UPF0232 family.

557599:MKAN RS06440
gene id: 557599:MKAN_RS06440
uniprot id: U5WLH0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS12785
gene id: 557599:MKAN_RS12785
uniprot id: U5WTE6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

557599:MKAN RS24310
gene id: 557599:MKAN_RS24310
uniprot id: U5WZ03
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS23405
gene id: 557599:MKAN_RS23405
uniprot id: U5WW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

557599:MKAN RS26385
gene id: 557599:MKAN_RS26385
uniprot id: U5X024
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

557599:MKAN RS23460
gene id: 557599:MKAN_RS23460
uniprot id: U5WW10
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS07815
gene id: 557599:MKAN_RS07815
uniprot id: U5WMU0
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS18655
gene id: 557599:MKAN_RS18655
uniprot id: U5WSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

557599:MKAN RS14585
gene id: 557599:MKAN_RS14585
uniprot id: U5WU80
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS06905
gene id: 557599:MKAN_RS06905
uniprot id: U5WLM8
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS25290
gene id: 557599:MKAN_RS25290
uniprot id: U5WWY3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

557599:MKAN RS26530
gene id: 557599:MKAN_RS26530
uniprot id: U5WWT1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

557599:MKAN RS26355
gene id: 557599:MKAN_RS26355
uniprot id: U5WX01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

557599:MKAN RS11545
gene id: 557599:MKAN_RS11545
uniprot id: U5WNV3
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

557599:MKAN RS23140
gene id: 557599:MKAN_RS23140
uniprot id: U5WYG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

557599:MKAN RS09125
gene id: 557599:MKAN_RS09125
uniprot id: U5WRG5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

557599:MKAN RS10225
gene id: 557599:MKAN_RS10225
uniprot id: U5WRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

557599:MKAN RS13665
gene id: 557599:MKAN_RS13665
uniprot id: U5WQT8
names: Subunit
messages: Homodimer.

557599:MKAN RS15455
gene id: 557599:MKAN_RS15455
uniprot id: U5WR69
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS02715
gene id: 557599:MKAN_RS02715
uniprot id: U5WK38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

557599:MKAN RS17690
gene id: 557599:MKAN_RS17690
uniprot id: U5WT20
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

557599:MKAN RS22975
gene id: 557599:MKAN_RS22975
uniprot id: U5WY99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

557599:MKAN RS10440
gene id: 557599:MKAN_RS10440
uniprot id: U5WP73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

557599:MKAN RS11805
gene id: 557599:MKAN_RS11805
uniprot id: U5WSC2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS07165
gene id: 557599:MKAN_RS07165
uniprot id: U5WLS3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS16100
gene id: 557599:MKAN_RS16100
uniprot id: U5WUP5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS12155
gene id: 557599:MKAN_RS12155
uniprot id: U5WSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS22435
gene id: 557599:MKAN_RS22435
uniprot id: U5WY01
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

557599:MKAN RS12125
gene id: 557599:MKAN_RS12125
uniprot id: U5WPD7
names: Similarity
messages: Belongs to the GSP E family.

557599:MKAN RS19680
gene id: 557599:MKAN_RS19680
uniprot id: U5WT69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

557599:MKAN RS20105
gene id: 557599:MKAN_RS20105
uniprot id: U5WU98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

557599:MKAN RS12715
gene id: 557599:MKAN_RS12715
uniprot id: U5WQC9
names: Similarity
messages: Belongs to the catalase family.

557599:MKAN RS02180
gene id: 557599:MKAN_RS02180
uniprot id: U5WMI0
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

557599:MKAN RS18850
gene id: 557599:MKAN_RS18850
uniprot id: U5WWI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

557599:MKAN RS23480
gene id: 557599:MKAN_RS23480
uniprot id: U5WZ22
names: Similarity
messages: Belongs to the HupF/HypC family.

557599:MKAN RS15075
gene id: 557599:MKAN_RS15075
uniprot id: U5WR06
names: Similarity
messages: Belongs to the TPP enzyme family.

557599:MKAN RS00155
gene id: 557599:MKAN_RS00155
uniprot id: U5WIA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

557599:MKAN RS23625
gene id: 557599:MKAN_RS23625
uniprot id: U5WZ49
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

557599:MKAN RS06085
gene id: 557599:MKAN_RS06085
uniprot id: U5WLA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

557599:MKAN RS26805
gene id: 557599:MKAN_RS26805
uniprot id: U5WWX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS16830
gene id: 557599:MKAN_RS16830
uniprot id: U5WRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS00915
gene id: 557599:MKAN_RS00915
uniprot id: U5WLV6
names: Similarity
messages: Belongs to the UPF0098 family.

557599:MKAN RS22645
gene id: 557599:MKAN_RS22645
uniprot id: U5WY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

557599:MKAN RS04990
gene id: 557599:MKAN_RS04990
uniprot id: U5WKR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

557599:MKAN RS05970
gene id: 557599:MKAN_RS05970
uniprot id: U5WL83
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

557599:MKAN RS18490
gene id: 557599:MKAN_RS18490
uniprot id: U5WTF2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

557599:MKAN RS26790
gene id: 557599:MKAN_RS26790
uniprot id: U5X081
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS05110
gene id: 557599:MKAN_RS05110
uniprot id: U5WLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

557599:MKAN RS06235
gene id: 557599:MKAN_RS06235
uniprot id: U5WPX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

557599:MKAN RS14065
gene id: 557599:MKAN_RS14065
uniprot id: U5WQD9
names: Similarity
messages: Belongs to the thioredoxin family.

557599:MKAN RS17400
gene id: 557599:MKAN_RS17400
uniprot id: U5WRZ9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

557599:MKAN RS22135
gene id: 557599:MKAN_RS22135
uniprot id: U5WUQ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS23760
gene id: 557599:MKAN_RS23760
uniprot id: U5WW66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

557599:MKAN RS18520
gene id: 557599:MKAN_RS18520
uniprot id: U5WSL3
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS25435
gene id: 557599:MKAN_RS25435
uniprot id: U5WWF9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS18065
gene id: 557599:MKAN_RS18065
uniprot id: U5WVS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS16955
gene id: 557599:MKAN_RS16955
uniprot id: U5WRX2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

557599:MKAN RS14300
gene id: 557599:MKAN_RS14300
uniprot id: U5WQC1
names: Similarity
messages: Belongs to the pirin family.

557599:MKAN RS22590
gene id: 557599:MKAN_RS22590
uniprot id: U5WUZ1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

557599:MKAN RS22555
gene id: 557599:MKAN_RS22555
uniprot id: U5WVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial histone-like protein family.
messages: cell wall

557599:MKAN RS16060
gene id: 557599:MKAN_RS16060
uniprot id: U5WS55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

557599:MKAN RS06075
gene id: 557599:MKAN_RS06075
uniprot id: U5WLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: In the C-terminal section; belongs to the ATPase delta chain family.
messages: In the N-terminal section; belongs to the ATPase B chain family.
messages: Membrane
messages: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0).
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

557599:MKAN RS11960
gene id: 557599:MKAN_RS11960
uniprot id: U5WSF2
names: Similarity
messages: Belongs to the peptidase S13 family.

557599:MKAN RS22650
gene id: 557599:MKAN_RS22650
uniprot id: U5WYF2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

557599:MKAN RS24150
gene id: 557599:MKAN_RS24150
uniprot id: U5WVJ8
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

557599:MKAN RS20375
gene id: 557599:MKAN_RS20375
uniprot id: U5WXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

557599:MKAN RS06095
gene id: 557599:MKAN_RS06095
uniprot id: U5WPU3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS10450
gene id: 557599:MKAN_RS10450
uniprot id: U5WNJ6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS06980
gene id: 557599:MKAN_RS06980
uniprot id: U5WLP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

557599:MKAN RS15355
gene id: 557599:MKAN_RS15355
uniprot id: U5WR01
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS05360
gene id: 557599:MKAN_RS05360
uniprot id: U5WPG7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

557599:MKAN RS26025
gene id: 557599:MKAN_RS26025
uniprot id: U5WWK9
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS12705
gene id: 557599:MKAN_RS12705
uniprot id: U5WSX0
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

557599:MKAN RS16120
gene id: 557599:MKAN_RS16120
uniprot id: U5WRI3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

557599:MKAN RS01720
gene id: 557599:MKAN_RS01720
uniprot id: U5WJ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

557599:MKAN RS01485
gene id: 557599:MKAN_RS01485
uniprot id: U5WJ22
names: Similarity
messages: Belongs to the TPP enzyme family.

557599:MKAN RS02760
gene id: 557599:MKAN_RS02760
uniprot id: U5WN47
names: Similarity
messages: Belongs to the peptidase C40 family.

557599:MKAN RS26490
gene id: 557599:MKAN_RS26490
uniprot id: U5X041
names: Similarity
messages: Belongs to the peptidase C40 family.

557599:MKAN RS04690
gene id: 557599:MKAN_RS04690
uniprot id: U5WP69
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS08005
gene id: 557599:MKAN_RS08005
uniprot id: U5WM49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

557599:MKAN RS02700
gene id: 557599:MKAN_RS02700
uniprot id: U5WJK0
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

557599:MKAN RS13450
gene id: 557599:MKAN_RS13450
uniprot id: U5WPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS15760
gene id: 557599:MKAN_RS15760
uniprot id: U5WUW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

557599:MKAN RS17630
gene id: 557599:MKAN_RS17630
uniprot id: U5WSD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS00465
gene id: 557599:MKAN_RS00465
uniprot id: U5WLX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

557599:MKAN RS23580
gene id: 557599:MKAN_RS23580
uniprot id: U5WW32
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

557599:MKAN RS22365
gene id: 557599:MKAN_RS22365
uniprot id: U5WVE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS15470
gene id: 557599:MKAN_RS15470
uniprot id: U5WRV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS10635
gene id: 557599:MKAN_RS10635
uniprot id: U5WNF8
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS25535
gene id: 557599:MKAN_RS25535
uniprot id: U5WX30
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

557599:MKAN RS05875
gene id: 557599:MKAN_RS05875
uniprot id: U5WPQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

557599:MKAN RS12250
gene id: 557599:MKAN_RS12250
uniprot id: U5WPJ5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

557599:MKAN RS08090
gene id: 557599:MKAN_RS08090
uniprot id: U5WQI5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

557599:MKAN RS00095
gene id: 557599:MKAN_RS00095
uniprot id: U5WIR8
names: Similarity
messages: Belongs to the DAPG/phloretin hydrolase family.

557599:MKAN RS18835
gene id: 557599:MKAN_RS18835
uniprot id: U5WSR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

557599:MKAN RS00420
gene id: 557599:MKAN_RS00420
uniprot id: U5WIB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

557599:MKAN RS21195
gene id: 557599:MKAN_RS21195
uniprot id: U5WUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS25505
gene id: 557599:MKAN_RS25505
uniprot id: U5X008
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

557599:MKAN RS22245
gene id: 557599:MKAN_RS22245
uniprot id: U5WXW6
names: Similarity
messages: Belongs to the DNA photolyase family.

557599:MKAN RS10745
gene id: 557599:MKAN_RS10745
uniprot id: U5WRT4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS07525
gene id: 557599:MKAN_RS07525
uniprot id: U5WMN6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

557599:MKAN RS05230
gene id: 557599:MKAN_RS05230
uniprot id: U5WKV3
names: Similarity
messages: Belongs to the FPG family.

557599:MKAN RS07595
gene id: 557599:MKAN_RS07595
uniprot id: U5WQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

557599:MKAN RS22310
gene id: 557599:MKAN_RS22310
uniprot id: U5WVD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

557599:MKAN RS26360
gene id: 557599:MKAN_RS26360
uniprot id: U5X019
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

557599:MKAN RS22915
gene id: 557599:MKAN_RS22915
uniprot id: U5WUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

557599:MKAN RS15375
gene id: 557599:MKAN_RS15375
uniprot id: U5WRT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

557599:MKAN RS19865
gene id: 557599:MKAN_RS19865
uniprot id: U5WTI6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS04240
gene id: 557599:MKAN_RS04240
uniprot id: U5WP02
names: Similarity
messages: Belongs to the HepT RNase toxin family.

557599:MKAN RS22120
gene id: 557599:MKAN_RS22120
uniprot id: U5WY60
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

557599:MKAN RS12260
gene id: 557599:MKAN_RS12260
uniprot id: U5WT62
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

557599:MKAN RS22830
gene id: 557599:MKAN_RS22830
uniprot id: U5WVN4
names: Similarity
messages: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily.

557599:MKAN RS21745
gene id: 557599:MKAN_RS21745
uniprot id: U5WY12
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS25680
gene id: 557599:MKAN_RS25680
uniprot id: U5WX57
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS23995
gene id: 557599:MKAN_RS23995
uniprot id: U5WWB0
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS15860
gene id: 557599:MKAN_RS15860
uniprot id: U5WRD7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS18870
gene id: 557599:MKAN_RS18870
uniprot id: U5X2D0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

557599:MKAN RS07995
gene id: 557599:MKAN_RS07995
uniprot id: U5WQV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

557599:MKAN RS22445
gene id: 557599:MKAN_RS22445
uniprot id: U5WVG0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS13705
gene id: 557599:MKAN_RS13705
uniprot id: U5WTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

557599:MKAN RS05960
gene id: 557599:MKAN_RS05960
uniprot id: U5WLS2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

557599:MKAN RS08730
gene id: 557599:MKAN_RS08730
uniprot id: U5WR87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

557599:MKAN RS14655
gene id: 557599:MKAN_RS14655
uniprot id: U5WU91
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS27075
gene id: 557599:MKAN_RS27075
uniprot id: U5WX12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS21130
gene id: 557599:MKAN_RS21130
uniprot id: U5WU83
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS16215
gene id: 557599:MKAN_RS16215
uniprot id: U5WS81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

557599:MKAN RS23215
gene id: 557599:MKAN_RS23215
uniprot id: U5WYI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

557599:MKAN RS05780
gene id: 557599:MKAN_RS05780
uniprot id: U5WPA8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS02350
gene id: 557599:MKAN_RS02350
uniprot id: U5WJE2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS06010
gene id: 557599:MKAN_RS06010
uniprot id: U5WLT2
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

557599:MKAN RS05995
gene id: 557599:MKAN_RS05995
uniprot id: U5WL89
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

557599:MKAN RS10190
gene id: 557599:MKAN_RS10190
uniprot id: U5WN98
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

557599:MKAN RS05885
gene id: 557599:MKAN_RS05885
uniprot id: U5WL11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

557599:MKAN RS22380
gene id: 557599:MKAN_RS22380
uniprot id: U5WUV1
names: Subcellular Location Annotation
messages: Secreted

557599:MKAN RS17340
gene id: 557599:MKAN_RS17340
uniprot id: U5WS49
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS17485
gene id: 557599:MKAN_RS17485
uniprot id: U5WVD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS28530
gene id: 557599:MKAN_RS28530
uniprot id: U5WLF4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS11680
gene id: 557599:MKAN_RS11680
uniprot id: U5WNY0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

557599:MKAN RS26655
gene id: 557599:MKAN_RS26655
uniprot id: U5X061
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

557599:MKAN RS01745
gene id: 557599:MKAN_RS01745
uniprot id: U5WJ61
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS00075
gene id: 557599:MKAN_RS00075
uniprot id: U5WI43
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS09970
gene id: 557599:MKAN_RS09970
uniprot id: U5WN73
names: Function
names: Subunit
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

557599:MKAN RS14470
gene id: 557599:MKAN_RS14470
uniprot id: U5WR80
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS27620
gene id: 557599:MKAN_RS27620
uniprot id: U5X0M1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS27570
gene id: 557599:MKAN_RS27570
uniprot id: U5X0L1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS08305
gene id: 557599:MKAN_RS08305
uniprot id: U5WQM5
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS17375
gene id: 557599:MKAN_RS17375
uniprot id: U5WVA6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS17110
gene id: 557599:MKAN_RS17110
uniprot id: U5WRU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

557599:MKAN RS21475
gene id: 557599:MKAN_RS21475
uniprot id: U5WV02
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

557599:MKAN RS00815
gene id: 557599:MKAN_RS00815
uniprot id: U5WIJ3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS11965
gene id: 557599:MKAN_RS11965
uniprot id: U5WSW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

557599:MKAN RS08585
gene id: 557599:MKAN_RS08585
uniprot id: U5WQS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

557599:MKAN RS26685
gene id: 557599:MKAN_RS26685
uniprot id: U5X0N0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

557599:MKAN RS11450
gene id: 557599:MKAN_RS11450
uniprot id: U5WS61
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS19000
gene id: 557599:MKAN_RS19000
uniprot id: U5WW86
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS01790
gene id: 557599:MKAN_RS01790
uniprot id: U5WJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS17595
gene id: 557599:MKAN_RS17595
uniprot id: U5WT05
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS03135
gene id: 557599:MKAN_RS03135
uniprot id: U5WMZ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS06895
gene id: 557599:MKAN_RS06895
uniprot id: U5WQD0
names: Cofactor
messages: Binds 1 FAD per subunit.

557599:MKAN RS22150
gene id: 557599:MKAN_RS22150
uniprot id: U5WVA5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

557599:MKAN RS25390
gene id: 557599:MKAN_RS25390
uniprot id: U5WZI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

557599:MKAN RS22520
gene id: 557599:MKAN_RS22520
uniprot id: U5WVH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

557599:MKAN RS01505
gene id: 557599:MKAN_RS01505
uniprot id: U5WIZ1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

557599:MKAN RS19115
gene id: 557599:MKAN_RS19115
uniprot id: U5WWM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

557599:MKAN RS04660
gene id: 557599:MKAN_RS04660
uniprot id: U5WP67
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

557599:MKAN RS14945
gene id: 557599:MKAN_RS14945
uniprot id: U5X267
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS21260
gene id: 557599:MKAN_RS21260
uniprot id: U5WUA7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS04600
gene id: 557599:MKAN_RS04600
uniprot id: U5WKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

557599:MKAN RS03480
gene id: 557599:MKAN_RS03480
uniprot id: U5WKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane

557599:MKAN RS17800
gene id: 557599:MKAN_RS17800
uniprot id: U5WT37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS25140
gene id: 557599:MKAN_RS25140
uniprot id: U5WWV7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS17240
gene id: 557599:MKAN_RS17240
uniprot id: U5WV84
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

557599:MKAN RS08525
gene id: 557599:MKAN_RS08525
uniprot id: U5WMC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

557599:MKAN RS10580
gene id: 557599:MKAN_RS10580
uniprot id: U5WZ14
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

557599:MKAN RS16240
gene id: 557599:MKAN_RS16240
uniprot id: U5WS86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

557599:MKAN RS19120
gene id: 557599:MKAN_RS19120
uniprot id: U5WTR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

557599:MKAN RS22075
gene id: 557599:MKAN_RS22075
uniprot id: U5WV92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS02815
gene id: 557599:MKAN_RS02815
uniprot id: U5WMU2
names: Similarity
messages: Belongs to the MmpS family.

557599:MKAN RS02570
gene id: 557599:MKAN_RS02570
uniprot id: U5WJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

557599:MKAN RS05825
gene id: 557599:MKAN_RS05825
uniprot id: U5WL01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS17640
gene id: 557599:MKAN_RS17640
uniprot id: U5WVY1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

557599:MKAN RS09845
gene id: 557599:MKAN_RS09845
uniprot id: U5WN54
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS16645
gene id: 557599:MKAN_RS16645
uniprot id: U5WRR2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

557599:MKAN RS27000
gene id: 557599:MKAN_RS27000
uniprot id: U5WXU7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS15945
gene id: 557599:MKAN_RS15945
uniprot id: U5WS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Cell membrane

557599:MKAN RS01390
gene id: 557599:MKAN_RS01390
uniprot id: U5WMI7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS21370
gene id: 557599:MKAN_RS21370
uniprot id: U5WXU9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

557599:MKAN RS25410
gene id: 557599:MKAN_RS25410
uniprot id: U5WWF5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

557599:MKAN RS19940
gene id: 557599:MKAN_RS19940
uniprot id: U5WTB7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

557599:MKAN RS05945
gene id: 557599:MKAN_RS05945
uniprot id: U5WL78
names: Similarity
messages: Belongs to the peptidase S58 family.

557599:MKAN RS10575
gene id: 557599:MKAN_RS10575
uniprot id: U5WNL4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

557599:MKAN RS06390
gene id: 557599:MKAN_RS06390
uniprot id: U5WPL2
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS01545
gene id: 557599:MKAN_RS01545
uniprot id: U5WML5
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

557599:MKAN RS09785
gene id: 557599:MKAN_RS09785
uniprot id: U5WRX3
names: Function
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.
messages: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).

557599:MKAN RS12120
gene id: 557599:MKAN_RS12120
uniprot id: U5WP70
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS06735
gene id: 557599:MKAN_RS06735
uniprot id: U5WQA2
names: Similarity
messages: Belongs to the LOG family.

557599:MKAN RS04820
gene id: 557599:MKAN_RS04820
uniprot id: U5WKJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

557599:MKAN RS14210
gene id: 557599:MKAN_RS14210
uniprot id: U5WR33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CwsA family.
messages: Cell membrane
messages: Required for regulated cell division, cell wall synthesis and the maintenance of cell shape.

557599:MKAN RS01240
gene id: 557599:MKAN_RS01240
uniprot id: U5WIY8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS04910
gene id: 557599:MKAN_RS04910
uniprot id: U5WKQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS14480
gene id: 557599:MKAN_RS14480
uniprot id: U5WQL7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

557599:MKAN RS01710
gene id: 557599:MKAN_RS01710
uniprot id: U5WJM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS04400
gene id: 557599:MKAN_RS04400
uniprot id: U5WNP0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS20305
gene id: 557599:MKAN_RS20305
uniprot id: U5WUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

557599:MKAN RS18970
gene id: 557599:MKAN_RS18970
uniprot id: U5WT08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

557599:MKAN RS16210
gene id: 557599:MKAN_RS16210
uniprot id: U5WV44
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS16700
gene id: 557599:MKAN_RS16700
uniprot id: U5WSG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

557599:MKAN RS25365
gene id: 557599:MKAN_RS25365
uniprot id: U5WZH9
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
messages: Homodimer.

557599:MKAN RS05830
gene id: 557599:MKAN_RS05830
uniprot id: U5WL58
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS23550
gene id: 557599:MKAN_RS23550
uniprot id: U5WZ34
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

557599:MKAN RS00165
gene id: 557599:MKAN_RS00165
uniprot id: U5WLS0
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS21675
gene id: 557599:MKAN_RS21675
uniprot id: U5WUH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS06920
gene id: 557599:MKAN_RS06920
uniprot id: U5WQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

557599:MKAN RS31520
gene id: 557599:MKAN_RS31520
uniprot id: U5X057
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS19945
gene id: 557599:MKAN_RS19945
uniprot id: U5WTJ9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

557599:MKAN RS13100
gene id: 557599:MKAN_RS13100
uniprot id: U5WPR8
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS14820
gene id: 557599:MKAN_RS14820
uniprot id: U5WQM8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

557599:MKAN RS22495
gene id: 557599:MKAN_RS22495
uniprot id: U5WVH1
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS06565
gene id: 557599:MKAN_RS06565
uniprot id: U5WLI9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

557599:MKAN RS19560
gene id: 557599:MKAN_RS19560
uniprot id: U5WTC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS19310
gene id: 557599:MKAN_RS19310
uniprot id: U5WWD9
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS19520
gene id: 557599:MKAN_RS19520
uniprot id: U5WWV0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

557599:MKAN RS18460
gene id: 557599:MKAN_RS18460
uniprot id: U5WSK6
names: Similarity
messages: Belongs to the UPF0336 family.

557599:MKAN RS00040
gene id: 557599:MKAN_RS00040
uniprot id: U5WLP6
names: Similarity
messages: Belongs to the CsoR family.

557599:MKAN RS11340
gene id: 557599:MKAN_RS11340
uniprot id: U5WS43
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS21190
gene id: 557599:MKAN_RS21190
uniprot id: U5WXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS14010
gene id: 557599:MKAN_RS14010
uniprot id: U5WQ71
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS18040
gene id: 557599:MKAN_RS18040
uniprot id: U5WT75
names: Similarity
messages: Belongs to the UPF0234 family.

557599:MKAN RS19255
gene id: 557599:MKAN_RS19255
uniprot id: U5WT60
names: Similarity
messages: Belongs to the group II decarboxylase family.

557599:MKAN RS17210
gene id: 557599:MKAN_RS17210
uniprot id: U5WV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

557599:MKAN RS04790
gene id: 557599:MKAN_RS04790
uniprot id: U5WKP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

557599:MKAN RS16465
gene id: 557599:MKAN_RS16465
uniprot id: U5WSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

557599:MKAN RS14535
gene id: 557599:MKAN_RS14535
uniprot id: U5WR89
names: Similarity
messages: Belongs to the Nudix hydrolase family.

557599:MKAN RS23190
gene id: 557599:MKAN_RS23190
uniprot id: U5WYH6
names: Similarity
messages: Belongs to the UPF0102 family.

557599:MKAN RS10685
gene id: 557599:MKAN_RS10685
uniprot id: U5WS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

557599:MKAN RS11045
gene id: 557599:MKAN_RS11045
uniprot id: U5WNL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

557599:MKAN RS04425
gene id: 557599:MKAN_RS04425
uniprot id: U5WNP3
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

557599:MKAN RS08110
gene id: 557599:MKAN_RS08110
uniprot id: U5WM64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

557599:MKAN RS04560
gene id: 557599:MKAN_RS04560
uniprot id: U5WP48
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS19210
gene id: 557599:MKAN_RS19210
uniprot id: U5WWC4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

557599:MKAN RS13770
gene id: 557599:MKAN_RS13770
uniprot id: U5WQ32
names: Similarity
messages: Belongs to the glutamate synthase family.

557599:MKAN RS04180
gene id: 557599:MKAN_RS04180
uniprot id: U5WKX9
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS02290
gene id: 557599:MKAN_RS02290
uniprot id: U5WJW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

557599:MKAN RS16665
gene id: 557599:MKAN_RS16665
uniprot id: U5WVB6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

557599:MKAN RS10385
gene id: 557599:MKAN_RS10385
uniprot id: U5WP62
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

557599:MKAN RS27015
gene id: 557599:MKAN_RS27015
uniprot id: U5X0B6
names: Similarity
messages: Belongs to the UPF0434 family.

557599:MKAN RS19410
gene id: 557599:MKAN_RS19410
uniprot id: U5WT93
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

557599:MKAN RS17725
gene id: 557599:MKAN_RS17725
uniprot id: U5WSG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS02895
gene id: 557599:MKAN_RS02895
uniprot id: U5WN70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

557599:MKAN RS07615
gene id: 557599:MKAN_RS07615
uniprot id: U5WM48
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

557599:MKAN RS07870
gene id: 557599:MKAN_RS07870
uniprot id: U5WM30
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS18380
gene id: 557599:MKAN_RS18380
uniprot id: U5WSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS14420
gene id: 557599:MKAN_RS14420
uniprot id: U5WQE7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS17260
gene id: 557599:MKAN_RS17260
uniprot id: U5WS35
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS03540
gene id: 557599:MKAN_RS03540
uniprot id: U5WJZ2
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS24965
gene id: 557599:MKAN_RS24965
uniprot id: U5WVW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

557599:MKAN RS26400
gene id: 557599:MKAN_RS26400
uniprot id: U5WWR1
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

557599:MKAN RS22985
gene id: 557599:MKAN_RS22985
uniprot id: U5WVR8
names: Similarity
messages: Belongs to the acylphosphatase family.

557599:MKAN RS02680
gene id: 557599:MKAN_RS02680
uniprot id: U5WMR8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

557599:MKAN RS04705
gene id: 557599:MKAN_RS04705
uniprot id: U5WKH7
names: Similarity
messages: Belongs to the thioesterase family.

557599:MKAN RS16930
gene id: 557599:MKAN_RS16930
uniprot id: U5WRW7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS19400
gene id: 557599:MKAN_RS19400
uniprot id: U5WTW2
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

557599:MKAN RS26020
gene id: 557599:MKAN_RS26020
uniprot id: U5WXC9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

557599:MKAN RS24355
gene id: 557599:MKAN_RS24355
uniprot id: U5WVW7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS19385
gene id: 557599:MKAN_RS19385
uniprot id: U5WT88
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

557599:MKAN RS23225
gene id: 557599:MKAN_RS23225
uniprot id: U5WVW9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

557599:MKAN RS18765
gene id: 557599:MKAN_RS18765
uniprot id: U5WSX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

557599:MKAN RS13110
gene id: 557599:MKAN_RS13110
uniprot id: U5WT28
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS16440
gene id: 557599:MKAN_RS16440
uniprot id: U5WSB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

557599:MKAN RS22600
gene id: 557599:MKAN_RS22600
uniprot id: U5WYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

557599:MKAN RS11440
gene id: 557599:MKAN_RS11440
uniprot id: U5WNT2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS28110
gene id: 557599:MKAN_RS28110
uniprot id: U5X367
names: Similarity
messages: Belongs to the EccE family.

557599:MKAN RS21670
gene id: 557599:MKAN_RS21670
uniprot id: U5WU88
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS19170
gene id: 557599:MKAN_RS19170
uniprot id: U5WTS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS21715
gene id: 557599:MKAN_RS21715
uniprot id: U5WY07
names: Similarity
messages: Belongs to the UPF0166 family.

557599:MKAN RS17250
gene id: 557599:MKAN_RS17250
uniprot id: U5WSR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

557599:MKAN RS26585
gene id: 557599:MKAN_RS26585
uniprot id: U5WX44
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

557599:MKAN RS17490
gene id: 557599:MKAN_RS17490
uniprot id: U5WVR7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

557599:MKAN RS24185
gene id: 557599:MKAN_RS24185
uniprot id: U5WYX7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

557599:MKAN RS26650
gene id: 557599:MKAN_RS26650
uniprot id: U5WX53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

557599:MKAN RS02960
gene id: 557599:MKAN_RS02960
uniprot id: U5WJQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

557599:MKAN RS19175
gene id: 557599:MKAN_RS19175
uniprot id: U5WSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

557599:MKAN RS11345
gene id: 557599:MKAN_RS11345
uniprot id: U5WSJ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS01530
gene id: 557599:MKAN_RS01530
uniprot id: U5WIZ5
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS14045
gene id: 557599:MKAN_RS14045
uniprot id: U5WTJ3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS09120
gene id: 557599:MKAN_RS09120
uniprot id: U5WR03
names: Similarity
messages: Belongs to the MoaD family.

557599:MKAN RS19525
gene id: 557599:MKAN_RS19525
uniprot id: U5WTY9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

557599:MKAN RS27235
gene id: 557599:MKAN_RS27235
uniprot id: U5X0F7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

557599:MKAN RS21830
gene id: 557599:MKAN_RS21830
uniprot id: U5WUB1
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS25115
gene id: 557599:MKAN_RS25115
uniprot id: U5WWV2
names: Similarity
messages: Belongs to the DapA family.

557599:MKAN RS10935
gene id: 557599:MKAN_RS10935
uniprot id: U5WRW3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

557599:MKAN RS26985
gene id: 557599:MKAN_RS26985
uniprot id: U5WXA1
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
messages: Homodimer.

557599:MKAN RS22125
gene id: 557599:MKAN_RS22125
uniprot id: U5WVA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

557599:MKAN RS25695
gene id: 557599:MKAN_RS25695
uniprot id: U5WZN8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS22610
gene id: 557599:MKAN_RS22610
uniprot id: U5WUP8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

557599:MKAN RS02635
gene id: 557599:MKAN_RS02635
uniprot id: U5WN23
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS03445
gene id: 557599:MKAN_RS03445
uniprot id: U5WN49
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS05925
gene id: 557599:MKAN_RS05925
uniprot id: U5WPD0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS22770
gene id: 557599:MKAN_RS22770
uniprot id: U5WVM3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS06820
gene id: 557599:MKAN_RS06820
uniprot id: U5WQB7
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

557599:MKAN RS07125
gene id: 557599:MKAN_RS07125
uniprot id: U5WQ30
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS00185
gene id: 557599:MKAN_RS00185
uniprot id: U5WLH2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS06750
gene id: 557599:MKAN_RS06750
uniprot id: U5WLR0
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS25400
gene id: 557599:MKAN_RS25400
uniprot id: U5WX02
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

557599:MKAN RS14490
gene id: 557599:MKAN_RS14490
uniprot id: U5WTR8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

557599:MKAN RS24560
gene id: 557599:MKAN_RS24560
uniprot id: U5WWJ7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

557599:MKAN RS25965
gene id: 557599:MKAN_RS25965
uniprot id: U5WXB9
names: Similarity
messages: Belongs to the peptidase C40 family.

557599:MKAN RS03645
gene id: 557599:MKAN_RS03645
uniprot id: U5WK07
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS21505
gene id: 557599:MKAN_RS21505
uniprot id: U5WV06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

557599:MKAN RS11860
gene id: 557599:MKAN_RS11860
uniprot id: U5WSU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

557599:MKAN RS04915
gene id: 557599:MKAN_RS04915
uniprot id: U5WNW1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS25065
gene id: 557599:MKAN_RS25065
uniprot id: U5WWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

557599:MKAN RS21905
gene id: 557599:MKAN_RS21905
uniprot id: U5WUC1
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS23435
gene id: 557599:MKAN_RS23435
uniprot id: U5WV82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

557599:MKAN RS13945
gene id: 557599:MKAN_RS13945
uniprot id: U5WQY6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS06630
gene id: 557599:MKAN_RS06630
uniprot id: U5WQ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

557599:MKAN RS15070
gene id: 557599:MKAN_RS15070
uniprot id: U5WQV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

557599:MKAN RS01795
gene id: 557599:MKAN_RS01795
uniprot id: U5WJ32
names: Similarity
messages: Belongs to the MmpS family.

557599:MKAN RS05600
gene id: 557599:MKAN_RS05600
uniprot id: U5X170
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS10160
gene id: 557599:MKAN_RS10160
uniprot id: U5WP24
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS27730
gene id: 557599:MKAN_RS27730
uniprot id: U5X140
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS03750
gene id: 557599:MKAN_RS03750
uniprot id: U5WNN0
names: Similarity
messages: Belongs to the ClpX chaperone family.

557599:MKAN RS07265
gene id: 557599:MKAN_RS07265
uniprot id: U5WLZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

557599:MKAN RS20115
gene id: 557599:MKAN_RS20115
uniprot id: U5WTM8
names: Similarity
messages: Belongs to the AccD/PCCB family.

557599:MKAN RS24135
gene id: 557599:MKAN_RS24135
uniprot id: U5WYW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

557599:MKAN RS23675
gene id: 557599:MKAN_RS23675
uniprot id: U5WYP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

557599:MKAN RS20385
gene id: 557599:MKAN_RS20385
uniprot id: U5WTP7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

557599:MKAN RS18845
gene id: 557599:MKAN_RS18845
uniprot id: U5WW59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

557599:MKAN RS18830
gene id: 557599:MKAN_RS18830
uniprot id: U5WTL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

557599:MKAN RS06835
gene id: 557599:MKAN_RS06835
uniprot id: U5WLS7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS01800
gene id: 557599:MKAN_RS01800
uniprot id: U5WJ69
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

557599:MKAN RS10035
gene id: 557599:MKAN_RS10035
uniprot id: U5WN81
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS00860
gene id: 557599:MKAN_RS00860
uniprot id: U5WM47
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS24555
gene id: 557599:MKAN_RS24555
uniprot id: U5X2Q1
names: Similarity
messages: Belongs to the TPP enzyme family.

557599:MKAN RS05190
gene id: 557599:MKAN_RS05190
uniprot id: U5WKQ5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

557599:MKAN RS17230
gene id: 557599:MKAN_RS17230
uniprot id: U5WRW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS02065
gene id: 557599:MKAN_RS02065
uniprot id: U5WJ63
names: Similarity
messages: Belongs to the peptidase M24B family.

557599:MKAN RS25850
gene id: 557599:MKAN_RS25850
uniprot id: U5WWS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

557599:MKAN RS13695
gene id: 557599:MKAN_RS13695
uniprot id: U5WQ69
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

557599:MKAN RS14580
gene id: 557599:MKAN_RS14580
uniprot id: U5WTT2
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

557599:MKAN RS14285
gene id: 557599:MKAN_RS14285
uniprot id: U5WTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS19295
gene id: 557599:MKAN_RS19295
uniprot id: U5WTU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

557599:MKAN RS26915
gene id: 557599:MKAN_RS26915
uniprot id: U5X0R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

557599:MKAN RS22165
gene id: 557599:MKAN_RS22165
uniprot id: U5WXV4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS25625
gene id: 557599:MKAN_RS25625
uniprot id: U5X025
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS09035
gene id: 557599:MKAN_RS09035
uniprot id: U5WMU1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

557599:MKAN RS06745
gene id: 557599:MKAN_RS06745
uniprot id: U5WLK6
names: Similarity
messages: Belongs to the EccE family.

557599:MKAN RS21365
gene id: 557599:MKAN_RS21365
uniprot id: U5WXH4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

557599:MKAN RS25780
gene id: 557599:MKAN_RS25780
uniprot id: U5X082
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

557599:MKAN RS14550
gene id: 557599:MKAN_RS14550
uniprot id: U5WTS7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS10645
gene id: 557599:MKAN_RS10645
uniprot id: U5WRR7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

557599:MKAN RS13200
gene id: 557599:MKAN_RS13200
uniprot id: U5WQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

557599:MKAN RS07590
gene id: 557599:MKAN_RS07590
uniprot id: U5WM44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

557599:MKAN RS10215
gene id: 557599:MKAN_RS10215
uniprot id: U5WNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

557599:MKAN RS25255
gene id: 557599:MKAN_RS25255
uniprot id: U5WZG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

557599:MKAN RS01555
gene id: 557599:MKAN_RS01555
uniprot id: U5WJ00
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

557599:MKAN RS26210
gene id: 557599:MKAN_RS26210
uniprot id: U5WWN5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

557599:MKAN RS23410
gene id: 557599:MKAN_RS23410
uniprot id: U5WV79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

557599:MKAN RS19710
gene id: 557599:MKAN_RS19710
uniprot id: U5WTG0
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS10665
gene id: 557599:MKAN_RS10665
uniprot id: U5WNG2
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

557599:MKAN RS20135
gene id: 557599:MKAN_RS20135
uniprot id: U5WTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

557599:MKAN RS14100
gene id: 557599:MKAN_RS14100
uniprot id: U5WTZ6
names: Similarity
messages: Belongs to the ParB family.

557599:MKAN RS00505
gene id: 557599:MKAN_RS00505
uniprot id: U5WID0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

557599:MKAN RS22255
gene id: 557599:MKAN_RS22255
uniprot id: U5WVC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS24845
gene id: 557599:MKAN_RS24845
uniprot id: U5WZ84
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS11665
gene id: 557599:MKAN_RS11665
uniprot id: U5WS97
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

557599:MKAN RS06810
gene id: 557599:MKAN_RS06810
uniprot id: U5WLR9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS26405
gene id: 557599:MKAN_RS26405
uniprot id: U5WX11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS06115
gene id: 557599:MKAN_RS06115
uniprot id: U5WPG1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

557599:MKAN RS04075
gene id: 557599:MKAN_RS04075
uniprot id: U5WNX8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

557599:MKAN RS01780
gene id: 557599:MKAN_RS01780
uniprot id: U5WMC5
names: Similarity
messages: Belongs to the CobH/CbiC family.

557599:MKAN RS16640
gene id: 557599:MKAN_RS16640
uniprot id: U5WRL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

557599:MKAN RS18925
gene id: 557599:MKAN_RS18925
uniprot id: U5WW72
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

557599:MKAN RS04500
gene id: 557599:MKAN_RS04500
uniprot id: U5WKJ5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

557599:MKAN RS22910
gene id: 557599:MKAN_RS22910
uniprot id: U5WVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

557599:MKAN RS09440
gene id: 557599:MKAN_RS09440
uniprot id: U5WRR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

557599:MKAN RS23125
gene id: 557599:MKAN_RS23125
uniprot id: U5WVV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

557599:MKAN RS25775
gene id: 557599:MKAN_RS25775
uniprot id: U5WZT2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS06550
gene id: 557599:MKAN_RS06550
uniprot id: U5WQ29
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.

557599:MKAN RS26270
gene id: 557599:MKAN_RS26270
uniprot id: U5WWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS22030
gene id: 557599:MKAN_RS22030
uniprot id: U5WUD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS21405
gene id: 557599:MKAN_RS21405
uniprot id: U5WU43
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS26000
gene id: 557599:MKAN_RS26000
uniprot id: U5WWK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

557599:MKAN RS26005
gene id: 557599:MKAN_RS26005
uniprot id: U5WWV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS22685
gene id: 557599:MKAN_RS22685
uniprot id: U5WVK4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

557599:MKAN RS02580
gene id: 557599:MKAN_RS02580
uniprot id: U5WMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

557599:MKAN RS04105
gene id: 557599:MKAN_RS04105
uniprot id: U5WKW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

557599:MKAN RS18100
gene id: 557599:MKAN_RS18100
uniprot id: U5WT86
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS08930
gene id: 557599:MKAN_RS08930
uniprot id: U5WQX0
names: Similarity
messages: Belongs to the AccD/PCCB family.

557599:MKAN RS16745
gene id: 557599:MKAN_RS16745
uniprot id: U5WVD1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

557599:MKAN RS14500
gene id: 557599:MKAN_RS14500
uniprot id: U5WR85
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS10205
gene id: 557599:MKAN_RS10205
uniprot id: U5WS28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

557599:MKAN RS05395
gene id: 557599:MKAN_RS05395
uniprot id: U5WKT1
names: Similarity
messages: Belongs to the AccD/PCCB family.

557599:MKAN RS08485
gene id: 557599:MKAN_RS08485
uniprot id: U5WR47
names: Similarity
messages: Belongs to the AccD/PCCB family.

557599:MKAN RS00805
gene id: 557599:MKAN_RS00805
uniprot id: U5WM37
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

557599:MKAN RS03420
gene id: 557599:MKAN_RS03420
uniprot id: U5WN44
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS25085
gene id: 557599:MKAN_RS25085
uniprot id: U5WZT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS00335
gene id: 557599:MKAN_RS00335
uniprot id: U5WIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

557599:MKAN RS17120
gene id: 557599:MKAN_RS17120
uniprot id: U5WV67
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

557599:MKAN RS04575
gene id: 557599:MKAN_RS04575
uniprot id: U5WKK7
names: Similarity
messages: Belongs to the Fur family.

557599:MKAN RS05695
gene id: 557599:MKAN_RS05695
uniprot id: U5WPM4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS08125
gene id: 557599:MKAN_RS08125
uniprot id: U5WQX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

557599:MKAN RS20090
gene id: 557599:MKAN_RS20090
uniprot id: U5WTM1
names: Similarity
messages: Belongs to the SufE family.

557599:MKAN RS28145
gene id: 557599:MKAN_RS28145
uniprot id: U5WZI4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS12610
gene id: 557599:MKAN_RS12610
uniprot id: U5WTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

557599:MKAN RS16680
gene id: 557599:MKAN_RS16680
uniprot id: U5WRR8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS01190
gene id: 557599:MKAN_RS01190
uniprot id: U5WIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

557599:MKAN RS07295
gene id: 557599:MKAN_RS07295
uniprot id: U5WQ53
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS23955
gene id: 557599:MKAN_RS23955
uniprot id: U5WYT7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

557599:MKAN RS07710
gene id: 557599:MKAN_RS07710
uniprot id: U5WQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

557599:MKAN RS00755
gene id: 557599:MKAN_RS00755
uniprot id: U5WM25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS05615
gene id: 557599:MKAN_RS05615
uniprot id: U5WPK9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS19745
gene id: 557599:MKAN_RS19745
uniprot id: U5WWZ1
names: Similarity
messages: Belongs to the peptidase S11 family.

557599:MKAN RS22095
gene id: 557599:MKAN_RS22095
uniprot id: U5WY56
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS18960
gene id: 557599:MKAN_RS18960
uniprot id: U5WTN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

557599:MKAN RS23115
gene id: 557599:MKAN_RS23115
uniprot id: U5WYG0
names: Similarity
messages: Belongs to the peptidase S11 family.

557599:MKAN RS00210
gene id: 557599:MKAN_RS00210
uniprot id: U5WLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

557599:MKAN RS20325
gene id: 557599:MKAN_RS20325
uniprot id: U5WXD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

557599:MKAN RS26390
gene id: 557599:MKAN_RS26390
uniprot id: U5X0I3
names: Similarity
messages: Belongs to the YciI family.

557599:MKAN RS23660
gene id: 557599:MKAN_RS23660
uniprot id: U5WVB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

557599:MKAN RS13465
gene id: 557599:MKAN_RS13465
uniprot id: U5WTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS25985
gene id: 557599:MKAN_RS25985
uniprot id: U5X0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0353 family.
messages: Cell membrane

557599:MKAN RS02655
gene id: 557599:MKAN_RS02655
uniprot id: U5WMR3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

557599:MKAN RS24580
gene id: 557599:MKAN_RS24580
uniprot id: U5WZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS23720
gene id: 557599:MKAN_RS23720
uniprot id: U5WVL1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS22180
gene id: 557599:MKAN_RS22180
uniprot id: U5WUG0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS05850
gene id: 557599:MKAN_RS05850
uniprot id: U5WL06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS05310
gene id: 557599:MKAN_RS05310
uniprot id: U5WKS0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

557599:MKAN RS07330
gene id: 557599:MKAN_RS07330
uniprot id: U5WMK3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS00285
gene id: 557599:MKAN_RS00285
uniprot id: U5WIC9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS16430
gene id: 557599:MKAN_RS16430
uniprot id: U5WUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

557599:MKAN RS03180
gene id: 557599:MKAN_RS03180
uniprot id: U5WJU3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS21180
gene id: 557599:MKAN_RS21180
uniprot id: U5WU92
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

557599:MKAN RS11550
gene id: 557599:MKAN_RS11550
uniprot id: U5WP26
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

557599:MKAN RS21185
gene id: 557599:MKAN_RS21185
uniprot id: U5WXE0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

557599:MKAN RS01220
gene id: 557599:MKAN_RS01220
uniprot id: U5WM50
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS01330
gene id: 557599:MKAN_RS01330
uniprot id: U5WM65
names: Similarity
messages: Belongs to the fructosamine kinase family.

557599:MKAN RS17965
gene id: 557599:MKAN_RS17965
uniprot id: U5WSK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

557599:MKAN RS06640
gene id: 557599:MKAN_RS06640
uniprot id: U5WLH7
names: Similarity
messages: Belongs to the peptidase S1C family.

557599:MKAN RS19735
gene id: 557599:MKAN_RS19735
uniprot id: U5WTG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

557599:MKAN RS08880
gene id: 557599:MKAN_RS08880
uniprot id: U5WQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

557599:MKAN RS06385
gene id: 557599:MKAN_RS06385
uniprot id: U5WLG1
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS18735
gene id: 557599:MKAN_RS18735
uniprot id: U5WSX3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS23155
gene id: 557599:MKAN_RS23155
uniprot id: U5WV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

557599:MKAN RS10690
gene id: 557599:MKAN_RS10690
uniprot id: U5WPA5
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS12815
gene id: 557599:MKAN_RS12815
uniprot id: U5WQE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

557599:MKAN RS19195
gene id: 557599:MKAN_RS19195
uniprot id: U5WTS6
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS26545
gene id: 557599:MKAN_RS26545
uniprot id: U5X0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

557599:MKAN RS25270
gene id: 557599:MKAN_RS25270
uniprot id: U5WW29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

557599:MKAN RS23000
gene id: 557599:MKAN_RS23000
uniprot id: U5WYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

557599:MKAN RS21725
gene id: 557599:MKAN_RS21725
uniprot id: U5WU95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

557599:MKAN RS02085
gene id: 557599:MKAN_RS02085
uniprot id: U5WJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

557599:MKAN RS11855
gene id: 557599:MKAN_RS11855
uniprot id: U5WSD2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

557599:MKAN RS23130
gene id: 557599:MKAN_RS23130
uniprot id: U5WV32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

557599:MKAN RS01350
gene id: 557599:MKAN_RS01350
uniprot id: U5WJ06
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

557599:MKAN RS23265
gene id: 557599:MKAN_RS23265
uniprot id: U5WYI9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS11190
gene id: 557599:MKAN_RS11190
uniprot id: U5WS15
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS22065
gene id: 557599:MKAN_RS22065
uniprot id: U5WXU0
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS18885
gene id: 557599:MKAN_RS18885
uniprot id: U5WTM0
names: Similarity
messages: Belongs to the peptidase S49 family.

557599:MKAN RS19825
gene id: 557599:MKAN_RS19825
uniprot id: U5WT96
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

557599:MKAN RS26840
gene id: 557599:MKAN_RS26840
uniprot id: U5WX82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

557599:MKAN RS19910
gene id: 557599:MKAN_RS19910
uniprot id: U5WU59
names: Similarity
messages: Belongs to the peptidase M20A family.

557599:MKAN RS21770
gene id: 557599:MKAN_RS21770
uniprot id: U5WUI9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS25285
gene id: 557599:MKAN_RS25285
uniprot id: U5WZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

557599:MKAN RS08195
gene id: 557599:MKAN_RS08195
uniprot id: U5WMD0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

557599:MKAN RS04530
gene id: 557599:MKAN_RS04530
uniprot id: U5WNQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

557599:MKAN RS21385
gene id: 557599:MKAN_RS21385
uniprot id: U5WUD0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS12695
gene id: 557599:MKAN_RS12695
uniprot id: U5WPK1
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

557599:MKAN RS26920
gene id: 557599:MKAN_RS26920
uniprot id: U5WXT4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

557599:MKAN RS13645
gene id: 557599:MKAN_RS13645
uniprot id: U5WQ09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

557599:MKAN RS25250
gene id: 557599:MKAN_RS25250
uniprot id: U5WWC9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS11815
gene id: 557599:MKAN_RS11815
uniprot id: U5WPV1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

557599:MKAN RS10515
gene id: 557599:MKAN_RS10515
uniprot id: U5X1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

557599:MKAN RS10405
gene id: 557599:MKAN_RS10405
uniprot id: U5WS54
names: Similarity
messages: Belongs to the stealth family.

557599:MKAN RS02630
gene id: 557599:MKAN_RS02630
uniprot id: U5WMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

557599:MKAN RS21165
gene id: 557599:MKAN_RS21165
uniprot id: U5WXR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS00480
gene id: 557599:MKAN_RS00480
uniprot id: U5WIG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

557599:MKAN RS00220
gene id: 557599:MKAN_RS00220
uniprot id: U5WIU0
names: Similarity
messages: Belongs to the EccE family.

557599:MKAN RS23230
gene id: 557599:MKAN_RS23230
uniprot id: U5WV53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

557599:MKAN RS23175
gene id: 557599:MKAN_RS23175
uniprot id: U5WVW2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS19015
gene id: 557599:MKAN_RS19015
uniprot id: U5WSV2
names: Similarity
messages: Belongs to the HIBADH-related family.

557599:MKAN RS10565
gene id: 557599:MKAN_RS10565
uniprot id: U5WP89
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

557599:MKAN RS05385
gene id: 557599:MKAN_RS05385
uniprot id: U5WPH2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS23090
gene id: 557599:MKAN_RS23090
uniprot id: U5WYF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

557599:MKAN RS03365
gene id: 557599:MKAN_RS03365
uniprot id: U5WN33
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS22970
gene id: 557599:MKAN_RS22970
uniprot id: U5WV55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

557599:MKAN RS17465
gene id: 557599:MKAN_RS17465
uniprot id: U5WVR0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

557599:MKAN RS22025
gene id: 557599:MKAN_RS22025
uniprot id: U5WV83
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

557599:MKAN RS24115
gene id: 557599:MKAN_RS24115
uniprot id: U5WZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

557599:MKAN RS17455
gene id: 557599:MKAN_RS17455
uniprot id: U5WS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

557599:MKAN RS04160
gene id: 557599:MKAN_RS04160
uniprot id: U5WK97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

557599:MKAN RS21360
gene id: 557599:MKAN_RS21360
uniprot id: U5WUC5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS09500
gene id: 557599:MKAN_RS09500
uniprot id: U5WN06
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS04350
gene id: 557599:MKAN_RS04350
uniprot id: U5WP14
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

557599:MKAN RS24565
gene id: 557599:MKAN_RS24565
uniprot id: U5WVQ7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

557599:MKAN RS23150
gene id: 557599:MKAN_RS23150
uniprot id: U5WVW0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

557599:MKAN RS14060
gene id: 557599:MKAN_RS14060
uniprot id: U5WQ79
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

557599:MKAN RS23615
gene id: 557599:MKAN_RS23615
uniprot id: U5WVJ2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

557599:MKAN RS27695
gene id: 557599:MKAN_RS27695
uniprot id: U5WXM5
names: Similarity
messages: Belongs to the UPF0145 family.

557599:MKAN RS16085
gene id: 557599:MKAN_RS16085
uniprot id: U5WS60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS25870
gene id: 557599:MKAN_RS25870
uniprot id: U5WWI3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

557599:MKAN RS05775
gene id: 557599:MKAN_RS05775
uniprot id: U5WL49
names: Similarity
messages: Belongs to the AccD/PCCB family.

557599:MKAN RS00425
gene id: 557599:MKAN_RS00425
uniprot id: U5WIF5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

557599:MKAN RS25935
gene id: 557599:MKAN_RS25935
uniprot id: U5X0B0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS07640
gene id: 557599:MKAN_RS07640
uniprot id: U5WLZ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

557599:MKAN RS04050
gene id: 557599:MKAN_RS04050
uniprot id: U5WNX3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

557599:MKAN RS27155
gene id: 557599:MKAN_RS27155
uniprot id: U5WXC5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

557599:MKAN RS21150
gene id: 557599:MKAN_RS21150
uniprot id: U5WU02
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS11145
gene id: 557599:MKAN_RS11145
uniprot id: U5WNN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS25230
gene id: 557599:MKAN_RS25230
uniprot id: U5WZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

557599:MKAN RS12880
gene id: 557599:MKAN_RS12880
uniprot id: U5WPT9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS14085
gene id: 557599:MKAN_RS14085
uniprot id: U5WQ83
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS02865
gene id: 557599:MKAN_RS02865
uniprot id: U5WMU9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

557599:MKAN RS04070
gene id: 557599:MKAN_RS04070
uniprot id: U5WNJ7
names: Similarity
messages: Belongs to the peptidase A31 family.

557599:MKAN RS21740
gene id: 557599:MKAN_RS21740
uniprot id: U5WXP4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS00215
gene id: 557599:MKAN_RS00215
uniprot id: U5WLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS18715
gene id: 557599:MKAN_RS18715
uniprot id: U5WW33
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

557599:MKAN RS00070
gene id: 557599:MKAN_RS00070
uniprot id: U5WIR5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

557599:MKAN RS21460
gene id: 557599:MKAN_RS21460
uniprot id: U5WUE1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS23815
gene id: 557599:MKAN_RS23815
uniprot id: U5WVE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

557599:MKAN RS13335
gene id: 557599:MKAN_RS13335
uniprot id: U5WPV4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS28140
gene id: 557599:MKAN_RS28140
uniprot id: U5X0C5
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS22605
gene id: 557599:MKAN_RS22605
uniprot id: U5WVI9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS10920
gene id: 557599:MKAN_RS10920
uniprot id: U5WPD4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

557599:MKAN RS20390
gene id: 557599:MKAN_RS20390
uniprot id: U5WTX6
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS15605
gene id: 557599:MKAN_RS15605
uniprot id: U5WR45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS22105
gene id: 557599:MKAN_RS22105
uniprot id: U5WUE6
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

557599:MKAN RS23355
gene id: 557599:MKAN_RS23355
uniprot id: U5WVZ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS08495
gene id: 557599:MKAN_RS08495
uniprot id: U5WMC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS18405
gene id: 557599:MKAN_RS18405
uniprot id: U5WSR8
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

557599:MKAN RS18495
gene id: 557599:MKAN_RS18495
uniprot id: U5WSK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

557599:MKAN RS00460
gene id: 557599:MKAN_RS00460
uniprot id: U5WLL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

557599:MKAN RS06930
gene id: 557599:MKAN_RS06930
uniprot id: U5WLN2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS10230
gene id: 557599:MKAN_RS10230
uniprot id: U5WS33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

557599:MKAN RS08105
gene id: 557599:MKAN_RS08105
uniprot id: U5WMY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS07535
gene id: 557599:MKAN_RS07535
uniprot id: U5WM35
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

557599:MKAN RS09160
gene id: 557599:MKAN_RS09160
uniprot id: U5WMQ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS00340
gene id: 557599:MKAN_RS00340
uniprot id: U5WI95
names: Similarity
messages: Belongs to the UPF0749 family.

557599:MKAN RS14255
gene id: 557599:MKAN_RS14255
uniprot id: U5WTM4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS13735
gene id: 557599:MKAN_RS13735
uniprot id: U5WTT5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

557599:MKAN RS02785
gene id: 557599:MKAN_RS02785
uniprot id: U5WJL6
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

557599:MKAN RS21200
gene id: 557599:MKAN_RS21200
uniprot id: U5WU10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS08115
gene id: 557599:MKAN_RS08115
uniprot id: U5WMB5
names: Similarity
messages: Belongs to the ArsC family.

557599:MKAN RS15105
gene id: 557599:MKAN_RS15105
uniprot id: U5WU72
names: Similarity
messages: Belongs to the peptidase S1C family.

557599:MKAN RS21090
gene id: 557599:MKAN_RS21090
uniprot id: U5WUT4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS24910
gene id: 557599:MKAN_RS24910
uniprot id: U5WWR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

557599:MKAN RS19835
gene id: 557599:MKAN_RS19835
uniprot id: U5WWN3
names: Cofactor
messages: The heme is bound between the two transmembrane subunits.

557599:MKAN RS16840
gene id: 557599:MKAN_RS16840
uniprot id: U5WV15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

557599:MKAN RS14120
gene id: 557599:MKAN_RS14120
uniprot id: U5WTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

557599:MKAN RS26710
gene id: 557599:MKAN_RS26710
uniprot id: U5X0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

557599:MKAN RS05320
gene id: 557599:MKAN_RS05320
uniprot id: U5WP37
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: Membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

557599:MKAN RS06405
gene id: 557599:MKAN_RS06405
uniprot id: U5WLB3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS05880
gene id: 557599:MKAN_RS05880
uniprot id: U5WLQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

557599:MKAN RS23360
gene id: 557599:MKAN_RS23360
uniprot id: U5WV73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

557599:MKAN RS19895
gene id: 557599:MKAN_RS19895
uniprot id: U5WTJ1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

557599:MKAN RS27105
gene id: 557599:MKAN_RS27105
uniprot id: U5WXC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

557599:MKAN RS08670
gene id: 557599:MKAN_RS08670
uniprot id: U5WR79
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS21480
gene id: 557599:MKAN_RS21480
uniprot id: U5WU55
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

557599:MKAN RS23555
gene id: 557599:MKAN_RS23555
uniprot id: U5WW27
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS02945
gene id: 557599:MKAN_RS02945
uniprot id: U5WN84
names: Similarity
messages: Belongs to the TPP enzyme family.

557599:MKAN RS22430
gene id: 557599:MKAN_RS22430
uniprot id: U5WUW1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

557599:MKAN RS17215
gene id: 557599:MKAN_RS17215
uniprot id: U5WVL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

557599:MKAN RS19700
gene id: 557599:MKAN_RS19700
uniprot id: U5WU22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS26855
gene id: 557599:MKAN_RS26855
uniprot id: U5WXS7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

557599:MKAN RS14150
gene id: 557599:MKAN_RS14150
uniprot id: U5WU04
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

557599:MKAN RS20805
gene id: 557599:MKAN_RS20805
uniprot id: U5WUP1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

557599:MKAN RS00315
gene id: 557599:MKAN_RS00315
uniprot id: U5WI90
names: Similarity
messages: Belongs to the TPP enzyme family.

557599:MKAN RS19630
gene id: 557599:MKAN_RS19630
uniprot id: U5WT59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

557599:MKAN RS07580
gene id: 557599:MKAN_RS07580
uniprot id: U5WMP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

557599:MKAN RS04470
gene id: 557599:MKAN_RS04470
uniprot id: U5WKJ1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

557599:MKAN RS07320
gene id: 557599:MKAN_RS07320
uniprot id: U5WQ57
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

557599:MKAN RS27070
gene id: 557599:MKAN_RS27070
uniprot id: U5WXV9
names: Similarity
messages: Belongs to the TlyA family.

557599:MKAN RS19470
gene id: 557599:MKAN_RS19470
uniprot id: U5WWT9
names: Similarity
messages: Belongs to the TPP enzyme family.

557599:MKAN RS17820
gene id: 557599:MKAN_RS17820
uniprot id: U5WW16
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS11410
gene id: 557599:MKAN_RS11410
uniprot id: U5WNS7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS10640
gene id: 557599:MKAN_RS10640
uniprot id: U5WNM0
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS07745
gene id: 557599:MKAN_RS07745
uniprot id: U5WM09
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

557599:MKAN RS24790
gene id: 557599:MKAN_RS24790
uniprot id: U5WZ75
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS21035
gene id: 557599:MKAN_RS21035
uniprot id: U5WXP5
names: Similarity
messages: Belongs to the citrate synthase family.

557599:MKAN RS18360
gene id: 557599:MKAN_RS18360
uniprot id: U5WVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

557599:MKAN RS28915
gene id: 557599:MKAN_RS28915
uniprot id: U5WXS8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS10040
gene id: 557599:MKAN_RS10040
uniprot id: U5WNE3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS14385
gene id: 557599:MKAN_RS14385
uniprot id: U5WU41
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS12585
gene id: 557599:MKAN_RS12585
uniprot id: U5WTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

557599:MKAN RS18790
gene id: 557599:MKAN_RS18790
uniprot id: U5WSY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

557599:MKAN RS26820
gene id: 557599:MKAN_RS26820
uniprot id: U5X086
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

557599:MKAN RS11435
gene id: 557599:MKAN_RS11435
uniprot id: U5WPN1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS13820
gene id: 557599:MKAN_RS13820
uniprot id: U5WQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

557599:MKAN RS04450
gene id: 557599:MKAN_RS04450
uniprot id: U5WNP5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

557599:MKAN RS20255
gene id: 557599:MKAN_RS20255
uniprot id: U5WUE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS10045
gene id: 557599:MKAN_RS10045
uniprot id: U5WRJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS08470
gene id: 557599:MKAN_RS08470
uniprot id: U5WMB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

557599:MKAN RS19430
gene id: 557599:MKAN_RS19430
uniprot id: U5WT22
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS18780
gene id: 557599:MKAN_RS18780
uniprot id: U5WTK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

557599:MKAN RS19140
gene id: 557599:MKAN_RS19140
uniprot id: U5WWN0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS18755
gene id: 557599:MKAN_RS18755
uniprot id: U5WTJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

557599:MKAN RS09830
gene id: 557599:MKAN_RS09830
uniprot id: U5WRG6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS04085
gene id: 557599:MKAN_RS04085
uniprot id: U5WK88
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

557599:MKAN RS24330
gene id: 557599:MKAN_RS24330
uniprot id: U5WVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS21890
gene id: 557599:MKAN_RS21890
uniprot id: U5WY28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS18510
gene id: 557599:MKAN_RS18510
uniprot id: U5WWC7
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS01605
gene id: 557599:MKAN_RS01605
uniprot id: U5WJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

557599:MKAN RS17030
gene id: 557599:MKAN_RS17030
uniprot id: U5WSL9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

557599:MKAN RS12395
gene id: 557599:MKAN_RS12395
uniprot id: U5WSS4
names: Similarity
messages: Belongs to the type IB topoisomerase family.

557599:MKAN RS08645
gene id: 557599:MKAN_RS08645
uniprot id: U5WR74
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

557599:MKAN RS08765
gene id: 557599:MKAN_RS08765
uniprot id: U5WMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

557599:MKAN RS07335
gene id: 557599:MKAN_RS07335
uniprot id: U5WLU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS00415
gene id: 557599:MKAN_RS00415
uniprot id: U5WIX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

557599:MKAN RS14595
gene id: 557599:MKAN_RS14595
uniprot id: U5WQI3
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

557599:MKAN RS22080
gene id: 557599:MKAN_RS22080
uniprot id: U5WUE2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS13245
gene id: 557599:MKAN_RS13245
uniprot id: U5WTL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS24900
gene id: 557599:MKAN_RS24900
uniprot id: U5WZ92
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS24800
gene id: 557599:MKAN_RS24800
uniprot id: U5WZN4
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS02090
gene id: 557599:MKAN_RS02090
uniprot id: U5WJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

557599:MKAN RS08130
gene id: 557599:MKAN_RS08130
uniprot id: U5WMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

557599:MKAN RS21355
gene id: 557599:MKAN_RS21355
uniprot id: U5WU33
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS03175
gene id: 557599:MKAN_RS03175
uniprot id: U5WJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

557599:MKAN RS02165
gene id: 557599:MKAN_RS02165
uniprot id: U5WJU0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

557599:MKAN RS06065
gene id: 557599:MKAN_RS06065
uniprot id: U5WPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

557599:MKAN RS07160
gene id: 557599:MKAN_RS07160
uniprot id: U5WMH7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS24110
gene id: 557599:MKAN_RS24110
uniprot id: U5WYW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS07350
gene id: 557599:MKAN_RS07350
uniprot id: U5WM06
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS16800
gene id: 557599:MKAN_RS16800
uniprot id: U5WSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS11520
gene id: 557599:MKAN_RS11520
uniprot id: U5WP20
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

557599:MKAN RS24250
gene id: 557599:MKAN_RS24250
uniprot id: U5WVL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

557599:MKAN RS28130
gene id: 557599:MKAN_RS28130
uniprot id: U5X2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

557599:MKAN RS04195
gene id: 557599:MKAN_RS04195
uniprot id: U5WNL7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS05460
gene id: 557599:MKAN_RS05460
uniprot id: U5WYQ1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS26680
gene id: 557599:MKAN_RS26680
uniprot id: U5X066
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

557599:MKAN RS11670
gene id: 557599:MKAN_RS11670
uniprot id: U5WSQ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

557599:MKAN RS22995
gene id: 557599:MKAN_RS22995
uniprot id: U5WV61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

557599:MKAN RS23195
gene id: 557599:MKAN_RS23195
uniprot id: U5WYX1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

557599:MKAN RS25385
gene id: 557599:MKAN_RS25385
uniprot id: U5WWF1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

557599:MKAN RS09155
gene id: 557599:MKAN_RS09155
uniprot id: U5WNG6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

557599:MKAN RS04010
gene id: 557599:MKAN_RS04010
uniprot id: U5WK79
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS02605
gene id: 557599:MKAN_RS02605
uniprot id: U5WMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

557599:MKAN RS04650
gene id: 557599:MKAN_RS04650
uniprot id: U5WKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

557599:MKAN RS19365
gene id: 557599:MKAN_RS19365
uniprot id: U5WWE9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

557599:MKAN RS14125
gene id: 557599:MKAN_RS14125
uniprot id: U5WU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

557599:MKAN RS18610
gene id: 557599:MKAN_RS18610
uniprot id: U5WW13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS25245
gene id: 557599:MKAN_RS25245
uniprot id: U5WW24
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

557599:MKAN RS24655
gene id: 557599:MKAN_RS24655
uniprot id: U5WZL0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

557599:MKAN RS18195
gene id: 557599:MKAN_RS18195
uniprot id: U5WW78
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

557599:MKAN RS16950
gene id: 557599:MKAN_RS16950
uniprot id: U5WRR0
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS21170
gene id: 557599:MKAN_RS21170
uniprot id: U5WUU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS25200
gene id: 557599:MKAN_RS25200
uniprot id: U5WWC1
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

557599:MKAN RS03840
gene id: 557599:MKAN_RS03840
uniprot id: U5WNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

557599:MKAN RS20425
gene id: 557599:MKAN_RS20425
uniprot id: U5WX33
names: Similarity
messages: Belongs to the barstar family.

557599:MKAN RS24935
gene id: 557599:MKAN_RS24935
uniprot id: U5WWR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

557599:MKAN RS09405
gene id: 557599:MKAN_RS09405
uniprot id: U5WN46
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

557599:MKAN RS10570
gene id: 557599:MKAN_RS10570
uniprot id: U5WNF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

557599:MKAN RS20545
gene id: 557599:MKAN_RS20545
uniprot id: U5WUJ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS09535
gene id: 557599:MKAN_RS09535
uniprot id: U5WRC3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS12175
gene id: 557599:MKAN_RS12175
uniprot id: U5WPA1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS03020
gene id: 557599:MKAN_RS03020
uniprot id: U5WN99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

557599:MKAN RS00540
gene id: 557599:MKAN_RS00540
uniprot id: U5WLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

557599:MKAN RS14895
gene id: 557599:MKAN_RS14895
uniprot id: U5WU11
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS01200
gene id: 557599:MKAN_RS01200
uniprot id: U5WMF5
names: Similarity
messages: Belongs to the UPF0235 family.

557599:MKAN RS26785
gene id: 557599:MKAN_RS26785
uniprot id: U5WX75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

557599:MKAN RS24315
gene id: 557599:MKAN_RS24315
uniprot id: U5WZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS05325
gene id: 557599:MKAN_RS05325
uniprot id: U5WPG3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

557599:MKAN RS04045
gene id: 557599:MKAN_RS04045
uniprot id: U5WNJ2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

557599:MKAN RS26895
gene id: 557599:MKAN_RS26895
uniprot id: U5WX87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

557599:MKAN RS20565
gene id: 557599:MKAN_RS20565
uniprot id: U5WXH5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

557599:MKAN RS02870
gene id: 557599:MKAN_RS02870
uniprot id: U5WN67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

557599:MKAN RS00625
gene id: 557599:MKAN_RS00625
uniprot id: U5WJ14
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS08740
gene id: 557599:MKAN_RS08740
uniprot id: U5WMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

557599:MKAN RS13850
gene id: 557599:MKAN_RS13850
uniprot id: U5WQ43
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS22485
gene id: 557599:MKAN_RS22485
uniprot id: U5WY11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS09415
gene id: 557599:MKAN_RS09415
uniprot id: U5WRQ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS13580
gene id: 557599:MKAN_RS13580
uniprot id: U5WTA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

557599:MKAN RS11645
gene id: 557599:MKAN_RS11645
uniprot id: U5WSQ2
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS12875
gene id: 557599:MKAN_RS12875
uniprot id: U5WPN2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS06515
gene id: 557599:MKAN_RS06515
uniprot id: U5WQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

557599:MKAN RS01400
gene id: 557599:MKAN_RS01400
uniprot id: U5WIX5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS27485
gene id: 557599:MKAN_RS27485
uniprot id: U5WXI2
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS12115
gene id: 557599:MKAN_RS12115
uniprot id: U5WQ15
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS14635
gene id: 557599:MKAN_RS14635
uniprot id: U5WRA6
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

557599:MKAN RS00200
gene id: 557599:MKAN_RS00200
uniprot id: U5WP40
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS02285
gene id: 557599:MKAN_RS02285
uniprot id: U5WMX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS08795
gene id: 557599:MKAN_RS08795
uniprot id: U5WMI2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

557599:MKAN RS03635
gene id: 557599:MKAN_RS03635
uniprot id: U5X0X5
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS20040
gene id: 557599:MKAN_RS20040
uniprot id: U5WTD5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

557599:MKAN RS13825
gene id: 557599:MKAN_RS13825
uniprot id: U5WQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

557599:MKAN RS18395
gene id: 557599:MKAN_RS18395
uniprot id: U5WTD9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

557599:MKAN RS00225
gene id: 557599:MKAN_RS00225
uniprot id: U5WI75
names: Subcellular Location Annotation
messages: Cytoplasm

557599:MKAN RS14845
gene id: 557599:MKAN_RS14845
uniprot id: U5WQN3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS00650
gene id: 557599:MKAN_RS00650
uniprot id: C5MTG2
names: Subcellular Location Annotation
messages: Cytoplasm

557599:MKAN RS26635
gene id: 557599:MKAN_RS26635
uniprot id: U5X0M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

557599:MKAN RS15720
gene id: 557599:MKAN_RS15720
uniprot id: U5WRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

557599:MKAN RS22250
gene id: 557599:MKAN_RS22250
uniprot id: U5WY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

557599:MKAN RS25970
gene id: 557599:MKAN_RS25970
uniprot id: U5WWK1
names: Similarity
messages: Belongs to the peptidase C40 family.

557599:MKAN RS18865
gene id: 557599:MKAN_RS18865
uniprot id: U5WSZ2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

557599:MKAN RS06110
gene id: 557599:MKAN_RS06110
uniprot id: U5WLB1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

557599:MKAN RS03015
gene id: 557599:MKAN_RS03015
uniprot id: U5WMX5
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS22580
gene id: 557599:MKAN_RS22580
uniprot id: U5WVI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

557599:MKAN RS16185
gene id: 557599:MKAN_RS16185
uniprot id: U5WV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

557599:MKAN RS03410
gene id: 557599:MKAN_RS03410
uniprot id: U5WJW3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS14650
gene id: 557599:MKAN_RS14650
uniprot id: U5WTU1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

557599:MKAN RS15370
gene id: 557599:MKAN_RS15370
uniprot id: U5WUP7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

557599:MKAN RS13180
gene id: 557599:MKAN_RS13180
uniprot id: U5WPT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

557599:MKAN RS11140
gene id: 557599:MKAN_RS11140
uniprot id: U5WPH4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS03210
gene id: 557599:MKAN_RS03210
uniprot id: U5WN05
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

557599:MKAN RS10995
gene id: 557599:MKAN_RS10995
uniprot id: U5WPE9
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS21350
gene id: 557599:MKAN_RS21350
uniprot id: U5WUY0
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

557599:MKAN RS26540
gene id: 557599:MKAN_RS26540
uniprot id: U5X048
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

557599:MKAN RS07970
gene id: 557599:MKAN_RS07970
uniprot id: U5WMW0
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS21120
gene id: 557599:MKAN_RS21120
uniprot id: U5WTZ9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS01070
gene id: 557599:MKAN_RS01070
uniprot id: U5WJB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

557599:MKAN RS26760
gene id: 557599:MKAN_RS26760
uniprot id: U5X076
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

557599:MKAN RS02990
gene id: 557599:MKAN_RS02990
uniprot id: U5WMX1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

557599:MKAN RS06020
gene id: 557599:MKAN_RS06020
uniprot id: U5WL95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

557599:MKAN RS23925
gene id: 557599:MKAN_RS23925
uniprot id: U5WVP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS18775
gene id: 557599:MKAN_RS18775
uniprot id: U5WWG6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

557599:MKAN RS10925
gene id: 557599:MKAN_RS10925
uniprot id: U5WNJ8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

557599:MKAN RS23695
gene id: 557599:MKAN_RS23695
uniprot id: U5WVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

557599:MKAN RS09520
gene id: 557599:MKAN_RS09520
uniprot id: U5WNS5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

557599:MKAN RS07005
gene id: 557599:MKAN_RS07005
uniprot id: U5WLP4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS18155
gene id: 557599:MKAN_RS18155
uniprot id: U5WSF9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

557599:MKAN RS13395
gene id: 557599:MKAN_RS13395
uniprot id: U5WPW4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

557599:MKAN RS09875
gene id: 557599:MKAN_RS09875
uniprot id: U5WRY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS13895
gene id: 557599:MKAN_RS13895
uniprot id: U5WQX7
names: Similarity
messages: Belongs to the EccE family.

557599:MKAN RS25605
gene id: 557599:MKAN_RS25605
uniprot id: U5WX41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

557599:MKAN RS08975
gene id: 557599:MKAN_RS08975
uniprot id: U5WMT2
names: Similarity
messages: Belongs to the citrate synthase family.

557599:MKAN RS13730
gene id: 557599:MKAN_RS13730
uniprot id: U5WTD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

557599:MKAN RS05430
gene id: 557599:MKAN_RS05430
uniprot id: U5WP56
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS19730
gene id: 557599:MKAN_RS19730
uniprot id: U5WT79
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

557599:MKAN RS00680
gene id: 557599:MKAN_RS00680
uniprot id: U5WJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

557599:MKAN RS18335
gene id: 557599:MKAN_RS18335
uniprot id: U5WYW8
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS06060
gene id: 557599:MKAN_RS06060
uniprot id: U5WLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

557599:MKAN RS06555
gene id: 557599:MKAN_RS06555
uniprot id: U5WM29
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS14425
gene id: 557599:MKAN_RS14425
uniprot id: U5WQK6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

557599:MKAN RS22560
gene id: 557599:MKAN_RS22560
uniprot id: U5WUN7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

557599:MKAN RS17605
gene id: 557599:MKAN_RS17605
uniprot id: U5WSD0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

557599:MKAN RS23975
gene id: 557599:MKAN_RS23975
uniprot id: U5WVH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

557599:MKAN RS06830
gene id: 557599:MKAN_RS06830
uniprot id: U5WLL5
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

557599:MKAN RS08800
gene id: 557599:MKAN_RS08800
uniprot id: U5WMQ1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS15035
gene id: 557599:MKAN_RS15035
uniprot id: U5WUI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS23390
gene id: 557599:MKAN_RS23390
uniprot id: U5WVF8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS22740
gene id: 557599:MKAN_RS22740
uniprot id: U5WVL8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

557599:MKAN RS26950
gene id: 557599:MKAN_RS26950
uniprot id: U5WWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

557599:MKAN RS24815
gene id: 557599:MKAN_RS24815
uniprot id: U5WW42
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

557599:MKAN RS07675
gene id: 557599:MKAN_RS07675
uniprot id: U5WM56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS09570
gene id: 557599:MKAN_RS09570
uniprot id: U5WNT4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS12350
gene id: 557599:MKAN_RS12350
uniprot id: U5WPF4
names: Similarity
messages: Belongs to the NodU/CmcH family.

557599:MKAN RS00710
gene id: 557599:MKAN_RS00710
uniprot id: U5WJ28
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS17980
gene id: 557599:MKAN_RS17980
uniprot id: U5WT67
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

557599:MKAN RS24285
gene id: 557599:MKAN_RS24285
uniprot id: U5WYZ7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

557599:MKAN RS02505
gene id: 557599:MKAN_RS02505
uniprot id: U5WK06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS18770
gene id: 557599:MKAN_RS18770
uniprot id: U5WW44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

557599:MKAN RS06780
gene id: 557599:MKAN_RS06780
uniprot id: U5WPW5
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS27225
gene id: 557599:MKAN_RS27225
uniprot id: U5WX37
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

557599:MKAN RS27805
gene id: 557599:MKAN_RS27805
uniprot id: U5X323
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

557599:MKAN RS06120
gene id: 557599:MKAN_RS06120
uniprot id: U5WPV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

557599:MKAN RS23945
gene id: 557599:MKAN_RS23945
uniprot id: U5WVG5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

557599:MKAN RS17195
gene id: 557599:MKAN_RS17195
uniprot id: U5WSP9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS11370
gene id: 557599:MKAN_RS11370
uniprot id: U5WS48
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS14050
gene id: 557599:MKAN_RS14050
uniprot id: U5WTY8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

557599:MKAN RS26615
gene id: 557599:MKAN_RS26615
uniprot id: U5WWU3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS19085
gene id: 557599:MKAN_RS19085
uniprot id: U5WWM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

557599:MKAN RS20180
gene id: 557599:MKAN_RS20180
uniprot id: U5WUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

557599:MKAN RS18080
gene id: 557599:MKAN_RS18080
uniprot id: U5WSE8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS02410
gene id: 557599:MKAN_RS02410
uniprot id: U5WJB6
names: Similarity
messages: Belongs to the creatininase superfamily.

557599:MKAN RS13745
gene id: 557599:MKAN_RS13745
uniprot id: U5WQ28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

557599:MKAN RS04825
gene id: 557599:MKAN_RS04825
uniprot id: U5WKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

557599:MKAN RS03315
gene id: 557599:MKAN_RS03315
uniprot id: U5WN24
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS02780
gene id: 557599:MKAN_RS02780
uniprot id: U5WJI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS07705
gene id: 557599:MKAN_RS07705
uniprot id: U5WQB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS19090
gene id: 557599:MKAN_RS19090
uniprot id: U5WTQ9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

557599:MKAN RS06145
gene id: 557599:MKAN_RS06145
uniprot id: U5WPV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

557599:MKAN RS13165
gene id: 557599:MKAN_RS13165
uniprot id: U5WTK1
names: Similarity
messages: Belongs to the UPF0145 family.

557599:MKAN RS00865
gene id: 557599:MKAN_RS00865
uniprot id: U5WJ59
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

557599:MKAN RS05990
gene id: 557599:MKAN_RS05990
uniprot id: U5WL35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS12685
gene id: 557599:MKAN_RS12685
uniprot id: U5WTC6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.
messages: Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine.

557599:MKAN RS23870
gene id: 557599:MKAN_RS23870
uniprot id: U5WVN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS14830
gene id: 557599:MKAN_RS14830
uniprot id: U5WTY0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS00810
gene id: 557599:MKAN_RS00810
uniprot id: U5WJ48
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS25765
gene id: 557599:MKAN_RS25765
uniprot id: U5WWH0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

557599:MKAN RS17225
gene id: 557599:MKAN_RS17225
uniprot id: U5WSQ4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

557599:MKAN RS25610
gene id: 557599:MKAN_RS25610
uniprot id: U5WW95
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

557599:MKAN RS13355
gene id: 557599:MKAN_RS13355
uniprot id: U5X1M3
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS18645
gene id: 557599:MKAN_RS18645
uniprot id: U5WTI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

557599:MKAN RS19900
gene id: 557599:MKAN_RS19900
uniprot id: U5WWP0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

557599:MKAN RS03515
gene id: 557599:MKAN_RS03515
uniprot id: U5WJY5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

557599:MKAN RS05355
gene id: 557599:MKAN_RS05355
uniprot id: U5WP42
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS13030
gene id: 557599:MKAN_RS13030
uniprot id: U5WT15
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS26510
gene id: 557599:MKAN_RS26510
uniprot id: U5WX31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS24915
gene id: 557599:MKAN_RS24915
uniprot id: U5WVV9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

557599:MKAN RS23810
gene id: 557599:MKAN_RS23810
uniprot id: U5WW76
names: Similarity
messages: Belongs to the ribF family.

557599:MKAN RS04815
gene id: 557599:MKAN_RS04815
uniprot id: U5WL84
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

557599:MKAN RS05930
gene id: 557599:MKAN_RS05930
uniprot id: U5WPR3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

557599:MKAN RS25135
gene id: 557599:MKAN_RS25135
uniprot id: U5WZT9
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS17170
gene id: 557599:MKAN_RS17170
uniprot id: U5WYT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

557599:MKAN RS04375
gene id: 557599:MKAN_RS04375
uniprot id: U5WNN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

557599:MKAN RS22170
gene id: 557599:MKAN_RS22170
uniprot id: U5WY68
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS05330
gene id: 557599:MKAN_RS05330
uniprot id: U5WLG9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS25455
gene id: 557599:MKAN_RS25455
uniprot id: U5WW70
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS17475
gene id: 557599:MKAN_RS17475
uniprot id: U5WS14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

557599:MKAN RS27900
gene id: 557599:MKAN_RS27900
uniprot id: U5X335
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS04430
gene id: 557599:MKAN_RS04430
uniprot id: U5WP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

557599:MKAN RS16175
gene id: 557599:MKAN_RS16175
uniprot id: U5WRJ1
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS15170
gene id: 557599:MKAN_RS15170
uniprot id: U5WUL2
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

557599:MKAN RS17105
gene id: 557599:MKAN_RS17105
uniprot id: U5WSN3
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

557599:MKAN RS20740
gene id: 557599:MKAN_RS20740
uniprot id: U5WTU4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

557599:MKAN RS00405
gene id: 557599:MKAN_RS00405
uniprot id: U5WLK7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS08910
gene id: 557599:MKAN_RS08910
uniprot id: U5WRC0
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS05785
gene id: 557599:MKAN_RS05785
uniprot id: U5WPP0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS27465
gene id: 557599:MKAN_RS27465
uniprot id: U5X0J2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

557599:MKAN RS02820
gene id: 557599:MKAN_RS02820
uniprot id: U5WN57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

557599:MKAN RS15850
gene id: 557599:MKAN_RS15850
uniprot id: U5WS17
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS11935
gene id: 557599:MKAN_RS11935
uniprot id: U5WSE5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS11490
gene id: 557599:MKAN_RS11490
uniprot id: U5WNU3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS26705
gene id: 557599:MKAN_RS26705
uniprot id: U5X070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

557599:MKAN RS20635
gene id: 557599:MKAN_RS20635
uniprot id: U5WUK6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

557599:MKAN RS19315
gene id: 557599:MKAN_RS19315
uniprot id: U5WWQ9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS17645
gene id: 557599:MKAN_RS17645
uniprot id: U5WT13
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

557599:MKAN RS22300
gene id: 557599:MKAN_RS22300
uniprot id: U5WXX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

557599:MKAN RS27525
gene id: 557599:MKAN_RS27525
uniprot id: U5X106
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS16000
gene id: 557599:MKAN_RS16000
uniprot id: U5WRG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS16030
gene id: 557599:MKAN_RS16030
uniprot id: U5WV12
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

557599:MKAN RS04170
gene id: 557599:MKAN_RS04170
uniprot id: U5WNL3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

557599:MKAN RS23540
gene id: 557599:MKAN_RS23540
uniprot id: U5WVI0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

557599:MKAN RS12535
gene id: 557599:MKAN_RS12535
uniprot id: U5WPP1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS16230
gene id: 557599:MKAN_RS16230
uniprot id: U5WUR6
names: Similarity
messages: Belongs to the EccE family.

557599:MKAN RS04325
gene id: 557599:MKAN_RS04325
uniprot id: U5WKZ7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS21030
gene id: 557599:MKAN_RS21030
uniprot id: U5WXB4
names: Similarity
messages: Belongs to the PrpD family.

557599:MKAN RS01175
gene id: 557599:MKAN_RS01175
uniprot id: U5WMF1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS26665
gene id: 557599:MKAN_RS26665
uniprot id: U5WXP7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS11605
gene id: 557599:MKAN_RS11605
uniprot id: U5WNW4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS15090
gene id: 557599:MKAN_RS15090
uniprot id: U5WRN1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

557599:MKAN RS17310
gene id: 557599:MKAN_RS17310
uniprot id: U5WYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS23875
gene id: 557599:MKAN_RS23875
uniprot id: U5WYS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

557599:MKAN RS09205
gene id: 557599:MKAN_RS09205
uniprot id: U5WNH9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS09305
gene id: 557599:MKAN_RS09305
uniprot id: U5WRJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS20225
gene id: 557599:MKAN_RS20225
uniprot id: U5WX95
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

557599:MKAN RS18890
gene id: 557599:MKAN_RS18890
uniprot id: U5WSS5
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS25260
gene id: 557599:MKAN_RS25260
uniprot id: U5WZW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

557599:MKAN RS18025
gene id: 557599:MKAN_RS18025
uniprot id: U5WW53
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

557599:MKAN RS08725
gene id: 557599:MKAN_RS08725
uniprot id: U5WQU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

557599:MKAN RS17745
gene id: 557599:MKAN_RS17745
uniprot id: U5WSA1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS19125
gene id: 557599:MKAN_RS19125
uniprot id: U5WSX2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

557599:MKAN RS04965
gene id: 557599:MKAN_RS04965
uniprot id: U5WKR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

557599:MKAN RS22415
gene id: 557599:MKAN_RS22415
uniprot id: U5WYB2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

557599:MKAN RS18365
gene id: 557599:MKAN_RS18365
uniprot id: U5WWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS08580
gene id: 557599:MKAN_RS08580
uniprot id: U5WMK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

557599:MKAN RS19270
gene id: 557599:MKAN_RS19270
uniprot id: U5WTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

557599:MKAN RS28590
gene id: 557599:MKAN_RS28590
uniprot id: U5WJB0
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

557599:MKAN RS11355
gene id: 557599:MKAN_RS11355
uniprot id: U5WNR7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS07965
gene id: 557599:MKAN_RS07965
uniprot id: U5WQV2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS18570
gene id: 557599:MKAN_RS18570
uniprot id: U5WTG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

557599:MKAN RS27545
gene id: 557599:MKAN_RS27545
uniprot id: U5X0K6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

557599:MKAN RS05235
gene id: 557599:MKAN_RS05235
uniprot id: U5WP22
names: Similarity
messages: Belongs to the LacAB/RpiB family.

557599:MKAN RS17505
gene id: 557599:MKAN_RS17505
uniprot id: U5WS77
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

557599:MKAN RS23790
gene id: 557599:MKAN_RS23790
uniprot id: U5WVE1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

557599:MKAN RS20175
gene id: 557599:MKAN_RS20175
uniprot id: U5WX69
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS22200
gene id: 557599:MKAN_RS22200
uniprot id: U5WVB7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS13900
gene id: 557599:MKAN_RS13900
uniprot id: U5WQ51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

557599:MKAN RS04685
gene id: 557599:MKAN_RS04685
uniprot id: U5WNS6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS25040
gene id: 557599:MKAN_RS25040
uniprot id: U5WVY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS02885
gene id: 557599:MKAN_RS02885
uniprot id: U5WJN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

557599:MKAN RS02975
gene id: 557599:MKAN_RS02975
uniprot id: U5WK81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

557599:MKAN RS16200
gene id: 557599:MKAN_RS16200
uniprot id: U5WRJ5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS04335
gene id: 557599:MKAN_RS04335
uniprot id: U5WKH2
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS21205
gene id: 557599:MKAN_RS21205
uniprot id: U5WU97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS00510
gene id: 557599:MKAN_RS00510
uniprot id: U5WIH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

557599:MKAN RS06125
gene id: 557599:MKAN_RS06125
uniprot id: U5WLV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS13500
gene id: 557599:MKAN_RS13500
uniprot id: U5WQR2
names: Similarity
messages: Belongs to the AccD/PCCB family.

557599:MKAN RS21825
gene id: 557599:MKAN_RS21825
uniprot id: U5WV57
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS14740
gene id: 557599:MKAN_RS14740
uniprot id: U5WQL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

557599:MKAN RS26575
gene id: 557599:MKAN_RS26575
uniprot id: U5WXN3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

557599:MKAN RS12700
gene id: 557599:MKAN_RS12700
uniprot id: U5WPR5
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

557599:MKAN RS00760
gene id: 557599:MKAN_RS00760
uniprot id: U5WJ38
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS08200
gene id: 557599:MKAN_RS08200
uniprot id: U5WQK7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

557599:MKAN RS08600
gene id: 557599:MKAN_RS08600
uniprot id: U5WME4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

557599:MKAN RS17890
gene id: 557599:MKAN_RS17890
uniprot id: U5WSI9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

557599:MKAN RS17155
gene id: 557599:MKAN_RS17155
uniprot id: U5WSP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

557599:MKAN RS00940
gene id: 557599:MKAN_RS00940
uniprot id: U5WLW0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS18400
gene id: 557599:MKAN_RS18400
uniprot id: U5WSJ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

557599:MKAN RS28595
gene id: 557599:MKAN_RS28595
uniprot id: U5X195
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS04420
gene id: 557599:MKAN_RS04420
uniprot id: U5WKI3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS09650
gene id: 557599:MKAN_RS09650
uniprot id: U5WN27
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS09840
gene id: 557599:MKAN_RS09840
uniprot id: U5WNX9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

557599:MKAN RS20395
gene id: 557599:MKAN_RS20395
uniprot id: U5WYP0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS25355
gene id: 557599:MKAN_RS25355
uniprot id: U5WW45
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

557599:MKAN RS02215
gene id: 557599:MKAN_RS02215
uniprot id: U5WJU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

557599:MKAN RS19290
gene id: 557599:MKAN_RS19290
uniprot id: U5WWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

557599:MKAN RS12775
gene id: 557599:MKAN_RS12775
uniprot id: U5WPS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

557599:MKAN RS16500
gene id: 557599:MKAN_RS16500
uniprot id: U5WRN8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

557599:MKAN RS13455
gene id: 557599:MKAN_RS13455
uniprot id: U5WQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS14225
gene id: 557599:MKAN_RS14225
uniprot id: U5WTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

557599:MKAN RS22680
gene id: 557599:MKAN_RS22680
uniprot id: U5WYF8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

557599:MKAN RS13285
gene id: 557599:MKAN_RS13285
uniprot id: U5WT57
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS08085
gene id: 557599:MKAN_RS08085
uniprot id: U5WMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

557599:MKAN RS09605
gene id: 557599:MKAN_RS09605
uniprot id: U5WN82
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS20150
gene id: 557599:MKAN_RS20150
uniprot id: U5WX65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS21720
gene id: 557599:MKAN_RS21720
uniprot id: U5WV42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

557599:MKAN RS18760
gene id: 557599:MKAN_RS18760
uniprot id: U5WSQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

557599:MKAN RS03495
gene id: 557599:MKAN_RS03495
uniprot id: U5WK05
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS11735
gene id: 557599:MKAN_RS11735
uniprot id: U5WPT5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

557599:MKAN RS24535
gene id: 557599:MKAN_RS24535
uniprot id: U5WVY7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

557599:MKAN RS19685
gene id: 557599:MKAN_RS19685
uniprot id: U5WTF3
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

557599:MKAN RS11950
gene id: 557599:MKAN_RS11950
uniprot id: U5WP36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

557599:MKAN RS12150
gene id: 557599:MKAN_RS12150
uniprot id: U5WPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS24030
gene id: 557599:MKAN_RS24030
uniprot id: U5WVR9
names: Similarity
messages: Belongs to the PspA/IM30 family.

557599:MKAN RS26965
gene id: 557599:MKAN_RS26965
uniprot id: U5X0A8
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
messages: Homodimer.

557599:MKAN RS14310
gene id: 557599:MKAN_RS14310
uniprot id: U5WTN4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

557599:MKAN RS23725
gene id: 557599:MKAN_RS23725
uniprot id: U5WYQ0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS22480
gene id: 557599:MKAN_RS22480
uniprot id: U5WUX3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

557599:MKAN RS25265
gene id: 557599:MKAN_RS25265
uniprot id: U5WWX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

557599:MKAN RS24925
gene id: 557599:MKAN_RS24925
uniprot id: U5WZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

557599:MKAN RS25475
gene id: 557599:MKAN_RS25475
uniprot id: U5X004
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

557599:MKAN RS17940
gene id: 557599:MKAN_RS17940
uniprot id: U5WSJ7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS02375
gene id: 557599:MKAN_RS02375
uniprot id: U5WJB2
names: Similarity
messages: Belongs to the UPF0098 family.

557599:MKAN RS12885
gene id: 557599:MKAN_RS12885
uniprot id: U5WSZ7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS26095
gene id: 557599:MKAN_RS26095
uniprot id: U5X0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

557599:MKAN RS07360
gene id: 557599:MKAN_RS07360
uniprot id: U5WQL3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS11675
gene id: 557599:MKAN_RS11675
uniprot id: U5WPS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS22550
gene id: 557599:MKAN_RS22550
uniprot id: U5WYD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

557599:MKAN RS05120
gene id: 557599:MKAN_RS05120
uniprot id: U5WKT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

557599:MKAN RS13405
gene id: 557599:MKAN_RS13405
uniprot id: U5WT76
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS22315
gene id: 557599:MKAN_RS22315
uniprot id: U5WUI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

557599:MKAN RS03520
gene id: 557599:MKAN_RS03520
uniprot id: U5WK10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS24065
gene id: 557599:MKAN_RS24065
uniprot id: U5WZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

557599:MKAN RS05955
gene id: 557599:MKAN_RS05955
uniprot id: U5WPR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

557599:MKAN RS24320
gene id: 557599:MKAN_RS24320
uniprot id: U5WWG7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS21020
gene id: 557599:MKAN_RS21020
uniprot id: U5WTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS08030
gene id: 557599:MKAN_RS08030
uniprot id: U5WM51
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS05115
gene id: 557599:MKAN_RS05115
uniprot id: U5WKP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

557599:MKAN RS22035
gene id: 557599:MKAN_RS22035
uniprot id: U5WUN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS11025
gene id: 557599:MKAN_RS11025
uniprot id: U5WNL5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS17825
gene id: 557599:MKAN_RS17825
uniprot id: U5WT41
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS15915
gene id: 557599:MKAN_RS15915
uniprot id: U5WUZ4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

557599:MKAN RS00025
gene id: 557599:MKAN_RS00025
uniprot id: U5WI32
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS09115
gene id: 557599:MKAN_RS09115
uniprot id: U5WMV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

557599:MKAN RS22575
gene id: 557599:MKAN_RS22575
uniprot id: U5WYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

557599:MKAN RS22410
gene id: 557599:MKAN_RS22410
uniprot id: U5WXZ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

557599:MKAN RS07000
gene id: 557599:MKAN_RS07000
uniprot id: U5WME2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

557599:MKAN RS21660
gene id: 557599:MKAN_RS21660
uniprot id: U5WXZ7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

557599:MKAN RS11720
gene id: 557599:MKAN_RS11720
uniprot id: U5X208
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS19020
gene id: 557599:MKAN_RS19020
uniprot id: U5WT17
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS11810
gene id: 557599:MKAN_RS11810
uniprot id: U5WST1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS07750
gene id: 557599:MKAN_RS07750
uniprot id: U5WM66
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS01525
gene id: 557599:MKAN_RS01525
uniprot id: U5WJJ0
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS04510
gene id: 557599:MKAN_RS04510
uniprot id: U5WP40
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS06910
gene id: 557599:MKAN_RS06910
uniprot id: U5WLT9
names: Function
names: Similarity
messages: Belongs to the Stf0 sulfotransferase family.
messages: Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S).

557599:MKAN RS24340
gene id: 557599:MKAN_RS24340
uniprot id: U5WZH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

557599:MKAN RS06005
gene id: 557599:MKAN_RS06005
uniprot id: U5WPS8
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

557599:MKAN RS26800
gene id: 557599:MKAN_RS26800
uniprot id: U5WXR9
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS21220
gene id: 557599:MKAN_RS21220
uniprot id: U5WZL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

557599:MKAN RS03090
gene id: 557599:MKAN_RS03090
uniprot id: U5WJP9
names: Similarity
messages: Belongs to the serpin family.

557599:MKAN RS11150
gene id: 557599:MKAN_RS11150
uniprot id: U5WNU5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

557599:MKAN RS11945
gene id: 557599:MKAN_RS11945
uniprot id: U5WPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

557599:MKAN RS23010
gene id: 557599:MKAN_RS23010
uniprot id: U5WVU3
names: Similarity
messages: Belongs to the P(II) protein family.

557599:MKAN RS06815
gene id: 557599:MKAN_RS06815
uniprot id: U5WPX1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS25930
gene id: 557599:MKAN_RS25930
uniprot id: U5WZV4
names: Similarity
messages: Belongs to the thioredoxin family.

557599:MKAN RS18010
gene id: 557599:MKAN_RS18010
uniprot id: U5WSE1
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS03955
gene id: 557599:MKAN_RS03955
uniprot id: U5WK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
messages: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
messages: Monomer.

557599:MKAN RS04970
gene id: 557599:MKAN_RS04970
uniprot id: U5WNX1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

557599:MKAN RS18600
gene id: 557599:MKAN_RS18600
uniprot id: U5WSM5
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

557599:MKAN RS06285
gene id: 557599:MKAN_RS06285
uniprot id: U5WPJ1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

557599:MKAN RS07150
gene id: 557599:MKAN_RS07150
uniprot id: U5WQ34
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS06580
gene id: 557599:MKAN_RS06580
uniprot id: U5WM34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

557599:MKAN RS21155
gene id: 557599:MKAN_RS21155
uniprot id: U5WU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS18805
gene id: 557599:MKAN_RS18805
uniprot id: U5WTK8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

557599:MKAN RS20800
gene id: 557599:MKAN_RS20800
uniprot id: U5WXL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS07455
gene id: 557599:MKAN_RS07455
uniprot id: U5WQ76
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS25430
gene id: 557599:MKAN_RS25430
uniprot id: U5WW64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

557599:MKAN RS07950
gene id: 557599:MKAN_RS07950
uniprot id: U5WM89
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS18350
gene id: 557599:MKAN_RS18350
uniprot id: U5WSJ1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS17600
gene id: 557599:MKAN_RS17600
uniprot id: U5WS75
names: Similarity
messages: Belongs to the UPF0336 family.

557599:MKAN RS14460
gene id: 557599:MKAN_RS14460
uniprot id: U5WU56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

557599:MKAN RS24880
gene id: 557599:MKAN_RS24880
uniprot id: U5WZP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

557599:MKAN RS25785
gene id: 557599:MKAN_RS25785
uniprot id: U5WX98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

557599:MKAN RS05090
gene id: 557599:MKAN_RS05090
uniprot id: U5WKT0
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

557599:MKAN RS21710
gene id: 557599:MKAN_RS21710
uniprot id: U5WXN9
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

557599:MKAN RS21865
gene id: 557599:MKAN_RS21865
uniprot id: U5WV60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

557599:MKAN RS20285
gene id: 557599:MKAN_RS20285
uniprot id: U5WTM6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

557599:MKAN RS19355
gene id: 557599:MKAN_RS19355
uniprot id: U5WT10
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

557599:MKAN RS00470
gene id: 557599:MKAN_RS00470
uniprot id: U5WIY4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

557599:MKAN RS13495
gene id: 557599:MKAN_RS13495
uniprot id: U5WTQ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS04890
gene id: 557599:MKAN_RS04890
uniprot id: U5WNV6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

557599:MKAN RS10755
gene id: 557599:MKAN_RS10755
uniprot id: U5WPB3
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS26570
gene id: 557599:MKAN_RS26570
uniprot id: U5X0L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

557599:MKAN RS15115
gene id: 557599:MKAN_RS15115
uniprot id: U5WRN9
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

557599:MKAN RS13910
gene id: 557599:MKAN_RS13910
uniprot id: U5WTH2
names: Similarity
messages: Belongs to the EccE family.

557599:MKAN RS08480
gene id: 557599:MKAN_RS08480
uniprot id: U5WQQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS20315
gene id: 557599:MKAN_RS20315
uniprot id: U5WTV9
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

557599:MKAN RS02175
gene id: 557599:MKAN_RS02175
uniprot id: U5WJB3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

557599:MKAN RS05740
gene id: 557599:MKAN_RS05740
uniprot id: U5WPA4
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS09865
gene id: 557599:MKAN_RS09865
uniprot id: U5WNC0
names: Similarity
messages: Belongs to the peptidase S33 family.

557599:MKAN RS00395
gene id: 557599:MKAN_RS00395
uniprot id: U5WIA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

557599:MKAN RS23510
gene id: 557599:MKAN_RS23510
uniprot id: U5WW19
names: Similarity
messages: Belongs to the peptidase A31 family.

557599:MKAN RS11280
gene id: 557599:MKAN_RS11280
uniprot id: U5WNQ4
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

557599:MKAN RS26590
gene id: 557599:MKAN_RS26590
uniprot id: U5X053
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

557599:MKAN RS23985
gene id: 557599:MKAN_RS23985
uniprot id: U5WYU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

557599:MKAN RS18485
gene id: 557599:MKAN_RS18485
uniprot id: U5WWC3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

557599:MKAN RS00250
gene id: 557599:MKAN_RS00250
uniprot id: U5WIU4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS14215
gene id: 557599:MKAN_RS14215
uniprot id: U5WQA5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

557599:MKAN RS06950
gene id: 557599:MKAN_RS06950
uniprot id: U5WMD4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

557599:MKAN RS09235
gene id: 557599:MKAN_RS09235
uniprot id: U5WMS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

557599:MKAN RS03995
gene id: 557599:MKAN_RS03995
uniprot id: U5WNI4
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS17995
gene id: 557599:MKAN_RS17995
uniprot id: U5WVR5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

557599:MKAN RS20190
gene id: 557599:MKAN_RS20190
uniprot id: U5WTP3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS06045
gene id: 557599:MKAN_RS06045
uniprot id: U5WPT2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

557599:MKAN RS14305
gene id: 557599:MKAN_RS14305
uniprot id: U5WQH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS23930
gene id: 557599:MKAN_RS23930
uniprot id: U5WYT3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS21140
gene id: 557599:MKAN_RS21140
uniprot id: U5WXR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS07770
gene id: 557599:MKAN_RS07770
uniprot id: U5WM12
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS15295
gene id: 557599:MKAN_RS15295
uniprot id: U5WUN4
names: Similarity
messages: Belongs to the pirin family.

557599:MKAN RS09555
gene id: 557599:MKAN_RS09555
uniprot id: U5WN75
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS25120
gene id: 557599:MKAN_RS25120
uniprot id: U5WVZ6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS12035
gene id: 557599:MKAN_RS12035
uniprot id: U5WPC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

557599:MKAN RS23475
gene id: 557599:MKAN_RS23475
uniprot id: U5WYL9
names: Similarity
messages: Belongs to the HypD family.

557599:MKAN RS13425
gene id: 557599:MKAN_RS13425
uniprot id: U5WPW9
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

557599:MKAN RS02260
gene id: 557599:MKAN_RS02260
uniprot id: U5WMX0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

557599:MKAN RS20520
gene id: 557599:MKAN_RS20520
uniprot id: U5WUI8
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

557599:MKAN RS07115
gene id: 557599:MKAN_RS07115
uniprot id: U5WLR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS06240
gene id: 557599:MKAN_RS06240
uniprot id: U5WLX5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

557599:MKAN RS18650
gene id: 557599:MKAN_RS18650
uniprot id: U5WSN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

557599:MKAN RS09525
gene id: 557599:MKAN_RS09525
uniprot id: U5WN09
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

557599:MKAN RS03335
gene id: 557599:MKAN_RS03335
uniprot id: U5WJX3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS12790
gene id: 557599:MKAN_RS12790
uniprot id: U5WQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

557599:MKAN RS25240
gene id: 557599:MKAN_RS25240
uniprot id: U5WWX4
names: Similarity
messages: Belongs to the peptidase A24 family.

557599:MKAN RS03165
gene id: 557599:MKAN_RS03165
uniprot id: U5WNC5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

557599:MKAN RS14320
gene id: 557599:MKAN_RS14320
uniprot id: U5WR51
names: Similarity
messages: Belongs to the peptidase C40 family.

557599:MKAN RS09495
gene id: 557599:MKAN_RS09495
uniprot id: U5WNS2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS15565
gene id: 557599:MKAN_RS15565
uniprot id: U5WUT2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

557599:MKAN RS22570
gene id: 557599:MKAN_RS22570
uniprot id: U5WY26
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

557599:MKAN RS11475
gene id: 557599:MKAN_RS11475
uniprot id: U5WS65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS11485
gene id: 557599:MKAN_RS11485
uniprot id: U5WPP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS15245
gene id: 557599:MKAN_RS15245
uniprot id: U5WUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS24930
gene id: 557599:MKAN_RS24930
uniprot id: U5WZQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS11820
gene id: 557599:MKAN_RS11820
uniprot id: U5WP11
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

557599:MKAN RS18455
gene id: 557599:MKAN_RS18455
uniprot id: U5WTE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

557599:MKAN RS24980
gene id: 557599:MKAN_RS24980
uniprot id: U5WZR4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. Carboxylic acid reductase subfamily.
messages: Binds 1 phosphopantetheine covalently.
messages: Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain likely catalyzes substrate activation by formation of an initial acyl-AMP intermediate, the central region contains the phosphopantetheine attachment site, and the C-terminal domain catalyzes the reduction by NADPH of the intermediate thioester formed from the attack of the phosphopantetheine thiol at the carbonyl carbon of acyl-AMP.

557599:MKAN RS17315
gene id: 557599:MKAN_RS17315
uniprot id: U5WS44
names: Similarity
messages: Belongs to the MmpS family.

557599:MKAN RS04495
gene id: 557599:MKAN_RS04495
uniprot id: U5WKE6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

557599:MKAN RS02575
gene id: 557599:MKAN_RS02575
uniprot id: U5WJH1
names: Similarity
messages: Belongs to the YggT family.

557599:MKAN RS15735
gene id: 557599:MKAN_RS15735
uniprot id: U5WUW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS13615
gene id: 557599:MKAN_RS13615
uniprot id: U5WQS9
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

557599:MKAN RS24995
gene id: 557599:MKAN_RS24995
uniprot id: U5WW79
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS08370
gene id: 557599:MKAN_RS08370
uniprot id: U5WMA4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS06265
gene id: 557599:MKAN_RS06265
uniprot id: U5WPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS18950
gene id: 557599:MKAN_RS18950
uniprot id: U5WW77
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS18150
gene id: 557599:MKAN_RS18150
uniprot id: U5WT95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

557599:MKAN RS03240
gene id: 557599:MKAN_RS03240
uniprot id: U5WND9
names: Similarity
messages: Belongs to the AccD/PCCB family.

557599:MKAN RS03730
gene id: 557599:MKAN_RS03730
uniprot id: U5WKM1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

557599:MKAN RS25440
gene id: 557599:MKAN_RS25440
uniprot id: U5WZJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

557599:MKAN RS00230
gene id: 557599:MKAN_RS00230
uniprot id: U5WIB9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS16880
gene id: 557599:MKAN_RS16880
uniprot id: U5WSJ5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS15285
gene id: 557599:MKAN_RS15285
uniprot id: U5WR41
names: Similarity
messages: Belongs to the Dps family.

557599:MKAN RS14140
gene id: 557599:MKAN_RS14140
uniprot id: U5WQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

557599:MKAN RS16340
gene id: 557599:MKAN_RS16340
uniprot id: U5WV68
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

557599:MKAN RS07680
gene id: 557599:MKAN_RS07680
uniprot id: U5WQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

557599:MKAN RS19200
gene id: 557599:MKAN_RS19200
uniprot id: U5WSY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

557599:MKAN RS04740
gene id: 557599:MKAN_RS04740
uniprot id: U5WNT3
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

557599:MKAN RS28910
gene id: 557599:MKAN_RS28910
uniprot id: U5WXM2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

557599:MKAN RS19590
gene id: 557599:MKAN_RS19590
uniprot id: U5WWI8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

557599:MKAN RS06230
gene id: 557599:MKAN_RS06230
uniprot id: U5WPH9
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

557599:MKAN RS18115
gene id: 557599:MKAN_RS18115
uniprot id: U5WVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

557599:MKAN RS17930
gene id: 557599:MKAN_RS17930
uniprot id: U5WT58
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS04615
gene id: 557599:MKAN_RS04615
uniprot id: U5WL51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

557599:MKAN RS27840
gene id: 557599:MKAN_RS27840
uniprot id: U5X072
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

557599:MKAN RS28250
gene id: 557599:MKAN_RS28250
uniprot id: U5X396
names: Similarity
messages: Belongs to the RelE toxin family.

557599:MKAN RS25005
gene id: 557599:MKAN_RS25005
uniprot id: U5WZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

557599:MKAN RS01815
gene id: 557599:MKAN_RS01815
uniprot id: U5WJP2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

557599:MKAN RS16900
gene id: 557599:MKAN_RS16900
uniprot id: U5WVF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

557599:MKAN RS09410
gene id: 557599:MKAN_RS09410
uniprot id: U5WRA1
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS10525
gene id: 557599:MKAN_RS10525
uniprot id: U5WS70
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS25720
gene id: 557599:MKAN_RS25720
uniprot id: U5WZQ8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS02615
gene id: 557599:MKAN_RS02615
uniprot id: U5WK17
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS15930
gene id: 557599:MKAN_RS15930
uniprot id: U5WRE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.
messages: Probable oxidase that might be involved in lipid metabolism.

557599:MKAN RS23210
gene id: 557599:MKAN_RS23210
uniprot id: U5WVC8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

557599:MKAN RS25100
gene id: 557599:MKAN_RS25100
uniprot id: U5WWA0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS15805
gene id: 557599:MKAN_RS15805
uniprot id: U5WR72
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS13870
gene id: 557599:MKAN_RS13870
uniprot id: U5WQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

557599:MKAN RS19130
gene id: 557599:MKAN_RS19130
uniprot id: U5WT36
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

557599:MKAN RS24120
gene id: 557599:MKAN_RS24120
uniprot id: U5WWD4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS24625
gene id: 557599:MKAN_RS24625
uniprot id: U5WZ46
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

557599:MKAN RS05840
gene id: 557599:MKAN_RS05840
uniprot id: U5WPQ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

557599:MKAN RS18240
gene id: 557599:MKAN_RS18240
uniprot id: U5WSP0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS21500
gene id: 557599:MKAN_RS21500
uniprot id: U5WXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

557599:MKAN RS24400
gene id: 557599:MKAN_RS24400
uniprot id: U5WWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

557599:MKAN RS06140
gene id: 557599:MKAN_RS06140
uniprot id: U5WPG6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

557599:MKAN RS01540
gene id: 557599:MKAN_RS01540
uniprot id: U5WM90
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS27850
gene id: 557599:MKAN_RS27850
uniprot id: U5WZN6
names: Similarity
messages: Belongs to the SsuD family.

557599:MKAN RS23365
gene id: 557599:MKAN_RS23365
uniprot id: U5WVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

557599:MKAN RS22620
gene id: 557599:MKAN_RS22620
uniprot id: U5WY36
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

557599:MKAN RS25615
gene id: 557599:MKAN_RS25615
uniprot id: U5WWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

557599:MKAN RS00100
gene id: 557599:MKAN_RS00100
uniprot id: U5WI48
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

557599:MKAN RS18565
gene id: 557599:MKAN_RS18565
uniprot id: U5WWD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

557599:MKAN RS19905
gene id: 557599:MKAN_RS19905
uniprot id: U5WX15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

557599:MKAN RS18940
gene id: 557599:MKAN_RS18940
uniprot id: U5WST5
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS20675
gene id: 557599:MKAN_RS20675
uniprot id: U5WX68
names: Similarity
messages: Belongs to the DEAD box helicase family.

557599:MKAN RS18355
gene id: 557599:MKAN_RS18355
uniprot id: U5WSQ8
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS05095
gene id: 557599:MKAN_RS05095
uniprot id: U5WNZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

557599:MKAN RS06955
gene id: 557599:MKAN_RS06955
uniprot id: U5WLN6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

557599:MKAN RS21285
gene id: 557599:MKAN_RS21285
uniprot id: U5WUB2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

557599:MKAN RS23185
gene id: 557599:MKAN_RS23185
uniprot id: U5WVC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

557599:MKAN RS14290
gene id: 557599:MKAN_RS14290
uniprot id: U5WU24
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS01015
gene id: 557599:MKAN_RS01015
uniprot id: U5WIQ3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS26580
gene id: 557599:MKAN_RS26580
uniprot id: U5WWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

557599:MKAN RS22955
gene id: 557599:MKAN_RS22955
uniprot id: U5WYL0
names: Similarity
messages: Belongs to the thioesterase family.

557599:MKAN RS07790
gene id: 557599:MKAN_RS07790
uniprot id: U5WMT5
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS15315
gene id: 557599:MKAN_RS15315
uniprot id: U5WUA5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS08605
gene id: 557599:MKAN_RS08605
uniprot id: U5WML2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS12135
gene id: 557599:MKAN_RS12135
uniprot id: U5WSZ5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

557599:MKAN RS08375
gene id: 557599:MKAN_RS08375
uniprot id: U5WMG8
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS08445
gene id: 557599:MKAN_RS08445
uniprot id: U5WMB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

557599:MKAN RS07030
gene id: 557599:MKAN_RS07030
uniprot id: U5WLP7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

557599:MKAN RS16635
gene id: 557599:MKAN_RS16635
uniprot id: U5WSE9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

557599:MKAN RS08220
gene id: 557599:MKAN_RS08220
uniprot id: U5WM80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

557599:MKAN RS27170
gene id: 557599:MKAN_RS27170
uniprot id: U5WXX1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

557599:MKAN RS10025
gene id: 557599:MKAN_RS10025
uniprot id: U5WS06
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

557599:MKAN RS12550
gene id: 557599:MKAN_RS12550
uniprot id: U5WQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

557599:MKAN RS04120
gene id: 557599:MKAN_RS04120
uniprot id: U5WNK6
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS23645
gene id: 557599:MKAN_RS23645
uniprot id: U5WYP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS04720
gene id: 557599:MKAN_RS04720
uniprot id: U5WP76
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

557599:MKAN RS19690
gene id: 557599:MKAN_RS19690
uniprot id: U5WWL1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

557599:MKAN RS03465
gene id: 557599:MKAN_RS03465
uniprot id: U5WK00
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS26860
gene id: 557599:MKAN_RS26860
uniprot id: U5WWY0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

557599:MKAN RS08750
gene id: 557599:MKAN_RS08750
uniprot id: U5WQU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

557599:MKAN RS14035
gene id: 557599:MKAN_RS14035
uniprot id: U5WQ75
names: Similarity
messages: Belongs to the Nudix hydrolase family.

557599:MKAN RS18730
gene id: 557599:MKAN_RS18730
uniprot id: U5WSP6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

557599:MKAN RS00260
gene id: 557599:MKAN_RS00260
uniprot id: U5WIC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

557599:MKAN RS19600
gene id: 557599:MKAN_RS19600
uniprot id: U5WU03
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS26850
gene id: 557599:MKAN_RS26850
uniprot id: U5X0Q3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

557599:MKAN RS13550
gene id: 557599:MKAN_RS13550
uniprot id: U5WQS1
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

557599:MKAN RS25885
gene id: 557599:MKAN_RS25885
uniprot id: U5X0A2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

557599:MKAN RS22460
gene id: 557599:MKAN_RS22460
uniprot id: U5WY04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

557599:MKAN RS18785
gene id: 557599:MKAN_RS18785
uniprot id: U5WSQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

557599:MKAN RS29520
gene id: 557599:MKAN_RS29520
uniprot id: U5WP03
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS10735
gene id: 557599:MKAN_RS10735
uniprot id: U5WNH0
names: Similarity
messages: Belongs to the HIBADH-related family.

557599:MKAN RS19390
gene id: 557599:MKAN_RS19390
uniprot id: U5WWF3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS18185
gene id: 557599:MKAN_RS18185
uniprot id: U5WSN1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

557599:MKAN RS08550
gene id: 557599:MKAN_RS08550
uniprot id: U5WMD2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

557599:MKAN RS19335
gene id: 557599:MKAN_RS19335
uniprot id: U5WWE4
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS07505
gene id: 557599:MKAN_RS07505
uniprot id: U5X1Q3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS21290
gene id: 557599:MKAN_RS21290
uniprot id: U5WXF9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS02245
gene id: 557599:MKAN_RS02245
uniprot id: U5WJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

557599:MKAN RS00535
gene id: 557599:MKAN_RS00535
uniprot id: U5WIH7
names: Similarity
messages: Belongs to the Apa family.

557599:MKAN RS08070
gene id: 557599:MKAN_RS08070
uniprot id: U5WQW8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

557599:MKAN RS25165
gene id: 557599:MKAN_RS25165
uniprot id: U5WWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS15240
gene id: 557599:MKAN_RS15240
uniprot id: U5WU94
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

557599:MKAN RS06055
gene id: 557599:MKAN_RS06055
uniprot id: U5WL48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

557599:MKAN RS08905
gene id: 557599:MKAN_RS08905
uniprot id: U5WQW6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS12650
gene id: 557599:MKAN_RS12650
uniprot id: U5WPQ7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS15980
gene id: 557599:MKAN_RS15980
uniprot id: U5WUL9
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS18525
gene id: 557599:MKAN_RS18525
uniprot id: U5WST6
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS04555
gene id: 557599:MKAN_RS04555
uniprot id: U5WNQ7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS27760
gene id: 557599:MKAN_RS27760
uniprot id: U5X328
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS17280
gene id: 557599:MKAN_RS17280
uniprot id: U5WRX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor.
messages: Belongs to the anti-sigma-K factor family.
messages: Cell membrane
messages: The cytosolic domain interacts with sigma factor SigK.

557599:MKAN RS23545
gene id: 557599:MKAN_RS23545
uniprot id: U5WYM8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

557599:MKAN RS26090
gene id: 557599:MKAN_RS26090
uniprot id: U5WZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS05125
gene id: 557599:MKAN_RS05125
uniprot id: U5WP01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

557599:MKAN RS09100
gene id: 557599:MKAN_RS09100
uniprot id: U5WRG1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS02925
gene id: 557599:MKAN_RS02925
uniprot id: U5WK71
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

557599:MKAN RS26945
gene id: 557599:MKAN_RS26945
uniprot id: U5WXT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS04055
gene id: 557599:MKAN_RS04055
uniprot id: U5WKV6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

557599:MKAN RS03505
gene id: 557599:MKAN_RS03505
uniprot id: U5WNJ0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

557599:MKAN RS20025
gene id: 557599:MKAN_RS20025
uniprot id: U5WWQ8
names: Similarity
messages: Belongs to the FPG family.

557599:MKAN RS07020
gene id: 557599:MKAN_RS07020
uniprot id: U5WQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS25300
gene id: 557599:MKAN_RS25300
uniprot id: U5WWD7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

557599:MKAN RS01445
gene id: 557599:MKAN_RS01445
uniprot id: U5WMJ7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS03430
gene id: 557599:MKAN_RS03430
uniprot id: U5WKG8
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

557599:MKAN RS16985
gene id: 557599:MKAN_RS16985
uniprot id: U5WV41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

557599:MKAN RS04445
gene id: 557599:MKAN_RS04445
uniprot id: U5WKI8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

557599:MKAN RS06040
gene id: 557599:MKAN_RS06040
uniprot id: U5WPE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS27475
gene id: 557599:MKAN_RS27475
uniprot id: U5WY20
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS00455
gene id: 557599:MKAN_RS00455
uniprot id: U5WIG0
names: Similarity
messages: Belongs to the arginase family.

557599:MKAN RS10720
gene id: 557599:MKAN_RS10720
uniprot id: U5WRT0
names: Similarity
messages: Belongs to the GARS family.

557599:MKAN RS08420
gene id: 557599:MKAN_RS08420
uniprot id: U5WMA8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

557599:MKAN RS04655
gene id: 557599:MKAN_RS04655
uniprot id: U5WNS3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

557599:MKAN RS19110
gene id: 557599:MKAN_RS19110
uniprot id: U5WWA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

557599:MKAN RS17295
gene id: 557599:MKAN_RS17295
uniprot id: U5WVM7
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS01475
gene id: 557599:MKAN_RS01475
uniprot id: U5WJI1
names: Similarity
messages: Belongs to the universal stress protein A family.

557599:MKAN RS23830
gene id: 557599:MKAN_RS23830
uniprot id: U5WZ81
names: Similarity
messages: Belongs to the peptidase M16 family.

557599:MKAN RS03725
gene id: 557599:MKAN_RS03725
uniprot id: U5WNM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

557599:MKAN RS12890
gene id: 557599:MKAN_RS12890
uniprot id: U5WTG1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

557599:MKAN RS03790
gene id: 557599:MKAN_RS03790
uniprot id: U5WK34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

557599:MKAN RS22455
gene id: 557599:MKAN_RS22455
uniprot id: U5WUW8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

557599:MKAN RS16690
gene id: 557599:MKAN_RS16690
uniprot id: U5WVC1
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

557599:MKAN RS08745
gene id: 557599:MKAN_RS08745
uniprot id: U5WMP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

557599:MKAN RS19240
gene id: 557599:MKAN_RS19240
uniprot id: U5WWP7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS00720
gene id: 557599:MKAN_RS00720
uniprot id: U5WIL1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS26935
gene id: 557599:MKAN_RS26935
uniprot id: U5X0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

557599:MKAN RS13930
gene id: 557599:MKAN_RS13930
uniprot id: U5WQB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

557599:MKAN RS07620
gene id: 557599:MKAN_RS07620
uniprot id: U5WQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

557599:MKAN RS18660
gene id: 557599:MKAN_RS18660
uniprot id: U5WW22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

557599:MKAN RS17775
gene id: 557599:MKAN_RS17775
uniprot id: U5WT33
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS05135
gene id: 557599:MKAN_RS05135
uniprot id: U5WLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

557599:MKAN RS28335
gene id: 557599:MKAN_RS28335
uniprot id: U5X3A9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

557599:MKAN RS00580
gene id: 557599:MKAN_RS00580
uniprot id: U5WIE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS25380
gene id: 557599:MKAN_RS25380
uniprot id: U5WW50
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

557599:MKAN RS18840
gene id: 557599:MKAN_RS18840
uniprot id: U5WSY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

557599:MKAN RS25405
gene id: 557599:MKAN_RS25405
uniprot id: U5WW58
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS01255
gene id: 557599:MKAN_RS01255
uniprot id: U5WJE8
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS19155
gene id: 557599:MKAN_RS19155
uniprot id: U5WT39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

557599:MKAN RS12180
gene id: 557599:MKAN_RS12180
uniprot id: U5WPH1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS18795
gene id: 557599:MKAN_RS18795
uniprot id: U5WW49
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

557599:MKAN RS12205
gene id: 557599:MKAN_RS12205
uniprot id: U5WPI7
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

557599:MKAN RS26450
gene id: 557599:MKAN_RS26450
uniprot id: U5WWR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

557599:MKAN RS03715
gene id: 557599:MKAN_RS03715
uniprot id: U5WK41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

557599:MKAN RS28105
gene id: 557599:MKAN_RS28105
uniprot id: U5X2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

557599:MKAN RS26660
gene id: 557599:MKAN_RS26660
uniprot id: U5X0M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

557599:MKAN RS21270
gene id: 557599:MKAN_RS21270
uniprot id: U5WXT2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

557599:MKAN RS00320
gene id: 557599:MKAN_RS00320
uniprot id: U5WID4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

557599:MKAN RS01585
gene id: 557599:MKAN_RS01585
uniprot id: U5WJ36
names: Similarity
messages: Belongs to the AHA1 family.

557599:MKAN RS25880
gene id: 557599:MKAN_RS25880
uniprot id: U5WZU4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

557599:MKAN RS21445
gene id: 557599:MKAN_RS21445
uniprot id: U5WXW0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

557599:MKAN RS05285
gene id: 557599:MKAN_RS05285
uniprot id: U5WKR7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

557599:MKAN RS18550
gene id: 557599:MKAN_RS18550
uniprot id: U5WSL8
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

557599:MKAN RS02600
gene id: 557599:MKAN_RS02600
uniprot id: U5WJH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

557599:MKAN RS17355
gene id: 557599:MKAN_RS17355
uniprot id: U5WVN9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS25645
gene id: 557599:MKAN_RS25645
uniprot id: U5WZM8
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS16150
gene id: 557599:MKAN_RS16150
uniprot id: U5WRI7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

557599:MKAN RS08625
gene id: 557599:MKAN_RS08625
uniprot id: U5WN69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

557599:MKAN RS05700
gene id: 557599:MKAN_RS05700
uniprot id: U5WLM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS02110
gene id: 557599:MKAN_RS02110
uniprot id: U5WJT5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

557599:MKAN RS00825
gene id: 557599:MKAN_RS00825
uniprot id: U5WLU0
names: Similarity
messages: Belongs to the UPF0045 family.

557599:MKAN RS15715
gene id: 557599:MKAN_RS15715
uniprot id: U5WR59
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS18110
gene id: 557599:MKAN_RS18110
uniprot id: U5WSM0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

557599:MKAN RS09290
gene id: 557599:MKAN_RS09290
uniprot id: U5WMT1
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS23015
gene id: 557599:MKAN_RS23015
uniprot id: U5WV01
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

557599:MKAN RS17955
gene id: 557599:MKAN_RS17955
uniprot id: U5WT61
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

557599:MKAN RS15880
gene id: 557599:MKAN_RS15880
uniprot id: U5WRE0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

557599:MKAN RS11710
gene id: 557599:MKAN_RS11710
uniprot id: U5WP59
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

557599:MKAN RS23630
gene id: 557599:MKAN_RS23630
uniprot id: U5WW41
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

557599:MKAN RS21175
gene id: 557599:MKAN_RS21175
uniprot id: U5WU06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

557599:MKAN RS16920
gene id: 557599:MKAN_RS16920
uniprot id: U5WSK0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

557599:MKAN RS18855
gene id: 557599:MKAN_RS18855
uniprot id: U5WTL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

557599:MKAN RS16720
gene id: 557599:MKAN_RS16720
uniprot id: U5WVC9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS06635
gene id: 557599:MKAN_RS06635
uniprot id: U5WM68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

557599:MKAN RS06090
gene id: 557599:MKAN_RS06090
uniprot id: U5WPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

557599:MKAN RS00705
gene id: 557599:MKAN_RS00705
uniprot id: U5WM14
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS12770
gene id: 557599:MKAN_RS12770
uniprot id: U5WPL5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

557599:MKAN RS18750
gene id: 557599:MKAN_RS18750
uniprot id: U5WWG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

557599:MKAN RS00685
gene id: 557599:MKAN_RS00685
uniprot id: U5WIG6
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS01665
gene id: 557599:MKAN_RS01665
uniprot id: U5WMA9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

557599:MKAN RS03405
gene id: 557599:MKAN_RS03405
uniprot id: U5WKG4
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS26015
gene id: 557599:MKAN_RS26015
uniprot id: U5X0C4
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS18965
gene id: 557599:MKAN_RS18965
uniprot id: U5WSU2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

557599:MKAN RS28195
gene id: 557599:MKAN_RS28195
uniprot id: U5X384
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

557599:MKAN RS14785
gene id: 557599:MKAN_RS14785
uniprot id: U5WUB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS21920
gene id: 557599:MKAN_RS21920
uniprot id: U5WY31
names: Similarity
messages: Belongs to the heat shock protein 70 family.

557599:MKAN RS15955
gene id: 557599:MKAN_RS15955
uniprot id: U5WRF3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS00345
gene id: 557599:MKAN_RS00345
uniprot id: U5WID9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

557599:MKAN RS09645
gene id: 557599:MKAN_RS09645
uniprot id: U5WNU8
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS22905
gene id: 557599:MKAN_RS22905
uniprot id: U5WYK0
names: Similarity
messages: Belongs to the acyltransferase PapA5 family.

557599:MKAN RS17935
gene id: 557599:MKAN_RS17935
uniprot id: U5WSC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS25705
gene id: 557599:MKAN_RS25705
uniprot id: U5WX64
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

557599:MKAN RS22360
gene id: 557599:MKAN_RS22360
uniprot id: U5WYA4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

557599:MKAN RS12605
gene id: 557599:MKAN_RS12605
uniprot id: U5WSV4
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

557599:MKAN RS11635
gene id: 557599:MKAN_RS11635
uniprot id: U5WP44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

557599:MKAN RS18470
gene id: 557599:MKAN_RS18470
uniprot id: U5WSS8
names: Similarity
messages: Belongs to the UPF0336 family.

557599:MKAN RS02270
gene id: 557599:MKAN_RS02270
uniprot id: U5WJ97
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

557599:MKAN RS05515
gene id: 557599:MKAN_RS05515
uniprot id: U5WLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

557599:MKAN RS00245
gene id: 557599:MKAN_RS00245
uniprot id: U5WLT6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS02920
gene id: 557599:MKAN_RS02920
uniprot id: U5WN78
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

557599:MKAN RS17915
gene id: 557599:MKAN_RS17915
uniprot id: U5WSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

557599:MKAN RS31410
gene id: 557599:MKAN_RS31410
uniprot id: U5WTR0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS16980
gene id: 557599:MKAN_RS16980
uniprot id: U5WRX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.
messages: Homodimer.

557599:MKAN RS19760
gene id: 557599:MKAN_RS19760
uniprot id: U5WTH1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS16005
gene id: 557599:MKAN_RS16005
uniprot id: U5WUM3
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

557599:MKAN RS06845
gene id: 557599:MKAN_RS06845
uniprot id: U5WQC0
names: Similarity
messages: Belongs to the CdaR family.

557599:MKAN RS19610
gene id: 557599:MKAN_RS19610
uniprot id: U5WTD7
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS02995
gene id: 557599:MKAN_RS02995
uniprot id: U5WN95
names: Similarity
messages: Belongs to the glutamine synthetase family.

557599:MKAN RS06685
gene id: 557599:MKAN_RS06685
uniprot id: U5WQ95
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS00375
gene id: 557599:MKAN_RS00375
uniprot id: U5WIE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

557599:MKAN RS06415
gene id: 557599:MKAN_RS06415
uniprot id: U5WLG5
names: Subcellular Location Annotation
messages: Cell membrane

557599:MKAN RS21390
gene id: 557599:MKAN_RS21390
uniprot id: U5WXH9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

557599:MKAN RS13205
gene id: 557599:MKAN_RS13205
uniprot id: U5WPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

557599:MKAN RS06080
gene id: 557599:MKAN_RS06080
uniprot id: U5WL53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

557599:MKAN RS24230
gene id: 557599:MKAN_RS24230
uniprot id: U5WVU9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

557599:MKAN RS11515
gene id: 557599:MKAN_RS11515
uniprot id: U5WNU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

557599:MKAN RS02610
gene id: 557599:MKAN_RS02610
uniprot id: U5WN21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS27095
gene id: 557599:MKAN_RS27095
uniprot id: U5WXW3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS00240
gene id: 557599:MKAN_RS00240
uniprot id: U5WLI0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS15845
gene id: 557599:MKAN_RS15845
uniprot id: U5WUY2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS24735
gene id: 557599:MKAN_RS24735
uniprot id: U5WZ66
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS05400
gene id: 557599:MKAN_RS05400
uniprot id: U5WKY3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

557599:MKAN RS18875
gene id: 557599:MKAN_RS18875
uniprot id: U5WW63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

557599:MKAN RS26480
gene id: 557599:MKAN_RS26480
uniprot id: U5WWS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

557599:MKAN RS18625
gene id: 557599:MKAN_RS18625
uniprot id: U5WSM9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

557599:MKAN RS23665
gene id: 557599:MKAN_RS23665
uniprot id: U5WVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

557599:MKAN RS09635
gene id: 557599:MKAN_RS09635
uniprot id: U5WRD8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS14230
gene id: 557599:MKAN_RS14230
uniprot id: U5WU15
names: Similarity
messages: Belongs to the UPF0749 family.

557599:MKAN RS17205
gene id: 557599:MKAN_RS17205
uniprot id: U5WS23
names: Similarity
messages: Belongs to the AAA ATPase family.

557599:MKAN RS27040
gene id: 557599:MKAN_RS27040
uniprot id: U5X0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS03225
gene id: 557599:MKAN_RS03225
uniprot id: U5WJS6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

557599:MKAN RS06070
gene id: 557599:MKAN_RS06070
uniprot id: U5WPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

557599:MKAN RS22470
gene id: 557599:MKAN_RS22470
uniprot id: U5WVG4
names: Similarity
messages: Belongs to the WrbA family.

557599:MKAN RS10955
gene id: 557599:MKAN_RS10955
uniprot id: U5WNR0
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS07730
gene id: 557599:MKAN_RS07730
uniprot id: U5WQC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

557599:MKAN RS02830
gene id: 557599:MKAN_RS02830
uniprot id: U5WJJ6
names: Similarity
messages: Belongs to the asparagine synthetase family.

557599:MKAN RS26465
gene id: 557599:MKAN_RS26465
uniprot id: U5X036
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS25010
gene id: 557599:MKAN_RS25010
uniprot id: U5WWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

557599:MKAN RS05200
gene id: 557599:MKAN_RS05200
uniprot id: U5WP16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

557599:MKAN RS25220
gene id: 557599:MKAN_RS25220
uniprot id: U5WW17
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

557599:MKAN RS19705
gene id: 557599:MKAN_RS19705
uniprot id: U5WT74
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS27190
gene id: 557599:MKAN_RS27190
uniprot id: U5X0V7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS09475
gene id: 557599:MKAN_RS09475
uniprot id: U5WN02
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

557599:MKAN RS16825
gene id: 557599:MKAN_RS16825
uniprot id: U5WSI6
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS24020
gene id: 557599:MKAN_RS24020
uniprot id: U5WWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

557599:MKAN RS21440
gene id: 557599:MKAN_RS21440
uniprot id: U5WXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
messages: Membrane

557599:MKAN RS04370
gene id: 557599:MKAN_RS04370
uniprot id: U5WKH6
names: Similarity
messages: Belongs to the peptidase U62 family.

557599:MKAN RS23910
gene id: 557599:MKAN_RS23910
uniprot id: U5WZ94
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS24920
gene id: 557599:MKAN_RS24920
uniprot id: U5WW62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

557599:MKAN RS16165
gene id: 557599:MKAN_RS16165
uniprot id: U5WS72
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS03415
gene id: 557599:MKAN_RS03415
uniprot id: U5WJY8
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS06395
gene id: 557599:MKAN_RS06395
uniprot id: U5WQ04
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

557599:MKAN RS18595
gene id: 557599:MKAN_RS18595
uniprot id: U5WTH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

557599:MKAN RS03655
gene id: 557599:MKAN_RS03655
uniprot id: U5WN88
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

557599:MKAN RS20330
gene id: 557599:MKAN_RS20330
uniprot id: U5WUG2
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

557599:MKAN RS22545
gene id: 557599:MKAN_RS22545
uniprot id: U5WY22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

557599:MKAN RS20055
gene id: 557599:MKAN_RS20055
uniprot id: U5WX42
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS25520
gene id: 557599:MKAN_RS25520
uniprot id: U5WWH3
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS12045
gene id: 557599:MKAN_RS12045
uniprot id: U5WSY2
names: Subcellular Location Annotation
messages: Cytoplasm

557599:MKAN RS03150
gene id: 557599:MKAN_RS03150
uniprot id: U5WJR0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

557599:MKAN RS13855
gene id: 557599:MKAN_RS13855
uniprot id: U5WQ96
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS03230
gene id: 557599:MKAN_RS03230
uniprot id: C5MTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm

557599:MKAN RS24785
gene id: 557599:MKAN_RS24785
uniprot id: U5WW37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

557599:MKAN RS06575
gene id: 557599:MKAN_RS06575
uniprot id: U5WQ35
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

557599:MKAN RS11725
gene id: 557599:MKAN_RS11725
uniprot id: U5WZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

557599:MKAN RS00330
gene id: 557599:MKAN_RS00330
uniprot id: U5WLV1
names: Similarity
messages: Belongs to the UPF0749 family.

557599:MKAN RS18410
gene id: 557599:MKAN_RS18410
uniprot id: U5WVX8
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

557599:MKAN RS05245
gene id: 557599:MKAN_RS05245
uniprot id: U5WLF9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

557599:MKAN RS10380
gene id: 557599:MKAN_RS10380
uniprot id: U5WS50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

557599:MKAN RS07300
gene id: 557599:MKAN_RS07300
uniprot id: U5WQK4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

557599:MKAN RS06945
gene id: 557599:MKAN_RS06945
uniprot id: U5WQE0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS05405
gene id: 557599:MKAN_RS05405
uniprot id: U5WP51
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

557599:MKAN RS16155
gene id: 557599:MKAN_RS16155
uniprot id: U5WUQ3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS22765
gene id: 557599:MKAN_RS22765
uniprot id: U5WYH3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS08455
gene id: 557599:MKAN_RS08455
uniprot id: U5WQP8
names: Similarity
messages: Belongs to the peptidase S1C family.

557599:MKAN RS19055
gene id: 557599:MKAN_RS19055
uniprot id: U5WW97
names: Subcellular Location Annotation
messages: Membrane

557599:MKAN RS02940
gene id: 557599:MKAN_RS02940
uniprot id: U5WMW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

557599:MKAN RS18480
gene id: 557599:MKAN_RS18480
uniprot id: U5WVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

557599:MKAN RS17840
gene id: 557599:MKAN_RS17840
uniprot id: U5WW21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

557599:MKAN RS27490
gene id: 557599:MKAN_RS27490
uniprot id: U5X0J6
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS09190
gene id: 557599:MKAN_RS09190
uniprot id: U5WMW9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS26155
gene id: 557599:MKAN_RS26155
uniprot id: U5WWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

557599:MKAN RS00655
gene id: 557599:MKAN_RS00655
uniprot id: U5WJ18
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

557599:MKAN RS29225
gene id: 557599:MKAN_RS29225
uniprot id: U5WJK7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS17420
gene id: 557599:MKAN_RS17420
uniprot id: U5WSU4
names: Similarity
messages: Belongs to the CFA/CMAS family.

557599:MKAN RS19160
gene id: 557599:MKAN_RS19160
uniprot id: U5WWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

557599:MKAN RS20300
gene id: 557599:MKAN_RS20300
uniprot id: U5WXD4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

557599:MKAN RS17385
gene id: 557599:MKAN_RS17385
uniprot id: U5WYK9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

557599:MKAN RS10765
gene id: 557599:MKAN_RS10765
uniprot id: U5WNN9
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS21225
gene id: 557599:MKAN_RS21225
uniprot id: U5WUV7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS25540
gene id: 557599:MKAN_RS25540
uniprot id: U5WW85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Homopentamer.

557599:MKAN RS07485
gene id: 557599:MKAN_RS07485
uniprot id: U5WQN6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

557599:MKAN RS09655
gene id: 557599:MKAN_RS09655
uniprot id: U5WN92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

557599:MKAN RS26505
gene id: 557599:MKAN_RS26505
uniprot id: U5WWS6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

557599:MKAN RS02455
gene id: 557599:MKAN_RS02455
uniprot id: U5WJZ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

557599:MKAN RS26470
gene id: 557599:MKAN_RS26470
uniprot id: U5X0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

557599:MKAN RS11285
gene id: 557599:MKAN_RS11285
uniprot id: U5WNX2
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

557599:MKAN RS03455
gene id: 557599:MKAN_RS03455
uniprot id: U5WKH5
names: Similarity
messages: Belongs to the WXG100 family.

557599:MKAN RS02230
gene id: 557599:MKAN_RS02230
uniprot id: U5WMJ1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

557599:MKAN RS20275
gene id: 557599:MKAN_RS20275
uniprot id: U5WXC8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

557599:MKAN RS24060
gene id: 557599:MKAN_RS24060
uniprot id: U5WYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

557599:MKAN RS23805
gene id: 557599:MKAN_RS23805
uniprot id: U5WZ77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

557599:MKAN RS21730
gene id: 557599:MKAN_RS21730
uniprot id: U5WUI4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

557599:MKAN RS05610
gene id: 557599:MKAN_RS05610
uniprot id: U5WP83
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

557599:MKAN RS19985
gene id: 557599:MKAN_RS19985
uniprot id: U5WWQ4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

557599:MKAN RS26100
gene id: 557599:MKAN_RS26100
uniprot id: U5WXE2
names: Function
names: Subunit
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

557599:MKAN RS24325
gene id: 557599:MKAN_RS24325
uniprot id: U5WVM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

557599:MKAN RS06770
gene id: 557599:MKAN_RS06770
uniprot id: U5WLK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

557599:MKAN RS10940
gene id: 557599:MKAN_RS10940
uniprot id: U5WSC4
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

557599:MKAN RS12735
gene id: 557599:MKAN_RS12735
uniprot id: U5WTD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

557599:MKAN RS12530
gene id: 557599:MKAN_RS12530
uniprot id: U5WPH7
names: Similarity
messages: Belongs to the peptidase C56 family.

557599:MKAN RS23200
gene id: 557599:MKAN_RS23200
uniprot id: U5WVW5
names: Similarity
messages: Belongs to the DprA/Smf family.

557599:MKAN RS24000
gene id: 557599:MKAN_RS24000
uniprot id: U5WVH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.